101. Recent Syntheses and Strategies toward Polycyclic Gelsemium Alkaloids.
- Author
-
Ghosh A and Carter RG
- Subjects
- Alkaloids chemistry, Biological Products chemical synthesis, Biological Products chemistry, Bridged Bicyclo Compounds chemical synthesis, Bridged Bicyclo Compounds chemistry, Oxindoles chemistry, Polycyclic Compounds chemistry, Alkaloids chemical synthesis, Chemistry Techniques, Synthetic methods, Gelsemium chemistry, Oxindoles chemical synthesis, Polycyclic Compounds chemical synthesis
- Abstract
This Minireview is focused on an in-depth discussion of comparative strategies to construct the gelsemine and gelsedine classes of the gelsemium alkaloids. This document highlights the diversity of strategies used to access specific motifs found within these targets: a) the fused "[3.2.1]bicycle" (in gelsemine) and "oxabicycle" (in gelsedine class); b) the "piroxindole" moiety with C7 quaternary center; c) the "N-heterocycles" and d) the "THP" moiety with C20 quaternary center (in gelsemine)., (© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)
- Published
- 2019
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