1,227 results on '"Martin A.J."'
Search Results
102. 2083P Association between VTE location and risk of recurrent, bleeding and death in the international prospective TESEO SEOM cancer cohort
- Author
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Lozano, R. Martín, Palma, M., Gonzalez, A. Rodriguez, Perez, J. Rubio, Perez, I. Fernandez, Escobar, I. Garcia, Adrian, S. Garcia, Crespo, J.A. Santiago, PedRoche, C. Diaz, Rebollo, M.T. Antonio, Morales, M.J. Ortiz, García, M.E. Guirao, del Prado, P. Martinez, De Herreros, M. Garcia, Porta-Balanya, R., Covela, M., Morán, L. Ortega, de Castro, E. Martinez, Segura, P. Pérez, and Martin, A.J. Munoz
- Published
- 2023
- Full Text
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103. Synthesis of 2 1 -carboxy-D-arabinitol-1-phosphate in French bean (Phaseolus vulgaris L.): a search for precursors
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Martindale, Wayne, Parry, Martin A.J., Andralojc, P. John, and Keys, Alfred J.
- Published
- 1997
104. Altered Rubisco activity and amounts of a daytime tight-binding inhibitor in transgenic tobacco expressing limiting amounts of phosphoribulokinase
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Paul, Matthew J., Andralojc, P. John, Banks, Fiona M., Parry, Martin A.J., Knight, Jacqui S., Gray, John C., and Keys, Alfred J.
- Published
- 1996
105. Climatic patterns in equatorial and southern Africa from 30,000 to 10,000 years ago reconstructed from terrestrial and near-shore proxy data
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Gasse, Françoise, Chalié, Françoise, Vincens, Annie, Williams, Martin A.J., and Williamson, David
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- 2008
- Full Text
- View/download PDF
106. Overcoming the limitations of Rubisco: fantasy or realistic prospect?
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Orr, Douglas J. and Parry, Martin A.J.
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- 2020
- Full Text
- View/download PDF
107. Grasses of different [C.sub.4] subtypes reveal leaf traits related to drought tolerance in their natural habitats: changes in structure, water potential, and amino acid content
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Carmo-Silva, Ana E., Francisco, Ana, Powers, Stephen J., Keys, Alfred J., Ascensao, Lia, Parry, Martin A.J., and Arrabaca, Maria Celeste
- Subjects
Grasses -- Varieties ,Droughts -- United States ,Droughts -- Environmental aspects ,Plants -- Evolution ,Plants -- Analysis ,Biological sciences - Abstract
Three grasses (Poaceae) of different [C.sub.4] subtypes, Paspalum dilatatum (NADP-malic enzyme [ME]), Cynodon dactylon (NAD-ME) and Zoysia japonica (phosphoenolpyruvate carboxykinase), occur in natural habitats that differ in annual rainfall. Their leaf characteristics were studied to identify traits related to drought tolerance. Plants were grown in pots, and water deficit was gradually induced by withholding water. Leaves of Z japonica had the greatest and P. dilatatum the lowest relative dry matter content. Transverse sections of leaves that developed during the water deficit showed little change compared to control leaves, consistent with low phenotypic plasticity. Anatomical features distinguished the three species, with xeromorphic characteristics most strongly represented in Z. japonica. The leaf relative water content (RWC) decreased with the soil water content similarly for the three grasses. However, at 80% RWC, the leaf water potential was -3.1 MPa for Z. japonica and only -1.3 MPa for P. dilatatum and C. dactylon. Soluble amino acids, especially proline, increased as RWC decreased in leaves of C. dactylon and Z. japonica. Phenylalanine, valine, leucine, and isoleucine increased more in Z. japonica than in the other two species. The results provide evidence that C. dactylon and, especially, Z japonica have evolved leaf traits better suited to arid habitats. Key words: C4 grasses; Cynodon dactylon; drought stress; leaf anatomy; Paspalum dilatatum; Poaceae; water deficit; Zoysia japonica. doi: 10.3732/ajb.0800224
- Published
- 2009
108. Measurement of αs with radiative hadronic events
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Abbiendi, G., Ainsley, C., Åkesson, P.F., Alexander, G., Anagnostou, G., Anderson, K.J., Asai, S., Axen, D., Bailey, I., Barberio, E., Barillari, T., Barlow, R.J., Batley, R.J., Bechtle, P., Behnke, T., Bell, K.W., Bell, P.J., Bella, G., Bellerive, A., Benelli, G., Bethke, S., Biebel, O., Boeriu, O., Bock, P., Boutemeur, M., Braibant, S., Brown, R.M., Burckhart, H.J., Campana, S., Capiluppi, P., Carnegie, R.K., Carter, A.A., Carter, J.R., Chang, C.Y., Charlton, D.G., Ciocca, C., Csilling, A., Cuffiani, M., Dado, S., Dallavalle, M., De Roeck, A., De Wolf, E.A., Desch, K., Dienes, B., Dubbert, J., Duchovni, E., Duckeck, G., Duerdoth, I.P., Etzion, E., Fabbri, F., Ferrari, P., Fiedler, F., Fleck, I., Ford, M., Frey, A., Gagnon, P., Gary, J.W., Geich-Gimbel, C., Giacomelli, G., Giacomelli, P., Giunta, M., Goldberg, J., Gross, E., Grunhaus, J., Gruwé, M., Gupta, A., Hajdu, C., Hamann, M., Hanson, G.G., Harel, A., Hauschild, M., Hawkes, C.M., Hawkings, R., Herten, G., Heuer, R.D., Hill, J.C., Horváth, D., Igo-Kemenes, P., Ishii, K., Jeremie, H., Jovanovic, P., Junk, T.R., Kanzaki, J., Karlen, D., Kawagoe, K., Kawamoto, T., Keeler, R.K., Kellogg, R.G., Kennedy, B.W., Kluth, S., Kobayashi, T., Kobel, M., Komamiya, S., Krämer, T., Krasznahorkay Jr., A., Krieger, P., von Krogh, J., Kuhl, T., Kupper, M., Lafferty, G.D., Landsman, H., Lanske, D., Lellouch, D., Letts, J., Levinson, L., Lillich, J., Lloyd, S.L., Loebinger, F.K., Lu, J., Ludwig, A., Ludwig, J., Mader, W., Marcellini, S., Martin, A.J., Mashimo, T., Mättig, P., McKenna, J., McPherson, R.A., Meijers, F., Menges, W., Merritt, F.S., Mes, H., Meyer, N., Michelini, A., Mihara, S., Mikenberg, G., Miller, D.J., Mohr, W., Mori, T., Mutter, A., Nagai, K., Nakamura, I., Nanjo, H., Neal, H.A., O’Neale, S.W., Oh, A., Oreglia, M.J., Orito, S., Pahl, C., Pásztor, G., Pater, J.R., Pilcher, J.E., Pinfold, J., Plane, D.E., Pooth, O., Przybycień, M., Quadt, A., Rabbertz, K., Rembser, C., Renkel, P., Roney, J.M., Rossi, A.M., Rozen, Y., Runge, K., Sachs, K., Saeki, T., Sarkisyan, E.K.G., Schaile, A.D., Schaile, O., Scharff-Hansen, P., Schieck, J., Schörner-Sadenius, T., Schröder, M., Schumacher, M., Seuster, R., Shears, T.G., Shen, B.C., Sherwood, P., Skuja, A., Smith, A.M., Sobie, R., Söldner-Rembold, S., Spano, F., Stahl, A., Strom, D., Ströhmer, R., Tarem, S., Tasevsky, M., Teuscher, R., Thomson, M.A., Torrence, E., Toya, D., Trigger, I., Trócsányi, Z., Tsur, E., Turner-Watson, M.F., Ueda, I., Ujvári, B., Vollmer, C.F., Vannerem, P., Vértesi, R., Verzocchi, M., Voss, H., Vossebeld, J., Ward, C.P., Ward, D.R., Watkins, P.M., Watson, A.T., Watson, N.K., Wells, P.S., Wengler, T., Wermes, N., Wilson, G.W., Wilson, J.A., Wolf, G., Wyatt, T.R., Yamashita, S., Zer-Zion, D., Zivkovic, L., and The OPAL Collaboration
- Published
- 2008
- Full Text
- View/download PDF
109. Bose–Einstein study of position–momentum correlations of charged pions in hadronic Z0 decays
