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337 results on '"Wu, Chuandong"'

76. Efficient and Selective Adsorption of Cationic Dye Malachite Green by Kiwi-Peel-Based Biosorbents.

Author

Zhao, Yanjun, Liu, Xintong, Li, Wenhui, Pei, Suyun, Ren, Yifan, Li, Xinyang, Qu, Chen, Wu, Chuandong, and Liu, Jiemin

Subjects
MALACHITE green, ADSORPTION kinetics, ADSORPTION (Chemistry), ADSORPTION isotherms, LANGMUIR isotherms, COLOR removal in water purification, DYES & dyeing, BASIC dyes
Abstract

In this study, pristine kiwi peel (KP) and nitric acid modified kiwi peel (NA-KP) based adsorbents were prepared and evaluated for selective removal of cationic dye. The morphology and chemical structure of KP and NA-KP were fully characterized and compared, and results showed nitric acid modification introduced more functional groups. Moreover, the adsorption kinetics and isotherms of malachite green (MG) by KP and NA-KP were investigated and discussed. The results showed that the adsorption process of MG onto KP followed a pseudo-second-order kinetic model and the Langmuir isotherm model, while the adsorption process of MG onto NA-KP followed a pseudo-first-order kinetic model and the Freundlich isotherm model. Notably, the Langmuir maximum adsorption capacity of NA-KP was 580.61 mg g−1, which was superior to that of KP (297.15 mg g−1). Furthermore, thermodynamic studies demonstrated the feasible, spontaneous, and endothermic nature of the adsorption process of MG by NA-KP. Importantly, NA-KP showed superior selectivity to KP towards cationic dye MG against anionic dye methyl orange (MO). When the molar ratio of MG/MO was 1:1, the separation factor (αMG/MO) of NA-KP was 698.10, which was 5.93 times of KP. In addition, hydrogen bonding, π-π interactions, and electrostatic interaction played important roles during the MG adsorption process by NA-KP. This work provided a low-cost, eco-friendly, and efficient option for the selective removal of cationic dye from dyeing wastewater. [ABSTRACT FROM AUTHOR]

Published
2023
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77. PEGylated Recombinant Human Growth Hormone Jintrolong® Exhibits Good Long-Term Safety in Cynomolgus Monkeys and Human Pediatric Growth Hormone Deficiency Patients

Author

Wu, Wei, Zhou, Juan, Wu, Chuandong, Zhou, Qian, Li, Xiaoyu, Zhang, Yanlin, Zuo, Conglin, Yin, Jun, Hou, Ling, Wang, Shuyang, Gao, Hongyang, Luo, Tianhong, Jin, Lei, Zhong, Enhong, Wang, Yingwu, and Luo, Xiaoping

Subjects
Endocrinology, Diabetes and Metabolism
Abstract

Jintrolong® is a long-acting PEGylated recombinant human growth hormone (PEG-rhGH) developed for weekly injection in patients with pediatric growth hormone deficiency (PGHD). Although PEG modification of therapeutic proteins is generally considered safe, concerns persist about the potential for adverse vacuolation in tissues with long-term exposure to PEG-included therapies, particularly in children. We assessed the safety of Jintrolong® in cynomolgus monkeys with an examination of vacuolation in the brain choroid plexus (CP) and reported long-term clinical safety data obtained from children with PGHD. The toxicity of Jintrolong® was assessed following the 52-week administration with doses at 0.3, 1, or 3 mg/kg/week. The levels of vacuolation of CP in animals were dose-dependent and at least partially reversible after a 104- or 157-week recovery period. Vacuolation in the CP epithelium did not lead to obvious subcellular structural or cell functional abnormalities. Compared with the clinical dose of 0.2 mg/kg/week Jintrolong® in PGHD patients, exposure in monkeys under NOAEL 3 mg/kg/week exhibited safety margins greater than 120.5, the predicted minimum dose to induce vacuolation in monkeys is equivalent to 1.29 mg/kg/week in humans, which is 6.45-fold higher than the clinical dose. The safety data acquired in clinical trials for Jintrolong® were also analyzed, which included phase III (360 patients), phase IV (3,000 patients) of 26-week treatment, and a follow-up study with treatment lasting for 3 years. There was no statistically significant difference in the incidence of adverse reactions between the Jintrolong® group and the daily rhGH control group (no PEG), and no new adverse effects (AE) were observed in the Jintrolong® group at the clinical therapeutic dose of 0.2 mg/kg/week.

Published
2022

81. Rapid granulation of aerobic granular sludge and maintaining its stability by combining the effects of multi-ionic matrix and bio-carrier in a continuous-flow membrane bioreactor

Author

Qiu, Bangqiao, primary, Liao, Guohao, additional, Wu, Chuandong, additional, Dai, Chencheng, additional, Bin, Liying, additional, Gao, Xinlei, additional, Zhao, Yan, additional, Li, Ping, additional, Huang, Shaosong, additional, Fu, Fenglian, additional, and Tang, Bing, additional

Published
2022
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87. Environmental Odour

Author

Schauberger, Günther, primary, Piringer, Martin, additional, Wu, Chuandong, additional, and Koziel, Jacek A., additional

Published
2021
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95. Three-dimensional geometry, pore parameter, and fractal characteristic analyses of medium-density fiberboard by X-ray tomography, coupling with scanning electron microscopy and mercury intrusion porosimetry

Author

Shao, Huiqi, primary, Guo, Zhongbao, additional, Li, Wenhui, additional, Fang, Lei, additional, Qin, Menghao, additional, Cai, Hanmei, additional, Zhang, Yan, additional, Guan, Bo, additional, Wu, Chuandong, additional, and Liu, Jiemin, additional

Published
2020
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100. Enhancement of the anaerobic biodegradation efficiency of azo dye by anthraquinone-loaded biochar biofilm: factors affecting biofilm formation and the enhancement mechanism

Author

Wang, Guangyuan, Cui, Chenhao, Wang, Yuqian, Pang, Jiwei, Yang, Shanshan, Wu, Chuandong, Fang, Rui, Zhang, Luyan, Ren, Nanqi, and Ding, Jie

Abstract

AQS-BC biofilm system exhibited superiority and stability in long-term anaerobic biodecolorization of RR2.AQS-BC biofilm effectively promoted the production of VFAs and alleviated the inhibitory of RR2 on methanogenesis.AQS-BC biofilm had a higher EPS content, denser structure, and higher microbial diversity compared to BC biofilm.Four inoculation conditions affecting biofilm formation were elucidated.

Published
2024
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