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55. This title is unavailable for guests, please login to see more information.

Author

González Soto, K. E. and González Soto, K. E.

Abstract

Cancer is one of the main causes of death and represents a worldwide health problem. Most of the cancer-related deaths are associated with the appearance and progression of a solid tumor. Even though effective conventional treatments exist, they share a common drawback, which is their incapacity to strictly distinguish between malignant and healthy cells. Since it was observed that immune cells are capable to eliminate cancer cells, extensive research has been made to retarget immune cells towards malignant cells without damaging healthy tissue. This type of approach is termed as immunotherapy and involves diverse strategies ranging from the use of Abs to engineered immune cells. One of the most attractive immunotherapeutic strategies is based on the engineering of T cells to express chimeric antigen receptors (CARs), which can recognize specific antigens localized on the surface of cancer cells, leading to an activation of the CAR T cells and a subsequently killing of the malignant cells. Even though CAR technology has shown a strong potential in targeting cancer cells during pre-clinical and clinical studies, numerous clinical trials have also revealed that once they are infused into the patient, the activity of the modified T cells becomes uncontrollable, which represents the main safety problem from the system. For this reason, a novel modular and switchable CAR platform, termed as RevCAR system, was developed in the group of Prof. Bachmann. A crucial element of mentioned system is the design of the RevCAR. In contrast to conventional CARs, RevCARs lack an extracellular binding moiety and comprise only a short peptide epitope instead. Thus, RevCAR T cells are per se inert because they cannot bind to any antigen. Only in the presence of target modules (RevTMs), which bind on the one hand to the peptide epitope of RevCARs and on the other hand simultaneously to tumor targets, RevCAR T cells can be redirected and consequently activated against tumor cells. An attra

Published
2019

56. Incorporation of Au and Ag nanostructures inside SiO2

Author

Fondo Nacional de Desarrollo Científico y Tecnológico (Chile), Consejo Superior de Investigaciones Científicas (España), Universidad de Zaragoza, Díaz, Carlos, Valenzuela, Maria Luisa, Soto, K., Laguna-Bercero, M. A., Fondo Nacional de Desarrollo Científico y Tecnológico (Chile), Consejo Superior de Investigaciones Científicas (España), Universidad de Zaragoza, Díaz, Carlos, Valenzuela, Maria Luisa, Soto, K., and Laguna-Bercero, M. A.

Abstract

Incorporation of Au° inside SiO2 was achieved by a solid-state method from the pyrolysis of the composites (Chitosan)•(AuCl3)n•(SiO2)m and (PS-co-4-PVP)•(AuCl3)n•(SiO2)m Similarly, the incorporation of Ag° inside SiO2 it was made from thermal treatment of the composites (Chitosan)•(AgNO3)n•(SiO2)m and (PS-co-4-PVP)•(AgNO3)n•(SiO2)m. The nature of the polymer controls the particle size for the Au/SiO2 composite, while that for the Ag/SiO2 both, polymer Chitosan and PS-co-4-PVP, produces similar particle size. In the case of the composite Ag/SiO2 the particle size as small as 5 nm were obtained.The 1:1 or 1:5 metal/polymer ratios, as well as the nature of the polymer in the macromolecular precursors (Chitosan)•(AuCl3)n•(SiO2)m and (PS-co-4-PVP)•(AuCl3)n•(SiO2)m influences the dispersion of the Au° nanostructures inside SiO2 matrix. The results are compared with those previously obtained for bimetallic composites Au/Ag//SiO2. A formation mechanism of the Au°/SiO2 and Ag°/SiO2 composites involving the combustion of the organic matter and the growth of the Au° and Ag° nanoparticles inside the holes, generated from the combustion process, is proposed.

Published
2019

57. MUSE GAS FLOW and WIND (MEGAFLOW). I. FIRST MUSE RESULTS on BACKGROUND QUASARS

Author

Schroetter, I, Bouche, N, Wendt, M, Contini, T, Finley, H, Pello, R, Bacon, R, Cantalupo, S, Marino, R, Richard, J, Lilly, S, Schaye, J, Soto, K, Steinmetz, M, Straka, L, Wisotzki, L, Schroetter I., Bouche N., Wendt M., Contini T., Finley H., Pello R., Bacon R., Cantalupo S., Marino R. A., Richard J., Lilly S. J., Schaye J., Soto K., Steinmetz M., Straka L. A., Wisotzki L., Schroetter, I, Bouche, N, Wendt, M, Contini, T, Finley, H, Pello, R, Bacon, R, Cantalupo, S, Marino, R, Richard, J, Lilly, S, Schaye, J, Soto, K, Steinmetz, M, Straka, L, Wisotzki, L, Schroetter I., Bouche N., Wendt M., Contini T., Finley H., Pello R., Bacon R., Cantalupo S., Marino R. A., Richard J., Lilly S. J., Schaye J., Soto K., Steinmetz M., Straka L. A., and Wisotzki L.

Abstract

The physical properties of galactic winds are one of the keys to understand galaxy formation and evolution. These properties can be constrained thanks to background quasar lines of sight (LOS) passing near star-forming galaxies (SFGs). We present the first results of the MusE GAs FLOw and Wind survey obtained from two quasar fields, which have eight Mg ii absorbers of which three have rest equivalent width greater than 0.8. With the new Multi Unit Spectroscopic Explorer (MUSE) spectrograph on the Very Large Telescope (VLT), we detect six (75%) Mg ii host galaxy candidates within a radius of 30′′ from the quasar LOS. Out of these six galaxy-quasar pairs, from geometrical argument, one is likely probing galactic outflows, where two are classified as "ambiguous," two are likely probing extended gaseous disks and one pair seems to be a merger. We focus on the wind-pair and constrain the outflow using a high-resolution quasar spectra from the Ultraviolet and Visual Echelle Spectrograph. Assuming the metal absorption to be due to ga;s flowing out of the detected galaxy through a cone along the minor axis, we find outflow velocities in the order of ≈150 (i.e., smaller than the escape velocity) with a loading factor, , of ≈0.7. We see evidence for an open conical flow, with a low-density inner core. In the future, MUSE will provide us with about 80 multiple galaxy-quasar pairs in two dozen fields.