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Abbiendi, G., Ainsley, C., Åkesson, P.F., Alexander, G., Anagnostou, G., Anderson, K.J., Asai, S., Axen, D., Bailey, I., Barberio, E., Barillari, T., Barlow, R.J., Batley, R.J., Bechtle, P., Behnke, T., Bell, K.W., Bell, P.J., Bella, G., Bellerive, A., Benelli, G., Bethke, S., Biebel, O., Boeriu, O., Bock, P., Boutemeur, M., Braibant, S., Brown, R.M., Burckhart, H.J., Campana, S., Capiluppi, P., Carnegie, R.K., Carter, A.A., Carter, J.R., Chang, C.Y., Charlton, D.G., Ciocca, C., Csilling, A., Cuffiani, M., Dado, S., Dallavalle, G.M., De Roeck, A., De Wolf, E.A., Desch, K., Dienes, B., Dubbert, J., Duchovni, E., Duckeck, G., Duerdoth, I.P., Etzion, E., Fabbri, F., Ferrari, P., Fiedler, F., Fleck, I., Ford, M., Frey, A., Gagnon, P., Gary, J.W., Geich-Gimbel, C., Giacomelli, G., Giacomelli, P., Giunta, M., Goldberg, J., Gross, E., Grunhaus, J., Gruwé, M., Gupta, A., Hajdu, C., Hamann, M., Hanson, G.G., Harel, A., Hauschild, M., Hawkes, C.M., Hawkings, R., Herten, G., Heuer, R.D., Hill, J.C., Horváth, D., Igo-Kemenes, P., Ishii, K., Jeremie, H., Jovanovic, P., Junk, T.R., Kanzaki, J., Karlen, D., Kawagoe, K., Kawamoto, T., Keeler, R.K., Kellogg, R.G., Kennedy, B.W., Kluth, S., Kobayashi, T., Kobel, M., Komamiya, S., Krämer, T., Krasznahorkay Jr., A., Krieger, P., von Krogh, J., Kuhl, T., Kupper, M., Lafferty, G.D., Landsman, H., Lanske, D., Lellouch, D., Letts, J., Levinson, L., Lillich, J., Lloyd, S.L., Loebinger, F.K., Lu, J., Ludwig, A., Ludwig, J., Mader, W., Marcellini, S., Martin, A.J., Mashimo, T., Mättig, P., McKenna, J., McPherson, R.A., Meijers, F., Menges, W., Merritt, F.S., Mes, H., Meyer, N., Michelini, A., Mihara, S., Mikenberg, G., Miller, D.J., Mohr, W., Mori, T., Mutter, A., Nagai, K., Nakamura, I., Nanjo, H., Neal, H.A., O’Neale, S.W., Oh, A., Oreglia, M.J., Orito, S., Pahl, C., Pásztor, G., Pater, J.R., Pilcher, J.E., Pinfold, J., Plane, D.E., Pooth, O., Przybycień, M., Quadt, A., Rabbertz, K., Rembser, C., Renkel, P., Roney, J.M., Rossi, A.M., Rozen, Y., Runge, K., Sachs, K., Saeki, T., Sarkisyan, E.K.G., Schaile, A.D., Schaile, O., Scharff-Hansen, P., Schieck, J., Schörner-Sadenius, T., Schröder, M., Schumacher, M., Seuster, R., Shears, T.G., Shen, B.C., Sherwood, P., Skuja, A., Smith, A.M., Sobie, R., Söldner-Rembold, S., Spano, F., Stahl, A., Strom, D., Ströhmer, R., Tarem, S., Tasevsky, M., Teuscher, R., Thomson, M.A., Torrence, E., Toya, D., Trigger, I., Trócsányi, Z., Tsur, E., Turner-Watson, M.F., Ueda, I., Ujvári, B., Vollmer, C.F., Vannerem, P., Vértesi, R., Verzocchi, M., Voss, H., Vossebeld, J., Ward, C.P., Ward, D.R., Watkins, P.M., Watson, A.T., Watson, N.K., Wells, P.S., Wengler, T., Wermes, N., Wilson, G.W., Wilson, J.A., Wolf, G., Wyatt, T.R., Yamashita, S., Zer-Zion, D., Zivkovic, L., and The OPAL Collaboration
- Published
- 2007
- Full Text
- View/download PDF
110. Measurement of the e+e-→W+W- cross section and W decay branching fractions at LEP
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Abbiendi, G., Ainsley, C., Åkesson, P.F., Alexander, G., Anagnostou, G., Anderson, K.J., Asai, S., Axen, D., Bailey, I., Barberio, E., Barillari, T., Barlow, R.J., Batley, R.J., Bechtle, P., Behnke, T., Bell, K.W., Bell, P.J., Bella, G., Bellerive, A., Benelli, G., Bethke, S., Biebel, O., Boeriu, O., Bock, P., Boutemeur, M., Braibant, S., Brown, R.M., Burckhart, H.J., Campana, S., Capiluppi, P., Carnegie, R.K., Carter, A.A., Carter, J.R., Chang, C.Y., Charlton, D.G., Ciocca, C., Csilling, A., Cuffiani, M., Dado, S., Dallavalle, M., De Roeck, A., De Wolf, E.A., Desch, K., Dienes, B., Dubbert, J., Duchovni, E., Duckeck, G., Duerdoth, I.P., Etzion, E., Fabbri, F., Ferrari, P., Fiedler, F., Fleck, I., Ford, M., Frey, A., Gagnon, P., Gary, J.W., Geich-Gimbel, C., Giacomelli, G., Giacomelli, P., Giunta, M., Goldberg, J., Gross, E., Grunhaus, J., Gruwé, M., Gupta, A., Hajdu, C., Hamann, M., Hanson, G.G., Harel, A., Hauschild, M., Hawkes, C.M., Hawkings, R., Herten, G., Heuer, R.D., Hill, J.C., Horváth, D., Igo-Kemenes, P., Ishii, K., Jeremie, H., Jovanovic, P., Junk, T.R., Kanzaki, J., Karlen, D., Kawagoe, K., Kawamoto, T., Keeler, R.K., Kellogg, R.G., Kennedy, B.W., Kluth, S., Kobayashi, T., Kobel, M., Komamiya, S., Krämer, T., Krasznahorkay Jr., A., Krieger, P., von Krogh, J., Kuhl, T., Kupper, M., Lafferty, G.D., Landsman, H., Lanske, D., Lellouch, D., Letts, J., Levinson, L., Lillich, J., Lloyd, S.L., Loebinger, F.K., Lu, J., Ludwig, A., Ludwig, J., Mader, W., Marcellini, S., Martin, A.J., Mashimo, T., Mättig, P., McKenna, J., McPherson, R.A., Meijers, F., Menges, W., Merritt, F.S., Mes, H., Meyer, N., Michelini, A., Mihara, S., Mikenberg, G., Miller, D.J., Mohr, W., Mori, T., Mutter, A., Nagai, K., Nakamura, I., Nanjo, H., Neal, H.A., O’Neale, S.W., Oh, A., Oreglia, M.J., Orito, S., Pahl, C., Pásztor, G., Pater, J.R., Pilcher, J.E., Pinfold, J., Plane, D.E., Pooth, O., Przybycień, M., Quadt, A., Rabbertz, K., Rembser, C., Renkel, P., Roney, J.M., Rossi, A.M., Rozen, Y., Runge, K., Sachs, K., Saeki, T., Sarkisyan, E.K.G., Schaile, A.D., Schaile, O., Scharff-Hansen, P., Schieck, J., Schörner-Sadenius, T., Schröder, M., Schumacher, M., Seuster, R., Shears, T.G., Shen, B.C., Sherwood, P., Skuja, A., Smith, A.M., Sobie, R., Söldner-Rembold, S., Spano, F., Stahl, A., Strom, D., Ströhmer, R., Tarem, S., Tasevsky, M., Teuscher, R., Thomson, M.A., Torrence, E., Toya, D., Trigger, I., Trócsányi, Z., Tsur, E., Turner-Watson, M.F., Ueda, I., Ujvári, B., Vollmer, C.F., Vannerem, P., Vértesi, R., Verzocchi, M., Voss, H., Vossebeld, J., Ward, C.P., Ward, D.R., Watkins, P.M., Watson, A.T., Watson, N.K., Wells, P.S., Wengler, T., Wermes, N., Wilson, G.W., Wilson, J.A., Wolf, G., Wyatt, T.R., Yamashita, S., Zer-Zion, D., Zivkovic, L., and The OPAL Collaboration
- Published
- 2007
- Full Text
- View/download PDF
111. Search for invisibly decaying Higgs bosons with large decay width using the OPAL detector at LEP
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Abbiendi, G., Ainsley, C., Åkesson, P.F., Alexander, G., Anagnostou, G., Anderson, K.J., Asai, S., Axen, D., Bailey, I., Barberio, E., Barillari, T., Barlow, R.J., Batley, R.J., Bechtle, P., Behnke, T., Bell, K.W., Bell, P.J., Bella, G., Bellerive, A., Benelli, G., Bethke, S., Biebel, O., Boeriu, O., Bock, P., Boutemeur, M., Braibant, S., Brown, R.M., Burckhart, H.J., Campana, S., Capiluppi, P., Carnegie, R.K., Carter, A.A., Carter, J.R., Chang, C.Y., Charlton, D.G., Ciocca, C., Csilling, A., Cuffiani, M., Dado, S., De Roeck, A., De Wolf, E.A., Desch, K., Dienes, B., Dubbert, J., Duchovni, E., Duckeck, G., Duerdoth, I.P., Etzion, E., Fabbri, F., Ferrari, P., Fiedler, F., Fleck, I., Ford, M., Frey, A., Gagnon, P., Gary, J.W., Geich-Gimbel, C., Giacomelli, G., Giacomelli, P., Giunta, M., Goldberg, J., Gross, E., Grunhaus, J., Gruwé, M., Gupta, A., Hajdu, C., Hamann, M., Hanson, G.G., Harel, A., Hauschild, M., Hawkes, C.M., Hawkings, R., Herten, G., Heuer, R.D., Hill, J.C., Horváth, D., Igo-Kemenes, P., Ishii, K., Jeremie, H., Jovanovic, P., Junk, T.R., Kanzaki, J., Karlen, D., Kawagoe, K., Kawamoto, T., Keeler, R.K., Kellogg, R.G., Kennedy, B.W., Kluth, S., Kobayashi, T., Kobel, M., Komamiya, S., Krämer, T., Krasznahorkay Jr., A., Krieger, P., von Krogh, J., Kuhl, T., Kupper, M., Lafferty, G.D., Landsman, H., Lanske, D., Lellouch, D., Letts, J., Levinson, L., Lillich, J., Lloyd, S.L., Loebinger, F.K., Lu, J., Ludwig, A., Ludwig, J., Mader, W., Marcellini, S., Martin, A.J., Mashimo, T., Mättig, P., McKenna, J., McPherson, R.A., Meijers, F., Menges, W., Merritt, F.S., Mes, H., Meyer, N., Michelini, A., Mihara, S., Mikenberg, G., Miller, D.J., Mohr, W., Mori, T., Mutter, A., Nagai, K., Nakamura, I., Nanjo, H., Neal, H.A., Nisius, R., O’Neale, S.W., Oh, A., Oreglia, M.J., Orito, S., Pahl, C., Pásztor, G., Pater, J.R., Pilcher, J.E., Pinfold, J., Plane, D.E., Pooth, O., Przybycień, M., Quadt, A., Rabbertz, K., Rembser, C., Renkel, P., Roney, J.M., Rossi, A.M., Rozen, Y., Runge, K., Sachs, K., Saeki, T., Sarkisyan, E.K.G., Schaile, A.D., Schaile, O., Scharff-Hansen, P., Schieck, J., Schörner-Sadenius, T., Schröder, M., Schumacher, M., Seuster, R., Shears, T.G., Shen, B.C., Sherwood, P., Skuja, A., Smith, A.M., Sobie, R., Söldner-Rembold, S., Spano, F., Stahl, A., Strom, D., Ströhmer, R., Tarem, S., Tasevsky, M., Teuscher, R., Thomson, M.A., Torrence, E., Toya, D., Tran, P., Trigger, I., Trócsányi, Z., Tsur, E., Turner-Watson, M.F., Ueda, I., Ujvári, B., Vollmer, C.F., Vannerem, P., Vértesi, R., Verzocchi, M., Voss, H., Vossebeld, J., Ward, C.P., Ward, D.R., Watkins, P.M., Watson, A.T., Watson, N.K., Wells, P.S., Wengler, T., Wermes, N., Wilson, G.W., Wilson, J.A., Wolf, G., Wyatt, T.R., Yamashita, S., Zer-Zion, D., Zivkovic, L., and The OPAL Collaboration
- Published
- 2007
- Full Text
- View/download PDF
112. Search for neutral MSSM Higgs bosons at LEP
