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102 results on '"Jingchao Liu"'

102. Gadofullerene inhibits the degradation of apolipoprotein B100 and boosts triglyceride transport for reversing hepatic steatosi.

Author

Chen Zhou, Mingming Zhen, Meilan Yu, Xue Li, Tong Yu, Jingchao Liu, Wang Jia, Shuai Liu, Lei Li, Jie Li, Zihao Sun, Zhongpu Zhao, Xinyao Wang, Xiaoyan Zhang, Chunru Wang, and Chunli Bai

Subjects
*NADH dehydrogenase, *ACETYLCOENZYME A, *MEDICAL sciences, *SCIENTIFIC apparatus & instruments, *FATTY liver, *LIPID transfer protein
Abstract

The article explore a promising anti-hepatic steatosis strategy by boosting hepatocellular triglyceride (TG) transport using b-alanine–modified gadofullerene (GF-Ala) nanoparticles. It mentions that GF-Ala could reverse hepatic steatosis in oleic acid–induced hepatocytes, fructose-induced mice. It also mentions that GF-Ala could potently ameliorate hepatic TG transport and maintain hepatic metabolic homeostasis without apparent toxicity.

Published
2020
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