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Insufficient selenization and uneven distribution of elements caused by the poor diffusion and reaction activity of selenium clusters is one of the main issues limiting the efficiency of Cu2ZnSn(S,Se)4 (CZTSSe) solar cells. Here, this work designs a simple and feasible strategy to improve the activity of selenium (Se) by implementing high‐temperature treatment on graphite boxes loaded with Se pellets. The rapid adsorption/desorption characteristics of graphite on active gaseous small‐molecule selenium have successfully introduced hyperactive Se4, Se3, and Se2 into the selenization process. The results indicate that the adsorbed non‐toxic gaseous active Se3 and Se4 can quickly and uniformly diffuse into the precursor film at low temperatures, thereby inducing nucleation and grain growth at both surface and back interface simultaneously, which inhibits the upward migration and aggregation of cations, especially Cu, and promotes the homogenization of elements. The overall relatively Cu‐poor chemical environment suppresses the formation of CuZn defects and [2CuZn+SnZn] defect clusters, and also promotes the generation of favorable VCu. The band tail states and non‐radiative recombination are then optimized. Finally, the CZTSSe solar cells achieve a power conversion efficiency (PCE) of 14.5%, with VOC/VOCSQ of 67% being one of the highest in the literature. [ABSTRACT FROM AUTHOR]

In a recent paper (IEEE Trans. Wireless Commun., vol.8, no.9, 2009), Yi and Kim presented an optimum power allocation scheme for bidirectional cooperative networks employing opportunistic source selection (OSS) protocol. However, the optimum power allocation expressions in [1] are proved to be incorrect. We present correct optimum power allocation expressions, which are validated by the simulation results. [ABSTRACT FROM PUBLISHER]

With the high incidence rate, distinctive implant characteristic and unique infection pattern, peri-implantitis (PI) requires a specially designed implant animal model for the researches on the pathogenesis and treatments. Previous small-animal PI models exhibit variability in implant site selection, design, and surgical procedures resulting in unnecessary tissue damage and less effectivity. Herein, a quantitative-analysis-based standardized rat model for transmucosal PI-related research was proposed. After dissecting the anatomic structures of the rat maxilla, we determined that placing the implant anterior to the molars in the rat maxilla streamlined the experimental period and enhanced animal welfare. We standardized the model by controlling the rat strain, gender, and size. The customized implant and a series of matched surgical instruments were appropriately designed. A clear, step-by-step surgical process was established. These designs ensured the success rate, stability, and replicability of the model. Each validation method confirmed the successful construction of the model. This study proposed a quantitative-analysis-based standardized transmucosal PI rat model with improved animal welfare and reliable procedures. This model could provide efficient in vivo insights to study the pathogenesis and treatments of PI and preliminary screening data for further large-animal and clinical trials., Competing Interests: Competing interests: The authors declare that they have no competing interests., (Copyright © 2024 Xingchen Liu et al.)

Objective: To observe the effect and mechanism of electroacupuncture (EA) on non-canonical pathway of hepatocellular pyroptosis in nonalcoholic fatty liver disease (NAFLD)., Methods: Sixty male SD rats were randomly divided into a normal diet group ( n =15) and a high fat modeling group ( n =45). The rats in the high fat modeling group were fed with customized high fat diet for 8 weeks to establish NAFLD model. Thirty successfully modeled rats were selected and randomly divided into a model group ( n =10), an EA group ( n =10) and a non-acupoint with shallow needling group ( n =10), and 10 rats were randomly selected from the normal diet group as the control group additionally. In the EA group, EA was applied at bilateral "Fenglong" (ST 40) and "Ganshu" (BL 18), with disperse-dense wave, in frequency of 4 Hz/20 Hz and in intensity of 3 mA. In the non-acupoint with shallow needling group, shallow needling was delivered at points 5 mm from bilateral "Fenglong" (ST 40) and "Ganshu" (BL 18), the EA stimulation parameters were same as the EA group. The intervention was given once a day, 20 min a time, 5 days a week for 4 weeks in the two groups. After intervention, the liver morphology was observed by oil red "O" staining, the serum levels of lipopolysaccharide (LPS), interleukin (IL)-1β, IL-18 and tumor necrosis factor-α (TNF-α) were detected by ELISA, the protein expression of gasdermin D (GSDMD), GSDMD-N, cysteine aspartic acid specific protease-11 (Caspase-11), IL-1β, IL-18 and TNF-α in liver tissue were detected by Western blot, the mRNA expression of GSDMD, Caspase-11, IL-1β, IL-18 and TNF-α in liver tissue was detected by real-time PCR in rats of each group., Results: In the model group, vacuoles in different size were found in the hepatocellular cytoplasm, and the fat droplets were in schistose accumulation. Compared with the model group, the hepatocellular fat droplets and the degree of hepatic steatosis were reduced in the EA group and the non-acupoint with shallow needling group. Compared with the control group, the serum levels of LPS, IL-1β, IL-18 and TNF-α were increased ( P <0.01), the protein and mRNA expression of GSDMD, Caspase-11, IL-1β, IL-18, TNF-α as well as the protein expression of GSDMD-N in the liver tissue were increased ( P <0.01) in the model group. Compared with the model group, the serum levels of LPS, IL-1β, IL-18 and TNF-α were decreased ( P <0.01), the protein and mRNA expression of GSDMD, IL-1β, IL-18 and TNF-α in the liver tissue were decreased ( P <0.01), the protein expression of GSDMD-N and the mRNA expression of Caspase-11 in the liver tissue were decreased ( P <0.01) in the EA group and the non-acupoint with shallow needling group. Compared with the model group, the protein expression of Caspase-11 in the liver tissue was decreased ( P <0.01) in the EA group. Compared with the non-acupoint with shallow needling group, the serum levels of LPS, IL-1β, IL-18 and TNF-α were decreased ( P <0.01), the protein and mRNA expression of GSDMD, Caspase-11, IL-1β and IL-18 in the liver tissue were decreased ( P <0.01), the protein expression of GSDMD-N and the mRNA expression of TNF-α in the liver tissue were decreased ( P <0.01) in the EA group., Conclusion: EA can inhibit hepatocellular pyroptosis in NAFLD rats, and its mechanism may be related to reducing the serum level of LPS, and down-regulating the expression of the non-canonical pathway related factors i.e. GSDMD, GSDMD-N, Caspase-11, IL-1β, IL-18 and TNF-α.

Tetracyclines are currently the most commonly used class of antibiotics, and their residue issue significantly impacts public health safety. In this study, a surface modification of perovskite with cetyltrimethylammonium bromide led to the generation of stable electrochemiluminescence (ECL) emitters in aqueous systems and improved the biocompatibility of perovskite. A perovskite quantum dot-based ECL sensing strategy was developed. Utilizing the corresponding aptamer of the antibiotics, strain displacement reactions were triggered, disrupting the ECL quenching system composed of perovskite and Ag nanoclusters (Ag NCs) on the electrode surface, generating a signal to achieve quantitative detection of several common tetracycline antibiotics. The perovskite quantum dot provided a strong and stable initial signal, while the efficient catalytic activity of the silver cluster enhanced the recognition sensitivity. Tetracycline, chlortetracycline, and oxytetracycline were used as examples to demonstrate the differentiation and quantitative detection through this method. In addition, the aptasensor exhibited analytical performance with the linear range (0.1-10 μM OTC) and good recovery rates of 94.7% to 101.6% in real samples. This approach has the potential to become a sensitive and practical approach for assessing antibiotic residues., (© 2024 John Wiley & Sons Ltd.)