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541 results on '"Jung, Yong Hun"'

109. Comparison of effects of desflurane and sevoflurane on postoperative nausea, vomiting, and pain in patients receiving opioid-based intravenous patient-controlled analgesia after thyroidectomy

Author

Yoon, Il Jae, Kang, Hyun, Baek, Chong Wha, Choi, Geun Joo, Park, Yong-Hee, Jung, Yong Hun, Woo, Young Cheol, and Lee, Sangseok

Subjects
Adult, Male, Methyl Ethers, Pain, Postoperative, Isoflurane, sevoflurane, Observational Study, postoperative nausea and vomiting, Analgesia, Patient-Controlled, Middle Aged, Analgesics, Opioid, desflurane, thyroidectomy, Anesthetics, Inhalation, Humans, Female, opioid-based patient control analgesics, Propensity Score, Research Article
Abstract

In this study, we aimed to compare the effect of desflurane and sevoflurane on postoperative nausea and vomiting and pain in patients receiving opioid-based intravenous patient-controlled analgesia (IV-PCA) after thyroidectomy. We reviewed the electronic medical records of 1042 patients administered opioid-based IV-PCA after a thyroidectomy at Chung-Ang University Hospital between January 1, 2010 and June 30, 2016. We classified the patients into 2 groups according to the inhalation anesthetic used for anesthesia: desflurane versus sevoflurane (groups D and S, n = 587 and 455, respectively). Then, propensity scoring was used to select 234 matched subjects between both groups based on their confounding factors. A propensity score matching method was used to match patients from the 2 groups in a 1:1 ratio. Before the propensity score analysis, there was no significant difference between the 2 groups. However, after the propensity score matching, the frequency of complete remission (CR, defined as no nausea and vomiting) was significantly higher in group S than it was in group D. The number of patients administered rescue antiemetics on day 0 in group S was lower than that in group D, although it was not statistically significant. In patients receiving opioid-based IV-PCA after thyroidectomy, sevoflurane seems to be more beneficial in achieving CR than desflurane was. However, further randomized controlled studies are needed to confirm this conclusion.

Published
2017

111. Pralidoxime administered during cardiopulmonary resuscitation facilitates successful resuscitation in a pig model of cardiac arrest.

Author

Jung, Yong Hun, Lee, Hyoung Youn, Jeung, Kyung Woon, Lee, Byung Kook, Youn, Chun Song, Yun, Seong Woo, Heo, Tag, and Min, Yong Il

Subjects
*CARDIOPULMONARY resuscitation, *CARDIAC arrest, *ANTIDOTES, *SPRAGUE Dawley rats, *SWINE, *RESUSCITATION, *ARTERIAL pressure, *CONTROL groups
Abstract

Pralidoxime is a common antidote for organophosphate poisoning; however, studies have also reported pralidoxime's pressor effect, which may facilitate the restoration of spontaneous circulation (ROSC) after cardiac arrest by improving coronary perfusion pressure (CPP). We investigated the immediate cardiovascular effects of pralidoxime in anaesthetised normal rats and the effects of pralidoxime administration during cardiopulmonary resuscitation (CPR) in a pig model of cardiac arrest. To evaluate the immediate cardiovascular effects of pralidoxime, seven anaesthetised normal rats received saline or pralidoxime (20 mg/kg) in a randomised crossover design, and the responses were determined using the conductance catheter technique. To evaluate the effects of pralidoxime administration during CPR, 22 pigs randomly received either 80 mg/kg of pralidoxime or an equivalent volume of saline during CPR. In the rats, pralidoxime significantly increased arterial pressure than saline (P =.044). The peak effect on arterial pressure was observed in the first minute. In a pig model of cardiac arrest, CPP during CPR was higher in the pralidoxime group than in the control group (P =.002). ROSC was attained in three animals (27.3%) in the control group and nine animals (81.8%) in the pralidoxime group (P =.010). Three animals (27.3%) in the control group and eight animals (72.2%) in the pralidoxime group survived the 6‐hour period (P =.033). In conclusion, pralidoxime had a rapid onset of pressor effect. Pralidoxime administered during CPR led to significantly higher rates of ROSC and 6‐hour survival by improving CPP in a pig model. [ABSTRACT FROM AUTHOR]

Published
2020
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117. Comparative Efficacy of the Air-Q Intubating Laryngeal Airway during General Anesthesia in Pediatric Patients: A Systematic Review and Meta-Analysis

Author

Ahn, Eun Jin, Choi, Geun Joo, Kang, Hyun, Baek, Chong Wha, Jung, Yong Hun, Woo, Young Cheol, and Bang, Si Ra

Subjects
Article Subject, respiratory system, respiratory tract diseases
Abstract

Air-Q® (air-Q) is a supraglottic airway device which can be used as a guidance of intubation in pediatric as well as in adult patients. We evaluated the efficacy and safety of air-Q compared to other airway devices during general anesthesia in pediatric patients by conducting a systematic review and meta-analysis. A total of 10 studies including 789 patients were included in the final analysis. Compared with other supraglottic airway devices, air-Q showed no evidence for a difference in leakage pressure and insertion time. The ease of insertion was significantly lower than other supraglottic airway devices. The success rate of intubation was significantly lower than other airway devices. However, fiberoptic view was better through the air-Q than other supraglottic airway devices. Therefore, air-Q could be a safe substitute for other airway devices and may provide better fiberoptic bronchoscopic view.

