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51. Utility of HbA1c assessment in people with diabetes awaiting liver transplantation

Author

Bhattacharjee, D., Vracar, S., Round, R. A., Nightingale, P. G., Williams, J. A., Gkoutos, G. V., Stratton, I. M., Parker, R., Luzio, S. D., Webber, J., Manley, S. E., Roberts, G. A., and Ghosh, S.

Subjects
Blood Glucose, Glycated Hemoglobin, Liver Cirrhosis, Male, Disease Management, Erythrocytes, Abnormal, Middle Aged, Liver Transplantation, Research: Care Delivery, Predictive Value of Tests, Erythrocyte Count, Humans, Diabetic Nephropathies, Female, Care Delivery, Research Articles, Aged
Abstract

Aims To investigate the relationship between HbA1c and glucose in people with co‐existing liver disease and diabetes awaiting transplant, and in those with diabetes but no liver disease. Methods HbA1c and random plasma glucose data were collected for 125 people with diabetes without liver disease and for 29 people awaiting liver transplant with diabetes and cirrhosis. Cirrhosis was caused by non‐alcoholic fatty liver disease, hepatitis C, alcoholic liver disease, hereditary haemochromatosis, polycystic liver/kidneys, cryptogenic/non‐cirrhotic portal hypertension and α‐1‐antitrypsin‐related disease. Results The median (interquartile range) age of the diabetes with cirrhosis group was 55 (49–63) years compared to 60 (50–71) years (P=0.13) in the group without cirrhosis. In the diabetes with cirrhosis group there were 21 men (72%) compared with 86 men (69%) in the group with diabetes and no cirrhosis (P=0.82). Of the group with diabetes and cirrhosis, 27 people (93%) were of white European ethnicity, two (7%) were South Asian and none was of Afro‐Caribbean/other ethnicity compared with 94 (75%), 16 (13%), 10 (8%)/5 (4%), respectively, in the group with diabetes and no cirrhosis (P=0.20). Median (interquartile range) HbA1c was 41 (32–56) mmol/mol [5.9 (5.1–7.3)%] vs 61 (52–70) mmol/mol [7.7 (6.9–8.6)%] (P, What's new? HbA1c may not be an accurate reflection of blood glucose for the diagnosis/monitoring of diabetes in people with other illnesses or on certain drugs; people with diabetes and liver disease awaiting transplantation are one such group.HbA1c was found to be depressed relative to random plasma glucose by 20 mmol/mol in people with diabetes and cirrhosis (n = 28) compared to people with diabetes but no liver disease (n = 125); however, HbA1c was elevated in one person with cirrhosis attributable to α‐1‐antitrypsin disorder.Compromised HbA1c may be related to haematological differences associated with liver disease involving erythrocyte half‐life, with shorter/longer times giving less/more opportunity for glycation of haemoglobin.

Published
2019

53. THE CLOSED FUND ALTERNATIVE

Author

Hairs, C. J., Arnold, M., Gustar, A. J., Hare, D. J. P., Needleman, P. D., Tuley, P. J., and Webber, J. M.

Published
1999

56. Research at Oxford: Some Abstracts

Author

Wahhab, Muhammad Abdel, Amanat, A., El Azmeh, A., Badran, Margot Farranto, Binzagr, Olfet, Cigar, Norman, Fanous, W., Seikaly, M., Sirriyyah, Hussein, Tarbush, Mohammad, and Webber, J.

Published
1976

60. From site-focused intervention towards landscape-scale surface water management using Synthetic Stream Networks and Rapid Scenario Screening

Author

Webber, J. L. (author), Wigley, S. (author), Paling, N. (author), Kapelan, Z. (author), Fu, G. (author), Webber, J. L. (author), Wigley, S. (author), Paling, N. (author), Kapelan, Z. (author), and Fu, G. (author)

