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101. A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis

Author

Carolien M. Woolthuis, André B. Mulder, Rikst Nynke Verkaik-Schakel, Stefano Rosati, Arjan Diepstra, Eva van den Berg, Jan Jacob Schuringa, Edo Vellenga, Philip M. Kluin, and Gerwin Huls

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Abstract

Mutations of nucleophosmin 1 are frequently found in acute myeloid leukemia and lead to aberrant cytoplasmic accumulation of nucleophosmin protein. Immunohistochemical staining is therefore recommended as the technique of choice in front-line screening. In this study, we assessed the sensitivity and specificity of immunohistochemistry on formalin-fixed bone marrow biopsies compared with gold standard molecular analysis to predict nucleophosmin 1 mutation status in 119 patients with acute myeloid leukemia. Discrepant cases were further characterized by gene expression analyses and fluorescence in situ hybridization. A large overlap between both methods was observed. Nevertheless, nine patients demonstrated discordant results at initial screening. Five cases demonstrated nuclear staining of nucleophosmin 1 by immunohistochemistry, but a nucleophosmin 1 mutation by molecular analysis. In two cases this could be attributed to technical issues and in three cases minor subpopulations of myeloblasts had not been discovered initially. All tested cases exhibited the characteristic nucleophosmin-mutated gene expression pattern. Four cases had cytoplasmic nucleophosmin 1 staining and a nucleophosmin-mutated gene expression pattern without a detectable nucleophosmin 1 mutation. In two of these cases we found the chromosomal translocation t(3;5)(q25;q35) encoding the NPM-MLF1 fusion protein. In the other discrepant cases the aberrant cytoplasmic nucleophosmin staining and gene expression could not be explained. In total six patients (5%) had true discordant results between immunohistochemistry and mutation analysis. We conclude that cytoplasmic nucleophosmin localization is not always caused by a conventional nucleophosmin 1 mutation and that in the screening for nucleophosmin 1 abnormalities, most information will be obtained by combining immunohistochemistry with molecular analysis.

Published
2013
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102. Technology review of the Northern Bowen and Galilee basins

Author

Scott, Michael P., Johnson Jr, Raymond, Spilsbury-Schakel, Janny, and Garnett, Andrew

Abstract

This paper reviews and summarises the work that has been conducted and the technology used in exploring and developing the Northern Bowen and Galilee basins in Queensland. It examines the methods operators have used in drilling, completing and testing wells through the varying stages of exploration, appraisal and development in the different parts of the basins. It examines all the work conducted in the Betts Creek Beds and Aramac Coal Measures throughout the Galilee Basin; the Moranbah Coal Measures, Rangal Coal Measures and Fort Cooper Coal Measures in the Moranbah area of the Bowen Basin; the Rangal Coal Measures, Burngrove Formation and Fairhill Formation in the Blackwater area; the conventional and coal seam gas developments in the Rolleston area, including the Bandanna Formation plays near Injune; and the Baralaba Coal Measures in the Moura area. Wells have been completed both open and cased hole with techniques including vertical wells, both with and without hydraulic fracturing and cavitation, as well as a variety of horizontal well designs including surface to inseam wells with vertical intercept wells and multiple lateral sections, chevron wells and both heel and toe intercepts. Operators have also implemented multiple wells on one pad. Throughout the Northern Bowen Basin, horizontal well drilling has been a key technology in commercial development. Generally, activities within the Galilee Basin have not progressed as far as the Bowen Basin, but nevertheless, horizontal wells are also emerging as a key technology.

Published
2023
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104. Proton-and Neutron-Induced Single-Event Upsets in FPGAs for the PANDA Experiment

Author

M. Preston, P.-E. Tegnér, P. Schakel, Pawel Marciniewski, Hans Calén, M. Kavatsyuk, K. Makonyi, Tord Johansson, and Research unit Nuclear & Hadron Physics

Subjects
Physics, Nuclear and High Energy Physics, Luminosity (scattering theory), Annihilation, Proton, 010308 nuclear & particles physics, PANDA, Monte Carlo method, 7. Clean energy, 01 natural sciences, Field-programmable gate array (FPGA) configuration memory, Monte Carlo simulations, single-event upsets (SEUs), Momentum, Nuclear physics, Computer Science::Hardware Architecture, Nuclear Energy and Engineering, Antiproton, 0103 physical sciences, Neutron, Electrical and Electronic Engineering, Nuclear Experiment, Energy (signal processing)
Abstract

Single-event upsets (SEUs) affecting the configuration memory of a 28-nm field-programmable gate array (FPGA) have been studied through experiments and Monte Carlo modeling. This FPGA will be used in the front-end electronics of the electromagnetic calorimeter in PANDA (Antiproton Annihilation at Darmstadt), an upcoming hadron-physics experiment. Results from proton and neutron irradiations of the FPGA are presented and shown to be in agreement with previous experimental results. To estimate the mean time between SEUs during operation of PANDA, a Geant4-based Monte Carlo model of the phenomenon has been used. This model describes the energy deposition by particles in a silicon volume, the subsequent drift and diffusion of charges in the FPGA memory cell, and the eventual collection of charges in the sensitive regions of the cell. The values of the two free parameters of the model, the sensitive volume side $d = 87$ nm and the critical charge $Q_{\text {crit}} = 0.23$ fC, were determined by fitting the model to the experimental data. The results of the model agree well with both the proton and neutron data and are also shown to correctly predict the cross sections for upsets induced by other particles. The model-predicted energy dependence of the cross section for neutron-induced upsets has been used to estimate the rate of SEUs during initial operation of PANDA. At a luminosity of $1\cdot 10^{31}$ cm $^{-2}\,\,\text{s}^{-1}$ , the predicted mean time between upsets (MTBU) is between 120 and 170 h per FPGA, depending on the beam momentum.

Published
2020

105. Experimental Validation of the Electrokinetic Theory and Development of Seismoelectric Interferometry by Cross-Correlation

Author

F. C. Schoemaker, N. Grobbe, M. D. Schakel, S. A. L. de Ridder, E. C. Slob, and D. M. J. Smeulders

Subjects
Geophysics. Cosmic physics, QC801-809
Abstract

We experimentally validate a relatively recent electrokinetic formulation of the streaming potential (SP) coefficient as developed by Pride (1994). The start of our investigation focuses on the streaming potential coefficient, which gives rise to the coupling of mechanical and electromagnetic fields. It is found that the theoretical amplitude values of this dynamic SP coefficient are in good agreement with the normalized experimental results over a wide frequency range, assuming no frequency dependence of the bulk conductivity. By adopting the full set of electrokinetic equations, a full-waveform wave propagation model is formulated. We compare the model predictions, neglecting the interface response and modeling only the coseismic fields, with laboratory measurements of a seismic wave of frequency 500 kHz that generates electromagnetic signals. Agreement is observed between measurement and electrokinetic theory regarding the coseismic electric field. The governing equations are subsequently adopted to study the applicability of seismoelectric interferometry. It is shown that seismic sources at a single boundary location are sufficient to retrieve the 1D seismoelectric responses, both for the coseismic and interface components, in a layered model.

Published
2012
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109. Car-Following Properties of a Commercial Adaptive Cruise Control System: A Pilot Field Test

Author

Raju, Narayana, Schakel, Wouter, Reddy, Nagarjun, Dong, Yongqi, and Farah, Haneen

Abstract

Automated driving systems, which can take over certain dynamic driving tasks from the driver, are becoming increasingly available in commercial vehicles. One of these automated driving systems widely introduced in commercial vehicles is adaptive cruise control (ACC). This system is designed to maintain certain desired driving speeds and time headways as chosen by drivers and based on the settings available within the system. The properties and actual performance of these systems will affect the traffic flow and its stability. However, the specific properties and their workings are rarely publicly available. Therefore, the main aim of this paper is to test the actual performance of a commercial ACC system under different desired speed and distance gap settings, as well as driving modes in a car-following situation. For this purpose, a pilot field test was conducted in the Netherlands in which two identical commercial vehicles equipped with ACC systems were driven simultaneously. The first vehicle was used to create a pre-specified speed profile by adapting the ACC system settings manually, whereas the second vehicle followed the lead vehicle when the ACC system was engaged to test its actual performance. The main findings indicate that the different system settings affect the car-following indicators, and system response times were found to be comparable to human response times. The eco mode was found to affect some of the car-following indicators, and it does not deteriorate safety below the safety level of driving with short headway setting in drive mode.

Published
2022
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110. Technical design report for the $\overline{{\rm{P}}}\mathrm{ANDA}$ Barrel DIRC detector

Author

B Singh, W Erni, B Krusche, M Steinacher, N Walford, B Liu, H Liu, Z Liu, X Shen, C Wang, J Zhao, M Albrecht, T Erlen, F Feldbauer, M Fink, M Fritsch, J Haase, F H Heinsius, T Held, T Holtmann, I Keshk, H Koch, B Kopf, M Kuhlmann, M Kümmel, S Leiber, M Mikirtychyants, P Musiol, A Mustafa, M Pelizäus, A Pitka, J Pychy, M Richter, C Schnier, T Schröder, C Sowa, M Steinke, T Triffterer, U Wiedner, M Ball, R Beck, C Hammann, B Ketzer, M Kube, P Mahlberg, M Rossbach, C Schmidt, R Schmitz, U Thoma, M Urban, D Walther, C Wendel, A Wilson, A Bianconi, M Bragadireanu, D Pantea, B Patel, W Czyzycki, M Domagala, G Filo, J Jaworowski, M Krawczyk, E Lisowski, F Lisowski, M Michałek, P Poznański, J Płażek, K Korcyl, A Kozela, P Kulessa, P Lebiedowicz, K Pysz, W Schäfer, A Szczurek, T Fiutowski, M Idzik, B Mindur, K Swientek, J Biernat, B Kamys, S Kistryn, G Korcyl, W Krzemien, A Magiera, P Moskal, A Pyszniak, Z Rudy, P Salabura, J Smyrski, P Strzempek, A Wronska, I Augustin, R Böhm, I Lehmann, D Nicmorus Marinescu, L Schmitt, V Varentsov, A Ali, M Al-Turany, A Belias, H Deppe, N Divani Veis, R Dzhygadlo, H Flemming, A Gerhardt, K Götzen, A Gromliuk, L Gruber, R Hohler, G Kalicy, R Karabowicz, R Kliemt, M Krebs, U Kurilla, D Lehmann, S Löchner, J Lühning, U Lynen, F Nerling, H Orth, M Patsyuk, K Peters, T Saito, G Schepers, C J Schmidt, C Schwarz, J Schwiening, A Täschner, M Traxler, C Ugur, B Voss, P Wieczorek, A Wilms, M Zühlsdorf, V Abazov, G Alexeev, V A Arefiev, V Astakhov, M Yu Barabanov, B V Batyunya, Y Davydov, V Kh Dodokhov, A Efremov, A Fechtchenko, A G Fedunov, A Galoyan, S Grigoryan, E K Koshurnikov, Y Yu Lobanov, V I Lobanov, A F Makarov, L V Malinina, V Malyshev, A G Olshevskiy, E Perevalova, A A Piskun, T Pocheptsov, G Pontecorvo, V Rodionov, Y Rogov, R Salmin, A Samartsev, M G Sapozhnikov, G Shabratova, N B Skachkov, A N Skachkova, E A Strokovsky, M Suleimanov, R Teshev, V Tokmenin, V Uzhinsky, A Vodopianov, S A Zaporozhets, N I Zhuravlev, A Zinchenko, D Branford, D Glazier, D Watts, M Böhm, A Britting, W Eyrich, A Lehmann, M Pfaffinger, F Uhlig, S Dobbs, K Seth, A Tomaradze, T Xiao, D Bettoni, V Carassiti, A Cotta Ramusino, P Dalpiaz, A Drago, E Fioravanti, I Garzia, M Savrie, V Akishina, S Gorbunov, I Kisel, G Kozlov, M Pugach, M Zyzak, P Gianotti, C Guaraldo, V Lucherini, A Bersani, G Bracco, M Macri, R F Parodi, K Biguenko, K T Brinkmann, V Di Pietro, S Diehl, V Dormenev, M Düren, E Etzelmüller, K Föhl, M Galuska, E Gutz, C Hahn, A Hayrapetyan, M Kesselkaul, K Kreutzfeldt, W Kühn, T Kuske, J S Lange, Y Liang, V Metag, M Moritz, M Nanova, R Novotny, T Quagli, S Reiter, A Riccardi, J Rieke, C Rosenbaum, M Schmidt, R Schnell, H Stenzel, U Thöring, M N Wagner, T Wasem, B Wohlfahrt, H G Zaunick, E Tomasi-Gustafsson, D Ireland, G Rosner, B Seitz, P N Deepak, A Kulkarni, A Apostolou, M Babai, M Kavatsyuk, P J Lemmens, M Lindemulder, H Loehner, J Messchendorp, P Schakel, H Smit, M Tiemens, J C van der Weele, R Veenstra, S Vejdani, K Dutta, K Kalita, A Kumar, A Roy, H Sohlbach, M Bai, L Bianchi, M Büscher, L Cao, A Cebulla, R Dosdall, A Erven, V Fracassi, A Gillitzer, F Goldenbaum, D Grunwald, A Herten, Q Hu, L Jokhovets, G Kemmerling, H Kleines, A Lai, A Lehrach, R Nellen, H Ohm, S Orfanitski, D Prasuhn, E Prencipe, J Pütz, J Ritman, E Rosenthal, S Schadmand, T Sefzick, V Serdyuk, G Sterzenbach, T Stockmanns, P Wintz, P Wüstner, H Xu, S Li, Z Li, Z Sun, V Rigato, L Isaksson, P Achenbach, A Aycock, O Corell, A Denig, M Distler, M Hoek, A Karavdina, W Lauth, H Merkel, U Müller, J Pochodzalla, S Sanchez, S Schlimme, C Sfienti, M Thiel, H Ahmadi, null S Ahmed, S Bleser, L Capozza, M Cardinali, A Dbeyssi, M Deiseroth, A Ehret, B Fröhlich, D Kang, D Khaneft, R Klasen, H H Leithoff, D Lin, F Maas, S Maldaner, M Martínez, M Michel, M C Mora Espí, C Morales Morales, C Motzko, O Noll, S Pflüger, D Rodríguez Piñeiro, A Sanchez-Lorente, M Steinen, R Valente, M Zambrana, I Zimmermann, A Fedorov, M Korjik, O Missevitch, A Balashoff, A Boukharov, O Malyshev, I Marishev, P Balanutsa, V Balanutsa, V Chernetsky, A Demekhin, A Dolgolenko, P Fedorets, A Gerasimov, V Goryachev, V Chandratre, V Datar, D Dutta, V Jha, H Kumawat, A K Mohanty, A Parmar, A K Rai, B Roy, G Sonika, C Fritzsch, S Grieser, A K Hergemöller, B Hetz, N Hüsken, A Khoukaz, J P Wessels, K Khosonthongkee, C Kobdaj, A Limphirat, P Srisawad, Y Yan, E Antokhin, A Yu Barnyakov, M Barnyakov, K Beloborodov, V E Blinov, V S Bobrovnikov, I A Kuyanov, K Martin, A P Onuchin, S Pivovarov, E Pyata, S Serednyakov, A Sokolov, Y Tikhonov, A E Blinov, S Kononov, E A Kravchenko, E Atomssa, R Kunne, D Marchand, B Ramstein, J van de Wiele, Y Wang, G Boca, S Costanza, P Genova, P Montagna, A Rotondi, M Bodlak, M Finger, A Nikolovova, M Pesek, M Peskova, M Pfeffer, I Prochazka, M Slunecka, P Gallus, V Jary, J Novy, M Tomasek, M Virius, V Vrba, V Abramov, N Belikov, S Bukreeva, A Davidenko, A Derevschikov, Y Goncharenko, V Grishin, V Kachanov, V Kormilitsin, A Levin, Y Melnik, N Minaev, V Mochalov, D Morozov, L Nogach, S Poslavskiy, A Ryazantsev, S Ryzhikov, P Semenov, I Shein, A Uzunian, A Vasiliev, A Yakutin, U Roy, B Yabsley, S Belostotski, G Gavrilov, A Izotov, S Manaenkov, O Miklukho, D Veretennikov, A Zhdanov, K Makonyi, M Preston, P E Tegner, D Wölbing, T Bäck, B Cederwall, S Godre, F Balestra, F Iazzi, R Introzzi, A Lavagno, J Olave, A Amoroso, M P Bussa, L Busso, M Destefanis, L Fava, L Ferrero, M Greco, J Hu, L Lavezzi, M Maggiora, G Maniscalco, S Marcello, S Sosio, S Spataro, D Calvo, S Coli, P De Remigis, A Filippi, G Giraudo, S Lusso, G Mazza, M Mignone, A Rivetti, R Wheadon, R Birsa, F Bradamante, A Bressan, A Martin, H Calen, W Ikegami Andersson, T Johansson, A Kupsc, P Marciniewski, M Papenbrock, J Pettersson, K Schönning, M Wolke, B Galnander, J Diaz, V Pothodi Chackara, A Chlopik, G Kesik, D Melnychuk, B Slowinski, A Trzcinski, M Wojciechowski, S Wronka, B Zwieglinski, P Bühler, J Marton, D Steinschaden, K Suzuki, E Widmann, S Zimmermann, and J Zmeskal

