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60. Benefits, harms, and stakeholder perspectives regarding opioid therapy for pain in individuals with metastatic cancer: A Protocol Paper (Preprint)

Author

Jones, Katie, primary, White, Gretchen, additional, Bennett, Antonia, additional, Bulls, Hailey, additional, Escott, Paula, additional, Orris, Sarah, additional, Escott, Elizabeth, additional, Fischer, Stacey, additional, Hamm, Megan, additional, Krishnamurti, Tamar, additional, Wong, Risa, additional, LeBlanc, Thomas W., additional, Liebschutz, Jane, additional, Meghani, Salimah, additional, Smith, Cardinale, additional, Temel, Jennifer, additional, Ritchie, Christine, additional, and Merlin, Jessica, additional

Published
2023
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61. Opioid therapy for pain in individuals with metastatic cancer: benefits, harms, and stakeholder perspectives: A Protocol Paper (Preprint)

Author

Jones, Katie, primary, White, Gretchen, additional, Bennett, Antonia, additional, Bulls, Hailey, additional, Escott, Paula, additional, Orris, Sarah, additional, Escott, Elizabeth, additional, Fischer, Stacey, additional, Hamm, Megan, additional, Krishnamurti, Tamar, additional, Wong, Risa, additional, LeBlanc, Thomas, additional, Liebschutz, Jane, additional, Meghani, Salimah, additional, Smith, Cardinale, additional, Temel, Jennifer, additional, Ritchie, Christine, additional, and Merlin, Jessica, additional

Published
2023
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62. Clinician Perceptions of Barriers and Facilitators for Delivering Early Integrated Palliative Care via Telehealth

Author

Sadang, Katrina Grace, primary, Centracchio, Joely A., additional, Turk, Yael, additional, Park, Elyse, additional, Feliciano, Josephine L., additional, Chua, Isaac S., additional, Blackhall, Leslie, additional, Silveira, Maria J., additional, Fischer, Stacy M., additional, Rabow, Michael, additional, Zachariah, Finly, additional, Grey, Carl, additional, Campbell, Toby C., additional, Strand, Jacob, additional, Temel, Jennifer S., additional, and Greer, Joseph A., additional

Published
2023
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64. QOL-08. LONGITUDINAL EFFECTS OF A PSYCHOLOGICAL INTERVENTION FOR CAREGIVERS OF PATIENTS WITH PRIMARY MALIGNANT BRAIN TUMORS: SECONDARY ANALYSIS OF A RANDOMIZED CONTROLLED TRIAL

Author

Strander, Sumita, primary, Podgurski, Alyx, additional, Datta, Shibani, additional, Pintro, Kedie, additional, Horick, Nora, additional, Greer, Joseph, additional, Traeger, Lara, additional, El-Jawahri, Areej, additional, Sannes, Timothy, additional, Temel, Jennifer, additional, Jacobs, Jamie, additional, and Forst, Deborah, additional

Published
2023
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68. Integrative Oncology Care of Symptoms of Anxiety and Depression in Adults With Cancer: Society for Integrative Oncology–ASCO Guideline

Author

Carlson, Linda E., primary, Ismaila, Nofisat, additional, Addington, Elizabeth L., additional, Asher, Gary N., additional, Atreya, Chloe, additional, Balneaves, Lynda G., additional, Bradt, Joke, additional, Fuller-Shavel, Nina, additional, Goodman, Joseph, additional, Hoffman, Caroline J., additional, Huston, Alissa, additional, Mehta, Ashwin, additional, Paller, Channing J., additional, Richardson, Kimberly, additional, Seely, Dugald, additional, Siwik, Chelsea J., additional, Temel, Jennifer S., additional, and Rowland, Julia H., additional

Published
2023
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70. Delivering high-quality and affordable care throughout the cancer care continuum.

