363 results on '"Brian Anderson"'
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102. Updated inventory of glacier ice in New Zealand based on 2016 satellite imagery
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Heather Purdie, Trevor Chinn, Brian Anderson, S. Baumann, Andrew Lorrey, Andrew Mackintosh, Wolfgang Rack, Shaun R. Eaves, and Catherine Collier
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geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,% area reduction ,Glacier ,010502 geochemistry & geophysics ,Maximum likelihood classification ,01 natural sciences ,ddc ,Aerial photography ,Remote sensing (archaeology) ,Satellite data ,Satellite imagery ,Physical geography ,Band ratio ,Geology ,0105 earth and related environmental sciences ,Earth-Surface Processes - Abstract
The only complete inventory of New Zealand glaciers was based on aerial photography starting in 1978. While there have been partial updates using 2002 and 2009 satellite data, most glaciers are still represented by the 1978 outlines in contemporary global glacier databases. The objective of this project is to establish an updated glacier inventory for New Zealand. We have used Landsat 8 OLI satellite imagery from February and March 2016 for delineating clean glaciers using a semi-automatic band ratio method and debris-covered glaciers using a maximum likelihood classification. The outlines have been checked against Sentinel-2 MSI data, which have a higher resolution. Manual post processing was necessary due to misclassifications (e.g. lakes, clouds), mapping in shadowed areas, and combining the clean and debris-covered parts into single glaciers. New Zealand glaciers cover an area of 794 ± 34 km2 in 2016 with a debris-covered area of 10%. Of the 2918 glaciers, seven glaciers are >10 km2 while 71% is 2. The debris cover on those largest glaciers is >40%. Only 15 glaciers are located on the North Island. For a selection of glaciers, we were able to calculate the area reduction between the 1978 and 2016 inventories.
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- 2021
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103. The Last Glacial Maximum in the central North Island, New Zealand: Palaeoclimate inferences from glacier modelling
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AT Calvert, GS Leonard, JM Schaefer, G Winckler, CE Conway, DB Townsend, AM Doughty, Brian Anderson, AN Mackintosh, and Shaun Eaves
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© Author(s) 2016. Quantitative palaeoclimate reconstructions provide data for evaluating the mechanisms of past, natural climate variability. Geometries of former mountain glaciers, constrained by moraine mapping, afford the opportunity to reconstruct palaeoclimate, due to the close relationship between ice extent and local climate. In this study, we present results from a series of experiments using a 2-D coupled energy balance-ice flow model that investigate the palaeoclimate significance of Last Glacial Maximum moraines within nine catchments in the central North Island, New Zealand. We find that the former ice limits can be simulated when present-day temperatures are reduced by between 4 and 7°C, if precipitation remains unchanged from present. The spread in the results between the nine catchments is likely to represent the combination of chronological and model uncertainties. The majority of catchments targeted require temperature decreases of 5.1 to 6.3°C to simulate the former glaciers, which represents our best estimate of the temperature anomaly in the central North Island, New Zealand, during the Last Glacial Maximum. A decrease in precipitation of up to 25% from present, as suggested by proxy evidence and climate models, increases the magnitude of the required temperature changes by up to 0.8°C. Glacier model experiments using reconstructed topographies that exclude the volume of post-glacial (< 15 ka) volcanism generally increased the magnitude of cooling required to simulate the former ice limits by up to 0.5°C. Our palaeotemperature estimates expand the spatial coverage of proxy-based quantitative palaeoclimate reconstructions in New Zealand. Our results are also consistent with independent, proximal temperature reconstructions from fossil groundwater and pollen assemblages, as well as similar glacier modelling reconstructions from the central Southern Alps, which suggest air temperatures were ca. 6°C lower than present across New Zealand during the Last Glacial Maximum.
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- 2021
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104. Risk Factors for and Rate of Development of Venous Thromboembolism in Lateral Skull Base Surgery
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Brian Anderson
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medicine.medical_specialty ,Rate of development ,business.industry ,Skull base surgery ,medicine ,business ,Venous thromboembolism ,Surgery - Published
- 2021
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105. Risk Factors Associated with Necessity for Intensive Care Utilization in Lateral Skull Base Surgery
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Pedrom C. Sioshansi, Katrina Minutello, Brian Anderson, Seilesh C. Babu, and Robert M. Conway
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medicine.medical_specialty ,business.industry ,Intensive care ,Skull base surgery ,medicine ,Intensive care medicine ,business - Published
- 2021
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106. Peptide ELISA and FRET-qPCR Identified a Significantly Higher Prevalence of Chlamydia suis in Domestic Pigs Than in Feral Swine from the State of Alabama, USA
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Subarna Barua, Constantinos S. Kyriakis, Bernhard Kaltenboeck, Steven Kitchens, Stuart Price, Brian Anderson, Folasade Adekanmbi, Monirul Hoque, Steven Madere, Vienna R. Brown, Virginia Aida, Chengming Wang, B. Graeme Lockaby, Anwar Kalalah, Sara Bolds, Kh. Shamsur Rahman, and Anil Poudel
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Microbiology (medical) ,animal diseases ,lcsh:Medicine ,Biology ,Microbiology ,feral swine ,Chlamydia suis ,medicine ,Immunology and Allergy ,Typing ,Molecular Biology ,Pathogen ,Feces ,USA ,Genetic diversity ,Chlamydia ,General Immunology and Microbiology ,lcsh:R ,medicine.disease ,biology.organism_classification ,Infectious Diseases ,PCR ,biology.protein ,Multilocus sequence typing ,Antibody ,peptide ELISA ,human activities - Abstract
Chlamydia suis is an important, highly prevalent, and diverse obligate intracellular pathogen infecting pigs. In order to investigate the prevalence and diversity of C. suis in the U.S., 276 whole blood samples from feral swine were collected as well as 109 fecal swabs and 60 whole blood samples from domestic pigs. C. suis-specific peptide ELISA identified anti-C. suis antibodies in 13.0% of the blood of feral swine (26/276) and 80.0% of the domestic pigs (48/60). FRET-qPCR and DNA sequencing found C. suis DNA in 99.1% of the fecal swabs (108/109) and 21.7% of the whole blood (13/60) of the domestic pigs, but not in any of the assayed blood samples (0/267) in feral swine. Phylogenetic comparison of partial C. suis ompA gene sequences and C. suis-specific multilocus sequencing typing (MLST) revealed significant genetic diversity of the C. suis identified in this study. Highly genetically diverse C. suis strains are prevalent in domestic pigs in the USA. As crowding strongly enhances the frequency and intensity of highly prevalent Chlamydia infections in animals, less population density in feral swine than in domestic pigs may explain the significantly lower C. suis prevalence in feral swine. A future study is warranted to obtain C. suis DNA from feral swine to perform genetic diversity of C. suis between commercial and feral pigs.
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- 2020
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107. Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis
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Gabriel Courties, Jazz Munitz, Matthias Nahrendorf, Giuseppe Carlucci, D. Michael Tillson, Edmund J. Keliher, Filip K. Swirski, Gregory R. Wojtkiewicz, Yoshiko Iwamoto, Marvin Krohn-Grimberghe, Sharron Barney, Paul H. Walz, Willem J. M. Mulder, Mandy M. T. van Leent, Charlotte G. Muse, Kay P. Riddell, William R. Church, Yohana C. Toner, Georgios Soultanidis, Anu E. Meerwaldt, Vanessa Frodermann, Glenn Horne, Claudia Calcagno, Jana Grune, Yu Xiang Ye, Paul E. Bock, Ashoka Maddur-Appajaiah, Peter Panizzi, Kaitlyn Bushey, Alexander Maier, Ingrid M. Verhamme, Carlos Pérez-Medina, Yuan Sun, Brian Anderson, Precision Medicine, ICMS Core, Amsterdam Cardiovascular Sciences, ACS - Atherosclerosis & ischemic syndromes, Graduate School, and AII - Infectious diseases
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0301 basic medicine ,Innate immune system ,business.industry ,medicine.drug_class ,medicine.medical_treatment ,Antibiotics ,General Medicine ,Immunotherapy ,030204 cardiovascular system & hematology ,medicine.disease_cause ,medicine.disease ,SDG 3 – Goede gezondheid en welzijn ,Staphylocoagulase ,Microbiology ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Immune system ,SDG 3 - Good Health and Well-being ,Staphylococcus aureus ,Medicine ,Endocarditis ,business ,Preclinical imaging - Abstract
Acute bacterial endocarditis is a rapid, difficult to manage, and frequently lethal disease. Potent antibiotics often cannot efficiently kill Staphylococcus aureus that colonizes the heart’s valves. S. aureus relies on virulence factors to evade therapeutics and the host’s immune response, usurping the host’s clotting system by activating circulating prothrombin with staphylocoagulase and von Willebrand factor–binding protein. An insoluble fibrin barrier then forms around the bacterial colony, shielding the pathogen from immune cell clearance. Targeting virulence factors may provide previously unidentified avenues to better diagnose and treat endocarditis. To tap into this unused therapeutic opportunity, we codeveloped therapeutics and multimodal molecular imaging to probe the host-pathogen interface. We introduced and validated a family of small-molecule optical and positron emission tomography (PET) reporters targeting active thrombin in the fibrin-rich environment of bacterial colonies. The imaging agents, based on the clinical thrombin inhibitor dabigatran, are bound to heart valve vegetations in mice. Using optical imaging, we monitored therapy with antibodies neutralizing staphylocoagulase and von Willebrand factor–binding protein in mice with S. aureus endocarditis. This treatment deactivated bacterial defenses against innate immune cells, decreased in vivo imaging signal, and improved survival. Aortic or tricuspid S. aureus endocarditis in piglets was also successfully imaged with clinical PET/magnetic resonance imaging. Our data map a route toward adjuvant immunotherapy for endocarditis and provide efficient tools to monitor this drug class for infectious diseases.