Published
2016

60. Severe Systemic Lupus Erythematosus presentation in patient with alternative complement pathway mutations

Author

Pereira, F, Cunha, L, Campos, P, Gaspar, A, Manso, RT, and Soto, K

Subjects
Systemic lupus erythematosus, Acute kidney injury
Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease which can involve almost any organ, making its difficult therapeutic approach. Immune complex deposition can often activate complement, accounting for many of SLE clinical manifestations and laboratory findings. We present a case of a patient who presented with acute pancreatitis and acute kidney injury as onset manifestations of SLE, later developing neurological manifestations, who was successfully treated with rituximab, plasma exchange and steroids as induction therapy. Persistently low C3 level led to a genetic analysis of the complement system components. We found three polymorphisms in the alternative pathway of complement regulators (complement factor H c2669 G>T, p.Ser890Ile and c3019 G>T, p.Val1007Leu and complement factor I c.482+6 G>T), two of which have been correlated with atypical haemolytic uraemic syndrome and dense deposit disease and also complement factor H -related protein (CFHR1 and CFHR3) mutations by deletion. This raises the question whether these polymorphisms and mutations played any role in our patient’s clinical course. info:eu-repo/semantics/publishedVersion

Published
2017

61. POSSIBLE SIGNATURES OF A COLD-FLOW DISK FROM MUSE USING A z similar to 1 GALAXY-QUASAR PAIR TOWARD SDSS J1422-0001

Author

Bouche, N., Finley, H., Schroetter, I., Murphy, M. T., Richter, P., Bacon, R., Contini, T., Richard, J., Wendt, M., Kamann, S., Epinat, B., Cantalupo, S., Straka, L. A., Schaye, J., Martin, C. L., Peroux, C., Wisotzki, L., Soto, K., Lilly, S., Carollo, C. M., Brinchmann, J., Kollatschny, W., Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), and Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Aix Marseille Université (AMU)-Centre National d'Études Spatiales [Toulouse] (CNES)

Subjects
formation [galaxies], [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], Institut für Physik und Astronomie, intergalactic medium, Astrophysics::Cosmology and Extragalactic Astrophysics, individual (SDSS J142253.31-000149) [quasars], evolution [galaxies], Astrophysics::Galaxy Astrophysics
Abstract

International audience; We use a background quasar to detect the presence of circumgalactic gas around a z = 0.91 low-mass star-forming galaxy. Data from the new Multi Unit Spectroscopic Explorer (MUSE) on the Very Large Telescope show that the galaxy has a dust-corrected star formation rate (SFR) of 4.7 +/- 2.0. M-circle dot yr(-1), with no companion down to 0.22 M-circle dot yr(-1) (5 sigma) within 240 h(-1) kpc (”30”). Using a high-resolution spectrum of the background quasar, which is fortuitously aligned with the galaxy major axis (with an azimuth angle alpha of only 15 degrees), we find, in the gas kinematics traced by low-ionization lines, distinct signatures consistent with those expected for a “cold-flow disk” extending at least 12 kpc (3 x R-1/2). We estimate the mass accretion rate M-in to be at least two to three times larger than the SFR, using the geometric constraints from the IFU data and the H (I) column density of log N-H (I)/cm(-2) similar or equal to 20.4 obtained from a Hubble Space Telescope/COS near-UV spectrum. From a detailed analysis of the low-ionization lines (e.g., Zn II, Cr II, Ti II, MnII, Si II), the accreting material appears to be enriched to about 0.4 Z(circle dot) (albeit with large uncertainties: log Z/Z(circle dot) = -0.4 +/- 0.4), which is comparable to the galaxy metallicity (12 + log O/H = 8.7 +/- 0.2), implying a large recycling fraction from past outflows. Blueshifted Mg II and Fe II absorptions in the galaxy spectrum from the MUSE data reveal the presence of an outflow. The Mg II and Fe II absorption line ratios indicate emission infilling due to scattering processes, but the MUSE data do not show any signs of fluorescent Fe II* emission.

Published
2016
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64. INCORPORATION OF AU AND AG NANOSTRUCTURES INSIDE SIO2.

Author

DIAZ, C., VALENZUELA, A. M. L., SOTO, K., and LAGUNA-BERCERO, M. A.

Subjects
CHEMICAL elements, NANOSTRUCTURES, SOLID state chemistry, CHITOSAN, CHEMICAL precursors
Abstract

Incorporation of Au° inside SiO2 was achieved by a solid-state method from the pyrolysis of the composites (Chitosan)•(AuCl3)n•(SiO2)m and (PS-co-4-PVP)•(AuCl3)n•(SiO2)m Similarly, the incorporation of Ag° inside SiO2 it was made from thermal treatment of the composites (Chitosan)•(AgNO3)n•(SiO2)m and (PS-co-4-PVP)•(AgNO3)n•(SiO2)m. The nature of the polymer controls the particle size for the Au/SiO2 composite, while that for the Ag/SiO2 both, polymer Chitosan and PS-co-4-PVP, produces similar particle size. In the case of the composite Ag/SiO2 the particle size as small as 5 nm were obtained. The 1:1 or 1:5 metal/polymer ratios, as well as the nature of the polymer in the macromolecular precursors (Chitosan)•(AuCl3)n•(SiO2)m and (PS-co-4-PVP)•(AuCl3)n•(SiO2)m influences the dispersion of the Au° nanostructures inside SiO2 matrix. The results are compared with those previously obtained for bimetallic composites Au/Ag//SiO2. A formation mechanism of the Au°/SiO2 and Ag°/SiO2 composites involving the combustion of the organic matter and the growth of the Au° and Ag° nanoparticles inside the holes, generated from the combustion process, is proposed. [ABSTRACT FROM AUTHOR]

Published
2019
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65. MUSE GAS FLOW AND WIND (MEGAFLOW). I. FIRST MUSE RESULTS ON BACKGROUND QUASARS