Author

Shih, Ya-Chen, Ganz, Patricia, Aberle, Denise, Abernethy, Amy, Bekelman, Justin, Brawley, Otis, Goodwin, James, Hu, Jim, Schrag, Deborah, Temel, Jennifer, and Schnipper, Lowell

Subjects
Continuity of Patient Care, Delivery of Health Care, Health Care Costs, Humans, Neoplasms, United States
Abstract

The national cost of cancer care is projected to reach $173 billion by 2020, increasing from $125 billion in 2010. This steep upward cost trajectory has placed enormous an financial burden on patients, their families, and society as a whole and raised major concern about the ability of the health care system to provide and sustain high-quality cancer care. To better understand the cost drivers of cancer care and explore approaches that will mitigate the problem, the National Cancer Policy Forum of the Institute of Medicine held a workshop entitled Delivering Affordable Cancer Care in the 21st Century in October 2012. Workshop participants included bioethicists, health economists, primary care physicians, and medical, surgical, and radiation oncologists, from both academic and community settings. All speakers expressed a sense of urgency about the affordability of cancer care resulting from the future demographic trend as well as the high cost of emerging cancer therapies and rapid diffusion of new technologies in the absence to evidence indicating improved outcomes for patients. This article is our summary of presentations at the workshop that highlighted the overuse and underuse of screening, treatments, and technologies throughout the cancer care continuum in oncology practice in the United States.

Published
2013

71. The Diverse Landscape of Palliative Care Clinics

Author

Smith, Alexander K, Thai, Julie N, Bakitas, Marie A, Meier, Diane E, Spragens, Lynn H, Temel, Jennifer S, Weissman, David E, and Rabow, Michael W

Subjects
Health Services and Systems, Nursing, Health Sciences, Clinical Research, Cancer, Pain Research, Chronic Pain, Behavioral and Social Science, Health Services, 7.2 End of life care, Management of diseases and conditions, Good Health and Well Being, Ambulatory Care Facilities, Cross-Sectional Studies, Health Care Surveys, Health Facility Size, Humans, Palliative Care, Personnel Staffing and Scheduling, Referral and Consultation, United States, Workforce, Clinical Sciences, Public Health and Health Services, Gerontology, Health services and systems
Abstract

BackgroundMany health care organizations are interested in instituting a palliative care clinic. However, there are insufficient published data regarding existing practices to inform the development of new programs.ObjectiveOur objective was to obtain in-depth information about palliative care clinics.MethodsWe conducted a cross-sectional survey of 20 outpatient palliative care practices in diverse care settings. The survey included both closed- and open-ended questions regarding practice size, utilization of services, staffing, referrals, services offered, funding, impetus for starting, and challenges.ResultsTwenty of 21 (95%) practices responded. Practices self-identified as: hospital-based (n=7), within an oncology division/cancer center (n=5), part of an integrated health system (n=6), and hospice-based (n=2). The majority of referred patients had a cancer diagnosis. Additional common diagnoses included chronic obstructive pulmonary disease, neurologic disorders, and congestive heart failure. All practices ranked "pain management" and "determining goals of care" as the most common reasons for referrals. Twelve practices staffed fewer than 5 half-days of clinic per week, with 7 operating only one half-day per week. Practices were staffed by a mixture of physicians, advanced practice nurses or nurse practitioners, nurses, or social workers. Eighteen practices expected their practice to grow within the next year. Eleven practices noted a staffing shortage and 8 had a wait time of a week or more for a new patient appointment. Only 12 practices provide 24/7 coverage. Billing and institutional support were the most common funding sources. Most practices described starting because inpatient palliative providers perceived poor quality outpatient care in the outpatient setting. The most common challenges included: funding for staffing (11) and being overwhelmed with referrals (8).ConclusionsOnce established, outpatient palliative care practices anticipate rapid growth. In this context, outpatient practices must plan for increased staffing and develop a sustainable financial model.

Published
2013

73. Quality of life and mood of older patients with acute myeloid leukemia (AML) receiving intensive and non-intensive chemotherapy

Author

El-Jawahri, Areej, Abel, Gregory A., Traeger, Lara, Waldman, Lauren, Markovitz, Netana, VanDusen, Harry, Fathi, Amir, Steensma, David P., LeBlanc, Thomas W., Horick, Nora K., DeAngelo, Daniel J., Wadleigh, Martha, Hobbs, Gabriela, Foster, Julia, Brunner, Andrew M., Amrein, Philip, Stone, Richard M., Temel, Jennifer S., and Greer, Joseph A.

