1,165 results on '"Bourdin, Arnaud"'
Search Results
102. Dose-dependent cardiovascular disorders in a rat model with exacerbated emphysema: Implication of inflammation
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Bellanger, Axel, primary, Cazorla, Olivier, additional, Bourdin, Arnaud, additional, Grillet, Pierre-Edouard, additional, Wynands, Quentin, additional, Desplanche, Elodie, additional, Bideaux, Patrice, additional, and Alburquerque, Laurie, additional
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- 2023
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103. Human airway ex vivo models: new tools to study the airway epithelial cell response to SARS-CoV-2 infection
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Assou, Said, primary, Ahmed, Engi, additional, Morichon, Lisa, additional, Nasri, Amel, additional, Foisset, Florent, additional, Bourdais, Carine, additional, Gros, Nathalie, additional, Wong, Sonia, additional, Petit, Aurelie Fort, additional, Vachier, Isabelle, additional, Muriaux, Delphine, additional, Bourdin, Arnaud, additional, and De Vos, John, additional
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- 2023
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104. Muscle sympathetic nerve activity and adaptive servo-ventilation: questions remain
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Jaffuel, Dany, primary, Mallet, Jean Pierre, additional, Roubille, François, additional, and Bourdin, Arnaud, additional
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- 2023
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105. Patterns of adaptive servo-ventilation settings in a real-life multicenter study: pay attention to volume!: Adaptive servo-ventilation settings in real-life conditions
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Jaffuel, Dany, Rabec, Claudio, Philippe, Carole, Mallet, Jean-Pierre, Georges, Marjolaine, Redolfi, Stefania, Palot, Alain, Suehs, Carey M., Nogue, Erika, Molinari, Nicolas, and Bourdin, Arnaud
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- 2020
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106. International severe asthma registry (ISAR): protocol for a global registry
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FitzGerald, J. Mark, Tran, Trung N., Alacqua, Marianna, Altraja, Alan, Backer, Vibeke, Bjermer, Leif, Bjornsdottir, Unnur, Bourdin, Arnaud, Brusselle, Guy, Bulathsinhala, Lakmini, Busby, John, Canonica, Giorgio W., Carter, Victoria, Chaudhry, Isha, Cho, You Sook, Christoff, George, Cosio, Borja G., Costello, Richard W., Eleangovan, Neva, Gibson, Peter G., Heaney, Liam G., Heffler, Enrico, Hew, Mark, Hosseini, Naeimeh, Iwanaga, Takashi, Jackson, David J., Jones, Rupert, Koh, Mariko S., Le, Thao, Lehtimäki, Lauri, Ludviksdottir, Dora, Maitland-van der Zee, Anke H., Menzies-Gow, Andrew, Murray, Ruth B., Papadopoulos, Nikolaos G., Perez-de-Llano, Luis, Peters, Matthew, Pfeffer, Paul E., Popov, Todor A., Porsbjerg, Celeste M., Price, Chris A., Rhee, Chin K., Sadatsafavi, Mohsen, Tohda, Yuji, Wang, Eileen, Wechsler, Michael E., Zangrilli, James, and Price, David B.
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- 2020
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107. Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?
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Pahus, Laurie, Suehs, Carey Meredith, Halimi, Laurence, Bourdin, Arnaud, Chanez, Pascal, Jaffuel, Dany, Marciano, Julie, Gamez, Anne-Sophie, Vachier, Isabelle, and Molinari, Nicolas
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- 2020
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108. What is the remaining status of adaptive servo-ventilation? The results of a real-life multicenter study (OTRLASV-study): Adaptive servo-ventilation in real-life conditions
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Jaffuel, Dany, Philippe, Carole, Rabec, Claudio, Mallet, Jean-Pierre, Georges, Marjolaine, Redolfi, Stefania, Palot, Alain, Suehs, Carey M., Nogue, Erika, Molinari, Nicolas, and Bourdin, Arnaud
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- 2019
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109. Dupilumab sustains efficacy in patients with moderate‐to‐severe type 2 asthma regardless of inhaled corticosteroids dose.
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Pavord, Ian D., Bourdin, Arnaud, Papi, Alberto, Domingo, Christian, Corren, Jonathan, Altincatal, Arman, Radwan, Amr, Pandit‐Abid, Nami, Jacob‐Nara, Juby A., Deniz, Yamo, Rowe, Paul J., Laws, Elizabeth, Lederer, David J., and Hardin, Megan
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DUPILUMAB , *ASTHMA , *MONOCLONAL antibodies , *CORTICOSTEROIDS , *NITRIC oxide - Abstract
Background: Dupilumab, a human monoclonal antibody, blocks the shared receptor component for interleukins‐4/13, key and central drivers of type 2 inflammation. The TRAVERSE (NCT02134028) open‐label extension study demonstrated the long‐term safety and efficacy of dupilumab in patients ≥12 years who completed a previous dupilumab asthma study. The safety profile was consistent with that observed in the parent studies. Here, we assess whether dupilumab sustains long‐term efficacy in patients regardless of inhaled corticosteroid (ICS) dose at parent study baseline (PSBL). Methods: Patients from phase 2b (NCT01854047) or phase 3 (QUEST; NCT02414854) studies receiving high‐ or medium‐dose ICS at PSBL and enrolled in TRAVERSE were included. We analyzed unadjusted annualized severe exacerbation rates, change from PSBL in pre‐bronchodilator (BD) forced expiratory volume in 1 second (FEV1), 5‐item asthma control questionnaire, and type 2 biomarkers in patients with type 2 asthma at baseline (blood eosinophils ≥150 cells/μL or fractional exhaled nitric oxide [FeNO] ≥25 ppb), and subgroups defined by baseline blood eosinophils or FeNO. Results: Of patients with type 2 asthma (n = 1666), 891 (53.5%) were receiving high‐dose ICS at PSBL. In this subgroup, unadjusted exacerbation rates for dupilumab versus placebo were 0.517 versus 1.883 (phase 2b) and 0.571 versus 1.300 (QUEST) over the parent study (52 weeks) and remained low throughout TRAVERSE (0.313–0.494). Improvements in pre‐BD FEV1 were sustained throughout TRAVERSE. Similar clinical efficacy was observed among patients receiving medium‐dose ICS at PSBL and biomarker subgroups. Conclusions: Dupilumab showed sustained efficacy for up to 3 years in patients with uncontrolled, moderate‐to‐severe type 2 asthma on high‐ or medium‐dose ICS. [ABSTRACT FROM AUTHOR]
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- 2023
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110. Tezepelumab for the treatment of severe asthma: a plain language summary of the PATHWAY and NAVIGATOR studies.
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Corren, Jonathan, Menzies-Gow, Andrew, Bimmel, Johan, McGuinness, Anthony, Almqvist, Gun, Bowen, Karin, Griffiths, Janet M, Ponnarambil, Sandhia, Bourdin, Arnaud, Israel, Elliot, Colice, Gene, Brightling, Christopher E, and Wechsler, Michael E
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- 2023
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111. In-depth characterization of pulmonary arterial hypertension in mixed connective tissue disease: a French national multicentre study.
