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51. Prognostic value of total tumor volume in patients with colorectal liver metastases: A secondary analysis of the randomized CAIRO5 trial with external cohort validation

Author

Hart- en Vaatziekten Team A, Epi Kanker Team B, Cancer, MS CGO, Zorgeenheid Kinderchirurgie Medisch, Researchgr. Beeldg. Moleculaire Interv., Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, Kazemier, Geert, Hart- en Vaatziekten Team A, Epi Kanker Team B, Cancer, MS CGO, Zorgeenheid Kinderchirurgie Medisch, Researchgr. Beeldg. Moleculaire Interv., Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, and Kazemier, Geert

Published
2024

52. Prognostic value of total tumor volume in patients with colorectal liver metastases:A secondary analysis of the randomized CAIRO5 trial with external cohort validation

Author

Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, Kazemier, Geert, Michiel Zeeuw, J., Wesdorp, Nina J., Ali, Mahsoem, Bakker, Anne Joëlle J.J., Voigt, Kelly R., Starmans, Martijn P.A., Roor, Joran, Kemna, Ruby, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M.G.C., Moos, Shira I., van Dieren, Susan, van Amerongen, Martinus J., Bond, Marinde J.G., Chapelle, Thiery, van Dam, Ronald M., Engelbrecht, Marc R.W., Gerhards, Michael F., van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Kok, Niels F.M., Leclercq, Wouter K.G., Liem, Mike S.L., van Lienden, Krijn P., Quintus Molenaar, I., Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., de Wilt, Johannes H.W., Verpalen, Inez M., Stoker, Jaap, Grunhagen, Dirk J., Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Verhoef, Cornelis, and Kazemier, Geert

Abstract

Background:This study aimed to assess the prognostic value of total tumor volume (TTV) for early recurrence (within 6 months) and overall survival (OS) in patients with colorectal liver metastases (CRLM), treated with induction systemic therapy followed by complete local treatment.Methods: Patients with initially unresectable CRLM from the multicenter randomized phase 3 CAIRO5 trial (NCT02162563) who received induction systemic therapy followed by local treatment were included. Baseline TTV and change in TTV as response to systemic therapy were calculated using the CT scan before and the first after systemic treatment, and were assessed for their added prognostic value. The findings were validated in an external cohort of patients treated at a tertiary center. Results:In total, 215 CAIRO5 patients were included. Baseline TTV and absolute change in TTV were significantly associated with early recurrence (P = 0.005 and P = 0.040, respectively) and OS in multivariable analyses (P = 0.024 and P = 0.006, respectively), whereas RECIST1.1 was not prognostic for early recurrence (P = 0.88) and OS (P = 0.35). In the validation cohort (n = 85), baseline TTV and absolute change in TTV remained prognostic for early recurrence (P = 0.041 and P = 0.021, respectively) and OS in multivariable analyses (P < 0.0001 and P = 0.012, respectively), and showed added prognostic value over conventional clinicopathological variables (increase C-statistic, 0.06; 95 % CI, 0.02 to 0.14; P = 0.008). Conclusion: Total tumor volume is strongly prognostic for early recurrence and OS in patients who underwent complete local treatment of initially unresectable CRLM, both in the CAIRO5 trial and the validation cohort. In contrast, RECIST1.1 did not show prognostic value for neither early recurrence nor OS.

Published
2024

53. Optimizing pseudo-spiral sampling for abdominal DCE MRI using a digital anthropomorphic phantom

Author

Cancer, Computational Imaging, MS Radiologie, Wassenaar, Nienke P.M., Gurney-Champion, Oliver J., van Schelt, Anne Sophie, Bruijnen, Tom, van Laarhoven, Hanneke W.M., Stoker, Jaap, Nederveen, Aart J., Runge, Jurgen H., Schrauben, Eric M., Cancer, Computational Imaging, MS Radiologie, Wassenaar, Nienke P.M., Gurney-Champion, Oliver J., van Schelt, Anne Sophie, Bruijnen, Tom, van Laarhoven, Hanneke W.M., Stoker, Jaap, Nederveen, Aart J., Runge, Jurgen H., and Schrauben, Eric M.