Author

Schroetter, I., primary, Bouché, N., additional, Wendt, M., additional, Contini, T., additional, Finley, H., additional, Pelló, R., additional, Bacon, R., additional, Cantalupo, S., additional, Marino, R. A., additional, Richard, J., additional, Lilly, S. J., additional, Schaye, J., additional, Soto, K., additional, Steinmetz, M., additional, Straka, L. A., additional, and Wisotzki, L., additional

Published
2016
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66. MUSE observations of the lensing cluster Abell 1689

Author

Bina, D., primary, Pelló, R., additional, Richard, J., additional, Lewis, J., additional, Patrício, V., additional, Cantalupo, S., additional, Herenz, E. C., additional, Soto, K., additional, Weilbacher, P. M., additional, Bacon, R., additional, Vernet, J. D. R., additional, Wisotzki, L., additional, Clément, B., additional, Cuby, J. G., additional, Lagattuta, D. J., additional, Soucail, G., additional, and Verhamme, A., additional

Published
2016
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69. Presencia de exostosis orales en pacientes de la ciudad de Temuco, Chile

Author

Fuentes Fernández, R., Borie Echevarría, E., Sanhueza Campos, A., Rebolledo Soto, K., and Parra Villagran, P.

Subjects
Tori, anatomical condition, torus palatinus, torus palatino, torus mandibular, exostosis, torus mandibularis, Torus, condición anatómica, exostoses
Abstract

La palabra torus proviene del latín que significa tumor o protuberancia circular, el cual no es considerado una condición patológica. Se examinaron un total de 159 pacientes al azar en las clínicas odontológicas de la Universidad de La Frontera, Temuco para determinar la prevalencia de exostosis en la población. A estos pacientes se les aplicó una ficha clínica con el fin de relacionar esta condición con algunos posibles factores asociados. Se determinó una prevalencia de 5,66%, con predominio en el género femenino, en el sector mandibular. Si bien algunos factores estudiados mostraron ciertas tendencias ninguno, las características clínicas del torus mostró resultados estadísticamente significativos. The torus comes from Latin word that means circular prominence or tumor and which is not considered like a pathological condition. 159 patients were evaluated randomly in the dental clinics of Universidad de La Frontera, Temuco, to determine the prevalence of exostoses on this population. These patients filled a tab in order to relate this condition with some associated factors. A prevalence of 5.66% was observed with predominance in female gender, in mandibular zone. While certain factors studied showed no trends except for clinical features, none exhibited statistically significant results.

Published
2012

70. POSSIBLE SIGNATURES OF A COLD-FLOW DISK FROM MUSE USING Az∼ 1 GALAXY–QUASAR PAIR TOWARD SDSS J1422−0001

Author

Bouché, N., primary, Finley, H., additional, Schroetter, I., additional, Murphy, M. T., additional, Richter, P., additional, Bacon, R., additional, Contini, T., additional, Richard, J., additional, Wendt, M., additional, Kamann, S., additional, Epinat, B., additional, Cantalupo, S., additional, Straka, L. A., additional, Schaye, J., additional, Martin, C. L., additional, Péroux, C., additional, Wisotzki, L., additional, Soto, K., additional, Lilly, S., additional, Carollo, C. M., additional, Brinchmann, J., additional, and Kollatschny, W., additional

Published
2016
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72. Concentration of infectious pancreatic necrosis virus determined by combining tangential flow filtration with exclusion filtration

Author

Chamorro, C, Espinoza, J C, Soto, K, and Kuznar, J

Subjects
ultrafiltración, concentration, viruses, Virus IPN, ultrafiltration, IPN virus, concentración
Abstract

The infectious pancreatic necrosis virus, IPNV, is the etiological agent of a highly contagious disease that affects young salmon. The virus is mostly horizontally transmitted; therefore virus quantitation in water is mandatory for a proper sanitary management in the salmon industry as well as in the environment close to the hatcheries. To evaluate the water as a risk factor for IPNV infection in cultured or wild animals, it is necessary to titrate the virus with a suitable sensitivity. Therefore, a methodology that allows IPNV concentration to be determined in water using two kinds of ultrafiltration was developed. One, based on the tangential flow of the sample along the surface of a membrane, the other based on the retention of the viral particles at the surface of membranes with controlled pore diameter. Reagents and conditions were selected to reduce virus inactivation and/or virus binding to the filters. Finally, a protocol was developed that allows the concentration of IPNV in three orders of magnitude and with a total recovery of infectivity to be determined. This method can be performed in less than one day including virus titration using the fluorescent foci method., El virus de la necrosis pancreática infecciosa, virus IPN, es el agente causal de una enfermedad altamente contagiosa que afecta principalmente a peces jóvenes. El virus IPN se transmite mayoritariamente en forma horizontal, por lo cual la cuantificación del virus en el agua es fundamental para un adecuado manejo sanitario de la industria del salmón y del medio ambiente vecino a los sitios de cultivo. Con el fin de establecer el potencial riesgo del agua contaminada con virus IPN es necesario determinar la cantidad de virus activo mediante un procedimiento de detección con la adecuada sensibilidad para cuantificarlo en sus niveles de riesgo mínimos. Para contribuir a satisfacer esta necesidad es que se desarrolló una metodología que permite concentrar al virus desde el agua mediante la combinación de dos tipos de ultrafiltración. Uno basado en el flujo tangencial de la muestra por la superficie de una membrana concentradora y el otro basado en la retención de las partículas virales en la superficie de membranas de poro controlado. Se seleccionaron soluciones y condiciones de aplicación para minimizar la inactivación del virus y/o su unión a los filtros. Finalmente se establece un protocolo mediante el cual es posible concentrar mil veces al virus y con una recuperación total de la infectividad. La aplicación del método no tarda más de un día incluyendo la titulación del virus mediante la técnica de los focos fluorescentes.