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Chaigne, Benjamin, Chevalier, Kevin, Boucly, Athenaïs, Agard, Christian, Baudet, Antoine, Bourdin, Arnaud, Chabanne, Céline, Cottin, Vincent, Fesler, Pierre, Goupil, François, Jego, Patrick, Launay, David, Lévesque, Hervé, Maurac, Arnaud, Mohamed, Shirine, Tromeur, Cécile, Rottat, Laurence, Sitbon, Olivier, Humbert, Marc, and Mouthon, Luc
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MORTALITY risk factors ,PULMONARY arterial hypertension ,RESEARCH ,PERICARDITIS ,MULTIVARIATE analysis ,INTERSTITIAL lung diseases ,CONNECTIVE tissue diseases ,RISK assessment ,KAPLAN-Meier estimator ,DESCRIPTIVE statistics ,ARTHRITIS ,THROMBOCYTOPENIA ,SMOKING ,SYSTEMIC lupus erythematosus ,DISEASE risk factors ,DISEASE complications - Abstract
Objective Pulmonary arterial hypertension (PAH) is a leading cause of death in MCTD. We aimed to describe PAH in well-characterized MCTD patients. Methods MCTD patients enrolled in the French Pulmonary Hypertension Registry with a PAH diagnosis confirmed by right heart catheterization were included in the study and compared with matched controls: MCTD patients without PAH, SLE patients with PAH and SSc patients with PAH. Survival rates were estimated by the Kaplan–Meier method and risk factors for PAH in MCTD patients and risk factors for mortality in MCTD-PAH were sought using multivariate analyses. Results Thirty-six patients with MCTD-PAH were included in the study. Comparison with MCTD patients without PAH and multivariate analysis revealed that pericarditis, polyarthritis, thrombocytopenia, interstitial lung disease (ILD) and anti-Sm antibodies were independent predictive factors of PAH/PH in MCTD. Estimated survival rates at 1, 5 and 10 years following PAH diagnosis were 83%, 67% and 56%, respectively. MCTD-PAH presentation and survival did not differ from SLE-PAH and SSc-PAH. Multivariate analysis revealed that tobacco exposure was an independent factor predictive of mortality in MCTD-PAH. Conclusion PAH is a rare and severe complication of MCTD associated with a 56% 10-year survival. We identified ILD, pericarditis, thrombocytopenia and anti-Sm antibodies as risk factors for PAH in MCTD and tobacco exposure as a predictor of mortality in MCTD-PAH. [ABSTRACT FROM AUTHOR]
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- 2023
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112. Comparative effectiveness of anti‐IL5 and anti‐IgE biologic classes in patients with severe asthma eligible for both
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Pfeffer, Paul E., primary, Ali, Nasloon, additional, Murray, Ruth, additional, Ulrik, Charlotte, additional, Tran, Trung N., additional, Maspero, Jorge, additional, Peters, Matthew, additional, Christoff, George C., additional, Sadatsafavi, Mohsen, additional, Torres‐Duque, Carlos A., additional, Altraja, Alan, additional, Lehtimäki, Lauri, additional, Papadopoulos, Nikolaos G., additional, Salvi, Sundeep, additional, Costello, Richard W., additional, Cushen, Breda, additional, Heffler, Enrico, additional, Iwanaga, Takashi, additional, Al‐Ahmad, Mona, additional, Larenas‐Linnemann, Désirée, additional, Kuna, Piotr, additional, Fonseca, João A., additional, Al‐Lehebi, Riyad, additional, Rhee, Chin Kook, additional, Perez‐de‐Llano, Luis, additional, Perng Steve, Diahn‐Warng, additional, Mahboub, Bassam, additional, Wang, Eileen, additional, Goh, Celine, additional, Lyu, Juntao, additional, Newell, Anthony, additional, Alacqua, Marianna, additional, Belevskiy, Andrey S., additional, Bhutani, Mohit, additional, Bjermer, Leif, additional, Bjornsdottir, Unnur, additional, Bourdin, Arnaud, additional, Bulow, Anna von, additional, Busby, John, additional, Canonica, Giorgio Walter, additional, Cosio, Borja G., additional, Dorscheid, Delbert R., additional, Muñoz‐Esquerre, Mariana, additional, FitzGerald, J. Mark, additional, Gil, Esther Garcia, additional, Gibson, Peter G., additional, Heaney, Liam G., additional, Hew, Mark, additional, Hilberg, Ole, additional, Hoyte, Flavia, additional, Jackson, David J., additional, Koh, Mariko Siyue, additional, Ko, Hsin‐Kuo Bruce, additional, Lee, Jae Ha, additional, Lehmann, Sverre, additional, Chaves Loureiro, Cláudia, additional, Lúðvíksdóttir, Dóra, additional, Menzies‐Gow, Andrew N., additional, Mitchell, Patrick, additional, Papaioannou, Andriana I., additional, Popov, Todor A., additional, Porsbjerg, Celeste M., additional, Salameh, Laila, additional, Sirena, Concetta, additional, Taillé, Camille, additional, Taube, Christian, additional, Tohda, Yuji, additional, Wechsler, Michael E., additional, and Price, David B., additional
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- 2023
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113. Evaluation of Real-World Mepolizumab Use in Severe Asthma across Europe - the SHARP experience with privacy-preserving federated analysis
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Kroes, Johannes A., primary, Alfonso-Cristancho, Rafael, additional, Bansal, Aruna T., additional, Berret, Emmanuelle, additional, Bieksiene, Kristina, additional, Bourdin, Arnaud, additional, Brussino, Luisa, additional, Canhoto, Diogo, additional, Cardini, Cristina, additional, Celik, Gulfem, additional, Csoma, Zsuzsanna, additional, Dahlén, Barbro, additional, Damadoglu, Ebru, additional, Eger, Katrien, additional, Gauquelin, Lisa, additional, Gemicioglu, Bilun, additional, Goksel, Ozlem, additional, Graff, Sophie, additional, Heffler, Enrico, additional, Hofstee, Hendrik B., additional, Howarth, Peter, additional, Jakes, Rupert W., additional, Jaun, Fabienne, additional, Kalinauskaite-Zukauske, Virginija, additional, Kopač, Peter, additional, Kwon, Namhee, additional, Loureiro, Claudia C., additional, Lozoya García, Victor, additional, Masoli, Matthew, additional, Paula Rezelj, Mariana, additional, De Llano, Luis Pérez, additional, Popović-Grle, Sanja, additional, Ramos-Barbon, David, additional, Sà Sousa, Ana, additional, Samitas, Konstantinos, additional, Schleich, Florence, additional, Sirena, Concetta, additional, Skrgat, Sabina, additional, Zervas, Eleftherios, additional, Zichnalis, George, additional, Bel, Elisabeth H., additional, Sont, Jacob K., additional, Hashimoto, Simone, additional, and Ten Brinke, Anneke, additional
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- 2023
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114. Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory
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Vernisse, Charlotte, primary, Tuaillon, Edouard, additional, Suehs, Carey, additional, Gras, Delphine, additional, Bedin, Anne Sophie, additional, Charriot, Jeremy, additional, Knabe, Lucie, additional, Vachier, Isabelle, additional, Chanez, Pascal, additional, Petit, Aurélie, additional, and Bourdin, Arnaud, additional
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- 2023
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115. Sputum-Rheology-Based Strategy for Guiding Azithromycin Prescription in COPD Patients with Frequent Exacerbations: A Randomized, Controlled Study (“COPD CARhE”)
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Charriot, Jeremy, primary, Maeva, Zysman, additional, Guilleminault, Laurent, additional, Volpato, Mathilde, additional, Fort-Petit, Aurelie, additional, Vachier, Isabelle, additional, Patarin, Jeremy, additional, Suehs, Carey, additional, Engi, Ahmed, additional, Molinari, Nicolas, additional, and Bourdin, Arnaud, additional