Published
2024

57. Cumulative 5-year Results of a Randomized Controlled Trial Comparing Biological Mesh With Primary Perineal Wound Closure After Extralevator Abdominoperineal Resection (BIOPEX-study)

Author

Blok, Robin D., Sharabiany, Sarah, Stoker, Jaap, Laan, Ellen T. M., Bosker, Robbert J. I., Burger, Jacobus W. A., Chaudhri, Sanjay, van Duijvendijk, Peter, van Etten, Boudewijn, van Geloven, Anna A. W., de Graaf, Eelco J. R., Hoff, Christiaan, Hompes, Roel, Leijtens, Jeroen W. A., Rothbarth, Joost, Rutten, Harm J. T., Singh, Baljit, Vuylsteke, Ronald J. C. L. M., de Wilt, Johannes H. W., Dijkgraaf, Marcel G. W., Bemelman, Willem A., Musters, Gijsbert D., and Tanis, Pieter J.

Published
2022
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59. Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment

Author

Geffen, Eline G.M. van, primary, Nederend, Joost, additional, Sluckin, Tania C., additional, Hazen, Sanne-Marije J.A., additional, Horsthuis, Karin, additional, Beets-Tan, Regina G.H., additional, Marijnen, Corrie A.M., additional, Tanis, Pieter J., additional, Kusters, Miranda, additional, Aalbers, Arend G.J., additional, van Aalten, Susanna M., additional, Amelung, Femke J., additional, Ankersmit, Marjolein, additional, Antonisse, Imogeen E., additional, Ashruf, Jesse F., additional, Aukema, Tjeerd S., additional, Avenarius, Henk, additional, Bahadoer, Renu R., additional, Bakers, Frans C.H., additional, Bakker, Ilsalien S., additional, Bangert, Fleur, additional, Barendse, Renée M., additional, Beekhuis, Heleen M.D., additional, Beets, Geerard L., additional, Bemelman, Willem A., additional, Berbée, Maaike, additional, de Bie, Shira H., additional, Bisschops, Robert H.C., additional, Blok, Robin D., additional, van Bockel, Liselotte W., additional, Boer, Anniek H., additional, den Boer, Frank C., additional, Boerma, Evert-Jan G., additional, Boogerd, Leonora S.F., additional, Borstlap, Jaap, additional, Borstlap, Wernard A.A., additional, Bouwman, Johanna E., additional, Braak, Sicco J., additional, Braat, Manon N.G.J.A., additional, Bradshaw, Jennifer, additional, Brandsma, Amarins T.A., additional, van Breest Smallenburg, Vivian, additional, van den Broek, Wim T., additional, van der Burg, Sjirk W., additional, Burger, Jacobus W.A., additional, Burghgraef, Thijs A., additional, ten Cate, David W.G., additional, Ceha, Heleen M., additional, Cnossen, Jeltsje S., additional, Coebergh van den Braak, Robert R.J., additional, Consten, Esther C.J., additional, Corver, Maaike, additional, Crolla, Rogier M.P.H., additional, Curutchet, Sam, additional, Daniëls-Gooszen, Alette W., additional, Davids, Paul H.P., additional, Dekker, Emmelie N., additional, Dekker, Jan Willem T., additional, Demirkiran, Ahmet, additional, Derksen, Tyche, additional, Diederik, Arjen L., additional, Dinaux, Anne M., additional, Dogan, Kemal, additional, van Dop, Ilse M., additional, Droogh-de Greve, Kitty E., additional, Duijsens, Hanneke M.H., additional, Dunker, Michalda S., additional, Duyck, Johan, additional, van Duyn, Eino B., additional, van Egdom, Laurentine S.E., additional, Eijlers, Bram, additional, El-Massoudi, Youssef, additional, van Elderen, Saskia, additional, Emmen, Anouk M.L.H., additional, Engelbrecht, Marc, additional, van Erp, Anne C., additional, van Essen, Jeroen A., additional, Fabry, Hans F.J., additional, Fassaert, Thomas, additional, Feitsma, Eline A., additional, Feshtali, Shirin S., additional, Frietman, Bas, additional, Furnée, Edgar J.B., additional, van Geel, Anne M., additional, Geijsen, Elisabeth D., additional, van Geloven, Anna A.W., additional, Gerhards, Michael F., additional, Gielkens, Hugo, additional, van Gils, Renza A.H., additional, Goense, Lucas, additional, Govaert, Marc J.P.M., additional, van Grevenstein, Wilhelmina M.U., additional, Joline de Groof, E., additional, de Groot, Irene, additional, de Haas, Robbert J., additional, Hakkenbrak, Nadia A.G., additional, den Hartogh, Mariska D., additional, Heesink, Vera, additional, Heikens, Joost T., additional, Hendriksen, Ellen M., additional, van den Hoek, Sjoerd, additional, van der Hoeven, Erik J.R.J., additional, Hoff, Christiaan, additional, Hogewoning, Anna, additional, Hogewoning, Cornelis R.C., additional, Hoogendoorn, Stefan, additional, van Hoorn, Francois, additional, van der Hul, René L., additional, van Hulst, Rieke, additional, Imani, Farshad, additional, Inberg, Bas, additional, Intven, Martijn P.W., additional, Janssen, Pedro, additional, de Jong, Chris