Search

Your search keyword '"Goldoni, Matteo"' showing total 580 results
Start Over Author "Goldoni, Matteo"
580 results on '"Goldoni, Matteo"'

101. Influence of condensation temperature on selected exhaled breath parameters

Author

Manini Paola, Poli Diana, Andreoli Roberta, Caglieri Andrea, Goldoni Matteo, Vettori Maria, Corradi Massimo, and Mutti Antonio

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Abstract Background The effects of changes in cooling temperature on biomarker levels in exhaled breath condensate have been little investigated. The aim of the study was to test the effect of condensation temperature on the parameters of exhaled breath condensate and the levels of selected biomarkers. Methods Exhaled breath condensate was collected from 24 healthy subjects at temperatures of -10, -5, 0 and +5 C degrees. Selected parameters (condensed volume and conductivity) and biomarkers (hydrogen peroxide, malondialdehyde) were measured. Results There was a progressive increase in hydrogen peroxide and malondialdehyde concentrations, and condensate conductivity as the cooling temperature increased; total condensate volume increased as the cooling temperature decreased. Conclusion The cooling temperature of exhaled breath condensate collection influenced selected biomarkers and potential normalizing factors (particularly conductivity) in different ways ex vivo. The temperature of exhaled breath condensate collection should be controlled and reported.

Published
2005
Full Text
View/download PDF

102. Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study

Author

Acampa Olga, Goldoni Matteo, Corradi Massimo, Carbognani Paolo, Poli Diana, Balbi Bruno, Bianchi Luca, Rusca Michele, and Mutti Antonio

Subjects
Diseases of the respiratory system, RC705-779
Abstract

Abstract Background Non-invasive diagnostic strategies aimed at identifying biomarkers of lung cancer are of great interest for early cancer detection. The aim of this study was to set up a new method for identifying and quantifying volatile organic compounds (VOCs) in exhaled air of patients with non-small cells lung cancer (NSCLC), by comparing the levels with those obtained from healthy smokers and non-smokers, and patients with chronic obstructive pulmonary disease. The VOC collection and analyses were repeated three weeks after the NSCLC patients underwent lung surgery. Methods The subjects' breath was collected in a Teflon® bulb that traps the last portion of single slow vital capacity. The 13 VOCs selected for this study were concentrated using a solid phase microextraction technique and subsequently analysed by means of gas cromatography/mass spectrometry. Results The levels of the selected VOCs ranged from 10-12 M for styrene to 10-9 M for isoprene. None of VOCs alone discriminated the study groups, and so it was not possible to identify one single chemical compound as a specific lung cancer biomarker. However, multinomial logistic regression analysis showed that VOC profile can correctly classify about 80 % of cases. Only isoprene and decane levels significantly decreased after surgery. Conclusion As the combination of the 13 VOCs allowed the correct classification of the cases into groups, together with conventional diagnostic approaches, VOC analysis could be used as a complementary test for the early diagnosis of lung cancer. Its possible use in the follow-up of operated patients cannot be recommended on the basis of the results of our short-term nested study.

Published
2005
Full Text
View/download PDF

106. Adalimumab-Based Treatment Versus Disease-Modifying Antirheumatic Drugs for Venous Thrombosis in Behçet's Syndrome

Author

Emmi, Giacomo, primary, Vitale, Antonio, additional, Silvestri, Elena, additional, Boddi, Maria, additional, Becatti, Matteo, additional, Fiorillo, Claudia, additional, Fabiani, Claudia, additional, Frediani, Bruno, additional, Emmi, Lorenzo, additional, Di Scala, Gerardo, additional, Goldoni, Matteo, additional, Bettiol, Alessandra, additional, Vaglio, Augusto, additional, Cantarini, Luca, additional, and Prisco, Domenico, additional

Published
2018
Full Text
View/download PDF

109. Low PD-1 Expression in Cytotoxic CD8+ Tumor-Infiltrating Lymphocytes Confers an Immune-Privileged Tissue Microenvironment in NSCLC with a Prognostic and Predictive Value

