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438 results on '"Knott‐Craig, Christopher"'

103. 1168

Author

Kimura, Dai, primary, Figueroa, Mayte, additional, Knott-Craig, Christopher, additional, and Shah, Samir, additional

Published
2014
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118. Is the “Perfect Fontan” operation routinely achievable in the modern era?

Author

Kirklin, James K., primary, Brown, Robert N., additional, Bryant, Ayesha S., additional, Naftel, David C., additional, Colvin, Edward V., additional, Bennett Pearce, F., additional, Romp, Robb L., additional, Johnson, Walter H., additional, Lau, Yung R., additional, McMahon, William S., additional, Knott-Craig, Christopher J., additional, and Pacifico, Albert D., additional

Published
2008
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124. Acute Kidney Injury Following Cardiac Surgery in Neonates and Young Infants: Experience of a Single Center Using Novel Perioperative Strategies

Author

Kumar, T. K. Susheel, Allen, Jerry, CCP, Spentzas, Thomas, Berrios, Lindsay, CCP, Shah, Samir, Joshi, Vijaya M., Ballweg, Jean A., and Knott-Craig, Christopher J.

Abstract

Objective: Acute kidney injury (AKI) following cardiac surgery is a serious complication with a reported incidence of 30% to 50%. This study sought to determine the prevalence and risk factors for AKI among neonates and young infants undergoing repair of cardiac defects at an institution using novel perioperative strategies.Methods: A retrospective analysis of 102 consecutive infants (<2 months) undergoing repair of cardiac defects on cardiopulmonary bypass formed the study group. Cardiac diagnoses were stratified according to the Society of Thoracic Surgeons Congenital Heart Surgery (STAT) mortality categories. The prevalence of AKI within 72 hours was defined according to the three-stage Acute Kidney Injury Network criteria. Novel bypass strategies to preserve renal function included maintenance of higher hematocrit and high flow rates on cardiopulmonary bypass despite systemic hypothermia, and avoidance of albumin and milrinone in the perioperative period.Results: Mean age was 24 ± 19 days. Eighteen patients were less than 7 days of age at the time of surgery. Patient distribution according to STAT categories was as follows: 1 (n = 21), 2 (n = 12), 3 (n = 22), 4 (n = 28), and 5 (n = 19). The incidence of stages 1, 2, and 3 AKI in the population was 8% (n = 9), 2% (n = 2), and 0% (n = 0), respectively. On multivariate analysis higher STAT category was the only significant risk factor for AKI.Conclusion: Current incidence of AKI following cardiac surgery in young infants at our institution is low. Novel perioperative strategies may have contributed to the low observed incidence of AKI in our patient population. Increased complexity of heart disease was a risk factor for AKI.

Published
2016
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132. Vasopressin After the Fontan Operation

Author

Kumar, T. K. Susheel, Kashyap, Pooja, Figueroa, Mayte, Zurakowski, David, Allen, Jerry, Ballweg, Jean A., Sathanandam, Shyam, Ali, Mohammed, and Knott-Craig, Christopher J.

Abstract

Background: Prolonged pleural effusion following Fontan operation is common and increases morbidity and hospital length of stay. Vasopressin (VP), a neurohypophysial hormone, has numerous effects on the cardiovascular system. The most notable is increased peripheral vascular resistance, but it may also reduce capillary leakage by tightening endothelial intercellular junctions and reducing capillary hydrostatic pressure We reviewed our experience with the perioperative administration of VP following Fontan operation.Methods: We retrospectively reviewed the records of 62 consecutive patients who underwent Fontan operation from January 2004 to June 2014. In January 2010, VP was introduced as part of the standard perioperative management of patients undergoing Fontan operation at our center. For this retrospective observational study, patients were grouped according to the use (VP; N = 40) or nonuse (non-VP; N = 22) of VP (0.3-0.5 mU/kg/min) in the perioperative period. The primary end point analyzed was chest tube output. Secondary end points analyzed included fluid balance and length of hospital stay, with groups compared using Mann-Whitney Utest.Results: There was no hospital mortality. Median total chest tube output was 22 mL/kg in the VP group and 68 mL/kg in the non-VP group (P< .001). The median total duration of chest tube indwelling time was five days in the VP group and was 11 days in the non-VP group (P< .001). Median fluid balance on first postoperative day was 13 and 38 mL/kg, respectively (P< .001). Median hospital stay for VP and non-VP groups was 9 and 16 days, respectively (P= .002).Conclusions: The more recent group of patients undergoing Fontan operations, all of whom received VP perioperatively, had less chest tube output and shorter duration of chest tube drainage after the Fontan operation relative to the earlier patient group whose perioperative management did not include VP. They also experienced less positive fluid balance in the early postoperative period and shorter hospital length of stay than the patients from the earlier era.

Published
2016
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148. Pulmonary Autograft Replacement in Children The Ideal Solution?

Author

ELKINS, RONALD C., primary, SANTANGELO, KATHYLEE, additional, RANDOLPH, JOHN D., additional, KNOTT-CRAIG, CHRISTOPHER J., additional, STELZER, PAUL, additional, THOMPSON, WEBB M., additional, RAZOOK, JERRY D., additional, WARD, KENT E., additional, and OVERHOLT, EDWARD D., additional

Published
1992
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150. Carcinoid disease of the heart

Author

Knott-Craig, Christopher J., primary, Schaff, Hartzell V., additional, Mullany, Charles J., additional, Kvols, Larry K., additional, Moertel, Charles G., additional, Edwards, William D., additional, and Danielson, Gordon K., additional

Published
1992
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