E.J., additional, Jonkers, Jacoline, additional, Jou-Valencia, Daniela, additional, Keizers, Bas, additional, Ketelaers, Stijn H.J., additional, Knöps, Eva, additional, van Koeverden, Sebastiaan, additional, Kok, Sylvia, additional, Kolderman, Stephanie E.M., additional, de Korte, Fleur I., additional, Kortekaas, Robert T.J., additional, Korving, Julie C., additional, Koster, Ingrid M., additional, Krdzalic, Jasenko, additional, Krielen, Pepijn, additional, Kroese, Leonard F., additional, Krul, Eveline J.T., additional, Lahuis, Derk H.H., additional, Lamme, Bas, additional, van Landeghem, An A.G., additional, Leijtens, Jeroen W.A., additional, Leseman-Hoogenboom, Mathilde M., additional, de Lijster, Manou S., additional, Marsman, Martijn S., additional, Martens, MilouH., additional, Masselink, Ilse, additional, van der Meij, Wout, additional, Meijnen, Philip, additional, Melenhorst, Jarno, additional, de Mey, Dietrich J.L., additional, Moelker-Galuzina, Julia, additional, Morsink, Linda, additional, Mulder, Erik J., additional, Muller, Karin, additional, Musters, Gijsbert D., additional, Neijenhuis, Peter A., additional, de Nes, Lindsey C.F., additional, Nielen, M., additional, van den Nieuwboer, Jan B.J., additional, Nieuwenhuis, Jonanne F., additional, Nonner, Joost, additional, Noordman, Bo J., additional, Nordkamp, Stefi, additional, Olthof, Pim B., additional, Oosterling, Steven J., additional, Ootes, Daan, additional, Oppedijk, Vera, additional, Ott, Pieter, additional, Paulusma, Ida, additional, Peeters, Koen C.M.J., additional, Pereboom, Ilona T.A., additional, Peringa, Jan, additional, Pironet, Zoë, additional, Plate, Joost D.J., additional, Polat, Fatih, additional, Poodt, Ingrid G.M., additional, Posma, Lisanne A.E., additional, Prette, Jeroen F., additional, Pultrum, Bareld B., additional, Qaderi, Seyed M., additional, van Rees, Jan M., additional, Renger, Rutger-Jan, additional, Rombouts, Anouk J.M., additional, Roosen, Lodewijk J., additional, Roskott-ten Brinke, Ellen A., additional, Rothbarth, Joost, additional, Rouw, Dennis B., additional, Rozema, Tom, additional, Rütten, Heidi, additional, Rutten, Harm J.T., additional, van der Sande, Marit E., additional, Schaafsma, Boudewijn E., additional, Schasfoort, Renske A., additional, Scheurkogel, Merel M., additional, Schouten van der Velden, Arjan P., additional, Schreurs, Wilhelmina H., additional, Schuivens, Puck M.E., additional, Sietses, Colin, additional, Simons, Petra C.G., additional, Slob, Marjan J., additional, Slooter, Gerrit D., additional, van der Sluis, Martsje, additional, Smalbroek, Bo P., additional, Smits, Anke B., additional, Spillenaar-Bilgen, Ernst J., additional, Spruit, Patty H., additional, Stam, Tanja C., additional, Stoker, Jaap, additional, Talsma, Aaldert K., additional, Temmink, Sofieke J.D., additional, The, G.Y. Mireille, additional, Tielbeek, Jeroen A.W., additional, van Tilborg, Aukje A.J.M., additional, van Tilborg, Fiek, additional, van Trier, Dorothée, additional, Tuynman, Jurriaan B., additional, van der Valk, Maxime J.M., additional, Vanhooymissen, Inge J.S., additional, Vasbinder, G. Boudewijn C., additional, Veeken, Cornelis J., additional, Velema, Laura A., additional, van de Ven, Anthony W.H., additional, Verdaasdonk, Emiel G.G., additional, Verduin, Wouter M., additional, Verhagen, Tim, additional, Verheijen, Paul M., additional, Vermaas, Maarten, additional, Verrijssen, An-Sofie E., additional, Verschuur, Anna V.D., additional, Schaik, Harmke Verwoerd-van, additional, Vliegen, Roy F.A., additional, Voets, Sophie, additional, Vogelaar, F. Jeroen, additional, Vogelij, Clementine L.A., additional, Vos-Westerman, Johanna, additional, de Vries, Marianne, additional, Vroemen, Joy C., additional, van Vugt, Bas S.T., additional, Wegdam, Johannes A., additional, van Wely, Bob J., additional, Westerterp, Marinke, additional, van Westerveld, Paul P., additional, van Westreenen, Henderik L., additional, Wijma, Allard G., additional, de Wilt, Johannes H.W., additional, de Wit, Bart W.K., additional, Wit, Fennie, additional, Woensdregt, Karlijn, additional, van Woerden, Victor, additional, van der Wolf, Floor S.W., additional, van der Wolk, Sander, additional, Wybenga, Johannes M., additional, van der Zaag, Edwin S., additional, Zamaray, Bobby, additional, Zandvoort, Herman J.A., additional, van der Zee, Dennis, additional, Zeilstra, Annette P., additional, Zheng, Kang J., additional, Zimmerman, David D.E., additional, and Zorgdrager, Marcel, additional