Published
2006

74. The MUSE 3D view of theHubbleDeep Field South

Author

Bacon, R., primary, Brinchmann, J., additional, Richard, J., additional, Contini, T., additional, Drake, A., additional, Franx, M., additional, Tacchella, S., additional, Vernet, J., additional, Wisotzki, L., additional, Blaizot, J., additional, Bouché, N., additional, Bouwens, R., additional, Cantalupo, S., additional, Carollo, C. M., additional, Carton, D., additional, Caruana, J., additional, Clément, B., additional, Dreizler, S., additional, Epinat, B., additional, Guiderdoni, B., additional, Herenz, C., additional, Husser, T.-O., additional, Kamann, S., additional, Kerutt, J., additional, Kollatschny, W., additional, Krajnovic, D., additional, Lilly, S., additional, Martinsson, T., additional, Michel-Dansac, L., additional, Patricio, V., additional, Schaye, J., additional, Shirazi, M., additional, Soto, K., additional, Soucail, G., additional, Steinmetz, M., additional, Urrutia, T., additional, Weilbacher, P., additional, and de Zeeuw, T., additional

Published
2015
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75. CKD LAB METHODS, PROGRESSION & RISK FACTORS 2

Author

Onuigbo, M., primary, Agbasi, N., additional, Wu, M. J., additional, Shu, K. H., additional, Kugler, E., additional, Cohen, E., additional, Krause, I., additional, Goldberg, E., additional, Garty, M., additional, Jansen, J., additional, De Napoli, I. E., additional, Schophuizen, C. M., additional, Wilmer, M. J., additional, Mutsaers, H. A., additional, Heuvel, L. P., additional, Grijpma, D. W., additional, Stamatialis, D., additional, Hoenderop, J. G., additional, Masereeuw, R., additional, Van Craenenbroeck, A. H., additional, Van Craenenbroeck, E. M., additional, Van Ackeren, K., additional, Vrints, C. J., additional, Hoymans, V. Y., additional, Couttenye, M. M., additional, Erkmen Uyar, M., additional, Tutal, E., additional, Bal, Z., additional, Guliyev, O., additional, Sezer, S., additional, Liu, L., additional, Wang, C., additional, Tanaka, K., additional, Kushiyama, A., additional, Sakai, K., additional, Hara, S., additional, Ubara, Y., additional, Ohashi, Y., additional, Kunugi, Y., additional, Kawazu, S., additional, Untersteller, K., additional, Seiler, S., additional, Rogacev, K. S., additional, Emrich, I. E., additional, Lennartz, C. S., additional, Fliser, D., additional, Heine, G. H., additional, Hoshino, T., additional, Ookawara, S., additional, Miyazawa, H., additional, Ueda, Y., additional, Ito, K., additional, Kaku, Y., additional, Hirai, K., additional, Mori, H., additional, Yoshida, I., additional, Kakuta, S., additional, Hayama, N., additional, Amemiya, M., additional, Okamoto, H., additional, Inoue, S., additional, Tabei, K., additional, Campos, P., additional, Dias, C., additional, Baptista, J., additional, Papoila, A. L., additional, Ortiz, A., additional, Inchaustegui, L., additional, Soto, K., additional, Moon, K. H., additional, Yang, S., additional, Lee, D.-Y., additional, Kim, H. W., additional, Kim, B., additional, Isnard Bagnis, C., additional, Guerraoui, A., additional, Zenasni, F., additional, Idier, L., additional, Chauveau, P., additional, Cerqueira, A., additional, Quelhas-Santos, J., additional, Pestana, M., additional, Choi, J.-Y., additional, Jin, D.-C., additional, Choi, Y.-J., additional, Kim, W.-Y., additional, Nam, S.-A., additional, Cha, J.-H., additional, Cernaro, V., additional, Loddo, S., additional, Lacquaniti, A., additional, Romeo, A., additional, Costantino, G., additional, Montalto, G., additional, Santoro, D., additional, Trimboli, D., additional, Ricciardi, C. A., additional, Lacava, V., additional, Buemi, M., additional, Zawada, A. M., additional, Obeid, R., additional, Geisel, J., additional, Meneses, G. C., additional, Silva Junior, G., additional, Costa, M. F. B., additional, Goncalves, H. S., additional, Daher, E. F., additional, Liborio, A. B., additional, Martins, A. M. C., additional, Ekart, R., additional, Hojs, N., additional, Bevc, S., additional, Hojs, R., additional, Lim, C. S., additional, Hwang, J. H., additional, Chin, H. J., additional, Kim, S., additional, Kim, D. K., additional, Park, J. H., additional, Shin, S. J., additional, Lee, S. H., additional, Choi, B. S., additional, Lemoine, S., additional, Panaye, M., additional, Juillard, L., additional, Dubourg, L., additional, Hadj-Aissa, A., additional, Guebre-Egziabher, F., additional, Vieira, A. P. F., additional, Couto Bem, A. X., additional, Alves, M. P., additional, Stefan, G., additional, Capusa, C., additional, Stancu, S., additional, Margarit, D., additional, Petrescu, L., additional, Nedelcu, E. D., additional, Mircescu, G., additional, Szarejko-Paradowska, A., additional, Rysz, J., additional, Hung, C.-C., additional, Chen, H.-C., additional, Ristovska, V., additional, Grcevska, L., additional, Podesta, M. A., additional, Reggiani, F., additional, Cucchiari, D., additional, Badalamenti, S., additional, Ponticelli, C., additional, Graziani, G., additional, Nouri-Majalan, N., additional, Moghadasimousavi, S., additional, Eshaghyeh, Z., additional, Greenwood, S., additional, Koufaki, P., additional, Maclaughlin, H., additional, Rush, R., additional, Hendry, B. M., additional, Macdougall, I. C., additional, Mercer, T., additional, and Cairns, H., additional

Published
2014
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76. AKI - human studies