Author

Mazzaschi, Giulia, primary, Madeddu, Denise, additional, Falco, Angela, additional, Bocchialini, Giovanni, additional, Goldoni, Matteo, additional, Sogni, Francesco, additional, Armani, Giovanna, additional, Lagrasta, Costanza Annamaria, additional, Lorusso, Bruno, additional, Mangiaracina, Chiara, additional, Vilella, Rocchina, additional, Frati, Caterina, additional, Alfieri, Roberta, additional, Ampollini, Luca, additional, Veneziani, Michele, additional, Silini, Enrico Maria, additional, Ardizzoni, Andrea, additional, Urbanek, Konrad, additional, Aversa, Franco, additional, Quaini, Federico, additional, and Tiseo, Marcello, additional

Published
2018
Full Text
View/download PDF

110. Blood and lymphatic vessels contribute to the impact of the immune microenvironment on clinical outcome in non-small-cell lung cancer†

Author

Armani, Giovanna, primary, Madeddu, Denise, additional, Mazzaschi, Giulia, additional, Bocchialini, Giovanni, additional, Sogni, Francesco, additional, Frati, Caterina, additional, Lorusso, Bruno, additional, Falco, Angela, additional, Lagrasta, Costanza Annamaria, additional, Cavalli, Stefano, additional, Mangiaracina, Chiara, additional, Vilella, Rocchina, additional, Becchi, Gabriella, additional, Gnetti, Letizia, additional, Corradini, Emilia, additional, Quaini, Eugenio, additional, Urbanek, Konrad, additional, Goldoni, Matteo, additional, Carbognani, Paolo, additional, Ampollini, Luca, additional, and Quaini, Federico, additional

Published
2018
Full Text
View/download PDF

111. Neutrophil Activation Promotes Fibrinogen Oxidation and Thrombus Formation in Behçet’s Disease

Author

Becatti, Matteo, Emmi, Giacomo, Silvestri, Elena, Bruschi, Giulia, Ciucciarelli, Lucia, Squatrito, Danilo, Vaglio, Augusto, Taddei, Niccolo', Abbate, Rosanna, Emmi, Lorenzo, Goldoni, Matteo, Fiorillo, Claudia, and Prisco, Domenico

Subjects
Behçet's disease, fibrinogen, inflammation, oxidative stress, thrombosis, Physiology (medical), Cardiology and Cardiovascular Medicine
Published
2016

112. Prevalence of overweight and cardiovascular risk factors in rural and urban children from Central Asia: the Kazakhstan Health and Nutrition Examination Survey

Author

Facchini, Fiorenzo, Fiori, Giovanni, Bedogni, Giorgio, Galletti, Livia, Rizzoli, Sara, Goldoni, Matteo, Belcastro, Maria Giovanna, Ismagulov, Orazak, Ismagulova, Ainagul, Sharmanov, Turegeldy, and Tsoy, Igor

Subjects
Kazakhstan -- Health aspects, Cardiovascular diseases -- Risk factors, Obesity -- Risk factors, Children -- Health aspects, Children -- Evaluation, Biological sciences
Abstract

Anthropometry, blood pressure, fasting blood cholesterol and glucose were measured in children in Kazakhstan to see if they carry the risk of an epidemic of obesity and cardiovascular disease. The findings showed that overweight risk and cardiovascular risk factors were presently less in children living in Kazakhstan.

Published
2007

114. Brief Report: Rituximab for the Treatment of Adult‐Onset IgA Vasculitis (Henoch‐Schönlein)

Author

Maritati, Federica, primary, Fenoglio, Roberta, additional, Pillebout, Evangeline, additional, Emmi, Giacomo, additional, Urban, Maria L., additional, Rocco, Rossana, additional, Nicastro, Maria, additional, Incerti, Monia, additional, Goldoni, Matteo, additional, Trivioli, Giorgio, additional, Silvestri, Elena, additional, Mohammad, Aladdin J., additional, Jayne, David, additional, Eriksson, Per, additional, Segelmark, Mårten, additional, Novikov, Pavel, additional, Harris, Helen, additional, Roccatello, Dario, additional, and Vaglio, Augusto, additional