Published
2024
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66. Semiautomatic Assessment of the Terminal Ileum and Colon in Patients with Crohn Disease Using MRI (the VIGOR++ Project)

Author

Puylaert, Carl A.J., Schüffler, Peter J., Naziroglu, Robiel E., Tielbeek, Jeroen A.W., Li, Zhang, Makanyanga, Jesica C., Tutein Nolthenius, Charlotte J., Nio, C. Yung, Pendsé, Douglas A., Menys, Alex, Ponsioen, Cyriel Y., Atkinson, David, Forbes, Alastair, Buhmann, Joachim M., Fuchs, Thomas J., Hatzakis, Haralambos, van Vliet, Lucas J., Stoker, Jaap, Taylor, Stuart A., and Vos, Frans M.

Published
2018
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68. MRI in addition to CT in patients scheduled for local therapy of colorectal liver metastases (CAMINO): an international, multicentre, prospective, diagnostic accuracy trial

Author

Görgec, Burak, primary, Hansen, Ingrid S, additional, Kemmerich, Gunter, additional, Syversveen, Trygve, additional, Abu Hilal, Mohammed, additional, Belt, Eric J T, additional, Bosscha, Koop, additional, Burgmans, Mark C, additional, Cappendijk, Vincent C, additional, D'Hondt, Mathieu, additional, Edwin, Bjørn, additional, van Erkel, Arian R, additional, Gielkens, Hugo A J, additional, Grünhagen, Dirk J, additional, Gobardhan, Paul D, additional, Hartgrink, Henk H, additional, Horsthuis, Karin, additional, Klompenhouwer, Elisabeth G, additional, Kok, Niels F M, additional, Kint, Peter A M, additional, Kuhlmann, Koert, additional, Leclercq, Wouter K G, additional, Lips, Daan J, additional, Lutin, Bart, additional, Maas, Monique, additional, Marsman, Hendrik A, additional, Meijerink, Martijn, additional, Meyer, Yannick, additional, Morone, Mario, additional, Peringa, Jan, additional, Sijberden, Jasper P, additional, van Delden, Otto M, additional, van den Bergh, Janneke E, additional, Vanhooymissen, Inge J S, additional, Vermaas, Maarten, additional, Willemssen, François E J A, additional, Dijkgraaf, Marcel G W, additional, Bossuyt, Patrick M, additional, Swijnenburg, Rutger-Jan, additional, Fretland, Åsmund A, additional, Verhoef, Cornelis, additional, Besselink, Marc G, additional, Stoker, Jaap, additional, Ayez, Ninos, additional, Bnà, Claudio, additional, van den Boom, Rivka, additional, Lambregts, Doenja J.M., additional, Liefers, Gerrit-Jan, additional, de Meyere, Celine, additional, Draaisma, Werner A., additional, Gerhards, Michael F., additional, Imani, Farshad, additional, Ruers, Theo .J.M., additional, Liem, Mike S.L., additional, Serafino, Gian Piero, additional, van Beek, Hermen C., additional, van der Hoeven, Joost A.B., additional, Veeken, Cornelis J., additional, and Zonderhuis, Babs M., additional

