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493 results on '"Onimaru, Manabu"'

106. Tu1994 IN-VIVO DIAGNOSIS OF EARLY GASTRIC CANCER WITH FOURTH-GENERATION ENDOCYTOSCOPY AND THE NEWLY-RECOGNIZED "ENLARGED NUCLEAR SIGN"

Author

Angeli Abad, Mary Raina, primary, Shimamura, Yuto, additional, Rodriguez de Santiago, Enrique, additional, Manolakis, Anastassios C., additional, Fujiyoshi, Yusuke, additional, Sumi, Kazuya, additional, Sharma, Ashish, additional, Ikeda, Haruo, additional, Onimaru, Manabu, additional, and Inoue, Haruhiro, additional

Published
2019
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107. Sa1270 A NEWLY DEVELOPED DIAGNOSTIC TOOL FOR GERD AND NERD: ENDOSCOPIC PRESSURE STUDY INTEGRATED SYSTEM (EPSIS)

Author

Shimamura, Yuto, primary, Manolakis, Anastassios C., additional, Rodriguez de Santiago, Enrique, additional, Kobayashi, Yasutoshi, additional, Ominami, Masaki, additional, Fujiyoshi, Yusuke, additional, Fukuda, Hisashi, additional, Tomida, Hideomi, additional, Sumi, Kazuya, additional, Iwaya, Yugo, additional, Ikeda, Haruo, additional, Onimaru, Manabu, additional, and Inoue, Haruhiro, additional

Published
2019
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108. Peroral endoscopic myotomy (POEM) for complex achalasia and the POEM difficulty score

Author

Bechara, Robert, primary, Woo, Matthew, additional, Hookey, Lawrence, additional, Chung, Wiley, additional, Grimes, Kevin, additional, Ikeda, Haruo, additional, Onimaru, Manabu, additional, Sumi, Kazuya, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Maruyama, Shota, additional, Gomi, Kuniyo, additional, Shimamura, Yuto, additional, and Inoue, Haruhiro, additional

Published
2019
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109. Clinicopathological characteristics and treatment strategies in early gastric cancer: a retrospective cohort study

Author

Ito Hiroaki, Inoue Haruhiro, Ikeda Haruo, Onimaru Manabu, Yoshida Akira, Hosoya Toshihisa, Sudo Kosuke, Eleftheriadis Nikolas, Maselli Roberta, Maeda Chiyo, Wada Yoko, Sando Norimasa, Hamatani Shigeharu, and Kudo Shin-ei

Subjects
early gastric cancer, lymph node metastasis, endoscopic submucosal dissection, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background Both endoscopic and surgical approaches are employed in the treatment of early gastric cancer (EGC). The aim of this study was to establish appropriate treatment strategies for early gastric cancer. Methods We retrospectively examined clinicopathological data of EGC patients who had undergone surgery. Results A total of 327 patients (204 males and 123 females, mean age 63.2 years) were eligible for inclusion in the study. The median follow-up period was 31 months. Of 161 mucosal (pT1a) tumors, 87 were mainly undifferentiated and 110 had an undifferentiated component. Four patients with pT1a tumors had lymph node metastases; all these tumors were signet-ring cell carcinomas and were macroscopic type 0-IIc with ulceration, and only one of them had lymphatic invasion. Among patients with submucosal tumors, four of 43 patients with pT1b1 tumors and 37 of 123 patients with pT1b2 tumors had nodal metastases. Lymph node metastases were significantly higher in mixed undifferentiated type group than differentiated type group for both groups, pT1a-pT1b1 (p = 0.0251) and pT1b2 (p = 0.0430) subgroups. Only four of 45 patients with nodal metastases were diagnosed preoperatively by computed tomography (sensitivity 8.9%, specificity 96.2%). Nine patients with pT1b tumors had recurrence after surgery, and died. The sites of initial recurrence were liver, bone, peritoneum, distant nodes, and the surgical anastomosis. Conclusions The incidence of nodal metastases was approximately 5% in undifferentiated type mucosal (pT1a) tumors, and higher in submucosal (pT1b) tumors. The sensitivity of preoperative diagnosis of nodal metastases in EGC using computed tomography was relatively low in this study. Therefore at present surgery with adequate lymphadenectomy should be performed as curative treatment for undifferentiated type EGC.

