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613 results on '"Fritze, J."'

101. Psychopharmaka-Verordnungen

Author

Fritze J

Subjects
Drug, medicine.medical_specialty, business.industry, media_common.quotation_subject, General Medicine, Psychiatry and Mental health, Psychotropic drug, Neurology, Family medicine, Medicine, Neurology (clinical), Medical prescription, business, media_common
Published
2002

103. Visionen und Realität von HTA

Author

Fritze, J

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

[for full text, please go to the a.m. URL], 10. Symposium Health Technology Assessment

Published
2010
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107. Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder

Author

Vg, Hösing, Schirmacher A, Kuhlenbäumer G, Freitag C, Sand P, Schlesiger C, Jacob C, Fritze J, Franke P, Rietschel M, Garritsen H, Markus Nöthen, Fimmers R, Stögbauer F, and Deckert J

Subjects
Adult, Male, Polymorphism, Genetic, Genotype, Genetic Variation, Middle Aged, Receptor, Cholecystokinin B, Gene Frequency, Confidence Intervals, Odds Ratio, Humans, Panic Disorder, Female, Cholecystokinin
Abstract

Panic disorder like other neuropsychiatric disorders is believed to be caused by multiple psychosocial and biological factors. Several lines of evidence point to a role for the peptide neurotransmitter cholecystokinin in the pathogenesis of panic disorder. We therefore determined the allele and genotype frequencies of a single nucleotide polymorphism in the CCK gene (-36CT) and one CT repeat polymorphism in the CCK-B-receptor gene in a German panic disorder sample (n = 115 for CCK gene polymorphism, n = 111 for CCK-B-receptor polymorphism) and compared them with gender and age matched controls. The length of the polymorphic CT repeat alleles varies between 146 bp and 180 bp. We first analysed the results by a permutation test which provided evidence for heterogeneity between patients and controls (p=0.002). We then analysed the data as a di-allelic polymorphism with a short (146-162bp) and a long (164-180bp) allele and as a tetra-allelic polymorphism with 4 alleles (146-154bp, 156-162bp, 164-170bp, 172-180bp). In the di-allelic analysis as well as in the tetra-allelic analysis there was an excess of the longer allele (p = 0.001) or the two longer alleles (p = 0.041) respectively in patients with panic disorder. No difference between groups was observed for the -36CT polymorphism. Our findings are consistent with the notion that genetic variation in the CCK neurotransmitter system contributes to the pathogenesis of panic disorder.

Published
2004

114. Cholinergic neurotransmission seems not to be involved in depression but possibly in personality

Author

Fritze, J, Lanczik, M, Sofic, E, Struck, M, and Riederer, P

Subjects
Adult, Male, Depressive Disorder, Adolescent, Dose-Response Relationship, Drug, Physostigmine, Mianserin, Middle Aged, Synaptic Transmission, Acetylcholine, Drug Administration Schedule, Biperiden, Viloxazine, Cholinergic Fibers, Double-Blind Method, Humans, Drug Therapy, Combination, Female, Arousal, Research Article, Aged, Personality
Abstract

Concordant with the adrenergic-cholinergic imbalance hypothesis of affective psychosis, there is a cholinergic supersensitivity in depression. Thus, the anticholinergic properties of some antidepressants might contribute to their efficacy. However, in the present double-blind studies (n = 20) with mianserin and viloxazine, respectively, which lack anticholinergic properties, adjunctive treatment with the anticholinergic biperiden versus placebo did not enhance the antidepressive efficacy. Therefore, we hypothesized that cholinergic supersensitivity might be linked to some possibly predisposing dimension of personality. Indeed, in healthy male volunteers (n = 11) the behavioral and cardiovascular sensitivity to physostigmine correlated significantly with "irritability" and "emotional lability" as well as with habitually passive strategies in stress coping. The rise in plasma cortisol and norepinephrine correlated with "retardation"; that of epinephrine with active coping. Thus, the cholinergic supersensitivity in affective psychoses might be linked to a personality dimension like stress sensitivity rather than to the diagnostic category itself.