Subjects
Physics, Nuclear and High Energy Physics, Range (particle radiation), Large Hadron Collider, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Hadron, Detector, Barrel (horology), 7. Clean energy, 01 natural sciences, Ring-imaging Cherenkov detector, Particle identification, Charged particle, Nuclear physics, 0103 physical sciences, High Energy Physics::Experiment, ddc:530, 010306 general physics, Nuclear Experiment
Abstract

The $\overline{{\rm{P}}}\mathrm{ANDA}$ (anti-Proton ANnihiliation at DArmstadt) experiment will be one of the four flagship experiments at the new international accelerator complex FAIR (Facility for Antiproton and Ion Research) in Darmstadt, Germany. $\overline{{\rm{P}}}\mathrm{ANDA}$ will address fundamental questions of hadron physics and quantum chromodynamics using high-intensity cooled antiproton beams with momenta between 1.5 and 15 GeV/c and a design luminosity of up to 2 × 1032 cm−2 s−1. Excellent particle identification (PID) is crucial to the success of the $\overline{{\rm{P}}}\mathrm{ANDA}$ physics program. Hadronic PID in the barrel region of the target spectrometer will be performed by a fast and compact Cherenkov counter using the detection of internally reflected Cherenkov light (DIRC) technology. It is designed to cover the polar angle range from 22° to 140° and will provide at least 3 standard deviations (s.d.) π/K separation up to 3.5 GeV/c, matching the expected upper limit of the final state kaon momentum distribution from simulation. This documents describes the technical design and the expected performance of the $\overline{{\rm{P}}}\mathrm{ANDA}$ Barrel DIRC detector. The design is based on the successful BaBar DIRC with several key improvements. The performance and system cost were optimized in detailed detector simulations and validated with full system prototypes using particle beams at GSI and CERN. The final design meets or exceeds the PID goal of clean π/K separation with at least 3 s.d. over the entire phase space of charged kaons in the Barrel DIRC.

Published
2019
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112. Altered neurodevelopmental DNA methylation status after fetal growth restriction with brain-sparing

Author

Richter, Anne E., Bekkering-Bauer, Iris, Verkaik-Schakel, Rikst Nynke, Leeuwerke, Mariëtte, Tanis, Jozien C., Bilardo, Caterina M., Kooi, Elisabeth M. W., Scherjon, Sicco A., Bos, Arend F., and Plösch, Torsten

Abstract

AbstractIt is under debate how preferential perfusion of the brain (brain-sparing) in fetal growth restriction (FGR) relates to long-term neurodevelopmental outcome. Epigenetic modification of neurotrophic genes by altered fetal oxygenation may be involved. To explore this theory, we performed a follow-up study of 21 FGR children, in whom we prospectively measured the prenatal cerebroplacental ratio (CPR) with Doppler sonography. At 4 years of age, we tested their neurodevelopmental outcome using the Wechsler Preschool and Primary Scale of Intelligence, the Child Behavior Checklist, and the Behavior Rating Inventory of Executive Function. In addition, we collected their buccal DNA to determine the methylation status at predefined genetic regions within the genes hypoxia-inducible factor-1 alpha (HIF1A), vascular endothelial growth factor A (VEGFA), erythropoietin (EPO), EPO-receptor (EPOR), brain-derived neurotrophic factor (BDNF), and neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) by pyrosequencing. We found that FGR children with fetal brain-sparing (CPR <1, n= 8) demonstrated a trend (0.05 < p< 0.1) toward hypermethylation of HIF1Aand VEGFAat their hypoxia-response element (HRE) compared with FGR children without fetal brain-sparing. Moreover, in cases with fetal brain-sparing, we observed statistically significant hypermethylation at a binding site for cyclic adenosine monophophate response element binding protein (CREB) of BDNFpromoter exon 4 and hypomethylation at an HRE located within the NTRK2promoter (both p<0.05). Hypermethylation of VEGFAwas associated with a poorer Performance Intelligence Quotient, while hypermethylation of BDNFwas associated with better inhibitory self-control (both p<0.05). These results led us to formulate the hypothesis that early oxygen-dependent epigenetic alterations due to hemodynamic alterations in FGR may be associated with altered neurodevelopmental outcome in later life. We recommend further studies to test this hypothesis.

Published
2022
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113. Study of doubly strange systems using stored antiprotons

Author

B. Singh, W. Erni, B. Krusche, M. Steinacher, N. Walford, B. Liu, H. Liu, Z. Liu, X. Shen, C. Wang, J. Zhao, M. Albrecht, T. Erlen, M. Fink, F. Heinsius, T. Held, T. Holtmann, S. Jasper, I. Keshk, H. Koch, B. Kopf, M. Kuhlmann, M. Kümmel, S. Leiber, M. Mikirtychyants, P. Musiol, A. Mustafa, M. Pelizäus, J. Pychy, M. Richter, C. Schnier, T. Schröder, C. Sowa, M. Steinke, T. Triffterer, U. Wiedner, M. Ball, R. Beck, C. Hammann, B. Ketzer, M. Kube, P. Mahlberg, M. Rossbach, C. Schmidt, R. Schmitz, U. Thoma, M. Urban, D. Walther, C. Wendel, A. Wilson, A. Bianconi, M. Bragadireanu, M. Caprini, D. Pantea, B. Patel, W. Czyzycki, M. Domagala, G. Filo, J. Jaworowski, M. Krawczyk, E. Lisowski, F. Lisowski, M. Michałek, P. Poznański, J. Płażek, K. Korcyl, A. Kozela, P. Kulessa, P. Lebiedowicz, K. Pysz, W. Schäfer, A. Szczurek, T. Fiutowski, M. Idzik, B. Mindur, D. Przyborowski, K. Swientek, J. Biernat, B. Kamys, S. Kistryn, G. Korcyl, W. Krzemien, A. Magiera, P. Moskal, A. Psyzniak, Z. Rudy, P. Salabura, J. Smyrski, P. Strzempek, A. Wronska, I. Augustin, R. Böhm, I. Lehmann, D. Nicmorus Marinescu, L. Schmitt, V. Varentsov, M. Al-Turany, A. Belias, H. Deppe, R. Dzhygadlo, A. Ehret, H. Flemming, A. Gerhardt, K. Götzen, A. Gromliuk, L. Gruber, R. Karabowicz, R. Kliemt, M. Krebs, U. Kurilla, D. Lehmann, S. Löchner, J. Lühning, U. Lynen, H. Orth, M. Patsyuk, K. Peters, T. Saito, G. Schepers, C.J. Schmidt, C. Schwarz, J. Schwiening, A. Täschner, M. Traxler, C. Ugur, B. Voss, P. Wieczorek, A. Wilms, M. Zühlsdorf, V.M. Abazov, G. Alexeev, A. Arefiev, V.I. Astakhov, M.Yu. Barabanov, B.V. Batyunya, Yu.I. Davydov, V.Kh. Dodokhov, A.A. Efremov, A. Fechtchenko, A.G. Fedunov, A. Galoyan, S. Grigoryan, E.K. Koshurnikov, V.I. Lobanov, Y.Yu. Lobanov, A.F. Makarov, L.V. Malinina, V.L. Malyshev, A. Olshevskiy, E. Perevalova, A.A. Piskun, T. Pocheptsov, G. Pontecorvo, V. Rodionov, Y. Rogov, R. Salmin, A. Samartsev, M.G. Sapozhnikov, G. Shabratova, N.B. Skachkov, A.N. Skachkova, E.A. Strokovsky, M. Suleimanov, R. Teshev, V. Tokmenin, V. Uzhinsky, A. Vodopyanov, S.A. Zaporozhets, N.I. Zhuravlev, A.G. Zorin, D. Branford, D. Glazier, D. Watts, M. Böhm, A. Britting, W. Eyrich, A. Lehmann, M. Pfaffinger, F. Uhlig, S. Dobbs, K. Seth, A. Tomaradze, T. Xiao, D. Bettoni, V. Carassiti, A. Cotta Ramusino, P. Dalpiaz, A. Drago, E. Fioravanti, I. Garzia, M. Savriè, V. Akishina, I. Kisel, G. Kozlov, M. Pugach, M. Zyzak, P. Gianotti, C. Guaraldo, V. Lucherini, A. Bersani, G. Bracco, M. Macri, R.F. Parodi, K. Biguenko, K. Brinkmann, V. Di Pietro, S. Diehl, V. Dormenev, P. Drexler, M. Düren, E. Etzelmüller, M. Galuska, E. Gutz, C. Hahn, A. Hayrapetyan, M. Kesselkaul, W. Kühn, T. Kuske, J.S. Lange, Y. Liang, V. Metag, M. Nanova, S. Nazarenko, R. Novotny, T. Quagli, S. Reiter, J. Rieke, C. Rosenbaum, M. Schmidt, R. Schnell, H. Stenzel, U. Thöring, M. Ullrich, M.N. Wagner, T. Wasem, B. Wohlfarth, H. Zaunick, D. Ireland, G. Rosner, B. Seitz, P.N. Deepak, A. Kulkarni, A. Apostolou, M. Babai, M. Kavatsyuk, P. Lemmens, M. Lindemulder, H. Loehner, J. Messchendorp, P. Schakel, H. Smit, M. Tiemens, J.C. van der Weele, R. Veenstra, S. Vejdani, K. Dutta, K. Kalita, A. Kumar, A. Roy, H. Sohlbach, M. Bai, L. Bianchi, M. Büscher, L. Cao, A. Cebulla, R. Dosdall, A. Gillitzer, F. Goldenbaum, D. Grunwald, A. Herten, Q. Hu, G. Kemmerling, H. Kleines, A. Lehrach, R. Nellen, H. Ohm, S. Orfanitski, D. Prasuhn, E. Prencipe, J. Pütz, J. Ritman, S. Schadmand, T. Sefzick, V. Serdyuk, G. Sterzenbach, T. Stockmanns, P. Wintz, P. Wüstner, H. Xu, A. Zambanini, S. Li, Z. Li, Z. Sun, V. Rigato, L. Isaksson, P. Achenbach, O. Corell, A. Denig, M. Distler, M. Hoek, A. Karavdina, W. Lauth, H. Merkel, U. Müller, J. Pochodzalla, S. Schlimme, C. Sfienti, M. Thiel, H. Ahmadi, S. Ahmed, S. Bleser, L. Capozza, M. Cardinali, A. Dbeyssi, M. Deiseroth, F. Feldbauer, M. Fritsch, B. Fröhlich, P. Jasinski, D. Kang, D. Khaneft, R. Klasen, H.H. Leithoff, D. Lin, F. Maas, S. Maldaner, M. Martìnez Rojo, M. Marta, M. Michel, M.C. Mora Espì, C. Morales Morales, C. Motzko, F. Nerling, O. Noll, S. Pflüger, A. Pitka, D. Rodríguez Piñeiro, A. Sanchez Lorente, M. Steinen, R. Valente, T. Weber, M. Zambrana, I. Zimmermann, A. Fedorov, M. Korjik, O. Missevitch, A. Boukharov, O. Malyshev, I. Marishev, P. Balanutsa, V. Balanutsa, V. Chernetsky, A. Demekhin, A. Dolgolenko, P. Fedorets, A. Gerasimov, V. Goryachev, V. Chandratre, V. Datar, D. Dutta, V. Jha, H. Kumawat, A.K. Mohanty, A. Parmar, B. Roy, G. Sonika, C. Fritzsch, S. Grieser, A.K. Hergemöller, B. Hetz, N. Hüsken, A. Khoukaz, J.P. Wessels, K. Khosonthongkee, C. Kobdaj, A. Limphirat, P. Srisawad, Y. Yan, M. Barnyakov, A.Yu. Barnyakov, K. Beloborodov, A.E. Blinov, V.E. Blinov, V.S. Bobrovnikov, S. Kononov, E.A. Kravchenko, I.A. Kuyanov, K. Martin, A.P. Onuchin, S. Serednyakov, A. Sokolov, Y. Tikhonov, E. Atomssa, R. Kunne, D. Marchand, B. Ramstein, J. Van de Wiele, Y. Wang, G. Boca, S. Costanza, P. Genova, P. Montagna, A. Rotondi, V. Abramov, N. Belikov, S. Bukreeva, A. Davidenko, A. Derevschikov, Y. Goncharenko, V. Grishin, V. Kachanov, V. Kormilitsin, A. Levin, Y. Melnik, N. Minaev, V. Mochalov, D. Morozov, L. Nogach, S. Poslavskiy, A. Ryazantsev, S. Ryzhikov, P. Semenov, I. Shein, A. Uzunian, A. Vasiliev, A. Yakutin, E. Tomasi-Gustafsson, U. Roy, B. Yabsley, S. Belostotski, G. Gavrilov, A. Izotov, S. Manaenkov, O. Miklukho, D. Veretennikov, A. Zhdanov, K. Makonyi, M. Preston, P. Tegner, D. Wölbing, T. Bäck, B. Cederwall, A.K. Rai, S. Godre, D. Calvo, S. Coli, P. De Remigis, A. Filippi, G. Giraudo, S. Lusso, G. Mazza, M. Mignone, A. Rivetti, R. Wheadon, F. Balestra, F. Iazzi, R. Introzzi, A. Lavagno, J. Olave, A. Amoroso, M.P. Bussa, L. Busso, F. De Mori, M. Destefanis, L. Fava, L. Ferrero, M. Greco, J. Hu, L. Lavezzi, M. Maggiora, G. Maniscalco, S. Marcello, S. Sosio, S. Spataro, R. Birsa, F. Bradamante, A. Bressan, A. Martin, H. Calen, W. Ikegami Andersson, T. Johansson, A. Kupsc, P. Marciniewski, M. Papenbrock, J. Pettersson, K. Schönning, M. Wolke, B. Galnander, J. Diaz, V. Pothodi Chackara, A. Chlopik, G. Kesik, D. Melnychuk, B. Slowinski, A. Trzcinski, M. Wojciechowski, S. Wronka, B. Zwieglinski, P. Bühler, J. Marton, D. Steinschaden, K. Suzuki, E. Widmann, J. Zmeskal, Jürgen Gerl, Ivan Kojouharov, Jasmina Kojouharova, and Research unit Nuclear & Hadron Physics