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- 2020
108. Magnetic evidence for an extended hydrogen exosphere at Mercury
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Daniel Schmid, Wolfgang Baumjohann, Helmut Lammer, Nikolay Erkaev, Yasuhito Narita, Ferdinand Plaschke, Martin Volwerk, and Brian Anderson
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Hydrogen ,Chemistry ,Inorganic chemistry ,chemistry.chemical_element ,Exosphere ,Mercury (element) - Abstract
Remote sensing observations of the Mariner 10 and MESSENGER spacecraft have shown the existence of atomic (H) and molecular (H2) hydrogen in the exosphere around Mercury. However, to date the hydrogen number densities could only be estimated indirectly from exospheric models, based on Lyman-α radiances for H and the H2 detection threshold of the Mariner 10 occultation experiment. Here we show the first in-situ measured altitude-density profile of atomic H, derived from magnetic field observations by MESSENGER. Our results reveal an extended H corona with densities decreasing from 1000 − 100 cm−3 between 2 − 8 Mercury radii. These densities are 2-3 orders of magnitude larger than previously predicted, but in good agreement with the Lyman-α radiances. The large H densities result from the dissociation of H2. We can reproduce the observed H densities using an exospheric model which includes ionization, dissociation and recombination, that allows us to constrain the H2 surface density to ∼ 5×10^5 cm−3. This is two orders of magnitude smaller than the previously assumed upper limit.
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- 2020
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109. A Simple Educational Wind Tunnel Setup For Visualization Of Duct Flow Streamlines And Nozzle/Diffuser Boundary Layer Separation
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B. Terry Beck, Brian Anderson, and Mina Hosni
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- 2020
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110. Optimization Problems for All Levels
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Brian Anderson, Robin Hissam, Joseph Shaeiwitz, and Richard Turton
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- 2020
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111. The Wind Tunnel As A Practical Tool For The Demonstration Of Engineering Fluid Mechanics And Principles Of Aerodynamic Design
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B. Terry Beck and Brian Anderson
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- 2020
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112. Review for 'Stress fracture of the palmar, distal cortex of the third metacarpal bone: A diagnostic challenge with a good prognosis'
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Brian Anderson
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Stress (mechanics) ,medicine.anatomical_structure ,business.industry ,Cortex (anatomy) ,medicine ,Third metacarpal bone ,Fracture (geology) ,Good prognosis ,Anatomy ,business - Published
- 2020
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113. The electronic health record as a clinical trials tool: Opportunities and challenges
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Brian Anderson, Steven Piantadosi, Monica M. Bertagnolli, and Andre Quina
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Biomedical Research ,Computer science ,media_common.quotation_subject ,01 natural sciences ,010104 statistics & probability ,03 medical and health sciences ,0302 clinical medicine ,Electronic health record ,Health care ,Electronic Health Records ,Humans ,Quality (business) ,030212 general & internal medicine ,0101 mathematics ,Data reporting ,media_common ,Randomized Controlled Trials as Topic ,Pharmacology ,Data collection ,business.industry ,Data Collection ,General Medicine ,Data structure ,Data science ,Clinical trial ,Clinical research ,Research Design ,business ,Delivery of Health Care - Abstract
Clinical trials provide evidence essential for progress in health care, and as the complexity of medical care has increased, the demand for such data has dramatically expanded. Conducting clinical trials has also become more complicated, evolving to meet increasing challenges in delivering clinical care and meeting regulatory requirements. Despite this, the general approach to data collection remains the same, requiring that researchers submit clinical data in response to study treatment protocols, using precisely defined data structures made available in study-specific case report forms. Currently, research data management is not integrated within the patient’s clinical care record, creating added burden for clinical staff and opportunities for error. During the past decade, the electronic health record has become standard across the US healthcare system and is increasingly used to collect and analyze data reporting quality metrics for clinical care delivery. Recently, electronic health record data have also been used to address clinical research questions; however, this approach has significant drawbacks due to the unstructured and incomplete nature of current electronic health record data. This report describes steps necessary to use the electronic health record as a tool for conducting high-quality clinical research.
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- 2020
114. Partitioning the Uncertainty of Ensemble Projections of Global Glacier Mass Change
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Brian Anderson, Jan Hendrik Malles, Andrew Bliss, Walter W. Immerzeel, Fabien Maussion, Philip Kraaijenbrink, Ben Marzeion, Akiko Sakai, Harry Zekollari, Nicolas Champollion, Sarah Shannon, David R. Rounce, Roderik S. W. van de Wal, Matthias Huss, Regine Hock, Koji Fujita, and Valentina Radić
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Current (stream) ,geography ,geography.geographical_feature_category ,General Circulation Model ,Climatology ,Range (statistics) ,Environmental science ,Glacier ,Representative Concentration Pathways ,Natural variability ,Scale (map) ,Sea level - Abstract
Glacier mass loss is recognized as a significant contributor to current sea-level rise. However, large uncertainties remain in projections of glacier mass loss on global and regional scales. We present an ensemble of 279 global-scale glacier mass and area change projections for the 21st century based on eleven glacier models using up to ten General Circulation Models (GCMs) and four Representative Concentration Pathways (RCPs) as boundary conditions. We partition the total uncertainty into the individual contributions caused by glacier models, GCMs, RCPs, and natural variability. We find that emission scenario uncertainty is growing throughout the 21st century, and is the largest source of uncertainty by 2100. The relative importance of glacier model uncertainty decreases over time, but it is the greatest source of uncertainty until the middle of this century. The projection uncertainty associated with natural variability is small on the global scale but has strong effects on small regional scales. The projected global mass loss by 2100 relative to 2015 (75±64 mm sea-level equivalent (SLE) for RCP2.6, 165±98 mm SLE for RCP8.5) is lower than, but within the uncertainty range of previous projections.
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- 2020
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115. Conductance in the Aurora: Influence of Magnetospheric Contributors
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Agnit Mukhopadhyay, Daniel Welling, Meghan Burleigh, Aaron Ridley, Michael Liemohn, Brian Anderson, and Jesper Gjerloev
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- 2020
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116. Quality of life after pharmacomechanical catheter-directed thrombolysis for proximal deep vein thrombosis
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Susan R. Kahn, Jim A. Julian, Clive Kearon, Chu-Shu Gu, David J. Cohen, Elizabeth A. Magnuson, Anthony J. Comerota, Samuel Z. Goldhaber, Michael R. Jaff, Mahmood K. Razavi, Andrei L. Kindzelski, Joseph R. Schneider, Paul Kim, Rabih Chaer, Akhilesh K. Sista, Robert B. McLafferty, John A. Kaufman, Brandt C. Wible, Morey Blinder, Suresh Vedantham, Michael Sichlau, Athanasios Vlahos, Steven Smith, Quinn Thalheimer, Nisha Singh, Rekha Harting, John Gocke, Scott Guth, Neel Shah, Paul Brady, Marvin Schatz, Mindy Horrow, Peyman Markazi, Leli Forouzan, Terence A.S. Matalon, David Hertzog, Swapna Goday, Margaret Kennedy, Robert Kaplan, Thomas Campbell, Jamie Hartman, Elmer Nahum, Arvind Venkat, Venkataramu Krishnamurthy, John Rectenwald, Peter Henke, Jonathan Eliason, Jonathon Willatt, Guillermo Escobar, Shaun Samuels, Barry Katzen, James Benenati, Alex Powell, Constantino Pena, Howard Wallach, Ripal Gandhi, Joseph Schneider, Stanley Kim, Farrah Hashemi, Joseph Boyle, Nilesh Patel, Michael Verta, Daniel Leung, Marc Garcia, Phillip Blatt, Jamil Khatri, Dave Epstein, Randall Ryan, Tom Sweeny, Michael Stillabower, George Kimbiris, Tuhina Raman, Paul Sierzenski, Lelia Getto, Michael Dignazio, Mark Horvath, Heather Gornik, John Bartholomew, Mehdi Shishehbor, Frank Peacock, Douglas Joseph, Soo Hyum Kim, Natalia Fendrikova Mahlay, Daniel Clair, Sean Lyden, Baljendra Kapoor, Gordon McLennon, Gregory Pierce, James Newman, James Spain, Amanjiit Gill, Aaron Hamilton, Anthony Rizzo, Woosup Park, Alan Dietzek, Ira Galin, Dahlia Plummer, Richard Hsu, Patrick Broderick, Andrew Keller, Sameer Sayeed, Dennis Slater, Herb Lustberg, Jan Akus, Robert Sidman, Mandeep Dhami, Phillip Kohanski, Anca Bulgaru, Renuka Dulala, James Burch, Dinesh Kapur, Jie