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- 2023
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116. Severe Asthma Standard-of-Care Background Medication Reduction With Benralizumab: ANDHI in Practice Substudy
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Louis, Renaud, primary, Harrison, Tim W., additional, Chanez, Pascal, additional, Menzella, Francesco, additional, Philteos, George, additional, Cosio, Borja G., additional, Lugogo, Njira L., additional, de Luiz, Gustavo, additional, Burden, Annie, additional, Adlington, Timothy, additional, Keeling, Nanna, additional, Kwiatek, Justin, additional, Garcia Gil, Esther, additional, Pohl, Wolfgang, additional, Doberer, Daniel, additional, Martinot, Jean Benoit, additional, Deschampheleire, Maud, additional, Himpe, Ulrike, additional, Chapman, Kenneth, additional, Cheema, Amarjit, additional, Dorscheid, Delbert, additional, Ramsey, Clare, additional, Rolf, Jeffrey, additional, Walker, Brandie, additional, Olivenstein, Ronald, additional, Poirier, Claude, additional, Larivee, Pierre, additional, Bjerrum, Anne Sofie, additional, Titlestad, Ingrid, additional, Hilberg, Ole, additional, Kilpeläinen, Maritta, additional, Bonniaud, Philippe, additional, Taillé, Camille, additional, Tiotiu, Iuliana-Angelica, additional, Girodet, Pierre-Olivier, additional, Blanc, François-Xavier, additional, Pradelli, Johana, additional, Didier, Alain, additional, Nocent Ejnaini, Cecilia, additional, Deslee, Gaetan, additional, Pison, Christophe, additional, Douadi, Youcef, additional, Mahay, Guillaume, additional, Devouassoux, Gilles, additional, Melloni, Boris, additional, Roux, Pauline-Marie, additional, Bourdin, Arnaud, additional, Fry, Stephanie, additional, Schaum, Thomas, additional, Schulz, Christian, additional, Skowasch, Dirk, additional, Taube, Christian, additional, Welte, Tobias, additional, Gleiber, Wolfgang, additional, Brehler, Randolf, additional, Schreiber, Jens, additional, Schuette, Wolfgang, additional, Kronsbein, Juliane, additional, Bonnet, Reiner, additional, Beck, Ekkehard, additional, Lacedonia, Donato, additional, Senna, Gianenrico, additional, Caruso, Cristiano, additional, Crimi, Nunzio, additional, Blasi, Francesco, additional, Santus, Pierachille, additional, Canonica, Giorgio Walter, additional, Guarnieri, Gabriella, additional, Pelaia, Girolamo, additional, Milanese, Manlio, additional, Micheletto, Claudio, additional, Corsico, Angelo Guido, additional, Scichilone, Nicola, additional, Spadaro, Giuseppe, additional, Langeveld, Bas, additional, Holters, Jurgen, additional, Willem van den Berg, Jan, additional, Smit, Arthur, additional, Conemans, Lennart, additional, van Veen, Helena, additional, Staaks, Gerald, additional, Lehmann, Sverre, additional, Echave-Sustaeta, Jose Maria, additional, Ribas, Christian Domingo, additional, de Luiz Martinez, Gustavo, additional, Gonzalez Perez, Ruperto, additional, Garcia Rivero, Juan Luis, additional, Gall, Xavier Muñoz, additional, Soto Campos, Jose Gregorio, additional, Mozo, Paloma Campo, additional, Pan, Carmen Vidal, additional, Fernandez, Ana Gomez-Bastero, additional, Tellez, Sergio Campos, additional, Rivera, Carlos Martinez, additional, Bobolea, Irina Diana, additional, Guerrero, Raquel Morillo, additional, Garcia, Ismael Ali, additional, Rodriguez Hermosa, Juan Luis, additional, Stenfors, Nikolai, additional, Tunsäter, Alf, additional, Curiac, Dan, additional, von Garnier, Christophe, additional, Leuppi, Joerg, additional, Schmid-Grendelmeier, Peter, additional, Nasser, Shuaib, additional, Chaudhuri, Rekha, additional, Nordstrom, Monica, additional, Saralaya, Dinesh, additional, Pfeffer, Paul, additional, Mansur, Adel, additional, Short, Philip, additional, Wenzel, Sally, additional, Cherry, William Brett, additional, Zafra, Heidi, additional, Gonzalez, Erika, additional, Soong, Weily, additional, Davis, Benjamin, additional, Kao, Neil, additional, Hussain, Iftikhar, additional, Maselli Caceres, Diego Jose, additional, Harris, James, additional, Calhoun, William, additional, Rodicio, Ileana, additional, Kaufman, David, additional, Moss, Mark, additional, Sztejman, Eric, additional, DeLeon, Samuel, additional, Sumino, Kaharu, additional, Kashyap, Ravindra, additional, Leflein, Jeffrey, additional, Hajal, Rizan, additional, Fakih, Faisal, additional, Hill, David, additional, Lin, Robert, additional, Jarratt, Mikell, additional, Subramaniam, Vijay, additional, Sussman, Robert, additional, Mumneh, Nayla, additional, Reibman, Joan, additional, Darveaux, Jared, additional, Tan, Ricardo, additional, Tanus, Tonny, additional, Sikand, Vinay, additional, Marshall, Gailen, additional, Mehta, Hemalini, additional, Cole, Jeremy, additional, Goodman, Brad, additional, Goss, Deborah, additional, Bardelas, Jose, additional, Milstone, Aaron, additional, Mehta, Vinay, additional, Clore, Lee, additional, Millard, Mark, additional, Palumbo, Michael, additional, Puppala, Dileep, additional, Leong, Mila, additional, Prenner, Bruce, additional, Robinette, Emory, additional, Heidarian Raissy, Hengameh, additional, Fost, David, additional, Pleskow, Warren, additional, Marcus, Michael, additional, Ilowite, Jonathan, additional, Moore, Wendy, additional, Steven, Gary, additional, De la Cruz, Luis, additional, Chupp, Geoffrey, additional, Berger, William, additional, Randolph, Christopher, additional, Holguin, Fernando, additional, Kureishy, Shahrukh, additional, and Campbell, Edward, additional
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- 2023
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117. Local targeting of TSLP: feat or defeat
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Charriot, Jérémy, primary, Ahmed, Engi, additional, and Bourdin, Arnaud, additional
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- 2023
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118. Standard patient training versus Vik-Asthme chatbot-guided training: ‘AsthmaTrain’ – a protocol for a randomised controlled trial for patients with asthma
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Suehs, Carey Meredith, primary, Vachier, Isabelle, additional, Galeazzi, David, additional, Vaast, François, additional, Cardon, Fanny, additional, Molinari, Nicolas, additional, and Bourdin, Arnaud, additional
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- 2023
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119. Definitions of non-response and response to biological therapy for severe asthma: a systematic review
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Khaleva, Ekaterina, primary, Rattu, Anna, additional, Brightling, Chris, additional, Bush, Andrew, additional, Bourdin, Arnaud, additional, Bossios, Apostolos, additional, Chung, Kian Fan, additional, Chaudhuri, Rekha, additional, Coleman, Courtney, additional, Djukanovic, Ratko, additional, Dahlén, Sven-Erik, additional, Exley, Andrew, additional, Fleming, Louise, additional, Fowler, Stephen J., additional, Gupta, Atul, additional, Hamelmann, Eckard, additional, Koppelman, Gerard H., additional, Melén, Erik, additional, Mahler, Vera, additional, Seddon, Paul, additional, Singer, Florian, additional, Porsbjerg, Celeste, additional, Ramiconi, Valeria, additional, Rusconi, Franca, additional, Yasinska, Valentyna, additional, and Roberts, Graham, additional
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- 2023
