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The article discusses a program to transform the International Federation of Associations of Pharmaceutical Physicians (IFAPP). It says the nonprofit organization's mission is to promote pharmaceutical medicine. It notes that the Global Strategy Working Party (GSW) was established by the IFAPP Executive Committee in June 2007 with the aim of helping the organization to explore options, discuss issues and identify possible solutions. It adds that some projects included in the effort to transform IFAPP focus on interacting with other associations.

Reports on the challenges faced by clinicians in drafting a project plan for clinical trials. Benefits of implementing a performance metrics system in all operational departments; Efficacy of performance metrics in tracking the efficiency of the cooperation with study sites and contract research organizations; Maintenance of sophisticated systems for research and development timeline, cost, and productivity tracking based on the input from research-based pharmaceutical firms.

Keywords: research ethics; data science; medicines development; privacy protection; data sharing; declaration of Helsinki; declaration of Taipei EN research ethics data science medicines development privacy protection data sharing declaration of Helsinki declaration of Taipei N.PAG N.PAG 1 02/09/21 20210208 NES 210208 In the original article, there were errors. Research ethics, data science, medicines development, privacy protection, data sharing, declaration of Helsinki, declaration of Taipei. [Extracted from the article]

Depending on its location, size, and proximity to the cardiac structures, an intrapericardial teratoma may lead to severe circulatory disturbances and even fetal demise. A 34-year-old G2P1 presented at 20w5d with a solid cystic mass in the right thorax of the fetus, originating from the right atrium or lung, with signs of non-immune fetal hydrops, soon resulting in intrauterine fetal death. Detailed post-mortem autopsy revealed signs of hydrops fetalis universalis due to a spherical tumor mass originating from the aortic root. Histologic examination of the tumor showed the characteristic morphology of a teratoma. A 1.6-Mb microdeletion at 3q29 was identified by single nucleotide polymorphism array. This is the first report presenting the diagnosis of an intrapericardial teratoma in a fetus with a microdeletion of 3q29. Intrapericardial teratoma has a poor prognosis and the fetal outcome relies on the development of hydrops. A post-mortem examination is essential in order to make a definitive diagnosis, which underlines the status of the fetal pathologist and the need for interdisciplinary cooperation., Competing Interests: The authors declare that they have no conflict of interest., (Thieme. All rights reserved.)

Aim of the Study: The aim of the study is to examine the detection rates of malformations before and after the introduction of extended basic screening in Hesse by the Federal Joint Committee (Gemeinsamer Bundesausschuss, GQH) on July 1, 2013., Method: This is a retrospective, mainly exploratory data analysis of quality assurance data from the Office for Quality Assurance in Hesse (GQH). The data was collected in the period from January 1, 2010 to December 31, 2016 in the obstetric departments of the Hessian hospitals using documentation forms. The classification and evaluation of the diagnoses is based on ICD-10-GM-2019., Results: At least one malformation is present in 0.7% of the cases. With a share of 30.0%, most of the congenital malformations are from the musculoskeletal system. 12.2% of the malformations come from the facial cleft, closely followed by malformations of the circulatory system with 11.3%. The highest prenatal detection rate (PDR) is found in congenital malformations of the nervous system at 56.8%. The lowest PDR is found in those of the genital organs with 2.1%. The PDR of cardiovascular malformations is 32.9%. Overall, a PDR of 25.2% is achieved. There was no change in the number of prenatal malformation diagnoses after the introduction of extended basic ultrasound. The distribution of malformation diagnoses not detected prenatally to the organ systems also has not changed after the introduction., Conclusion: The introduction of extended basic ultrasound did not bring the desired improvement with regard to the PDR in Hesse. Alternative approaches should be considered., Competing Interests: The authors declare that they have no conflict of interest., (Thieme. All rights reserved.)