Published
2011
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110. Characterization of intragastric pressure waveform in endoscopic pressure study integrated system: Novel diagnostic device for gastroesophageal reflux disease.

Author

Shimamura, Yuto, Inoue, Haruhiro, Rodriguez de Santiago, Enrique, Abad, Mary Raina Angeli, Fujiyoshi, Yusuke, Toshimori, Akiko, Tanabe, Mayo, Sumi, Kazuya, Iwaya, Yugo, Ikeda, Haruo, and Onimaru, Manabu

Subjects
GASTROESOPHAGEAL reflux, ESOPHAGOGASTRIC junction, REFERENCE values, SYMPTOMS, DIAGNOSIS
Abstract

Objectives: Endoscopic pressure study integrated system (EPSIS) is a novel diagnostic tool for gastroesophageal reflux disease (GERD). EPSIS has been developed to evaluate lower esophageal sphincter function by monitoring the intragastric pressure (IGP) while insufflating the stomach during gastroscopy. Based on previous data, EPSIS could diagnose GERD with good accuracy by assessing IGP waveform pattern. This study aimed to further characterize the waveform to improve the diagnostic yield of EPSIS. Methods: We conducted a retrospective analysis of patients with typical GERD symptoms who underwent both EPSIS and 24‐h impedance‐pH monitoring (MII‐pH) at a single tertiary referral center from October 2018 to May 2020. EPSIS was performed by using a through‐the‐scope catheter connected to the pressure measuring system (TR‐W550, TR‐TeH08, AP‐C35; Keyence, Osaka, Japan) to monitor IGP. Abnormal acid reflux was defined as acid exposure time (AET) over 6.0%. Pressure waveform was characterized as follows: (i) Basal IGP, (ii) Maximum IGP, (iii) Pressure difference, (iv) Gradient of the waveform. Results: A total of 57 patients with GERD symptoms were analyzed. Twenty‐one patients presented abnormal AET on MII‐pH. Among EPSIS parameters, pressure difference during insufflation correlated with AET (ρ = −0.66, P < 0.01) and showed the best diagnostic accuracy for AET with the cutoff value of 4.7 mmHg (area under the curve [AUC], 0.87). The gradient of EPSIS waveform also revealed good diagnostic accuracy for abnormal AET with the cutoff value of 0.07 mmHg/s (AUC, 0.81). Conclusions: Endoscopic pressure study integrated system waveform parameters, especially pressure difference, presented high diagnostic accuracy for the presence of abnormal acid reflux. [ABSTRACT FROM AUTHOR]

Published
2021
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111. RETRACTED: Long-term outcomes of per-oral endoscopic myotomy in patients with achalasia with a minimum follow-up of 2 years: an international multicenter study

Author

Ngamruengphong, Saowanee, Inoue, Haruhiro, Chiu, Philip Wai-Yan, Yip, Hon Chi, Bapaye, Amol, Ujiki, Michael, Patel, Lava, Desai, Pankaj N., Hayee, Bu, Haji, Amyn, Wong, Vivien Wai-yin, Perretta, Silvana, Dorwat, Shivangi, Pioche, Mathieu, Roman, Sabine, Rivory, Jérôme, Mion, François, Ponchon, Thierry, Garros, Aurélien, Nakamura, Jun, Hata, Yoshitaka, Balassone, Valerio, Onimaru, Manabu, Hajiyeva, Gulara, Ismail, Amr, Chen, Yen-I, Bukhari, Majidah, Haito-Chavez, Yamile, Kumbhari, Vivek, Maselli, Roberta, Repici, Alessandro, and Khashab, Mouen A.

Published
2017
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112. Importance of second‐look endoscopy after per‐oral endoscopic myotomy for safe postoperative management.