Subjects
Particle physics, Nuclear and High Energy Physics, COLLISIONS, Strong interaction, Nuclear Theory, hyperatoms, Antiprotons, Hyperatoms, Hypernuclei, Strangeness, EXCHANGE CURRENTS, 01 natural sciences, Partícules (Física nuclear), NO, Nuclear physics, Subatomär fysik, Hypemuclei, strangeness, DECUPLET BARYONS, ELECTRIC QUADRUPOLE-MOMENTS, 0103 physical sciences, Subatomic Physics, 010306 general physics, Nuclear Experiment, Physics, hypernuclei, NUCLEI, 010308 nuclear & particles physics, Hyperon, Transport theory, DOUBLE-LAMBDA-HYPERNUCLEI, MODEL, OMEGA, Antiproton, Physics::Accelerator Physics, Heavy ion, High Energy Physics::Experiment, antiprotons, INTERMEDIATE ENERGIES, EMULSION
Abstract

Bound nuclear systems with two units of strangeness are still poorly known despite their importance for many strong interaction phenomena. Stored antiprotons beams in the GeV range represent an unparalleled factory for various hyperon-antihyperon pairs. Their outstanding large production probability in antiproton collisions will open the floodgates for a series of new studies of systems which contain two or even more units of strangeness at the PANDA experiment at FAIR. For the first time, high resolution gamma-spectroscopy of doubly strange Lambda Lambda-hypernuclei will be performed, thus complementing measurements of ground state decays of Lambda Lambda-hypernuclei at J-PARC or possible decays of particle unstable hypernuclei in heavy ion reactions. High resolution spectroscopy of multistrange Xi(-) -atoms will be feasible and even the production of Omega(-) -atoms will be within reach. The latter might open the door to the vertical bar S vertical bar = 3 world in strangeness nuclear physics, by the study of the hadronic Omega(-) -nucleus interaction. For the first time it will be possible to study the behavior of Xi(+) in nuclear systems under well controlled conditions. (C) 2016 Elsevier B.V. All rights reserved.

Published
2016
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114. Feasibility study for the measurement of πN transition distribution amplitudes at P¯ANDA in p¯p→J/ψπ0

Author

Tristan Weber, Michaela Thiel, T. Wasem, J. Schwiening, M. Kube, R. Schmitz, D. Lehmann, A. Trzcinski, A. Amoroso, A.A. Efremov, Alexander Olshevskiy, R. Klasen, Herbert Koch, M. Maggiora, A. Dbeyssi, Dipanwita Dutta, F. E. Maas, A. Chlopik, E. Etzelmüller, P. Wintz, V. Lucherini, P. Schakel, P. De Remigis, Krzysztof Swientek, G.S. Shabratova, H. Deppe, Angelo Rivetti, Riccardo Introzzi, K. Dutta, P. Wieczorek, V. M. Datar, W. Lauth, E. A. Strokovsky, L. Busso, M. Hoek, F. Balestra, G. Maniscalco, D. Khaneft, R. Schnell, S. Vejdani, N. G. Minaev, V. Chernetsky, B. Seitz, U. Thoma, K. K. Seth, Mario Bragadireanu, Amiran Tomaradze, B. Fröhlich, S. Pflüger, Valentino Rigato, Franco Bradamante, I. A. Kuyanov, E. Gutz, V. M. Abazov, D. P. Watts, Lennart Isaksson, M. Albrecht, V. Arefiev, T. Schröder, B. Singh, G. Sonika, A. Fechtchenko, C. Rosenbaum, L. Schmitt, Bernd Voss, B. Hetz, S. Sanchez, Magnus Wolke, S.A. Zaporozhets, A. Filippi, S. Coli, Bhavin Patel, A. Khoukaz, Markus Ball, A. Pitka, Krisztian Peters, B. Ramstein, K. Khosonthongkee, M. Pfaffinger, Torbjörn Bäck, D. Veretennikov, J. Pütz, R.A. Salmin, P. Balanutsa, B. J. Liu, A. Hayrapetyan, Chinorat Kobdaj, R. W. Novotny, P. Genova, W. Kühn, P. F. Dalpiaz, S. Belostotski, Ulrich Wiedner, A.S. Vodopianov, Yu.N. Rogov, Wojciech Krzemien, M. Wojciechowski, T. Erlen, Giuseppe Giraudo, B. Zwieglinski, H. Smit, E. Prencipe, J. Jaworowski, R.A. Kunne, S. Lusso, A.G. Fedunov, P. Musiol, C. Schnier, Yan Liang, H. Ohm, Paolo Montagna, A. Karavdina, G. Mazza, N. K. Walford, G. Boca, Boris Batyunya, M. Zyzak, V. Varentsov, M. Kuhlmann, M. Zühlsdorf, V. V. Tokmenin, G. Sterzenbach, M. Tiemens, Stanisław Kistryn, A. Kumar, Alessandro Bressan, F. Lisowski, Paul Alois Buhler, V. Carassiti, D. Prasuhn, M. Zambrana, R. Dzhygadlo, J. Lühning, M.K. Suleimanov, O. Noll, P. Salabura, M. Patsyuk, Christian Schmidt, Johann Zmeskal, M. Barnyakov, A. A. Piskun, F. Feldbauer, Susanna Costanza, Zbigniew Rudy, V. E. Blinov, F. De Mori, Alexander D. Vasiliev, V. Metag, C. Sfienti, Utpal Roy, E. Perevalova, M. Cardinali, R. Birsa, R. Teshev, Aleksandra Wrońska, Egle Tomasi-Gustafsson, F. Uhlig, K. Pysz, T. Sefzick, M. Steinen, V.B. Chandratre, M. Krebs, Matthias Richter, J. P. Wessels, W. Schäfer, M. Fritsch, M. Korjik, J. Rieke, Andreas Lehrach, M. Kavatsyuk, A. Kulkarni, R. F. Parodi, R. Karabowicz, A. Sanchez-Lorente, T.A. Pocheptsov, Valery Dormenev, A. Magiera, H. Flemming, Vassili Kachanov, K. Kalita, W. Erni, P. Poznański, T. Holtmann, O. Miklukho, J. Pychy, S. Bleser, Yu. Yu. Lobanov, Zhiqing Liu, T. Quagli, D. Branford, O. Corell, Konstantin Beloborodov, Dirk Grunwald, Jize Zhao, R. Böhm, L. Capozza, L. Ferrero, A. K. Hergemöller, T. Held, Mario Greco, A. Wilms, Alessandro Drago, I. Augustin, Mathias Fink, A. E. Yakutin, N. Belikov, D. I. Glazier, Sergey Nazarenko, D. Kang, A. Boukharov, M. Kesselkaul, V. Abramov, A. N. Skachkova, S. Bukreeva, U. Thöring, Hans-Georg Zaunick, A. Ryazantsev, S. Marcello, C. Guaraldo, V. Pothodi Chackara, K. Makonyi, A.I. Zinchenko, S. Ryzhikov, S. Orfanitski, Edward Lisowski, K. A. Martin, Ajit Kumar Mohanty, L. Lavezzi, Kirill M. Semenov-Tian-Shansky, S.A. Kononov, L. Gruber, Grzegorz Filo, M. Domagala, L. Cao, V. Di Pietro, S. Grieser, B. Ketzer, S. Schlimme, Marten Ole Schmidt, Alberto Rotondi, M. Michel, C. Schwarz, S. I. Manaenkov, E. A. Kravchenko, R. Beck, A. Gillitzer, Krzysztof Korcyl, B. Slowinski, G. Kesik, Felice Iazzi, U. Müller, D. Calvo, B. Krusche, C. Wang, M. Steinke, A. Gerhardt, V. L. Malyshev, I. Marishev, E. Widmann, Gianangelo Bracco, Harald Kleines, N. I. Zhuravlev, A. Lehmann, D. Nicmorus Marinescu, Patrick Achenbach, A. Apostolou, D. Walther, Johann Marton, C. Sowa, T. Saito, R. Dosdall, Ayut Limphirat, A. Belias, Dan Pantea, A. Täschner, A. Mustafa, D. Marchand, P. Kulessa, M. Galuska, C. Ugur, W. Ikegami Andersson, M. Savrie, C. Hammann, J. C. van der Weele, D. Wölbing, G.B. Pontecorvo, Vivekanand Jha, Hasko Stenzel, D. Przyborowski, P. Drexler, Antoni Szczurek, Tord Johansson, A. Gerasimov, T. Triffterer, A. Britting, S. Ahmed, Mihai Caprini, W. Eyrich, A. Kozela, V. Grishin, O. Malyshev, U. Kurilla, Yupeng Yan, H. Sohlbach, S. Leiber, P. Strzempek, X. Y. Shen, V. V. Mochalov, M. I. Martínez, U. Lynen, I. Lehmann, M. Bai, A. A. Zhdanov, M. Preston, M. Urban, M. Mikirtychyants, I. K. Keshk, Andrea Lavagno, Grzegorz Korcyl, H. Ahmadi, J. Biernat, A. Lai, M. Traxler, Richard Wheadon, M. Pelizäus, A. Cotta Ramusino, D. Rodríguez Piñeiro, Markus Büscher, R. Kliemt, M. M. Macri, V. Kormilitsin, A. Yu. Barnyakov, Z. Li, Ivan Kisel, Arpit Parmar, Tomasz Fiutowski, C. Schmidt, C. Morales Morales, J. Płażek, Michael Düren, Z. J. Sun, H. Loehner, M. Pugach, P. Fedorets, K. Suzuki, A. P. Onuchin, E. Fioravanti, Andrea Bianconi, B. Ma, Yu.M. Mel'nik, M. Deiseroth, F. H. Heinsius, D. G. Ireland, J. S. Lange, Anne-Laure Martin, B. Wohlfahrt, H. Xu, J. Van de Wiele, P. N. Deepak, D. A. Morozov, N. Hüsken, Livio Bianchi, Günter Kemmerling, S. Löchner, B. Galnander, Jifeng Hu, N. B. Skachkov, G. D. Alexeev, T. Ullrich, I. Zimmermann, B. J. Roy, E.K. Koshurnikov, D. Steinschaden, M. Michałek, Bruce Yabsley, M. N. Wagner, S. Wronka, Smbat Grigoryan, Paola Gianotti, Andrey V. Izotov, T. Kuske, S. C. Li, A. G. Zorin, A. Davidenko, M. Lindemulder, V. Astakhov, Andreas Herten, V.I. Lobanov, V.Kh. Dodokhov, Oleg V. Missevitch, Y. Wang, C. Hahn, A. Pyszniak, M.G. Sapozhnikov, L. V. Malinina, Andrey Uzunian, Andrei Fedorov, H. Orth, A. Ehret, Alastair J. Wilson, L. V. Nogach, R. Nellen, Hans Calén, I. Garzia, A.F. Makarov, Harphool Kumawat, S. I. Serednyakov, A. Galoyan, Paweł Moskal, Karin Schönning, W. Czyzycki, J. G. Messchendorp, A. Riccardi, M. Kümmel, A. Sokolov, Maria Krawczyk, Ting Xiao, S. Godre, A. G. Denig, Marek Idzik, M. O. Distler, Frank Goldenbaum, P. Srisawad, G. Kozlov, K. Biguenko, P.J.J. Lemmens, S. Spataro, M. Yu. Barabanov, S. Maldaner, A. Zambanini, Ajay Kumar Rai, I. Shein, M. Böhm, M. Rossbach, A. Demekhin, Yury Tikhonov, A. A. Derevschikov, C. Fritzsch, M. Babai, J. S. Díaz, V. K. Rodionov, A. E. Blinov, A. Cebulla, S. Reiter, A. Samartsev, Bartosz Mindur, V. N. Goryachev, H. B. Liu, B. Kopf, E. Atomssa, C. Wendel, Sean A Dobbs, J. Pochodzalla, Yu.I. Davydov, Genady Gavrilov, Andrew Levin, M.P. Bussa, G. Rosner, S. Jasper, Ankhi Roy, J. Olave, A. Bersani, Bo Cederwall, K. Götzen, B. Kamys, P. Wüstner, Piotr Lebiedowicz, D. Bettoni, A. Dolgolenko, P.-E. Tegnér, Mariana Nanova, D. Melnychuk, V. Akishina, P. A. Semenov, V. Balanutsa, P. Mahlberg, H. Leithoff, Victor Bobrovnikov, M. Papenbrock, L. Fava, R. Valente, R. Veenstra, C. Motzko, K.-T. Brinkmann, F. Nerling, V. Uzhinsky, Harald Merkel, M. Destefanis, D. Lin, Y.M. Goncharenko, M. C. Mora Espí, N. Divani Veis, Pawel Marciniewski, Mohammed Al-Turany, Q. Hu, Andrzej Kupsc, M. Steinacher, Tobias Stockmanns, J. Ritman, S. Diehl, V. Serdyuk, Jerzy Smyrski, A. Gromliuk, M. Mignone, M. Moritz, S. Sosio, S. Schadmand, G. Schepers, S. Poslavskiy, and Joachim Pettersson

Subjects
Quantum chromodynamics, Physics, Particle physics, Luminosity (scattering theory), Annihilation, Meson, 010308 nuclear & particles physics, 7. Clean energy, 01 natural sciences, Particle identification, Nuclear physics, Factorization, Antiproton, 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics, Bar (unit)
Abstract

The exclusive charmonium production process in (P) over barp annihilation with an associated pi 0 meson (p) over barp -> J/psi pi(0) is studied in the framework of QCD collinear factorization. The feasibility of measuring this reaction through the J/psi -> e(+) e(-) decay channel with the AntiProton ANnihilation at DArmstadt ((P) over bar ANDA) experiment is investigated. Simulations on signal reconstruction efficiency as well as the background rejection from various sources including the (P) over barp -> pi(+)pi(-)pi(0) and (p) over barp -> J/psi pi(0)pi(0) reactions are performed with PANDAROOT, the simulation and analysis software framework of the (P) over bar ANDA experiment. It is shown that the measurement can be done at (P) over bar ANDA with significant constraining power under the assumption of an integrated luminosity attainable in four to five months of data taking at the maximum design luminosity.