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120. Germline Mutations of Telomere-Related Genes are a Major Risk Factor for Liver Disease: A Multicentric Transversal Study
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Sidali, Sabrina, primary, Borie, Raphaël, additional, Sicre de Fontbrune, Flore, additional, El Husseini, Kinan, additional, Rautou, Pierre-Emmanuel, additional, Lainey, Elodie, additional, Goria, Odile, additional, Crestani, Bruno, additional, Cadranel, Jacques, additional, Cottin, Vincent, additional, Bunel, Vincent, additional, Dumortier, Jérôme, additional, Jacquemin, Emmanuel, additional, Reboux, Noémi, additional, Hirschi, Sandrine, additional, Bourdin, Arnaud, additional, Meszaros, Magdalena, additional, Dharancy, Sébastien, additional, Hilaire, Sophie, additional, Mallet, Vincent, additional, Reynaud-Gaubert, Martine, additional, Terriou, Louis, additional, Gottrand, Frédéric, additional, Abou Chahla, Wadih, additional, Kahn, Jean-Emmanuel, additional, Carrier, Paul, additional, Saliba, Faouzi, additional, Rubbia-Brandt, Laura, additional, Aubert, John-David, additional, Elkrief, Laure, additional, de Ledinghen, Victor, additional, Abergel, Armand, additional, Tournilhac, Olivier, additional, Houssel, Pauline, additional, Jouneau, Stéphane, additional, Wemeau, Ludivine, additional, Bergeron, Anne, additional, Leblanc, Thierry, additional, Ollivier-Hourmand, Isabelle, additional, Nguyen-Khac, Eric, additional, Morisse-Pradier, Hélène, additional, Ba, Ibrahima, additional, Boileau, Catherine, additional, Roulot-Thoraval, Françoise, additional, Vilgrain, Valérie, additional, Bureau, Christophe, additional, Nunes, Hilario, additional, Naccache, Jean-Marc, additional, Durand, François, additional, Francoz, Claire, additional, Roulot, Dominique, additional, Valla, Dominique-Charles, additional, Paradis, Valérie, additional, Kannengiesser, Caroline, additional, and Plessier, Aurélie, additional
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- 2023
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121. Improvement in severe asthma patients receiving biologics and factors associated with persistent insufficient control: a real-life national study
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Guilleminault, Laurent, primary, Camus, Claire, additional, Raherison-Semjen, Chantal, additional, Capdepon, Audrey, additional, Bourdin, Arnaud, additional, Bonniaud, Philippe, additional, Fry, Stéphanie, additional, Devouassoux, Gilles, additional, Blanc, François-Xavier, additional, Pison, Christophe, additional, Dupin, Clairelyne, additional, Khayath, Naji, additional, Courdeau, Joelle, additional, Valcke-Brossollet, Judith, additional, Nocent-Ejnaini, Cécilia, additional, Rolland, Fabien, additional, Lamandi, Carmen, additional, Proust, Alain, additional, Ozier, Anaig, additional, Portel, Laurent, additional, Gaspard, Wanda, additional, Roux-Claude, Pauline, additional, Beurnier, Antoine, additional, Martinez, Stéphanie, additional, Dot, Jean-Marc, additional, Hennegrave, Florence, additional, Vignal, Guillaume, additional, Auvray, Etienne, additional, Paleiron, Nicolas, additional, Just, Nicolas, additional, Miltgen, Jean, additional, Russier, Maud, additional, Olivier, Cécile, additional, Taillé, Camille, additional, and Didier, Alain, additional
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- 2023
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122. Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study
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Menzies-Gow, Andrew, primary, Wechsler, Michael E, additional, Brightling, Christopher E, additional, Korn, Stephanie, additional, Corren, Jonathan, additional, Israel, Elliot, additional, Chupp, Geoffrey, additional, Bednarczyk, Artur, additional, Ponnarambil, Sandhia, additional, Caveney, Scott, additional, Almqvist, Gun, additional, Gołąbek, Monika, additional, Simonsson, Linda, additional, Lawson, Kaitlyn, additional, Bowen, Karin, additional, Colice, Gene, additional, Hetzel, Jorge Lima, additional, Fiterman, Jussara, additional, Souza Machado, Adelmir, additional, Antila, Martti Anton, additional, Lima, Marina Andrade, additional, Minamoto, Suzana Erico Tanni, additional, Blanco, Daniela Cavalet, additional, Bezerra, Patricia Gomes de Matos, additional, Houle, Pierre-Alain, additional, Lemiere, Catherine, additional, Melenka, Lyle S, additional, Leigh, Richard, additional, Mitchell, Patrick, additional, Anees, Syed, additional, Pek, Bonavuth, additional, Chouinard, Guy, additional, Cheema, Amarjit S, additional, Yang, William Ho-Ching, additional, Philteos, George, additional, Chanez, Pascal, additional, Bourdin, Arnaud, additional, Devouassoux, Gilles, additional, Taille, Camille, additional, De Blay, Frédéric, additional, Leroyer, Christophe, additional, Beurnier, Antoine, additional, Garcia, Gilles, additional, Girodet, Pierre-Olivier, additional, Blanc, François-Xavier, additional, Magnan, Antoine, additional, Wanin, Stéphanie, additional, Just, Jocelyne, additional, Linde, Richard, additional, Zielen, Stefan, additional, Förster, Karin, additional, Geßner, Christian, additional, Jandl, Margret, additional, Buhl, Roland Otto, additional, Kornmann, Marc Oliver, additional, Linnhoff, Anneliese, additional, Ludwig-Sengpiel, Andrea, additional, Ehlers, Martin, additional, Schmoller, Tibor, additional, Steffen, Heiner, additional, Hoffmann, Martin, additional, Kirschner, Joachim, additional, Schmidt, Olaf, additional, Welte, Tobias, additional, Temme, Hilke, additional, Wand, Ori, additional, Bar-Shai, Amir, additional, Izbicki, Gabriel, additional, Berkman, Neville, additional, Fink, Gershon, additional, Shitrit, David, additional, Adir, Yochai, additional, Kuna, Piotr, additional, Rewerska, Barbara, additional, Pisarczyk-Bogacka, Ewa, additional, Kurbacheva, Oksana, additional, Mikhailov, Sergey L, additional, Vasilev, Maksim, additional, Emelyanov, Alexander, additional, Wali, Siraj, additional, Albanna, Amr, additional, van Zyl-Smit, Richard, additional, Abdullah, Ismail, additional, Bernhardi, David, additional, Hoosen, Farzana, additional, Irusen, Elvis, additional, Kalla, Ismail, additional, Lakha, Deepak, additional, Mitha, Essack, additional, Naidoo, Visvakuren, additional, Nell, Haylene, additional, Padayachee, Trevenesan, additional, Reddy, Jeevren, additional, Petrick, Friedrich, additional, van der Walt, Eugene, additional, Vawda, Zubar Fazal Ahmed, additional, Park, Hae-Sim, additional, Lee, Sang Haak, additional, Kim, Mi-Kyeong, additional, Park, Jung-Won, additional, Cho, You Sook, additional, Lee, Byung Jae, additional, Chang, Yoon-Seok, additional, Park, Choon-Sik, additional, Lee, Kwan Ho, additional, Lee, Sook Young, additional, Yoon, HyoungKyu, additional, Sohn, Kyoung Hee, additional, Park, Myung Jae, additional, Min, Kyung Hoon, additional, Cho, Young Joo, additional, Park, Han Ki, additional, Lee, YongChul, additional, Lee, Jaechun, additional, Sheu, Chau-Chyun, additional, Tu, Chih-Yen, additional, Lee, Kang-Yun, additional, Bavbek, Sevim, additional, Gemicioglu, Bilun, additional, Ediger, Dane, additional, Kalkan, Ilkay Koca, additional, Makieieva, Nataliia, additional, Ostrovskyy, Mykola, additional, Dytyatkovs'ka, Yevgeniya, additional, Mostovoy, Yuriy Mykhaylovych, additional, Lebed, Kyrylo, additional, Yakovenko, Oleh, additional, Adams, Atoya, additional, Mooring, Timothy, additional, Torres Jr, Louis, additional, Sexton, Marvin, additional, Thompson, Ernest, additional, Bernstein, Jonathan