101. Mixed follicular and parafollicular thyroid carcinoma.
- Author
-
Vitri P, Galimberti A, De Pasquale L, Vago L, Boldorini R, and Bastagli A
- Subjects
- Adenocarcinoma, Follicular drug therapy, Adenocarcinoma, Follicular surgery, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Calcitonin analysis, Carcinoma, Medullary drug therapy, Carcinoma, Medullary surgery, Cell Division, Cytoplasmic Granules pathology, Fatal Outcome, Humans, Male, Microvilli pathology, Middle Aged, Neoplasms, Second Primary drug therapy, Neoplasms, Second Primary surgery, Palliative Care, Thyroglobulin analysis, Thyroid Neoplasms drug therapy, Thyroid Neoplasms surgery, Adenocarcinoma, Follicular pathology, Carcinoma, Medullary pathology, Neoplasms, Second Primary pathology, Thyroid Neoplasms pathology
- Abstract
A rare case of mixed follicular-parafollicular thyroid carcinoma which occurred in a 50-year-old man, is reported. The ultrastructural aspects of the tumor showed: a biphasic growth pattern with microfolliculi and solid areas; the coexpression of thyroglobulin and calcitonin antigens in the same follicle-like structures; the presence of neuroendocrine granules, microvilli and intracytoplasmic canaliculi bordered by microvilli. These characteristics lead us to a diagnosis of mixed follicular-parafollicular thyroid carcinoma.
- Published
- 1999