Published
2017
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115. Measurements and simulations of single-event upsets in a 28-nm FPGA

Author

M. Kavatsyuk, Hans Calén, K. Makonyi, Per Erik Tegner, M. Preston, P. Schakel, Pawel Marciniewski, Tord Johansson, and Research unit Nuclear & Hadron Physics

Subjects
Nuclear physics, Physics, Computer Science::Hardware Architecture, Electromagnetic calorimeter, Proton, Physics::Instrumentation and Detectors, Event (relativity), Nuclear Theory, Neutron, Nuclear Experiment, Field-programmable gate array
Abstract

Single-event upsets in the configuration memory of the 28-nm Xilinx Kintex-7 FPGA, used in the PANDA electromagnetic calorimeter, have been studied. Results from neutron and proton irradiations at energies up to 184 MeV are presented and compared with previous experimental results. In order to gain information about the energy-dependence of the single-event upset cross section, a GEANT4-based Monte Carlo simulation of upset mechanisms in nanometric silicon volumes has been developed. The results from this model are shown to agree with the experimental data for both neutrons and protons. Knowledge about the energy dependence of the cross section and of the particle flux at the location of the front-end modules in PANDA enables better estimates of the mean time between failures in the electromagnetic calorimeter. At PANDA, a total neutron flux of 1·102 cm− 2 s− 1 at the location of the front-end modules is expected at the lowest antipro-ton beam momentum and a luminosity of 1·1031 cm− 2 s− 1, leading to a predicted Mean Time Between Failures of 47±10 hours per FPGA in the electromagnetic calorimeter.

Published
2017
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116. Cognitive Assessment of Preschool Children.

Author

Schakel, Jacqueline A.

Abstract

The need for an ecological approach to cognitive assessment of preschool-aged children is discussed. Purposes of and popular approaches for cognitive assessment are presented. Tests and techniques are reviewed, and implications for the practice of psychology in the schools are discussed. (Author/LMO)

Published
1986

117. Noncategorical Identification of Preschool Handicapped Children: Policy Issues and Options.

Author

Smith, Barbara J. and Schakel, Jacqueline A.

Abstract

The article summarizes concurrent policy and practice concerning categorical and noncategorical diagnostic procedures for young handicapped children. The strengths and weaknesses of four noncategorical policy options are discussed. Potential misuses of noncategorical policies are reviewed, and recommendations for policy research are offered. (Author)

Published
1986

118. Definitions and Interventions for the Emotionally Disturbed in Alaska's Rural Schools.

Author

Bischoff, Herbert G. W. and Schakel, Jacqueline A.

Abstract

Concerns are cited regarding definitional, identification, and programing issues for emotionally disturbed students in rural Alaskan schools. Problems with the current state definition include its vagueness, reliance on noneducational experts, and implications that psychological or psychiatric treatment is necessary. Lack of resource room programing for emotionally disturbed children in the state is cited. Intervention guidelines are suggested for assessment/identification and placement/programing. (CL)

Published
1980

119. Continuing Education and School Psychology: A Review of State Requirements.

Author

Hynd, George W. and Schakel, Jacqueline A.

Abstract

Surveys state departments of education to determine present standards for continuing education of school psychologists. Of states responding 43 percent have some requirements; the majority require six semester hours of college credit within five years. The use of staff development credits includes workshops and conventions. (JAC)

Published
1981

120. Online cluster-finding algorithms for the PANDA electromagnetic calorimeter

Author

M. Kavatsyuk, M. Tiemens, and P. Schakel

Subjects
Event selection, Electromagnetic calorimeter, Data collection, Physics::Instrumentation and Detectors, Computer science, Electromagnetic compatibility, Cluster (physics), Cluster analysis, Field-programmable gate array, Algorithm, Implementation
Abstract

In this work, the performance of a proposed algorithm to search for clusters in the PANDA electromagnetic calorimeter (EMC) in real time, which provides vital information for the online event selection procedure, is discussed. Two implementations will be discussed and compared to each other and to a third, less suited algorithm (at least, as far as online usage is concerned). After this, the implementation in the readout hardware and concepts for the following data collection network will be presented.

Published
2016
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121. Narrow stack emissions: Errors in flow rate measurement due to disturbances and swirl

Author

Knotek, Stanislav, Workamp, Marcel, Geršl, Jan, and Schakel, Menne D.

Abstract

ABSTRACTEuropean legislation continues to drive down emission limit values, making the emission measurement of narrow stacks of increasing importance. However, the applicable standards (EN ISO 16911–1 and EN 15259) are poorly validated for narrow stacks, and the effect of flow disturbances on the described methods are largely unknown. In this article, measurement errors are investigated in narrow stacks with flow disturbances and swirl, both experimentally and through computational fluid dynamics (CFD) simulations. The results indicate that measurement errors due to misalignment of the flow with typical measuring probes (pitot tubes) are small compared to errors resulting from the positioning of these probes in the measurement plane. Errors up to 15% are reported using the standardized methods, while the measurement error is both smaller and more predictable when using additional measurement points.Implications: Current international standards provide methods to measure emissions from industrial stacks. With increasingly small emission limit values, the accuracy of these measurements is becoming considerably more important. The data from this study can be used to inform revisions of these standards, in particular with respect to flow disturbances in narrow stacks, and can help law- and policy-makers to obtain insight into the uncertainties of emission measurements in these specific situations.

Published
2021
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122. Video-rate scanning probe control challenges: setting the stage for a microscopy revolution

Author

W. A. van Loo, P. Schakel, Joost W. M. Frenken, G. J. C. van Baarle, W. M. van Spengen, Tjerk H. Oosterkamp, Allard J. Katan, and M. J. Rost

Subjects
Engineering, Scanning Hall probe microscope, Scanner, Microscope, business.industry, Engineering physics, Piezoelectricity, law.invention, Scanning probe microscopy, Acceleration, Control and Systems Engineering, law, Microscopy, Scanning tunneling microscope, business
Abstract

Scanning probe microscopy is at the verge of revolutionizing microscopy once again. Video-rate scanning tunneling microscope (STM) and video-rate atomic force microscope (AFM) technology will enable the direct observation of many dynamic processes that are impossible to observe today, such as atom or molecule diffusion, real time film growth, or catalytic reactions. In this paper we discuss the critical aspects that have to be taken into account when working on increasing the imaging speed of scanning probe microscopes. We highlight the state-of-the-art developments in the control of the piezoelectric scanning elements and describe the latest innovations regarding the design and construction of the whole mechanical loop including new scanner geometries. We identify critical aspects for which no obvious solution exists and aspects where advanced control engineering can help, like piezo non-linearities, the acceleration limit and the challenging technical requirements for the preamplifiers that are needed for measuring a tunneling current. Finally, we provide an overview of a number of new directions that are being pursued to solve the problems currently encountered in scanning probe technology.

Published
2009
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123. Experimental access to Transition Distribution Amplitudes with the P̄ANDA experiment at FAIR