A, additional, Lisi, Paul, additional, Chappel, Christopher M, additional, Cole, Jeremy, additional, Greenwald, Gary I, additional, Jones, Conigliaro, additional, Klein, Ryan Mitchell, additional, Pham, David N, additional, Spangenthal, Selwyn, additional, Weinstein, Steven F, additional, Windom, Hugh H, additional, Kao, Neil L, additional, Leong, Mila A, additional, Mehta, Vinay, additional, Moore, Wendy C, additional, Bhat, Saligrama, additional, Aish, Bassil, additional, Meltzer, Steven M, additional, Moss, Mark H, additional, Kerwin, Edward M, additional, Delgado, John Palsted, additional, Lucksinger, Gregg Hudson, additional, Thompson, Charles A, additional, Alpizar, Sady A, additional, Vadgama, Sanjay Virgi, additional, Zafar, Zahid, additional, Jacobs, Joshua S, additional, Lugogo, NJira, additional, Jain, Neal, additional, Sher, Lawrence D, additional, Andrawis, Nabil S, additional, Fuentes, David, additional, Boren, Eric Jason, additional, Gonzalez, Erika G, additional, Talreja, Neetu, additional, Durrani, Sheharyar Sandy, additional, Sekhsaria, Sudhir, additional, DeLeon, Samuel, additional, Shukla, Mayank, additional, Totszollosy Tarpay, Martha M, additional, Fakih, Faisal, additional, Hudes, Golda, additional, Tillinghast, Jeffrey P, additional, Korenblat, Phillip E, additional, Shenoy, Kartik, additional, Que, Loretta, additional, Kureishy, Shahrukh Ahmad, additional, Umeh, Fred Chukwuemeka, additional, Nguyen, Vinh Nhu, additional, Chu, Hanh Thi, additional, and Nguyen, Thuy Thi Dieu, additional
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- 2023
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123. Is the 2013 American Thoracic Society CPAP-tracking system algorithm useful for managing non-adherence in long-term CPAP-treated patients?
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Rotty, Marie-Caroline, Mallet, Jean-Pierre, Suehs, Carey M., Martinez, Christian, Borel, Jean-Christian, Rabec, Claudio, Bourdin, Arnaud, Molinari, Nicolas, and Jaffuel, Dany
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- 2019
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124. Observational UK cohort study to describe intermittent oral corticosteroid prescribing patterns and their association with adverse outcomes in asthma.
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Heatley, Heath, Tran, Trung N., Bourdin, Arnaud, Menzies-Gow, Andrew, Jackson, David J., Maslova, Ekaterina, Chapaneri, Jatin, Skinner, Derek, Carter, Victoria, Kai Chan, Jeffrey Shi, Ariti, Con, Haughney, John, and Price, David B.
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EXOTROPIA ,WHEEZE ,INAPPROPRIATE prescribing (Medicine) ,ORAL medication ,ASTHMA ,COHORT analysis - Published
- 2023
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125. Persistent severe hypereosinophilic asthma is not associated with airway remodeling
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Alagha, Khuder, Jarjour, Baihas, Bommart, Sebastien, Aviles, Berta, Varrin, Muriel, Gamez, Anne Sophie, Molinari, Nicolas, Vachier, Isabelle, Paganin, Fabrice, Chanez, Pascal, and Bourdin, Arnaud
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- 2015
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126. Observational UK cohort study to describe intermittent oral corticosteroid prescribing patterns and their association with adverse outcomes in asthma
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Heatley, Heath, primary, Tran, Trung N, additional, Bourdin, Arnaud, additional, Menzies-Gow, Andrew, additional, Jackson, David J, additional, Maslova, Ekaterina, additional, Chapaneri, Jatin, additional, Skinner, Derek, additional, Carter, Victoria, additional, Chan, Jeffrey Shi Kai, additional, Ariti, Con, additional, Haughney, John, additional, and Price, David B, additional
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- 2022
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127. Identifying and appraising outcome measures for severe asthma: a systematic review
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Rattu, Anna, primary, Khaleva, Ekaterina, additional, Brightling, Chris, additional, Dahlén, Sven-Erik, additional, Bossios, Apostolos, additional, Fleming, Louise, additional, Chung, Kian Fan, additional, Melén, Erik, additional, Djukanovic, Ratko, additional, Chaudhuri, Rekha, additional, Exley, Andrew, additional, Koppelman, Gerard H., additional, Bourdin, Arnaud, additional, Rusconi, Franca, additional, Porsbjerg, Celeste, additional, Coleman, Courtney, additional, Williams, Clare, additional, Nielsen, Hanna, additional, Davin, Elizabeth, additional, Taverner, Phil, additional, Romagosa Vilarnau, Sofia, additional, and Roberts, Graham, additional
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- 2022
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128. Cytokines as prognostic biomarkers in pulmonary arterial hypertension
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Boucly, Athénaïs, primary, Tu, Ly, additional, Guignabert, Christophe, additional, Rhodes, Christopher, additional, De Groote, Pascal, additional, Prévot, Grégoire, additional, Bergot, Emmanuel, additional, Bourdin, Arnaud, additional, Beurnier, Antoine, additional, Roche, Anne, additional, Jevnikar, Mitja, additional, Jaïs, Xavier, additional, Montani, David, additional, Wilkins, Martin R., additional, Humbert, Marc, additional, Sitbon, Olivier, additional, and Savale, Laurent, additional
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- 2022
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129. Dupilumab sustains efficacy in patients with moderate-to-severe type 2 asthma regardless of ICS dose
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Pavord, Ian, primary, Bourdin, Arnaud, additional, Papi, Alberto, additional, domingo, christian, additional, Corren, Jonathan, additional, Altincatal, Arman, additional, Radwan, Amr, additional, Pandit-Abid, Nami, additional, Jacob-Nara, Juby A., additional, Deniz, Yamo, additional, Rowe, Paul, additional, Laws, Elizabeth, additional, J, David Lederer, additional, and Hardin, Megan, additional
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- 2022
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130. Proactive Risk Management: A Novel Approach to Embedding Oral Corticosteroid Stewardship into Asthma Care
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Price, David, primary and Bourdin, Arnaud, additional
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- 2022
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131. Mucus from human bronchial epithelial cultures: rheology and adhesion across length scales
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Jory, Myriam, primary, Donnarumma, Dario, additional, Blanc, Christophe, additional, Bellouma, Karim, additional, Fort, Aurélie, additional, Vachier, Isabelle, additional, Casanellas, Laura, additional, Bourdin, Arnaud, additional, and Massiera, Gladys, additional
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- 2022
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132. Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in severe asthma patients eligible for both