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Schael, S., Barate, R., Brunelière, R., De Bonis, I., Decamp, D., Goy, C., Jézéquel, S., Lees, J.-P., Martin, F., Merle, E., Minard, M.-N., Pietrzyk, B., Trocmé, B., Bravo, S., Casado, M.P., Chmeissani, M., Crespo, J.M., Fernandez, E., Fernandez-Bosman, M., Garrido, L., Martinez, M., Pacheco, A., Ruiz, H., Colaleo, A., Creanza, D., De Filippis, N., de Palma, M., Iaselli, G., Maggi, G., Maggi, M., Nuzzo, S., Ranieri, A., Raso, G., Ruggieri, F., Selvaggi, G., Silvestris, L., Tempesta, P., Tricomi, A., Zito, G., Huang, X., Lin, J., Ouyang, Q., Wang, T., Xie, Y., Xu, R., Xue, S., Zhang, J., Zhang, L., Zhao, W., Abbaneo, D., Barklow, T., Buchmüller, O., Cattaneo, M., Clerbaux, B., Drevermann, H., Forty, R.W., Frank, M., Gianotti, F., Hansen, J.B., Harvey, J., Hutchcroft, D.E., Janot, P., Jost, B., Kado, M., Mato, P., Moutoussi, A., Ranjard, F., Rolandi, L., Schlatter, D., Teubert, F., Valassi, A., Videau, I., Badaud, F., Dessagne, S., Falvard, A., Fayolle, D., Gay, P., Jousset, J., Michel, B., Monteil, S., Pallin, D., Pascolo, J.M., Perret, P., Hansen, J.D., Hansen, J.R., Hansen, P.H., Kraan, A.C., Nilsson, B.S., Kyriakis, A., Markou, C., Simopoulou, E., Vayaki, A., Zachariadou, K., Blondel, A., Brient, J.-C., Machefert, F., Rougé, A., Videau, H., Ciulli, V., Focardi, E., Parrini, G., Antonelli, A., Antonelli, M., Bencivenni, G., Bossi, F., Capon, G., Cerutti, F., Chiarella, V., Mannocchi, G., Laurelli, P., Mannocchi, G., Murtas, G.P., Passalacqua, L., Kennedy, J., Lynch, J.G., Negus, P., O’Shea, V., Thompson, A.S., Wasserbaech, S., Cavanaugh, R., Dhamotharan, S., Geweniger, C., Hanke, P., Hepp, V., Kluge, E.E., Putzer, A., Stenzel, H., Tittel, K., Wunsch, M., Beuselinck, R., Cameron, W., Davies, G., Dornan, P.J., Girone, M., Marinelli, N., Nowell, J., Rutherford, S.A., Sedgbeer, J.K., Thompson, J.C., White, R., Ghete, V.M., Girtler, P., Kneringer, E., Kuhn, D., Rudolph, G., Bouhova-Thacker, E., Bowdery, C.K., Clarke, D.P., Ellis, G., Finch, A.J., Foster, F., Hughes, G., Jones, R.W.L., Pearson, M.R., Robertson, N.A., Smizanska, M., van der Aa, O., Delaere, C., Leibenguth, G., Lemaitre, V., Blumenschein, U., Hölldorfer, F., Jakobs, K., Kayser, F., Müller, A.-S., Renk, B., Sander, H.-G., Schmeling, S., Wachsmuth, H., Zeitnitz, C., Ziegler, T., Bonissent, A., Coyle, P., Curtil, C., Ealet, A., Fouchez, D., Payre, P., Tilquin, A., Ragusa, F., David, A., Dietl, H., Ganis, G., Hüttmann, K., Lütjens, G., Männer, W., Moser, H.-G., Settles, R., Villegas, M., Wolf, G., Boucrot, J., Callot, O., Davier, M., Duflot, L., Grivaz, J.-F., Heusse, P., Jacholkowska, A., Serin, L., Veillet, J.-J., Azzurri, P., Bagliesi, G., Boccali, T., Foà, L., Giammanco, A., Giassi, A., Ligabue, F., Messineo, A., Palla, F., Sanguinetti, G., Sciabà, A., Sguazzoni, G., Spagnolo, P., Tenchini, R., Venturi, A., Verdini, P.G., Awunor, O., Blair, G.A., Cowan, G., Garcia-Bellido, A., Green, M.G., Medcalf, T., Misiejuk, A., Strong, J.A., Teixeira-Dias, P., Clifft, R.W., Edgecock, T.R., Norton, P.R., Tomalin, I.R., Ward, J.J., Bloch-Devaux, B., Boumediene, D., Colas, P., Fabbro, B., Lançon, E., Lemaire, M.-C., Locci, E., Perez, P., Rander, J., Tuchming, B., Vallage, B., Litke, A.M., Taylor, G., Booth, C.N., Cartwright, S., Combley, F., Hodgson, P.N., Lehto, M., Thompson, L.F., Böhrer, A., Brandt, S., Grupen, C., Hess, J., Ngac, A., Prange, G., Borean, C., Giannini, G., He, H., Putz, J., Rothberg, J., Armstrong, S.R., Berkelman, K., Cranmer, K., Ferguson, D.P.S., Gao, Y., González, S., Hayes, O.J., Hu, H., Jin, S., Kile, J., McNamara III, P.A., Nielsen, J., Pan, Y.B., von Wimmersperg-Toeller, J.H., Wiedenmann, W., Wu, J., Wu, S.L., Wu, X., Zobernig, G., Dissertori, G., Abdallah, J., Abreu, P., Adam, W., Adzic, P., Albrecht, T., Alderweireld, T., Alemany-Fernandez, R., Allmendinger, T., Allport, P.P., Amaldi, U., Amapane, N., Amato, S., Anashkin, E., Andreazza, A., Andringa, S., Anjos, N., Antilogus, P., Apel, W.-D., Arnoud, Y., Ask, S., Asman, B., Augustin, J.E., Augustinus, 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L., Perepelitsa, V., Perrotta, A., Petrolini, A., Piedra, J., Pieri, L., Pierre, F., Pimenta, M., Piotto, E., Podobnik, T., Poireau, V., Pol, M.E., Polok, G., Pozdniakov, V., Pukhaeva, N., Pullia, A., Rames, J., Read, A., Rebecchi, P., Rehn, J., Reid, D., Reinhardt, R., Renton, P., Richard, F., Ridky, J., Rivero, M., Rodriguez, D., Romero, A., Ronchese, P., Roudeau, P., Rovelli, T., Ruhlmann-Kleider, V., Ryabtchikov, D., Sadovsky, A., Salmi, L., Salt, J., Sander, C., Savoy-Navarro, A., Schwickerath, U., Segar, A., Sekulin, R., Siebel, M., Sisakian, A., Smadja, G., Smirnova, O., Sokolov, A., Sopczak, A., Sosnowski, R., Spassov, T., Stanitzki, M., Stocchi, A., Strauss, J., Stugu, B., Szczekowski, M., Szeptycka, M., Szumlak, T., Tabarelli, T., Taffard, A.C., Tegenfeldt, F., Timmermans, J., Tkatchev, L., Tobin, M., Todorovova, S., Tome, B., Tonazzo, A., Tortosa, P., Travnicek, P., Treille, D., Tristram, G., Trochimczuk, M., Troncon, C., Turluer, M.-L., Tyapkin, I.A., Tyapkin, P., Tzamarias, S., Uvarov, V., Valenti, G., Van Dam, P., Van Eldik, J., van Remortel, N., Van Vulpen, I., Vegni, G., Veloso, F., Venus, W., Verdier, P., Verzi, V., Vilanova, D., Vitale, L., Vrba, V., Wahlen, H., Washbrook, A.J., Weiser, C., Wicke, D., Wickens, J., Wilkinson, G., Winter, M., Witek, M., Yushchenko, O., Zalewska, A., Zalewski, P., Zavrtanik, D., Zhuravlov, V., Zimin, N.I., Zintchenko, A., Zupan, M., Achard, P., Adriani, O., Aguilar-Benitez, M., Alcaraz, J., Alemanni, G., Allaby, J., Aloisio, A., Alviggi, M.G., Anderhub, H., Andreev, V.P., Anselmo, F., Arefiev, A., Azemoon, T., Aziz, T., Bagnaia, P., Bajo, A., Baksay, G., Baksay, L., Baldew, S.V., Banerjee, S., Banerjee, Sw., Barczyk, A., Barillère, R., Bartalini, P., Basile, M., Batalova, N., Battiston, R., Bay, A., Becattini, F., Becker, U., Behner, F., Bellucci, L., Berbeco, R., Berdugo, J., Berges, P., Bertucci, B., Betev, B.L., Biasini, M., Biglietti, M., Biland, A., Blaising, J.J., Blyth, S.C., Bobbink, G.J., Böhm, A., Boldizsar, L., Borgia, B., Bottai, S., Bourilkov, D., Bourquin, M., Braccini, S., Branson, J.G., Brochu, F., Burger, J.D., Burger, W.J., Cai, X.D., Capell, M., Cara Romeo, G., Carlino, G., Cartacci, A., Casaus, J., Cavallari, F., Cavallo, N., Cecchi, C., Cerrada, M., Chamizo, M., Chang, Y.H., Chemarin, M., Chen, A., Chen, G., Chen, G.M., Chen, H.F., Chen, H.S., Chiefari, G., Cifarelli, L., Cindolo, F., Clare, I., Clare, R., Coignet, G., Colino, N., Costantini, S., de la Cruz, B., Cucciarelli, S., de Asmundis, R., Déglon, P., Debreczeni, J., Degré, A., Dehmelt, K., Deiters, K., della Volpe, D., Delmeire, E., Denes, P., DeNotaristefani, F., De Salvo, A., Diemoz, M., Dierckxsens, M., Dionisi, C., Dittmar, M., Doria, A., Dova, M.T., Duchesneau, D., Duda, M., Echenard, B., Eline, A., El Hage, A., El Mamouni, H., Engler, A., Eppling, F.J., Extermann, P., Falagan, M.A., Falciano, S., Favara, A., Fay, J., Fedin, O., Felcini, M., Ferguson, T., Fesefeldt, H., Fiandrini, E., Field, J.H., Filthaut, F., Fisher, P.H., Fisher, W., Forconi, G., Freudenreich, K., Furetta, C., Galaktionov, Yu., Ganguli, S.N., Garcia-Abia, P., Gataullin, M., Gentile, S., Giagu, S., Gong, Z.F., Grenier, G., Grimm, O., Gruenewald, M.W., Guida, M., Gupta, V.K., Gurtu, A., Gutay, L.J., Haas, D., Hatzifotiadou, D., Hebbeker, T., Hervé, A., Hirschfelder, J., Hofer, H., Hohlmann, M., Holzner, G., Hou, S.R., Hu, J., Jin, B.N., Jindal, P., Jones, L.W., de Jong, P., Josa-Mutuberría, I., Kaur, M., Kienzle-Focacci, M.N., Kim, J.K., Kirkby, J., Kittel, W., Klimentov, A., König, A.C., Kopal, M., Koutsenko, V., Kräber, M., Kraemer, R.W., Krüger, A., Kunin, A., Ladron de Guevara, P., Laktineh, I., Landi, G., Lebeau, M., Lebedev, A., Lebrun, P., Lecomte, P., Lecoq, P., Le Coultre, P., Le Goff, J.M., Leiste, R., Levtchenko, M., Levtchenko, P., Li, C., Likhoded, S., Lin, C.H., Lin, W.T., Linde, F.L., Lista, L., Liu, Z.A., Lohmann, W., Longo, E., Lu, Y.S., Luci, C., Luminari, L., Lustermann, W., Ma, W.G., Malgeri, L., Malinin, A., Ma