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104. Corrigendum: Human umbilical cord mesenchymal stem cell-derived exosomes promote murine skin wound healing by neutrophil and macrophage modulations revealed by single-cell RNA sequencing

Author

Liu, Yuanyuan, primary, Zhang, Mingwang, additional, Liao, Yong, additional, Chen, Hongbo, additional, Su, Dandan, additional, Tao, Yuandong, additional, Li, Jiangbo, additional, Luo, Kai, additional, Wu, Lihua, additional, Zhang, Xingyue, additional, and Yang, Rongya, additional

Published
2023
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105. Human umbilical cord mesenchymal stem cell-derived exosomes promote murine skin wound healing by neutrophil and macrophage modulations revealed by single-cell RNA sequencing

Author

Liu, Yuanyuan, primary, Zhang, Mingwang, additional, Liao, Yong, additional, Chen, Hongbo, additional, Su, Dandan, additional, Tao, Yuandong, additional, Li, Jiangbo, additional, Luo, Kai, additional, Wu, Lihua, additional, Zhang, Xingyue, additional, and Yang, Rongya, additional

Published
2023
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124. Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma

Author

Fu, Liangmin, primary, Bao, Jiahao, additional, Li, Jinhui, additional, Li, Qiuyang, additional, Lin, Hansen, additional, Zhou, Yayun, additional, Li, Jiangbo, additional, Yan, Yixuan, additional, Langston, Marvin E., additional, Sun, Tianhao, additional, Guo, Songliang, additional, Zhou, Xinwei, additional, Chen, Yuhang, additional, Liu, Yujun, additional, Zhao, Yiqi, additional, Lu, Jun, additional, Huang, Yong, additional, Chen, Wei, additional, Chung, Benjamin I., additional, and Luo, Junhang, additional

Published
2022
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132. Challenges in Implementing an ESP Service

Author

Calvert, Kenneth L., Griffioen, James, Imam, Najati, Li, Jiangbo, Goos, Gerhard, Series editor, Hartmanis, Juris, Series editor, van Leeuwen, Jan, Series editor, Wakamiya, Naoki, editor, Solarski, Marcin, editor, and Sterbenz, James, editor

Published
2004
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134. Knockdown of LMNB1 Inhibits the Proliferation of Lung Adenocarcinoma Cells by Inducing DNA Damage and Cell Senescence

Author

Li, Jiangbo, Sun, Zhijia, Cui, Yingshu, Qin, Lingmei, Wu, Fengyun, Li, Yufang, Du, Nan, and Li, Xiaosong

Subjects
Cancer Research, Oncology
Abstract

BackgroundLung cancer has considerably high mortality and morbidity rate. Lung adenocarcinoma (LUAD) tissues highly express lamin B1 (LMNB1), compared with normal tissues. In this study, we knocked down LMNB1 in LUAD cells A549 and NCI-1299 to explore the effect of its inhibition on the proliferation of cells and the potential mechanism.MethodsUsing bioinformatics methods, we analyzed the specificity of LMNB1 mRNA expression level in LUAD and its effect on prognosis from TCGA data. SiRNAs were used to knock down LMNB1 in the A549 cell line, and the knockdown effect was identified by western blotting and qRT-PCR. Through CCK8 cell proliferation assay, wound healing assay, TRAP, cloning formation Assay, DNase I-TUNEL assay, ATAC-seq, immunofluorescence, FISH, in vivo mouse xenograft studies, etc, we evaluated the influence and mechanism of LMNB1 on LUAD cell line proliferation in vitro and in vivo.ResultsAccording to bioinformatics analysis, LMNB1 is substantially abundant in LUAD tissues and is associated with tumor stage and patient survival (P in vivo mouse xenograft experiments showed that the tumor volume of the LMNB1-silenced group was significantly reduced, compared to that of the control group (P < 0.01), and the proliferation biomarker Ki-67 level (P < 0.01) was considerably reduced.ConclusionsOverexpression of LMNB1 in LUAD cells is significant, which has excellent potential to be an indicator for evaluating the clinical prognosis of LUAD patients and a target for precise treatment.

Published
2022

150. Glass-ceramics with internally crystallized pyrochlore for the immobilization of uranium wastes

Author

Li Jiangbo, Hua Xie, Lielin Wang, Zhiqiang Feng, and Deng Sihao

Subjects
Materials science, Pyrochlore, chemistry.chemical_element, 02 engineering and technology, engineering.material, 01 natural sciences, X-ray photoelectron spectroscopy, 0103 physical sciences, Materials Chemistry, Ceramic, 010302 applied physics, Valence (chemistry), Process Chemistry and Technology, Treatment method, Uranium, 021001 nanoscience & nanotechnology, Microstructure, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, visual_art, Phase composition, Ceramics and Composites, visual_art.visual_art_medium, engineering, 0210 nano-technology, Nuclear chemistry
Abstract

In this work, pyrochlore glass-ceramics (GCs)for uranium immobilization were synthesized by a pretreatment and melting-heat treatment method. The effects of different uranium contents on the phase composition, microstructure, uranium valence and chemical durability of the glass-ceramics were systematically investigated. With increasing uranium content, pyrochlore was always the dominant phase internally crystallized in the glass. CaAl2Si2O8, UTi2O6 and U3O8were gradually observed as minor phases in the glass-ceramics. The growth of pyrochlore enriched with uranium at different uranium contents and the overall distribution of uranium in the glass-ceramics were revealed by SEM. The uranium valence states in the samples were confirmed by XPS to be a mixture of tetravalent and hexavalent states. In addition, the GC3 sample with a high uranium waste content of 16.96 wt% exhibited a low uranium leaching rate.

Published
2019

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