Author

M. C. Mora Espí, Pawel Marciniewski, K. Makonyi, Yupeng Yan, S. Wronka, D. Pietreanu, Shaji Kumar, N. Belikov, D. I. Glazier, A. Gillitzer, K. Khanchai, Ajay Kumar Rai, M. Steinen, D. Calvo, Yury Tikhonov, A. A. Derevschikov, T. A. Pocheptsov, R.A. Salmin, P. Balanutsa, B. J. Liu, P. N. Deepak, A. E. Blinov, S. Lange, S. Ryzhikov, G. Kalicy, Arpit Parmar, P. Musiol, G. D. Alexeev, D. P. Watts, Lennart Isaksson, Tobias Stockmanns, E. Gutz, P. F. Dalpiaz, Zhi Liu, D. Marchand, S. Grieser, A. Gerhardt, D. Kangh, L. Fava, A. A. Festchenko, Harphool Kumawat, I. Zimmermann, M. Albrecht, B. Krusche, A. Sanchez Lorente, E. A. Strokovsky, M. A. Pasyuk, J. Ritman, P. C. Vinodkumar, T. Quagli, M.G. Sapozhnikov, Ashok Kumar, Herbert Koch, V. I. Astakhov, V. Serdyuk, K. M. von Würtemberg, D. Münchow, Hans-Georg Zaunick, S. Marcello, M. Ullrich, A. Mustafa, Paola Gianotti, T. Kuske, Michaela Thiel, Kamal K. Seth, S. Schlimme, C. Schwarz, M. Savrie, B. Ketzer, Jerzy Smyrski, E. Etzelmüller, A. G. Fedunov, H. Sohlbach, K. Malgorzata, Victor Bobrovnikov, R.Sh. Teshev, L. Ayut, V.M. Abazov, B. Spruck, B. Kamys, D. Mülhheim, Krzysztof Swientek, S. Schadmand, M. V. Korzihik, Zbigniew Rudy, Matei Eugen Vasile, T. Wasem, J. Schwiening, D. Lehmann, M. Patsyuk, Karin Schönning, W. Czyzycki, M. Zühlsdorf, V. N. Goryachev, A. G. Zorin, A. Davidenko, W. Lauth, B. Fröhlich, A. Amoroso, V. Lucherini, P. Schakel, Grzegorz Korcyl, G.A. Mustafaev, Smbat Grigoryan, Ajit Kumar Mohanty, Grzegorz Filo, R. Veenstra, P. Wüstner, J. Marton, Boris Batyunya, L. Ferrero, A. N. Skachkova, Edward Lisowski, I. Garzia, D. Bremer, T. Eissner, D. Lin, Y.M. Goncharenko, Soumen Paul, A.A. Efremov, Dipanwita Dutta, Alberto Rotondi, M. Michel, B. Slowinski, A. Arefiev, Philip Woods, I. Augustin, Yan Liang, A. Karavdina, M. Greco, P. Rosier, Antoni Szczurek, N. Saito, K. Föhl, T. Schröder, B. Singh, Mariana Nanova, Andreas Herten, Oleg V. Missevitch, S.A. Zaporozhets, K.-T. Brinkmann, Sukanta Dash, A. Filippi, A. Trzcinski, Marek Idzik, M. O. Distler, J. Schumann, C. Sowa, I. Konorov, J. C. van der Weele, Mathias Fink, A. E. Yakutin, B. Kopf, E. Atomssa, A. Pitka, R. Karabowicz, H. H. Leithoff, Angelo Rivetti, S. Pornrad, S. Diehl, M. Maggiora, B. Kröck, R. Duchat, O. Levitskaya, Gianluigi Boca, Krzysztof Korcyl, Gianangelo Bracco, Harald Kleines, F. Nerling, L. Caldeira Balkeståhl, S. Coli, E. Perevalova, T. Gessler, Klaus Peters, A. Magiera, Vassili Kachanov, M. Hawryluk, S. Ong, R. Varma, X. Shen, T. Czyzewski, M. Domagala, S. Godre, M. Zyzak, J. Pettersson, F. Uhlig, F. De Mori, P.J.J. Lemmens, Alexander D. Vasiliev, Mohammed Al-Turany, Q. Hu, Andrzej Kupsc, R. Schmitz, P. Mahlberg, P. De Remigis, C. Schnier, S. Lusso, R. Dosdall, L. Zotti, J. Van de Wiele, A. Britting, S. Fissum, Zhigang Li, Jozef Zlomanczuk, Amiran Tomaradze, S. Spataro, U. Müller, R. Valente, V. Uzhinsky, Giulio Stancari, G. S. Shabratova, I. Keshelashvili, S. Jowzaee, Harald Merkel, C. Guaraldo, S. Li, Christian Schmidt, M. Steinacher, V. Kozlov, Yu.N. Rogov, A. Bianconi, T. Held, V. Datar, Andrei Fedorov, H. Orth, T. Weber, A. Kozela, Piotr Salabura, M. Destefanis, Andrea Lavagno, M. Kuhlmann, B. Ma, J. Pychy, Piotr Lebiedowicz, L. Capozza, Dominik Kwiatkowski, Andrew Levin, A. Wilms, Germán Mazza, Matthias Richter, Wojciech Krzemien, Sean A Dobbs, J. Pochodzalla, I. Shein, H. Ohm, Paolo Montagna, Paul Alois Buhler, Y. Naryshkin, Hans Calén, A. Apostolou, S. Orfanitski, V. Grishin, A. Kashchuk, V. Kormilitsin, Tomasz Fiutowski, M. Mingnore, M. Krebs, A. Dolgolenko, E. Fioravanti, P.-E. Tegnér, A. Chlopik, A. Gromliuk, Andreas Lehrach, I. Georgadze, B. Czech, B. Zwieglinski, Kurt Hansen, W. Schäfer, C. Motzko, R. Kunne, P. Genova, J. Lühning, A. Psyzniak, S. Bianco, H. Smit, Nicola Bianchi, Felice Iazzi, J. Rieke, M. Fritsch, R. Dzhygadlo, O. Corell, E. Pace, S. I. Manaenkov, V. Chandratre, S. Sosio, A. Olshevskiy, T. Johansson, S. Sanchez, Concettina Sfienti, R. F. Parodi, D. Walther, T. Saito, E. Köhler, Zhi Sun, Markus Büscher, P. Kulessa, Magnus Wolke, I. Kisel, V. Tokmenin, Alexander Vodopyanov, J.H. Zhao, C. Wang, M. Kube, M. Kavatsyuk, T. Hennino, Johann Zmeskal, V. Varentsov, C. Morales Morales, S. Esch, R. Kliemt, G. Schepers, S. Poslavskiy, Alessandro Drago, Dan Pantea, M. Imre, W. Eyrich, D. Melnychuk, M.P. Bussa, Dirk Grunwald, I. Lehmann, D. Rodríguez Piñeiro, Kjell Fransson, A. P. Onuchin, Valery Dormenev, M. Rossbach, F. E. Maas, Giuseppe Giraudo, M. Pelizäus, D. P. Mohanta, H. Deppe, C. Rosenbaum, M. Cardinali, A. G. Denig, A. Boukharov, V. Abramov, A. Hayrapetyan, K. Pysz, Vladimir Blinov, A. K. Hergemöller, A. Ryazantsev, K. Kalita, P. Wintz, Raghunath Sahoo, V. Akishina, P. A. Semenov, V. Balanutsa, Mikael Lundin, M. M. Macri, Anne-Laure Martin, A. Karmokov, U. Cahit, A. Demekhin, G. Rosner, W. Erni, S. Plueger, S. Leiber, Michael Werner, L. Schmitt, S. Costanza, Bent Schröder, R. Arora, D. Deermann, M. Leyhe, S.A. Kononov, S. Belostotski, Ulrich Wiedner, Maria Krawczyk, L. V. Malinina, M. Tiemens, Yu.M. Mel'nik, Ch. Schmidt, O. Merle, U. Thoma, M. Babai, A. Semenov, R. Maier, Ankhi Roy, Michael Düren, L. V. Nogach, E. Widmann, A. Zhadanov, Valentino Rigato, Stanisław Kistryn, P. Fedorets, K. Suzuki, D. A. Morozov, Franco Bradamante, Torbjörn Bäck, L. Busso, C. Le Galliard, Bhavin Patel, Alessandro Bressan, K. Chinorat, M. Wojciechowski, A. Lehmann, A.F. Makarov, A. Galoyan, P. Wieczorek, T. Holtmann, Bernd Voss, Aleksandra Wrońska, J. S. Díaz, M. Hoek, D. Veretennikov, F. H. Heinsius, P. Brandys, F. Balestra, H. Flemming, F. Lisowski, H. Younis, Paweł Moskal, G. Maniscalco, P. Jasinski, V. K. Rodionov, J. G. Messchendorp, R. Schnell, O. Miklukho, D. Prasuhn, M. Zambrana, M. Kümmel, L. Cao, I. Marishev, A. Bersani, Bo Cederwall, K. Götzen, L. Lavezzi, S. Vejdani, N. G. Minaev, Herbert Löhner, V. Metag, R. W. Novotny, E. Tomasi-Gustafsson, N. B. Skachkov, A. Cebulla, Bartosz Mindur, V. Chernetsky, B. Seitz, Daniel M. Kaplan, E. K. Koshurnikov, B. Ramstein, A. Kulkarni, B. J. Roy, T. Sefzick, D. Khaneft, D. Branford, A. A. Piskun, Reinhard Beck, S. Bleser, Yu. Yu. Lobanov, R. Siudak, V. I. Lobanov, E. A. Kravchenko, S. Bukreeva, A. Samartsev, U. Thöring, F. Feldbauer, Ting Xiao, Patrick Achenbach, Hongwei Liu, Johannes Peter Wessels, D. Bettoni, Yu.I. Davydov, V. I. Dormenev, Genady Gavrilov, Ch. Wendel, M. Yu. Barabanov, Kirill M. Semenov-Tian-Shansky, R. Birsa, T. Bel, Günter Kemmerling, A. Khoukaz, V. Carassiti, B. Galnander, Jifeng Hu, M. Bragadireanu, I. A. Kuyanov, Bruce Yabsley, Andrey V. Izotov, O. Noll, J. Kunkel, A. Dbeyssi, K. Suvorov, Vivekanand Jha, Wolfgang Kuhn, Hasko Stenzel, O. Malyshev, A. A. Sokolov, U. Kurilla, G. Kuhl, D. Kaiser, P. Strzempek, A. Goerres, J. Biernat, D. G. Ireland, H. Xu, M. K. Suleimanov, G. Sterzenbach, E. Prencipe, A. Ortiz, N. I. Zhuravlev, A. Täschner, A. Gerasimov, T. Triffterer, M. Deiseroth, A. Wilson, Marek Palka, M. Lindemulder, A. Y. Barnyakov, V.Kh. Dodokhov, D. Nicmorus, Andrey Uzunian, A. Ehret, R. Nellen, Ch. Hammann, M. Steinke, V. L. Malyshev, P. Drexler, Richard Wheadon, A. Cotta Ramusino, P. Sarin, Riccardo Introzzi, H. Clement, I. Kulakov, M. Zuehlsdorf, M. Galuska, S. Kliczewski, G.B. Pontecorvo, D. Przyborowski, Mihai Caprini, V. V. Mochalov, M. Jadhav, M. Mikirtychyants, M. Traxler, Frank Goldenbaum, Research unit Nuclear & Hadron Physics, The PANDA Collaboration, Null, Singh, B. P, Erni, W., Keshelashvili, I., Krusche, B., Steinacher, M., Liu, B., Liu, H., Liu, Z., Shen, X., Wang, C., Zhao, J., Albrecht, M., Fink, M., Heinsius, F. H., Held, T., Holtmann, T., Koch, H., Kopf, B., Kümmel, M., Kuhl, G., Kuhlmann, M., Leyhe, M., Mikirtychyants, M., Musiol, P., Mustafa, A., Pelizäus, M., Pychy, J., Richter, M., Schnier, C., Schröder, T., Sowa, C., Steinke, M., Triffterer, T., Wiedner, U., Beck, R., Hammann, C., Kaiser, D., Ketzer, B., Kube, M., Mahlberg, P., Rossbach, M., Schmidt, C., Schmitz, R., Thoma, U., Walther, D., Wendel, C., Wilson, A., Bianconi, A., Bragadireanu, M., Caprini, M., Pantea, D., Pietreanu, D., Vasile, M. E., Patel, B., Kaplan, D., Brandys, P., Czyzewski, T., Czyzycki, W., Domagala, M., Hawryluk, M., Filo, G., Krawczyk, M., Kwiatkowski, D., Lisowski, E., Lisowski, F., Fiutowski, T., Idzik, M., Mindur, B., Przyborowski, D., Swientek, K., Czech, B., Kliczewski, S., Korcyl, K., Kozela, A., Kulessa, P., Lebiedowicz, P., Malgorzata, K., Pysz, K., Schäfer, W., Siudak, R., Szczurek, A., Biernat, J., Jowzaee, S., Kamys, B., Kistryn, S., Korcyl, G., Krzemien, W., Magiera, A., Moskal, P., Palka, M., Psyzniak, A., Rudy, Z., Salabura, P., Smyrski, J., Strzempek, P., Wrońska, A., Augustin, I., Lehmann, I., Nicmorus, D., Schepers, G., Schmitt, L., Al Turany, M., Cahit, U., Capozza, L., Dbeyssi, A., Deppe, H., Dzhygadlo, R., Ehret, A., Flemming, H., Gerhardt, A., Götzen, K., Karabowicz, R., Kliemt, R., Kunkel, J., Kurilla, U., Lehmann, D., Lühning, J., Maas, F., Morales Morales, C., Mora Espí, M. C., Nerling, F., Orth, H., Peters, K., Rodríguez Piñeiro, D., Saito, N., Saito, T., Sánchez Lorente, A., Schmidt, C. J., Schwarz, C., Schwiening, J., Traxler, M., Valente, R., Voss, B., Wieczorek, P., Wilms, A., Zühlsdorf, M., Abazov, V. M., Alexeev, G., Arefiev, A., Astakhov, V. I., Barabanov, M. Y. u., Batyunya, B. V., Davydov, Y. u. I., Dodokhov, V. K. h., Efremov, A. A., Fedunov, A. G., Festchenko, A. A., Galoyan, A. S., Grigoryan, S., Karmokov, A., Koshurnikov, E. K., Lobanov, V. I., Lobanov, Y. u. Y. u., Makarov, A. F., Malinina, L. V., Malyshev, V. L., Mustafaev, G. A., Olshevskiy, A., Pasyuk, M. A., Perevalova, E. A., Piskun, A. A., Pocheptsov, T. A., Pontecorvo, G., Rodionov, V. K., Rogov, Y. u. N., Salmin, R. A., Samartsev, A. G., Sapozhnikov, M. G., Shabratova, G. S., Skachkov, N. B., Skachkova, A. N., Strokovsky, E. A., Suleimanov, M. K., Teshev, R. S. h., Tokmenin, V. V., Uzhinsky, V. V., Vodopyanov, A. S., Zaporozhets, S. A., Zhuravlev, N. I., Zorin, A. G., Branford, D., Glazier, D., Watts, D., Woods, P., Britting, A., Eyrich, W., Lehmann, A., Uhlig, F., Dobbs, S., Seth, K., Tomaradze, A., Xiao, T., Bettoni, D., Carassiti, V., Cotta Ramusino, A., Dalpiaz, P., Drago, A., Fioravanti, E., Garzia, I., Savriè, M., Stancari, G., Akishina, V., Kisel, I., Kulakov, I., Zyzak, M., Arora, R., Bel, T., Gromliuk, A., Kalicy, G., Krebs, M., Patsyuk, M., Zuehlsdorf, M., Bianchi, N., Gianotti, P., Guaraldo, C., Lucherini, V., Pace, E., Bersani, A., Bracco, G., Macri, M., Parodi, R. F., Bianco, S., Bremer, D., Brinkmann, K. T., Diehl, S., Dormenev, V., Drexler, P., Düren, M., Eissner, T., Etzelmüller, E., Föhl, K., Galuska, M., Gessler, T., Gutz, E., Hayrapetyan, A., Hu, J., Kröck, B., Kühn, W., Kuske, T., Lange, S., Liang, Y., Merle, O., Metag, V., Mülhheim, D., Münchow, D., Nanova, M., Novotny, R., Pitka, A., Quagli, T., Rieke, J., Rosenbaum, C., Schnell, R., Spruck, B., Stenzel, H., Thöring, U., Ullrich, M., Wasem, T., Werner, M., Zaunick, H. G., Ireland, D., Rosner, G., Seitz, B., Deepak, P. N., Kulkarni, A. V., Apostolou, A., Babai, M., Kavatsyuk, M., Lemmens, P., Lindemulder, M., Löhner, H., Messchendorp, J., Schakel, P., Smit, H., van der Weele, J. C., Tiemens, M., Veenstra, R., Vejdani, S., Kalita, K., Mohanta, D. P., Kumar, A., Roy, A., Sahoo, R., Sohlbach, H., Büscher, M., Cao, L., Cebulla, A., Deermann, D., Dosdall, R., Esch, S., Georgadze, I., Gillitzer, A., Goerres, A., Goldenbaum, F., Grunwald, D., Herten, A., Hu, Q., Kemmerling, G., Kleines, H., Kozlov, V., Lehrach, A., Leiber, S., Maier, R., Nellen, R., Ohm, H., Orfanitski, S., Prasuhn, D., Prencipe, E., Ritman, J., Schadmand, S., Schumann, J., Sefzick, T., Serdyuk, V., Sterzenbach, G., Stockmanns, T., Wintz, P., Wüstner, P., Xu, H., Li, S., Li, Z., Sun, Z., Rigato, V., Fissum, S., Hansen, K., Isaksson, L., Lundin, M., Schröder, B., Achenbach, P., Bleser, S., Cardinali, M., Corell, O., Deiseroth, M., Denig, A., Distler, M., Feldbauer, F., Fritsch, M., Jasinski, P., Hoek, M., Kangh, D., Karavdina, A., Lauth, W., Leithoff, H., Merkel, H., Michel, M., Motzko, C., Müller, U., Noll, O., Plueger, S., Pochodzalla, J., Sanchez, S., Schlimme, S., Sfienti, C., Steinen, M., Thiel, M., Weber, T., Zambrana, M., Dormenev, V. I., Fedorov, A. A., Korzihik, M. V., Missevitch, O. V., Balanutsa, P., Balanutsa, V., Chernetsky, V., Demekhin, A., Dolgolenko, A., Fedorets, P., Gerasimov, A., Goryachev, V., Varentsov, V., Boukharov, A., Malyshev, O., Marishev, I., Semenov, A., Konorov, I., Paul, S., Grieser, S., Hergemöller, A. K., Khoukaz, A., Köhler, E., Täschner, A., Wessels, J., Dash, S., Jadhav, M., Kumar, S., Sarin, P., Varma, R., Chandratre, V. B., Datar, V., Dutta, D., Jha, V., Kumawat, H., Mohanty, A. K., Roy, B., Yan, Y., Chinorat, K., Khanchai, K., Ayut, L., Pornrad, S., Barnyakov, A. Y., Blinov, A. E., Blinov, V. E., Bobrovnikov, V. S., Kononov, S. A., Kravchenko, E. A., Kuyanov, I. A., Onuchin, A. P., Sokolov, A. A., Tikhonov, Y. A., Atomssa, E., Hennino, T., Imre, M., Kunne, R., Le Galliard, C., Ma, B., Marchand, D., Ong, S., Ramstein, B., Rosier, P., Tomasi Gustafsson, E., Van de Wiele, J., Boca, G., Costanza, S., Genova, P., Lavezzi, L., Montagna, P., Rotondi, A., Abramov, V., Belikov, N., Bukreeva, S., Davidenko, A., Derevschikov, A., Goncharenko, Y., Grishin, V., Kachanov, V., Kormilitsin, V., Melnik, Y., Levin, A., Minaev, N., Mochalov, V., Morozov, D., Nogach, L., Poslavskiy, S., Ryazantsev, A., Ryzhikov, S., Semenov, P., Shein, I., Uzunian, A., Vasiliev, A., Yakutin, A., Yabsley, B., Bäck, T., Cederwall, B., Makónyi, K., Tegnér, P. E., von Würtemberg, K. M., Belostotski, S., Gavrilov, G., Izotov, A., Kashchuk, A., Levitskaya, O., Manaenkov, S., Miklukho, O., Naryshkin, Y., Suvorov, K., Veretennikov, D., Zhadanov, A., Rai, A. K., Godre, S. S., Duchat, R., Amoroso, A., Bussa, M. P., Busso, L., De Mori, F., Destefanis, M., Fava, L., Ferrero, L., Greco, M., Maggiora, M., Maniscalco, G., Marcello, S., Sosio, S., Spataro, S., Zotti, L., Calvo, D., Coli, S., De Remigis, P., Filippi, A., Giraudo, G., Lusso, S., Mazza, G., Mingnore, M., Rivetti, A., Wheadon, R., Balestra, F., Iazzi, F., Introzzi, R., Lavagno, A., Younis, H., Birsa, Renato, Bradamante, Franco, Bressan, Andrea, Martin, Anna, Clement, H., Gålnander, B., Caldeira Balkeståhl, L., Calén, H., Fransson, K., Johansson, T., Kupsc, A., Marciniewski, P., Pettersson, J., Schönning, K., Wolke, M., Zlomanczuk, J., Díaz, J., Ortiz, A., Vinodkumar, P. C., Parmar, A., Chlopik, A., Melnychuk, D., Slowinski, B., Trzcinski, A., Wojciechowski, M., Wronka, S., Zwieglinski, B., Bühler, P., Marton, J., Suzuki, K., Widmann, E., Zmeskal, J., Fröhlich, B., Khaneft, D., Lin, D., Zimmermann, I., and Semenov Tian Shansky, K.