Author

Kutlay, S., primary, Kurultak, I., additional, Nergizoglu, G., additional, Erturk, S., additional, Karatan, O., additional, Azevedo, P., additional, Pinto, C. T., additional, Pereira, C. M., additional, Marinho, A., additional, Vanmassenhove, J., additional, Hoste, E., additional, Glorieux, G., additional, Dhondt, A., additional, Vanholder, R., additional, Van Biesen, W., additional, Rei, S., additional, Aleksandrova, I., additional, Kiselev, V., additional, Ilynskiy, M., additional, Berdnikov, G., additional, Marchenkova, L., additional, Daher, E. F., additional, Vieira, A. P. F., additional, Souza, J. B., additional, Falcao, F. S., additional, Costa, C. R., additional, Fernandes, A. A. C. S., additional, Mota, R. M. S., additional, Lima, R. S. A., additional, Silva Junior, G. B., additional, Ulusal Okyay, G., additional, Erten, Y., additional, Er, R., additional, Aybar, M., additional, Inal, S., additional, Tekbudak, M., additional, Aygencel, G., additional, Onec, K., additional, Bali, M., additional, Sindel, S., additional, Soto, K., additional, Fidalgo, P., additional, Papoila, A. L., additional, Lentini, P., additional, Zanoli, L., additional, Granata, A., additional, Contestabile, A., additional, Basso, A., additional, Berlingo, G., additional, de Cal, M., additional, Pellanda, V., additional, Dell'Aquila, R., additional, Fortrie, G., additional, Stads, S., additional, van Bommel, J., additional, Zietse, R., additional, Betjes, M. G., additional, Berrada, A., additional, Arias, C., additional, Riera, M., additional, Orfila, M. A., additional, Rodriguez, E., additional, Barrios, C., additional, Peruzzi, L., additional, Chiale, F., additional, Camilla, R., additional, Martano, C., additional, Cresi, F., additional, Bertino, E., additional, Coppo, R., additional, Klimenko, A., additional, Villevalde, S., additional, Efremovtseva, M., additional, Kobalava, Z., additional, Pipili, C., additional, Ioannidou, S., additional, Kokkoris, S., additional, Poulaki, S., additional, Tripodaki, E.-S., additional, Parisi, M., additional, Papastylianou, A., additional, Nanas, S., additional, Wang, Y.-n., additional, Cheng, H., additional, Chen, Y.-p., additional, Wen, Z., additional, Li, X., additional, Shen, P., additional, Zou, Y., additional, Lu, Y., additional, Ma, X., additional, Chen, Y., additional, Ren, H., additional, Chen, X., additional, Chen, N., additional, Yue, T., additional, Elmamoun, S., additional, Wodeyar, H., additional, Goldsmith, C., additional, Abraham, A., additional, Wootton, A., additional, Ahmed, S., additional, Hill, C., additional, Curtis, S., additional, Miller, A., additional, Hine, T., additional, Stevens, K. K., additional, Patel, R. K., additional, Mark, P. B., additional, Delles, C., additional, Jardine, A. G., additional, Wilflingseder, J., additional, Heinzel, A., additional, Mayer, P., additional, Perco, P., additional, Kainz, A., additional, Mayer, B., additional, Oberbauer, R., additional, Huang, T.-M., additional, Wu, V.-C., additional, Park, D. J., additional, Bae, E. J., additional, Kang, Y.-J., additional, Cho, H. S., additional, Chang, S.-h., additional, Stramana, R., additional, Cognolato, D., additional, Baiocchi, M., additional, Chiella, B. M., additional, Pilla, C., additional, Balbinotto, A., additional, Antunes, V. H., additional, Heglert, A., additional, Collares, F. M., additional, Thome, F. S., additional, Gjyzari, A., additional, Thereska, N., additional, Xhango, O., additional, Xue, J., additional, Chen, M. C., additional, Wang, L., additional, Chen, Y. J., additional, Sun, X. Z., additional, An, W. S., additional, Kim, E. S., additional, Son, Y. K., additional, Kim, S. E., additional, Kim, K. H., additional, Oh, Y. J., additional, Tsai, H.-B., additional, Ko, W.-J., additional, Chao, C.-T., additional, Aarnoudse, A.-J. L., additional, Peride, I., additional, Radulescu, D., additional, Niculae, A., additional, Ciocalteu, A., additional, Checherita, A.-I., additional, Kao, C.-C., additional, Wang, C.-Y., additional, Lai, C.-F., additional, Chen, H.-H., additional, Wu, K.-D., additional, Klaus, F., additional, Goldani, J. C., additional, Cantisani, G., additional, Zanotelli, M. L., additional, Carvalho, L., additional, Klaus, D., additional, Garcia, V. D., additional, Keitel, E., additional, Hussaini, S. M., additional, Rao, P. N., additional, Kul, A., additional, Ye, N., additional, Zhang, Y., additional, Baines, R., additional, Westacott, R., additional, Trew, J., additional, Kirtley, J., additional, Selby, N., additional, Carr, S., additional, Xu, G., additional, Steffgen, J., additional, Blaschke, S., additional, Brun-Schulte-Wissing, N., additional, Pagel, P., additional, Huber, F., additional, Mapes, J., additional, Jaehnige, A., additional, Pestel, S., additional, Deray, G., additional, Rouviere, O., additional, Bacigalupo, L., additional, Maes, B., additional, Hannedouche, T., additional, Vrtovsnik, F., additional, Rigothier, C., additional, Billiouw, J.