446 results on '"PULMONARY valve diseases"'
Search Results
102. A Mysterious Case of Spontaneous Cervical Epidural Hematoma and Bilateral Primary Spontaneous Pneumothorax Caused by a Rare Etiology.
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Thakkar, Keta, Ajayan, Neeraja, Unnikrishnan, P., Sethuraman, Manikandan, and Hrishi, Ajay P.
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CEREBROVASCULAR disease , *CERVICAL vertebrae , *PULMONARY emphysema , *EPIDURAL hematoma , *LENGTH of stay in hospitals , *PNEUMOTHORAX , *DISEASE relapse , *PLEURODESIS , *DISEASE complications ,PULMONARY valve diseases - Abstract
Spontaneous spinal epidural hematoma (SSEH) is a rare disorder that can present as an acute onset of pain and radicular symptoms that mimic disc herniation. Primary spontaneous pneumothorax (PSP) can be defined as the presence of air in the pleural space without apparent underlying lung disease or trauma. We describe a rare case of SSEH in the cervical spine (C5-7) presenting with a novel association, a bilateral PSP, which has never been documented before. Both SSEH and spontaneous pneumothorax, though rare, can be associated with vasculopathy and our patient had signs of vasculopathy of intracranial vessels and pulmonary vasculature. Vasculopathy also needs to be considered while evaluating a case of PSP without emphysema-like changes (ELC) and if diagnosed as the cause, pleurodesis could be considered as a part of the management to avoid the sequel of recurrent pneumothorax and prolonged ICU stay in this subset of patients. [ABSTRACT FROM AUTHOR]
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- 2019
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103. Pulmoner Kapak Yokluğu Sendromu ile Beraber Olan Fallot Teralojisi'nde Nadir Görülen Kardiyak Anomali.
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Akgün, Gökmen, Ergin, Selma Oktay, Yılmaz, Emine Hekim, Öner, Taliha, and Çelebi, Ahmet
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CARDIOVASCULAR system abnormalities , *CONGENITAL heart disease , *PATENT ductus arteriosus , *PULMONARY artery , *TETRALOGY of Fallot , *PULMONARY valve , *DISEASE complications , *DISEASE risk factors ,PULMONARY valve diseases - Abstract
Heart failure and cardiomegaly are observed in patients with absent pulmonary valve syndrome with tetralogy of Fallot (TOF), unlike in those with TOF alone. Additional cardiac anomalies can also be seen in these patients, although not frequently. In our case, we found that the right and left pulmonary arteries were disconnected (the main pulmonary artery continued only with the right pulmonary artery and the left pulmonary artery originating from patent ductus arteriosus). In this paper, we wanted to remember other cardiac anomalies associated with absent pulmonary valve syndrome with tetralogy of Fallot. [ABSTRACT FROM AUTHOR]
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- 2018
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104. Reports Summarize Pulmonary Atresia Study Results from Dublin (Echocardiographic Parameters for Risk Prediction in Borderline Right Ventricle: Review with Special Emphasis on Pulmonary Atresia with Intact Ventricular Septum and Critical...).
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HEART septum ,PULMONARY atresia ,HEART valve diseases ,ECHOCARDIOGRAPHY ,PULMONARY valve diseases - Abstract
Keywords: Angiology; Cardiology; Cardiovascular; Cardiovascular Abnormalities; Congenital Abnormalities; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Septum; Heart Valve Diseases and Conditions; Pulmonary Atresia; Risk and Prevention; Stenosis; Vascular Malformations; Ventricular Septum EN Angiology Cardiology Cardiovascular Cardiovascular Abnormalities Congenital Abnormalities Health and Medicine Heart Disease Heart Disorders and Diseases Heart Septum Heart Valve Diseases and Conditions Pulmonary Atresia Risk and Prevention Stenosis Vascular Malformations Ventricular Septum 595 595 1 07/31/23 20230731 NES 230731 2023 JUL 31 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- Investigators discuss new findings in pulmonary atresia. Angiology, Cardiology, Cardiovascular, Cardiovascular Abnormalities, Congenital Abnormalities, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Septum, Heart Valve Diseases and Conditions, Risk and Prevention, Stenosis, Vascular Malformations, Pulmonary Atresia, Ventricular Septum. [Extracted from the article]
