Search

Your search keyword '"Schmid, U."' showing total 1,343 results
Start Over Author "Schmid, U."
1,343 results on '"Schmid, U."'

100. A Telemedicine-Guided Self-Collection Approach for PCR-Based SARS-CoV-2 Testing: Comparative Study

Author

S. Würstle; J. Erber; M. Hanselmann; D. Hoffmann; S. Werfel; S. Hering; S. Weidlich; J. Schneider; R. Franke; M. Maier; A. G. Henkel; R. M. Schmid; U. Protzer; M. Laxy; C. D. Spinner and S. Würstle; J. Erber; M. Hanselmann; D. Hoffmann; S. Werfel; S. Hering; S. Weidlich; J. Schneider; R. Franke; M. Maier; A. G. Henkel; R. M. Schmid; U. Protzer; M. Laxy; C. D. Spinner

Abstract

Background: Large-scale, polymerase chain reaction (PCR)-based SARS-CoV-2 testing is expensive, resource intensive, and time consuming. A self-collection approach is a probable alternative; however, its feasibility, cost, and ability to prevent infections need to be evaluated. Objective: This study aims to compare an innovative self-collection approach with a regular SARS-CoV-2 testing strategy in a large European industrial manufacturing site. Methods: The feasibility of a telemedicine-guided PCR-based self-collection approach was assessed for 150 employees (intervention group) and compared with a regular SARS-CoV-2 testing approach used for 143 employees (control group). Acceptance, ergonomics, and efficacy were evaluated using a software application. A simulation model was implemented to evaluate the effectiveness. An interactive R shiny app was created to enable customized simulations. Results: The test results were successfully communicated to and interpreted without uncertainty by 76% (114/150) and 76.9% (110/143) of the participants in the intervention and control groups, respectively (P=.96). The ratings for acceptability, ergonomics, and efficacy among intervention group participants were noninferior when compared to those among control group participants (acceptability: 71.6% vs 37.6%; ergonomics: 88.1% vs 74.5%; efficacy: 86.4% vs 77.5%). The self-collection approach was found to be less time consuming (23 min vs 38 min; P<.001). The simulation model indicated that both testing approaches reduce the risk of infection, and the self-collection approach tends to be slightly less effective owing to its lower sensitivity. Conclusions: The self-collection approach for SARS-CoV-2 diagnosis was found to be technically feasible and well rated in terms of acceptance, ergonomics, and efficacy. The simulation model facilitates the evaluation of test effectiveness; nonetheless, considering context specificity, appropriate adaptation by companies is required. JMIR Form

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results