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123 results on '"Khomyakov, V. A."'

101. Experience with hyperthermic intraoperative intraperitoneal chemotherapy in the treatment of locally advanced gastric cancer (Cyt+)

Author

Kaprin, A. D., primary, Sobolev, D. D., additional, Khomyakov, V. M., additional, Bolotina, L. V., additional, Ryabov, A. B., additional, Khoronenko, V. E., additional, Shemetova, M. M., additional, Kramskaya, L. V., additional, Kolobaev, I. V., additional, Ivanov, A. V., additional, and Utkina, A. B., additional

Published
2015
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104. Results of combined treatment using hyperthermic intraoperative intraperitoneal chemotherapy in patients with locally advanced and disseminated gastric cancer

Author

Kaprin, A. D., primary, Sobolev, D. D., additional, Khomyakov, V. M., additional, Bolotina, L. V., additional, Ryabov, A. B., additional, Khoronenko, V. E., additional, Kolobaev, I. V., additional, Shemetova, M. M., additional, Kramskaya, L. V., additional, and Ivanov, A. V., additional

Published
2014
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105. NEVOD-DECOR experiment: results and future

Author

Saavedra, O, primary, Amelchakov, M B, additional, Barbashina, N S, additional, Bogdanov, A G, additional, Chernov, D V, additional, Chiavassa, A, additional, Dushkin, L I, additional, Khokhlov, S S, additional, Khomyakov, V A, additional, Kindin, V V, additional, Kokoulin, R P, additional, Kompaniets, K G, additional, Mannocchi, G, additional, Yu Matveev, S, additional, Petrukhin, A A, additional, Shestakov, V V, additional, Shulzhenko, I A, additional, Shutenko, V V, additional, Trinchero, G, additional, Yashin, I I, additional, and Zadeba, E A, additional

Published
2013
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112. Cherenkov water calorimeter on the basis of quasispherical modules

Author

Kindin, V. V., Amelchakov, M. B., Barbashina, N. S., Bogdanov, A. G., Burtsev, V. D., Chernov, D. V., Khokhlov, S. S., Khomyakov, V. A., Kokoulin, R. P., Kompaniets, K. G., Kovylyaeva, E. A., Kruglikova, V. S., Ovchinnikov, V. V., Petrukhin, A. A., Shulzhenko, I. A., Shutenko, V. V., Yashin, I. I., and Egor Zadeba

114. Cascade showers initiated by muons in the Cherenkov water detector NEVOD

Author

Kokoulin, R. P., Amelchakov, M. B., Barbashina, N. S., Bogdanov, A. G., Burtsev, V. D., Chernov, D. V., Dushkin, L. I., Gromushkin, D. M., Kamlev, N. N., Khokhlov, S. S., Khomyakov, V. A., Kindin, V. V., Kompaniets, K. G., Kovylyaeva, E. A., Kruglikova, Vs, Mannocchi, G., Ovchinnikov, V. V., Petrukhin, A. A., Saavedra, O., Shulzhenko, I. A., Shutenko, V. V., Gian Carlo Trinchero, Yashin, I. I., and Zadeba, E. A.

118. Intraoperative photodynamic therapy in gastric cancer patients

Author

Elena Filonenko, Kaprin, A. D., Suleymanov, E. A., Urlova, A. N., Khomyakov, V. M., Vashakmadze, L. A., Sokolov, V. V., and Kirillov, N. V.

Subjects
0301 basic medicine, 030103 biophysics, medicine.medical_specialty, lcsh:Medical technology, Locally advanced, Dermatology, Palliative surgery, 03 medical and health sciences, Medical technology, medicine, In patient, R855-855.5, Chemical treatment, business.industry, gastric cancer, Cancer, peritoneal carcinomatosis, medicine.disease, Surgery, Cancer treatment, lcsh:R855-855.5, Gastric cancer stage, intraoperative photodynamic therapy, business, Median survival
Abstract

Results of intraoperative photodynamic therapy (IOPDT) in patients with gastric cancer are represented in the article. The study included 240 patients with gastric cancer stage II-IV (Т3-4N0-3M0-1) with evident or suspected peritoneal dissemination who underwent examination and treatment in P.Herzen Moscow Oncology Research Institute. The group 1, the study group, included 140 patients who underwent nominally curative or palliative surgery for locally advanced and disseminated gastric cancer with IOPDT as additional intraoperative intervention for antiblastics and cancer treatment. The group 2, the control group, included 100 patients who also underwent nominally curative or palliative surgery (equal to extent of surgery in patients from the study group) for locally advanced and disseminated gastric cancer and no intraoperative implication of physical or chemical treatment methods. IOPDT did not worsen a course of early post-operative period, did not impact on severity of post-operative complications and was not associated with increase of post-operative mortality. IOPDT allowed for improvement of 1-year and 3-year disease-specifi c survival rates: by 16.1% and 16.7%, respectively. For nominally curative resections, median survival, 1- year and 3-year disease-specifi c survival rates were improved by 14 months, 17.8% and 31.3%, respectively. For R1, R2 resections, IOPDT improved 1-year disease-specifi c survival rates by 16.4%. Additionally, for nominally curative resections IOPDT did not increase the recurrence rate and improved median recurrence-free survival, 1-year and 3-year recurrence-free survival rates by 16 months, 27.2% and 25.4%, respectively.

123. Neuroendocrine Carcinoma (NEC) and Composite Exocrine-Neuroendocrine Carcinoma (CENEC) of the Stomach: A Clinicopathological Review of 58 Cases.

Author

Vashakmodze, L., Belous, T., Khomyakov, V., Cheremissov, V., and Mutasov, A.

Subjects
NEUROENDOCRINE tumors, CARCINOID, STOMACH cancer, CANCER invasiveness, CANCER patients, SYNAPTOPHYSIN
Abstract

Introduction: NEC of the stomach is an uncommon tumor accounting for 0.5% of all gastric carcinomas and about 6% of gastric NETs. CENEC contain both areas of NEC and conventional carcinoma. The histological diagnosis is difficult. Aim(s): To evaluate clinicopathological features and prognosis of NEC. Materials and methods: The retrospective analysis of the pathologic reports from 1999 to 2011 has identified 58 cases of gastric NEC/CENEC. All samples have been newly examined by one pathologist using immunohistochemical (IHC) staining. CENECs with at least 30% of NE component were included. In total, 41 NEC and 17 CENEC were studied. Results: At the IHC, 88.8% of tumors were positive for synaptophysin; 64.1% for neuron-specific enolase; 42.6% for chromogranin A; 42.5% for CD-56. The majority of tumors (86%) had Ki-67>30% and one third had >70%. There were 40 male, 18 female, median age was 65 y.o. Twenty-seven of 58 tumors localized in the upper third of the stomach, esophageal involvement was found in 30%. Fifty-six pts were operated. Advanced disease was found in most cases - pT3/T4 tumors accounted for 69.7% of all cases and 75% was N-positive. Every fifth pt had distant metastases. Seventy-five percent of pts classified as pTNM stage III/IV. Median survival was 18 months for all stages and only seven for stage IV. Conclusion: NEC/CENEC are aggressive malignancies with high metastatic potential. The pathologic diagnosis is difficult and based on IHC staining. The survival of patients with advanced disease is poor after both surgical and nonsurgical treatment. [ABSTRACT FROM AUTHOR]

Published
2012

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