Published
2023
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70. Pneumonia pattern recognition on ultra-low-dose CT does not allow for a reliable differentiation between viral and bacterial pneumonia: A multicentre observer study

Author

van den Berk, Inge A.H., primary, M.N.P. Kanglie, Maadrika, additional, van Engelen, Tjitske S.R., additional, Hovinga de Boer, Marieke C., additional, de Monyé, Wouter, additional, Bipat, Shandra, additional, Bossuyt, Patrick M.M., additional, Prins, Jan M., additional, and Stoker, Jaap, additional

Published
2023
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71. Marked difference in liver fat measured by histology vs. magnetic resonance-proton density fat fraction: A meta-analysis

Author

Qadri, Sami, primary, Vartiainen, Emilia, additional, Lahelma, Mari, additional, Porthan, Kimmo, additional, Tang, An, additional, Idilman, Ilkay S., additional, Runge, Jurgen H., additional, Juuti, Anne, additional, Penttilä, Anne K., additional, Dabek, Juhani, additional, Lehtimäki, Tiina E., additional, Seppänen, Wenla, additional, Arola, Johanna, additional, Arkkila, Perttu, additional, Stoker, Jaap, additional, Karcaaltincaba, Musturay, additional, Pavlides, Michael, additional, Loomba, Rohit, additional, Sirlin, Claude B., additional, Tukiainen, Taru, additional, and Yki-Järvinen, Hannele, additional

Published
2023
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75. MR Elastography of the Pancreas: Bowel Preparation and Repeatability Assessment in Pancreatic Cancer Patients and Healthy Controls.

Author

Wassenaar, Nienke P.M., van Schelt, Anne‐Sophie, Schrauben, Eric M., Kop, Marnix P.M., Nio, C. Yung, Wilmink, Johanna W., Besselink, Marc G.H., van Laarhoven, Hanneke W.M., Stoker, Jaap, Nederveen, Aart J., and Runge, Jurgen H.

Subjects
PANCREATIC cancer, PANCREAS, CANCER patients, STATISTICAL reliability, PANCREATIC duct
Abstract