Author

Fujiyoshi, Yusuke, Inoue, Haruhiro, Abad, Mary Raina Angeli, Rodriguez de Santiago, Enrique, Nishikawa, Yohei, Sakaguchi, Takuki, Toshimori, Akiko, Shimamura, Yuto, Tanabe, Mayo, Sumi, Kazuya, Kimura, Ryusuke, Izawa, Shinya, Ikeda, Haruo, and Onimaru, Manabu

Subjects
ESOPHAGEAL motility disorders, ENDOSCOPY, ESOPHAGEAL achalasia, ESOPHAGEAL motility, RHINORRHEA, MYOTOMY
Abstract

Objectives: Per‐oral endoscopic myotomy (POEM) is a safe and effective treatment for achalasia and esophageal motility disorders. The role of second‐look endoscopy (SE) on postoperative day 1 has not been examined. This study aimed to evaluate the findings and need of SE after POEM. Methods: This is a single‐center, retrospective study. All consecutive patients who underwent POEM and SE on postoperative day 1 between December 2017 and September 2019 were included. The primary endpoint was the rate of newly‐detected adverse events (nAE) during SE that required endoscopic intervention or deviation from the normal postoperative course. Multivariate logistic regression was used to identify predictors of nAE. Results: Four‐hundred‐ninety‐seven patients (mean age, 50.3 years; female, 49.9%) were included. SE identified abnormal findings in a total of 71 patients (14.3%). nAE which required endoscopic intervention or deviation from the normal postoperative course were identified in 12 patients (2.4%): eight (1.6%) entry site dehiscence; two (0.4%) submucosal hemorrhage or hematoma; and two (0.4%) dehiscence of an intraoperative perforation site after endoclip closure. Other findings such as mucosal thermal damage without perforation and small submucosal hematoma were found in 54 patients (10.9%) and five patients (1.0%), respectively. Multivariate analysis showed that longer operation time and intraoperative adverse events (AE) were associated with clinically significant nAE during SE. Conclusions: Second‐look endoscopy can detect and treat nAE that may lead to severe AE. Thus, SE should be highly considered before starting oral ingestion in all cases, and especially in those who present an intraoperative AE and longer operation time. [ABSTRACT FROM AUTHOR]

Published
2021
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113. Endoscopic treatment of proton pump inhibitor‐refractory gastroesophageal reflux disease with anti‐reflux mucosectomy: Experience of 109 cases.

Author

Sumi, Kazuya, Inoue, Haruhiro, Kobayashi, Yasutoshi, Iwaya, Yugo, Abad, Mary Raina Angeli, Fujiyoshi, Yusuke, Shimamura, Yuto, Ikeda, Haruo, and Onimaru, Manabu

Subjects
GASTROESOPHAGEAL reflux, PROTON pump inhibitors, MINIMALLY invasive procedures, SCARS, PROTONS, BORTEZOMIB
Abstract

Objectives: Some patients with gastroesophageal reflux disease (GERD) are refractory to proton pump inhibitor (PPI) therapy. Anti‐reflux mucosectomy (ARMS) is a minimally invasive endoscopic procedure for treatment of GERD. In this study, we retrospectively evaluated the outcomes of ARMS performed in patients with PPI‐refractory GERD at our institution. Methods: A total of 109 patients with PPI‐refractory GERD who underwent ARMS were retrospectively reviewed. Pre‐ and post‐ARMS questionnaire scores, acid exposure time (AET), DeMeester score, proximal extent, and PPI discontinuation rate were compared. Results: There was a significant improvement in the symptom score (P < 0.01) and 40–50% of patients were able to discontinue PPI after ARMS. In patients who were followed up for 3 years, sustained improvement in subjective symptoms was observed. AET and DeMeester score significantly improved after ARMS (P < 0.01); however, there was no significant improvement in proximal extent (P = 0.0846). Conclusions: Anti‐reflux mucosectomy is an effective minimally invasive therapy for patients with PPI‐refractory GERD. The therapeutic efficacy is attributable to suppression of acid backflow due to contraction of the scar tissue in cardia. [ABSTRACT FROM AUTHOR]

Published
2021
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114. Peroral endoscopic myotomy and fundoplication: a novel NOTES procedure

Author

Inoue, Haruhiro, additional, Ueno, Akiko, additional, Shimamura, Yuto, additional, Manolakis, Anastassios, additional, Sharma, Ashish, additional, Kono, Shin, additional, Nishimoto, Masayuki, additional, Sumi, Kazuya, additional, Ikeda, Haruo, additional, Goda, Kenichi, additional, Onimaru, Manabu, additional, Yamaguchi, Noriko, additional, and Itoh, Hiroaki, additional

