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51. Soft tissue sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Author

Casali, P.G., Blay, J.Y., Aglietta, M., Alvegaard, T., Athanasou, N., Binh, B., Bonvalot, S., Boukovinas, I., De Alava, E., Dei Tos, A.P., Dileo, P., Eriksson, M., Ferrari, A., Ferrari, S., Garcia del Muro, S.F., Gronchi, A., Hall, K.S., Hassan, B., Hogendoorn, P.C., Hohenberger, P., Gelderblom, H., Grimer, R., Issels, R., Joensuu, H., Jost, L., Judson, I.R., Jurgens, H., Cesne, A. le, Leyvraz, S., Martin, J., Montemurro, M., Nishida, T., Patel, S., Reichardt, P., Robinson, M., Rutkowski, P., Schoffski, P., Schlemmer, M., Sleijfer, S., Graaf, W.T.A. van der, Vanel, D., Verweij, J., Wardelmann, E., and Whelan, J.

Subjects
Adult, Male, Radiotherapy, Biopsy, Incidence, Sarcoma, Hematology, Prognosis, soft tissue sarcomas, Combined Modality Therapy, Risk Assessment, Europe, Treatment Outcome, Oncology, Chemotherapy, Adjuvant, Translational research [ONCOL 3], Lymphatic Metastasis, Secondary Prevention, Humans, Female, Neoplasm Metastasis, Follow-Up Studies, Neoplasm Staging, Randomized Controlled Trials as Topic
Abstract

Item does not contain fulltext 01 mei 2010

Published
2010

52. Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Author

Casali, P.G., Blay, J.Y., Bertuzzi, A., Bielack, S., Bjerkehagen, B., Bonvalot, S., Boukovinas, I., Bruzzi, P., Dei Tos, A.P., Dileo, P., Eriksson, M., Fedenko, A., Ferrari, A., Ferrari, S., Gelderblom, H., Grimer, R., Gronchi, A., Haas, R. de, Hall, K.S., Hohenberger, P., Issels, R., Joensuu, H., Judson, I., Cesne, A. le, Litiere, S., Martin-Broto, J., Merimsky, O., Montemurro, M., Morosi, C., Picci, P., Ray-Coquard, I., Reichardt, P., Rutkowski, P., Schlemmer, M., Stacchiotti, S., Torri, V., Trama, A., Coevorden, F. van, Graaf, W.T.A. van der, Vanel, D., Wardelmann, E., Bolle, S., Capanna, R., Delaney, T., Doglietto, F., Fossati, P., Jeys, L., Kasper, B., Leithner, A., Radaeli, S., Scheipl, S., Tamborini, E., Uhl, M., Vleggert-Lankamp, C.L., Casali, P.G., Blay, J.Y., Bertuzzi, A., Bielack, S., Bjerkehagen, B., Bonvalot, S., Boukovinas, I., Bruzzi, P., Dei Tos, A.P., Dileo, P., Eriksson, M., Fedenko, A., Ferrari, A., Ferrari, S., Gelderblom, H., Grimer, R., Gronchi, A., Haas, R. de, Hall, K.S., Hohenberger, P., Issels, R., Joensuu, H., Judson, I., Cesne, A. le, Litiere, S., Martin-Broto, J., Merimsky, O., Montemurro, M., Morosi, C., Picci, P., Ray-Coquard, I., Reichardt, P., Rutkowski, P., Schlemmer, M., Stacchiotti, S., Torri, V., Trama, A., Coevorden, F. van, Graaf, W.T.A. van der, Vanel, D., Wardelmann, E., Bolle, S., Capanna, R., Delaney, T., Doglietto, F., Fossati, P., Jeys, L., Kasper, B., Leithner, A., Radaeli, S., Scheipl, S., Tamborini, E., Uhl, M., and Vleggert-Lankamp, C.L.

Abstract

Contains fulltext : 139063.pdf (publisher's version ) (Closed access)