Yang, Mark Ranson, Alan Wladis, David Varnagy, Tarek Mekhail, Robert Winter, Manuel Perez-Izquierdo, Stephen Motew, Robin Royd-Kranis, Raymond Workman, Scott Kribbs, Gerald Hogsette, Phillip Moore, Bradley Thomason, William Means, Richard Bonsall, John Stewart, Daniel Golwya, Ezana Azene, Wayne Bottner, William Bishop, Dave Clayton, Lincoln Gundersen, Jody Riherd, Irina Shakhnovich, Kurt Ziegelbein, Thomas Chang, Karun Sharma, Sandra Allison, Fil Banovac, Emil Cohen, Brendan Furlong, Craig Kessler, Mike McCullough, Jim Spies, Judith Lin, Scott Kaatz, Todd Getzen, Joseph Miller, Scott Schwartz, Loay Kabbani, David McVinnie, John Rundback, Joseph Manno, Richard Schwab, Randolph Cole, Kevin Herman, David Singh, Ravit Barkama, Amish Patel, Anthony Comerota, John Pigott, Andrew Seiwert, Ralph Whalen, Todd Russell, Zakaria Assi, Sahira Kazanjian, Jonathan Yobbagy, Brian Kaminski, Allan Kaufman, Garett Begeman, Robert DiSalle, Subash Thakur, Marc Jacquet, Thomas Dykes, Joseph Gerding, Christopher Baker, Mark Debiasto, Derek Mittleider, George Higgins, Steven Amberson, Roger Pezzuti, Thomas Gallagher, Robert Schainfeld, Stephan Wicky, Sanjeeva Kalva, Gregory Walker, Gloria Salazar, Benjamin Pomerantz, Virenda Patel, Christopher Kabrhel, Shams Iqbal, Suvranu Gangull, Rahmi Oklu, Scott Brannan, Sanjay Misra, Haraldur Bjarnason, Aneel Ashrani, Michael Caccavale, Chad Fleming, Jeremy Friese, John Heit, Manju Kalra, Thanila Macedo, Robert McBane, Michael McKusick, Andrew Stockland, David Woodrum, Waldemar Wysokinski, Adarsh Verma, Andrew Davis, Jerry Chung, David Nicker, Brian Anderson, Robert Stein, Michael Weiss, Parag Patel, William Rilling, Sean Tutton, Robert Hieb, Eric Hohenwalter, M. Riccardo Colella, James Gosset, Sarah White, Brian Lewis, Kellie Brown, Peter Rossi, Gary Seabrook, Marcelo Guimaraes, J. Bayne Selby, William McGary, Christopher Hannegan, Jacob Robison, Thomas Brothers, Bruce Elliott, Nitin Garg, M. Bret Anderson, Renan Uflacker, Claudio Schonholz, Laurence Raney, Charles Greenberg, John Kaufman, Frederick Keller, Kenneth Kolbeck, Gregory Landry, Erica Mitchell, Robert Barton, Thomas DeLoughery, Norman Kalbfleisch, Renee Minjarez, Paul Lakin, Timothy Liem, Gregory Moneta, Khashayar Farsad, Ross Fleischman, Loren French, Vasco Marques, Yasir Al−Hassani, Asad Sawar, Frank Taylor, Rajul Patel, Rahul Malhotra, Farah Hashemi, Marvin Padnick, Melissa Gurley, Fred Cucher, Ronald Sterrenberg, G. Reshmaal Deepthi, Gomes Cumaranatunge, Sumit Bhatla, Darick Jacobs, Eric Dolen, Pablo Gamboa, L. Mark Dean, Thomas Davis, John Lippert, Sanjeev Khanna, Brian Schirf, Jeffrey Silber, Donald Wood, J. Kevin McGraw, Lucy LaPerna, Paul Willette, Timothy Murphy, Joselyn Cerezo, Rajoo Dhangana, Sun Ho Ahn, Gregory Dubel, Richard Haas, Bryan Jay, Ethan Prince, Gregory Soares, James Klinger, Robert Lambiase, Gregory Jay, Robert Tubbs, Michael Beland, Chris Hampson, Ryan O'Hara, Chad Thompson, Aaron Frodsham, Fenwick Gardiner, Abdel Jaffan, Lawrence Keating, Abdul Zafar, Radica Alicic, Rodney Raabe, Jayson Brower, David McClellan, Thomas Pellow, Christopher Zylak, Joseph Davis, M. Kathleen Reilly, Kenneth Symington, Camerson Seibold, Ryan Nachreiner, Daniel Murray, Stephen Murray, Sandeep Saha, Gregory Luna, Kim Hodgson, Robert McLafferty, Douglas Hood, Colleen Moore, David Griffen, Darren Hurst, David Lubbers, Daniel Kim, Brent Warren, Jeremy Engel, D.P. Suresh, Eric VanderWoude, Rahul Razdan, Mark Hutchins, Terry Rounsborg, Madhu Midathada, Daniel Moravec, Joni Tilford, Joni Beckman, Mahmood Razavi, Kurt Openshaw, D. Preston Flanigan, Christopher Loh, Howard Dorne, Michael Chan, Jamie Thomas, Justin Psaila, Michael Ringold, Jay Fisher, Any Lipcomb, Timothy Oskin, Brandt Wible, Brendan Coleman, David Elliott, Gary Gaddis, C. Doug Cochran, Kannan Natarajan, Stewart Bick, Jeffrey Cooke, Ann Hedderman, Anne Greist, Lorrie Miller, Brandon Martinez, Vincent Flanders, Mark Underhill, Lawrence Hofmann, Daniel Sze, William Kuo, John Louie, Gloria Hwang, David Hovsepian, Nishita Kothary, Caroline Berube, Donald Schreiber, Brooke Jeffrey, Jonathan Schor, Jonathan Deitch, Kuldeep Singh, Barry Hahn, Brahim Ardolic, Shilip Gupta, Riyaz Bashir, Angara Koneti Rao, Manish Garg, Pravin Patil, Chad Zack, Gary Cohen, Frank Schmieder, Valdimir Lakhter, David Sacks, Robert Guay, Mark Scott, Karekin Cunningham, Adam Sigal, Terrence Cescon, Nick Leasure, Thiruvenkatasamy Dhurairaj, Patrick Muck, Kurt Knochel, Joann Lohr, Jose Barreau, Matthew Recht, Jayapandia Bhaskaran, Ranga Brahmamdam, David Draper, Apurva Mehta, James Maher, Melhem Sharafuddin, Steven Lentz, Andrew Nugent, William Sharp, Timothy Kresowik, Rachel Nicholson, Shiliang Sun, Fadi Youness, Luigi Pascarella, Charles Ray, Martha-Gracia Knuttinen, James Bui, Ron Gaba, Valerie Dobiesz, Ejaz Shamim, Sangeetha Nimmagadda, David Peace, Aarti Zain, Alison Palumto, Ziv Haskal, Jon Mark Hirshon, Howard Richard, Avelino Verceles, Jade Wong-You-Chong, Bertrand Othee, Rahul Patel, Bogdan Iliescu, David Williams, Joseph Gemmete, Wojciech Cwikiel, Kyung Cho, James Schields, Ranjith Vellody, Paula Novelli, Narasimham Dasika, Thomas Wakefield, Jeffrey Desmond, James Froehlich, Minhajuddin Khaja, David Hunter, Jafar Golzarian, Erik Cressman, Yvonne Dotta, Nate Schmiechen, John Marek, David Garcia, Isaac Tawil, Mark Langsfeld, Stephan Moll, Matthew Mauro, Joseph Stavas, Charles Burke, Robert Dixon, Hyeon Yu, Blair Keagy, Kyuny Kim, Raj Kasthuri, Nigel Key, Michael Makaroun, Robert Rhee, Jae−Sung Cho, Donald Baril, Luke Marone, Margaret Hseih, Kristian Feterik, Roy Smith, Geetha Jeyabalan, Jennifer Rogers, Russel Vinik, Dan Kinikini, Larry Kraiss, Michelle Mueller, Robert Pendleton, Matthew Rondina, Mark Sarfati, Nathan Wanner, Stacy Johnson, Christy Hopkins, Daniel Ihnat, John Angle, Alan Matsumoto, Nancy Harthun, Ulku Turba, Wael Saad, Brian Uthlaut, Srikant Nannapaneni, David Ling, Saher Sabri, John Kern, B. Gail Macik, George Hoke, Auh Wahn Park, James Stone, Benjamin Sneed, Scott Syverud, Kelly Davidson, Aditya Sharma, Luke Wilkins, Carl Black, Mark Asay, Daniel Hatch, Robert Smilanich, Craig Patten, S. Douglas Brown, Ryan Nielsen, William Alward, John Collins, Matthew Nokes, Randolph Geary, Matthew Edwards, Christopher Godshall, Pavel Levy, Ronald Winokur, Akhilesh Sista, David Madoff, Kyungmouk Lee, Bradley Pua, Maria DeSancho, Raffaele Milizia, Jing Gao, Gordon McLean, Sanualah Khalid, Larry Lewis, Nael Saad, Mark Thoelke, Robert Pallow, Seth Klein, Gregorio Sicard, Heather L. Gornik, Jim Julian, Stephen Kee, Lawrence Lewis, Elizabeth Magnuson, and Timothy P. Murphy
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Mechanical Thrombolysis ,medicine.medical_treatment ,Catheter directed thrombolysis ,030204 cardiovascular system & hematology ,Iliac Vein ,Article ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Fibrinolytic Agents ,Quality of life ,Randomized controlled trial ,law ,Surveys and Questionnaires ,Internal medicine ,Epidemiology ,Medicine ,Humans ,In patient ,Thrombolytic Therapy ,030212 general & internal medicine ,cardiovascular diseases ,Thrombus ,Venous Thrombosis ,business.industry ,Thrombolysis ,Femoral Vein ,Middle Aged ,medicine.disease ,United States ,humanities ,3. Good health ,Venous thrombosis ,Treatment Outcome ,Quality of Life ,Female ,Surgery ,Cardiology and Cardiovascular Medicine ,business - Abstract
After deep venous thrombosis (DVT), many patients have impaired quality of life (QOL). We aimed to assess whether pharmacomechanical catheter-directed thrombolysis (PCDT) improves short-term or long-term QOL in patients with proximal DVT and whether QOL is related to extent of DVT.The Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (ATTRACT) trial was an assessor-blinded randomized trial that compared PCDT with no PCDT in patients with DVT of the femoral, common femoral, or iliac veins. QOL was assessed at baseline and 1 month, 6 months, 12 months, 18 months, and 24 months using the Venous Insufficiency Epidemiological and Economic Study on Quality of Life/Symptoms (VEINES-QOL/Sym) disease-specific QOL measure and the 36-Item Short Form Health Survey (SF-36) physical component summary (PCS) and mental component summary general QOL measures. Change in QOL scores from baseline to assessment time were compared in the PCDT and no PCDT treatment groups overall and in the iliofemoral DVT and femoral-popliteal DVT subgroups.Of 692 ATTRACT patients, 691 were analyzed (mean age, 53 years; 62% male; 57% iliofemoral DVT). VEINES-QOL change scores were greater (ie, better) in PCDT vs no PCDT from baseline to 1 month (difference, 5.7; P = .0006) and from baseline to 6 months (5.1; P = .0029) but not for other intervals. SF-36 PCS change scores were greater in PCDT vs no PCDT from baseline to 1 month (difference, 2.4; P = .01) but not for other intervals. Among iliofemoral DVT patients, VEINES-QOL change scores from baseline to all assessments were greater in the PCDT vs no PCDT group; this was statistically significant in the intention-to-treat analysis at 1 month (difference, 10.0; P .0001) and 6 months (8.8; P .0001) and in the per-protocol analysis at 18 months (difference, 5.8; P = .0086) and 24 months (difference, 6.6; P = .0067). SF-36 PCS change scores were greater in PCDT vs no PCDT from baseline to 1 month (difference, 3.2; P = .0010) but not for other intervals. In contrast, in femoral-popliteal DVT patients, change scores from baseline to all assessments were similar in the PCDT and no PCDT groups.Among patients with proximal DVT, PCDT leads to greater improvement in disease-specific QOL than no PCDT at 1 month and 6 months but not later. In patients with iliofemoral DVT, PCDT led to greater improvement in disease-specific QOL during 24 months.