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Price, David, primary, pfeffer, paul, additional, Ali, Nasloon, additional, Murray, Ruth, additional, Ulrik, Charlotte, additional, Tran, Trung, additional, Maspero, Jorge, additional, Peters, Matthew, additional, Christoff, George, additional, Sadatsafavi, Mohsen, additional, Torres-Duque, Carlos A., additional, Altraja, Alan, additional, Lehtimäki, Lauri, additional, Papadopoulos, Nikolaos, additional, Salvi, Sundeep, additional, Costello, Richard W., additional, Cushen, Breda, additional, Heffler, Enrico, additional, Iwanaga, Takashi, additional, Al-Ahmad, Mona, additional, Larenas-Linnemann, Désirée, additional, Kuna, Piotr, additional, Fonseca, João, additional, Al-Lehebi, Riyad, additional, Rhee, Chin Kook, additional, Llano, Luis Perez de, additional, Perng, Diahn-Wang, additional, Mahboub, Bassam, additional, Wang, Eileen, additional, Goh, Yun Yi Celine, additional, Lyu, Juntao, additional, Newell, Anthony, additional, Alacqua, Marianna, additional, Bhutani, Mohit, additional, Bjermer, Leif, additional, Björnsdóttir, Unnur Steina, additional, Bourdin, Arnaud, additional, Bülow, Anna Von, additional, Busby, John, additional, Canonica, Walter, additional, Cosio, Borja G, additional, Dorscheid, Delbert, additional, Esquerre, Mariana Muñoz, additional, FitzGerald, Mark, additional, Gil, Esther Garcia, additional, Gibson, Peter Gerard, additional, Heaney, Liam, additional, Hew, Mark, additional, Hilberg, Ole, additional, Hoyte, Flavia, additional, Jackson, David, additional, Koh, Mariko, additional, Ko, Hsin-Kuo, additional, Lee, Jae Ha, additional, Lehmann, Sverre, additional, Loureiro, Claudia Chaves, additional, Ludviksdottir, Dora, additional, Menzies-Gow, Andrew, additional, Mitchell, Patrick, additional, Papaioannou, Andriana, additional, Popov, Todor, additional, Porsbjerg, Celeste, additional, Salameh, Laila, additional, Sirena, Concetta, additional, Taillé, Camille, additional, Taube, Christian, additional, Tohda, Yuji, additional, and Wechsler, M. E., additional
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- 2022
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133. Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA)
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Khaleva, Ekaterina, primary, Rattu, Anna, additional, Brightling, Chris, additional, Bush, Andrew, additional, Bossios, Apostolos, additional, Bourdin, Arnaud, additional, Chung, Kian Fan, additional, Chaudhuri, Rekha, additional, Coleman, Courtney, additional, Dahlén, Sven-Erik, additional, Djukanovic, Ratko, additional, Deschildre, Antoine, additional, Fleming, Louise, additional, Fowler, Stephen J., additional, Gupta, Atul, additional, Hamelmann, Eckard, additional, Hashimoto, Simone, additional, Hedlin, Gunilla, additional, Koppelman, Gerard H., additional, Melén, Erik, additional, Murray, Clare S., additional, Pilette, Charles, additional, Porsbjerg, Celeste, additional, Pike, Katharine C., additional, Rusconi, Franca, additional, Williams, Clare, additional, Ahrens, Birgit, additional, Alter, Peter, additional, Anckers, Freja, additional, van den Berge, Maarten, additional, Blumchen, Katharina, additional, Brusselle, Guy, additional, Clarke, Graham W., additional, Cunoosamy, Danen, additional, Dahlén, Barbro, additional, Dixey, Piers, additional, Exley, Andrew, additional, Frey, Urs, additional, Gaillard, Erol A., additional, Giovannini-Chami, Lisa, additional, Grigg, Jonathan, additional, Hartenstein, Diana, additional, Heaney, Liam G., additional, Karadag, Bülent, additional, Kaul, Susanne, additional, Kull, Inger, additional, Licari, Amelia, additional, Maitland-van der Zee, Anke H., additional, Mahler, Vera, additional, Schoos, Ann-Marie M., additional, Nagakumar, Prasad, additional, Negus, Jenny, additional, Nielsen, Hanna, additional, Paton, James, additional, Pijnenburg, Mariëlle, additional, Ramiconi, Valeria, additional, Romagosa Vilarnau, Sofia, additional, Principe, Stefania, additional, Rutjes, Niels, additional, Saglani, Sejal, additional, Seddon, Paul, additional, Singer, Florian, additional, Staudinger, Heribert, additional, Turner, Steve, additional, Vijverberg, Susanne, additional, Winders, Tonya, additional, Yasinska, Valentyna, additional, and Roberts, Graham, additional
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- 2022
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134. CLINICAL OUTCOMES IN PATIENTS WITH SEVERE ASTHMA WHO HAD OR HAD NOT INITIATED BIOLOGIC THERAPY: RESULTS FROM THE CLEAR STUDY
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ALI, NASLOON, primary, CHEN, STEPHANIE, additional, N TRAN, TRUNG, additional, COOK, WILLIAM, additional, ALTRAJA, ALAN, additional, AB BOURDIN, ARNAUD, additional, SHEU, CHAU-CHYUN, additional, TSAI, MING-JU, additional, C HOYTE, FLAVIA, additional, R QUINTON, ANNA, additional, EMMANUEL, BENJAMIN, additional, GOH, CELINE, additional, CARTER, VICTORIA, additional, and B PRICE, DAVID, additional
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- 2022
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135. Characterization of Patients in the International Severe Asthma Registry with High Steroid Exposure Who Did or Did Not Initiate Biologic Therapy
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Chen, Wenjia, primary, Sadatsafavi, Mohsen, additional, Tran, Trung N, additional, Murray, Ruth B, additional, Wong, Chong Boon Nigel, additional, Ali, Nasloon, additional, Ariti, Cono, additional, Garcia Gil, Esther, additional, Newell, Anthony, additional, Alacqua, Marianna, additional, Al-Ahmad, Mona, additional, Altraja, Alan, additional, Al-Lehebi, Riyad, additional, Bhutani, Mohit, additional, Bjermer, Leif, additional, Bjerrum, Anne Sofie, additional, Bourdin, Arnaud, additional, Bulathsinhala, Lakmini, additional, von Bülow, Anna, additional, Busby, John, additional, Canonica, Giorgio Walter, additional, Carter, Victoria, additional, Christoff, George C, additional, Cosio, Borja G, additional, Costello, Richard W, additional, FitzGerald, J Mark, additional, Fonseca, João A, additional, Yoo, Kwang Ha, additional, Heaney, Liam G, additional, Heffler, Enrico, additional, Hew, Mark, additional, Hilberg, Ole, additional, Hoyte, Flavia, additional, Iwanaga, Takashi, additional, Jackson, David J, additional, Jones, Rupert C, additional, Koh, Mariko Siyue, additional, Kuna, Piotr, additional, Larenas-Linnemann, Désirée, additional, Lehmann, Sverre, additional, Lehtimäki, Lauri A, additional, Lyu, Juntao, additional, Mahboub, Bassam, additional, Maspero, Jorge, additional, Menzies-Gow, Andrew N, additional, Sirena, Concetta, additional, Papadopoulos, Nikolaos, additional, Papaioannou, Andriana I, additional, Pérez de Llano, Luis, additional, Perng, Diahn-Warng, additional, Peters, Matthew, additional, Pfeffer, Paul E, additional, Porsbjerg, Celeste M, additional, Popov, Todor A, additional, Rhee, Chin Kook, additional, Salvi, Sundeep, additional, Taillé, Camille, additional, Taube, Christian, additional, Torres-Duque, Carlos A, additional, Ulrik, Charlotte S, additional, Ra, Seung Won, additional, Wang, Eileen, additional, Wechsler, Michael E, additional, and Price, David B, additional
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- 2022
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136. CLINICAL OUTCOMES AND EMERGENCY HEALTH CARE UTILIZATION IN PATIENTS WITH SEVERE ASTHMA WHO CONTINUED, SWITCHED, OR STOPPED BIOLOGIC THERAPY: RESULTS FROM THE CLEAR STUDY
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ALI, NASLOON, primary, CHEN, STEPHANIE, additional, N TRAN, TRUNG, additional, COOK, WILLIAM, additional, ALTRAJA, ALAN, additional, AB BOURDIN, ARNAUD, additional, SHEU, CHAU-CHYUN, additional, TSAI, MING-JU, additional, C HOYTE, FLAVIA, additional, R QUINTON, ANNA, additional, EMMANUEL, BENJAMIN, additional, GOH, CELINE, additional, CARTER, VICTORIA, additional, and B PRICE, DAVID, additional