Background: Pancreatic ductal adenocarcinoma (PDAC) stromal viscoelasticity can be measured using MR elastography (MRE). Bowel preparation regimens could affect MRE quality and knowledge on repeatability is crucial for clinical implementation. Purpose: To assess effects of four bowel preparation regimens on MRE quality and to evaluate repeatability and differentiate patients from healthy controls. Study Type: Prospective. Population: 15 controls (41 ± 16 years; 47% female), 16 PDAC patients (one excluded, 66 ± 12 years; 40% female) with 15 age‐/sex‐matched controls (65 ± 11 years; 40% female). Final sample size was 25 controls and 15 PDAC. Field Strength/Sequence: 3‐T, spin‐echo echo‐planar‐imaging, turbo spin‐echo, and fast field echo gradient‐echo. Assessment: Four different regimens were used: fasting; scopolaminebutyl; drinking 0.5 L water; combination of 0.5 L water and scopolaminebutyl. MRE signal‐to‐noise ratio (SNR) was compared between all regimens. MRE repeatability (test–retest) and differences in shear wave speed (SWS) and phase angle (ϕ) were assessed in PDAC and controls. Regions‐of‐interest were defined for tumor, nontumorous (n = 8) tissue in PDAC, and whole pancreas in controls. Two radiologists delineated tumors twice for evaluation of intraobserver and interobserver variability. Statistical Tests: Repeated measures analysis of variance, coefficients of variation (CoVs), Bland–Altman analysis, (un)paired t‐test, Mann–Whitney U‐test, and Wilcoxon signed‐rank test. P‐value<0.05 was considered statistically significant. Results: Preparation regimens did not significantly influence MRE‐SNR. Therefore, the least burdensome preparation (fasting only) was continued. CoVs for tumor SWS were: intrasession (12.8%) and intersession (21.7%), and intraobserver (7.9%) and interobserver (10.3%) comparisons. For controls, CoVs were intrasession (4.6%) and intersession (6.4%). Average SWS for tumor, nontumor, and healthy tissue were: 1.74 ± 0.58, 1.38 ± 0.27, and 1.18 ± 0.16 m/sec (ϕ: 1.02 ± 0.17, 0.91 ± 0.07, and 0.85 ± 0.08 rad), respectively. Significant differences were found between all groups, except for ϕ between healthy–nontumor (P = 0.094). Data Conclusion: The proposed bowel preparation regimens may not influence MRE quality. MRE may be able to differentiate between healthy tissue–tumor and tumor–nontumor. Level of Evidence: 2 Technical Efficacy Stage: 2 [ABSTRACT FROM AUTHOR]

Published
2024
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76. Yield of Screening for COVID-19 in Asymptomatic Patients Before Elective or Emergency Surgery Using Chest CT and RT-PCR (SCOUT): Multicenter Study

Author

Puylaert, Carl A. J., Scheijmans, Jochem C. G., Borgstein, Alexander B. J., Andeweg, Caroline S., Bartels-Rutten, Annemarieke, Beets, Geerard L., van Berge Henegouwen, Mark I., Braak, Sicco J., Couvreur, Roy, Daams, Freek, van Es, Hendrik W., Franken, Lotte C., Grotenhuis, Brechtje A., Hendriks, Eduard R., de Hingh, Ignace H. J. T., Hoeijmakers, Fieke, ten Holder, Joris T., Huisman, Peter M., Kazemier, Geert, van Kesteren, Floortje, van Kesteren, Jurre, Keywani, Kammy, Kuiper, Sara Z., Lange, Maurits D. J., Lobatto, Mark E., du Mée, Arthur W. F., Poeze, Martijn, van Praag, Elise M., van Rossen, Jorit, van Santvoort, Hjalmar C., Sedee, Wouter J. A., Seelen, Leonard W. F., Sharabiany, Sarah, Sosef, Nico L., Quanjel, Marian J. R., Veltman, Jeroen, Verhagen, Tim, van de Vlasakker, Vincent C. J., Weeder, Pepijn D., van Werven, Jochem R., Wesdorp, Nina J., van Dieren, Susan, Han, Alvin X., Russell, Colin A., de Jong, Menno D., Bossuyt, Patrick M. M., Quarles van Ufford, Jet M. E., Prokop, Mathias W., Gisbertz, Suzanne S., Prins, Jan M., Besselink, Marc G., Boermeester, Marja A., Gietema, Hester A., and Stoker, Jaap

Published
2020
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78. Magnetic resonance imaging for clinical management of rectal cancer: Updated recommendations from the 2016 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting

Author

Beets-Tan, Regina G. H., Lambregts, Doenja M. J., Maas, Monique, Bipat, Shandra, Barbaro, Brunella, Curvo-Semedo, Luís, Fenlon, Helen M., Gollub, Marc J., Gourtsoyianni, Sofia, Halligan, Steve, Hoeffel, Christine, Kim, Seung Ho, Laghi, Andrea, Maier, Andrea, Rafaelsen, Søren R., Stoker, Jaap, Taylor, Stuart A., Torkzad, Michael R., and Blomqvist, Lennart

Published
2018
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81. MR Elastography of the Pancreas: Bowel Preparation and Repeatability Assessment in Pancreatic Cancer Patients and Healthy Controls

Author

Wassenaar, Nienke P.M., primary, van Schelt, Anne‐Sophie, additional, Schrauben, Eric M., additional, Kop, Marnix P.M., additional, Nio, C. Yung, additional, Wilmink, Johanna W., additional, Besselink, Marc G.H., additional, van Laarhoven, Hanneke W.M., additional, Stoker, Jaap, additional, Nederveen, Aart J., additional, and Runge, Jurgen H., additional

