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491 results on '"Ji, ZhiYong"'

104. Novel bi-allelic variants in KASH5 are associated with meiotic arrest and non-obstructive azoospermia

Author

Yang, Chao, primary, Lin, Xiaoqi, additional, Ji, Zhiyong, additional, Huang, Yuhua, additional, Zhang, Ling, additional, Luo, Jiaqiang, additional, Chen, Huixing, additional, Li, Peng, additional, Tian, Ruhui, additional, Zhi, Erlei, additional, Hong, Yan, additional, Zhou, Zhi, additional, Zhang, Feng, additional, Li, Zheng, additional, and Yao, Chencheng, additional

Published
2022
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106. Additional file 1 of Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia

Author

Huang, Yuhua, Tian, Ruhui, Xu, Junwei, Ji, Zhiyong, Zhang, Yuxiang, Zhao, Liangyu, Yang, Chao, Li, Peng, Zhi, Erlei, Bai, Haowei, Han, Sha, Luo, Jiaqiang, Zhao, Jingpeng, Zhang, Jing, Zhou, Zhi, Li, Zheng, and Yao, Chencheng

Abstract

Additional file 1. CNV analysis using WES data and observation of wild- and mutated-type SYCE1 expression in vitro. (A–C) CNV analysis in the NOA-affected patient (P6326) (A) and his parents (B–C) using WES data; (D) WB assay detected the expression and size of mutant SYCE1 protein. The protein molecular weight represents the fusion expression of SYCE1 and Flag. NC indicated the negative control.

Published
2022
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110. Preliminary experience with 3D digital image microscope system on the treatment of varicocele

Author

Yao, Chencheng, primary, Xu, Wang, additional, Liu, Nachuan, additional, Zhi, Erlei, additional, Shi, Chenkun, additional, Ji, Zhiyong, additional, Zhao, Jingpeng, additional, Tian, Ruhui, additional, Huang, Yuhua, additional, Zhao, Fujun, additional, Chen, Huirong, additional, Zhang, Pei, additional, Pu, Ying, additional, Dong, Jianjun, additional, Li, Zheng, additional, and Li, Peng, additional

Published
2022
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111. Bi‐allelicSPATA22variants cause premature ovarian insufficiency and nonobstructive azoospermia due to meiotic arrest

Author

Yao, Chencheng, primary, Hou, Dong, additional, Ji, Zhiyong, additional, Pang, Dongmei, additional, Li, Peng, additional, Tian, Ruhui, additional, Zhang, Yuxiang, additional, Ou, Ningjing, additional, Bai, Haowei, additional, Zhi, Erlei, additional, Huang, Yuhua, additional, Qin, Yingying, additional, Zhao, Jingpeng, additional, Wang, Chenchen, additional, Zhou, Zhi, additional, Guo, Ting, additional, and Li, Zheng, additional

Published
2022
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120. Novel Bi-Allelic Variants of FANCM Cause Sertoli Cell-Only Syndrome and Non-Obstructive Azoospermia

Author

Zhang, Yuxiang, primary, Li, Peng, additional, Liu, Nachuan, additional, Jing, Tao, additional, Ji, Zhiyong, additional, Yang, Chao, additional, Zhao, Liangyu, additional, Tian, Ruhui, additional, Chen, Huixing, additional, Huang, Yuhua, additional, Zhi, Erlei, additional, Ou, Ningjing, additional, Bai, Haowei, additional, Zhou, Yuchuan, additional, Li, Zheng, additional, and Yao, Chencheng, additional

Published
2021
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124. Vitrification with microinjection of single seminiferous tubules: an efficient cryopreservation approach for limited testicular tissue

Author

Han, Sha, primary, Zhao, Liangyu, additional, Yang, Chao, additional, Xu, Junwei, additional, Yao, Chencheng, additional, Huang, Chuan, additional, Zhang, Hongbin, additional, Ji, Zhiyong, additional, Luo, Jiaqiang, additional, Guo, Yingying, additional, Hong, Yan, additional, Liu, Feng, additional, Zhou, Xinli, additional, Zhou, Zhi, additional, Huang, Yonghua, additional, and Li, Zheng, additional

