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ABSTRACT Background Methods Results Conclusion Adverse childhood experiences (ACEs) are known contributors to lifelong mental health challenges. Despite studies linking ACEs to increased risk of adverse postpartum mental health outcomes, a systematic review on the occurrence of postpartum post‐traumatic stress disorder (PTSD) in women with ACEs is lacking.A systematic search was conducted in seven databases to retrieve studies from inception to January 31, 2024. A random‐effects model was used to quantify weighted estimates of postpartum PTSD incidence. Statistical analysis was conducted using R software.Seven studies were included in the system review. One study was identified as an outlier and excluded from the meta‐analysis. Among the six remaining studies, 1186 women exposed to ACEs were identified, with 249 of them experiencing postpartum PTSD. The estimated incidence of postpartum PTSD among women exposed to ACEs was 22.6% (95% confidence interval [CI] 16.1%–29.8%). Subgroup analysis revealed significant variations in incidence depending on study settings (p < 0.01) and PTSD assessment methods (p < 0.01). Due to multicollinearity among the primary variables, a meta‐regression to identify factors influencing study heterogeneity was not conducted.The incidence of postpartum PTSD was 22.6% in women with ACEs, higher than that observed in the general obstetric population. This finding suggests the need to provide comprehensive postpartum care for these women. [ABSTRACT FROM AUTHOR]

ABSTRACT Introduction Methods Results Conclusions Although the benefits of doula care during childbirth are well‐known, its impact on childbirth‐related post‐traumatic stress disorder (CB‐PTSD) symptoms are less thoroughly characterized. This study aimed to explore the association between doula care and CB‐PTSD symptoms and the potential mediating role of childbirth experience on this association.A prospective cohort study was conducted in a hospital in China, enrolling women with singleton live vaginal births. The exposure and primary outcome factors of interest were doula care and CB‐PTSD symptoms, with childbirth experience as a mediating factor. Questionnaires were administered to collect baseline data and childbirth experience at 3 days postpartum, and CB‐PTSD symptoms from participants at 42 days postpartum. Linear regression analysis was used to analyze the relationship between doula care, childbirth experience, and CB‐PTSD symptoms, while the mediating role of childbirth experience was analyzed using the SPSS (PROCESS) modeling tool.A total of 445 eligible women were included in the final analysis, including 120 who received doula care and 325 who did not. Linear regression analyses found that doula care was independently associated with CB‐PTSD symptoms (β = −0.11, p < 0.05) and childbirth experience (β = 0.50, p < 0.001). Childbirth experience was significantly associated with CB‐PTSD symptoms (β = −0.17, p < 0.001). Childbirth experience mediated the association between doula care and CB‐PTSD symptoms (indirect effect = −1.08, 95% CI −1.91 to −0.10), even after adjusting for potential confounders.Childbirth experience serves as a mediator of the association between doula care and CB‐PTSD symptoms. By providing supportive care for women during childbirth, their childbirth experience could be improved, thereby reducing the risk of CB‐PTSD symptoms. [ABSTRACT FROM AUTHOR]

Objective: To assess the association between women's perceived birth trauma and risk of postpartum depression (PPD)., Methods: We conducted a prospective cohort study in China between December 2018 and November 2019. Women aged 18-45 years who had a singleton live birth at a university teaching hospital were enrolled after written consent was obtained. PPD was defined as a score of 13 or more on the Chinese version of the Edinburgh Postnatal Depression Scale. We used multiple log-binomial regression analysis to estimate the independent association between perceived birth trauma and PPD., Results: A total of 650 eligible women were included in the final analysis. Of them, 245 (37.69%) had self-reported perceived birth trauma and 188 (28.92%) developed PPD. The PPD rate was 42.04% in women with perceived birth trauma, compared with 20.99% in women without perceived birth trauma (crude relative risk [RR] 2.46, 95% confidence interval [CI] 1.48-3.72). The increased risk of PPD for women with perceived birth trauma remained after adjustment for sociodemographic and obstetric factors (adjusted RR 2.13, 95% CI 1.69-3.28)., Conclusion: Perceived birth trauma may be an important risk factor for PPD in Chinese women. Supportive care for women who perceived childbirth as a trauma may help to reduce the risk of PPD., (© 2021 International Federation of Gynecology and Obstetrics.)

Objective: To investigate the efficacy of oral sweet solutions in relieving pain caused by vaccination in infants aged 1 to 12 months., Methods: Related databases were searched to find related randomized control trails (RCTs). The quality of these RCTs was evaluated. The Meta analysis was performed using RevMan 5.3., Results: A total of 20 RCTs involving 2 376 infants were included, and quality assessment showed that 6 RCTs had grade A quality and 14 had grade B quality. The Meta analysis showed that compared with sterile water, 25%-75% oral sweet solution significantly reduced crying time (WMD=-21.16, 95%CI -39.66 to -2.77, P<0.05) and the proportion of crying time (the duration of crying /3-minute periods after the injection) (WMD=-13.83, 95%CI -20.88 to -6.78, P<0.01), while the crying time showed no significant difference between the group treated with oral administration of 12% sucrose solution and non-intervention group. Co, Onclusions: Oral sweet solution (25%-75%; 2 mL) given 2 minutes before vaccination can effectively relieve the pain caused by vaccination in infants aged 1-12 months.

Objective: To investigate the PSA level of 16 222 asymptematic men in Shenzhen who came from different areas of China, in order to find out the PSA levels of Chinese men., Methods: Serum samples of 16 222 men who came to Peking University Shenzhen Hospital for health examination were collected, all of whom had no symptoms. Their serum PSA levels were measured with MEIA with ILMA instrument., Results: The mean PSA level of the 16 222 men in our research was 0.986 μg/L, and the standard deviation was 1.190. The 95% percentile was 2.375 μg/L. Of all the cases ,the 95% percentile of 15 498 was lower than 2.5 μg/L, about 95.472%;that of 699 was between 2.5-10.0 μg/L, about 4.306%;And if took 4.0 μg/L as reference value,that of 15 948 cases was below 4.0 μg/L, about 98.244%;that of 249 was between 4.0-10.0 μg/L, about 1.534%;That of only 36 cases was greater than 10.0 μg/L, about 0.222%;The 95% percentiles of the different age groups were: 10-19 years 0-1.067 μg/L;20-29 years 0-1.818 μg/L;30-39 years 0-1.914 μg/L;40-49 years 0-2.001 μg/L;50-59 years 0-2.900 μg/L;60-69 years 0-5.862 μg/L;70-79 years 0-8.536 μg/L;elder than 80 years 0-12.869 μg/L;There were statistic differences between thedifferent age groups., Conclusion: Our data demonstrate that the mean value of PSA levels of Chinese men is 0.986 μg/L at present stage, and the 95% percentile is 2.375 g/L. Our PSA levels of each age group are different from Oesterling's reference values which are commonly accepted in the world. The PSA level of Chinese men who are under 60 years is lower than that of Euramericans, while the PSA level of Chinese men who are above 60 years is higher than that of Euramericans. This shows that for the men who are under 60 the reference value should be 2.5 μg/L, while for the men who are above 60, we could still use 4 μg/L as reference value.