Published
2019
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115. Clinical practice guidelines for peroral endoscopic myotomy

Author

Inoue, Haruhiro, primary, Shiwaku, Hironari, additional, Iwakiri, Katsuhiko, additional, Onimaru, Manabu, additional, Kobayashi, Yasutoshi, additional, Minami, Hitomi, additional, Sato, Hiroki, additional, Kitano, Seigo, additional, Iwakiri, Ryuichi, additional, Omura, Nobuo, additional, Murakami, Kazunari, additional, Fukami, Norio, additional, Fujimoto, Kazuma, additional, and Tajiri, Hisao, additional

Published
2018
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116. Sa1922 ADVANCED ENDOCYTOSCOPY SYSTEM FOR SUPERFICIAL SQUAMOUS NEOPLASMS USING THE NEW SIMPLIFIED CLASSIFICATION

Author

Goda, Kenichi, primary, Shimamura, Yuto, additional, Ikeda, Haruo, additional, Nishikawa, Yohei, additional, Nishimoto, Masayuki, additional, Kono, Shin, additional, Ueno, Akiko, additional, Sumi, Kazuya, additional, Tanabe, Mayo, additional, Ominami, Masaki, additional, Tatsuta, Tetsuya, additional, Ikebuchi, Yuichiro, additional, Onimaru, Manabu, additional, Yamaguchi, Noriko, additional, Ito, Hiroaki, additional, and Inoue, haru, additional

Published
2018
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118. Tu1170 DIAGNOSTIC PERFORMANCE OF AN ENDOSCOPIC PRESSURE INTEGRATED SYSTEM (EPSIS): A NOVEL DIAGNOSTIC TOOL FOR GASTROESOPHAGEAL REFLUX DISEASE

Author

Shimamura, Yuto, primary, Goda, Kenichi, additional, Ominami, Masaki, additional, Nishimoto, Masayuki, additional, Nishikawa, Yohei, additional, Kono, Shin, additional, Ueno, Akiko, additional, Tanabe, Mayo, additional, Sumi, Kazuya, additional, Tatsuta, Tetsuya, additional, Ikebuchi, Yuichiro, additional, Ikeda, Haruo, additional, Onimaru, Manabu, additional, Ito, Hiroaki, additional, and Inoue, Haruhiro, additional

Published
2018
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119. Sa1936 CLINICAL OUTCOME OF PER-ORAL ENDOSCOPIC TUMOR RESECTION FOR SUBMUCOSAL TUMORS OF THE ESOPHAGUS AND GASTRIC CARDIA

Author

Tanabe, Mayo, primary, Kono, Shin, additional, Ominami, Masaki, additional, Nishimoto, Masayuki, additional, Nishikawa, Yohei, additional, Ueno, Akiko, additional, Shimamura, Yuto, additional, Sumi, Kazuya, additional, Ikeda, Haruo, additional, Onimaru, Manabu, additional, Ito, Hiroaki, additional, and Inoue, Haruhiro, additional

Published
2018
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120. Sa1907 CLASSIFICATION AND GRADING OF ADVERSE EVENTS RELATED TO PERORAL ENDOSCOPIC MYOTOMY (POEM): A COMPARISON BETWEEN THE AMERICAN SOCIETY OF GASTROINTESTINAL ENDOSCOPY LEXICON AND THE CLAVIEN-DINDO CLASSIFICATION