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- 2023
105. A Prospective Multicenter Pivotal Study to Evaluate Safety and Effectiveness of Venus-Neo Surgical Aortic Valve.
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AORTIC valve ,HEART valve prosthesis implantation ,HEART diseases ,PULMONARY valve diseases ,HEART valve diseases ,BIOPROSTHETIC heart valves - Abstract
Angiology, Aortic Valve, Bioengineering, Biomedical, Biomedical Engineering, Biomedical Engineering - Bioprosthetics, Biomedicine, Bioprosthetics, Cardio Device, Cardiology, Cardiovascular, Cardiovascular Diseases and Conditions, Cardiovascular Research, Clinical Research, Clinical Trials and Studies, Drugs and Therapies, Embolism and Thrombosis, Endocarditis, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valves, Hematology, Hemorrhage, Medical Devices, Thrombosis, Vascular Diseases and Conditions. [Extracted from the article]
- Published
- 2023
106. Dexamethasone/prednisolone: Lack of efficacy: 9 case reports.
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DEXAMETHASONE , *PREDNISOLONE , *SENSORINEURAL hearing loss ,PULMONARY valve diseases - Published
- 2023
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107. Central China Fuwai Hospital of Zhengzhou University Researcher Has Provided New Study Findings on Pulmonary Atresia (Novel rare genetic variants of familial and sporadic pulmonary atresia identified by whole-exome sequencing).
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PULMONARY atresia ,GENETIC variation ,UNIVERSITY hospitals ,HEART valve diseases ,PULMONARY valve diseases ,CONGENITAL heart disease - Abstract
Cardiology, Cardiovascular, Congenital Abnormalities, Genetics, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Pulmonary Atresia, Cardiovascular Abnormalities, Vascular Malformations Keywords: Cardiology; Cardiovascular; Cardiovascular Abnormalities; Congenital Abnormalities; Genetics; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Valve Diseases and Conditions; Pulmonary Atresia; Vascular Malformations EN Cardiology Cardiovascular Cardiovascular Abnormalities Congenital Abnormalities Genetics Health and Medicine Heart Disease Heart Disorders and Diseases Heart Valve Diseases and Conditions Pulmonary Atresia Vascular Malformations 104 104 1 06/05/23 20230605 NES 230605 2023 JUN 5 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- Investigators publish new report on pulmonary atresia. [Extracted from the article]
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- 2023
108. Research from Central South University Yields New Data on Cardiovascular Medicine (Case report: Surgical valvular pulmonary reconstruction for a previous unreported rheumatic right-sided valve disease with severe pulmonary regurgitation).
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PULMONARY valve diseases ,RHEUMATIC heart disease ,SURGERY - Abstract
Keywords: Cardiovascular Medicine; Health and Medicine EN Cardiovascular Medicine Health and Medicine 679 679 1 05/29/23 20230530 NES 230530 2023 MAY 29 (NewsRx) -- By a News Reporter-Staff News Editor at Cardiovascular Week -- Researchers detail new data in cardiovascular medicine. Keywords for this news article include: Central South University, Changsha, People's Republic of China, Asia, Health and Medicine, Cardiovascular Medicine. [Extracted from the article]