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- 2020
117. Safety Factor for Drilled Shaft Foundations Subjected to Wind-Induced Torsion
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Aguilar, Victor, Nowak, Andrzej, J Michael Stallings, and J Brian Anderson
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- 2020
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118. Climate reconstructions for the Last Glacial Maximum from a simple cirque glacier in Fiordland, New Zealand
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Emily M.M. Moore, Alan J. Hidy, Shaun R. Eaves, Kevin Norton, Lisa H. Dowling, Brian Anderson, and Andrew Mackintosh
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Marine isotope stage ,Archeology ,Global and Planetary Change ,geography ,geography.geographical_feature_category ,Geology ,Glacier ,Last Glacial Maximum ,Cirque glacier ,Glacier morphology ,Moraine ,Deglaciation ,Physical geography ,Glacial period ,Ecology, Evolution, Behavior and Systematics - Abstract
Mountain glacier records offer important constraints on the timing and magnitude of climate variability during the last glacial cycle. Existing moraine chronologies from the central Southern Alps indicate maximum ice extent was achieved during marine isotope stages 3–4, followed by repeated advances of similar, but gradually declining extent during marine isotope stage 2, until onset of the glacial termination. Questions remain over the precise role of climate in driving these changes, as most existing moraine chronologies come from large, complex former valley glacier systems, where non-climatic influences such as changing bed topography and proglacial lake formation may have influenced glacier length changes. Here we address this problem via a new cosmogenic 10Be chronology and equilibrium line altitude reconstruction from a cirque glacier situated in Fiordland, New Zealand. Our chronology shows moraine deposition at 32 ± 11 ka, 18.7 ± 0.2 ka, 18.1 ± 0.1 ka, and c. 17.2 ± 0.3 ka. The simple geometry of the former glacier supports the role of climate in driving a net decline of regional ice volume during marine isotope stages 3–2. Close spacing and good preservation of the 19–17 ka moraines permits 2D glacier reconstruction which suggests the equilibrium line altitude remained depressed by c.1130 m (equivalent to 5.8 ± 0.6 °C colder than present) during this interval. Onset of warming after 17.2 ± 0.2 ka is consistent with climate proxy evidence for a sustained southward shift in the southern westerly winds, which may have promoted deglaciation via shifting ocean currents and promoting increases in atmospheric carbon dioxide.
- Published
- 2022
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119. Scientific Abstracts and Sessions
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Gian Luca Poli, Alexander F. I. Osman, Hesheng Wang, Chuan Zeng, Jiangyang Zhang, Peter Schiff, Florent Tixier, Douglas Kondziolka, Lawrence Dauer, Jinyu Xue, Christian Valdes, Ting Chen, Gikas Mageras, Aditi Iyer, Joshua Silverman, and Brian Anderson
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03 medical and health sciences ,Mathematical optimization ,0302 clinical medicine ,Computer science ,030220 oncology & carcinogenesis ,Dose prediction ,Pareto principle ,General Medicine ,030218 nuclear medicine & medical imaging - Published
- 2018
- Full Text
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120. 10 minutes with Dr. Brian Anderson, Chief Digital Health Physician at the MITRE Corporation, Massachusetts, USA
- Author
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Tuna Cem Hayirli and Brian Anderson
- Subjects
Government ,Leadership and Management ,business.industry ,Strategy and Management ,Health Policy ,Social anthropology ,Information technology ,Biography ,Corporation ,Digital health ,Management ,General partnership ,Political science ,Health care ,business - Abstract
Biography Dr. Brian Anderson is the Chief Digital Health Physician at the MITRE Corporation. After completing his undergraduate degree in Social Anthropology at Harvard College, he received his medical doctorate from Harvard Medical School and continued his medical training at Massachusetts General Hospital. He has served on several national health information technology committees in partnership with the Office of the National Coordinator, and previously was an Informatics Department Head at athenahealth. He is passionate about working at the intersection of technology, evidence-based medicine, predictive analytics. ![Graphic][1] During the pandemic, Dr. Anderson has served as the Strategic Manager of the COVID-19 Healthcare Coalition, as well as an Executive Steering Committee Member for The Fight Is In Us coalition. The COVID-19 Healthcare Coalition is a private-sector led response to the pandemic, co-chaired by MITRE and the Mayo Clinic, driven to preserve the US healthcare delivery system during the pandemic by bringing together over a thousand healthcare organisations, technology firms, non-profits, academia and startups. The Fight Is In Us coalition similarly represents a united effort against COVID-19, bringing together business, non-profit, government and community leaders who are motivated to raise awareness for and facilitate the fair and equitable distribution of convalescent plasma. The key message is that what we can do when we collaborate in non-traditional, public–private–community partnerships can be profound. Barney Frank, a former congressman from Massachusetts, once said that ‘government is simply the name we give to the things we choose to do together’. A public–private–community partnership in some ways blurs the line between what exactly is government and what is people just coming together to do the right thing. Having stakeholders from all three of those categories is the purest sense and truest expression of collaboration. In this pandemic, I have seen what we can do when those groups come together and … [1]: /embed/inline-graphic-1.gif
- Published
- 2021
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121. The Conjurers #3: Fight of the Fallen
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Brian Anderson and Brian Anderson
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- Fiction, Fantasy fiction, Juvenile works, Action and adventure fiction, Children's stories, Magicians--Fiction, Magic--Fiction, Families--Fiction, Fantasy
- Abstract
In the epic conclusion to the Conjurian series, siblings Alex and Emma must fight to save the enchanted world, where magic is real and skilled illusionists can perform actual tricks—for better or worse. This fantasy series is perfect for fans of The Land of Stories series.“A magical adventure inspired by us? We have to read it! And so do you!” —Penn Jillette, half of the Emmy-winning magic-comedy duo Penn & Teller Years ago, Alex and Emma's parents disappeared trying to protect magic. Now Alex thinks he knows how to find them—if only his sister, their talking rabbit Pimawa, and their friend Savachia would trust fate to guide the way. The problem: Alex's “fate” keeps leading the group straight into danger. Specifically, into an enchanted jungle where a tree-like creature named Awen seems intent on doing them harm. But Alex is certain Awen knows more than she is letting on. And when she is captured, the kids follow the trail to the city of magic: Las Vegas. In the desert, sleight-of-hand runs the show, and at the center of it all is Angel Xavier, an evil conjurian who will stop at nothing to seize power. The kids need a trick up their sleeve—and a few new allies to help—if they have any hope of saving their parents, and magic, once and for all!
- Published
- 2022
122. Modelled response of debris-covered and lake-calving glaciers to climate change, Kā Tiritiri o te Moana/Southern Alps, New Zealand
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A. Sood, Johannes Oerlemans, Alice M. Doughty, B. Mullan, C. Zammit, Andrew Mackintosh, Ruzica Dadic, and Brian Anderson
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Global and Planetary Change ,geography ,geography.geographical_feature_category ,Atmospheric circulation ,Ice calving ,Climate change ,Glacier ,Present day ,Oceanography ,Debris ,Greenhouse gas ,Environmental science ,Physical geography ,Climate state - Abstract
Glaciers will lose mass during the next decades as the climate warms. While the largest uncertainty in this mass loss is the global greenhouse gas emissions pathway, on a local or regional scale there are large uncertainties in some processes that influence glacier response. We explore the competing processes of reduced ablation under debris cover and increased ablation from calving by applying a coupled mass-balance/ice-flow model in the central Southern Alps/Kā Tiritiri o te Moana of New Zealand. Glacier volume loss is assessed over the period from AD 1880 to AD 2099, driven by observed climate data before 2005, and perturbing the modern climate state and imposing representative concentration pathway (RCP) scenarios 2.6–8.5 as expressed by six global circulation models (GCMs) which leads to a regional warming of between 1–4 °C (2006–2099). Key findings are (1) modelled ice volume reduced from 47 km3 to 29 km3 between AD 1880 and 2005; (2) over the period 2006–2099 further volume loss to 24 km3 (19% reduction) is committed under present-day climate; (3) modelled ice volume at AD 2099 is estimated at 2 km3 ± 6 km3 (RCP8.5) to 15 km3 ± 6 km3 (RCP2.6), a reduction of 50–92% relative to present day. The wide range of projected ice volumes reflects the large range of temperature projections between RCP2.6 and RCP8.5. The mode and timing of ice loss provides insight into processes that will drive future glacier behavior. Under RCP2.6 at 2099, the glaciers retain a similar configuration to present, although clean-ice glaciers will retreat significantly, and some debris-covered tongues will disconnect from their accumulation areas. For RCP4.5, RCP6.0 and RCP8.5 the clean-ice glaciers will retreat to become small remnants in the high mountains. Experiments where the debris cover is removed shows a much faster loss of ice, whereas experiments with no lake calving slows ice loss. However, under all but the most moderate warming scenarios, by 2099 the strong climatic forcing overwhelms these processes as there is little ice left at low elevations where debris cover and lake calving occur.