na, C., Mans, J., Martin, J.P., Marzano, F., Mazumdar, K., McNeil, R.R., Mele, S., Merola, L., Meschini, M., Metzger, W.J., Mihul, A., Milcent, H., Mirabelli, G., Mnich, J., Mohanty, G.B., Muanza, G.S., Muijs, A.J.M., Musicar, B., Musy, M., Nagy, S., Natale, S., Napolitano, M., Nessi-Tedaldi, F., Newman, H., Nisati, A., Novak, T., Nowak, H., Ofierzynski, R., Organtini, G., Pal, I., Palomares, C., Paolucci, P., Paramatti, R., Passaleva, G., Patricelli, S., Paul, T., Pauluzzi, M., Paus, C., Pauss, F., Pedace, M., Pensotti, S., Perret-Gallix, D., Piccolo, D., Pierella, F., Pieri, M., Pioppi, M., Piroué, P.A., Pistolesi, E., Plyaskin, V., Pohl, M., Pojidaev, V., Pothier, J., Prokofiev, D., Rahal-Callot, G., Rahaman, M.A., Raics, P., Raja, N., Ramelli, R., Rancoita, P.G., Ranieri, R., Raspereza, A., Razis, P., Rembeczki, S., Ren, D., Rescigno, M., Reucroft, S., Riemann, S., Riles, K., Roe, B.P., Romero, L., Rosca, A., Rosemann, C., Rosenbleck, C., Rosier-Lees, S., Roth, S., Rubio, J.A., Ruggiero, G., Rykaczewski, H., Sakharov, A., Saremi, S., Sarkar, S., Salicio, J., Sanchez, E., Schäfer, C., Schegelsky, V., Schopper, H., Schotanus, D.J., Sciacca, C., Servoli, L., Shevchenko, S., Shivarov, N., Shoutko, V., Shumilov, E., Shvorob, A., Son, D., Souga, C., Spillantini, P., Steuer, M., Stickland, D.P., Stoyanov, B., Straessner, A., Sudhakar, K., Sultanov, G., Sun, L.Z., Sushkov, S., Suter, H., Swain, J.D., Szillasi, Z., Tang, X.W., Tarjan, P., Tauscher, L., Taylor, L., Tellili, B., Teyssier, D., Timmermans, C., Ting, S.C.C., Ting, S.M., Tonwar, S.C., Tóth, J., Tully, C., Tung, K.L., Ulbricht, J., Valente, E., Van de Walle, R.T., Vasquez, R., Vesztergombi, G., Vetlitsky, I., Viertel, G., Vivargent, M., Vlachos, S., Vodopianov, I., Vogel, H., Vogt, H., Vorobiev, I., Vorobyov, A.A., Wadhwa, M., Wang, Q., Wang, X.L., Wang, Z.M., Weber, M., Wynhoff, S., Xia, L., Xu, Z.Z., Yamamoto, J., Yang, B.Z., Yang, C.G., Yang, H.J., Yang, M., Yeh, S.C., Zalite, An., Zalite, Yu., Zhang, Z.P., Zhao, J., Zhu, G.Y., Zhu, R.Y., Zhuang, H.L., Zichichi, A., Zimmermann, B., Zöller, M., Abbiendi, G., Ainsley, C., Åkesson, P.F., Alexander, G., Allison, J., Amaral, P., Anagnostou, G., Anderson, K.J., Asai, S., Axen, D., Azuelos, G., Bailey, I., Barberio, E., Barillari, T., Barlow, R.J., Batley, R.J., Bechtle, P., Behnke, T., Bell, K.W., Bell, P.J., Bella, G., Bellerive, A., Benelli, G., Bethke, S., Biebel, O., Boeriu, O., Bock, P., Boutemeur, M., Braibant, S., Brigliadori, L., Brown, R.M., Buesser, K., Burckhart, H.J., Campana, S., Carnegie, R.K., Carter, A.A., Carter, J.R., Chang, C.Y., Charlton, D.G., Ciocca, C., Csilling, A., Cuffiani, M., Dado, S., de Jong, S., De Roeck, A., De Wolf, E.A., Desch, K., Dienes, B., Donkers, M., Dubbert, J., Duchovni, E., Duckeck, G., Duerdoth, I.P., Etzion, E., Fabbri, F., Feld, L., Ferrari, P., Fiedler, F., Fleck, I., Ford, M., Frey, A., Gagnon, P., Gary, J.W., Gascon-Shotkin, S.M., Gaycken, G., Geich-Gimbel, C., Giacomelli, G., Giacomelli, P., Giunta, M., Goldberg, J., Gross, E., Grunhaus, J., Gruwé, M., Günther, P.O., Gupta, A., Hajdu, C., Hamann, M., Hanson, G.G., Harel, A., Hauschild, M., Hawkes, C.M., Hawkings, R., Hemingway, R.J., Herten, G., Heuer, R.D., Hill, J.C., Hoffman, K., Horváth, D., Igo-Kemenes, P., Ishii, K., Jeremie, H., Jost, U., Jovanovic, P., Junk, T.R., Kanaya, N., Kanzaki, J., Karlen, D., Kawagoe, K., Kawamoto, T., Keeler, R.K., Kellogg, R.G., Kennedy, B.W., Kluth, S., Kobayashi, T., Kobel, M., Komamiya, S., Krämer, T., Krieger, P., von Krogh, J., Kruger, K., Kuhl, T., Kupper, M., Lafferty, G.D., Landsman, H., Lanske, D., Layter, J.G., Lellouch, D., Letts, J., Levinson, L., Lillich, J., Lloyd, S.L., Loebinger, F.K., Lu, J., Ludwig, A., Ludwig, J., Mader, W., Marcellini, S., Martin, A.J., Masetti, G., Mashimo, T., Mättig, P., McKenna, J., McPherson, R.A., Meijers, F., Menges, W., Merritt, F.S., Mes, H., Meyer, N., Michelini, A., Mihara, S., Mikenberg, G., Miller, D.J., Moed, S., Mohr, W., Mori, T., Mutter, A., Nagai, K., Nakamura, I., Nanjo, H., Neal, H.A., Nisius, R., O’Neale, S.W., Oh, A., Oreglia, M.J., Orito, S., Pahl, C., Pásztor, G., Pater, J.R., Pilcher, J.E., Pinfold, J., Plane, D.E., Poli, B., Pooth, O., Przybycień, M., Quadt, A., Rabbertz, K., Rembser, C., Renkel, P., Roney, J.M., Rozen, Y., Runge, K., Sachs, K., Saeki, T., Sarkisyan, E.K.G., Schaile, A.D., Schaile, O., Scharff-Hansen, P., Schieck, J., Schörner-Sadenius, T., Schröder, M., Schumacher, M., Scott, W.G., Seuster, R., Shears, T.G., Shen, B.C., Sherwood, P., Skuja, A., Smith, A.M., Sobie, R., Söldner-Rembold, S., Spano, F., Stahl, A., Strom, D., Ströhmer, R., Tarem, S., Tasevsky, M., Teuscher, R., Thomson, M.A., Torrence, E., Toya, D., Tran, P., Trigger, I., Trócsányi, Z., Tsur, E., Turner-Watson, M.F., Ueda, I., Ujvári, B., Vollmer, C.F., Vannerem, P., Vértesi, R., Verzocchi, M., Voss, H., Vossebeld, J., Ward, C.P., Ward, D.R., Watkins, P.M., Watson, A.T., Watson, N.K., Wells, P.S., Wengler, T., Wermes, N., Wilson, G.W., Wilson, J.A., Wolf, G., Wyatt, T.R., Yamashita, S., Zer-Zion, D., Zivkovic, L., Heinemeyer, S., Pilaftsis, A., Weiglein, G., and The LEP Working Group for Higgs Boson Searches
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- 2006
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113. Measurement of the strong coupling αS from four-jet observables in e+e- annihilation
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Abbiendi, G., Ainsley, C., Åkesson, P.F., Alexander, G., Anagnostou, G., Anderson, K.J., Asai, S., Axen, D., Bailey, I., Barberio, E., Barillari, T., Barlow, R.J., Batley, R.J., Bechtle, P., Behnke, T., Bell, K.W., Bell, P.J., Bella, G., Bellerive, A., Benelli, G., Bethke, S., Biebel, O., Boeriu, O., Bock, P., Boutemeur, M., Braibant, S., Brown, R.M., Burckhart, H.J., Campana, S., Capiluppi, P., Carnegie, R.K., Carter, A.A., Carter, J.R., Chang, C.Y., Charlton, D.G., Ciocca, C., Csilling, A., Cuffiani, M., Dado, S., De Roeck, A., De Wolf, E.A., Desch, K., Dienes, B., Dubbert, J., Duchovni, E., Duckeck, G., Duerdoth, I.P., Etzion, E., Fabbri, F., Ferrari, P., Fiedler, F., Fleck, I., Ford, M., Frey, A., Gagnon, P., Gary, J.W., Geich-Gimbel, C., Giacomelli, G., Giacomelli, P., Giunta, M., Goldberg, J., Gross, E., Grunhaus, J., Gruwé, M., Günther, P.O., Gupta, A., Hajdu, C., Hamann, M., Hanson, G.G., Harel, A., Hauschild, M., Hawkes, C.M., Hawkings, R., Hemingway, R.J., Herten, G., Heuer, R.D., Hill, J.C., Horváth, D., Igo-Kemenes, P., Ishii, K., Jeremie, H., Jovanovic, P., Junk, T.R., Kanzaki, J., Karlen, D., Kawagoe, K., Kawamoto, T., Keeler, R.K., Kellogg, R.G., Kennedy, B.W., Kluth, S., Kobayashi, T., Kobel, M., Komamiya, S., Krämer, T., Krasznahorkay, A., Krieger, P., von Krogh, J., Kuhl, T., Kupper, M., Lafferty, G.D., Landsman, H., Lanske, D., Lellouch, D., Letts, J., Levinson, L., Lillich, J., Lloyd, S.L., Loebinger, F.K., Lu, J., Ludwig, A., Ludwig, J., Mader, W., Marcellini, S., Martin, A.J., Mashimo, T., Mättig, P., McKenna, J., McPherson, R.A., Meijers, F., Menges, W., Merritt, F.S., Mes, H., Meyer, N., Michelini, A., Mihara, S., Mikenberg, G., Miller, D.J., Mohr, W., Mori, T., Mutter, A., Nagai, K., Nakamura, I., Nanjo, H., Neal, H.A., Nisius, R., O’Neale, S.W., Oh, A., Oreglia, M.J., Orito, S., Pahl, C., Pásztor, G., Pater, J.R., Pilcher, J.E., Pinfold, J., Plane, D.E., Pooth, O., Przybycień, M., Quadt, A., Rabbertz, K., Rembser, C., Renkel, P., Roney, J.M., Rossi, A.M., Rozen, Y., Runge, K., Sachs, K., Saeki, T., Sarkisyan, E.K.G., Schaile, A.D., Schaile, O., Scharff-Hansen, P., Schieck, J., Schörner-Sadenius, T., Schröder, M., Schumacher, M., Seuster, R., Shears, T.G., Shen, B.C., Sherwood, P., Skuja, A., Smith, A.M., Sobie, R., Söldner-Rembold, S., Spano, F., Stahl, A., Strom, D., Ströhmer, R., Tarem, S., Tasevsky, M., Teuscher, R., Thomson, M.A., Torrence, E., Toya, D., Tran, P., Trigger, I., Trócsányi, Z., Tsur, E., Turner-Watson, M.F., Ueda, I., Ujvári, B., Vollmer, C.F., Vannerem, P., Vértesi, R., Verzocchi, M., Voss, H., Vossebeld, J., Ward, C.P., Ward, D.R., Watkins, P.M., Watson, A.T., Watson, N.K., Wells, P.S., Wengler, T., Wermes, N., Wilson, G.W., Wilson, J.A., Wolf, G., Wyatt, T.R., Yamashita, S., Zer-Zion, D., Zivkovic, L., and The OPAL Collaboration
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- 2006
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114. Health-related quality of life (HRQL) in a randomized phase III trial of enzalutamide with standard first-line therapy for metastatic, hormone-sensitive prostate cancer (mHSPC): ENZAMET (ANZUP 1304), an ANZUP-led, international, co-operative group trial.