Abstract

This research addresses the need to transform success in technical understanding and practical implementation of surface water management (SWM) interventions at a site-scale towards integrated landscape-scale management. We achieve this through targeting the informative preliminary stages of strategic design, where broad, early and effective exploration of opportunities can enhance and direct a regional SWM perspective. We present a new method, ‘Synthetic Stream Networks’ (SSN), capable of meeting these requirements by taking advantage of easily accessible data, likely to be available during regional screening. We find that results from the SSN are validated by existing, ‘downstream’ focused data (90% of the river network is within 30 m of an associated SSN flow path), with the added advantage of extending understanding of surface water exceedance flow paths and watersheds into the upper catchment, thus establishing a foundational and physically based sub-catchment management unit exploring surface water connectivity at a catchment and landscape scale. We also demonstrate collaborative advantages of twinning the new SSN method with ‘Rapid Scenario Screening’ (RSS) to develop a novel approach for identifying, exploring and evaluating SWM interventions. Overall, we find that this approach addresses challenges of integrating understanding from sub-catchment, catchment and landscape perspectives within surface water management., Sanitary Engineering

Published
2021
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61. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group

Author

Wyckoff, M. H., Singletary, E. M., Soar, J., Olasveengen, T. M., Greif, R., Liley, H. G., Zideman, D., Bhanji, F., Andersen, L. W., Avis, S. R., Aziz, K., Bendall, J. C., Berry, D. C., Borra, V., Bottiger, B. W., Bradley, R., Bray, J. E., Breckwoldt, J., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Davis, P. G., de Almeida, M. F., de Caen, A. R., de Paiva, E. F., Deakin, C. D., Djarv, T., Douma, M. J., Drennan, I. R., Duff, J. P., Eastwood, K. J., El-Naggar, W., Epstein, J. L., Escalante, R., Fabres, J. G., Fawke, J., Finn, J. C., Foglia, E. E., Folke, F., Freeman, K., Gilfoyle, E., Goolsby, C. A., Grove, A., Guinsburg, R., Hatanaka, T., Hazinski, M. F., Heriot, G. S., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hung, K. K. C., Hsu, C. H., Ikeyama, T., Isayama, T., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lockey, A. S., Malta Hansen, C., Markenson, D., Matsuyama, T., Mckinlay, C. J. D., Mehrabian, A., Merchant, R. M., Meyran, D., Morley, P. T., Morrison, L. J., Nation, K. J., Nemeth, M., Neumar, R. W., Nicholson, T., Niermeyer, S., Nikolaou, N., Nishiyama, C., O'Neil, B. J., Orkin, A. M., Osemeke, O., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, Claudio, Sawyer, T., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Smyth, M. A., Soll, R. F., Sugiura, T., Taylor-Phillips, S., Trevisanuto, D., Vaillancourt, C., Wang, T. -L., Weiner, G. M., Welsford, M., Wigginton, J., Wyllie, J. P., Yeung, J., Nolan, J. P., Berg, K. M., Abelairas-Gomez, C., Barcala-Furelos, R., Beerman, S. B., Bierens, J., Cacciola, Sofia, Cellini, J., Claesson, A., Court, R., D'Arrigo, Sonia, De Brier, N., Dunne, C. L., Elsenga, H. E., Johnson, S., Kleven, G., Maconochie, I., Mecrow, T., Morgan, P., Otto, Q., Palmieri, T. L., Parnia, S., Pawar, R., Pereira, J., Rudd, S., Scapigliati, Andrea, Schmidt, A., Seesink, J., Sempsrott, J. R., Szpilman, D., Warner, D. S., Webber, J. B., West, R. L., Sandroni C. (ORCID:0000-0002-8878-2611), Cacciola S., D'Arrigo S. (ORCID:0000-0001-6740-3195), Scapigliati A. (ORCID:0000-0002-4044-2343), Wyckoff, M. H., Singletary, E. M., Soar, J., Olasveengen, T. M., Greif, R., Liley, H. G., Zideman, D., Bhanji, F., Andersen, L. W., Avis, S. R., Aziz, K., Bendall, J. C., Berry, D. C., Borra, V., Bottiger, B. W., Bradley, R., Bray, J. E., Breckwoldt, J., Carlson, J. N., Cassan, P., Castren, M., Chang, W. -T., Charlton, N. P., Cheng, A., Chung, S. P., Considine, J., Costa-Nobre, D. T., Couper, K., Dainty, K. N., Davis, P. G., de Almeida, M. F., de Caen, A. R., de Paiva, E. F., Deakin, C. D., Djarv, T., Douma, M. J., Drennan, I. R., Duff, J. P., Eastwood, K. J., El-Naggar, W., Epstein, J. L., Escalante, R., Fabres, J. G., Fawke, J., Finn, J. C., Foglia, E. E., Folke, F., Freeman, K., Gilfoyle, E., Goolsby, C. A., Grove, A., Guinsburg, R., Hatanaka, T., Hazinski, M. F., Heriot, G. S., Hirsch, K. G., Holmberg, M. J., Hosono, S., Hsieh, M. -J., Hung, K. K. C., Hsu, C. H., Ikeyama, T., Isayama, T., Kapadia, V. S., Kawakami, M. D., Kim, H. -S., Kloeck, D. A., Kudenchuk, P. J., Lagina, A. T., Lauridsen, K. G., Lavonas, E. J., Lockey, A. S., Malta Hansen, C., Markenson, D., Matsuyama, T., Mckinlay, C. J. D., Mehrabian, A., Merchant, R. M., Meyran, D., Morley, P. T., Morrison, L. J., Nation, K. J., Nemeth, M., Neumar, R. W., Nicholson, T., Niermeyer, S., Nikolaou, N., Nishiyama, C., O'Neil, B. J., Orkin, A. M., Osemeke, O., Parr, M. J., Patocka, C., Pellegrino, J. L., Perkins, G. D., Perlman, J. M., Rabi, Y., Reynolds, J. C., Ristagno, G., Roehr, C. C., Sakamoto, T., Sandroni, Claudio, Sawyer, T., Schmolzer, G. M., Schnaubelt, S., Semeraro, F., Skrifvars, M. B., Smith, C. M., Smyth, M. A., Soll, R. F., Sugiura, T., Taylor-Phillips, S., Trevisanuto, D., Vaillancourt, C., Wang, T. -L., Weiner, G. M., Welsford, M., Wigginton, J., Wyllie, J. P., Yeung, J., Nolan, J. P., Berg, K. M., Abelairas-Gomez, C., Barcala-Furelos, R., Beerman, S. B., Bierens, J., Cacciola, Sofia, Cellini, J., Claesson, A., Court, R., D'Arrigo, Sonia, De Brier, N., Dunne, C. L., Elsenga, H. E., Johnson, S., Kleven, G., Maconochie, I., Mecrow, T., Morgan, P., Otto, Q., Palmieri, T. L., Parnia, S., Pawar, R., Pereira, J., Rudd, S., Scapigliati, Andrea, Schmidt, A., Seesink, J., Sempsrott, J. R., Szpilman, D., Warner, D. S., Webber, J. B., West, R. L., Sandroni C. (ORCID:0000-0002-8878-2611), Cacciola S., D'Arrigo S. (ORCID:0000-0001-6740-3195), and Scapigliati A. (ORCID:0000-0002-4044-2343)