Subjects
Particle physics, (P)Over-Baranda, Nuclear and High Energy Physics, Electroproduction, Hadron, Annihilation, FOS: Physical sciences, 7. Clean energy, 01 natural sciences, Particle identification, Nucleon, NO, Nuclear physics, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), Factorization, 0103 physical sciences, Fysik, Invariant mass, ddc:530, Meson Production, Monte-Carlo, Nuclear Experiment (nucl-ex), 010306 general physics, Nuclear Experiment, Physics, Quantum chromodynamics, 010308 nuclear & particles physics, Perturbative QCD, Qcd, Physical Sciences, Exclusive Processes, High Energy Physics::Experiment, Pi(0), Cross-Sections, Energy (signal processing)
Abstract

Baryon-to-meson Transition Distribution Amplitudes (TDAs) encoding valuable new information on hadron structure appear as building blocks in the collinear factorized description for several types of hard exclusive reactions. In this paper, we address the possibility of accessing nucleon-to-pion ($��N$) TDAs from $\bar{p}p \to e^+e^- ��^0$ reaction with the future PANDA detector at the FAIR facility. At high center of mass energy and high invariant mass squared of the lepton pair $q^2$, the amplitude of the signal channel $\bar{p}p \to e^+e^- ��^0$ admits a QCD factorized description in terms of $��N$ TDAs and nucleon Distribution Amplitudes (DAs) in the forward and backward kinematic regimes. Assuming the validity of this factorized description, we perform feasibility studies for measuring $\bar{p}p \to e^+e^- ��^0$ with the PANDA detector. Detailed simulations on signal reconstruction efficiency as well as on rejection of the most severe background channel, i.e. $\bar{p}p \to ��^+��^- ��^0$ were performed for the center of mass energy squared $s = 5$ GeV$^2$ and $s = 10$ GeV$^2$, in the kinematic regions $3.0 < q^2 < 4.3$ GeV$^2$ and $5 < q^2 < 9$ GeV$^2$, respectively, with a neutral pion scattered in the forward or backward cone $| \cos��_{��^0}| > 0.5 $ in the proton-antiproton center of mass frame. Results of the simulation show that the particle identification capabilities of the PANDA detector will allow to achieve a background rejection factor of $5\cdot 10^7$ ($1\cdot 10^7$) at low (high) $q^2$ for $s=5$ GeV$^2$, and of $1\cdot 10^8$ ($6\cdot 10^6$) at low (high) $q^2$ for $s=10$ GeV$^2$, while keeping the signal reconstruction efficiency at around $40\%$. At both energies, a clean lepton signal can be reconstructed with the expected statistics corresponding to $2$ fb$^{-1}$ of integrated luminosity. (.../...), 19 pages, 7 figures (some multiple), 2 tables (each double), preprint of an article for epj - v2

Published
2015
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124. Trigger-less readout system with pulse pile-up recovery for the PANDA electromagnetic calorimeter

Author

F. Schreuder, R. Speelman, G. Tambave, P. Schakel, P.J.J. Lemmens, Herbert Löhner, M. Kavatsyuk, M. Hevinga, KVI - Center for Advanced Radiation Technology, and Research unit Nuclear & Hadron Physics

Subjects
Physics, Nuclear and High Energy Physics, Spectrometer, business.industry, Physics::Instrumentation and Detectors, Digital filtering, Dead time, Trigger-less readout, Signal, Synchronization, ELECTRONICS, Data acquisition, Pile-up recovery, Sampling (signal processing), Electromagnetic calorimeter, Sampling ADC, Feature extraction, Electronics, business, Field-programmable gate array, Instrumentation, Computer hardware
Abstract

A simple, efficient, and robust on-line data-processing scheme was developed for the digital front-end electronics of the electromagnetic calorimeter of the PANDA spectrometer at FAIR, Darmstadt. The implementation of the processing algorithm in FPGA enables the construction of an almost dead-time free data acquisition system. The prototype of a complete trigger-less readout chain has been developed and evaluated. The precision of time synchronisation commands has been verified. A pile-up recovery algorithm was developed and evaluated over a large dynamic range of signal amplitudes. (C) 2012 Elsevier B.V. All rights reserved.

Published
2013

125. Improving the accuracy of walking piezo motors

Author

Amirmehdi Saedi, M. den Heijer, M. J. Rost, P. Schakel, and V. Fokkema

Subjects
Computer science, Piezoelectric motor, law, Acoustics, Range (aeronautics), Measure (physics), Movement (clockwork), Rigidity (psychology), Scanning tunneling microscope, Actuator, Instrumentation, Displacement (vector), law.invention
Abstract

Many application areas require ultraprecise, stiff, and compact actuator systems with a high positioning resolution in combination with a large range as well as a high holding and pushing force. One promising solution to meet these conflicting requirements is a walking piezo motor that works with two pairs of piezo elements such that the movement is taken over by one pair, once the other pair reaches its maximum travel distance. A resolution in the pm-range can be achieved, if operating the motor within the travel range of one piezo pair. However, applying the typical walking drive signals, we measure jumps in the displacement up to 2.4 μm, when the movement is given over from one piezo pair to the other. We analyze the reason for these large jumps and propose improved drive signals. The implementation of our new drive signals reduces the jumps to less than 42 nm and makes the motor ideally suitable to operate as a coarse approach motor in an ultra-high vacuum scanning tunneling microscope. The rigidity of the motor is reflected in its high pushing force of 6.4 N.

Published
2014

128. Technical design report for the $\overline{P}$ ANDA (AntiProton Annihilations at Darmstadt) Straw Tube Tracker

Author

W. Erni, I. Keshelashvili, B. Krusche, M. Steinacher, Y. Heng, Z. Liu, H. Liu, X. Shen, Q. Wang, H. Xu, A. Aab, M. Albrecht, J. Becker, A. Csapó, F. Feldbauer, M. Fink, P. Friedel, F. H. Heinsius, T. Held, L. Klask, H. Koch, B. Kopf, S. Leiber, M. Leyhe, C. Motzko, M. Pelizäus, J. Pychy, B. Roth, T. Schröder, J. Schulze, C. Sowa, M. Steinke, T. Trifterer, U. Wiedner, J. Zhong, R. Beck, S. Bianco, K. T. Brinkmann, C. Hammann, F. Hinterberger, D. Kaiser, R. Kliemt, M. Kube, A. Pitka, T. Quagli, C. Schmidt, R. Schmitz, R. Schnell, U. Thoma, P. Vlasov, D. Walther, C. Wendel, T. Würschig, H. G. Zaunick, A. Bianconi, M. Bragadireanu, M. Caprini, D. Pantea, D. Pantelica, D. Pietreanu, L. Serbina, P. D. Tarta, D. Kaplan, T. Fiutowski, M. Idzik, B. Mindur, D. Przyborowski, K. Swientek, B. Czech, M. Kistryn, S. Kliczewski, A. Kozela, P. Kulessa, P. Lebiedowicz, K. Pysz, W. Schäfer, R. Siudak, A. Szczurek, S. Jowzaee, M. Kajetanowicz, B. Kamys, S. Kistryn, G. Korcyl, K. Korcyl, W. Krzemien, A. Magiera, P. Moskal, M. Palka, Z. Rudy, P. Salabura, J. Smyrski, A. Wrońska, I. Augustin, I. Lehmann, D. Nimorus, G. Schepers, M. Al-Turany, R. Arora, H. Deppe, H. Flemming, A. Gerhardt, K. Götzen, A. F. Jordi, G. Kalicy, R. Karabowicz, D. Lehmann, B. Lewandowski, J. Lühning, F. Maas, H. Orth, M. Patsyuk, K. Peters, T. Saito, C. J. Schmidt, L. Schmitt, C. Schwarz, J. Schwiening, M. Traxler, B. Voss, P. Wieczorek, A. Wilms, M. Zühlsdorf, V. M. Abazov, G. Alexeev, A. Arefiev, V. I. Astakhov, M. Yu. Barabanov, B. V. Batyunya, Yu. I. Davydov, V. Kh. Dodokhov, A. A. Efremov, A. G. Fedunov, A. A. Festchenko, A. S. Galoyan, S. Grigoryan, A. Karmokov, E. K. Koshurnikov, V. I. Lobanov, Yu. Yu. Lobanov, A. F. Makarov, L. V. Malinina, V. L. Malyshev, G. A. Mustafaev, A. Olshevskiy, M. A. Pasyuk, E. A. Perevalova, A. A. Piskun, T. A. Pocheptsov, G. Pontecorvo, V. K. Rodionov, Yu. N. Rogov, R. A. Salmin, A. G. Samartsev, M. G. Sapozhnikov, G. S. Shabratova, A. N. Skachkova, N. B. Skachkov, E. A. Strokovsky, M. K. Suleimanov, R. Sh. Teshev, V. V. Tokmenin, V. V. Uzhinsky, A. S. Vodopyanov, S. A. Zaporozhets, N. I. Zhuravlev, A. G. Zorin, D. Branford, D. Glazier, D. Watts, P. Woods, A. Britting, W. Eyrich, A. Lehmann, F. Uhlig, S. Dobbs, Z. Metreveli, K. Seth, A. Tomaradze, T. Xiao, D. Bettoni, V. Carassiti, A. Cotta Ramusino, P. Dalpiaz, A. Drago, E. Fioravanti, I. Garzia, M. Savriè, G. Stancari, N. Bianchi, P. Gianotti, C. Guaraldo, V. Lucherini, D. Orecchini, E. Pace, A. Bersani, G. Bracco, M. Macri, R. F. Parodi, D. Bremer, V. Dormenev, P. Drexler, M. Düren, T. Eissner, K. Föhl, M. Galuska, T. Gessler, A. Hayrapetyan, J. Hu, P. Koch, B. Kröck, W. Kühn, S. Lange, Y. Liang, O. Merle, V. Metag, M. Moritz, D. Münchow, M. Nanova, R. Novotny, B. Spruck, H. Stenzel, T. Ullrich, M. Werner, C. Euan, M. Hoek, D. Ireland, T. Keri, R. Montgomery, D. Protopopescu, G. Rosner, B. Seitz, M. Babai, A. Glazenborg-Kluttig, M. Kavatsyuk, P. Lemmens, M. Lindemulder, H. Löhner, J. Messchendorp, H. Moeini, P. Schakel, F. Schreuder, H. Smit, G. Tambave, J. C. van der Weele, R. Veenstra, H. Sohlbach, M. Büscher, D. Deermann, R. Dosdall, S. Esch, A. Gillitzer, F. Goldenbaum, D. Grunwald, S. Henssler, A. Herten, Q. Hu, G. Kemmerling, H. Kleines, V. Kozlov, A. Lehrach, R. Maier, M. Mertens, H. Ohm, S. Orfanitski, D. Prasuhn, T. Randriamalala, J. Ritman, M. Röder, S. Schadmand, V. Serdyuk, G. Sterzenbach, T. Stockmanns, P. Wintz, P. Wüstner, J. Kisiel, S. Li, Z. Li, Z. Sun, V. Rigato, S. Fissum, K. Hansen, L. Isaksson, M. Lundin, B. Schröder, P. Achenbach, S. Bleser, U. Cahit, M. Cardinali, A. Denig, M. Distler, M. Fritsch, P. Jasinski, D. Kangh, A. Karavdina, W. Lauth, H. Merkel, M. Michel, M. C. Mora Espi, U. Müller, J. Pochodzalla, S. Sanchez, A. Sanchez-Lorente, S. Schlimme, C. Sfienti, M. Thiel, T. Weber, V. I. Dormenev, A. A. Fedorov, M. V. Korzhik, O. V. Missevitch, V. Balanutsa, V. Chernetsky, A. Demekhin, A. Dolgolenko, P. Fedorets, A. Gerasimov, V. Goryachev, V. Varentsov, A. Boukharov, O. Malyshev, I. Marishev, A. Semenov, F. Böhmer, S. Dørheim, B. Ketzer, S. Paul, A. K. Hergemöller, A. Khoukaz, E. Köhler, A. Täschner, J. Wessels, R. Varma, A. Chaterjee, V. Jha, S. Kailas, B. J. Roy, Y. Yan, K. Chinorat, K. Khanchai, L. Ayut, S. Pomrad, E. Baldin, K. Kotov, S. Peleganchuk, Yu. Tikhonov, J. Boucher, V. Chambert, A. Dbeyssi, M. Gumberidze, T. Hennino, M. Imre, R. Kunne, C. Le Galliard, B. Ma, D. Marchand, A. Maroni, S. Ong, B. Ramstein, P. Rosier, E. Tomasi-Gustafsson, J. Van de Wiele, G. Boca, A. Braghieri, S. Costanza, P. Genova, L. Lavezzi, P. Montagna, A. Rotondi, V. Abramov, N. Belikov, A. Davidenko, A. Derevschikov, Y. Goncharenko, V. Grishin, V. Kachanov, D. Konstantinov, V. Kormilitsin, Y. Melnik, A. Levin, N. Minaev, V. Mochalov, D. Morozov, L. Nogach, S. Poslavskiy, A. Ryazantsev, S. Ryzhikov, P. Semenov, I. Shein, A. Uzunian, A. Vasiliev, A. Yakutin, T. Bäck, B. Cederwall, K. Makónyi, P. E. Tegnér, K. M. von Würtemberg, S. Belostotski, G. Gavrilov, A. Itzotov, A. Kashchuk, A. Kisselev, P. Kravchenko, O. Levitskaya, S. Manaenkov, O. Miklukho, Y. Naryshkin, D. Veretennikov, V. Vikhrov, A. Zhadanov, D. Alberto, A. Amoroso, M. P. Bussa, L. Busso, F. De Mori, M. Destefanis, L. Fava, L. Ferrero, M. Greco, M. Maggiora, S. Marcello, S. Sosio, S. Spataro, L. Zotti, D. Calvo, S. Coli, P. De Remigis, A. Filippi, G. Giraudo, S. Lusso, G. Mazza, O. Morra, A. Rivetti, R. Wheadon, F. Iazzi, A. Lavagno, H. Younis, R. Birsa, F. Bradamante, A. Bressan, A. Martin, H. Clement, B. Galander, L. Caldeira Balkeståhl, H. Calén, K. Fransson, T. Johansson, A. Kupsc, P. Marciniewski, E. Thomé, M. Wolke, J. Zlomanczuk, J. Díaz, A. Ortiz, K. Dmowski, P. Duda, R. Korzeniewski, B. Slowinski, A. Chlopik, Z. Guzik, K. Kosinski, D. Melnychuk, A. Wasilewski, M. Wojciechowski, S. Wronka, A. Wysocka, B. Zwieglinski, P. Bühler, O. N. Hartman, P. Kienle, J. Marton, K. Suzuki, E. Widmann, and J. Zmeskal

Subjects
Straw tube, Nuclear and High Energy Physics, Spectrometer, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Computer science, Detector, Tracking (particle physics), 01 natural sciences, Particle identification, NO, Set (abstract data type), Computer Science::Hardware Architecture, 0103 physical sciences, Trajectory, Benchmark (computing), Nuclear Experiment, 010306 general physics, Simulation
Abstract

This document describes the technical layout and the expected performance of the Straw Tube Tracker (STT), the main tracking detector of the $\bar{P}$ANDA target spectrometer. The STT encloses a Micro-Vertex-Detector (MVD) for the inner tracking and is followed in beam direction by a set of GEM stations. The tasks of the STT are the measurement of the particle momentum from the reconstructed trajectory and the measurement of the specific energy loss for a particle identification. Dedicated simulations with full analysis studies of certain proton-antiproton reactions, identified as being benchmark tests for the whole $\bar{P}$ANDA scientific program, have been performed to test the STT layout and performance. The results are presented, and the time lines to construct the STT are described.