- Author
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North S.A., Caffrey J.M., McDermott R., Parnis F., Sweeney C.J., Zielinski R., Thomson A., Tan T.H., Sandhu S.K., Reaume M.N., Pook D.W., Stockler M.R., Martin A.J., Dhillon H., Davis I.D., Chi K.N., Chowdhury S., Horvath L.G., Lawrence N.J., Marx G.M., North S.A., Caffrey J.M., McDermott R., Parnis F., Sweeney C.J., Zielinski R., Thomson A., Tan T.H., Sandhu S.K., Reaume M.N., Pook D.W., Stockler M.R., Martin A.J., Dhillon H., Davis I.D., Chi K.N., Chowdhury S., Horvath L.G., Lawrence N.J., and Marx G.M.
- Abstract
Background: We previously reported that treatment with enzalutamide (ENZA) rather than an older non-steroidal anti-androgen (NSAA: bicalutamide, nilutamide, or flutamide), resulted in longer overall survival when added to standard first-line treatment, with or without concurrent early docetaxel, in mHSPC (hazard ratio 0.67, 95% CI 0.52 to 0.86, p = 0.002, NEJM 2019). Here we report effects on HRQL. Method(s): HRQL was measured with the EORTC QLQ-C30 and PR25 at weeks 0, 4, 12, and then 12-weekly until clinical progression. We used mixed models for repeated measures to calculate the least squares mean difference (LSMD), 95% CI, and p-value for comparisons of the randomly assigned groups for all assessments from week 4 to 156. For each analysis of deterioration-free survival, the endpoint was defined a-priori as the earliest of death, clinical progression, cessation of study treatment, or a 10-point worsening from baseline (minimum clinically important difference on scales scored from 0 to 100) in the pertinent HRQL sub-scale: physical functioning (PF), global health and quality of life (GHQL), cognitive functioning (CF), and fatigue; p-values were based on the log-rank test. Result(s): Completion of HRQL forms in 1016 men with a baseline assessment of HRQL (1125 randomised) ranged from 94% at week 12 to 78% at week 156. Random assignment to ENZA v NSAA was associated with modest impairments (LSMD, 95% CI) from week 4 to 156 in fatigue (5.0, 3.3 to 6.7, p < 0.0001), CF (3.9, 2.4 to 5.4, p < 0.0001), and PF (2.5, 1.2 to 3.8, p = 0.0002), but not GHQL (1.1, -0.4 to 2.6, p = 0.16). Deterioration-free survival rates at 3 years favoured ENZA over NSAA for GHQL (32% v 18%, p < 0.0001), CF (33% v 21%, p = 0.0003), and PF (31% v 22%, p = 0.001), but not fatigue (26% v 18%, p = 0.1). The effects of ENZA on HRQL were relatively stable over time and unaffected by treatment with concurrent early docetaxel. Conclusion(s): The addition of ENZA maintained GHQL and improved deteriora
- Published
- 2020
115. Health-related quality of life (HRQL) in a randomized phase III trial of enzalutamide with standard first-line therapy for metastatic, hormone-sensitive prostate cancer (mHSPC): ENZAMET (ANZUP 1304), an ANZUP-led, international, co-operative group trial.
- Author
-
Thomson A., Sandhu S.K., Tan T.H., Zielinski R., Sweeney C.J., Stockler M.R., Martin A.J., Dhillon H., Davis I.D., Chi K.N., Chowdhury S., Horvath L.G., Lawrence N.J., Marx G.M., Mc Caffrey J., Mc Dermott R., North S.A., Parnis F., Pook D.W., Reaume M.N., Thomson A., Sandhu S.K., Tan T.H., Zielinski R., Sweeney C.J., Stockler M.R., Martin A.J., Dhillon H., Davis I.D., Chi K.N., Chowdhury S., Horvath L.G., Lawrence N.J., Marx G.M., Mc Caffrey J., Mc Dermott R., North S.A., Parnis F., Pook D.W., and Reaume M.N.
- Abstract
Background: We previously reported that treatment with enzalutamide (ENZA) rather than an older non-steroidal anti-androgen (NSAA: bicalutamide, nilutamide, or flutamide), resulted in longer overall survival when added to standard first-line treatment, with or without concurrent early docetaxel, in mHSPC (hazard ratio 0.67, 95% CI 0.52 to 0.86, p=0.002, NEJM 2019). Here we report effects on HRQL. Method(s): HRQL was measured with the EORTC QLQ-C30 and PR25 at weeks 0, 4, 12, and then 12-weekly until clinical progression. We used mixed models for repeated measures to calculate the least squares mean difference (LSMD), 95% CI, and p-value for comparisons of the randomly assigned groups for all assessments from week 4 to 156. For each analysis of deterioration-free survival, the endpoint was defined a-priori as the earliest of death, clinical progression, cessation of study treatment, or a 10-point worsening from baseline (minimum clinically important difference on scales scored from 0 to 100) in the pertinent HRQL sub-scale: physical functioning (PF), global health and quality of life (GHQL), cognitive functioning (CF), and fatigue; p-values were based on the log-rank test. Result(s): Completion of HRQL forms in 1016 men with a baseline assessment of HRQL (1125 randomised) ranged from 94% at week 12 to 78% at week 156. Random assignment to ENZA v NSAA was associated with modest impairments (LSMD, 95% CI) from week 4 to 156 in fatigue (5.0, 3.3 to 6.7, p<0.0001), CF (3.9, 2.4 to 5.4, p<0.0001), and PF (2.5, 1.2 to 3.8, p=0.0002), but not GHQL (1.1,-0.4 to 2.6, p=0.16). Deterioration-free survival rates at 3 years favoured ENZA over NSAA for GHQL (32% v 18%, p<0.0001), CF (33% v 21%, p=0.0003), and PF (31% v 22%, p=0.001), but not fatigue (26% v 18%, p=0.1). The effects of ENZA on HRQL were relatively stable over time and unaffected by treatment with concurrent early docetaxel. Conclusion(s): The addition of ENZA maintained GHQL and improved deteriorationfree survival b
- Published
- 2020
116. The hydrogeochemistry of argillaceous rock formations at the Horonobe URL site, Japan
- Author
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Hama, K., Kunimaru, T., Metcalfe, R., and Martin, A.J.
- Published
- 2007
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117. Distinguishing between natural and aquaculture-derived sediment concentrations of heavy metals in the Broughton Archipelago, British Columbia
- Author
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Sutherland, T.F., Petersen, S.A., Levings, C.D., and Martin, A.J.
- Published
- 2007
- Full Text
- View/download PDF
118. Acceptance tests and criteria of the ATLAS transition radiation tracker
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Cwetanski, P., Akesson, T., Anghinolfi, F., Arik, E., Baker, O.K., Banas, E., Baron, S., Benjamin, D., Bertelsen, H., Bondarenko, V., Bytchkov, V., Callahan, J., Capeans, M., Cardiel-Sas, L., Catinaccio, A., Cetin, S.A., Chandler, J.T., Dam, M., Danielsson, H., Dittus, F., Dolgoshein, B., Dressnandt, N., Ebenstein, W.L., Eerola, P., Egorov, K., Farthouat, P., Fedin, O., Froidevaux, D., Gagnon, P., Gay, C., Ghodbane, N., Grichkevitch, Y., Grigalashvili, N., Grognuz, J., Hajduk, Z., Hansen, P., Katunin, S., Kayumov, F., Keener, P.T., Kekelidze, G., Khristatchev, A., Kittelmann, T., Konovalov, S., Koudine, L., Kovalenko, S., Kowalski, T., Kramarenko, V.A., Kruger, K., Laritchev, A., LeGeyt, B.C., Lichard, P., Luehring, F., Lundberg, B., Mackeprang, R., Maleev, V., Markina, I., Martin, A.J., McFarlane, K.W., Mialkowski, V., Michine, S., Mindur, B., Mitsou, V.A., Mjornmark, U., Morozov, S., Munar, A., Muraviev, S., Nadtochy, A., Nesterov, S., Newcomer, F.M., Nikitine, N., Ogren, H., Oh, S.H., Oleshko, S., Olszowska, J., Patritchev, S., Peshekhonov, V., Petti, R., Price, M., Rembser, C., Rohne, O., Romaniouk, A., Rust, D.R., Ryabov, Y., Ryjov, V., Schegelsky, V., Schmidt, M.P., Seliverstov, D., Shin, T., Shmeleva, A., Smirnov, S., Sosnovtsev, V., Soutchkov, S., Sprachmann, G., Tikhomirov, V., Van Berg, R., Vassilakopoulos, V.I., Vassilieva, L., Wang, C., Williams, H.H., Zalite, A., and Zalite, Y.