Published
2019
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74. Study protocol for NeuroCARE: a randomised controlled trial of a psychological intervention for caregivers of patients with primary malignant brain tumours

Author

Forst, Deborah Anne, primary, Rhee, John Y, additional, Mesa, Michelle Marie, additional, Podgurski, Alyx F, additional, Strander, Sumita Madhok, additional, Datta, Shibani, additional, Kaslow-Zieve, Emilia, additional, Horick, Nora K, additional, Greer, Joseph A, additional, El-Jawahri, Areej, additional, Sannes, Timothy S, additional, Temel, Jennifer S, additional, and Jacobs, Jamie, additional

Published
2023
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81. Effect of Perioperative Palliative Care on Health-Related Quality of Life Among Patients Undergoing Surgery for Cancer

Author

Aslakson, Rebecca A., primary, Rickerson, Elizabeth, additional, Fahy, Bridget, additional, Waterman, Brittany, additional, Siden, Rachel, additional, Colborn, Kathryn, additional, Smith, Shelby, additional, Verano, Mae, additional, Lira, Isaac, additional, Hollahan, Caroline, additional, Siddiqi, Amn, additional, Johnson, Kemba, additional, Chandrashekaran, Shivani, additional, Harris, Elizabeth, additional, Nudotor, Richard, additional, Baker, Joshua, additional, Heidari, Shireen N., additional, Poultsides, George, additional, Conca-Cheng, Alison M., additional, Cook Chapman, Allyson, additional, Lessios, Anna Sophia, additional, Holdsworth, Laura M., additional, Gustin, Jillian, additional, Ejaz, Aslam, additional, Pawlik, Timothy, additional, Miller, Judi, additional, Morris, Arden M., additional, Tulsky, James A., additional, Lorenz, Karl, additional, Temel, Jennifer S., additional, Smith, Thomas J., additional, and Johnston, Fabian, additional

Published
2023
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86. Supplementary Tables from Spectrum of Mechanisms of Resistance to Crizotinib and Lorlatinib in ROS1 Fusion–Positive Lung Cancer

Author

Lin, Jessica J., primary, Choudhury, Noura J., primary, Yoda, Satoshi, primary, Zhu, Viola W., primary, Johnson, Ted W., primary, Sakhtemani, Ramin, primary, Dagogo-Jack, Ibiayi, primary, Digumarthy, Subba R., primary, Lee, Charlotte, primary, Do, Andrew, primary, Peterson, Jennifer, primary, Prutisto-Chang, Kylie, primary, Malik, Wafa, primary, Hubbeling, Harper G., primary, Langenbucher, Adam, primary, Schoenfeld, Adam J., primary, Falcon, Christina J., primary, Temel, Jennifer S., primary, Sequist, Lecia V., primary, Yeap, Beow Y., primary, Lennerz, Jochen K., primary, Shaw, Alice T., primary, Lawrence, Michael S., primary, Ou, Sai-Hong Ignatius, primary, Hata, Aaron N., primary, Drilon, Alexander, primary, and Gainor, Justin F., primary

Published
2023
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91. Psychological mobile app for patients with acute myeloid leukemia (AML): A pilot randomized clinical trial

Author

El‐Jawahri, Areej, primary, Luskin, Marlise R., additional, Greer, Joseph A., additional, Traeger, Lara, additional, Lavoie, Mitchell, additional, Vaughn, Dagny Marie, additional, Andrews, Stephanie, additional, Yang, Daniel, additional, Boateng, Kofi Y., additional, Newcomb, Richard A., additional, Ufere, Nneka N., additional, Fathi, Amir T., additional, Hobbs, Gabriela, additional, Brunner, Andrew, additional, Abel, Gregory A., additional, Stone, Richard M., additional, DeAngelo, Daniel J., additional, Wadleigh, Martha, additional, and Temel, Jennifer S., additional

Published
2023
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92. Characterizing Distress and Identifying Modifiable Intervention Targets for Family Caregivers of Patients with Malignant Gliomas

Author

Forst, Deborah A., primary, Kaslow-Zieve, Emilia R., additional, Hansen, Andrea, additional, Mesa, Michelle, additional, Landay, Sophia L., additional, Quain, Kit M., additional, Sereno, Isabella, additional, El-Jawahri, Areej, additional, Greer, Joseph A., additional, Temel, Jennifer S., additional, and Jacobs, Jamie M., additional

Published
2023
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93. Effect of a Symptom Monitoring Intervention for Patients Hospitalized With Advanced Cancer: A Randomized Clinical Trial

Author

Nipp, Ryan D., Horick, Nora K., Qian, Carolyn L., Knight, Helen P., Kaslow-Zieve, Emilia R., Azoba, Chinenye C., Elyze, Madeleine, Landay, Sophia L., Kay, Paul S., Ryan, David P., Jackson, Vicki A., Greer, Joseph A., El-Jawahri, Areej, and Temel, Jennifer S.