-M., additional, Campioni, P., additional, Marti-Bonmati, L., additional, Gao, Y.-m., additional, Li, D., additional, Woo, S., additional, Lee, J., additional, Noh, H., additional, Kwon, S. H., additional, Han, D. C., additional, Hetherington, L., additional, Valluri, A., additional, McQuarrie, E., additional, Fleming, S., additional, Geddes, C., additional, Bell, S., additional, MacKinnon, B., additional, Patton, A., additional, Sneddon, J., additional, Donnan, P., additional, Vadiveloo, T., additional, Marwick, C., additional, Bennie, M., additional, Davey, P., additional, Yasuda, H., additional, Tsuji, N., additional, Tsuji, T., additional, Iwakura, T., additional, Ohashi, N., additional, Kato, A., additional, Fujigaki, Y., additional, Sasaki, S., additional, Kawarazaki, H., additional, Shibagaki, Y., additional, Kimura, K., additional, Lingaraju, U., additional, Rajanna, S., additional, Radhakrishnan, H., additional, Parekh, A., additional, Sreedhar, C. G., additional, Sarvi, R., additional, Rainone, F., additional, Merlino, L., additional, Ritchie, J. P., additional, Kalra, P. A., additional, Jacinto, C. N., additional, Abreu, K. L. S., additional, Neves, M., additional, Baptista, J. P., additional, Rodrigues, L., additional, Pinho, J., additional, Teixeira, L., additional, Pimentel, J., additional, Gonzalez Sanchidrian, S., additional, Rangel Hidalgo, G., additional, Cebrian Andrada, C., additional, Deira Lorenzo, J., additional, Marin Alvarez, J., additional, Garcia-Bernalt Funes, V., additional, Gallego Dominguez, S., additional, Labrador Gomez, P., additional, Castellano Cervino, I., additional, Novillo Santana, R., additional, Gomez-Martino Arroyo, J., additional, Kim, Y., additional, Choi, B. S., additional, Kim, Y. o., additional, Yoon, S. A., additional, Lin, M.-C., additional, Wang, W.-J., additional, Melo, M. J., additional, Lopes, J. A., additional, Raimundo, M., additional, Fragoso, A., additional, Antunes, F., additional, Martin-Moreno, P. L., additional, Varo, N., additional, Restituto, P., additional, Sayon-Orea, C., additional, Garcia-Fernandez, N., additional, Leite Filho, N. C. V., additional, Souza, L. E. O., additional, Cavalcante, R. M., additional, Morais, B. M., additional, Leite, T. T., additional, Silva, S. L., additional, Kubrusly, M., additional, Jung, Y. S., additional, Kim, Y. N., additional, Shin, H. S., additional, Rim, H., additional, Bentall, A., additional, Al-Baaj, F., additional, Williamson, S., additional, Cheshire, S., additional, Jelakovic, M., additional, Ivkovic, V., additional, Laganovic, M., additional, Karanovic, S., additional, Pecin, I., additional, Premuzic, V., additional, Vukovic Lela, I., additional, Vrdoljak, A., additional, Fucek, M., additional, Cvitkovic, A., additional, Juric, D., additional, Bozina, N., additional, Bitunjac, M., additional, Leko, N., additional, Abramovic Baric, M., additional, Matijevic, V., additional, Jelakovic, B., additional, Ullah, A., additional, Exarchou, K., additional, Archer, T., additional, Anijeet, H., additional, Brown, R., additional, Cheng, Y.-p., additional, Rocha, J. C. G., additional, Gushiken da Silva, T., additional, de Castro, P. F., additional, Kioroglo, P. S., additional, Branco Martins, J. P., additional, Tzanno-Martins, C., additional, Biesenbach, P., additional, Luf, F., additional, Fleischmann, E., additional, Grunberger, T., additional, Druml, W., additional, Gaipov, A., additional, Turkmen, K., additional, Toker, A., additional, Solak, Y., additional, Cicekler, H., additional, Ucar, R., additional, Kilicaslan, A., additional, Gormus, N., additional, Tonbul, H. Z., additional, Yeksan, M., additional, Turk, S., additional, Monteburini, T., additional, Cenerelli, S., additional, Santarelli, S., additional, Boggi, R., additional, Tazza, L., additional, Bossola, M., additional, Ferraresi, M., additional, Merlo, I., additional, Giovinazzo, G., additional, Quercia, A. D., additional, Gai, M., additional, Leonardi, G., additional, Anania, P., additional, Guarena, C., additional, Cantaluppi, V., additional, Pacitti, A., additional, Biancone, L., additional, Hissa, P. N. G., additional, Daher, E. D. F., additional, Liborio, A. B., additional, Thereza, B. M. F., additional, Mendes, C. C. P., additional, and Sousa, A. R. O., additional