Published
2017
Full Text
View/download PDF

115. Bone marrow Dikkopf‐1 levels are a new independent risk factor for progression in patients with smouldering myeloma

Author

Dalla Palma, Benedetta, primary, Marchica, Valentina, additional, Pedrazzoni, Mario, additional, Accardi, Fabrizio, additional, Notarfranchi, Laura, additional, Goldoni, Matteo, additional, De Luca, Federica, additional, Costa, Federica, additional, Storti, Paola, additional, Toscani, Denise, additional, Sammarelli, Gabriella, additional, Bonomini, Sabrina, additional, Aversa, Franco, additional, and Giuliani, Nicola, additional

Published
2017
Full Text
View/download PDF

116. Pulmonary metastasectomy for colorectal cancer: analysis of prognostic factors affecting survival

Author

Ampollini, Luca, primary, Gnetti, Letizia, additional, Goldoni, Matteo, additional, Viani, Lorenzo, additional, Faedda, Elisabetta, additional, Campanini, Nicoletta, additional, Caruana, Pietro, additional, Crafa, Pellegrino, additional, Negri, Francesca, additional, Pucci, Francesca, additional, Leonardi, Francesco, additional, Ventura, Luigi, additional, Balestra, Valeria, additional, Braggio, Cesare, additional, Bocchialini, Giovanni, additional, Del Rio, Paolo, additional, Silini, Enrico Maria, additional, Carbognani, Paolo, additional, and Rusca, Michele, additional

Published
2017
Full Text
View/download PDF

118. P3.03-012 Tumor-Infiltrating Lymphocytes, PDL-1, BAP-1, VEGFR-2 and IGF-1R Expression in Malignant Pleural Mesothelioma

Author

Ampollini, Luca, primary, Gnetti, Letizia, additional, Goldoni, Matteo, additional, Campanini, Nicoletta, additional, Ventura, Luigi, additional, Braggio, Cesare, additional, Tiseo, Marcello, additional, Balestra, Valeria, additional, Carbognani, Paolo, additional, Mutti, Antonio, additional, Silini, Enrico Maria, additional, and Rusca, Michele, additional

Published
2017
Full Text
View/download PDF

120. Allergia da animali da laboratorio.

Author

Corradi, Massimo, Selis, Luisella, Pela, Giovanna, Mozzoni, Paola, Andreoli, Roberta, and Goldoni, Matteo

Subjects
LABORATORY animals, SKIN tests, SALIVA, URINE, ANTIGENS
Abstract

Copyright of Giornale Italiano di Medicina del Lavoro ed Ergonomia is the property of Giornale Italiano di Medicina del Lavoro ed Ergonomia Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2019

121. Non-A non-B aortic dissection: a systematic review and meta-analysis.

Author

Carino, Davide, Singh, Mrinal, Molardi, Alberto, Agostinelli, Andrea, Goldoni, Matteo, Pacini, Davide, and Nicolini, Francesco

Subjects
AORTIC dissection, META-analysis, OPERATIVE surgery, NATURAL history, QUANTITATIVE research, LONGITUDINAL method
Abstract

View large Download slide View large Download slide OBJECTIVES Non - A non-B aortic dissections are rare, and little is known about their natural history, indications for surgery and operative results. We aim to examine the literature to summarize what is known of the natural history of non-A non-B dissections and evaluate the outcomes of the therapeutic options available. METHODS An extensive literature search was performed using MEDLINE to find all published studies that report data on the natural history and outcomes of patients with non-A non-B aortic dissection. Data on patients treated with medical therapy were extracted to characterize the natural history. Primary end points included 30-day mortality, stroke and retrograde type A dissection. RESULTS Of the 423 studies found, 14 articles (433 patients) fulfilled the inclusion criteria for quantitative analysis. The proportion of medically treated patients ranged from 5 to 54% with a pooled rate of 36% (50/138). The 30-day mortality of patients treated with medical therapy was 14% (7/50). The overall estimated proportion of 30-day mortality for patients who underwent intervention was 3.6% [95% confidence interval (CI) 1.7–5.6%], retrograde type A dissection was 2.6% (95% CI 0.8–4.4%) and stroke was 2.8% (95% CI 1.0–4.5%). CONCLUSIONS Despite the likelihood of reporting and selection bias, patients with non-A non-B dissection often have a complicated course requiring some form of intervention. The 30-day mortality of patients treated with medical therapy seems higher than surgical or endovascular therapy. Ideally, further large prospective studies are necessary to confirm our suggestion that early intervention may be indicated in non-A non-B dissections. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

122. Quantification of epicardial fat with cardiac CT angiography and association with cardiovascular risk factors in symptomatic patients: from the ALTER-BIO (Alternative Cardiovascular Bio-Imaging markers) registry.