- Subjects
Gas-detectors -- Research ,Nuclear physics -- Research ,Nuclear radiation -- Research ,Nuclear radiation -- Measurement ,Business ,Electronics ,Electronics and electrical industries - Abstract
The Transition Radiation Tracker (TRT) sits at the outermost part of the ATLAS Inner Detector, encasing the Pixel Detector and the Semi-Conductor Tracker (SCT). The TRT combines charged particle track reconstruction with electron identification capability. This is achieved by layers of xenonfilled straw tubes with periodic radiator foils or fibers providing TR photon emission. The design and choice of materials have been optimized to cope with the harsh operating conditions at the LHC, which are expected to lead to an accumulated radiation dose of 10 Mrad and a neutron fluence of up to 2 x [10.sup.14] n/[cm.sup.2] after ten years of operation. The TRT comprises a barrel containing 52 000 axial straws and two end-cap parts with 320 000 radial straws. The total of 420 000 electronic channels (two channels per barrel straw) allows continuous tracking with many projective measurements (more than 30 straw hits per track). The assembly of the barrel modules in the US has recently been completed, while the end-cap wheel construction in Russia has reached the 50% mark. After testing at the production sites and shipment to CERN, all modules and wheels undergo a series of quality and conformity measurements. These acceptance tests survey dimensions, wire tension, gas-tightness, high-voltage stability and gas-gain uniformity along each individual straw. This paper gives details on the acceptance criteria and measurement methods. An overview of the most important results obtained to-date is also given. Index Terms--Acceptance criteria, gas detectors, quality control, straw tubes, tracking, transition radiation.
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- 2005
119. New light on the age of the White Nile
- Author
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Williams, Martin A.J., Adamson, Donald, Prescott, John R., and Williams, Frances M.
- Subjects
Geology -- Research ,Earth sciences - Abstract
Landsat 5 Thematic Mapper and 7 Enhanced Thematic Mapper imagery reveal lake shorelines in the White Nile valley as far south as lat 10[degrees]N. The highest shoreline is at 386 m elevation and was eroded when the White Nile formed a lake as wide as 70 km and >500 km long. Finely laminated green clays laid down on the floor of this lake are overlain by alluvial sands and clays, dated by optically stimulated lumisnescence as 15 ka to older than 250 ka. The alluvium was deposited during interglacial episodes of stronger summer monsoons and very high White Nile floods. The White Nile paleolake is much older than marine oxygen isotope stage 7 and may have formed ca. 400 ka, during the exceptionally long stage 11 interglacial. Keywords: Quaternary, Nile, paleohydrology, luminescence dating, paleolake.
- Published
- 2003
120. The Relationship between Asthma Severity, Family Functioning and the Health-Related Quality of Life of Children with Asthma
- Author
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Sawyer, M.G., Spurrier, N., Whaites, L., Kennedy, D., Martin, A.J., and Baghurst, P.
- Published
- 2000
- Full Text
- View/download PDF
121. Intron-mediated gusA expression in tritordeum and wheat resulting from particle bombardment
- Author
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Salgueiro, Sancha, Pignocchi, Cristina, and Parry, Martin A.J.
- Published
- 2000
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122. Sensors and computing systems in smart clothing
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Martin, A.J., primary
- Published
- 2009
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- View/download PDF
123. Late Quaternary Environments in the Nile Basin
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Williams, Martin A.J., primary and Talbot, Michael R., additional
- Published
- 2009
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- View/download PDF
124. Cenozoic Evolution of the Nile Basin
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Talbot, Michael R., primary and Williams, Martin A.J., additional
- Published
- 2009
- Full Text
- View/download PDF
125. Elucidating the biosynthesis of 2-carboxyarabinitol 1-phosphate through reduced expression of chloroplastic fructose 1,6-bisphosphate phosphatase and radiotracer studies with [sup.14]C[0.sub.2]
- Author
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Andralojc, P. John, Keys, Alfred J., Kossmann, Jens, and Parry, Martin A.J.
- Subjects
Photosynthesis research -- Analysis ,Chloroplasts -- Research ,Biosynthesis -- Research ,Science and technology - Abstract
2-Carboxyarabinitol 1-phosphate limits photosynthetic C[O.sub.2] assimilation at low light because it is a potent, naturally occurring inhibitor of ribulose 1,5-bisphosphate carboxylase/oxygenase. Evidence is presented that this inhibitor is derived from chloroplastic fructose 1,6-bisphosphate. First, transgenic plants containing decreased amounts of chloroplastic fructose 1,6-bisphosphate phosphatase contained increased amounts of fructose 1,6-bisphosphate and 2-carboxyarabinitol 1-phosphate and greatly increased amounts of the putative intermediates hamamelose and 2-carboxyarabinitol, which in some cases were as abundant as sucrose. Second, French bean leaves in the light were shown to incorporate [sup.14]C from [sup.14]C[O.sub.2] sequentially into fructose 1,6-bisphosphate, hamamelose bisphosphate, hamamelose monophosphate, hamamelose, and 2-carboxyarabinitol. As shown previously, [sup.14]C assimilated by photosynthesis was also incorporated into 2-carboxyarabinitol 1-phosphate during subsequent darkness.
- Published
- 2002
126. The Khartoum-Omdurman conurbation: a growing megacity at the confluence of the Blue and White Nile Rivers
- Author
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Zerboni, Andrea, primary, Brandolini, Filippo, additional, Mariani, Guido S., additional, Perego, Alessandro, additional, Salvatori, Sandro, additional, Usai, Donatella, additional, Pelfini, Manuela, additional, and Williams, Martin A.J., additional
- Published
- 2020
- Full Text
- View/download PDF
127. Guest Editorial: Special issue on low voltage low power integrated circuits and systems
- Author
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Khateb, F., primary, Kulej, T., additional, Ferreira, L.H.C., additional, and Lopez-Martin, A.J., additional
- Published
- 2020
- Full Text
- View/download PDF
128. Decrease in phosphoribulokinase activity by antisense RNA in transgenic tobacco. Relationship between photosynthesis, growth, and allocation at different nitrogen levels (1)
- Author
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Banks, Fiona M., Driscoll, Simon P., Parry, Martin A.J., Lawlor, David W., Knight, Jacqui S., Gray, John C., and Paul, Matthew J.
- Subjects
Growth (Plants) -- Genetic aspects ,Photosynthesis -- Research ,Tobacco (Plant) -- Genetic aspects ,Genetically modified plants -- Research ,Biological sciences ,Science and technology - Published
- 1999
129. Randomized phase II trial of carboplatin versus paclitaxel and carboplatin in platinum-sensitive recurrent advanced ovarian carcinoma: a GEICO (Grupo Español de Investigación en Cáncer de Ovario) study
- Author
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González-Martín, A.J., Calvo, E., Bover, I., Rubio, M.J., Arcusa, A., Casado, A., Ojeda, B., Balañá, C., Martínez, E., Herrero, A., Pardo, B., Adrover, E., Rifá, J., Godes, M.J., Moyano, A., and Cervantes, A.
- Published
- 2005
- Full Text
- View/download PDF
130. Beam tests of ATLAS SCT silicon strip detector modules
- Author
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Campabadal, F., Fleta, C., Key, M., Lozano, M., Martinez, C., Pellegrini, G., Rafi, J.M., Ullan, M., Johansen, L., Pommeresche, B., Stugu, B., Ciocio, A., Fadeyev, V., Gilchriese, M., Haber, C., Siegrist, J., Spieler, H., Vu, C., Bell, P.J., Charlton, D.G., Dowell, J.D., Gallop, B.J., Homer, R.J., Jovanovic, P., Mahout, G., McMahon, T.J., Wilson, J.A., Barr, A.J., Carter, J.R., Fromant, B.P., Goodrick, M.J., Hill, J.C., Lester, C.G., Palmer, M.J., Parker, M.A., Robinson, D., Sabetfakhri, A., Shaw, R.J., Anghinolfi, F., Chesi, E., Chouridou, S., Fortin, R., Grosse-Knetter, J., Gruwe, M., Ferrari, P., Jarron, P., Kaplon, J., Macpherson, A., Niinikoski, T., Pernegger, H., Roe, S., Rudge, A., Ruggiero, G., Wallny, R., Weilhammer, P., Bialas, W., Dabrowski, W., Grybos, P., Koperny, S., Blocki, J., Bruckman, P., Gadomski, S., Godlewski, J., Gornicki, E., Malecki, P., Moszczynski, A., Stanecka, E., Stodulski, M., Szczygiel, R., Turala, M., Wolter, M., Ahmad, A., Benes, J., Carpentieri, C., Feld, L., Ketterer, C., Ludwig, J., Meinhardt, J., Runge, K., Mikulec, B., Mangin-Brinet, M., D’Onofrio, M., Donega, M., Moêd, S., Sfyrla, A., Ferrere, D., Clark, A.G., Perrin, E., Weber, M., Bates, R.L., Cheplakov, A., Saxon, D.H., O’Shea, V., Smith, K.M., Iwata, Y., Ohsugi, T., Kohriki, T., Kondo, T., Terada, S., Ujiie, N., Ikegami, Y., Unno, Y., Takashima, R., Brodbeck, T., Chilingarov, A., Hughes, G., Ratoff, P., Sloan, T., Allport, P.P., Casse, G.-L., Greenall, A., Jackson, J.N., Jones, T.J., King, B.T., Maxfield, S.J., Smith, N.A., Sutcliffe, P., Vossebeld, J., Beck, G.A., Carter, A.A., Lloyd, S.L., Martin, A.J., Morris, J., Morin, J., Nagai, K., Pritchard, T.W., Anderson, B.E., Butterworth, J.M., Fraser, T.J., Jones, T.W., Lane, J.B., Postranecky, M., Warren, M.R.M., Cindro, V., Kramberger, G., Mandić, I., Mikuž, M., Duerdoth, I.P., Freestone, J., Foster, J.M., Ibbotson, M., Loebinger, F.K., Pater, J., Snow, S.W., Thompson, R.J., Atkinson, T.M., Bright, G., Kazi, S., Lindsay, S., Moorhead, G.F., Taylor, G.N., Bachindgagyan, G., Baranova, N., Karmanov, D., Merkine, M., Andricek, L., Bethke, S., Kudlaty, J., Lutz, G., Moser, H.-G., Nisius, R., Richter, R., Schieck, J., Cornelissen, T., Gorfine, G.W., Hartjes, F.G., Hessey, N.P., de Jong, P., Muijs, A.J.M., Peeters, S.J.M., Tomeda, Y., Tanaka, R., Nakano, I., Dorholt, O., Danielsen, K.M., Huse, T., Sandaker, H., Stapnes, S., Bargassaa, P., Reichold, A., Huffman, T., Nickerson, R., Weidberg, A., Doucas, G., Hawes, B., Lau, W., Howell, D., Kundu, N., Wastie, R., Bohm, J., Mikestikova, M., Stastny, J., Broklová, Z., Brož, J., Doležal, Z., Kodyš, P., Kubík, P., Řezníček, P., Vorobel, V., Wilhelm, I., Chren, D., Horazdovsky, T., Linhart, V., Pospisil, S., Sinor, M., Solar, M., Sopko, B., Stekl, I., Ardashev, E.N., Golovnya, S.N., Gorokhov, S.A., Kholodenko, A.G., Rudenko, R.E., Ryadovikov, V.N., Vorobiev, A.P., Adkin, P.J., Apsimon, R.J., Batchelor, L.E., Bizzell, J.P., Booker, P., Davis, V.R., Easton, J.M., Fowler, C., Gibson, M.D., Haywood, S.J., MacWaters, C., Matheson, J.P., Matson, R.M., McMahon, S.J., Morris, F.S., Morrissey, M., Murray, W.J., Phillips, P.W., Tyndel, M., Villani, E.G., Dorfan, D.E., Grillo, A.A., Rosenbaum, F., Sadrozinski, H.F.-W., Seiden, A., Spencer, E., Wilder, M., Booth, P., Buttar, C.M., Dawson, I., Dervan, P., Grigson, C., Harper, R., Moraes, A., Peak, L.S., Varvell, K.E., Chu, Ming-Lee, Hou, Li-Shing, Lee, Shih-Chang, Teng, Ping-Kun, Wan, Changchun, Hara, K., Kato, Y., Kuwano, T., Minagawa, M., Sengoku, H., Bingefors, N., Brenner, R., Ekelöf, T., Eklund, L., Bernabeu, J., Civera, J.V., Costa, M.J., Fuster, J., Garcia, C., Garcia, J.E., Gonzalez-Sevilla, S., Lacasta, C., Llosa, G., Marti-Garcia, S., Modesto, P., Sanchez, J., Sospedra, L., Vos, M., Fasching, D., Gonzalez, S., Jared, R.C., and Charles, E.