Published
2013
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129. In uterosFlt-1 exposure differentially affects gene expression patterns in fetal liver

Author

Stojanovska, V., Holwerda, K. M., van der Graaf, A. M., Verkaik-Schakel, R. N., Boekschoten, M. V., Faas, M. M., Scherjon, S. A., and Plösch, T.

Abstract

AbstractThe soluble fms-like tyrosine kinase factor 1 (sFlt-1) is a major contributor to antiangiogenesis during preeclampsia. However, little is known about the effects of sFlt-1 on fetal health. In this study we aim to evaluate the effects of the sFlt-1 concentration during pregnancy on fetal liver physiology. We used adenoviral gene delivery in Sprague-Dawley dams (seven females, 10 weeks old) during mid-gestation (gestational day 8) with adenovirus overexpressing sFlt-1, and age-matched controls (six females, 10 weeks old) with empty adenoviral virus in order to quantify the sFlt-1 concentrations in pregnant dams. Dams exposed to adenoviral sFlt-1 delivery were subdivided into a low (n=4) and high sFlt-1 (n=3) group based on host response to the virus. One-way analysis of variance showed that fetuses (five per dam) exposed to high sFlt-1 concentrations in uteroshow fetal growth restriction (1.84±0.043 g high sFlt-1 v.2.32±0.036 g control; mean (M)±s.e.m.; P<0.001), without hypertension or proteinuria in the dams. In continuation, the microarray analysis of the fetal liver of the high sFlt-1 group showed significant enrichment of key genes for fatty acid metabolism and Ppara targets. In addition, using pyrosequencing, we found that the Ppara enrichment in the high sFlt-1 group is accompanied by decreased methylation of its promoter (1.89±0.097 mean % methylation in high sFlt-1 v.2.26±0.095 mean % methylation in control, M±s.e.m., P<0.02). Our data show that high sFlt-1 concentrations during pregnancy have detrimental effects on the fatty acid metabolism genes and the Ppara targets in the fetal liver.

Published
2019
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130. Measuring and theorizing regional governance

Author

Eaton, Kent, Faguet, Jean-Paul, Harbers, Imke, Schakel, Arjan H., Hooghe, Liesbet, Marks, Gary, Niedzwiecki, Sara, Osterkatz, Sandra Chapman, and Shair-Rosenfield, Sarah

Abstract

ABSTRACTThis symposium Regional Authority and the Postfunctionalist Theory of Governance engages two recent books on regional governance. The first sets out a measure of regional authority for 81 countries in North America, Europe, Latin America, Asia and the Pacific between 1950 and 2010. The second theorizes how regional governance is shaped by functional and communal pressures. These pressures are detected in many historical episodes of jurisdictional reform. These books seek to pin them down empirically. Community and efficiency appear to have tangible and contrasting effects that explain how jurisdictions are designed, why regional governance has become differentiated and how multilevel governance has deepened over the past several decades. The symposium consists of contributions by Kent Eaton, Jean-Paul Faguet and Imke Harbers followed by a response from the authors: Liesbet Hooghe, Gary Marks, Arjan H. Schakel, Sara Niedzwiecki, Sandra Chapman Osterkatz and Sarah Shair-Rosenfield, Measuring Regional Authority: A Postfunctionalist Theory of Governance, Vol. I. Oxford: Oxford University Press, 2016; and Liesbet Hooghe and Gary Marks, with Arjan H. Schakel, Sara Niedzwiecki, Sandra Chapman Osterkatz and Sarah Shair-Rosenfield, Community, Scale, and Regional Governance: A Postfunctionalist Theory of Governance, Vol. II. Oxford: Oxford University Press, 2016.

Published
2019
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131. Trigger-less readout of the PANDA electromagnetic calorimeter

Author

P. Drexler, G. Tambave, T. Nishizawa, Till Kuske, P.J.J. Lemmens, D. Bremer, T. Eissner, P. Schakel, M. Kavatsyuk, M. Hevinga, F. Schreuder, H. Moeini, R. Speelman, and Herbert Löhner

Subjects
Physics, Signal processing, Physics::Instrumentation and Detectors, business.industry, Pulse generator, Optical link, Detector, Analog-to-digital converter, law.invention, Data acquisition, law, Nuclear electronics, Electronic engineering, business, Field-programmable gate array, Computer hardware
Abstract

The PANDA collaboration at the future FAIR facility at Darmstadt, Germany, will employ antiproton annihilations to investigate resonances in the charmonium mass region. In order to gain high flexibility for physics event selection, a readout system without hardware trigger, i.e. a trigger-less data-acquisition system will be employed and is currently being developed. The event-selection is based on high-level reconstructed information, e.g. invariant mass, secondary vertices, and time correlations, which may be contributed from all sub-detector systems. Prototypes of the PANDA Electromagnetic Calorimeter have been exploited to verify the desired event-selection approach. The prototype readout system includes a dedicated Sampling ADC (SADC), data concentrator (DCON) and compute-node (CN) modules. An optical link connects several SADC digitizers to a DCON module from where the data are streamed to the CN network. Data, collected by the SADCs are processed online in FPGAs by a feature-extraction algorithm. This processing technique guarantees a dead-time free operation and allows including an on-line pile-up recovery process for single detector counting rates up to 1 MHz. The prototype of the readout-chain has been evaluated using pulse generators and high-energy photon beams; the proper event correlation could be verified. The applied FPGA has been irradiated with protons to demonstrate its applicability in the radiation environment of the PANDA experiment.

Published
2012
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132. Trigger-less readout electronics for the PANDA Electromagnetic Calorimeter

Author

P. Schakel, I. Konorov, Herbert Löhner, M. Kavatsyuk, G. Tambave, Pawel Marciniewski, F. Schreuder, P.J.J. Lemmens, Tord Johansson, R. Speelman, M. Hevinga, KVI - Center for Advanced Radiation Technology, and Research unit Nuclear & Hadron Physics

Subjects
Physics, business.industry, Clock signal, Physics::Instrumentation and Detectors, Electromagnetic compatibility, Electrical engineering, Readout electronics, Event selection, Electromagnetic calorimeter, Data acquisition, Nuclear electronics, Invariant mass, business, Computer hardware
Abstract

The PANDA experiment at the future FAIR facility at Darmstadt, Germany, will employ a novel electronics-readout concept: the trigger-less readout. This concept implies an event selection based on the physics properties of detected particles, such as reconstructed invariant mass or a detected secondary vertex. Such an approach requires a completely new design of the readout chain from the front-end to the data acquisition. This paper describes a fully-functional prototype of the readout chain for one of the PANDA subdetectors - the Electromagnetic Calorimeter. The prototype consists of digitizer and data-multiplexer modules. The crucial component of the prototype is the synchronous optical-link connection, which allows to transfer clock signal and time-synchronisation commands in an unambiguous way. The implementation and performance tests of the synchronous optical-link connection are described in the paper.

Published
2011

133. Time-Resolved Polarization of Luminescence Spectroscopy: An Accurate and Versatile Digital Instrument for the Sub-μs Time Domain

Author

P. Schakel, Harry P.J.M. Dekkers, R. B. Rexwinkel, and S. C. J. Meskers

Subjects
Spectrometer, Photoelastic modulator, business.industry, Chemistry, 010401 analytical chemistry, Optical polarization, 01 natural sciences, 0104 chemical sciences, 010309 optics, Optics, Duty cycle, 0103 physical sciences, Time domain, Time-resolved spectroscopy, Luminescence, business, Instrumentation, Spectroscopy, Circular polarization
Abstract

An instrument is described for the measurement of circular and linear polarizations of the luminescence with a time resolution up to 50 ns. The spectrometer, which makes use of a 50-kHz photoelastic modulator and a differential photon-counting technique, is accurate and absolute and is capable of detecting small degrees of polarization. Making use of excitation light pulses which lie randomly in the modulator's duty cycle, the instrument can be readily interfaced with a variety of externally triggered or free running pulsed light sources.

Published
1993
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134. Time-resolved and continuous-wave circular polarisation of luminescence spectroscopy using a commercial spectrofluorimeter

Author

H P J M Dekkers, P M L Blok, and P Schakel

Subjects
Materials science, Spectrometer, business.industry, Applied Mathematics, Mass spectrometry, Particle detector, Optics, Continuous wave, Time domain, Luminescence, business, Spectroscopy, Instrumentation, Engineering (miscellaneous)
Abstract

An instrument is described for time-resolved (TR) detection of circular polarisation of the luminescence (CPL). The TR-CPL spectrometer combines the optical part of a commercially available gated photon-counting spectrofluorimeter with the differential photon-counting system of a home-built continuous-wave (CW) CPL instrument described previously. The resulting spectrometer is sensitive and accurate, and allows for the determination of circular (and linear) polarisation data in the time domain 10 mu s-100 ms. Similarly, a CW photon-counting spectrofluorimeter can be transformed into a high performance CPL spectrometer.

Published
1990
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135. New indicator for comparing the energy performance of CO2 utilization concepts.

Author

Schakel, Wouter, Fernández-Dacosta, Cora, van der Spek, Mijndert, and Ramírez, Andrea

Subjects
CARBON dioxide, GREENHOUSE gases, ENERGY consumption
Abstract

CO 2 utilization is increasingly considered a greenhouse gas abatement strategy alternatively to CO 2 storage. Existing indicators that assess the performance of CO 2 utilization options often provide an incomplete perspective and are unsuitable to compare different utilization options with different functionality (e.g. plastics and fuels). This study introduces a new performance indicator for CO 2 utilization options: Specific Primary Energy Consumption per unit of Fossil feedstock Replaced (SPECFER). This indicator, expressed in MJ/MJ, provides a proxy for the energy efficiency of which CO 2 conversion options can replace fossil feedstock required in conventional processes. Three CO 2 utilization case studies (CO 2 based methanol, polyols and dimethyl ether) are used to show the application and effectiveness of the SPECFER indicator. Among the case studies, only CO 2 conversion into polyol appears particularly efficient (SPECFER of 0.05 MJ/MJ), while the other options are not (SPECFER of > 1 MJ/MJ). The paper shows that the SPECFER indicator adds key insights compared to conventional indicators to the effectiveness of CO 2 utilization options and is a promising indicator complementary to CO 2 emissions reduction or life cycle greenhouse gas reduction potential. The SPECFER thus improves the understanding of the performance of CO 2 utilization and enables the possibility to distinctly compare different CO 2 converting utilization technologies. [ABSTRACT FROM AUTHOR]

Published
2017
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136. Impact of Fuel Selection on Techno-environmental Performance of Post-combustion Calcium Looping Process Applied to a Cement Plant.

Author

Schakel, Wouter, Orregioni, Gabriel, Strømman, Anders, and Ramirez, Andrea

Abstract

Calcium looping CO 2 capture is a promising technology to reduce CO 2 emissions from cement production. Coal is generally considered the fuel used to drive the calcium looping process as coal is already used as feedstock for cement production. This study assesses the impact of different fuels (coal, natural gas and woody biomass) on the technological and environmental performance of post-combustion calcium looping at a cement plant in North-western Europe. Process modelling is used to determine the impact of the different fuels on the mass and energy balance of the process. Life cycle assessment is carried out to evaluate the environmental performance of the different systems. Results indicate that firing natural gas or biomass instead of coal in an add-on calcium looping process can improve the efficiency of the process, as it decreases the fuel, limestone and electricity consumption. Consequently, while coal fired calcium looping can reduce life cycle climate change potential by 92%, the use of natural gas or biomass can make the process carbon neutral (reduction of 100%) or negative (-169%), respectively. Further research is required to complete the environmental perspective of using alternative fuels, but these results already illustrate a potential low-hanging fruit to improve the environmental performance of post combustion calcium looping in the cement industry. [ABSTRACT FROM AUTHOR]

Published
2017
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137. Feasibility Assessment of CO2 Capture Retrofitted to an Existing Cement Plant: Post-combustion vs. Oxy-fuel Combustion Technology.

Author

Gerbelová, Hana, van der Spek, Mijndert, and Schakel, Wouter

Abstract

This research presents a preliminary techno-economic evaluation of CO 2 capture integrated with a cement plant. Two capture technologies are evaluated, monoethanolamine (MEA) post-combustion CO 2 capture and oxy-fuel combustion. Both are considered potential technologies that could contribute to reduction of CO 2 emissions in the cement industry. The study compares these two technologies in terms of technical performance, investment costs, and operational costs. The case study is applied to the one of the largest cement plants in Portugal, Alhandra. The results show that the amount of CO 2 avoided using the post-combustion MEA technology is lower due to additional emissions from reboiler steam production. Moreover, the total capital investment of the post-combustion CO 2 capture system is estimated at 260 M€ 2014 and the annual operation and maintenance costs of around 43 M€ 2014 ; whereas the oxy-fuel combustion CO 2 capture requires a capital investment of about 217 M€ 2014 and 37 M€ 2014 annually for operation and maintenance. This indicates that the oxy-fuel CO 2 capture technology may be a better choice in terms of costs. However, this technology implies higher technical uncertainties concerning integration with the cement plant. [ABSTRACT FROM AUTHOR]

Published
2017
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138. Scanning probe microscopes go video rate and beyond

Author

C. F. Overgauw, B. Okhuijsen, Joost W. M. Frenken, M. Seynen, L. Crama, A. Vijftigschild, Koen Schoots, G. B. E. M. van Velzen-Williams, W. van Loo, H. ter Horst, R. Schumm, Patrick Han, E. van Tol, Allard J. Katan, H. Dekker, Tjerk H. Oosterkamp, P. Schakel, M. J. Rost, and Surfaces and Thin Films

Subjects
Materials science, Microscope, Preamplifier, business.industry, Bandwidth (signal processing), Image processing, Frame rate, law.invention, Scanning probe microscopy, Optics, law, Scanning tunneling microscope, business, Instrumentation, Image resolution
Abstract

In this article we introduce a, video-rate, control system that can be used with any type of scanning probe microscope, and that allows frame rates up to 200images∕s. These electronics are capable of measuring in a fast, completely analog mode as well as in the more conventional digital mode. The latter allows measurements at low speeds and options, such as, e.g., atom manipulation, current–voltage spectroscopy, or force–distance curves. For scanning tunneling microscope (STM) application we implemented a hybrid mode between the well-known constant-height and constant-current modes. This hybrid mode not only increases the maximum speed at which the surface can be imaged, but also improves the resolution at lower speeds. Acceptable image quality at high speeds could only be obtained by pushing the performance of each individual part of the electronics to its limit: we developed a preamplifier with a bandwidth of 600kHz, a feedback electronics with a bandwidth of 1MHz, a home-built bus structure for the fas...

