500 results on '"Mollapour, Mehdi"'
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102. Faculty Opinions recommendation of A methylated lysine is a switch point for conformational communication in the chaperone Hsp90.
103. Structural and functional regulation of lactate dehydrogenase-A in cancer
104. Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol
105. Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex
106. Overexpressed Sod1p acts either to reduce or to increase the lifespans and stress resistance of yeast, depending on whether it is Cu2+-deficient or an active Cu,Zn-superoxide dismutase
107. Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast
108. Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants
109. Mnsod overexpression extends the yeast chronological (G0) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells
110. The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells
111. The ZbYME2 gene from the food spoilage yeast Zygosaccharomyces bailii confers not only YME2 functions in Saccharomyces cerevisiae, but also the capacity for catabolism of sorbate and benzoate, two major weak organic acid preservatives
112. Mnsod overexpression extends the yeast chronological (G 0) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells
113. Design of Disruptors of the Hsp90–Cdc37 Interface
114. Faculty Opinions recommendation of Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress.
115. Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity
116. Faculty Opinions recommendation of A PQM-1-Mediated Response Triggers Transcellular Chaperone Signaling and Regulates Organismal Proteostasis.
117. MP05-16 TSC1 EXPRESSION AS A PREDICTIVE BIOMARKER OF BLADDER CANCER RESPONSE TO HSP90 INHIBITORS
118. Activation of the ATPase Activity of Hsp90 by the Stress-Regulated Cochaperone Aha1
119. Carcinomas of the renal medulla: A comprehensive genomic profiling (CGP) study.
120. Sporadic renal angiomyolipoma in a patient with Birt-Hogg-Dubé: chaperones in pathogenesis
121. PD46-11 PHOSPHORYLATION AND UBIQUITINATION REGULATE PROTEIN PHOSPHATASE-5 ACTIVITY AND ITS PROSURVIVAL ROLE IN KIDNEY CANCER
122. PD46-02 CARCINOMAS OF THE RENAL MEDULLA: A COMPREHENSIVE GENOMIC PROFILING (CGP) STUDY
123. MP88-13 TUMOR SUPPRESSOR TSC1 IS A NEW HSP90 COCHAPERONE THAT FACILITATES FOLDING OF KINASE AND NON-KINASE CLIENTS
124. 56 - Heat Shock Protein 90 and the Proteasome: Housekeeping Proteins That Are Also Molecular Targets for Cancer Therapy
125. Extracellular HSP90 warms up integrins for an irisin workout
126. Faculty Opinions recommendation of Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.
127. Faculty Opinions recommendation of Ubiquitination and regulation of AURKA identifies a hypoxia-independent E3 ligase activity of VHL.
128. Targeting Hsp90 in Non-Cancerous Maladies
129. The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
130. MP85-13 FNIP CO-CHAPERONES PROTECT THE TUMOR SUPPRESSOR FLCN FROM UBIQUITINATION AND DEGRADATION IN THE PROTEASOME
131. Sixth BHD Symposium and First International Upstate Kidney Cancer Symposium: latest scientific and clinical discoveries
132. The dynamic interactome of human Aha1 upon Y223 phosphorylation
133. Targeting Hsp90 in urothelial carcinoma
134. Efficacy of the Hsp90 Inhibitors in Prostate Cancer Therapy
135. The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
136. Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function
137. Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain
138. Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1 alpha stabilization by glucose-dependent generation of reactive oxygen species.
139. The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
140. Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors
141. Faculty Opinions recommendation of Differential requirements of Hsp90 and DNA for the formation of estrogen receptor homodimers and heterodimers.
142. Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells
143. Faculty Opinions recommendation of Single methyl group determines prion propagation and protein degradation activities of yeast heat shock protein (Hsp)-70 chaperones Ssa1p and Ssa2p.
144. Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer
145. PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
146. Activity of the yeast zinc-finger transcription factor War1 is lost with alanine mutation of two putative phosphorylation sites in the activation domain
147. Faculty Opinions recommendation of The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.
148. Faculty Opinions recommendation of Hsp90 and mitochondrial proteases Yme1 and Yta10/12 participate in ATP synthase assembly in Saccharomyces cerevisiae.
149. Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity
150. Faculty Opinions recommendation of Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells.
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