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1,233 results on '"Gao, Jianhua"'

114. Synthesis of High‐Fluorescent Diphenyl−anthracene Derivatives and Application in Detection of Nitroaromatic Explosives and Fingerprint Identification.

Author

Lai, Jiagen, Pan, Qinghua, Ma, Qingfang, Shan, Xiaoyue, Chen, Lian, and Gao, Jianhua

Subjects
HUMAN fingerprints, EXPLOSIVES detection, ANTHRACENE derivatives, FLUORESCENCE resonance energy transfer, FORENSIC fingerprinting, PICRIC acid
Abstract

The development of high‐intensity fluorescent materials is always the focuses and forefront projects because of their important applications in displays, sensing and detection fields. In recent years, the detection of explosives has attracted increasing attention due to security and counterterrorism issues. Herein, two diphenyl−anthracene (DPA) derivatives were designed and synthesized by introducing strong electron withdrawing fluorine atoms and cyano‐groups to DPA, which exhibited strong fluorescence both in the solution and solid phase with the absolute quantum yields up to 70.4 % and 45.9 % respectively. The detection behavior of nitroaromatic explosives such as picric acid (PA), 2,4,6‐trinitrotoluene (TNT) and 3‐Nitropropionic acid (3‐NP) also shows good sensitivity with the quenching constant as high as 6.3×104 L mol−1. Theoretical calculation demonstrates that the fluorescence quenching behavior of the two DPA derivatives is caused by the behavior of photoinduced electron transfer (PET) and the resonance energy transfer (RET) studies explained the higher sensitivity and selectivity of both compounds towards PA than other nitro‐containing explosives. Furthermore, the strong solid‐state fluorescence of the DPA derivatives also shows excellent advantages in enhancing latent fingerprint recognition. [ABSTRACT FROM AUTHOR]

Published
2024
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115. Pathological characteristics of breast nodules after large‐volume fat grafting for breast augmentation.

Author

Li, Yibao, Yao, Yao, Li, Jian, He, Yunfan, Xu, Mimi, Liu, Kaiyang, You, Xin, Chen, Kaiqi, Lu, Feng, Gao, Jianhua, and Liao, Yunjun

Subjects
BREAST biopsy, FAT, ADIPOSE tissues, BLOOD vessels, DRUG target
Abstract

Background: The complications of large‐volume fat grafting (LVFG) for breast augmentation remain unpredictable and include palpable breast nodules, oil cysts, and calcifications. Aims: This study was aimed to provide an optimal treatment option for breast nodules after LVFG and evaluate their pathological characteristics. Patients/Methods: We effectively performed complete resection of breast nodules in 29 patients after LVFG using a minimal skin incision with the vacuum‐assisted breast biopsy (VABB) system under ultrasound guidance. And we further carried on histologic examination of excised nodules and evaluated their pathological characteristics. Results: The breast nodules were excised thoroughly with cosmetic effect satisfactorily. Interestingly, subsequent histologic examination showed that type I and VI collagens were strongly expressed in the fibrotic area and type IV collagen were positively expressed around the blood vessel. Furthermore, we found that the type VI collagen+ area appeared around mac2+ macrophages and α‐SMA+ myofibroblasts. Conclusions: The VABB system may be the optimal treatment option for breast nodules after LVFG. And type VI collagens may serve as a biomarker of grafted adipose tissue fibrosis. The relationship between macrophages, fibroblasts, and collagen formation may be therapeutic targets for regulating fibrosis. [ABSTRACT FROM AUTHOR]

Published
2023
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116. Corrigendum to ‘Methoxy polyethylene glycol modification promotes adipogenesis by inducing the production of regulatory T cells in xenogeneic acellular adipose matrix’ [Materials Today Bio 12 (2021) 100161]

Author

Liu, Kaiyang, primary, He, Yunfan, additional, Yao, Yao, additional, Zhang, Yuchen, additional, Cai, Zihan, additional, Ru, Jiangjiang, additional, Zhang, Xiangdong, additional, Jin, Xiaoxuan, additional, Xu, Mimi, additional, Li, Yibao, additional, Ma, Qizhuan, additional, Gao, Jianhua, additional, and Lu, Feng, additional

Published
2023
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125. Author correction to ‘DNA damage repair promotion in colonic epithelial cells by andrographolide downregulated cGAS‒STING pathway activation and contributed to the relief of CPT-11-induced intestinal mucositis’ [Acta Pharmaceutica Sinica B 12 (2022) 262–273]