Published
2021
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128. RNA‐binding protein ELAVL2 plays post‐transcriptional roles in the regulation of spermatogonia proliferation and apoptosis

Author

Yang, Chao, primary, Yao, Chencheng, additional, Ji, Zhiyong, additional, Zhao, Liangyu, additional, Chen, Huixing, additional, Li, Peng, additional, Tian, Ruhui, additional, Zhi, Erlei, additional, Huang, Yuhua, additional, Han, Xia, additional, Hong, Yan, additional, Zhou, Zhi, additional, and Li, Zheng, additional

Published
2021
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132. Bi-allelic MEI1variants cause meiosis arrest and non-obstructive azoospermia

Author

Zhang, Yuxiang, Li, Na, Ji, Zhiyong, Bai, Haowei, Ou, Ningjing, Tian, Ruhui, Li, Peng, Zhi, Erlei, Huang, Yuhua, Zhao, Jingpeng, Han, Yaqin, Zhang, Jing, Zhou, Yuchuan, Li, Zheng, and Yao, Chencheng

Abstract

Non-obstructive azoospermia (NOA) is characterized by the failure of sperm production due to testicular disorders and represents the most severe form of male infertility. Growing evidences have indicated that gene defects could be the potential cause of NOA via genome-wide sequencing approaches. Here, bi-allelic deleterious variants in meiosis inhibitor protein 1 (MEI1) were identified by whole-exome sequencing in four Chinese patients with NOA. Testicular pathologic analysis and immunohistochemical staining revealed that spermatogenesis is arrested at spermatocyte stage, with defective programmed DNA double-strand breaks (DSBs) homoeostasis and meiotic chromosome synapsis in patients carrying the variants. In addition, our results showed that one missense variant (c.G186C) reduced the expression of MEI1 and one frameshift variant (c.251delT) led to truncated proteins of MEI1 in in vitro. Furthermore, the missense variant (c.T1585A) was assumed to affect the interaction between MEI1 and its partners via bioinformatic analysis. Collectively, our findings provide direct genetic and functional evidences that bi-allelic variants in MEI1could cause defective DSBs homoeostasis and meiotic chromosome synapsis, which subsequently lead to meiosis arrest and male infertility. Thus, our study deepens our knowledge of the role of MEI1 in male fertility and provides a novel insight to understand the genetic aetiology of NOA.

Published
2023
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133. An Improved Authentication Protocol Using Smart Cards for the Internet of Things

Author

Liu Wanrong, He Xin, Cao Shouqi, Cao Liling, and Ji Zhiyong

Subjects
General Computer Science, Computer science, Internet of Things, 0211 other engineering and technologies, Context (language use), 02 engineering and technology, Computer security, computer.software_genre, privacy, Server, 0202 electrical engineering, electronic engineering, information engineering, General Materials Science, Protocol (object-oriented programming), Anonymous, Password, 021110 strategic, defence & security studies, Authentication, business.industry, General Engineering, 020206 networking & telecommunications, Authentication protocol, authentication, Timestamp, Smart card, lcsh:Electrical engineering. Electronics. Nuclear engineering, business, computer, lcsh:TK1-9971
Abstract

With the continuous development of IoT (Internet of Things) technology, IoT has become a typical representative of the development of new generation of information technology. The IoT allows people to use our data and computing resource anytime and everywhere. In the context of the IoT, the security of the vast amount of data generated by smart devices is one of the biggest concerns. To meet the challenge, the user authentication scheme in IoT should ensure the essential security performance protection and low computing costs. A authentication protocol preserving user anonymity was proposed by Nikooghadam et al. in 2017. In this paper, we further analyze the security of Nikooghadam et al.’s protocol and propose an improved anonymous authentication protocol for IoT. We use the timestamp mechanism and rely on CDH (Computational Diffie-Hellman) problem to improve security primarily. The security of the proposed protocol is verified using BAN logic and the performance comparison and efficiency analysis are carried out. The results show that our improved protocol has higher security with little more computation cost.