Published
1995

118. Neuropeptide S receptor gene — converging evidence for a role in panic disorder

Author

Domschke, K, primary, Reif, A, additional, Weber, H, additional, Richter, J, additional, Hohoff, C, additional, Ohrmann, P, additional, Pedersen, A, additional, Bauer, J, additional, Suslow, T, additional, Kugel, H, additional, Heindel, W, additional, Baumann, C, additional, Klauke, B, additional, Jacob, C, additional, Maier, W, additional, Fritze, J, additional, Bandelow, B, additional, Krakowitzky, P, additional, Rothermundt, M, additional, Erhardt, A, additional, Binder, E B, additional, Holsboer, F, additional, Gerlach, A L, additional, Kircher, T, additional, Lang, T, additional, Alpers, G W, additional, Ströhle, A, additional, Fehm, L, additional, Gloster, A T, additional, Wittchen, H-U, additional, Arolt, V, additional, Pauli, P, additional, Hamm, A, additional, and Deckert, J, additional

Published
2010
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122. Deutsche Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde (DGPPN):¶Die Krankenhausplanung der Länder muss Ausbau der gemeindenahen Psychiatrie im Sinne der Entstigmatisierung vorantreiben

Author

Fritze J, Schmauss M, Psychotherapie und Nervenheilkunde Deutsche Gesellschaft für Psychiatrie, and Sass H

Subjects
medicine.medical_specialty, Neurology, business.industry, General Medicine, National planning, language.human_language, German, Psychiatry and Mental health, Family medicine, medicine, language, Neurology (clinical), Psychiatry, business
Published
2001

131. Investigation of the DAOA/G30 locus in panic disorder

Author

Schumacher, J, primary, Abou Jamra, R, additional, Becker, T, additional, Klopp, N, additional, Franke, P, additional, Jacob, C, additional, Sand, P, additional, Fritze, J, additional, Ohlraun, S, additional, Schulze, T G, additional, Rietschel, M, additional, Illig, T, additional, Propping, P, additional, Cichon, S, additional, Deckert, J, additional, and Nöthen, M M, additional

Published
2004
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143. Human nuclear transcription factor gene CREM: Genomic organization, mutation screening, and association analysis in panic disorder

Author

Domschke, K., primary, Kuhlenbäumer, G., additional, Schirmacher, A., additional, Lorenzi, C., additional, Armengol, L., additional, DiBella, D., additional, Gratacos, M., additional, Garritsen, H.S., additional, Nöthen, M.M., additional, Franke, P., additional, Sand, P., additional, Fritze, J., additional, Perez, G., additional, Maier, W., additional, Sibrowski, W., additional, Estivill, X., additional, Bellodi, L., additional, Ringelstein, E.B., additional, Arolt, V., additional, Martin‐Santos, R., additional, Catalano, M., additional, Stögbauer, F., additional, and Deckert, J., additional

Published
2002
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145. Estrogen receptor 1 gene (ESR1) variants in panic disorder

Author

Sand, P.G., primary, Schlurmann, K., additional, Luckhaus, C., additional, Götz, M., additional, Stöber, G., additional, Lesch, K.-P., additional, Riederer, P., additional, Franke, P., additional, Maier, W., additional, Nöthen, M.M., additional, Propping, P., additional, Fritze, J., additional, and Deckert, J., additional

Published
2002
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149. Exonic variants of the GABAB receptor gene and panic disorder

Author

Sand, P. G., primary, Godau, C., additional, Riederer, P., additional, Peters, C., additional, Franke, P., additional, Nöthen, M. M., additional, Stöber, G., additional, Fritze, J., additional, Maier, W., additional, Propping, P., additional, Lesch, KP., additional, Riess, O., additional, Sander, T., additional, Beckmann, H., additional, and Deckert, J., additional

Published
2000
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