Abstract

The International Liaison Committee on Resuscitation initiated a continuous review of new, peer-reviewed published cardiopulmonary resuscitation science. This is the fifth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations; a more comprehensive review was done in 2020. This latest summary addresses the most recently published resuscitation evidence reviewed by International Liaison Committee on Resuscitation task force science experts. Topics covered by systematic reviews in this summary include resuscitation topics of video-based dispatch systems; head-up cardiopulmonary resuscitation; early coronary angiography after return of spontaneous circulation; cardiopulmonary resuscitation in the prone patient; cord management at birth for preterm and term infants; devices for administering positive-pressure ventilation at birth; family presence during neonatal resuscitation; self-directed, digitally based basic life support education and training in adults and children; coronavirus disease 2019 infection risk to rescuers from patients in cardiac arrest; and first aid topics, including cooling with water for thermal burns, oral rehydration for exertional dehydration, pediatric tourniquet use, and methods of tick removal. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the quality of the evidence, according to the Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations or good practice statements. Insights into the deliberations of the task forces are provided in Justification and Evidence-to-Decision Framework Highlights sections. In addition, the task forces listed priority knowledge gaps for further research.

Published
2021

69. A Comparison between the Characteristics of a Biochar-Npk Granule and a Commercial Npk Granule for Application in the Soil

Author

Tahery, Sara, primary, Munroe, Paul, additional, Marjo, Christopher E., additional, Rawal, Aditya, additional, Horvat, Joseph, additional, Mohammed, Mohanad, additional, Webber, J. Beau W., additional, Arns, Ji-Youn, additional, Arns, Christoph H., additional, Pan, Genxing, additional, Ronjun, Bian, additional, and Joseph, Stephen, additional

Published
2021
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71. The working homer.