Published
2014

53. Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Author

Casali, P.G., Blay, J.Y., Bertuzzi, A., Bielack, S., Bjerkehagen, B., Bonvalot, S., Boukovinas, I., Bruzzi, P., Dei Tos, A.P., Dileo, P., Eriksson, M., Fedenko, A., Ferrari, A., Ferrari, S., Gelderblom, H., Grimer, R., Gronchi, A., Haas, R, Hall, K.S., Hohenberger, P., Issels, R., Joensuu, H., Judson, I., Cesne, A. le, Litiere, S., Martin-Broto, J., Merimsky, O., Montemurro, M., Morosi, C., Picci, P., Ray-Coquard, I., Reichardt, P., Rutkowski, P., Schlemmer, M., Stacchiotti, S., Torri, V., Trama, A., Coevorden, F. van, Graaf, W.T.A. van der, Vanel, D., Wardelmann, E., Casali, P.G., Blay, J.Y., Bertuzzi, A., Bielack, S., Bjerkehagen, B., Bonvalot, S., Boukovinas, I., Bruzzi, P., Dei Tos, A.P., Dileo, P., Eriksson, M., Fedenko, A., Ferrari, A., Ferrari, S., Gelderblom, H., Grimer, R., Gronchi, A., Haas, R, Hall, K.S., Hohenberger, P., Issels, R., Joensuu, H., Judson, I., Cesne, A. le, Litiere, S., Martin-Broto, J., Merimsky, O., Montemurro, M., Morosi, C., Picci, P., Ray-Coquard, I., Reichardt, P., Rutkowski, P., Schlemmer, M., Stacchiotti, S., Torri, V., Trama, A., Coevorden, F. van, Graaf, W.T.A. van der, Vanel, D., and Wardelmann, E.

Abstract

Contains fulltext : 139108.pdf (publisher's version ) (Closed access)

Published
2014

54. Bone sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up

Author

Casali, P. G., Blay, J. -Y., Bertuzzi, A., Bielack, S., Bjerkehagen, B., Bonvalot, S., Boukovinas, I., Bruzzi, P., Tos, A. P. D., Dileo, P., Eriksson, M., Fedenko, A., Ferrari, A., Ferrari, S., Gelderblom, H., Grimer, R., Gronchi, A., Haas, R., Hall, K. S., Hohenberger, P., Issels, R., Joensuu, H., Judson, I., Cesne, A. L., Litiere, S., Martin-Broto, J., Merimsky, O., Montemurro, M., Morosi, C., Picci, P., Ray-Coquard, I., Reichardt, P., Rutkowski, P., Schlemmer, M., Stacchiotti, S., Torri, V., Trama, A., Van Coevorden, F., Van der Graaf, W., Vanel, D., Wardelmann, E., Bolle, S., Capanna, R., Delaney, T., Doglietto, Francesco, Fossati, P., Jeys, L., Kasper, B., Leithner, A., Norum, O. -J., Radaelli, S., Scheipl, S., Tamborini, E., Uhl, M., Vleggert-Lankamp, C. L. A., Doglietto F. (ORCID:0000-0002-7438-0734), Casali, P. G., Blay, J. -Y., Bertuzzi, A., Bielack, S., Bjerkehagen, B., Bonvalot, S., Boukovinas, I., Bruzzi, P., Tos, A. P. D., Dileo, P., Eriksson, M., Fedenko, A., Ferrari, A., Ferrari, S., Gelderblom, H., Grimer, R., Gronchi, A., Haas, R., Hall, K. S., Hohenberger, P., Issels, R., Joensuu, H., Judson, I., Cesne, A. L., Litiere, S., Martin-Broto, J., Merimsky, O., Montemurro, M., Morosi, C., Picci, P., Ray-Coquard, I., Reichardt, P., Rutkowski, P., Schlemmer, M., Stacchiotti, S., Torri, V., Trama, A., Van Coevorden, F., Van der Graaf, W., Vanel, D., Wardelmann, E., Bolle, S., Capanna, R., Delaney, T., Doglietto, Francesco, Fossati, P., Jeys, L., Kasper, B., Leithner, A., Norum, O. -J., Radaelli, S., Scheipl, S., Tamborini, E., Uhl, M., Vleggert-Lankamp, C. L. A., and Doglietto F. (ORCID:0000-0002-7438-0734)

Abstract

N/A

Published
2014

56. Cardiac markers (BNP, NT-pro-BNP, Troponin I, Troponin T, in female amateur runners before and up until three days after a marathon

Author

Frassl W, Kowoll R, Katz N, Speth M, Stangl A, Lars Brechtel, Joscht B, Lh, Boldt, Meier-Buttermilch R, Schlemmer M, Roecker L, and Hc, Gunga

Subjects
Adult, Cardiovascular Physiological Phenomena, Time Factors, Troponin T, Natriuretic Peptide, Brain, Physical Exertion, Troponin I, Humans, Female, Middle Aged, Biomarkers, Peptide Fragments, Running
Abstract