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- 2022
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137. Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA)
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Khaleva, Ekaterina, Rattu, Anna, Brightling, Chris, Bush, Andrew, Bossios, Apostolos, Bourdin, Arnaud, Chung, Kian Fan, Chaudhuri, Rekha, Coleman, Courtney, Dahlén, Sven-Erik, Djukanovic, Ratko, Deschildre, Antoine, Fleming, Louise, Fowler, Stephen J, Gupta, Atul, Hamelmann, Eckard, Hashimoto, Simone, Hedlin, Gunilla, Koppelman, Gerard H, Melén, Erik, Murray, Clare S, Pilette, Charles, Porsbjerg, Celeste, Pike, Katharine C, Rusconi, Franca, Williams, Clare, Ahrens, Birgit, Alter, Peter, Anckers, Freja, van den Berge, Maarten, Blumchen, Katharina, Brusselle, Guy, Clarke, Graham W, Cunoosamy, Danen, Dahlén, Barbro, Dixey, Piers, Exley, Andrew, Frey, Urs, Gaillard, Erol A, Giovannini-Chami, Lisa, Grigg, Jonathan, Hartenstein, Diana, Heaney, Liam G, Karadag, Bülent, Kaul, Susanne, Kull, Inger, Licari, Amelia, Maitland-van der Zee, Anke H, Mahler, Vera, and Roberts, Graham
- Abstract
BACKGROUND: Effectiveness studies with biological therapies for asthma lack standardised outcome measures. The COMSA (Core Outcome Measures sets for paediatric and adult Severe Asthma) working group sought to develop Core Outcome Measures (COM) sets to facilitate better synthesis of data and appraisal of biologics in paediatric and adult asthma clinical studies.METHODS: COMSA utilised a multi-stakeholder consensus process among patients with severe asthma, adult, and paediatric clinicians, pharmaceutical representatives and health regulators from across Europe. Evidence included a systematic review of development, validity, and reliability of selected outcome measures plus a narrative review and a pan-European survey to better understand patients' and carers' views about outcome measures. It was discussed using a modified GRADE Evidence to Decision framework. Anonymous voting was conducted using predefined consensus criteria.RESULTS: Both adult and paediatric COM sets include forced expiratory volume in 1 s (FEV1) as z scores, annual frequency of severe exacerbations and maintenance oral corticosteroid use. Additionally, the paediatric COM set includes the Paediatric Asthma Quality of Life Questionnaire, and Asthma Control Test (ACT) or Childhood-ACT while the adult COM includes the Severe Asthma Questionnaire and the Asthma Control Questionnaire-6 (symptoms and rescue medication use reported separately).CONCLUSIONS: This patient-centred collaboration has produced two COM sets for paediatric and adult severe asthma. It is expected that they will inform the methodology of future clinical trials, enhance comparability of efficacy and effectiveness of biological therapies, and help assess their socioeconomic value. COMSA will inform definitions of non-response and response to biological therapy for severe asthma.
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- 2022
138. Prognostic value of cluster analysis of severe asthma phenotypes
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Bourdin, Arnaud, Molinari, Nicolas, Vachier, Isabelle, Varrin, Muriel, Marin, Grégory, Gamez, Anne-Sophie, Paganin, Fabrice, and Chanez, Pascal
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- 2014
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139. OCS Tapering Delphi
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Suehs, Carey, Price, David, Menzies-gow, Andrew, Canonica, Giorgio, Gurnell, Mark, and Bourdin, Arnaud
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stomatognathic diseases ,immune system diseases ,education ,hormones, hormone substitutes, and hormone antagonists ,respiratory tract diseases - Abstract
Expert statements concerning the tapering of oral corticosteroids (OCS) for the treatment of asthma
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- 2022
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140. Recommandations pratiques pour le diagnostic et la prise en charge de la fibrose pulmonaire idiopathique – Actualisation 2021. Version intégrale
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Cottin, Vincent, Bonniaud, Philippe, Cadranel, Jacques, Crestani, Bruno, Jouneau, Stéphane, Marchand-Adam, Sylvain, Nunes, Hilario, Wémeau-Stervinou, Lidwine, Bergot, Emmanuel, Blanchard, Elodie, Borie, Raphaël, Bourdin, Arnaud, Chenivesse, Cécile, Clément, Annick, Gomez, Emmanuel, Gondouin, Anne, Hirschi, Sandrine, Lebargy, François, Marquette, Charles-Hugo, Montani, David, Prévot, Grégoire, Quetant, Sébastien, Reynaud-Gaubert, Martine, Salaun, Mathieu, Sanchez, Olivier, Trumbic, Bruno, Berkani, Karim, Brillet, Pierre-Yves, Campana, Marion, Chalabreysse, Lara, Chatté, Gérard, Debieuvre, Didier, Ferretti, Gilbert, Fourrier, Jean-Michel, Just, Nicolas, Kambouchner, Marianne, Legrand, Bertrand, Le Guillou, Frédéric, Lhuillier, Jean-Pierre, Mehdaoui, Anas, Naccache, Jean-Marc, Paganon, Catherine, Rémy-Jardin, Martine, Si-Mohamed, Salim, Terrioux, Philippe, Infections Virales et Pathologie Comparée - UMR 754 (IVPC), École Pratique des Hautes Études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre national de référence des maladies pulmonaires rares [Lyon] (CRMPM), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Service de Pneumologie Soins Intensifs, Appareillage Respiratoire [CHU de Dijon], CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École des Hautes Études en Santé Publique [EHESP] (EHESP), Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Hôpital Avicenne [AP-HP], Institut Coeur Poumon [CHU Lille], Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), CHU Pessac, Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Maladies génétiques d'expression pédiatrique (U933), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Nouvel Hôpital Civil de Strasbourg, Centre Hospitalier Universitaire de Reims (CHU Reims), Hôpital Pasteur [Nice] (CHU), Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Hypertension arterielle pulmonaire physiopathologie et innovation thérapeutique, Centre Chirurgical Marie Lannelongue (CCML)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Universitaire [Grenoble] (CHU), CHU Marseille, Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes (LITIS), Université Le Havre Normandie (ULH), Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA), Centre d'Investigation Clinique [CHU Rouen] (CIC Rouen), Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Hypoxie et Poumon : pneumopathologies fibrosantes, modulations ventilatoires et circulatoires (H&P), UFR SMBH-Université Sorbonne Paris Nord, Centre Hospitalier Régional d'Orléans (CHRO), Hospices Civils de Lyon (HCL), Centre Hospitalier Emile Muller [Mulhouse] (CH E.Muller Mulhouse), Groupe Hospitalier de Territoire Haute Alsace (GHTHA), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre Hospitalier Eure-Seine - Hôpital d'Evreux - Vernon (Evreux), Groupe Hospitalier Paris Saint-Joseph (hpsj), Services de Pneumologie, Exploration Fonctionnelle Respiratoire et Cardiologie (Hôpital Louis Pradel), Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Association pour l’amélioration de la prise en charge des maladies pulmonaires rares, Hospices Civils de Lyon, and Université Claude Bernard Lyon 1.