- Published
- 2021
- Full Text
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123. The Conjurers #2: Hunt for the Lost
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Brian Anderson and Brian Anderson
- Subjects
- Magic--Fiction, Siblings--Fiction, Rabbits--Fiction, Fantasy
- Abstract
Siblings Emma and Alex fall deeper into the magical world of the Conjurian--a place where illusionists called conjurers can perform actual tricks--in book two of this new highly-illustrated fantasy adventure series that's perfect for fans of the Land of Stories.The hunt is on for the Eye of Dedi--the legendary object that stores magic untold--and siblings Alex and Emma are determined to get it first. The only problem? They're not the only ones looking. Hot on their heels is the evil Shadow Conjurer who will stop at nothing to get his hands on the Eye and finally control all of the Conjurian world. It's up to Alex and Emma to outsmart the Shadow Conjurer and his league of ghastly monsters, or risk losing magic forever.Fall under the spell of the Conjurers. Masterful storytelling and over 100 captivating black-and-white illustrations fill the world of this story with charm and intrigue.
- Published
- 2021
124. Local summer insolation and greenhouse gas forcing drove warming and glacier retreat in New Zealand during the Holocene
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Alan J. Hidy, Brian Anderson, Matthew T. Ryan, Shaun R. Eaves, Andrew Mackintosh, Lauren Vargo, Lisa Dowling, Andrew Lorrey, Stephen G. Tims, and Kevin Norton
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Archeology ,Global and Planetary Change ,geography ,geography.geographical_feature_category ,Geology ,Glacier ,Last Glacial Maximum ,Seasonality ,medicine.disease ,Moraine ,Greenhouse gas ,Interglacial ,Temperate climate ,medicine ,Physical geography ,Ecology, Evolution, Behavior and Systematics ,Holocene ,Uncategorized - Abstract
Geological climate archives from the Holocene Epoch provide baseline information concerning natural climate variability. Temperate mountain glacier extent is sensitive to summer air temperature, thus geological records of past glacier length changes are a useful proxy for this climatic variable. Here we present a new cosmogenic 10Be chronology of glacier length changes at Dart Glacier in the Southern Alps, New Zealand. Prominent moraines deposited 321 ± 44 yr ago (n = 11) and 7.8 ± 0.3 ka (n = 5) show glaciers during the Little Ice Age were less extensive than during the early Holocene. This pattern of net Holocene glacier retreat is consistent with emerging data from other catchments in New Zealand and across the southern mid-latitudes. Using the physical framework of a transient global climate model simulation, we suggest that cool summers in the early Holocene were promoted by the local summer insolation minimum, together with low atmospheric greenhouse gas concentrations, causing an early Holocene austral glacial maximum. An insolation-driven reduction in seasonality at southern mid-latitudes may reconcile differences between early Holocene temperature reconstructions where climate proxies have different seasonal sensitivities. We suggest that rising greenhouse gas concentrations after 7 ka caused regional-scale glacier retreat and appear to be the dominant driver of multi-millennial summer temperature trends in the southern mid-latitudes during the present interglacial.
- Published
- 2021
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125. Using structure from motion photogrammetry to measure past glacier changes from historic aerial photographs
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Lauren Vargo, Andrew Mackintosh, Huw J. Horgan, Andrew Lorrey, Brian Anderson, and Merijn Thornton
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geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Glacier ,010502 geochemistry & geophysics ,01 natural sciences ,Photogrammetry ,Structure from motion ,Cryosphere ,Lower cost ,Physical geography ,Geology ,0105 earth and related environmental sciences ,Earth-Surface Processes ,Equilibrium line - Abstract
Quantifying historic changes in glacier size and mass balance is important for understanding how the cryosphere responds to climate variability and change. Airborne photogrammetry enables glacier extent and equilibrium line altitudes (ELAs) to be monitored for more glaciers at lower cost than traditional mass-balance programs and other remote-sensing techniques. Since 1977, end-of-summer-snowlines, which are a proxy for annual ELAs, have been recorded for 50 glaciers in the Southern Alps of New Zealand using oblique aerial photographs. In this study, we use structure from motion photogrammetry to estimate the camera parameters, including position, for historic photographs, which we then use to measure glacier change. We apply this method to a small maritime New Zealand glacier (Brewster Glacier, 1670–2400 m a.s.l.) to derive annual ELA and length records between 1981 and 2017, and quantify the uncertainties associated with the method. Our length reconstruction shows largely continuous terminus retreat of 365 ± 12 m for Brewster Glacier since 1981. The ELA record, which compares well with glaciological mass-balance data measured between 2005 and 2015, shows pronounced interannual variability. Mean ELAs range from 1707 ± 6 to 2303 ± 5 m a.s.l., with the highest ELAs occurring in the last decade.
- Published
- 2017
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126. Reconstructing Climate from Glaciers
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Brian Anderson, Raymond T. Pierrehumbert, and Andrew Mackintosh
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geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Climate oscillation ,Global warming ,Astronomy and Astrophysics ,Glacier ,Last Glacial Maximum ,010502 geochemistry & geophysics ,01 natural sciences ,Glacier mass balance ,Space and Planetary Science ,Climatology ,Paleoclimatology ,Earth and Planetary Sciences (miscellaneous) ,Glacial period ,Climate state ,Geology ,0105 earth and related environmental sciences - Abstract
Glaciers offer the potential to reconstruct past climate over timescales from decades to millennia. They are found on nearly every continent, and at the Last Glacial Maximum, glaciers were larger in all regions on Earth. The physics of glacier-climate interaction are relatively well understood, and glacier models can be used to reconstruct past climate from geological evidence of past glacier extent. This can lead to significant insights regarding past, present, and future climate. For example, glacier modeling has demonstrated that the near-ubiquitous global pattern of glacier retreat during the last few centuries resulted from a global-scale climate warming of ∼1°C, consistent with instrumental data and climate proxy records. Climate reconstructions from glaciers have also demonstrated that the tropics were colder at the Last Glacial Maximum than was originally inferred from sea surface temperature reconstructions. Future efforts to reconstruct climate from glaciers may provide new constraints on climate sensitivity to CO2 forcing, polar amplification of climate change, and more.
- Published
- 2017
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127. An exercise in glacier length modeling: Interannual climatic variability alone cannot explain Holocene glacier fluctuations in New Zealand
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Andrew Mackintosh, David J.A. Barrell, Aaron E. Putnam, Brian Anderson, Joerg M. Schaefer, Trevor Chinn, Ruzica Dadic, Alice M. Doughty, and George H. Denton
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geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Magnitude (mathematics) ,Glacier ,Radiative forcing ,010502 geochemistry & geophysics ,01 natural sciences ,Glacier mass balance ,Geophysics ,Space and Planetary Science ,Geochemistry and Petrology ,Moraine ,Climatology ,Paleoclimatology ,Earth and Planetary Sciences (miscellaneous) ,Precipitation ,Geology ,Holocene ,0105 earth and related environmental sciences - Abstract
Recent model studies suggest that interannual climatic variability could be confounding the interpretation of glacier fluctuations as climate signals. Paleoclimate interpretations of moraine positions and associated cosmogenic exposure ages may have large uncertainties if the glacier in question was sensitive to interannual variability. Here we address the potential for interannual temperature and precipitation variability to cause large shifts in glacier length during the Holocene. Using a coupled ice-flow and mass-balance model, we simulate the response of Cameron Glacier, a small mountain glacier in New Zealand's Southern Alps, to two types of climate forcing: equilibrium climate and variable climate. Our equilibrium results suggest a net warming trend from the Early Holocene ( 10.69 ± 0.41 ka; 2.7 °C cooler than present) to the Late Holocene (CE 1864; 1.3 °C cooler than present). Interannual climatic variability cannot account for the Holocene glacier fluctuations in this valley. Future studies should consider local environmental characteristics, such as a glacier's climatic setting and topography, to determine the magnitude of glacier length changes caused by interannual variability.
- Published
- 2017
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128. Regional cooling caused recent New Zealand glacier advances in a period of global warming
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Andrew Mackintosh, Brian Anderson, S. M. Dean, Andrew Lorrey, Prisco Frei, and James A. Renwick
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geography ,Multidisciplinary ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Atmospheric circulation ,Science ,Global warming ,General Physics and Astronomy ,Glacier ,General Chemistry ,010502 geochemistry & geophysics ,01 natural sciences ,General Biochemistry, Genetics and Molecular Biology ,Article ,Sea surface temperature ,Glacier mass balance ,Oceanography ,Moraine ,Extratropical cyclone ,Precipitation ,Physical geography ,Geology ,0105 earth and related environmental sciences - Abstract
Glaciers experienced worldwide retreat during the twentieth and early twenty first centuries, and the negative trend in global glacier mass balance since the early 1990s is predominantly a response to anthropogenic climate warming. The exceptional terminus advance of some glaciers during recent global warming is thought to relate to locally specific climate conditions, such as increased precipitation. In New Zealand, at least 58 glaciers advanced between 1983 and 2008, and Franz Josef and Fox glaciers advanced nearly continuously during this time. Here we show that the glacier advance phase resulted predominantly from discrete periods of reduced air temperature, rather than increased precipitation. The lower temperatures were associated with anomalous southerly winds and low sea surface temperature in the Tasman Sea region. These conditions result from variability in the structure of the extratropical atmospheric circulation over the South Pacific. While this sequence of climate variability and its effect on New Zealand glaciers is unusual on a global scale, it remains consistent with a climate system that is being modified by humans., Many New Zealand glaciers advanced during recent global warming, bucking a worldwide trend of glacier retreat. Here, the authors show that these glacier advances were forced by a sequence of unusually cool years in the New Zealand region, rather than a period of increased precipitation.
