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101. Improved rates of secondary prevention medication following hospitalisation for an acute coronary syndrome (ACS) in New Zealand (NZ): Results from the NZ ACS national audits of 2002, 2007 and 2012

Author

Ellis, C., primary, Gamble, G., additional, Devlin, G., additional, Elliott, J., additional, Hamer, A., additional, Matsis, P., additional, Williams, M., additional, Troughton, R., additional, Mann, S., additional, French, J., additional, Richards, A., additional, and White, H., additional

Published
2014
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103. Health equity in the New Zealand health care system: a national survey

Author

Sheridan, NF, Kenealy, TW, Connolly, MJ, Mahony, F, Barber, PA, Boyd, MA, Carswell, P, Clinton, J, Devlin, G, Doughty, R, Dyall, L, Kerse, N, Kolbe, J, Lawrenson, R, Moffitt, A, Sheridan, NF, Kenealy, TW, Connolly, MJ, Mahony, F, Barber, PA, Boyd, MA, Carswell, P, Clinton, J, Devlin, G, Doughty, R, Dyall, L, Kerse, N, Kolbe, J, Lawrenson, R, and Moffitt, A

Abstract

INTRODUCTION: In all countries people experience different social circumstances that result in avoidable differences in health. In New Zealand, Māori, Pacific peoples, and those with lower socioeconomic status experience higher levels of chronic illness, which is the leading cause of mortality, morbidity and inequitable health outcomes. Whilst the health system can enable a fairer distribution of good health, limited national data is available to measure health equity. Therefore, we sought to find out whether health services in New Zealand were equitable by measuring the level of development of components of chronic care management systems across district health boards. Variation in provision by geography, condition or ethnicity can be interpreted as inequitable. METHODS: A national survey of district health boards (DHBs) was undertaken on macro approaches to chronic condition management with detail on cardiovascular disease, chronic obstructive pulmonary disease, congestive heart failure, stroke and diabetes. Additional data from expert informant interviews on program reach and the cultural needs of Māori and Pacific peoples was sought. Survey data were analyzed on dimensions of health equity relevant to strategic planning and program delivery. Results are presented as descriptive statistics and free text. Interviews were transcribed and NVivo 8 software supported a general inductive approach to identify common themes. RESULTS: Survey responses were received from the majority of DHBs (15/21), some PHOs (21/84) and 31 expert informants. Measuring, monitoring and targeting equity is not systematically undertaken. The Health Equity Assessment Tool is used in strategic planning but not in decisions about implementing or monitoring disease programs. Variable implementation of evidence-based practices in disease management and multiple funding streams made program implementation difficult. Equity for Māori is embedded in policy, this is not so for other ethnic groups or

Published
2011

104. The quaternary organization and dynamics of the molecular chaperone HSP26 are thermally regulated

Author

Benesch, J. L., Aquilina, Andrew, Baldwin, Andrew, Rekas, Agata, Stengel, Florian, Lindner, Robyn, Basha, Eman, Devlin, G., Horwitz, J., Vierling, Elizabeth, Carver, John, Robinson, C. V., Benesch, J. L., Aquilina, Andrew, Baldwin, Andrew, Rekas, Agata, Stengel, Florian, Lindner, Robyn, Basha, Eman, Devlin, G., Horwitz, J., Vierling, Elizabeth, Carver, John, and Robinson, C. V.

Abstract

The function of ScHSP26 is thermally controlled: the heat shock that causes the destabilization of target proteins leads to its activation as a molecular chaperone. We investigate the structural and dynamical properties of ScHSP26 oligomers through a combination of multiangle light scattering, fluorescence spectroscopy, NMR spectroscopy, and mass spectrometry. We show that ScHSP26 exists as a heterogeneous oligomeric ensemble at room temperature. At heat-shock temperatures, two shifts in equilibria are observed: toward dissociation and to larger oligomers. We examine the quaternary dynamics of these oligomers by investigating the rate of exchange of subunits between them and find that this not only increases with temperature but proceeds via two separate processes. This is consistent with a conformational change of the oligomers at elevated temperatures which regulates the disassembly rates of this thermally activated protein.