Transient cardiac ventricular dysfunction or sudden cardiac deaths have been reported for male athletes participating in marathon racing. Less is known about the myocardial response in females. We examined natriuretic peptides and cardiac troponins in female athletes after a marathon.At the 31st real,- Berlin Marathon plasma levels of NT-pro-BNP, BNP, cTnI and cTnT were measured in 15 women (age 35+/-6 years; finishing times between 3:22 h and 5:21 h) at four different time points (before, immediately after, day one and day three).An increase in [NT-pro-BNP] was observed immediately after the marathon (median [NT-pro-BNP] before: 39.6 pg ml(-1), after: 138.6 pg ml(-1), p=0.003) with a further increase on day one. [BNP] did not increase immediately after the marathon but increased on day one (median [BNP] before: 15 pg ml(-1), day one: 27.35 pg ml(-1), p=0.006). On day three, [NT-pro-BNP] and [BNP] returned to initial values. [cTnI] was under the detection limit prior to the marathon in all runners. [cTnT] was under the detection limit before the marathon except in one runner who presented a concentration of 0.03 ng ml(-1). Cardiac troponins (median [cTnl] after: 0.098 ng ml(-1), p=0.028; median [cTnT] after: 0.032 ng ml(-1), p=0.012) increased immediately after the marathon and returned to initial values on day one [cTnT] and three [cTnI].Parameters representing cardiac stress increased in females after a marathon. Different kinetics of natriuretic peptides BNP and NT-pro-BNP post-marathon could be due to their different half-lives and dependence on renal function. The increase of cTnI and cTnT may result from minor myocardial lesions.

Published
2008

63. Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Author

Casali, P.G., Blay, J.Y., Aglietta, M., Alvegaard, T., Athanasou, N., Binh, B., Bonvalot, S., Boukovinas, I., De Alava, E., Dei Tos, A.P., Dileo, P., Eriksson, M., Ferrari, A., Ferrari, S., Garcia del Muro, S.F., Gronchi, A., Hall, K.S., Hassan, B., Hogendoorn, P.C., Hohenberger, P., Gelderblom, H., Grimer, R., Issels, R., Joensuu, H., Jost, L., Judson, I., Jurgens, H., Cesne, A. le, Leyvraz, S., Martin, J., Montemurro, M., Nishida, T., Patel, S., Reichardt, P., Robinson, M., Rutkowski, P., Schoffski, P., Schlemmer, M., Sleijver, S., Graaf, W.T.A. van der, Vanel, D., Verweij, J., Wardelmann, E., Whelan, J., Casali, P.G., Blay, J.Y., Aglietta, M., Alvegaard, T., Athanasou, N., Binh, B., Bonvalot, S., Boukovinas, I., De Alava, E., Dei Tos, A.P., Dileo, P., Eriksson, M., Ferrari, A., Ferrari, S., Garcia del Muro, S.F., Gronchi, A., Hall, K.S., Hassan, B., Hogendoorn, P.C., Hohenberger, P., Gelderblom, H., Grimer, R., Issels, R., Joensuu, H., Jost, L., Judson, I., Jurgens, H., Cesne, A. le, Leyvraz, S., Martin, J., Montemurro, M., Nishida, T., Patel, S., Reichardt, P., Robinson, M., Rutkowski, P., Schoffski, P., Schlemmer, M., Sleijver, S., Graaf, W.T.A. van der, Vanel, D., Verweij, J., Wardelmann, E., and Whelan, J.

Abstract

1 mei 2010, Item does not contain fulltext

Published
2010

69. Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers.

Author

Valenti, G., Fraszl, W., Addabbo, F., Tamma, G., Procino, G., Satta, E., Cirillo, M., Santo, N.G. De, Drummer, C., Bellini, L., Kowoll, R., Schlemmer, M., Vogler, S., Kirsch, K.A., Svelto, M., Gunga, H.C., Valenti, G., Fraszl, W., Addabbo, F., Tamma, G., Procino, G., Satta, E., Cirillo, M., Santo, N.G. De, Drummer, C., Bellini, L., Kowoll, R., Schlemmer, M., Vogler, S., Kirsch, K.A., Svelto, M., and Gunga, H.C.

Abstract

Contains fulltext : 51180.pdf (publisher's version ) (Closed access), Here, we report the alterations in renal water handling in healthy volunteers during a 6 h thermoneutral water immersion at 34 to 36 degrees C. We found that water immersion is associated with a reversible increase in total urinary AQP2 excretion.

Published
2006

70. Initial and late resistance to imatinib in advanced gastrointestinal stromal. tumors are predicted by different prognostic factors: A European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group study

Author

UCL - Autre, Van Glabbeke, Martine, Verweij, J., Casali, PG, Le Cesne, A., Hohenberger, P, Ray-Coquard, I., Schlemmer, M, van Oosterom, AT, Goldstein, D, Sciot, Raf, Hogendoorn, PCW, Brown, M., Bertulli, R, Judson, IR, 10th Annual Meeting of the Connective-Tissue-Oncology-Society, UCL - Autre, Van Glabbeke, Martine, Verweij, J., Casali, PG, Le Cesne, A., Hohenberger, P, Ray-Coquard, I., Schlemmer, M, van Oosterom, AT, Goldstein, D, Sciot, Raf, Hogendoorn, PCW, Brown, M., Bertulli, R, Judson, IR, and 10th Annual Meeting of the Connective-Tissue-Oncology-Society