Author

Parsa, Nasim, primary, Haito-Chavez, Yamile, additional, Brewer Gutierrez, Olaya I., additional, Paiji, Christopher, additional, Inoue, Hiroyuki, additional, Beard, Kristin W., additional, Draganov, Peter V., additional, Ujiki, Michael, additional, Rahden, Burkhard H.A., additional, Desai, Pankaj N., additional, Pioche, Mathieu, additional, Hayee, Bu, additional, Haji, Amyn, additional, Saxena, Payal, additional, Reavis, Kevin, additional, Onimaru, Manabu, additional, Balassone, Valerio, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Yang, Dennis, additional, Pannu, Davinderbir, additional, Abbas, Ali M., additional, Perbtani, Yaseen B., additional, Patel, Lava, additional, Filser, Jörg, additional, Roman, Sabine, additional, Rivory, Jerome, additional, Mion, Francois, additional, Ponchon, Thierry, additional, Perretta, Silvana, additional, Wong, Vivien W., additional, Maselli, Roberta, additional, Yang, Juliana, additional, Moran, Robert, additional, Sanaei, Omid, additional, Fayad, Lea, additional, Dbouk, Mohamad, additional, Bueno, Renata Pieratti, additional, Kumbhari, Vivek, additional, Repici, Alessandro, additional, and Khashab, Mouen A., additional

Published
2018
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121. Tu1194 CLINICAL OUTCOMES OF ENDOSCOPIC RESECTION FOR ACHALASIA-ASSOCIATED SUPERFICIAL ESOPHAGEAL CANCER

Author

Nishikawa, Yohei, primary, Goda, Kenichi, additional, Ikeda, Haruo, additional, Sharma, Ashish, additional, Nishimoto, Masayuki, additional, Ueno, Akiko, additional, Tanabe, Mayo, additional, Shimamura, Yuto, additional, Kono, Shin, additional, Sumi, Kazuya, additional, Ominami, Masaki, additional, Onimaru, Manabu, additional, Ito, Hiroaki, additional, and Inoue, Haruhiro, additional

Published
2018
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122. Tu1174 A NOVEL FUNCTIONAL ENDOSCOPY FOR GASTROESOPHAGEAL REFLUX DISEASE; ENDOSCOPIC PRESSURE STUDY INTEGRATED SYSTEM

Author

Ominami, Masaki, primary, Shimamura, Yuto, additional, Nishikawa, Yohei, additional, Nishimoto, Masayuki, additional, Ueno, Akiko, additional, Tanabe, Mayo, additional, Kono, Shin, additional, Sumi, Kazuya, additional, Tatsuta, Tetsuya, additional, Ikebuchi, Yuichiro, additional, Ikeda, Haruo, additional, Onimaru, Manabu, additional, Goda, Kenichi, additional, Ito, Hiroaki, additional, and Inoue, Haruhiro, additional

Published
2018
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124. Tu1156 BALLOON DILATION BEFORE PER-ORAL ENDOSCOPIC MYOTOMY IS ASSOCIATED WITH HIGHER RATE OF POSTOPERATIVE GASTROESOPHAGEAL REFLUX: A PROPENSITY SCORE MATCHING ANALYSIS

Author

Kono, Shin, primary, Ikeda, Haruo, additional, Shimamura, Yuto, additional, Sharma, Ashish, additional, Nishimoto, Masayuki, additional, Nishikawa, Yohei, additional, Ueno, Akiko, additional, Tanabe, Mayo, additional, Sumi, Kazuya, additional, Ominami, Masaki, additional, Onimaru, Manabu, additional, Goda, Kenichi, additional, Ito, Hiroaki, additional, and Inoue, Haruhiro, additional

Published
2018
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126. Retraction notice to “Long-term outcomes of per-oral endoscopic myotomy in patients with achalasia with a minimum follow-up of 2 years: an international multicenter study”

Author

Ngamruengphong, Saowanee, primary, Inoue, Haruhiro, additional, Chiu, Philip Wai-Yan, additional, Yip, Hon Chi, additional, Bapaye, Amol, additional, Ujiki, Michael, additional, Patel, Lava, additional, Desai, Pankaj N., additional, Hayee, Bu, additional, Haji, Amyn, additional, Wong, Vivien Wai-yin, additional, Perretta, Silvana, additional, Dorwat, Shivangi, additional, Pioche, Mathieu, additional, Roman, Sabine, additional, Rivory, Jérôme, additional, Mion, François, additional, Ponchon, Thierry, additional, Garros, Aurélien, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Balassone, Valerio, additional, Onimaru, Manabu, additional, Hajiyeva, Gulara, additional, Ismail, Amr, additional, Chen, Yen-I, additional, Bukhari, Majidah, additional, Haito-Chavez, Yamile, additional, Kumbhari, Vivek, additional, Maselli, Roberta, additional, Repici, Alessandro, additional, and Khashab, Mouen A., additional