Published
2016
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127. Comparison of hemodynamic response to tracheal intubation and postoperative pain in patients undergoing closed reduction of nasal bone fracture under general anesthesia: a randomized controlled trial comparing fentanyl and oxycodone

Author

Lee, Yeon Sil, primary, Baek, Chong Wha, additional, Kim, Dong Rim, additional, Kang, Hyun, additional, Choi, Geun Joo, additional, Park, Yong-Hee, additional, Kim, Won-joong, additional, Jung, Yong Hun, additional, and Woo, Young Cheol, additional

Published
2016
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143. Multi-unit Level 3 probabilistic safety assessment: Approaches and their application to a six-unit nuclear power plant site

Author

Kim, Sung-yeop, Jung, Yong Hun, Han, Sang Hoon, Han, Seok-Jung, and Lim, Ho-Gon

Abstract

The importance of performing Level 3 probabilistic safety assessments (PSA) along with a general interest in assessing multi-unit risk has been sharply increasing after the Fukushima Daiichi nuclear power plant (NPP) accident. However, relatively few studies on multi-unit Level 3 PSA have been performed to date, reflecting limited scenarios of multi-unit accidents with higher priority. The major difficulty to carry out a multi-unit Level 3 PSA lies in the exponentially increasing number of multi-unit accident combinations, as different source terms can be released from each NPP unit; indeed, building consequence models for the astronomical number of accident scenarios is simply impractical. In this study, a new approach has been developed that employs the look-up table method to cover every multi-unit accident scenario. Consequence results for each scenario can be found on the table, established with a practical amount of effort, and can be matched to the frequency of the scenario. Preliminary application to a six-unit NPP site was carried out, where it was found that the difference between full-coverage and cut-off cases could be considerably high and therefore influence the total risk. Additional studies should be performed to fine tune the details and overcome the limitations of the approach.

Published
2018
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146. Effect of ultrasound-guided phrenic nerve block on shoulder pain after laparoscopic cholecystectomy-a prospective, randomized controlled trial.

Author

Yi, Myung, Kim, Won, Kim, Min, Kang, Hyun, Park, Yong-Hee, Jung, Yong, Lee, Seung, Shin, Hwa, Yi, Myung Sub, Kim, Won Joong, Kim, Min Kyoung, Jung, Yong Hun, Lee, Seung Eun, and Shin, Hwa Yong

Subjects
SHOULDER pain diagnosis, CHOLECYSTECTOMY complications, PHRENIC nerve, LAPAROSCOPIC surgery complications, NERVE block, DIAGNOSTIC ultrasonic imaging, PULMONARY function tests, POSTOPERATIVE pain prevention, AMIDES, CHOLECYSTECTOMY, COMPARATIVE studies, LAPAROSCOPIC surgery, LOCAL anesthetics, LONGITUDINAL method, RESEARCH methodology, MEDICAL cooperation, POSTOPERATIVE pain, RESEARCH, STATISTICAL sampling, SHOULDER pain, ULTRASONIC imaging, EVALUATION research, PAIN measurement, RANDOMIZED controlled trials, TREATMENT effectiveness, BLIND experiment, DIAGNOSIS, PREVENTION
Abstract

Background: Post-laparoscopic shoulder pain (PLSP) frequently follows a laparoscopic cholecystectomy. A proposed mechanism for PLSP is the irritation or injury of the phrenic nerve by the CO2 pneumoperitoneum during laparoscopic surgery. Here, we investigated whether a phrenic nerve block (PNB), performed under ultrasound guidance, could reduce the incidence and severity of PLSP after laparoscopic cholecystectomy.Method: Sixty patients were randomized into two groups, with one group receiving PNB with 4 ml (30 mg) of 0.75% ropivacaine (group P, n = 28) and a control group (group C, n = 32). The existence and severity of PLSP were assessed for 2 days postoperatively. A pulmonary function test (PFT) and diaphragmatic excursion test were performed pre- and postoperatively.Results: With ultrasound guidance, all PNBs were performed successfully in group P. In group P, the overall incidence and severity of PLSP decreased significantly. There were no significant differences in incisional pain, visceral pain, and analgesic requirements between the groups. Right-side diaphragmatic excursion decreased significantly in group P at 1 h postoperatively. The PFT results and respiratory discomfort assessed by a modified Borg's scale were not different significantly between the groups.Conclusion: Based on these findings, ultrasound-guided PNB can prevent or reduce the PLSP without clinically significant respiratory discomfort. [ABSTRACT FROM AUTHOR]

Published
2017
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147. Comparison of effects of desflurane and sevoflurane on postoperative nausea, vomiting, and pain in patients receiving opioid-based intravenous patient-controlled analgesia after thyroidectomy: Propensity score matching analysis.

Author

Il Jae Yoon, Hyun Kang, Chong Wha Baek, Geun Joo Choi, Yong-Hee Park, Yong Hun Jung, Young Cheol Woo, Sangseok Lee, Yoon, Il Jae, Kang, Hyun, Baek, Chong Wha, Choi, Geun Joo, Park, Yong-Hee, Jung, Yong Hun, Woo, Young Cheol, and Lee, Sangseok

Published
2017
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