Author

Milanese, Gianluca, Silva, Mario, Bruno, Livia, Goldoni, Matteo, Benedetti, Giorgio, Rossi, Enrica, Ferrari, Caterina, La Grutta, Ludovico, Maffei, Erica, Toia, Patrizia, Forte, Ernesto, Bonadonna, Riccardo C., Sverzellati, Nicola, Cademartiri, Filippo, and Grutta, Ludovico La

Abstract

Purpose: We aimed to assess the association between features of epicardial adipose tissue and demographic, morphometric and clinical data, in a large population of symptomatic patients with clinical indication to cardiac computed tomography (CT) angiography.Methods: Epicardial fat volume (EFV) and adipose CT density of 1379 patients undergoing cardiac CT angiography (918 men, 66.6%; age range, 18-93 years; median age, 64 years) were semi-automatically quantified. Clinical variables were compared between diabetic and nondiabetic patients to assess potential differences in EFV and adipose CT density. Multiple regression models were calculated to find the clinical variables with a significant association with EFV and adipose CT density.Results: The median EFV in diabetic patients (112.87 mL) was higher compared with nondiabetic patients (82.62 mL; P < 0.001). The explanatory model of the multivariable analysis showed the strongest associations between EFV and BMI (β=0.442) and age (β=0.365). Significant yet minor association was found with sex (β=0.203), arterial hypertension (β=0.072), active smoking (β=0.068), diabetes (β=0.068), hypercholesterolemia (β=0.046) and cardiac height (β=0.118). The mean density of epicardial adipose tissue was associated with BMI (β=0.384), age (β=0.105), smoking (β=0.088), and diabetes (β=0.085).Conclusion: In a large population of symptomatic patients, EFV is higher in diabetic patients compared with nondiabetic patients. Clinical variables are associated with quantitative features of epicardial fat. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

123. Left ventricular structure and remodeling in patients with COPD

Author

Pelà ,Giovanna, Li Calzi,Mauro, Pinelli,Silvana, Andreoli,Roberta, Sverzellati,Nicola, Bertorelli,Giuseppina, Goldoni,Matteo, Chetta,Alfredo Antonio, Pelà ,Giovanna, Li Calzi,Mauro, Pinelli,Silvana, Andreoli,Roberta, Sverzellati,Nicola, Bertorelli,Giuseppina, Goldoni,Matteo, and Chetta,Alfredo Antonio

Abstract

Giovanna Pelà,1 Mauro Li Calzi,1 Silvana Pinelli,1 Roberta Andreoli,1 Nicola Sverzellati,2 Giuseppina Bertorelli,1 Matteo Goldoni,1 Alfredo Chetta11Department of Clinical and Experimental Medicine, 2Department of Surgery, University Medical School, University Hospital Parma, Parma, ItalyBackground: Data on cardiac alterations such as left ventricular (LV) hypertrophy, diastolic dysfunction, and lower stroke volume in patients with COPD are discordant. In this study, we investigated whether early structural and functional cardiac changes occur in patients with COPD devoid of manifest cardiovascular disease, and we assessed their associations with clinical and functional features.Methods: Forty-nine patients with COPD belonging to all Global Initiative for Chronic Obstructive Lung Disease (GOLD) classes were enrolled and compared with 36 controls. All subjects underwent clinical history assessment, lung function testing, blood pressure measurement, electrocardiography, and conventional and Doppler tissue echocardiography. Patients were also subjected to computed tomography to quantify emphysema score.Results: Patients with COPD had lower LV cavity associated with a marked increase in relative wall thickness (RWT), suggesting concentric remodeling without significant changes in LV mass. RWT was significantly associated with ratio of the forced expiratory volume in 1 second to the forced vital capacity and emphysema score and was the only cardiac parameter that – after multivariate analysis – significantly correlated with COPD conditions in all individuals. Receiver operating characteristic curve analysis showed that RWT (with a cutoff point of 0.42) predicted the severity of COPD with 83% specificity and 56% sensitivity (area under the curve =0.69, 95% confidence interval =0.59–0.81). Patients with COPD showed right ventricular to be functional but no structural changes.Conclusion: Patients with COPD without evident car