- Published
- 2017
129. Rejoinder
- Author
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Monica M Bertagnolli, Brian Anderson, Andre Quina, and Steven Piantadosi
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Pharmacology ,General Medicine - Published
- 2020
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130. Big Can Be Beautiful!
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Brian Anderson and Luis I. Cortinez
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business.industry ,Medicine ,business - Published
- 2019
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131. Covariate Analysis in Clinical Anaesthesia
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Brian Anderson and Luis I. Cortinez
- Subjects
Covariate analysis ,business.industry ,Anesthesia ,Medicine ,business - Published
- 2019
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132. Beam combinable, kilowatt all-fiber amplifiers for directed energy
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Nader A. Naderi, Iyad Dajani, Angel Flores, and Brian Anderson
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Physics ,Wavelength ,Brightness ,Optics ,business.industry ,Fiber laser ,Amplifier ,Physics::Accelerator Physics ,Near and far field ,business ,Polarization (waves) ,Beam (structure) ,Coherence (physics) - Abstract
In this chapter, several beam combining architectures suitable for DE applications have been reported, and are divided into two distinct categories: incoherent beam combination (IBC) and coherent beam combination (CBC). The purpose of each method is to increase the far field intensity when brightness and power of a single fiber amplifier is limited. In IBC, an array of fiber lasers is superimposed in the far field without control of the relative spectra or phases of the different fibers. No brightness enhancement is obtained from this method, limiting the maximum intensity in the far field. Although such beam combining has been successfully demonstrated by the Navy [5], this approach is limited to propagation ranges on the order of a few kilometers. In spectral beam combining (SBC), a separate class of IBC, incoherent beams of different wavelengths are spatially overlapped to create a single output beam of multiple colors. The brightness of the propagating beam can be increased at the cost of increased spectral bandwidth. Similarly, SBC has the advantage of not requiring active phase control or mutual temporal coherence of the individual beams. Alternatively, coherent beam combining (CBC) schemes require proper phase, frequency, and polarization relationships for efficient beam combination. Overall, due to their brightness enhancements, for longer range and higher power/ intensity DE applications, SBC and CBC are potentially more appealing.
- Published
- 2019
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133. High Power All-Fiber Amplifiers at Air Force Research Laboratory (AFRL)
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Roger Holten, Ken Rowland, Iyad Dajani, Brian Anderson, Thomas Ehrenreich, Angel Flores, and Nader A. Naderi
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Nonlinear system ,Optics ,Materials science ,business.industry ,Fiber laser ,Amplifier ,Gain ,Nonlinear optics ,business ,Phase modulation ,Beam (structure) ,Power (physics) - Abstract
We present an overview of fiber amplifier power-scaling and beam-combining at AFRL. Nonlinear mitigation and power-scaling results of kW amplifiers is discussed. Here nonlinear suppression is attained through phase modulation and laser gain competition. Subsequently, five kW amplifiers were coherently combined into one 5kW beam.
- Published
- 2019
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134. Multimodal imaging of bacterial-host interface in mice and piglets with
- Author
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Peter, Panizzi, Marvin, Krohn-Grimberghe, Edmund, Keliher, Yu-Xiang, Ye, Jana, Grune, Vanessa, Frodermann, Yuan, Sun, Charlotte G, Muse, Kaitlyn, Bushey, Yoshiko, Iwamoto, Mandy M T, van Leent, Anu, Meerwaldt, Yohana C, Toner, Jazz, Munitz, Alexander, Maier, Georgios, Soultanidis, Claudia, Calcagno, Carlos, Pérez-Medina, Giuseppe, Carlucci, Kay P, Riddell, Sharron, Barney, Glenn, Horne, Brian, Anderson, Ashoka, Maddur-Appajaiah, Ingrid M, Verhamme, Paul E, Bock, Gregory R, Wojtkiewicz, Gabriel, Courties, Filip K, Swirski, William R, Church, Paul H, Walz, D Michael, Tillson, Willem J M, Mulder, and Matthias, Nahrendorf
- Subjects
Coagulase ,Mice ,Staphylococcus aureus ,Swine ,Animals ,Endocarditis, Bacterial ,Staphylococcal Infections ,Multimodal Imaging ,Article - Abstract
Acute bacterial endocarditis is a rapid, difficult to manage and frequently lethal disease. Potent antibiotics often cannot efficiently kill Staphylococcus aureus (S. aureus) that colonizes the heart’s valves. S. aureus relies on virulence factors to evade therapeutics and the host’s immune response, usurping the host’s clotting system by activating circulating prothrombin with staphylocoagulase and von Willebrand factor-binding protein. An insoluble fibrin barrier then forms around the bacterial colony, shielding the pathogen from immune cell clearance. Targeting virulence factors may provide previously unidentified avenues to better diagnose and treat endocarditis. To tap into this unused therapeutic opportunity, we co-developed therapeutics and multimodal molecular imaging to probe the host-pathogen interface. We introduced and validated a family of small-molecule optical and positron emission tomography (PET) reporters targeting active thrombin in the fibrin-rich environment of bacterial colonies. The imaging agents, based on the clinical thrombin inhibitor dabigatran, bound to heart valve vegetations in mice. Using optical imaging, we monitored therapy with antibodies neutralizing staphylocoagulase and von Willebrand factor binding protein in mice with S. aureus endocarditis. This treatment deactivated bacterial defenses against innate immune cells, decreased in vivo imaging signal and improved survival. Aortic or tricuspid S. aureus endocarditis in piglets was also successfully imaged with clinical PET/magnetic resonance imaging (MRI). Our data map a route towards adjuvant immunotherapy for endocarditis and provide efficient tools to monitor this drug class for infectious diseases.
- Published
- 2019
135. The ERG1a K + Channel Increases Intracellular Calcium and Calpain Activity in C2C12 Myotubes
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Rod Weilbaecher, Amy E. Salyer, Judy K. Davie, Gregory H. Hockerman, Evan E. Pratt, Clayton L. Whitmore, Sandra Zampieri, Luke Brian Anderson, Amber Lynn Pond, Emily K. Rantz, and Ugo Carraro
- Subjects
Chemistry ,Myogenesis ,Genetics ,Molecular Biology ,Biochemistry ,C2C12 ,Calcium in biology ,Calpain activity ,Biotechnology ,K channels ,Cell biology - Published
- 2019
- Full Text
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136. MON-481 MA-[D-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Enhances the Effects of Insulin on Glycemic Control and Cognitive Function in Streptozotocin-Induced Hyperglycemic Swiss Webster Mice
- Author
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Brian Anderson, Guirong Wang, Zachary Novakovic, and Patricia Grasso
- Subjects
chemistry.chemical_classification ,SWISS WEBSTER ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Leptin ,Insulin ,medicine.medical_treatment ,Peptide ,Streptozotocin ,Small molecule ,Endocrinology ,Neuroendocrinology and Pituitary ,chemistry ,Internal medicine ,medicine ,Pituitary Tumors and GHRH, GH, and IGF Biology and Signaling ,Glycemic ,medicine.drug - Abstract
Glucose dysregulation and disruption of insulin signaling in the brain have been suggested as a possible etiology of Alzheimer’s Disease. In the present study, we show that oral delivery of MA-[D-Leu-4]-OB3 to young male Swiss Webster (SW) mice rendered hyperglycemic by intraperitoneal injection of streptozotocin (STZ), prevented insulin-induced increase in body weight gain and enhanced the effects of insulin alone on fasting blood glucose to levels approaching those of normal SW mice of the same age and sex. Novel object testing indicated that insulin treatment improved working memory in STZ-induced hyperglycemic mice, and that MA-[D-Leu-4]-OB3 given in combination with insulin significantly accelerated the time course of this improvement. Although positive results in an animal model may not be recapitulated in human pathology, our data suggest that MA-[D-Leu-4]-OB3, when added to an insulin regimen, may have application to the treatment of Alzheimer’s Disease by improving insulin sensitivity and glycemic control, thus slowing or preventing the progression of memory disruption associated with this disease.
- Published
- 2019
137. Construction and Monitoring of Alabama’s First Geosynthetic Reinforced Soil-Integrated Bridge System
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J. Brian Anderson, R. Jonathan Hogan, Robert Pirando, and Jack Montgomery
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Engineering ,business.industry ,Forensic engineering ,business ,Bridge (interpersonal) - Published
- 2019
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138. Framework for quantifying flow and sediment yield to diagnose and solve the aggradation problem of an ungauged catchment
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Xing Fang, Jose G. Vasconcelos, Sagar K. Tamang, J. Brian Anderson, and Wenjun Song
- Subjects
lcsh:GE1-350 ,Hydrology ,geography ,geography.geographical_feature_category ,lcsh:QE1-996.5 ,Drainage basin ,Sediment ,General Medicine ,Land cover ,lcsh:Geology ,Universal Soil Loss Equation ,Aggradation ,Deforestation ,Streamflow ,Erosion ,Environmental science ,lcsh:Environmental sciences - Abstract
Estimating sediment deposition in a stream, a standard procedure for dealing with aggradation problem is complicated in an ungauged catchment due to the absence of necessary flow data. A serious aggradation problem within an ungauged catchment in Alabama, USA, blocked the conveyance of a bridge, reducing the clearance under the bridge from several feet to a couple of inches. A study of historical aerial imageries showed deforestation in the catchment by a significant amount over a period consistent with the first identification of the problem. To further diagnose the aggradation problem, due to the lack of any gauging stations, local rainfall, flow, and sediment measurements were attempted. However, due to the difficulty of installing an area-velocity sensor in an actively aggrading stream, the parameter transfer process for a hydrologic model was adopted to understand/estimate streamflow. Simulated discharge combined with erosion parameters of MUSLE (modified universal soil loss equation) helped in the estimation of sediment yield of the catchment. Sediment yield for the catchment showed a significant increase in recent years. A two-dimensional hydraulic model was developed at the bridge site to examine potential engineering strategies to wash sediments off and mitigate further aggradation. This study is to quantify the increase of sediment yield in an ungauged catchment due to land cover changes and other contributing factors and develop strategies and recommendations for preventing future aggradation in the vicinity of the bridge.