Author

Webber, J. A., Library of Congress, and Webber, J. A.

Subjects
Pigeons
Published
1904

93. POnTE Project: Phytophthora spp. on trees in Britain through the Tree Health Diagnostic and Advisory Service at Forest Research

Author

Perez-Sierra, A., Gorton, C., A, Lewis, Chitty R, Van Der Linde, S., Armstrong, A., Hendry, S., Green, S., Brasier, C., and Webber, J.

Subjects
fungi, food and beverages
Abstract

Diseases caused by Phytophthora species have consistently been in the top ten reported problems on trees at the Tree Health Diagnostic and Advisory Service (THDAS) at Forest Research. A total of 227 Phytophthora reports have been submitted to THDAS since 2015 on 26 different tree genera. Phytophthora was isolated from these hosts and where possible was identified to species level by sequencing their ITS region with the primers TS4-ITS6. In 195 cases Phytophthora was identified to species level and in 32 cases confirmation was only based on the positive result of a lateral flow device (LFD). In total 19 different Phytophthora species were identified of which three were first records for Britain, P. foliorum on Rhododendron, P. siskiyouensis on Alnus incana and the hybrid P. gonapodyides x P. chlamydospora on Fagus sylvatica. The five most common identified species were P. plurivora followed by P. austrocedri, P. cinnamomi, P. pseudosyringae and P. cambivora. Phytophthora plurivora was recorded in 48 cases, 24 of which were identified on bleeding lesions on Tilia; P. austrocedri was mainly recorded on roots of Juniper; P. cinnamomi was mainly detected on roots/soil of Castanea sativa and P. pseudosyringae was primarily detected on bleeding lesions of Fagus and Nothofagus. Pathogenicity tests were carried out and Koch’s Postulates were confirmed for the species that were detected for the first time in Britain. Furthermore, the susceptibility of different hosts to P. foliorum and of five different Alnus species to P. siskiyouensis was tested under laboratory conditions to assess their potential threat to British trees. Results on the species detected, the main hosts affected, and the value of the reports received at THDAS will be discussed.

Published
2019
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100. Multi-band magnetotransport in exfoliated thin films of Cu x Bi2Se3

Author

Alexander-Webber, J. A., Huang, J., Beilsten-Edmands, J, Čermák, Patrik, Drašar, Čestmír, Nicholas, R.J., Coldea, A.I., Alexander-Webber, J. A., Huang, J., Beilsten-Edmands, J, Čermák, Patrik, Drašar, Čestmír, Nicholas, R.J., and Coldea, A.I.

Abstract

We report magnetotransport studies in thin (<100 nm) exfoliated films of Cu x Bi2Se3 and we detect an unusual electronic transition at low temperatures. Bulk crystals show weak superconductivity with K and a possible electronic phase transition around 200 K. Following exfoliation, superconductivity is supressed and a strongly temperature dependent multi-band conductivity is observed for T < 30 K. This transition between competing conducting channels may be enhanced due to the presence of electronic ordering, and could be affected by the presence of an effective internal stress due to Cu intercalation. By fitting to the weak antilocalisation conductivity correction at low magnetic fields we confirm that the low temperature regime maintains a quantum phase coherence length nm indicating the presence of topologically protected surface states., Pojednáváme o magnetotransportních studiích na tenkých (<100 nm) exfoliovaných vrstvách CuxBi2Se3 a zjišťujeme neobvyklý elektronický přechod při nízkých teplotách. Objemové krystaly vykazují slabou supravodivost s Tc ~ 3,5 K a možný elektronický fázový přechod okolo 200 K. Po exfoliaci je supravodivost potlačena a silně teplotně závislá více-pásová vodivost je pozorována při T < 30 K. Tento přechod mezi konkurenčními vodivostními kanály může být zvýšen kvůli přítomnosti elektronického uspořádání a může být ovlivněn přítomností účinného vnitřního pnutí kvůli interkalaci Cu. Fitováním korekce na slabou nelokalizovanou vodivost při nízkých magnetických polích potvrzujeme, že nízkoteplotní režim udržuje kvantovou fázovou koherenční délku L>100 nm, což indikuje přítomnost topologicky chráněných povrchových stavů.

Published
2019

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