Published
2018
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127. Comprehensive Analysis of Adverse Events Associated With Per Oral Endoscopic Myotomy in 1826 Patients: An International Multicenter Study

Author

Haito-Chavez, Yamile, primary, Inoue, Haruhiro, additional, Beard, Kristin W, additional, Draganov, Peter V, additional, Ujiki, Michael, additional, Rahden, Burkhard H A, additional, Desai, Pankaj N, additional, Pioche, Mathieu, additional, Hayee, Bu, additional, Haji, Amyn, additional, Saxena, Payal, additional, Reavis, Kevin, additional, Onimaru, Manabu, additional, Balassone, Valerio, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Yang, Dennis, additional, Pannu, Davinderbir, additional, Abbas, Ali, additional, Perbtani, Yaseen B, additional, Patel, Lava Y, additional, Filser, Jorg, additional, Roman, Sabine, additional, Rivory, Jerome, additional, Mion, Francois, additional, Ponchon, Thierry, additional, Perretta, Silvana, additional, Wong, Vivien, additional, Maselli, Roberta, additional, Ngamruengphong, Saowanee, additional, Chen, Yen-I, additional, Bukhari, Majidah, additional, Hajiyeva, Gulara, additional, Ismail, Amr, additional, Pieratti, Renata, additional, Kumbhari, Vivek, additional, Galdos-Cardenas, Gerson, additional, Repici, Alessandro, additional, and Khashab, Mouen A, additional

Published
2017
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132. Is POEM the Answer for Management of Spastic Esophageal Disorders? A Systematic Review and Meta-Analysis

Author

Khan, Muhammad Ali, primary, Kumbhari, Vivek, additional, Ngamruengphong, Saowanee, additional, Ismail, Amr, additional, Chen, Yen-I, additional, Chavez, Yamile Haito, additional, Bukhari, Majidah, additional, Nollan, Richard, additional, Ismail, Mohammad Kashif, additional, Onimaru, Manabu, additional, Balassone, Valerio, additional, Sharata, Ahmed, additional, Swanstrom, Lee, additional, Inoue, Haruhiro, additional, Repici, Alessandro, additional, and Khashab, Mouen A., additional

Published
2016
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134. Response

Author

Bechara, Robert, primary, Onimaru, Manabu, additional, Ikeda, Haruo, additional, and Inoue, Haruhiro, additional

Published
2016
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135. Mo1970 An International Multicenter Study Evaluating the Clinical Efficacy and Safety of PerOral Endoscopic Myotomy (POEM) in Octogenarians

Author

Chen, Yen-I., primary, Inoue, Haruhiro, additional, Ujiki, Michael, additional, Draganov, Peter V., additional, Colavita, Paul D., additional, Mion, Francois, additional, Romanelli, John, additional, Repici, Alessandro, additional, Chiu, Philip W., additional, Balassone, Valerio, additional, Patel, Lava Y., additional, Abbas, Ali, additional, Yang, Dennis, additional, Dunst, Christy M., additional, Pioche, Mathieu, additional, Roman, Sabine, additional, Rivory, Jérôme, additional, Ponchon, Thierry, additional, Desilets, David, additional, Maselli, Roberta, additional, Wong, Vivien, additional, Onimaru, Manabu, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Hajiyeva, Gulara, additional, Ismail, Amr, additional, Ngamruengphong, Saowanee, additional, Bukhari, Majidah, additional, Chavez, Yamile Haito, additional, Kumbhari, Vivek, additional, and Khashab, Mouen A., additional

Published
2016
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136. Tu1245 Is POEM the answer for the management of Spastic Esophageal Disorders? A Systematic Review and Meta-analysis

Author

Khan, Muhammad Ali, primary, Kumbhari, Vivek, additional, Ngamruengphong, Saowanee, additional, Ismail, Amr, additional, Chen, Yen-I., additional, Chavez, Yamile Haito, additional, Bukhari, Majidah, additional, Onimaru, Manabu, additional, Balassone, Valerio, additional, Nollan, Richard, additional, Ismail, Mohammad K., additional, Inoue, Haruhiro, additional, Singh, Vikesh K., additional, and Khashab, Mouen A., additional