- Published
- 2019
139. Bioinspired sensing and control for underwater pursuit
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Free, Brian Anderson
- Subjects
Aerospace engineering ,estimation ,bioinspired ,Robotics ,dynamics ,nonlinear control ,pursuit - Abstract
Fish in nature have several distinct advantages over traditional propeller driven underwater vehicles including maneuverability and flow sensing capabilities. Taking inspiration from biology, this work seeks to answer three questions related to bioinspired pursuit and apply the knowledge gained therein to the control of a novel, reaction-wheel driven autonomous fish robot. Which factors are most important to a successful pursuit? How might we guarantee capture with underwater pursuit? How might we track the wake of a flapping fish or vehicle? A technique called probabilistic analytical modeling (PAM) is developed and illustrated by the interactions between predator and prey fish in two case studies that draw on recent experiments. The technique provides a method for investigators to analyze kinematics time series of pursuit to determine which parameters (e.g. speed, flush distance, and escape angles) have the greatest impact on metrics such as probability of survival. Providing theoretical guarantees of capture become complicated in the case of a swimming fish or bioinspired fish robot because of the oscillatory nature fish motion. A feedback control law is shown to result in forward swimming motion in a desired direction. Analysis of this law in a pursuit scenario yields a condition stating whether capture is guaranteed provided some basic information about the motion of the prey. To address wake tracking inspiration is taken from the lateral line sensing organ in fish, which is sensitive to hydrodynamic forces in the local flow field. In experiment, an array of pressure sensors on a Joukowski foil estimates and controls flow-relative position in a Karman vortex street using potential flow theory, recursive Bayesian filtering, and trajectory-tracking, feedback control. The work in this dissertation pushes the state of the art in bioinspired underwater vehicles closer to what can be found in nature. A modeling technique provides a means to determine what is most important to pursuit when designing a vehicle, analysis of a control law shows that a robotic fish is capable of pursuit engagements with capture guarantees, and an estimation framework demonstrates how the wake of a swimming fish or obstacle in the flow can be tracked.
- Published
- 2019
- Full Text
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140. Contributors
- Author
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Beatriz A. Acosta-Estrada, Helbert Almeida, Brian Anderson, Silvina Arias, Ana Paula Badan-Ribeiro, Daniel Barrera-Arellano, James N. BeMiller, Carl J. Bern, José Luis Cabrera-Ponce, Cristina Chuck-Hernandez, L.L. Darrah, Francisco Javier Belden Fernandez, Silverio García-Lara, Christiane Gruber-Dorninger, Janet A. Gutiérrez-Uribe, Bruce R. Hamaker, Scott Helstad, Floyd L. Herum, Nicholas Hoffman, Dell Hummel, Lawrence A. Johnson, Deepak Kumar, Brian A. Larkins, D.D. Loy, E.L. Lundy, Ernesto Lozano Martinez, Linda J. Mason, James B. May, M.D. McMullen, Randall Montgomery, Gary P. Munkvold, Marvin R. Paulsen, Esther Perez Carrillo, Richard C. Pratt, Graeme Quick, Kent D. Rausch, Paul Scott, Sergio O. Serna-Saldivar, Xinyu Shen, Mukti Singh, Vijay Singh, Ines Taschl, Diana Lilia Trejo-Saavedra, Yunus E. Tuncil, Eliana Valencia-Lozano, Tong Wang, Pamela J. White, and M.S. Zuber
- Published
- 2019
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141. FACTORS ASSOCIATED WITH 30-DAY AMPUTATION IN PATIENTS WITH CRITICAL LIMB ISCHEMIA UNDERGOING ENDOVASCULAR INTERVENTION
- Author
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Kim G. Smolderen, Mark A. Hoffman, Matthew C. Bunte, Philip Jones, Carlos Mena Hurtado, Brian Anderson, Jeremy Provance, John A. Spertus, and Todd R. Vogel
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medicine.medical_specialty ,Amputation ,business.industry ,medicine.medical_treatment ,Intervention (counseling) ,Medicine ,In patient ,Critical limb ischemia ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Surgery - Published
- 2021
- Full Text
- View/download PDF
142. The Conjurers #1: Rise of the Shadow
- Author
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Brian Anderson and Brian Anderson
- Subjects
- Children's stories, Action and adventure fiction, Fantasy fiction, Fiction, Juvenile works, Magicians--Juvenile fiction, Magic--Juvenile fiction, Families--Juvenile fiction
- Abstract
Siblings Emma and Alex tumble into a secret world where magic is real and skilled illusionists can perform actual tricks--for better or worse. Perfect for fans of the Magic Misfits and the Land of Stories series.After their parents vanished, Alex and Emma are sent to live with strict Uncle Mordo. Only Emma's pet rabbit, Pimawa, keeps them company. But when flying skeletons called Rag-o-Rocs storm their once-quiet home, the kids escape just in time with Pimawa leading the way.The rabbit takes the siblings to the Conjurian, a land where magic exists and Pimawa can talk. But the Conjurian is in trouble. Magic has been disappearing, and the Shadow Conjurer, the most mysterious sorcerer of all, is on the hunt for the Eye of Dedi, an object so powerful it could destroy the Conjurian and human worlds. The battle to control all magic has begun. There's only one problem: Alex and Emma don't have any!Masterful storytelling and dozens of captivating illustrations fill author-illustrator Brian Anderson's world with charm and intrigue. Fall under the spell of the Conjurers.
- Published
- 2020
143. UCSF End-of-Life Option Act 2016–2019: A Retrospective Chart Review Pilot (SCI923)
- Author
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Jordie Martin, Brian Anderson, Eric Weaver, and Lawrence Kaplan
- Subjects
Anesthesiology and Pain Medicine ,business.industry ,Chart review ,Medicine ,Neurology (clinical) ,Medical emergency ,business ,medicine.disease ,General Nursing - Published
- 2021
- Full Text
- View/download PDF
144. An 11-year record of mass balance of Brewster Glacier, New Zealand, determined using a geostatistical approach
- Author
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Andrew Mackintosh, Huw J. Horgan, Brian Anderson, Nicolas J. Cullen, J. P. Conway, Sean J. Fitzsimons, Pascal Sirguey, Andrew Lorrey, D. Stumm, and Ruzica Dadic
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Hydrology ,geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Elevation ,Sampling (statistics) ,Glacier ,Geostatistics ,010502 geochemistry & geophysics ,Snow ,01 natural sciences ,Spatial variability ,Physical geography ,Digital elevation model ,Southern Hemisphere ,Geology ,0105 earth and related environmental sciences ,Earth-Surface Processes - Abstract
Recognising the scarcity of glacier mass-balance data in the Southern Hemisphere, a mass-balance measurement programme was started at Brewster Glacier in the Southern Alps of New Zealand in 2004. Evolution of the measurement regime over the 11 years of data recorded means there are differences in the spatial density of data obtained. To ensure the temporal integrity of the dataset a new geostatistical approach is developed to calculate mass balance. Spatial co-variance between elevation and snow depth allows a digital elevation model to be used in a co-kriging approach to develop a snow depth index (SDI). By capturing the observed spatial variability in snow depth, the SDI is a more reliable predictor than elevation and is used to adjust each year of measurements consistently despite variability in sampling spatial density. The SDI also resolves the spatial structure of summer balance better than elevation. Co-kriging is used again to spatially interpolate a derived mean summer balance index using SDI as a co-variate, which yields a spatial predictor for summer balance. The average glacier-wide surface winter, summer and annual balances over the period 2005–15 are 2484, −2586 and −102 mm w.e., respectively, with changes in summer balance explaining most of the variability in annual balance.
- Published
- 2016
- Full Text
- View/download PDF
145. Glacier-based climate reconstructions for the last glacial-interglacial transition: Arthur's Pass, New Zealand (43°S)
- Author
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Andrew Mackintosh, Shaun R. Eaves, and Brian Anderson
- Subjects
geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Tidewater glacier cycle ,Paleontology ,Glacier ,Cirque glacier ,010502 geochemistry & geophysics ,01 natural sciences ,Glacier mass balance ,Arts and Humanities (miscellaneous) ,Moraine ,Climatology ,Interglacial ,Earth and Planetary Sciences (miscellaneous) ,Snow line ,Glacial period ,Physical geography ,Geology ,0105 earth and related environmental sciences - Abstract
Geological records of mountain glacier fluctuations provide useful evidence for tracing the magnitude and rate of past temperature change. In this study, we present air temperature reconstructions for the last glacial termination in New Zealand derived using snowline reconstructions and numerical glacier modelling. We target the Arthur's Pass moraines in the Otira River catchment, which have previously been dated to the Lateglacial using cosmogenic 10Be. Recalculation of these exposure ages using a locally calibrated 10Be production rate indicates that these moraines formed ca. 16–14 ka. Our glacier modelling experiments and snowline reconstructions exhibit good agreement and show that the Arthur's Pass moraines formed in a climate that was 2.2–3.5 °C colder than present. Combining our results with other, proximal glacier records shows that ice in this catchment retreated ca. 50 km from the coastal plain to the main divide during the interval 17–15 ka, in response to a temperature increase of at least ca. 3 °C. Over half of this retreat occurred after the glacier had withdrawn from an overdeepened basin. Thus, we conclude that temperature increase was the primary driver of widespread and rapid glacier retreat in New Zealand at the onset of the last glacial termination.
