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653. [Effect of polyanions on macrophage-lymphocyte interaction].

Author

Lysenko AI, Kulakova GS, Romanova MV, and Cherniavskiĭ VI

Subjects
Animals, Ascitic Fluid cytology, B-Lymphocytes immunology, Cells, Cultured, Dextran Sulfate, Mice, Mice, Inbred CBA, Microscopy, Electron, Scanning, T-Lymphocytes immunology, Dextrans pharmacology, Lymphocyte Cooperation drug effects, Lymphocytes immunology, Macrophages immunology, Poly A-U pharmacology, RNA, Fungal pharmacology
Abstract

The effect of polyanions on the interaction of antigen-stimulated macrophages and lymphocytes was studied in vivo. Treatment of cell mixture of macrophages and lymphocytes with poly = A : U or dextran sulfate induced a considerable increase in the number of lymphocytes contacting with macrophages during the first hours of cultivation. Under similar conditions yeast RNA had a certain anticooperative effect. According to the data obtained by scanning electron microscopy, the contacts between the interacting cells were realized by means of cytoplasmic bridges or close membrane connections.

Published
1981

654. [Use of chelates for removal of excess iron from the body].

Author

Meshchanov AIu, Romanova MZh, Kol'tsova GN, and Shcherbinina SP

Subjects
Administration, Oral, Animals, Drug Carriers, Hemochromatosis metabolism, Hemosiderosis metabolism, Humans, Iron metabolism, Iron Chelating Agents administration & dosage, Liposomes, Mice, Rabbits, Rats, Hemochromatosis drug therapy, Hemosiderosis drug therapy, Iron antagonists & inhibitors, Iron Chelating Agents therapeutic use
Published
1989

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