- Published
- 2005
- Full Text
- View/download PDF
131. Sleep-Disordered Breathing in Prader-Willi Syndrome and its Association with Neurobehavioral Abnormalities
- Author
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O'Donoghue, F.J., Camfferman, D., Kennedy, J.D., Martin, A.J., Couper, T., Lack, L.D., Lushington, K., and McEvoy, R.D.
- Published
- 2005
- Full Text
- View/download PDF
132. High-Tc ramp-type Josephson junctions on MgO substrates for terahertz applications
- Author
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Myoren, Hiroaki, Verhoeven, Martin A.J., Chen, Jian, Nakajima, Kensuke, Yamashita, Tsutomu, Blank, Dave H.A., and Rogalla, Horst
- Subjects
High temperature superconductors -- Usage ,Josephson junction -- Research ,Millimeter wave devices -- Research ,Business ,Electronics ,Electronics and electrical industries - Abstract
High temperature ramp-type superconductor junctions were produced using PrBa(sub 2)Cu(sub 3 - x)Ga(sub x)O(sub 7 - delta) (x = 0.1, 0.4) barriers on MgO substrates. The junctions had I-V curves with thermally and voltage activated conductivity similar to those of resistively shunted Josephson junctions. The maximum response of the junctions for 100-GHz millimeter-wave irradiation could be seen up to 12 mV corresponding to 6 THz.
- Published
- 1998
133. Characterization of ramp-type YBa2Cu3O7 junctions by AFM
- Author
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Blank, Dave H.A., Rijnmders, Guus J.H.M., Bergs, Roger M.H., Verhoeven, Martin A.J., and Rogalla, Horst
- Subjects
Josephson junction -- Research ,Thin films -- Research ,Atomic force microscopy -- Usage ,Business ,Electronics ,Electronics and electrical industries - Abstract
A study was conducted on the ramp morphology of REBa2Cu3O7 epitaxial films grown on SrTiO3 substrates. The films were developed using high resolution electron microscopy, atomic force microscopy, radio frequency magnetron sputter deposition and pulse laser deposition. Results show ramp surface crystallization and the creation of terraces and a non-homogeneous growth of the barrier material.
- Published
- 1997
134. A high-Tc 4-bit periodic threshold analog-to-digital converter
- Author
-
Gerritsma, Gerrit J., Verhoeven, Martin A.J., Wiegerink, Remco J., and Rogalla, Horst
- Subjects
Analog to digital converters -- Design and construction ,Josephson junction -- Usage ,Comparator circuits -- Research ,Business ,Electronics ,Electronics and electrical industries - Abstract
A 4-bit high temperature periodic threshold analog to digital converter was developed using ramp-type Josephson junctions. Practical design constraints involving switching speed, available technology, noise immunity and flux flow were identified. Efforts to enhance high temperature superconductor technology also led to the development of a basic comparator that is not affected by analog input signal-generated stray fields.
- Published
- 1997
135. Subsurface structure under a basaltic monogenetic volcano near the active Atera fault
- Author
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Tanaka, T., Aoki, H., Martin, A.J., Oshita, K., Nozaki, K., and Onishi, M.
- Published
- 2004
- Full Text
- View/download PDF
136. Magnetic characterization and variability study of the magnetic SPB star o Lupi
- Author
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Buysschaert, B., Neiner, C., Martin, A.J., Oksala, M.E., Aerts, C., Tkachenko, A., Alecian, E., Buysschaert, B., Neiner, C., Martin, A.J., Oksala, M.E., Aerts, C., Tkachenko, A., and Alecian, E.
- Abstract
Contains fulltext : 201094.pdf (preprint version ) (Open Access)
- Published
- 2019
137. Enzalutamide with standard first-line therapy in metastatic prostate cancer.
- Author
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North S.A., Frydenberg M., Hague W.E., Horvath L.G., Joshua A.M., Lawrence N.J., Marx G., McCaffrey J., McDermott R., McJannett M., Coskinas X., Parnis F., Parulekar W., Pook D.W., Neil Reaume M., Sandhu S.K., Tan A., Hsiang Tan T., Thomson A., Tu E., Vera-Badillo F., Williams S.G., Yip S., Zhang A.Y., Zielinski R.R., Sweeney C.J., Davis I.D., Martin A.J., Stockler M.R., Begbie S., Chi K.N., Chowdhury S., North S.A., Frydenberg M., Hague W.E., Horvath L.G., Joshua A.M., Lawrence N.J., Marx G., McCaffrey J., McDermott R., McJannett M., Coskinas X., Parnis F., Parulekar W., Pook D.W., Neil Reaume M., Sandhu S.K., Tan A., Hsiang Tan T., Thomson A., Tu E., Vera-Badillo F., Williams S.G., Yip S., Zhang A.Y., Zielinski R.R., Sweeney C.J., Davis I.D., Martin A.J., Stockler M.R., Begbie S., Chi K.N., and Chowdhury S.
- Abstract
BACKGROUND Enzalutamide, an androgen-receptor inhibitor, has been associated with improved overall survival in men with castration-resistant prostate cancer. It is not known whether adding enzalutamide to testosterone suppression, with or without early docetaxel, will improve survival in men with metastatic, hormone-sensitive prostate cancer. METHODS In this open-label, randomized, phase 3 trial, we assigned patients to receive testosterone suppression plus either open-label enzalutamide or a standard nonsteroidal antiandrogen therapy (standard-care group). The primary end point was overall survival. Secondary end points included progression-free survival as determined by the prostate-specific antigen (PSA) level, clinical progression-free survival, and adverse events. RESULTS A total of 1125 men underwent randomization; the median follow-up was 34 months. There were 102 deaths in the enzalutamide group and 143 deaths in the standard-care group (hazard ratio, 0.67; 95% confidence interval [CI], 0.52 to 0.86; P=0.002). Kaplan-Meier estimates of overall survival at 3 years were 80% (based on 94 events) in the enzalutamide group and 72% (based on 130 events) in the standard-care group. Better results with enzalutamide were also seen in PSA progression-free survival (174 and 333 events, respectively; hazard ratio, 0.39; P<0.001) and in clinical progression-free survival (167 and 320 events, respectively; hazard ratio, 0.40; P<0.001). Treatment discontinuation due to adverse events was more frequent in the enzalutamide group than in the standard-care group (33 events and 14 events, respectively). Fatigue was more common in the enzalutamide group; seizures occurred in 7 patients in the enzalutamide group (1%) and in no patients in the standard-care group. CONCLUSIONS Enzalutamide was associated with significantly longer progression-free and overall survival than standard care in men with metastatic, hormone-sensitive prostate cancer receiving testosterone suppression. The
- Published
- 2019
138. Patients' preferences for 3 months versus 6 months of adjuvant chemotherapy (ACT) for colon cancer in the SCOT trial: what survival benefits make longer chemotherapy worthwhile?.
- Author
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Goldstein D., Boadle D., Morris M.F., Tebbutt N.C., Aiken C., Paul J., Segelov E., Haydon A.M., Iveson T., Stockler M.R., Blinman P.L., Martin A.J., Jefford M., Goldstein D., Boadle D., Morris M.F., Tebbutt N.C., Aiken C., Paul J., Segelov E., Haydon A.M., Iveson T., Stockler M.R., Blinman P.L., Martin A.J., and Jefford M.
- Abstract
Background: The optimal duration of ACT following surgery for colon cancer remains controversial. SCOT is an international, randomised trial that compared 3 months versus 6 months of ACT in this setting. We sought the survival benefits that patients participating in SCOT judged necessary to make extra 3 months of ACT worthwhile. Method(s): SCOT participants from Australia & New Zealand completed a validated questionnaire 3 and 18 months after randomisation to elicit the minimum survival benefit each participant judged necessary to make it worthwhile having ACT for 6 months rather than 3 months. Standardised hypothetical scenarios used the following baseline survivals with 3 months of ACT: life expectancies (LE) of 5 years (5Y) and 15 years (15Y), and 5-year survival rates (5YS) of 65% and 85%. Comparisons were nonparametric, 2-sided, and considered statistically significant if p < 0.05. Result(s): Questionnaires were completed by 160 participants, 82 allocated 3 months ACT, and 78 allocated 6 months ACT. ACT was FOLFOX in 121 (75%), XELOX in 39 (25%), and the mean age was 64. Preferences varied substantially among participants, and did not differ according to the randomly allocated treatment group. The median survival benefits judged necessary to make the extra 3 months of ACT worthwhile were an extra: 3 years beyond a LE of 5Y; 3 years beyond a LE of 15Y; 15% beyond a 65% 5YS; and 5% beyond an 85% 5YS. Preferences were similar at 3 months and 18 months. Participants with symptomatic peripheral neuropathy (132, 82%) judged a median benefit of an extra 5% beyond a 65% 5YS necessary to warrant their symptoms. Conclusion(s): Participants' preferences varied substantially, and many judged much larger benefits needed to warrant having ACT for 6 months rather than 3 months than the estimates of the benefits based on the IDEA meta-analysis.
