51. Assessment of HBV persistent infection in an adult population in Taiwan
- Author
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Hong-Wen Peng, Tsung-Sheng Su, King-Nien Ching, Chi-Kuan Ho, Chao-Hung Ho, Shou-Hwa Han, and Benjamin N. Chiang
- Subjects
Adult ,Male ,medicine.medical_specialty ,HBsAg ,Taiwan ,Semen ,Biology ,medicine.disease_cause ,Serology ,Hepatitis B Antigens ,Virology ,Epidemiology ,Blood plasma ,medicine ,Humans ,Hepatitis B virus ,virus diseases ,Middle Aged ,Hepatitis B ,Spermatozoa ,digestive system diseases ,Infectious Diseases ,Liver ,HBeAg ,Carrier State ,DNA, Viral ,Female ,Viral disease ,Epidemiologic Methods - Abstract
In order to study the prevalence of hepatitis B virus (HBV) in the adult population of Taiwan, we screened for the presence of HBV DNA in 205 blood samples from adult (20-59-year-old) volunteers. According to the serological markers of HBV, samples were divided into three groups: group I (173 subjects) was negative for both HBsAg and HBeAg; group II (14 subjects) was positive for both HBsAg and HBeAg; and group III consisted of 18 subjects who were HBsAg-positive but HBeAg-negative. Plasma HBV DNA was not detected in group I, but it was found in 85.7% and 11.8% of samples in group II and group III, respectively. A free-form HBV DNA was found in 14.3% of the leukocyte samples in group II. Furthermore, an integrated form of HBV DNA was detected in the leukocytes of two cases of group I who remained healthy based on clinical data. HBV DNA was also detected in the spermatozoa and liver cells of one of the cases. more...
- Published
- 1988
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