Published
2016
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137. 870 Comprehensive Analysis of Adverse Events Associated With PerOral Endoscopic Myotomy (POEM) in 1826 Patients: An International Multicenter Study

Author

Chavez, Yamile Haito, primary, Beard, Kristin W., additional, Inoue, Haruhiro, additional, Draganov, Peter V., additional, Ujiki, Michael, additional, Rahden, Burkhard H.A., additional, Desai, Pankaj N., additional, Repici, Alessandro, additional, Pioche, Mathieu, additional, Hayee, Bu, additional, Saxena, Payal, additional, Reavis, Kevin, additional, Onimaru, Manabu, additional, Balassone, Valerio, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Yang, Dennis, additional, Pannu, Davinderbir, additional, Abbas, Ali, additional, Perbtani, Yaseen B., additional, Patel, Lava Y., additional, Filser, Jorg, additional, Maselli, Roberta, additional, Roman, Sabine, additional, Rivory, Jerome, additional, Mion, Francois, additional, Ponchon, Thierry, additional, Perretta, Silvana, additional, Ngamruengphong, Saowanee, additional, Chen, Yen-I., additional, Bukhari, Majidah, additional, Hajiyeva, Gulara, additional, Ismail, Amr, additional, Kumbhari, Vivek, additional, and Khashab, Mouen A., additional

Published
2016
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138. Tu2049 Long term Outcomes of PerOral Endoscopic Myotomy (POEM) in Achalasia patients With a minimum follow-up of 2 years: A multicenter study

Author

Ngamruengphong, Saowanee, primary, Inoue, Haruhiro, additional, Bapaye, Amol, additional, Ujiki, Michael, additional, Patel, Lava Y., additional, Desai, Pankaj N., additional, Hayee, Bu, additional, Haji, Amyn, additional, Wong, Vivien, additional, Perretta, Silvana, additional, Dorwat, Shivangi, additional, Pioche, Mathieu, additional, Roman, Sabine, additional, Rivory, Jérôme, additional, Mion, Francois, additional, Ponchon, Thierry, additional, Garros, Aurélien, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Balassone, Valerio, additional, Onimaru, Manabu, additional, Hajiyeva, Gulara, additional, Ismail, Amr, additional, Chen, Yen-I., additional, Bukhari, Majidah, additional, Chavez, Yamile Haito, additional, Kumbhari, Vivek, additional, Maselli, Roberta, additional, Repici, Alessandro, additional, and Khashab, Mouen A., additional

Published
2016
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139. 874 Comparative Evaluation of PerOral Endoscopic Myotomy (POEM) for the Treatment of Achalasia in Patients With Failed Heller Myotomy vs Patients Without a History of Surgical Myotomy: A Multicenter Retrospective Cohort Study

Author

Ngamruengphong, Saowanee, primary, Inoue, Haruhiro, additional, Ujiki, Michael, additional, Bapaye, Amol, additional, Desai, Pankaj N., additional, Ponchon, Thierry, additional, Dorwat, Shivangi, additional, Draganov, Peter V., additional, Perbtani, Yaseen B., additional, Abbas, Ali, additional, Pannu, Davinderbir, additional, Yang, Dennis, additional, Perretta, Silvana, additional, Romanelli, John, additional, Desilets, David, additional, Hayee, Bu, additional, Patel, Lava Y., additional, Pioche, Mathieu, additional, Roman, Sabine, additional, Rivory, Jérôme, additional, Mion, Francois, additional, Garros, Aurélien, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Balassone, Valerio, additional, Onimaru, Manabu, additional, Hajiyeva, Gulara, additional, Ismail, Amr, additional, Chen, Yen-I., additional, Bukhari, Majidah, additional, Chavez, Yamile Haito, additional, Kumbhari, Vivek, additional, Maselli, Roberta, additional, Repici, Alessandro, additional, and Khashab, Mouen A., additional

Published
2016
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140. New endoscopic classification of the cardiac orifice in esophageal achalasia: Champagne glass sign

