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84. Examining pre‐service teachers' teaching anxiety during student teaching: A Chinese perspective.

Author

Ao, Narentuya, Zhang, Manman, and Tian, Guoxiu

Subjects
*SECONDARY school teachers, *JOB descriptions, *HIGH school teachers, *PRIMARY school teachers, *EDUCATIONAL background
Abstract

To better understand pre‐service teachers' teaching anxiety in specific cultural contexts and promote their overall anticipatory socialisation process, this study investigated the level, dimensions and causality of Chinese pre‐service teachers' teaching anxiety during student teaching. We conducted a survey of 426 Chinese pre‐service teachers who were at the end of their bachelor or master programmes to become primary or secondary school teachers. The results of this study revealed that the participants experienced moderate anxiety (M = 25.51), with more concerns about their professional teaching competencies (M = 10.75) and teaching management ability (M = 7.66) than personal image, personal affairs and evaluation (M = 2.92, 2.35, 1.82). Moreover, gender, educational background, self‐concept, student ability, job demands and job resources were correlated with teaching anxiety. Among these, self‐concept and job demands best explained teaching anxiety with estimated regression weights of −0.541 for self‐concept and 0.079 for job demands (p < .001). This study contributes to the literature on teaching anxiety by exploring culturally specific elements in China and offers valuable implications for interventions to reduce anxiety among pre‐service teachers. [ABSTRACT FROM AUTHOR]

Published
2024
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85. l‐2‐Hydroxyglutarate contributes to tumor radioresistance through regulating the hypoxia‐inducible factor‐1α signaling pathway.

Author

Zhang, Manman, Liu, Yingshuang, Lu, Xinran, Du, Liqing, He, Ningning, Song, Huijuan, Wang, Jinhan, Gu, Yeqing, Yang, Mengmeng, Xu, Chang, Wang, Yan, Ji, Kaihua, and Liu, Qiang

Subjects
*CELLULAR signal transduction, *GENE expression, *HYPOXIA-inducible factor 1, *TUMOR growth, *RENAL cancer, *CELL migration
Abstract

l‐2‐Hydroxyglutarate (l‐2‐HG) has been regarded as a tumor metabolite, and it plays a crucial role in adaptation of tumor cells to hypoxic conditions. However, the role of l‐2‐HG in tumor radioresistance and the underlying mechanism have not yet been revealed. Here, we found that l‐2‐HG exhibited to have radioresistance effect on U87 human glioblastoma cells, which could reduce DNA damage and apoptosis caused by irradiation, promote cell proliferation and migration, and impair G2/M phase arrest. Mechanistically, l‐2‐HG upregulated the protein level of hypoxia‐inducible factor‐1α (HIF‐1α) and the expression levels of HIF‐1α downstream target genes. The knockdown of l‐2‐hydroxyglutarate dehydrogenase (L2HGDH) gene promoted the tumor growth and proliferation of U87 cells in nude mice by increasing HIF‐1α expression level in vivo. In addition, the low expression level of L2HGDH gene was correlated with the short survival of patients with glioma or kidney cancer. In conclusion, our study revealed the role and mechanism of l‐2‐HG in tumor radioresistance and may provide a new perspective for overcoming tumor radioresistance and broaden our comprehension of the role of metabolites in tumor microenvironment. [ABSTRACT FROM AUTHOR]

Published
2024
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86. Research on Convective Cooling and Thermal Protection Characteristics of Integrated Dual-Sided Deflector System.

Author

Zhang, Manman, Jiang, Yi, and Deng, Yueguang

Subjects
SPACE vehicle launching, LAUNCH vehicles (Astronautics), MASS transfer, FLOW simulations, TWO-phase flow, WATER jets
Abstract

Based on the goals of "high reliability, high frequency, rapid launch, and low cost" for space launch sites, an integrated dual-sided deflector system for convective cooling and thermal protection is presented. The interaction process between the gas jet and liquid water jet and its effect on the flow field environment are thoroughly studied using numerical calculation methods. Furthermore, considering the phase-change heat transfer issue in a compressible gas–liquid two-phase flow, and the varying distribution of different bubble shapes and sizes at the gas–liquid interface, a modified Lee model is derived. The research results show that compared to the classical Lee model, the modified Lee model can achieve a higher numerical accuracy in predicting the heat and mass transfer processes in gas–liquid two-phase flows. Through comparative analysis with the traditional dual-sided deflector and the conventional cooling system, the integrated dual-sided deflector system exhibits significant performance advantages in gas flow regulation and flow field environment improvement at the near-ground region of the space launch site. It not only achieves effective flow deflection, but also mitigates the degree of erosion caused by the gas jet on the deflector. This conclusion can provide theoretical references for the thermal protection design of commercial launch vehicle systems at space launch sites. [ABSTRACT FROM AUTHOR]

Published
2024
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92. High intensity interval training vs. moderate intensity continuous training on aerobic capacity and functional capacity in patients with heart failure: a systematic review and meta-analysis

Author

Yang, Changran, primary, Zhang, Lizhuang, additional, Cheng, Yu, additional, Zhang, Manman, additional, Zhao, Yuxin, additional, Zhang, Tianzi, additional, Dong, Jiawang, additional, Xing, Jun, additional, Zhen, Yuzhi, additional, and Wang, Cuihua, additional

Published
2024
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97. Optimized Layout of the Soil Moisture Sensor in Tea Plantations Based on Improved Dijkstra Algorithm

Author

Zhang, Manman, Zhang, Wu, Hong, Xun, Song, Yifan, Rao, Yuan, Gao, Yujia, Sun, Yunyun, Barbosa, Simone Diniz Junqueira, Editorial Board Member, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Kotenko, Igor, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Shen, Hong, editor, and Sang, Yingpeng, editor

Published
2020
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98. Hierarchical Fusion for Gender Recognition Based on Hand Images

Author

Zhang, Manman, Fang, Yuchun, Li, Yifan, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Peng, Yuxin, editor, Liu, Qingshan, editor, Lu, Huchuan, editor, Sun, Zhenan, editor, Liu, Chenglin, editor, Chen, Xilin, editor, Zha, Hongbin, editor, and Yang, Jian, editor

Published
2020
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