Published
2016

125. Neutrophil Activation Promotes Fibrinogen Oxidation and Thrombus Formation in Behçet Disease

Author

Becatti, Matteo, primary, Emmi, Giacomo, additional, Silvestri, Elena, additional, Bruschi, Giulia, additional, Ciucciarelli, Lucia, additional, Squatrito, Danilo, additional, Vaglio, Augusto, additional, Taddei, Niccolò, additional, Abbate, Rosanna, additional, Emmi, Lorenzo, additional, Goldoni, Matteo, additional, Fiorillo, Claudia, additional, and Prisco, Domenico, additional

Published
2016
Full Text
View/download PDF

128. Bone marrow Dikkopf‐1 levels are a new independent risk factor for progression in patients with smouldering myeloma.

Author

Dalla Palma, Benedetta, Marchica, Valentina, Pedrazzoni, Mario, Accardi, Fabrizio, Notarfranchi, Laura, Goldoni, Matteo, De Luca, Federica, Costa, Federica, Storti, Paola, Toscani, Denise, Sammarelli, Gabriella, Bonomini, Sabrina, Aversa, Franco, and Giuliani, Nicola

Subjects
MULTIPLE myeloma, CYTOKINES, BONE marrow, CHEMOKINES, CANCER invasiveness, ENZYME-linked immunosorbent assay
Abstract

The article presents a study which examined the possible role played by bone marrow (BM) levels of such cytokines and chemokines as Activin A, C-C motif chemokine ligand 20 (CCL20), and Dickkopf 1 (DKK-1) in the progression of smouldering multiple myeloma (MM) in patients. Topics include the role of DKK-1 in tumoural progression via the increase in the number of myeloid-derived suppressor cells (MDSC) and the use of enzyme-linked immunosorbent assay (ELISA) kits in BM plasma analysis.

Published
2018
Full Text
View/download PDF

130. Sampling and analyzing alveolar exhaled breath condensate in mechanically ventilated patients: a feasibility study

Author

Vaschetto, Rosanna, primary, Corradi, Massimo, additional, Goldoni, Matteo, additional, Cancelliere, Laura, additional, Pulvirenti, Simone, additional, Fazzini, Ugo, additional, Capuzzi, Fabio, additional, Longhini, Federico, additional, Mutti, Antonio, additional, Corte, Francesco Della, additional, and Navalesi, Paolo, additional

Published
2015
Full Text
View/download PDF

133. Efficacy and safety profile of anti-interleukin-1 treatment in Behçet’s disease: a multicenter retrospective study

Author

Emmi, Giacomo, primary, Talarico, Rosaria, additional, Lopalco, Giuseppe, additional, Cimaz, Rolando, additional, Cantini, Fabrizio, additional, Viapiana, Ombretta, additional, Olivieri, Ignazio, additional, Goldoni, Matteo, additional, Vitale, Antonio, additional, Silvestri, Elena, additional, Prisco, Domenico, additional, Lapadula, Giovanni, additional, Galeazzi, Mauro, additional, Iannone, Florenzo, additional, and Cantarini, Luca, additional

Published
2015
Full Text
View/download PDF

134. Effects of TiO2 and Co3O4 Nanoparticles on Circulating Angiogenic Cells

Author

Spigoni, Valentina, primary, Cito, Monia, additional, Alinovi, Rossella, additional, Pinelli, Silvana, additional, Passeri, Giovanni, additional, Zavaroni, Ivana, additional, Goldoni, Matteo, additional, Campanini, Marco, additional, Aliatis, Irene, additional, Mutti, Antonio, additional, Bonadonna, Riccardo C., additional, and Dei Cas, Alessandra, additional