Author

Wang, Yuanyuan, primary, Wei, Bin, additional, Wang, Danping, additional, Wu, Jingjing, additional, Gao, Jianhua, additional, Zhong, Haiqing, additional, Sun, Yang, additional, Xu, Qiang, additional, Liu, Wen, additional, Gu, Yanhong, additional, and Guo, Wenjie, additional

Published
2023
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135. Decoding the biological properties and transcriptomic landscapes of human natural killer cells derived from bone marrow and umbilical cord blood

Author

Xie, Baoguo, Zhang, Leisheng, Gao, Jianhua, Wang, Ti’er, Liu, Min, Feng, Xiaoming, Xu, Xianghong, Ma, Shixun, Cai, Hui, Guo, Tiankang, Huang, Weibin, Tu, Xiaoyan, Wang, Shuling, Yang, Hongju, Fang, Yihu, Li, Feifei, and Chen, Cunrong

Subjects
Original Article
Abstract

Longitudinal studies have highlighted allogeneic natural killer (NK) cell-based cytotherapy for cancer immunosurveillance and immunotherapy, yet the deficiency of systematic and detailed comparison of NK cells from candidate sources including umbilical cord blood (UC) and bone marrow (BM) largely hinders the large-scale application. Herein, we isolated resident NK cells (rUC-NK, rBM-NK) from mononuclear cells (MNC), and analyzed the corresponding expanded NK cell counterparts (eUC-NK, eBM-NK). Then, the eUC-NK and eBM-NK were turned to multifaceted bioinformatics from the aspects of gene expression profiling and genetic variations. The percentages of total or activated NK cells in rBM-NK group were approximate 2-fold higher over those in the rUC-NK group, respectively. Instead, the proportion of total NK cells in eUC-NK was higher than that in the eBM-NK group, and in particular, the CD25(+) memory-like NK cell subset. Furthermore, eUC-NK and eBM-NK manifested multidimensional similarities and diversities in gene expression pattern and genetic spectrum, whereas both eUC-NK and eBM-NK exhibited effective tumor killing capacity. Collectively, we dissected the cellular and transcriptomic signatures of NK cells generated from UC-MNC and BM-MNC, which supplied new literature for further exploring the characteristics of the indicated NK cells and would benefit the clinical application for cancer immunotherapy in future.

Published
2023

138. A Novel Bug Report Extraction Approach

Author

Lin, Tao, Gao, Jianhua, Fu, Xue, Lin, Yan, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Weikum, Gerhard, Series editor, Wang, Guojin, editor, Zomaya, Albert, editor, Martinez, Gregorio, editor, and Li, Kenli, editor

Published
2015
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142. Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial

Author

Wang, Yongjun, primary, Li, Shuya, additional, Pan, Yuesong, additional, Li, Hao, additional, Parsons, Mark W, additional, Campbell, Bruce C V, additional, Schwamm, Lee H, additional, Fisher, Marc, additional, Che, Fengyuan, additional, Dai, Hongguo, additional, Li, Deyang, additional, Li, Runhui, additional, Wang, Junhai, additional, Wang, Yilong, additional, Zhao, Xingquan, additional, Li, Zixiao, additional, Zheng, Huaguang, additional, Xiong, Yunyun, additional, Meng, Xia, additional, Wang, Dong, additional, Wang, Yongjun, additional, Chen, Shengli, additional, Deng, Dan, additional, Zhang, Hong, additional, Chen, Huisheng, additional, Zhang, Hongwei, additional, Wu, Yiping, additional, Liu, Hong, additional, Lu, Guozhi, additional, Zhao, Liandong, additional, Zhu, Runxiu, additional, Liu, Ying, additional, Yi, Fei, additional, Gao, Jianhua, additional, Hao, Junfang, additional, Cai, Xueli, additional, Duan, Zhihui, additional, Yu, Hong, additional, Wei, Tongguo, additional, Tang, Yufeng, additional, Peng, Zhaolong, additional, Zhang, Baochao, additional, Song, Yan, additional, Chen, Xiaofei, additional, Liu, Yunlin, additional, Liu, Jing, additional, Zhao, Weili, additional, Wei, Xiue, additional, Xue, Qian, additional, Liu, Xuewen, additional, Yang, Yi, additional, zhao, Chuansheng, additional, Chen, Jun, additional, Sui, Yi, additional, Sheng, Guizhi, additional, Zhang, Yun, additional, Liu, Junyan, additional, Zhang, Lianhuan, additional, Wang, Weiwei, additional, Guo, Zhiyong, additional, Hu, Renping, additional, Chen, Guofang, additional, Liang, Zhigang, additional, Chen, Junbin, additional, Xia, Lei, additional, and Long, Zhihua, additional

Published
2023
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