101. T cell non-Hodgkin's lymphoma with colesional mucormycosis presenting as palatal perforation: a case report.
- Author
-
Khan AA, Garg A, Dhawan S, Agarwal PK, Siraj F, and Aggarwal S
- Subjects
- Amphotericin B therapeutic use, Antifungal Agents therapeutic use, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Combined Modality Therapy, Cyclophosphamide administration & dosage, Debridement, Doxorubicin administration & dosage, Humans, Lymphoma, T-Cell pathology, Lymphoma, T-Cell therapy, Male, Middle Aged, Mucormycosis therapy, Opportunistic Infections therapy, Palatal Neoplasms pathology, Palatal Neoplasms therapy, Palate, Hard pathology, Prednisolone administration & dosage, Rhinitis therapy, Vincristine administration & dosage, Lymphoma, T-Cell complications, Lymphoma, T-Cell diagnosis, Mucormycosis complications, Mucormycosis diagnosis, Mucormycosis pathology, Nasal Cavity pathology, Opportunistic Infections complications, Opportunistic Infections diagnosis, Opportunistic Infections pathology, Palatal Neoplasms complications, Palatal Neoplasms diagnosis, Rhinitis complications, Rhinitis diagnosis, Rhinitis pathology
- Abstract
Non-Hodgkin's lymphoma (NHL) is predominantly a disease of lymph nodes, but extranodal involvement is not very uncommon. Palatal involvement by NHL is rare. Mucormycosis is a devastating fungal infection commonly seen in immunocompromised individuals, including those with NHL, but it is affecting the same region has been reported very rarely. Simultaneous infiltration of hard palate by NHL and mucormycosis is extremely unusual. Herein we describe a patient who presented with palatal hole with histopathological examination revealing presence of lymphoma with colesional mucormycosis. The identification of mucor was vital because chemotherapy alone in the absence of antifungals would have had devastating consequences as the mortality of untreated mucormycosis is high.
- Published
- 2012