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- 2019
139. Overall survival (OS) results of a phase III randomized trial of standard-of-care therapy with or without enzalutamide for metastatic hormone-sensitive prostate cancer (mHSPC): ENZAMET (ANZUP 1304), an ANZUP-led international cooperative group trial.
- Author
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Sweeney C., Marx G.M., McCaffrey J., McDermott R., North S.A., Parnis F., Pook D.W., Reaume M.N., Sandhu S.K., Tan T.H., Thomson A., Zielinski R.R., Martin A.J., Davis I.D., Stockler M.R., Chi K.N., Chowdhury S., Frydenberg M., Horvath L., Lawrence N.J., Sweeney C., Marx G.M., McCaffrey J., McDermott R., North S.A., Parnis F., Pook D.W., Reaume M.N., Sandhu S.K., Tan T.H., Thomson A., Zielinski R.R., Martin A.J., Davis I.D., Stockler M.R., Chi K.N., Chowdhury S., Frydenberg M., Horvath L., and Lawrence N.J.
- Abstract
Background: Testosterone suppression (TS) is the backbone of treatment for mHSPC. OS is improved by the addition of early docetaxel (DOC) or abiraterone to TS. ENZAMET assessed the effects of enzalutamide (ENZA), a potent androgen receptor (AR) inhibitor, versus a nonsteroidal anti-androgen (NSAA: bicalutamide, nilutamide, or flutamide) in addition to SOC (TS with or without DOC) in mHSPC. Method(s): Men with mHSPC were randomly assigned 1:1 to receive TS plus either ENZA or NSAA. Randomization was stratified by: volume of disease (high vs low, according to CHAARTED); planned early DOC; planned anti-resorptive therapy, comorbidity score (ACE-27), and study site. The primary endpoint was overall survival. Accrual of 1100 men provided 80% power to detect a 25% reduction in the hazard of death (HR 0.75) with up to 4 interim analyses (IA), the first planned to occur after 235 deaths (50% of total information with a critical p-value threshold <0.0031 by the Lan-DeMets alpha-spending approach with O'Brien-Fleming type shape). Subgroup analyses to assess possible modulation of the treatment effect were specified a priori and included planned early docetaxel (yes vs no) and volume of disease (high vs low). Result(s): We randomly assigned 1125 patients from 31MAR14 to 24MAR17. The treatment groups were well balanced for all important baseline factors. Criteria for early reporting were met at the first IA (28FEB2019) after a median follow-up of 33 months. Overall survival was prolonged by ENZA (see below). At 3 years, 36% NSAA vs 64% ENZA were still on their assigned study treatment. Serious adverse events (regardless of attribution) within 30 days of study treatment occurred in 42% ENZA vs 34% NSAA, commensurate with the different durations of study treatment. Conclusion(s): ENZA significantly improved OS when added to SOC in mHSPC. The benefits appeared lower in those planned to receive early DOC. Results of analyses with updated follow-up triggered by this IA will be prese
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- 2019
140. The Khartoum-Omdurman conurbation: a growing megacity at the confluence of the Blue and White Nile Rivers.
- Author
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Zerboni, Andrea, Brandolini, Filippo, Mariani, Guido S., Perego, Alessandro, Salvatori, Sandro, Usai, Donatella, Pelfini, Manuela, and Williams, Martin A.J.
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METROPOLITAN areas ,MEGALOPOLIS ,URBAN planning ,URBAN growth ,AGRICULTURAL development ,ARCHAEOLOGICAL excavations ,HUMAN settlements - Abstract
Khartoum is one of the largest cities in Africa, located immediately south of the junction of the Blue and White Nile rivers in central Sudan. The growth of the Greater Khartoum-Omdurman conurbation arose – without a proper urban plan – from the agricultural wealth created through the completion of three dams, and mostly in the last three decades. Urban expansion was enabled by and helped to enhance the major agricultural expansion of the Gezira clay plains located to the south between the lower Blue and White Nile rivers. The region has been a focus of human settlement for at least 8,000 years, initially by semi-sedentary groups with a fishing-hunting-gathering lifestyle and later by Neolithic groups as shown by hundreds of archaeological sites. Today, Khartoum is a desert city, still very vulnerable to floods triggered by intense convectional storms. Such extreme events may become more common in future, representing a major geomorphological hazard. Moreover, uncontrolled urban and agricultural development is threatening most of the cultural heritage of the region. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
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141. An HTS quasi-one junction SQUID-based periodic threshold comparator for a 4-bit superconductive flash A D converter
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Wiegerink, Remco J., Gerritsma, Gerrit J., Reuvekamp, Eugene M.C.M., Verhoeven, Martin A.J., and Rogalla, Horst
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Superconducting quantum interference devices -- Research ,High temperature superconductors -- Usage ,Comparator circuits -- Design and construction ,Business ,Electronics ,Electronics and electrical industries - Abstract
Testing of an all-high temperature superconductor periodic threshold comparator designed for a 4-bit A D converter shows that the threshold curves have excess periods than needed for the converter. The current design indicates that the threshold curve is also directly regulated by the analog input current. The effect of flux flow and the thermal noise immunity on the design of Josephson junction for the comparator circuit are discussed.
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- 1995
142. Ramp type HTS Josephson junctions with PrBaCuGaO barriers
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Verhoeven, Martin A.J., Gerritsma, Gerrit J., Rogalla, Horst, and Golubov, Alexander A.
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Flux pinning -- Research ,Josephson junction -- Research ,Superconductive devices -- Research ,Business ,Electronics ,Electronics and electrical industries - Abstract
DyBa2Cu3O7-delta and PrBa2Cu3-xGaxO7-delta are used as electrode material and junction barriers, respectively, in the fabrication of ramp type Josephson junctions. The junctions are subsequently investigated for their voltage-current characteristics at varying temperatures using standard electrical measurements. Results show that the junctions deviate from the ideal Fraunhofer pattern due to flux trapping.
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- 1995
143. EP08.02-070 High Incidence of Peridiagnosis Thromboembolic Events In Patients with BRAF Mutant Lung Cancer
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Aparicio Salcedo, I., Iranzo Gómez, P., Reyes, R., Bote de Cabo, H., Saigi Morgui, M., Bringas Beranek, M., Bosch-Barrera, J., Corral Jaime, J., Aparisi Aparisi, F., Ruffinelli Rodríguez, J.C., Jiménez Munarríz, B., Lage Alfranca, Y., Lopez-Castro, R., Majem Tarruella, M., Vázquez Estevez, S., Artal Cortés, Á., Rodríguez-Pérez, Á.R., Lázaro Quintela, M., Sánchez Torres, J.M., Reguart Aransay, N., Cucurull Salamero, M., Gil-Bazo, I., Camps Herrero, C., Nadal Alforja, E., del Barrio Díaz Aldagalan, A., Garrido López, P., Dómine Gómez, M., Álvarez Álvarez, R., Muñoz Martín, A.J., and Calles Blanco, A.
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- 2022
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144. Comparison of a lattice Boltzmann simulation of steep internal waves and laboratory measurements using particle image velocimetry
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Buick, J.M., Martin, A.J., Cosgrove, J.A., Greated, C.A., and Easson, W.J.
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- 2003
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145. The mobility of radium-226 and trace metals in pre-oxidized subaqueous uranium mill tailings
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Martin, A.J, Crusius, J, Jay McNee, J, and Yanful, E.K
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- 2003
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146. PV Beyond Electricity, Heat Pumps Hybridization for a Multiplicative Effect towards NZEB
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Sanz Martinez, A., Fuente Dacal, R., Martin, A.J., Hermoso, N., and Vega De Seoane, J.M.
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PV Systems - Performance, Applications and Integration ,Grid and Energy System Integration - Abstract
35th European Photovoltaic Solar Energy Conference and Exhibition; 1848-1854, The high energy consuming building sector needs to meet both electricity and heat demands. In a NZEB scenario most of the consumed energy would be generated locally by means of RES that nowadays seem not to provide an attractive cost-competitiveness. Solar based technologies tend to be the most promising ones, but for high densely populated and restricted areas buildings thermal loads are still a major setback concerning zero energy performance. Traditional fossil fuel or single renewable approaches will not be valid from efficiency and/or cost competitiveness. PV seem to have a great future as the build-environment local generation technology, but high capacity scenarios related grid impact is still a serious threat for massive deployment. HPs are an efficient approach for a reduction of building thermal comfort related CO2 emission and capable of using the electrical infrastructure as back-up source. Therefore, if both technologies are individually suitable, merging them in a unique solution should enable even higher benefits. The current work is focused on the potential analysis of PV and smart combination with HP as entire-lifetime feasible solutions for NZEB. The techno-economic analysis is focused on an 80s residential-use 95-dwelling building, located at 6 different EU sites for a set of 5 scenarios, combining market standard natural gas boilers, conventional HPs and PV systems. The results show that the proposed solution could be a currently efficient, renewable and cost-competitive.
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- 2018
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147. Hybrid Cyanobacterial-Tobacco Rubisco Supports Autotrophic Growth and Procarboxysomal Aggregation
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Orr, Douglas J., primary, Worrall, Dawn, additional, Lin, Myat T., additional, Carmo-Silva, Elizabete, additional, Hanson, Maureen R., additional, and Parry, Martin A.J., additional
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- 2019
- Full Text
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148. Health-related quality of life (HRQL) in a randomized phase III trial of enzalutamide with standard first-line therapy for metastatic, hormone-sensitive prostate cancer (mHSPC): ENZAMET (ANZUP 1304), an ANZUP-led, international, co-operative group trial
- Author
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Stockler, M.R., primary, Martin, A.J., additional, Dhillon, H., additional, Davis, I.D., additional, Chi, K.N., additional, Chowdhury, S., additional, Horvath, L.G., additional, Lawrence, N.J., additional, Marx, G.M., additional, Caffrey, J Mc, additional, McDermott, R., additional, North, S.A., additional, Parnis, F., additional, Pook, D.W., additional, Reaume, M.N., additional, Sandhu, S.K., additional, Tan, T.H., additional, Thomson, A., additional, Zielinski, R., additional, and Sweeney, C.J., additional
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- 2019
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149. Assumptions, damn assumptions and statistics
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Simes, R.J., primary and Martin, A.J., additional
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- 2019
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150. Overexpression of ca1pase Decreases Rubisco Abundance and Grain Yield in Wheat
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Lobo, Ana Karla M., primary, Orr, Douglas J., additional, Gutierrez, Marta Oñate, additional, Andralojc, P. John, additional, Sparks, Caroline, additional, Parry, Martin A.J., additional, and Carmo-Silva, Elizabete, additional
- Published
- 2019
- Full Text
- View/download PDF
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