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362 results on '"Xu, Chunyang"'

65. Bioinformatics analysis of gene expression network regulation in osteogenic differentiation of human bone marrow mesenchymal stem cells RunningTitle: Bioinformatics analysis of osteogenic differentiation

Author

zhang, shuhong, primary, Yao, Jingke, additional, Bai, Xiaoyuan, additional, Li, Lihua, additional, Li, Shuang, additional, Xu, Xinhui, additional, Sun, Yongkun, additional, Xu, Chunyang, additional, Zhang, Hu, additional, and Wang, Xianwei, additional

Published
2022
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72. Customizing Heterointerfaces in Multilevel Hollow Architecture Constructed by Magnetic Spindle Arrays Using the Polymerizing‐Etching Strategy for Boosting Microwave Absorption

Author

Xu, Chunyang, primary, Liu, Panbo, additional, Wu, Zhengchen, additional, Zhang, Huibin, additional, Zhang, Ruixuan, additional, Zhang, Chang, additional, Wang, Lei, additional, Wang, Longyuan, additional, Yang, Bingtong, additional, Yang, Ziqi, additional, You, Wenbin, additional, and Che, Renchao, additional

Published
2022
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82. The Effect of MSCs Derived from the Human Umbilical Cord Transduced by Fibroblast Growth Factor-20 on Parkinson’s Disease

Author

Li Jinfeng, Wang Yunliang, Liu Xinshan, Wang Shanshan, Xu Chunyang, Xue Peng, Yang Xiaopeng, Xu Zhixiu, Yin Honglei, Cao Xia, Duan Haifeng, and Cao Bingzhen

Subjects
Internal medicine, RC31-1245
Abstract

Cell therapy is a potential therapeutic approach for Parkinson’s disease (PD). Mesenchymal stem cells derived from the human umbilical cord (hUC-MSCs) give priority to PD patients because of multiple advantages. The appropriate gene transduction of hUC-MSC before transplantation is a promising procedure for cell therapy. Fibroblast growth factor-20 (FGF-20) has been shown to protect dopaminergic neurons against a range of toxic insults in vitro. In this study, the hUC-MSCs were gene transduced with FGF-20, and then we transplanted them into the PD mice model. The results showed that MSC-FGF-20 treatment obviously improved the behavior of PD, accompanied by the increase of tyrosine carboxylase- (TH-) positive cell and dopamine (DA). Furtherly, immunohistochemistry disclosed that MSC-FGF-20 obviously promoted the degradation of nuclear factor-κB (NF-κB), a transcription factor that controls genes encoding proinflammatory cytokines, highly expressed in the nigrostriatal dopaminergic regions in PD patients. Therefore, MSC-FGF-20 has a potential for improving PD, closely related to the degradation of NF-κB.

Published
2016
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94. Vortex tuning magnetization configurations in porous Fe3O4 nanotube with wide microwave absorption frequency.

Author

Zhang, Ruixuan, Wang, Lei, Xu, Chunyang, Liang, Chongyun, Liu, Xianhu, Zhang, Xuefeng, and Che, Renchao

Abstract

The design and optimization of one-dimension (1D) magnetic material are of great importance for the energy conversion, storage and spin electron devices, which remain a huge challenge. Herein, 1D porous Fe3O4 nanotubes (NTs) have been fabricated via a combined process of electrospinning and calcination. In the electrospinning precursors, by regulating the content ratio between two types of polyvinyl pyrrolidone with different molecular weight, porous Fe3O4 NTs with vortex-domain configuration have been fabricated. Based on the unique 1D nanotube structure encapsulated with multi-domains, the composite Fe3O4 NTs exhibit high complex permeability (μ′, μ″) values, and hold both strong magnetic storage and dissipation capacity. Our Fe3O4 NTs exhibit excellent microwave absorption (MA) performance with the maximum reflection loss value of −57.1 dB and the efficient absorption bandwidth of 12.0 GHz. The generated magnetic vortices make the crucial contribution to the spin-wave resonance which improves the MA dissipation under high-frequency. Related magnetic flux line distribution and magnetic domain moment were confirmed by the electron holography and micro-magnetic simulation, respectively, providing the deep insight to the microwave absorption mechanism. [ABSTRACT FROM AUTHOR]

Published
2022
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