- Published
- 2016
- Full Text
- View/download PDF
146. Exploring the source-to-sink residence time of terrestrial pollen deposited offshore Westland, New Zealand
- Author
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Brian Anderson, Matthew T. Ryan, Rewi M. Newnham, Quan Hua, Brent V. Alloway, Andrew P. Rees, S. Louise Callard, Marcus J. Vandergoes, Gavin B. Dunbar, Helen L Neil, and Helen C Bostock
- Subjects
Marine isotope stage ,010506 paleontology ,010504 meteorology & atmospheric sciences ,Pleistocene ,Paleontology ,Fluvial ,01 natural sciences ,law.invention ,law ,Sedimentary rock ,Radiocarbon dating ,Tephra ,Quaternary ,Ecology, Evolution, Behavior and Systematics ,Geology ,0105 earth and related environmental sciences ,Chronology - Abstract
The occurrence of terrestrial palynomorphs in Quaternary marine sedimentary sequences allows for direct land–sea correlations and provides a means for transferring Marine Isotope Stage chronologies to terrestrial records that extend beyond the range of radiocarbon dating. Both of these important applications require an implicit assumption that the lag between pollen release and final deposition on the seafloor – here referred to as source-to-sink residence time – is negligible in relation to the chronological resolution of the sedimentary sequence. Most studies implicitly assume zero lag, and where studies do take palynomorph residence time into account, its magnitude is rarely quantified. In Westland, New Zealand, fluvial transport is the main source of delivery of terrestrial pollen offshore to the adjacent East Tasman Sea. We radiocarbon-dated organic matter carried and deposited by contemporary Westland rivers that drain catchments with varying degrees of disturbance. The ages obtained ranged widely from essentially modern (i.e., − 57 ± 22 cal yr BP) to 3583 ± 188 cal yr BP, suggesting that precisely constraining the residence time in this region is unlikely to be achieved. We also compared the timing of four palynomorph events characterising Westland's late Pleistocene, along with the well-dated Kawakawa/Oruanui Tephra (KOT), between marine core MD06-2991 and four terrestrial records from Westland. Critically, all palynomorph events and the KOT are chronologically indistinguishable with respect to the independently dated marine and terrestrial records, supporting the general principle of transferring the marine chronology onto the terrestrial records in this setting. In other regions, particularly those lacking the high soil production and erosion rates that characterise Westland, we suggest that similar tests of marine residence time should be conducted before assumptions of zero or negligible lag are invoked.
- Published
- 2016
- Full Text
- View/download PDF
147. The Last Glacial Maximum in the central North Island, New Zealand: palaeoclimate inferences from glacier modelling
- Author
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Andrew Mackintosh, Andrew T. Calvert, Shaun R. Eaves, Joerg M. Schaefer, Graham S. Leonard, Alice M. Doughty, Gisela Winckler, Chris E. Conway, Brian Anderson, and Dougal Townsend
- Subjects
lcsh:GE1-350 ,Global and Planetary Change ,geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,lcsh:Environmental protection ,Stratigraphy ,Paleontology ,Last Glacial Maximum ,Glacier ,010502 geochemistry & geophysics ,01 natural sciences ,Proxy (climate) ,lcsh:Environmental pollution ,Volcano ,Moraine ,Close relationship ,Climatology ,lcsh:TD172-193.5 ,lcsh:TD169-171.8 ,Climate model ,Data flow model ,lcsh:Environmental sciences ,Geology ,0105 earth and related environmental sciences - Abstract
Quantitative palaeoclimate reconstructions provide data for evaluating the mechanisms of past, natural climate variability. Geometries of former mountain glaciers, constrained by moraine mapping, afford the opportunity to reconstruct palaeoclimate, due to the close relationship between ice extent and local climate. In this study, we present results from a series of experiments using a 2-D coupled energy balance–ice flow model that investigate the palaeoclimate significance of Last Glacial Maximum moraines within nine catchments in the central North Island, New Zealand. We find that the former ice limits can be simulated when present-day temperatures are reduced by between 4 and 7 °C, if precipitation remains unchanged from present. The spread in the results between the nine catchments is likely to represent the combination of chronological and model uncertainties. The majority of catchments targeted require temperature decreases of 5.1 to 6.3 °C to simulate the former glaciers, which represents our best estimate of the temperature anomaly in the central North Island, New Zealand, during the Last Glacial Maximum. A decrease in precipitation of up to 25 % from present, as suggested by proxy evidence and climate models, increases the magnitude of the required temperature changes by up to 0.8 °C. Glacier model experiments using reconstructed topographies that exclude the volume of post-glacial (
- Published
- 2016
- Full Text
- View/download PDF
148. Paraglacial adjustment of sediment slopes during and immediately after glacial debuttressing
- Author
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Samuel T. McColl, Heather Purdie, Brian Anderson, Emma Cody, and Ian C. Fuller
- Subjects
geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Sediment ,Glacier ,010502 geochemistry & geophysics ,01 natural sciences ,Debris ,Paraglacial ,Period (geology) ,Erosion ,Dead-ice ,Physical geography ,Glacial period ,Geology ,0105 earth and related environmental sciences ,Earth-Surface Processes - Abstract
Daily time lapse imagery and pixel tracking was used to monitor and track spatial and temporal changes in sediment-mantled hillslopes, during and immediately after glacier retreat in the Fox Glacier/Te Moeka o Tuawe valley, New Zealand. Observations from 2014 to 2018 of the Fox Glacier and surrounding hillslopes show hillslope failure is primarily coincident with, and triggered by, glacier retreat with rainfall accelerating movement of the hillslope. During glacier retreat, failure of the hillslope primarily occurred through sediment sliding, internal deformation of the sediment and occasional surficial debris falls, flows and avalanches delivering approximately 9.2 M m3 of sediment directly to the underside of the glacier over the study period with a maximum daily averaged movement of 0.4 m per day of the main sediment mass. Following debuttressing, hillslope failure became dominated by localised rainfall-induced debris flows which initiated gullying of the sediment-mantled slope. Ongoing instability of the slope and associated movement is maintained by toe erosion from the Fox River and melting dead ice, while continued rapid failure is facilitated through localised debris flows. The tracking of temporal and spatial changes of sediment-mantled hillslopes during glacier retreat has shown broad-scale hillslope response to occur quickly within days of rainfall or accelerated glacier retreat, particularly during summer. Debris flows, commonly thought to be a dominant erosion process within paraglacial environments, only occur following complete debuttressing and are supply-limited, only occurring after sediment sliding has occurred. Unlike many other case studies, sediment connectivity immediately following glacier retreat is high due to a lack of storage space and high rainfall inducing mass movements, efficiently delivering hillslope sediments to the proglacial stream channel. Attempts to quantify displaced volumes of sediment from paraglacial systems are likely underestimated due to a) a lack of focus on the early and latter stages of debuttressing b) a reliance on debris flows being a primary transport mechanism, and c) sediment being delivered sub-glacially rather than supra-glacially, further enhancing connectivity.
- Published
- 2020
- Full Text
- View/download PDF
149. Impulsive Energy Transfer from the Magnetosphere to the Ionosphere during Geomagnetic Storms
- Author
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L. J. Zanetti, R. M. Robinson, Haje Korth, and Brian Anderson
- Subjects
Geomagnetic storm ,Energy transfer ,Magnetosphere ,Geophysics ,Ionosphere ,Geology - Published
- 2018
- Full Text
- View/download PDF
150. Modelled glacier equilibrium line altitudes during the mid-Holocene in the southern mid-latitudes
- Author
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Patricio I. Moreno, Andrew Mackintosh, Maisa Rojas, Brian Anderson, Esteban A. Sagredo, and Claudio Bravo
- Subjects
lcsh:GE1-350 ,Global and Planetary Change ,geography ,geography.geographical_feature_category ,lcsh:Environmental protection ,Stratigraphy ,Paleontology ,Glacier ,Forcing (mathematics) ,Snow ,Glacier mass balance ,lcsh:Environmental pollution ,Middle latitudes ,Climatology ,lcsh:TD172-193.5 ,Environmental science ,lcsh:TD169-171.8 ,Precipitation ,Southern Hemisphere ,lcsh:Environmental sciences ,Holocene - Abstract
Glacier behaviour during the mid-Holocene (MH, 6000 years BP) in the Southern Hemisphere provides observational data to constrain our understanding of the origin and propagation of palaeoclimate signals. In this study we examine the climatic forcing of glacier response in the MH by evaluating modelled glacier equilibrium line altitudes (ELAs) and climatic conditions during the MH compared with pre-industrial time (PI, year 1750). We focus on the middle latitudes of the Southern Hemisphere, specifically Patagonia and the South Island of New Zealand. Climate conditions for the MH were obtained from PMIP2 model simulations, which in turn were used to force a simple glacier mass balance model to simulate changes in ELA. In Patagonia, the models simulate colder conditions during the MH in austral summer (−0.2 °C), autumn (−0.5 °C), and winter (−0.4), and warmer temperatures (0.2 °C) during spring. In the Southern Alps the models show colder MH conditions in autumn (−0.7 °C) and winter (−0.4 °C), warmer conditions in spring (0.3 °C), and no significant change in summer temperature. Precipitation does not show significant changes but exhibits a seasonal shift, with less precipitation from April to September and more precipitation from October to April during the MH in both regions. The mass balance model simulates a climatic ELA that is 15–33 m lower during the MH compared with PI conditions. We suggest that the main causes of this difference are driven mainly by colder temperatures associated with the MH simulation. Differences in temperature have a dual effect on glacier mass balance: (i) less energy is available for ablation during summer and early autumn and (ii) lower temperatures cause more precipitation to fall as snow rather than rain in late autumn and winter, resulting in more accumulation and higher surface albedo. For these reasons, we postulate that the modelled ELA changes, although small, may help to explain larger glacier extents observed by 6000 years BP in South America and New Zealand.
- Published
- 2018
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