Published
2005

139. Ideological congruence and socio-economic inequality

Author

Schakel, Wouter and Hakhverdian, Armen

Abstract

This study examines whether or not political representation in the Netherlands is biased toward the rich and higher educated by comparing the political orientations of members of parliament to those of the electorate. The analyses reveal stark differences in the representation of different socio-economic groups. The political views of elected national representatives are far more similar to those of rich, higher educated citizens than to those with less income and education. Moreover, a longitudinal analysis reveals that inequalities in political representation have actually grown in recent years. We also show that the use of measures of ideological self-identification might to lead to highly misleading results regarding the nature of political representation as opposed to the use of issue items. We conclude that, despite a highly proportional electoral system, the views which are represented in the Dutch lower house of parliament contain major distortions of the views of the broader electorate.

Published
2018
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140. The fetal programming effect of prenatal smoking on Igf1r and Igf1 methylation is organ- and sex-specific

Author

Meyer, Karolin F., Verkaik-Schakel, Rikst Nynke, Timens, Wim, Kobzik, Lester, Plösch, Torsten, and Hylkema, Machteld N.

Subjects
DNA methylation, epigenetics, liver, lung, mouse, prenatal, pyrosequencing
Abstract

The impact of prenatal smoke exposure (PSE) on DNA methylation has been demonstrated in blood samples from children of smoking mothers, but evidence for sex-dependent smoke-induced effects is limited. As the identified differentially methylated genes can be associated with developmental processes, and insulin-like growth factors (IGFs) play a critical role in prenatal tissue growth, we hypothesized that PSE induces fetal programming of Igf1r and Igf1. Using a mouse model of smoking during pregnancy, we show that PSE alters promoter methylation of Igf1r and Igf1 and deregulates their gene expression in lung and liver of fetal (E17.5) and neonatal (D3) mouse offspring. By further comparing female versus male, lung versus liver, or fetal versus neonatal time point, our results demonstrate that CpG site-specific aberrant methylation patterns sex-dependently vary per organ and time point. Moreover, PSE reduces gene expression of Igf1r and Igf1, dependent on organ, sex, and offspring's age. Our results indicate that PSE may be a source of organ-specific rather than general systemic fetal programming. This is exemplified here by gene promoter methylation and mRNA levels of Igf1r and Igf1, together with a sex- and organ-specific naturally established correlation of both parameters that is affected by prenatal smoke exposure. Moreover, the comparison of fetuses with neonates suggests a CpG site-dependent reversibility/persistence of PSE-induced differential methylation patterns.

Published
2018
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141. Assessing the techno-environmental performance of CO2 utilization via dry reforming of methane for the production of dimethyl ether.

Author

Schakel, Wouter, Ramírez, Andrea, Oreggioni, Gabriel, Singh, Bhawna, and Strømman, Anders

Subjects
CARBON dioxide, METHANE, METHYL ether
Abstract

CO 2 utilization is gaining attention as a greenhouse gas abatement strategy complementary to CO 2 storage. This study explores the techno-environmental performance of CO 2 utilization trough dry reforming of methane into syngas for the production of dimethyl ether (DME). The CO 2 source is a hydrogen production unit at a refinery, where solvent based CO 2 capture is applied. Aspen+ modelling and hybrid life cycle assessment (LCA) is used to assess the techno-environmental performance of this utilization option compared to a reference case without CO 2 capture and a case with CO 2 capture and storage. Results of the technical assessment show that although 94% of the captured CO 2 can be utilised for DME production, only 9% of CO 2 is avoided in the entire process as a result of direct CO 2 formation during DME synthesis and the combustion of syngas to provide the heat demanded by the dry reforming process. Besides, a substantial amount of electricity is required for syngas compression. Consequently, the LCA results indicate that climate change potential (CCP) is reduced by 8% while it is 37% higher than CCP when CO 2 is stored and DME is produced conventionally. Sensitivity analyses are performed on various process conditions. Overall, this study indicates that this utilization route lowers the CCP although the reduction is limited compared to CCS. While the techno-environmental analysis is a useful tool to gain better insights in the performance of CO 2 utilization options, the complex environmental trade-offs make it difficult to draw robust conclusions on the performance. [ABSTRACT FROM AUTHOR]

Published
2016
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143. New indicator for comparing the energy performance of CO2utilization concepts

Author

Schakel, Wouter, Fernández-Dacosta, Cora, van der Spek, Mijndert, and Ramírez, Andrea

Abstract

•A new performance indicator for CO2utilization is introduced.•Indicator is a proxy for the energy efficiency of CO2utilization options.•Three example case studies highlight the applicability of the indicator.•Indicator enables comparison of CO2utilization options with different functionality.

Published
2017
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144. The fetal programming effect of prenatal smoking on Igf1rand Igf1methylation is organ- and sex-specific

Author

Meyer, Karolin F., Verkaik-Schakel, Rikst Nynke, Timens, Wim, Kobzik, Lester, Plösch, Torsten, and Hylkema, Machteld N.

Abstract

ABSTRACTThe impact of prenatal smoke exposure (PSE) on DNA methylation has been demonstrated in blood samples from children of smoking mothers, but evidence for sex-dependent smoke-induced effects is limited. As the identified differentially methylated genes can be associated with developmental processes, and insulin-like growth factors (IGFs) play a critical role in prenatal tissue growth, we hypothesized that PSE induces fetal programming of Igf1rand Igf1.Using a mouse model of smoking during pregnancy, we show that PSE alters promoter methylation of Igf1rand Igf1and deregulates their gene expression in lung and liver of fetal (E17.5) and neonatal (D3) mouse offspring. By further comparing female versus male, lung versus liver, or fetal versus neonatal time point, our results demonstrate that CpG site-specific aberrant methylation patterns sex-dependently vary per organ and time point. Moreover, PSE reduces gene expression of Igf1rand Igf1, dependent on organ, sex, and offspring's age. Our results indicate that PSE may be a source of organ-specific rather than general systemic fetal programming. This is exemplified here by gene promoter methylation and mRNA levels of Igf1rand Igf1,together with a sex- and organ-specific naturally established correlation of both parameters that is affected by prenatal smoke exposure. Moreover, the comparison of fetuses with neonates suggests a CpG site-dependent reversibility/persistence of PSE-induced differential methylation patterns.

Published
2017
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145. Serum Concentration of Anti-TNF Antibodies, Adverse Effects and Quality of Life in Patients with Inflammatory Bowel Disease in Remission on Maintenance Treatment.

Author

Brandse, Johannan F., Vos, Laura M. C., Jansen, Jeroen, Schakel, Toos, Ponsioen, Cyriel I. J., van den Brink, Gijs R., D'Haens, Geert R., and Löwenberg, Mark

Abstract

Background and aims: High serum concentrations of infliximab [IFX] and adalimumab [ADA] may be associated with adverse effects in patients with inflammatory bowel disease [IBD]. We aimed to investigate whether high anti-tumour necrosis factor [TNF] trough levels [TLs] were associated with toxicity and impaired quality of life [QoL]. Methods: We conducted a prospective cohort study in IBD patients in clinical and biochemical remission on IFX or ADA maintenance therapy. Trough serum concentrations and antidrug antibodies were measured in addition to biochemical markers of inflammation in serum and stool to confirm quiescent disease. QoL was assessed using the Inflammatory Bowel Disease Questionnaire and 36-item short form]. Side effects such as fatigue and arthralgia were measured with a visual analogue score [VAS]. Skin toxicity was reported with a European Organization for Research and Treatment of Cancer-derived score. Results: In all, 252 IBD patients on maintenance anti-TNF therapy were screened, of whom 95 [73 with Crohn's disease, 22 with ulcerative colitis; 72 on IFX, 23 on ADA] were in clinical and biochemical remission and were included. Median TLs were 5.5 µg/ml and 6.6 µg/ml for IFX and ADA, respectively. Patients with anti-TNF TLs above median had lower IBDQ scores than patients with lower TLs [IBDQ 176 vs 187, p = 0.02], particularly regarding systemic symptoms and emotional status. A trend towards lower SF-36 and higher fatigue scores was observed in the higher anti-TNF TL group. Skin and arthralgia scores were not significantly different between the groups. Conclusions: IBD patients with higher anti-TNF serum concentrations had significantly lower disease-specific QoL. Fatigue, arthralgia, and skin lesions do not occur more often in these patients. These data are reassuring that high serum concentrations of anti-TNF antibodies are not toxic. [ABSTRACT FROM AUTHOR]

Published
2015
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146. Exploring the potential impact of implementing carbon capture technologies in fossil fuel power plants on regional European water stress index levels.

Author

Schakel, Wouter, Pfister, Stephan, and Ramírez, Andrea

Subjects
FOSSIL fuel power plants, CARBON sequestration, WATER chemistry, COOLING
Abstract

Equipping power plants with carbon capture technology can affect cooling demand and water use. This study has explored the potential impact of large scale deployment of power plants with carbon capture technologies on future regional water stress in Europe. A database including 458 of European largest power plants with data on location, technology, age, fuel type, amount of electricity generation and cooling method has been developed. This data has been combined with literature data on water use rates and developed scenarios to calculate corresponding water use of these European power plants for 2030 and 2050 under different conditions, such as the penetration level of carbon capture technologies and installed technologies. Water stress methodology based on water withdrawal has been used to explore the impact of carbon capture and storage on future water stress levels. Our findings indicate that by 2030, no considerable increase in water stress is expected due to the instalment of carbon capture technologies. However, when assuming a high penetration level of carbon capture technologies, water stress in 2050 might substantially increase in many regions in Europe. The extent of the increase in water stress strongly depends on penetration level of carbon capture, installed power plant and cooling technologies and applied water stress methodology. When using water consumption to estimate water stress, the results do not indicate significant changes in water stress for the scenarios with carbon capture. Nevertheless, as water stress based on water withdrawal is currently the common method, the results of this study provide reasons for concern regarding the potential impact of carbon capture on future European water stress levels and indicate the need for future research to monitor and possibly prevent potential water stress increases from the instalment of carbon capture technologies. [ABSTRACT FROM AUTHOR]

Published
2015
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147. Getting the Human Factor into Traffic Flow Models

Author

van Lint, Hans, Schakel, Wouter, Tamminga, Guus, Knoppers, Peter, and Verbraeck, Alexander

Abstract

Automated driving may lead to much higher road capacities, combined with increased road safety, increased driver comfort, and lower costs. Although this vision may hold ground in the long run, first a transitional period will take place in which increasing percentages of vehicles with many levels of automation will drive on the world’s road networks. This transition poses a fundamental scientific challenge. The models used today to simulate and predict vehicular traffic are not valid to predict emergent properties of traffic flows under increasing amounts of vehicle automation. For example, there is no idea of how drivers of nonautomated vehicles will respond to other drivers reading their morning papers behind the steering wheel or the consequences of such interactions on traffic safety and capacity. In this paper, the authors do not propose a new behavioral theory with which the effects of increasing vehicle automation can be predicted. What the authors propose is an advanced open-source simulation framework, OpenTrafficSim, which makes it possible to extend microscopic models incrementally with explanatory mental models, such that new behavioral theories can be tested and shared within the community. Given the societal importance of predicting the effects on safety and efficiency of vehicle automation, the authors sincerely hope this paper will fuel the discussion on how both open-source and closed-source simulation software can be adapted and made ready for the next generation of traffic simulation models that are needed in the coming decades.

Published
2016
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148. Assessing the techno-environmental performance of CO2utilization via dry reforming of methane for the production of dimethyl ether

Author

Schakel, Wouter, Oreggioni, Gabriel, Singh, Bhawna, Strømman, Anders, and Ramírez, Andrea

Abstract

•Utilizing CO2into dimethyl ether improves techno-environmental performance.•Climate change potential reduction is limited compared to CO2capture and storage.•Environmental trade-offs of CCU more complex than those of CO2capture and storage.•Techno-environmental analysis improves insights in performance of CO2utilization options.

Published
2016
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149. Assessment of Implementing Carbon Capture Technologies in Fossil Fuel Power Plants on Regional European Water Stress Index Levels.

Author

Schakel, Wouter, Pfister, Stephan, and Ramírez, Andrea

Abstract

Equipping power plants with carbon capture technologies increases the (cooling) water demand of these plants. This study explores the potential impact of such increase in water demand on the regional water scarcity in Europe. A database with key characteristics of 458 of the largest European power plants is developed and the water use of these power plants is estimated. The water use of the power plants are spatially linked to current water stress index levels. Several prospective scenarios are developed accounting for variations in the future configuration of Europe's electricity generation and different penetration rates of carbon capture technology. Regional water stress index levels are calculated to compare the potential impact of applying carbon capture technologies on the water stress. Preliminary results indicate that the increase of water use due to carbon capture technology is partly expected to be compensated by the deployment of more efficient energy conversion methods which require less cooling water. As such, no significant increase in water stress is expected in the short term (2030), as the carbon capture penetration level in European power plants is expected to be quite low. However, on the long term (2050), large scale instalment of carbon capture technologies in power plants might significantly increase the water stress throughout Europe. [ABSTRACT FROM AUTHOR]

Published
2014
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150. Environmental Due Diligence of CO2 Capture and Utilization Technologies – Framework and application.

Author

Singh, Bhawna, Reijers, Rick, van der Spek, Mijndert W., Schakel, Wouter B., Skagestad, Ragnhild, Haugen, Hans Aksel, Ramirez, Andrea, Eldrup, Nils Henrik, Hertwich, Edgar G., and Strømman, Anders Hammer

Abstract

This article presents an overview of an environmental due diligence framework developed as part of the EDDiCCUT project, and presents analysis and results from the first test case – MEA based CO 2 capture process. The framework draws upon well-established technical, economic and environmental assessment methods and integrates technical performance, uncertainties, cost estimation and life cycle inventory data to ensure consistency and enhance quality. Results show that for the modelled coal power plant of about 800 MW gross power output, the CO 2 capture system lowers the net efficiency by 10.4% efficiency points and results in a 68% increase in the cost of electricity. Environmental performance evaluated on a broad range of 24 impacts and emission categories indicates a 68% reduction in climate change warming potential with 20-90% increase in other impacts. By comparing the quality of the inventory data used for environmental assessment with the state-of-art data in available life cycle assessment literature, it is found that the due diligence analysis brings significant improvement in the quality of data for certain processes in the value chain. [ABSTRACT FROM AUTHOR]

Published
2014
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