Abstract

Purpose The aim of this study was to identify factors predicting initial and late resistance of GI stromal tumor (GIST) patients to imatinib and to document the dose-response relationship in the prognostic subgroups. This study is based on the European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trials Group randomized trial comparing two doses of imatinib in advanced disease. Patients and Methods Initial resistance was defined as progression within 3 months of randomization, and late resistance was defined as progression beyond 3 months. Investigated cofactors include imatinib dose, age, sex, performance status, original disease site, site and size of lesions at trial entry, and baseline hematologic and biologic parameters. Results Initial resistance was recorded for 116 (12%) of 934 assessable patients and was independently predicted by the presence of lung and absence of liver metastases, low hemoglobin level, and high granulocyte count. Among 818 patients who were alive and progression free at 3 months, 347 subsequent progressions were recorded, and late resistance was independently predicted by high baseline granulocyte count, primary tumor outside of the stomach, large tumor size, and low initial imatinib dose. The impact of initial dose on late resistance was mainly significant in patients with a high baseline granulocyte count (> 5.10(9)/L) and in patients with tumors of GI origin outside of the stomach and small intestine. Conclusion Our study identifies patients for whom initial and/or long-term treatment needs to be improved and patients who require a high initial dose. Correlation of these results with immunohistochemistry and molecular parameters may further help to understand the biologic mechanisms of resistance.

Published
2005

72. Twelve versus 36 months of adjuvant imatinib (IM) as treatment of operable GIST with a high risk of recurrence: Final results of a randomized trial (SSGXVIII/AIO).

Author

Joensuu, H., primary, Eriksson, M., additional, Hatrmann, J., additional, Sundby Hall, K., additional, Schutte, J., additional, Reichardt, A., additional, Schlemmer, M., additional, Wardelmann, E., additional, Ramadori, G., additional, Al-Batran, S., additional, Nilsson, B. E., additional, Monge, O., additional, Kallio, R., additional, Sarlomo-Rikala, M., additional, Bono, P., additional, Leinonen, M., additional, Hohenberger, P., additional, Alvegard, T., additional, and Reichardt, P., additional

Published
2011
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76. Erhöhte Parameter der systemischen Inflammation korrelieren mit der erniedrigten Konzentration von Glutamin, Arginin und Citrullin im Plasma von Patienten mit soliden Tumoren unter Chemo- und Radiotherapie

Author

Suchner, U, primary, Schuler, U, additional, Duerr, EM, additional, Schäpers, B, additional, Degenhart, A, additional, Stockheim, B, additional, Stehle, P, additional, Alteheld, B, additional, Zwingers, T, additional, Zimmer, HG, additional, and Schlemmer, M, additional

Published
2010
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80. 275 Taxanes in angiosarcomas

Author

Schlemmer, M., primary, Reichardt, P., additional, Verweij, J., additional, Hartmann, J., additional, Judson, I., additional, Thyss, A., additional, Hogendoorn, P.C.W., additional, Marreaud, S., additional, and Van Glabbeke, M., additional

Published
2009
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91. Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

Author

Valenti, G., primary, Fraszl, W., additional, Addabbo, F., additional, Tamma, G., additional, Procino, G., additional, Satta, E., additional, Cirillo, M., additional, De Santo, N.G., additional, Drummer, C., additional, Bellini, L., additional, Kowoll, R., additional, Schlemmer, M., additional, Vogler, S., additional, Kirsch, K.A., additional, Svelto, M., additional, and Gunga, H.C., additional

Published
2006
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94. Risk assessment of early progression among 213 pts with high-risk soft tissue sarcomas (HR-STS) treated with neoadjuvant chemotherapy ± regional hyperthermia: EORTC 62961/ESHO-RHT 95 intergroup phase III study

Author

Lindner, L. H., primary, Schlemmer, M., additional, Hohenberger, P., additional, Wust, P., additional, Schmidt, M., additional, Verweij, J., additional, Judson, I., additional, Jauch, K. W., additional, Hiddemann, W., additional, and Issels, R. D., additional

Published
2005
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100. First interim report on the randomized EORTC 62961/ESHO-RHT 95 Intergroup Study (phase III) combined with regional hyperthermia (RHT) versus chemotherapy alone in the treatment of high-risk soft tissue sarcomas (HR-STS) in adults

Author

Lindner, L. H., primary, Schlemmer, M., additional, Hohenberger, P., additional, Wust, P., additional, Abdel-Rahman, S., additional, Schmidt, M., additional, Judson, I., additional, Blay, J. Y., additional, Verweij, J., additional, and Issels, R. D., additional

Published
2004
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