Author

Gomi, Kuniyo, primary, Inoue, Haruhiro, additional, Ikeda, Haruo, additional, Bechara, Robert, additional, Sato, Chiaki, additional, Ito, Hiroaki, additional, Onimaru, Manabu, additional, Kitamura, Yohei, additional, Suzuki, Michitaka, additional, Nakamura, Jun, additional, Hata, Yoshitaka, additional, Maruyama, Shota, additional, Sumi, Kazuya, additional, and Takahashi, Hiroshi, additional

Published
2016
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142. Training in peroral endoscopic myotomy (POEM) for esophageal achalasia

Author

Eleftheriadis , Nicholas, Inoue,Haruhiro, Ikeda,Haruo, Onimaru,Manabu, Yoshida,Akira, Hosoya,Toshihisa, Maselli,Roberta, and Kudo,Shin-ei

Subjects
Therapeutics and Clinical Risk Management
Abstract

Nicholas Eleftheriadis, Haruhiro Inoue, Haruo Ikeda, Manabu Onimaru, Akira Yoshida, Toshihisa Hosoya, Roberta Maselli, Shin-ei KudoDigestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, JapanAbstract: Peroral endoscopic myotomy (POEM) has been developed in the context of natural orifice transluminal endoscopic surgery (NOTES) as a minimally invasive endoscopic treatment for symptomatic esophageal achalasia, which is a chronic progressive benign disease with severe morbidity and difficult management. Since September 2008, POEM has been successfully performed in more than 200 consecutive patients with symptomatic achalasia at the Digestive Disease Center of Showa University, Northern Yokohama Hospital, Yokohama, Japan, with excellent short- and long-term results and absence of serious complications. International experience of POEM within clinical studies is also promising. According to these results, POEM is considered as a safe procedure that can be applied to all achalasia patients. However, the low incidence of achalasia (0.3%–1% per 100,000 population), in combination with the potential serious complications related to the technically demanding POEM procedure, has made training difficult. There is therefore an urgent need for an animal model for training to decrease the learning curve. Further, there are other ethical and training issues to address. The pig is the most appropriate animal model for training in POEM due to its anatomy being similar to that of humans. The porcine esophagus has the advantage of easy mobilization due to absence of tight junctions to surrounding organs. A non-survival porcine model would be a simple, inexpensive, and reproducible animal model for training in POEM, without the need for concern about complications. A possible training process might first involve observation of POEM performed by specialists, then training on non-survival and survival porcine models, followed by training in humans under specialist guidance and finally, performance of POEM in humans.Keywords: porcine organ model, non-survival, porcine esophagus, Heller myotomy

Published
2012

147. Peroral endoscopic myotomy (POEM) vs laparoscopic Heller myotomy (LHM) for the treatment of Type III achalasia in 75 patients: a multicenter comparative study

Author

Kumbhari, Vivek, additional, Tieu, Alan, additional, Onimaru, Manabu, additional, El Zein, Mohammad, additional, Teitelbaum, Ezra, additional, Ujiki, Michael, additional, Gitelis, Matthew, additional, Modayil, Rani, additional, Hungness, Eric, additional, Stavropoulos, Stavros, additional, Shiwaku, Hiro, additional, Kunda, Rastislav, additional, Chiu, Philip, additional, Saxena, Payal, additional, Messallam, Ahmed, additional, Inoue, Haruhiro, additional, and Khashab, Mouen, additional

Published
2015
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148. Simple blood test for diagnosis of gastrointestinal and pancreas cancer using surface-enhanced Raman scattering.

Author

Ito, Hiroaki, primary, Hasegawa, Katsuyuki, additional, Hasegawa, Yuuki, additional, Kimura, Satoshi, additional, Onimaru, Manabu, additional, Ohmori, Tohru, additional, Ikeda, Haruo, additional, Saito, Mitsuo, additional, Kitamura, Yohei, additional, Sato, Chiaki, additional, Gomi, Kuniyo, additional, Sakaue, Satoshi, additional, Isozaki, Masayuki, additional, Matsukawa, Masaaki, additional, and Inoue, Haruhiro, additional

Published
2015
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