Published
2023
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85. Deep learning models for automatic tumor segmentation and total tumor volume assessment in patients with colorectal liver metastases

Author

MS CGO, Cancer, Epi Kanker Team B, Wesdorp, Nina J., Zeeuw, J. Michiel, Postma, Sam C.J., Roor, Joran, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M., Moos, Shira, Kemna, Ruby, Vadakkumpadan, Fijoy, Ambrozic, Courtney, van Dieren, Susan, van Amerongen, Martinus J., Chapelle, Thiery, Engelbrecht, Marc R.W., Gerhards, Michael F., Grunhagen, Dirk, van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., Marquering, Henk A., Stoker, Jaap, Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, Kazemier, Geert, MS CGO, Cancer, Epi Kanker Team B, Wesdorp, Nina J., Zeeuw, J. Michiel, Postma, Sam C.J., Roor, Joran, van Waesberghe, Jan Hein T.M., van den Bergh, Janneke E., Nota, Irene M., Moos, Shira, Kemna, Ruby, Vadakkumpadan, Fijoy, Ambrozic, Courtney, van Dieren, Susan, van Amerongen, Martinus J., Chapelle, Thiery, Engelbrecht, Marc R.W., Gerhards, Michael F., Grunhagen, Dirk, van Gulik, Thomas M., Hermans, John J., de Jong, Koert P., Klaase, Joost M., Liem, Mike S.L., van Lienden, Krijn P., Molenaar, I. Quintus, Patijn, Gijs A., Rijken, Arjen M., Ruers, Theo M., Verhoef, Cornelis, de Wilt, Johannes H.W., Marquering, Henk A., Stoker, Jaap, Swijnenburg, Rutger Jan, Punt, Cornelis J.A., Huiskens, Joost, and Kazemier, Geert

Published
2023

86. Single Breath‐Hold MR Elastography for Fast Biomechanical Probing of Pancreatic Stiffness.

Author

van Schelt, Anne‐Sophie, Gottwald, Lukas M., Wassenaar, Nienke P.M., Runge, Jurgen H., Sinkus, Ralph, Stoker, Jaap, Nederveen, Aart J., and Schrauben, Eric M.

Subjects
ELASTOGRAPHY, PANCREATIC duct, FREQUENCIES of oscillating systems, PANCREATIC tumors, COMPRESSED sensing
Abstract

Background: Pancreatic ductal adenocarcinoma (PDAC) stromal disposition is thought to influence chemotherapy efficacy and increase tissue stiffness, which could be quantified noninvasively via MR elastography (MRE). Current methods cause position‐based errors in pancreas location over time, hampering accuracy. It would be beneficial to have a single breath‐hold acquisition. Purpose: To develop and test a single breath‐hold three‐dimensional MRE technique utilizing prospective undersampling and a compressed sensing reconstruction (CS‐MRE). Study Type: Prospective. Population: A total of 30 healthy volunteers (HV) (31 ± 9 years; 33% male) and five patients with PDAC (69 ± 5 years; 80% male). Field Strength/Sequence: 3‐T, GRE Ristretto MRE. Assessment: First, optimization of multi breath‐hold MRE was done in 10 HV using four combinations of vibration frequency, number of measured wave‐phase offsets, and TE and looking at MRE quality measures in the pancreas head. Second, viscoelastic parameters delineated in the pancreas head or tumor of CS‐MRE were compared against (I) 2D and (II) 3D four breath‐hold acquisitions in HV (N = 20) and PDAC patients. Intrasession repeatability was assessed for CS‐MRE in a subgroup of healthy volunteers (N = 15). Statistical Tests: Tests include repeated measures analysis of variance (ANOVA), Bland–Altman analysis, and coefficients of variation (CoVs). A P‐value <.05 was considered statistically significant. Results: Optimization of the four breath‐hold acquisitions resulted in 40 Hz vibration frequency, five wave‐phases, and echo time (TE) = 6.9 msec as the preferred method (4BH‐MRE). CS‐MRE quantitative results did not differ from 4BH‐MRE. Shear wave speed (SWS) and phase angle differed significantly between HV and PDAC patients using 4BH‐MRE or CS‐MRE. The limits of agreement for SWS were [−0.09, 0.10] m/second and the within‐subject CoV was 4.8% for CS‐MRE. Data Conclusion: CS‐MRE might allow a single breath‐hold MRE acquisition with comparable SWS and phase angle as 4BH‐MRE, and it may still enable to differentiate between HV and PDAC. Level of Evidence: 2 Technical Efficacy Stage: 2 [ABSTRACT FROM AUTHOR]

Published
2024
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87. Defining Magnetic Resonance Imaging Treatment Response and Remission in Crohn's Disease: A Systematic Review.