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Biopsy ,Biopsie ,[SDV]Life Sciences [q-bio] ,Fibrose pulmonaire ,Pneumopathie interstitielle commune ,Interstitial lung disease ,Common interstitial lung disease ,Pneumopathie interstitielle diffuse ,Pulmonary fibrosis - Abstract
National audience; BACKGROUND: Since the previous French guidelines were published in 2017, substantial additional knowledge about idiopathic pulmonary fibrosis has accumulated. METHODS: Under the auspices of the French-speaking Learned Society of Pulmonology and at the initiative of the coordinating reference center, practical guidelines for treatment of rare pulmonary diseases have been established. They were elaborated by groups of writers, reviewers and coordinators with the help of the OrphaLung network, as well as pulmonologists with varying practice modalities, radiologists, pathologists, a general practitioner, a head nurse, and a patients’ association. The method was developed according to rules entitled "Good clinical practice" in the overall framework of the "Guidelines for clinical practice" of the official French health authority (HAS), taking into account the results of an online vote using a Likert scale. RESULTS: After analysis of the literature, 54 recommendations were formulated, improved, and validated by the working groups. The recommendations covered a wide-ranging aspects of the disease and its treatment: epidemiology, diagnostic modalities, quality criteria and interpretation of chest CT, indication and modalities of lung biopsy, etiologic workup, approach to familial disease entailing indications and modalities of genetic testing, evaluation of possible functional impairments and prognosis, indications for and use of antifibrotic therapy, lung transplantation, symptom management, comorbidities and complications, treatment of chronic respiratory failure, diagnosis and management of acute exacerbations of fibrosis. CONCLUSION: These evidence-based guidelines are aimed at guiding the diagnosis and the management in clinical practice of idiopathic pulmonary fibrosis.; Contexte :Depuis les précédentes recommandations françaises publiées en 2017, les connaissances concernant la fibrose pulmonaire idiopathique ont évolué sur de nombreux aspects.Méthodes :Des recommandations pratiques ont été établies à l’initiative du Centre coordonnateur de référence des maladies pulmonaires rares, sous l’égide de la Société de Pneumologie de Langue Française, par un groupe de coordination, un groupe de rédaction, et un groupe de lecture, impliquant l’ensemble du réseau OrphaLung, des pneumologues de divers modes d’exercice, des radiologues, des pathologistes, un médecin généraliste, un cadre de santé, et une association de patients. La méthode a respecté les règles d’élaboration des « Bonnes pratiques cliniques » selon la méthode des « Recommandations pour la pratique clinique » de la Haute Autorité de Santé, incluant un vote en ligne selon une échelle Likert.Résultats :Après une analyse bibliographique, 54 recommandations ont été formulées, améliorées, puis validées par les groupes de travail, portant sur des aspects multiples de la maladie : épidémiologie, modalités diagnostiques, critères de qualité et interprétation du scanner thoracique, indication et réalisation de la biopsie pulmonaire, bilan étiologique, modalités et indications de l’enquête familiale et de l’analyse génétique, évaluation du retentissement fonctionnel et du pronostic, indication et emploi des médicaments antifibrosants, transplantation pulmonaire, prise en charge des symptômes, comorbidités et complications, traitement de l’insuffisance respiratoire chronique, diagnostic et prise en charge des exacerbations aiguës de fibrose.Conclusion :Ces recommandations fondées sur les preuves sont destinées à guider le diagnostic et la prise en charge pratique de la fibrose pulmonaire idiopathique.
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141. Empty outcome table
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Suehs, Carey, Bourdin, Arnaud, Nicolas, Audrey, Martinez, Aurelie, Molinari, Nicolas, and Vachier, Isabelle
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- 2022
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142. Resala
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Suehs, Carey, Nogué, Erika, Malafaye, Nicolas, Bourdin, Arnaud, and Molinari, Nicolas
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health resource use ,Nucala ,drug consumption ,cost ,Medicine and Health Sciences ,mepolizumab ,biologics ,France ,immunotherapy ,price - Abstract
Health resource usage associated with the first year of mepolizumab
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143. CLIPPCAIR
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Bommart, Sébastien, Suehs, Carey, Marty-Ané, Charles, Vachier, Isabelle, Charriot, Jeremy, Hrieche, Kheira, Solovei, Laurence, Hayot, Maurice, Gouzi, Fares, Serre, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud
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Medicine and Health Sciences - Abstract
The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be based on data derived from a thoracic CT scan with injection of contrast media. This registration includes information contained in the eCRF.
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144. Brainstorming rounds
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Suehs, Carey, Vachier, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud
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145. CortiCORONA
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Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, Suehs, Carey, and Molinari, Nicolas
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body regions ,viruses ,fungi ,Medicine and Health Sciences ,skin and connective tissue diseases ,respiratory tract diseases - Abstract
Determination of biomarkers to predict the response to treatment with dexamethasone for Sars-Cov(2 / COVID-19 pneumonia
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146. Public protocol
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Suehs, Carey and Bourdin, Arnaud
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Delphi consensus ,tapering ,protocol ,corticosteroids - Published
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147. Initial demographic and opinion questionnaire
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Suehs, Carey, Vachier, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud
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148. eo-Delphi
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Suehs, Carey, Vachier, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud
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eo-Delphi aims to create consensus for a core set of outcomes for the eo-Drive protocol using a modified Delphi method.
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149. Ranking rounds
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Suehs, Carey, Vachier, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud
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150. Protocol
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Suehs, Carey, Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, and Molinari, Nicolas
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- 2022
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