Published
2015
Full Text
View/download PDF

137. Non-invasive assessment of target dose and effects of pneumotoxic metals

Author

Goldoni, Matteo

Subjects
Chromium, Biomarkers of exposure and effect, Lead, Target dose, Nickel, MED/44, Exhaled breath condensate, Biomonitoring, Cadmium
Abstract

La raccolta e l’analisi del condensato dell’aria espirata (CAE) rappresentano al giorno d’oggi un approccio promettente per lo sviluppo di biomarcatori di esposizione ed effetto di elementi metallici pneumotossici inalati, poiché sono in grado di fornire informazioni complementari al monitoraggio biologico tradizionale effettuato nel sangue e nell’urina. In questo studio, il CAE è stato usato per caratterizzare l’esposizione a Cromo esavalente [Cr(VI)]. Il Cr nel CAE è stato validato come biomarcatore di esposizione, poiché correlava sia con le concetrazioni di Cr ambientali che con biomarcatori di stress ossidativo, come il perossido d’idrogeno e la malondialdeide, misurati nel CAE. Lo sviluppo di un metodo per monitorare Cr(VI) direttamente nel CAE e la sua cinetica di riduzione hanno mostrato una certa variabilità inter-individuale nel potenziale del lining fluid bronco-alveolare di catturare e ridurre elementi pneumotossici inalati a diversi stati di ossidazione. Sono riportati anche alcuni dati sull’esposizione a Nichel ed altri elementi pneumotossici derivanti dal fumo di sigaretta e da ambienti inquinati sono stati misurati nel CAE di soggetti di controllo, asmatici e con bronco-pneumopatia ostruttiva cronica. Collection and analysis of exhaled breath condensate (EBC) represent today a promising approach to develop biomarkers of exposure and effect of inhaled pneumotoxic metallic elements, thus providing complementary information to traditional biomonitoring performed in blood and urine. In this study, EBC was used to characterize exposure to hexavalent Chromium [Cr(VI)]. Chromium in EBC was validated as biomarker of exposure, owing to its correlation both with air concentrations and EBC biomarkers of oxidative stress, i.e., hydrogen peroxide and malondihaldeyde. The development of a method to monitor Cr(VI) in EBC and its reduction kinetics allowed the demonstration of some inter-individual variability in scavenging and reduction potential of broncho-alveolar lining fluid after inhalation of pneumotoxic elements at different oxidation states. Some data are also reported about exposure to nickel and other pneumotoxic elements contained in either tobacco smoke or polluted environments and measured in EBC from controls, asthmatics and patients with chronic obstructive pulmonary disease.

Published
2008

138. Titanium dioxide nanoparticles promote arrhythmias via a direct interaction with rat cardiac tissue

Author

Savi, Monia, primary, Rossi, Stefano, additional, Bocchi, Leonardo, additional, Gennaccaro, Laura, additional, Cacciani, Francesca, additional, Perotti, Alessio, additional, Amidani, Davide, additional, Alinovi, Rossella, additional, Goldoni, Matteo, additional, Aliatis, Irene, additional, Lottici, Pier Paolo, additional, Bersani, Danilo, additional, Campanini, Marco, additional, Pinelli, Silvana, additional, Petyx, Marta, additional, Frati, Caterina, additional, Gervasi, Andrea, additional, Urbanek, Konrad, additional, Quaini, Federico, additional, Buschini, Annamaria, additional, Stilli, Donatella, additional, Rivetti, Claudio, additional, Macchi, Emilio, additional, Mutti, Antonio, additional, Miragoli, Michele, additional, and Zaniboni, Massimiliano, additional

Published
2014
Full Text
View/download PDF

139. Persistent lone atrial fibrillation: Clinicopathologic study of 19 cases

Author

Corradi, Domenico, primary, Callegari, Sergio, additional, Manotti, Laura, additional, Ferrara, David, additional, Goldoni, Matteo, additional, Alinovi, Rossella, additional, Pinelli, Silvana, additional, Mozzoni, Paola, additional, Andreoli, Roberta, additional, Asimaki, Angeliki, additional, Pozzoli, Alberto, additional, Becchi, Gabriella, additional, Mutti, Antonio, additional, Benussi, Stefano, additional, Saffitz, Jeffrey E., additional, and Alfieri, Ottavio, additional