Published
2013
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82. Acute kidney injury - Human studies

Author

Locsey, L., primary, Seres, I., additional, Sztanek, F., additional, Harangi, M., additional, Padra, J., additional, Asztalos, L., additional, Paragh, G., additional, Hutchison, C. A., additional, Bevins, A., additional, Langham, R., additional, Mancini, E., additional, Wirta, O., additional, Cockwell, P., additional, Keir, R., additional, Vigano, M., additional, Stella, A., additional, Evans, N., additional, Chappell, M., additional, Fabbrini, P., additional, Onuigbo, M., additional, Onuigbo, N., additional, Kim, S., additional, Chang, J. H., additional, Jung, J. Y., additional, Lee, H. H., additional, Chung, W., additional, Zanoli, L., additional, Rastelli, S., additional, Marcantoni, C., additional, Tamburino, C., additional, Castellino, P., additional, Cho, A., additional, Choi, H., additional, Lee, J. E., additional, Jang, H. R., additional, Huh, W., additional, Kim, Y.-G., additional, Kim, D. J., additional, Oh, H. Y., additional, Garcia-Fernandez, N., additional, Martin-Moreno, P. L., additional, Varo, N., additional, Nunez-Cordoba, J. M., additional, Schlieper, G., additional, Kruger, T., additional, Kelm, M., additional, Floege, J., additional, Westenfeld, R., additional, Cho, A. J., additional, Doganay, S., additional, Oguz, A. K., additional, Ergun, I., additional, Bardachenko, N., additional, Kuryata, O., additional, Bardachenko, L., additional, Ravani, P., additional, Malberti, F., additional, Pirelli, S., additional, Scolari, F., additional, Barrett, B., additional, Presta, P., additional, Lucisano, G., additional, Rubino, A., additional, Serraino, F., additional, Amoruso, T., additional, Renzulli, A., additional, Fuiano, G., additional, Kielstein, J. T., additional, Tolk, S., additional, Heiden, A., additional, Kuhn, C., additional, Hoeper, M. M., additional, Lorenzen, J., additional, Broll, M., additional, Kaever, V., additional, Burhenne, H., additional, Hafer, C., additional, Haller, H., additional, Burkhardt, O., additional, Kielstein, J., additional, Zahalkova, J., additional, Petejova, N., additional, Strojil, J., additional, Urbanek, K., additional, Bertoli, S., additional, Musetti, C., additional, Cabiati, A., additional, Assanelli, E., additional, Lauri, G., additional, Marana, I., additional, De Metrio, M., additional, Rubino, M., additional, Campodonico, J., additional, Grazi, M., additional, Moltrasio, M., additional, Marenzi, G., additional, Unarokov, Z., additional, Mukhoedova, T., additional, Fidalgo, P., additional, Coelho, S., additional, Rodrigues, B., additional, Fernandes, A. P., additional, Papoila, A. L., additional, Liano, F., additional, Soto, K., additional, Vanmassenhove, J., additional, Vanholder, R., additional, Glorieux, G., additional, Van Biesen, W., additional, Challiner, R., additional, Ritchie, J., additional, Hutchison, A., additional, Zaharie, S. I., additional, Maria, D. T., additional, Zaharie, M., additional, Vaduva, C., additional, Grauntanu, C., additional, Cana-Ruiu, D., additional, Mota, E., additional, Hayer, M., additional, Baharani, J., additional, Thomas, M., additional, Eldehni, T., additional, Selby, N., additional, McIntyre, C., additional, Fluck, R., additional, Kolhe, N., additional, Fagugli, R. M., additional, Patera, F., additional, Shah, P. R., additional, Kaswan, K. K., additional, Kute, V. B., additional, Vanikar, A. V., additional, Gumber, M. R., additional, Patel, H. V., additional, Munjappa, B. C., additional, Enginner, D. P., additional, Sainaresh, V. V., additional, Trivedi, H. L., additional, Teixeira, C., additional, Nogueira, E., additional, Lopes, J. A., additional, Almeida, E., additional, Pais de Lacerda, A., additional, Gomes da Costa, A., additional, Franca, C., additional, Mariano, F., additional, Morselli, M., additional, Bergamo, D., additional, Hollo', Z., additional, Scella, S., additional, Maio, M., additional, Tetta, C., additional, Dellavalle, A., additional, Stella, M., additional, Triolo, G., additional, Cantaluppi, V., additional, Quercia, A. D., additional, Bertinetto, P., additional, Giacalone, S., additional, Tamagnone, M., additional, Basso, E., additional, Karvela, E., additional, Gai, M., additional, Leonardi, G., additional, Anania, P., additional, Guarena, C., additional, Fenocchio, C. M., additional, Pacitti, A., additional, Segoloni, G. P., additional, Kim, Y. O., additional, Kim, H. G., additional, Kim, B. S., additional, Song, H. C. S., additional, Min, J.-K., additional, Kim, S. Y., additional, Park, W. D., additional, Dalboni, M., additional, Narciso, R., additional, Quinto, M., additional, Grabulosa, C., additional, Cruz, E., additional, Monte, J., additional, Durao, M., additional, Cendoroglo, M., additional, Santos, O., additional, Batista, M., additional, Bellasi, A., additional, Giannone, S., additional, Mordenti, A., additional, Zanoni, A., additional, Santoro, A., additional, Lee, J. H., additional, Ha, S. H., additional, Kim, J. H., additional, Lee, G. J., additional, Jung, Y. C., additional, Malindretos, P., additional, Koutroumbas, G., additional, Patrinou, A., additional, Zagkotsis, G., additional, Makri, P., additional, Togousidis, I., additional, Syrganis, C., additional, Li Cavoli, G., additional, Tortorici, C., additional, Bono, L., additional, Ferrantelli, A., additional, Giammarresi, C., additional, Zagarrigo, C., additional, Rotolo, U., additional, Kim, H., additional, Jun, K., additional, Choi, W., additional, Krzesinski, J.-M., additional, Parotte, M.-C., additional, Vandevelde, C., additional, Keenan, J., additional, Dieterle, F., additional, Sultana, S., additional, Pinches, M., additional, Ciorciaro, C., additional, Schindler, R., additional, Schmitz, V., additional, Gautier, J.-C., additional, Benain, X., additional, Matchem, J., additional, Murray, P., additional, Adler, S., additional, Haase, M., additional, Haase-Fielitz, A., additional, Devarajan, P., additional, Bellomo, R., additional, Cruz, D. N., additional, Wagener, G., additional, Krawczeski, C. D., additional, Koyner, J. L., additional, Murray, P. T., additional, Zappitelli, M., additional, Goldstein, S., additional, Makris, K., additional, Ronco, C., additional, Martensson, J., additional, Martling, C.-R., additional, Venge, P., additional, Siew, E., additional, Ware, L. B., additional, Ikizler, A., additional, Mertens, P. R., additional, Lacquaniti, A., additional, Buemi, A., additional, Donato, V., additional, Lucisano, S., additional, Buemi, M., additional, Panagoutsos, S., additional, Kriki, P., additional, Mourvati, E., additional, Tziakas, D., additional, Chalikias, G., additional, Stakos, D., additional, Apostolakis, S., additional, Tsigalou, C., additional, Gioka, T., additional, Konstantinides, S., additional, Vargemezis, V., additional, Torregrosa, I., additional, Montoliu, C., additional, Urios, A., additional, Aguado, C., additional, Puchades, M. J., additional, Solis, M. A., additional, Juan, I., additional, Sanjuan, R., additional, Blasco, M., additional, Pineda, J., additional, Carratala, A., additional, Ramos, C., additional, Miguel, A., additional, Niculae, A., additional, Checherita, I. A., additional, Sandulovici, R., additional, David, C., additional, Ciocalteu, A., additional, Espinoza, M., additional, Hidalgo, J., additional, Lorca, E., additional, Santibanez, A., additional, Arancibia, F., additional, Gonzalez, F., additional, Park, M. Y., additional, Kim, E. J., additional, Choi, S. J., additional, Kim, J. K., additional, Hwang, S. D., additional, Lee, K.-h., additional, Seok, S.-J., additional, Yang, J.-O., additional, Lee, E.-Y., additional, Hong, S.-y., additional, Gil, H.-w., additional, Astapenko, E., additional, Shutov, A., additional, Savinova, G., additional, Rechnik, V., additional, Melo, M. J., additional, Raimundo, M., additional, Viegas, A., additional, Camara, I., additional, Antunes, F., additional, Kim, M.-J., additional, Kwon, S. H., additional, Lee, S. W., additional, Song, J. H., additional, and Lee, J. W., additional

Published
2011
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94. Evaluation of a real-time passive personal particle monitor in fixed site residential indoor and ambient measurements.