Subjects
Adult, Hospitalization, Male, Cancer Research, Oncology, Neoplasms, Humans, Female, Self Report, Anxiety, Middle Aged, Original Investigation
Abstract

IMPORTANCE: Symptom monitoring interventions are increasingly becoming the standard of care in oncology, but studies assessing these interventions in the hospital setting are lacking. OBJECTIVE: To evaluate the effect of a symptom monitoring intervention on symptom burden and health care use among hospitalized patients with advanced cancer. DESIGN, SETTING, AND PARTICIPANTS: This nonblinded randomized clinical trial conducted from February 12, 2018, to October 30, 2019, assessed 321 hospitalized adult patients with advanced cancer and admitted to the inpatient oncology services of an academic hospital. Data obtained through November 13, 2020, were included in analyses, and all analyses assessed the intent-to-treat population. INTERVENTIONS: Patients in both the intervention and usual care groups reported their symptoms using the Edmonton Symptom Assessment System (ESAS) and the 4-item Patient Health Questionnaire-4 (PHQ-4) daily via tablet computers. Patients assigned to the intervention had their symptom reports displayed during daily oncology rounds, with alerts for moderate, severe, or worsening symptoms. Patients assigned to usual care did not have their symptom reports displayed to their clinical teams. MAIN OUTCOMES AND MEASURES: The primary outcome was the proportion of days with improved symptoms, and the secondary outcomes were hospital length of stay and readmission rates. Linear regression was used to evaluate differences in hospital length of stay. Competing-risk regression (with death treated as a competing event) was used to compare differences in time to first unplanned readmission within 30 days. RESULTS: From February 12, 2018, to October 30, 2019, 390 patients (76.2% enrollment rate) were randomized. Study analyses to assess change in symptom burden included 321 of 390 patients (82.3%) who had 2 or more days of symptom reports completed (usual care, 161 of 193; intervention, 160 of 197). Participants had a mean (SD) age of 63.6 (12.8) years and were mostly male (180; 56.1%), self-reported as White (291; 90.7%), and married (230; 71.7%). The most common cancer type was gastrointestinal (118 patients; 36.8%), followed by lung (60 patients; 18.7%), genitourinary (39 patients; 12.1%), and breast (29 patients; 9.0%). No significant differences were detected between the intervention and usual care for the proportion of days with improved ESAS-physical (unstandardized coefficient [B] = −0.02; 95% CI, –0.10 to 0.05; P = .56), ESAS-total (B = −0.05; 95% CI, –0.12 to 0.02; P = .17), PHQ-4–depression (B = −0.02; 95% CI, –0.08 to 0.04; P = .55), and PHQ-4–anxiety (B = −0.04; 95% CI, –0.10 to 0.03; P = .29) symptoms. Intervention patients also did not differ significantly from patients receiving usual care for the secondary end points of hospital length of stay (7.59 vs 7.47 days; B = 0.13; 95% CI, –1.04 to 1.29; P = .83) and 30-day readmission rates (26.5% vs 33.8%; hazard ratio, 0.73; 95% CI, 0.48-1.09; P = .12). CONCLUSIONS AND RELEVANCE: This randomized clinical trial found that for hospitalized patients with advanced cancer, the assessed symptom monitoring intervention did not have a significant effect on patients’ symptom burden or health care use. These findings do not support the routine integration of this type of symptom monitoring intervention for hospitalized patients with advanced cancer. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03396510

Published
2023

98. Health-Related Quality of Life and Depression Symptoms in a Cross Section of Patients with Advanced Lung Cancer before and during the COVID-19 Pandemic

Author

Petrillo, Laura A., primary, El-Jawahri, Areej, additional, Heuer, Lauren B., additional, Post, Kathryn, additional, Gallagher, Emily R., additional, Trotter, Chardria, additional, Elyze, Madeleine, additional, Vyas, Charu, additional, Plotke, Rachel, additional, Turk, Yael R., additional, Han, Jacqueline, additional, Temel, Jennifer S., additional, and Greer, Joseph A., additional

Published
2022
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