Author

Caron, Bénédicte, Jairath, Vipul, Laurent, Valérie, Stoker, Jaap, Laghi, Andrea, D'Haens, Geert R, Danese, Silvio, and Peyrin-Biroulet, Laurent

Abstract

Background Magnetic resonance imaging is increasingly used to assess treatment response in Crohn's disease clinical trials. We aimed to describe the definition of MRI response and remission as assessed by magnetic resonance enterography [MRE] to evaluate treatment efficacy in these patients. Methods Electronic databases were searched up to May 1, 2023. All published studies enrolling patients with inflammatory bowel disease and assessment of treatment efficacy with MRE were eligible for inclusion. Results Eighteen studies were included. All studies were performed in patients with Crohn's disease. The study period ranged from 2008 to 2023. The majority of studies used endoscopy as the reference standard [61.1%]. MRE response was defined in 11 studies [61.1%]. Five scores and nine different definitions were proposed for MRE response. MRE remission was defined in 12 studies [66.7%]. Three scores and nine different definitions for MRE remission were described. The MaRIA score was the most frequent index used to evaluate MRE response [63.6%] and remission [41.7%]. MRE response was defined as MaRIA score <11 in 63.6% of studies using this index. In 60% of studies using the MaRIA score, MRE remission was defined as MaRIA score <7. In addition, 11 different time points of assessment were reported, ranging from 6 weeks to years. Conclusion In this systematic review, significant heterogeneity in the definition of MRE response and remission evaluated in patients with Crohn's disease was observed. Harmonization of eligibility and outcome criteria for MRE in Crohn's Disease clinical trials is needed. [ABSTRACT FROM AUTHOR]

Published
2024
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91. Semi-automatic Crohn’s Disease Severity Estimation on MR Imaging

Author

Schüffler, Peter J., Mahapatra, Dwarikanath, Naziroglu, Robiel, Li, Zhang, Puylaert, Carl A. J., Andriantsimiavona, Rado, Vos, Franciscus M., Pendsé, Doug A., Yung Nio, C., Stoker, Jaap, Taylor, Stuart A., Buhmann, Joachim M., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Yoshida, Hiroyuki, editor, Näppi, Janne J., editor, and Saini, Sanjay, editor

Published
2014
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92. Combining Multiple Expert Annotations Using Semi-supervised Learning and Graph Cuts for Crohn’s Disease Segmentation

Author

Mahapatra, Dwarikanath, Schüffler, Peter J., Tielbeek, Jeroen A. W., Puylaert, Carl A. J., Makanyanga, Jesica C., Menys, Alex, Andriantsimiavona, Rado, Stoker, Jaap, Taylor, Stuart A., Vos, Franciscus M., Buhmann, Joachim M., Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Yoshida, Hiroyuki, editor, Näppi, Janne J., editor, and Saini, Sanjay, editor

Published
2014
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94. A Model Development Pipeline for Crohn’s Disease Severity Assessment from Magnetic Resonance Images

Author

Schüffler, Peter J., Mahapatra, Dwarikanath, Tielbeek, Jeroen A. W., Vos, Franciscus M., Makanyanga, Jesica, Pendsé, Doug A., Nio, C. Yung, Stoker, Jaap, Taylor, Stuart A., Buhmann, Joachim M., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Yoshida, Hiroyuki, editor, Warfield, Simon, editor, and Vannier, Michael W., editor

Published
2013
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95. Colon Cancer

Author

Liedenbaum, Marjolein H., Stoker, Jaap, Neri, Emanuele, editor, Faggioni, Lorenzo, editor, and Bartolozzi, Carlo, editor

Published
2013
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