Author

QUINTANA, PENELOPE J E, SAMIMI, BEHZAD S, KLEINMAN, MICHAEL T, LIU, L-J, SOTO, K E L V I N, WARNER, GREGORY Y, BUFALINO, C H A R L E S, VALENCIA, J E S U S, FRANCIS, D I A N E, HOVELL, MELBOURNE H, and DELFINO, RALPH J

Subjects
AIR pollution, ENVIRONMENTAL exposure, LIGHT scattering, ENVIRONMENTAL sciences
Abstract

Recent experimental findings in animals and humans indicate adverse respiratory effects from short-term exposures to particulate air pollutants, especially in sensitive subpopulations such as asthmatics. The relationship between air pollution and asthma has mainly been determined using particulate matter (PM) measurements from central sites. Validated tools are needed to assess exposures most relevant to health effects. Recently; a personal passive particulate sampler (personal Data-RAM, pDR, MIE Inc., Bedford, MA) has become available for studying personal exposures to PM with time resolution at 1 min. The pDR measures light scatter from PM in the 0.1-10 μM range, the significant range for health effects. In order to assess the ability of the pDR in predicting gravimetric mass, pDRs were collocated with PM[SUB2.5] and PM[SUB10] Harvard Impactors (HI) inside and outside nine homes of asthmatic children and at an outdoor central Air Pollution Control District site. Results are presented of comparisons between the HI samplers and the pDR in various modes of operation: passive, active, and active with a heated inlet. When used outdoors at fixed sites the pDR readings exhibit interference from high relative humidity (RH) unless operated with a method for drying inlet air such as a heater, or if readings at times of high RH are adjusted. The pDR correlates more highly with the HI PM[SUB2.5] than with the HI PM[SUB10] (r[SUP2]=0.66 vs. 0.13 for outdoors, r[SUP2] = 0.42 vs. 0.20 for indoors). The pDR appears to be a useful tool for an epidemiologic study that aims to examine the relationship between health outcomes and personal exposure to peaks in PM. [ABSTRACT FROM AUTHOR]

Published
2000
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95. Readdressing Personal Cooling With Ice

Author

Kamon, E., Kenney, W. L., Deno, N. S., Soto, K. I., and Carpenter, A. J.

Abstract

An ice-based system of personal, non-restrictive cooling of workers exposed to high temperature work environments in nuclear power plants was evaluated. The garments were designed to be worn under the protective clothing donned for penetration into radiation areas. The cooling system consisted of direct body contact with small packets of frozen water enclosed in the pockets of a shirt in high ambient temperatures (55°C) and moderate metabolic heat production (200-300 kcal/hr). Mean exposure time without cooling (control) was 52 min for workloads demanding 200 kcal/hr energy expenditure. A long garment with 7.2 kg of frozen water (LFWG) increased mean exposure time over the control by 242% (163% for the same garment with 6.2 kg of frozen water). A short version garment with 3.8 kg of frozen water (SFWG) increased the stay time by 115%. In field observations, the LFWG with 6.2 kg of frozen water improved stay time by 125%. The leveling off of the body temperatures and heart rates during the work both in the laboratory and in the field confirmed a reduction of heat strain associated with the use of these garments. Calculated heat balance equations of heat uptake by the ice predicted these results very closely. It was concluded that direct body contact with frozen water provided predictable adequate body cooling for the work and ambient conditions investigated in this study.

Published
1986
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96. MUSE Commissioning

Author

Bacon, R., Joël Vernet, Borisova, E., Bouché, N., Brinchmann, J., Carollo, M., Carton, D., Caruana, J., Cerda, S., Contini, T., Franx, M., Girard, M., Guerou, A., Haddad, N., Hau, G., Herenz, C., Herrera, J. C., Husemann, B., Husser, T. -O, Jarno, A., Kamann, S., Krajnovic, D., Lilly, S., Mainieri, V., Martinsson, T., Palsa, R., Patricio, V., Pécontal, A., Pello, R., Piqueras, L., Richard, J., Sandin, C., Schroetter, I., Selman, F., Shirazi, M., Smette, A., Soto, K., Streicher, O., Urrutia, T., Weilbacher, P., Wisotzki, L., and Zins, G.

98. VizieR Online Data Catalog: MUSE 3D view of HDF-S (Bacon+, 2015)

Author

Bacon, R., Brinchmann, J., Richard, J., Contini, T., Drake, A., Franx, M., Tacchella, S., Joël Vernet, Wisotzki, L., Blaizot, J., Bouche, N., Bouwens, R., Cantalupo, S., Carollo, C. M., Carton, D., Caruana, J., Clement, B., Dreizler, S., Epinat, B., Guiderdoni, B., Herenz, C., Husser, T. -O, Kamann, S., Kerutt, J., Kollatschny, W., Krajnovic, D., Lilly, S., Martinsson, T., Michel-Dansac, L., Patricio, V., Schaye, J., Shirazi, M., Soto, K., Soucail, G., Steinmetz, M., Urrutia, T., Weilbacher, P., and Zeeuw, T.

99. Evaluation of interstitial lesions in well-functioning renal allografts

Author

Serón D, Francesc Moreso, Condom E, Carrera M, Cañas C, Jm, Cruzado, Soto K, Gil-Vernet S, Torras J, and Am, Castelao

Subjects
Adult, Male, Analysis of Variance, Biopsy, Creatinine, Humans, Transplantation, Homologous, Female, Kidney Transplantation, Follow-Up Studies, Glomerular Filtration Rate, Retrospective Studies

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