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53. Ability of Adeno-Associated Virus Serotype 8-Mediated Hepatic Expression of Acid α-Glucosidase to Correct the Biochemical and Motor Function Deficits of Presymptomatic and Symptomatic Pompe Mice

54. Timing of Therapeutic Intervention Determines Functional and Survival Outcomes in a Mouse Model of Late Infantile Batten Disease

55. Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

58. 695. Low-Frequency Ultrasound Increases Non- Viral Lung Gene Transfer

79. Basis of Pulmonary Toxicity Associated with Cationic Lipid-Mediated Gene Transfer to the Mammalian Lung

80. Detailed Analysis of Structures and Formulations of Cationic Lipids for Efficient Gene Transfer to the Lung

81. Purification and Characterization of Recombinant Cystic Fibrosis Transmembrane Conductance Regulator from Chinese Hamster Ovary and Insect Cells

82. Repeated nebulisation of non-viral CFTRgene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

86. Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity.

90. Surfactant Protein-D and Surfactant Inhibit Endotoxin-Induced Pulmonary lnflammation.

93. Section 2: CATIONIC LIPOSOMES Chapter 7: Toxicity of Cationic Lipid-DNA Complexes.

94. Partial correction of the α-galactosidase A deficiency and reduction of glycolipid storage in Fabry mice using synthetic vectors.

96. Transforming growth factor–ß1 gene transfer ameliorates acute lung allograft rejection

97. Aerosolization of Cationic Lipid:pDNA ComplexesIn VitroOptimization of Nebulizer Parameters for Human Clinical Studies

98. Optimization of Formulations and Conditions for the Aerosol Delivery of Functional Cationic Lipid:DNA Complexes

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