Published
2019

136. A High-Efficiency Energy Harvesting by Using Hydraulic Electromagnetic Regenerative Shock Absorber

Author

Guoxing Li, Ji Zhiyong, Zhifei Wu, Muhammad Yousaf Iqbal, Hu GuiCheng, and Wang Tie

Subjects
Vibration, Energy recovery, Shock absorber, Materials science, Regenerative shock absorber, Energy transformation, Mechanical engineering, Dissipation, Energy harvesting, Mechanical energy
Abstract

This article intends a hybrid energy-harvesting shock absorber design which comprehends energy harvesting of automobile suspension vibration dissipation. A mathematical model of the energy harvesting prototype is established, and simulation results show that the dissipation energy can be recovered by varying the feed module, thereby got the damping forces (DF) ratio at different compression and extension stroke. The energy conversion from hydraulic energy to mechanical energy mainly then mechanical energy converted into electrical energy furthermore, we can recharge our battery from this recovered energy. This advanced mathematical model and prototype proposed maximum ride comfort meanwhile recovered the maximum suspension energy and fuel saving. This article shows the simulation results verifying it with prototype test results. The DF of expansion stroke is higher than the DF of compression stroke. The damping characteristics curves and speed characteristics curves verify the validity by simulation and prototyping damper at different amplitudes of off-road vehicles. The Hydraulic Electromagnetic Regenerative Shock Absorber (HERSA) prototype characteristic is tested in which 65 watts recovered energy at 1.67 Hz excitation frequency. So, 14.65% maximum energy recovery efficiency got at 20 mm rod diameter and 8 cc/rev motor displacement. The damping characteristics of the HERSA prototype examined and it has ideal performance as the standard requirements of the National Standard QC/T 491-1999.

Published
2021

137. Study on the Structure of a Mixed KCl and K 2 SO 4 Aqueous Solution Using a Modified X-ray Scattering Device, Raman Spectroscopy, and Molecular Dynamics Simulation.

Author

Qiao, Mengdan, Li, Fei, Meng, Xianze, Wang, Meiling, Zhu, Hanyu, Ji, Zhiyong, Zhao, Yingying, Liu, Jie, Wang, Shizhao, Guo, Xiaofu, Bi, Jingtao, and Yuan, Junsheng

Subjects
MOLECULAR dynamics, RAMAN spectroscopy, X-ray scattering, AQUEOUS solutions, HYDROGEN bonding
Abstract

The microstructure of a mixed KCl and K2SO4 aqueous solution was studied using X-ray scattering (XRS), Raman spectroscopy, and molecular dynamics simulation (MD). Reduced structure functions [F(Q)], reduced pair distribution functions [G(r)], Raman spectrum, and pair distribution functions (PDF) were obtained. The XRS results show that the main peak (r = 2.81 Å) of G(r) shifted to the right of the axis (r = 3.15 Å) with increased KCl and decreased K2SO4. The main peak was at r = 3.15 Å when the KCl concentration was 26.00% and the K2SO4 concentration was 0.00%. It is speculated that this phenomenon was caused by the main interaction changing, from K-OW (r = 2.80 Å) and OW-OW (r = 2.80 Å), to Cl−-OW (r = 3.14 Å) and K+-Cl− (r = 3.15 Å). According to the trend of the hydrogen bond structure in the Raman spectrum, when the concentration of KCl was high and K2SO4 was low, the destruction of the tetrahedral hydrogen bond network in the solution was more serious. This shows that the destruction strength of the anion to the hydrogen bond network structure in solution was Cl− > SO42−. In the MD simulations, the coordination number of OW-OW decreased with increasing KCl concentration, indicating that the tetrahedral hydrogen bond network was severely disrupted, which confirmed the results of the Raman spectroscopy. The hydration radius and coordination number of SO42− in the mixed solution were larger than Cl−, thus revealing the reason why the solubility of KCl in water was greater than that of K2SO4 at room temperature. [ABSTRACT FROM AUTHOR]

Published
2022
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