101. An electrochemiluminescence aptasensor based on Ti3C2 QDs-1T/2H MoS2 nano-hybrid material for the highly sensitive detection of lincomycin.
- Author
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Du, Lin, Zhang, Huixin, Zhang, Feifei, Xia, Jianfei, Meng, Qingyang, Huang, Hongjie, and Wang, Zonghua
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ELECTROCHEMILUMINESCENCE , *LINCOMYCIN , *FOOD chemistry , *FOOD safety , *DETECTION limit , *CHEMILUMINESCENCE - Abstract
Developing a highly selective and sensitive analysis strategy for lincomycin (LIN) is of great significance for environmental protection and food safety. Herein, we reported a novel electrochemiluminescence (ECL) aptasensor based on Ti 3 C 2 QDs-1T/2H MoS 2 nano-hybrid luminophore for detection of LIN. The hybridization of Ti 3 C 2 QDs and 1T/2H MoS 2 endowed nanocomposite with structural and compositional advantages for boosting the ECL performance of QDs by about three times. This enhancement could be attributed to the remarkable electrocatalytic activity and high conductivity exhibited by 1T/2H MoS 2. Secondly, the great surface area of 1T/2H MoS 2 is conducive to the high dispersion of Ti 3 C 2 QDs, and its good conductivity could promote charge transfer. On the other hand, the excellent catalytic performance of 1T/2H MoS 2 could facilitate the reduction of S 2 O 8 2− to produce more radical, which significantly enhance the ECL signal of Ti 3 C 2 QDs. Given these features, a sensor for detection of LIN was established based on specific recognition between target and aptamer. The sensor showed a good linear relationship (0.05 ng mL−1 ∼100 μg mL−1) with a detection limit as low as 0.02 ng mL−1. It is worth noting that this work has been validated in testing milk samples, exhibiting great potential application prospects in food analysis. [Display omitted] • A new ECL aptasensor for analyzing LIN was developed based on Ti 3 C 2 QDs-1T/2H MoS 2. • 1T/2H MoS 2 as a carrier and catalysis can improve the ECL performance of Ti 3 C 2 QDs. • The LIN aptasensor displayed excellent selectivity and high sensitivity. • The ECL sensor was used to detect LIN in milk samples with satisfactory results. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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