Published
2014
Full Text
View/download PDF

141. N-3 PUFA increase bioavailability and function of endothelial progenitor cells

Author

Spigoni, Valentina, primary, Lombardi, Carlo, additional, Cito, Monia, additional, Picconi, Angela, additional, Ridolfi, Valentina, additional, Andreoli, Roberta, additional, Anelli, Nadia, additional, Gnudi, Luigi, additional, Goldoni, Matteo, additional, Zavaroni, Ivana, additional, Raddino, Riccardo, additional, and Cas, Alessandra Dei, additional

Published
2014
Full Text
View/download PDF

146. Concentration of exhaled breath condensate biomarkers after fractionated collection based on exhaled CO 2 signal

Author

Goldoni, Matteo, primary, Corradi, Massimo, additional, Mozzoni, Paola, additional, Folesani, Giuseppina, additional, Alinovi, Rossella, additional, Pinelli, Silvana, additional, Andreoli, Roberta, additional, Pigini, Daniela, additional, Tillo, Raffaella, additional, Filetti, Angela, additional, Garavelli, Claudia, additional, and Mutti, Antonio, additional

Published
2013
Full Text
View/download PDF

148. Esposizione a nanoparticelle: studi in-vitro ed in-vivo per valutare i fattori di rischio cardiovascolari in cuori normali e patologici.

Author

Miragoli, Michele, Rossi, Stefano, Savi, Monia, Goldoni, Matteo, Pinelli, Silvana, Alinovi, Rossella, Galetti, Maricla, Stilli, Donatella, Macchi, Emilio, Zaniboni, Massimiliano, and Mutti, Antonio

Abstract

Copyright of Giornale Italiano di Medicina del Lavoro ed Ergonomia is the property of Giornale Italiano di Medicina del Lavoro ed Ergonomia Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2016

150. Efficacy and safety profile of anti-interleukin-1 treatment in Behçet's disease: a multicenter retrospective study.

Author

Emmi, Giacomo, Talarico, Rosaria, Lopalco, Giuseppe, Cimaz, Rolando, Cantini, Fabrizio, Viapiana, Ombretta, Olivieri, Ignazio, Goldoni, Matteo, Vitale, Antonio, Silvestri, Elena, Prisco, Domenico, Lapadula, Giovanni, Galeazzi, Mauro, Iannone, Florenzo, and Cantarini, Luca

Subjects
INTERLEUKIN-1, DRUG efficacy, MEDICATION safety, BEHCET'S disease, RETROSPECTIVE studies, DISEASE remission, PATIENTS, THERAPEUTICS
Abstract

Growing data have provided encouraging results on the use of interleukin (IL)-1 inhibitors in Behçet's disease (BD). This study was aimed at reporting the largest experience with anti-IL-1 agents in BD patients. We evaluated 30 BD patients receiving treatment with anti-IL-1 agents. The primary aims of the study were to evaluate the efficacy of anakinra (ANA) and canakinumab (CAN) in a cohort of BD. The secondary aims were to evaluate the overall safety profile of the treatments, explore the timing of response to therapy and any adjustment of dosage and frequency of drugs studied, and investigate predictive factors of response to therapy. The frequency of first line therapy was 90 % with ANA and 10 % with CAN. The overall number of subjects in complete remission after 12 months of therapy with anti-IL-1 drugs was 13: 6 maintained the initial therapy regimen, 1 maintained the same initial anti-IL-1 drug with further therapeutic adjustments, and the remaining 6 shifted from ANA to CAN. Among them, 3 used CAN for at least 12 months without therapeutic adjustments, 1 had therapeutic adjustments, and 3 had an overall history of a 12-month complete remission. Adverse events (AEs) were reported in 15 % patients who received ANA, represented in all cases by local cutaneous reactions, while no AE were observed in patients who received CAN; we did not observe any serious AEs (SAEs) during the follow-up period. Our data have confirmed that the use of anti-IL-1β drugs is efficacious and safe with an overall acceptable retention on treatment. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results