Published
2010

105. Determining the zoonotic significance of Giardia and Cryptosporidium in Australian dogs and cats

Author

Palmer, C.S., Traub, R.J., Robertson, I.D., Devlin, G., Rees, R., Thompson, R.C.A., Palmer, C.S., Traub, R.J., Robertson, I.D., Devlin, G., Rees, R., and Thompson, R.C.A.

Abstract

In a recent study of intestinal parasites in dogs and cats in Australia, Giardia was found to be the most prevalent parasite in dogs. The aim of the current study through the use of molecular tools was to determine the zoonotic significance of the Giardia and Cryptosporidium isolates recovered from dogs and cats during the Australian study. Of the isolates successfully amplified all but one of the Giardia from dogs was either Assemblage C and/or D, with one Assemblage A. Of the cat samples amplified all but one were Assemblage F, with one Assemblage D. We hypothesize that the lack of zoonotic Giardia Assemblages recovered is a result of their being a low prevalence of Giardia in the human population. The Cryptosporidium recovered from dogs and cats was determined to be C. canis and C. felis, respectively, a finding which supports growing evidence that Cryptosporidium in companion animals is of limited public health significance to healthy people.

Published
2008

107. Significant Delays to Access Cardiac Angiography for Acute Coronary Syndrome (ACS) Patients in New Zealand (NZ): A Comparison of the National 2002, 2007 and (Snapshot) 2012 ACS Audits

Author

Ellis, C.J., primary, Gamble, G.D., additional, Devlin, G., additional, Elliott, J.M., additional, Matsis, P., additional, Williams, M.J.A., additional, Hamer, A., additional, Mann, S., additional, French, J.K., additional, Richards, A.M., additional, Troughton, R., additional, and White, H.D., additional

Published
2013
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109. Improving Interventional Management of Acute Coronary Syndrome (ACS) Patients in New Zealand (NZ): A Comparison of the 2002, 2007 and 2012 National ACS Audits

Author

Ellis, C.J., primary, Gamble, G.D., additional, Hamer, A., additional, Matsis, P., additional, Williams, M.J.A., additional, Devlin, G., additional, Elliott, J.M., additional, Mann, S., additional, French, J.K., additional, Richards, A.M., additional, Troughton, R., additional, and White, H.D., additional

Published
2013
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120. STEMI Care in Australia and New Zealand: Results From The Australia and New Zealand SNAPSHOT ACS

Author

French, J., primary, Hammett, C., additional, Ellis, C., additional, Devlin, G., additional, Williams, M., additional, Elliott, J., additional, Rankin, J., additional, Turnbull, F., additional, Thompson, S., additional, Lefkovits, J., additional, Parker, H., additional, Lintern, K., additional, Howell, T., additional, Brieger, D., additional, Carr, B., additional, and Chew, D., additional

Published
2013
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126. Is the Mortality Risk Following an Acute Coronary Syndrome (ACS) Admission to a Non-intervention Centre Related to Access to Cardiac Angiography? Eighteen Month Follow-up of the 2002/2007 New Zealand (NZ) ACS Audits

Author

Ellis, CJ., primary, Gamble, G.D., additional, Hamer, A., additional, Devlin, G., additional, Elliott, J.M., additional, Matsis, P., additional, Williams, M.J.A., additional, Mann, S., additional, French, J.K., additional, Richards, A.M., additional, and White, H.D., additional

Published
2012
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133. Is the Mortality Risk Following an Acute Coronary Syndrome (ACS) Admission to a Non-Intervention Centre Related to Access to Cardiac Angiography? 18 Month Follow-Up of the 2002/2007 New Zealand (NZ) ACS Audits

Author

Ellis, C., primary, Gamble, G., additional, Hamer, A., additional, Devlin, G., additional, Elliott, J., additional, Matsis, P., additional, Williams, M., additional, Mann, S., additional, French, J., additional, Richards, M., additional, and White, H., additional

Published
2012
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