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- 2023
109. Approach to residual pulmonary valve dysfunction in adults with repaired tetralogy of Fallot.
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Kim, Yuli Y. and Ruckdeschel, Emily
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PULMONARY valve diseases ,TETRALOGY of Fallot ,VENTRICULAR outflow obstruction ,HEART failure ,ARRHYTHMIA ,THERAPEUTICS ,CARDIAC catheterization ,CHRONIC diseases ,RIGHT heart ventricle ,CARDIAC surgery ,HEART valve diseases ,PROSTHETIC heart valves ,MEDICAL care ,PATIENTS ,RISK assessment ,TIME ,PULMONARY valve ,TREATMENT effectiveness ,SEVERITY of illness index ,PATIENT selection ,EXERCISE tolerance ,SURGERY ,EQUIPMENT & supplies ,PHYSIOLOGY - Abstract
Residual right ventricular outflow tract and pulmonary valve disease is common in adults with repaired tetralogy of Fallot. Chronic severe pulmonary regurgitation as a result of surgical repair can lead to myriad complications including right ventricular dysfunction, decreased exercise tolerance, right heart failure and symptomatic arrhythmias. The aim of restoring pulmonary valve integrity is to preserve right ventricular size and function with the intent of mitigating the development of symptoms and poor long-term outcomes. Right ventricular size thresholds by cardiac MRI have emerged beyond which reverse right ventricular remodelling after pulmonary valve replacement is less likely. Though pulmonary valve replacement has been shown to improve right ventricular dimensions and symptoms, no consistent improvement in right ventricular ejection fraction or objective measures of exercise capacity have been demonstrated. Furthermore, there are no long-term studies showing that normalisation of right ventricular size results in improved clinical outcomes. New transcatheter techniques of percutaneous pulmonary valve replacement have emerged with good short-term and mid-term outcomes, further adding to the complexity in determining 'when' and 'how' right ventricular outflow tract and pulmonary valve intervention should occur. With improved survival of these patients, the trend towards earlier pulmonary valve replacement at smaller right ventricular size and rapidly evolving transcatheter pulmonary valve techniques, the clinician must balance the goals of preserving right ventricular size and function in an attempt to prevent untoward outcomes with risks of multiple interventions in a patient's lifetime. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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110. Outcomes of redo pulmonary valve replacement for bioprosthetic pulmonary valve failure in 61 patients with congenital heart disease.
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Cheul Lee, Chang-Ha Lee, and Jae Gun Kwak
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PULMONARY valve , *HEART valve prosthesis implantation , *BIOPROSTHESIS , *TREATMENT effectiveness , *SURGERY , *THERAPEUTICS ,PULMONARY valve diseases - Abstract
OBJECTIVES: Although all bioprostheses used for pulmonary valve (PV) replacement (PVR) are prone to failure and will require redo PVR, data pertaining to the outcomes of this procedure are lacking. The objective of this study was to evaluate outcomes of redo PVR for bioprosthetic PV failure in patients with congenital heart disease. METHODS: A retrospective review of 61 patients who underwent redo PVR for bioprosthetic PV failure between November 1999 and June 2013 was performed. Univariable analyses were used to identify the factors associated with postoperative adverse events (PAEs). RESULTS: The median age at initial PVR was 7.0 years (1.6-36.5 years) and the median age at redo PVR was 13.5 years (7.6-43.3 years). Fundamental diagnoses were tetralogy of Fallot (n = 20), pulmonary atresia with ventricular septal defect (n = 20), double outlet right ventricle (n = 7) and others (n = 14). The median valve size was 25 mm (18-28 mm). There were 2 hospital deaths (3.3%). Eighteen patients (29.5%) experienced PAEs. PAEs were associated with higher preoperative right ventricular systolic pressure (105 ± 22 vs 89 ± 19 mmHg, P = 0.016) and longer cardiopulmonary bypass time (219 ± 77 vs 164 ± 59 min, P = 0.007). Completeness of follow-up was 98.3% and the median duration of follow-up was 5.5 years (0.1-14.3 years). There were 3 late deaths. The actuarial survival rate at 10 years was 83.7 ± 8.0%. Eleven patients underwent the second redo PVR during follow-up. The rate of freedom from the second redo PVR at 10 years was 58.8 ± 11.9%. The rate of freedom from both PV reintervention and structural valve deterioration (SVD) at 10 years was 32.0 ± 13.3%. CONCLUSIONS: A substantial number of the patients experienced mortality or morbidities after redo PVR. Higher preoperative right ventricular systolic pressure and longer cardiopulmonary bypass time were associated with PAEs. By 10 years after the redo PVR, approximately two-thirds of patients will require PV reintervention or manifest SVD. [ABSTRACT FROM AUTHOR]
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- 2016
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111. A case of a quadricuspid pulmonary valve in a Japanese female.
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Harada, Tomonori, Tsuboi, Isao, Hara, Hiroyuki, Naito, Michiko, Shimada, Kazuyuki, and Aizawa, Shin
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PULMONARY valve , *AUTOPSY , *MYOCARDIAL infarction , *JAPANESE people , *PATIENTS , *ANATOMY , *HEALTH ,PULMONARY valve diseases - Abstract
A supernumerary cusp of the pulmonary valve was incidentally found in an 88-year-old Japanese female during a gross anatomy course. The valve was composed of three equal-sized leaflets and one smaller leaflet. The supernumerary leaflet was located between the anterior and right semilunar leaflets. This pulmonary valve consisted of four pulmonary aortic bulbs. The donated body was a female who had a past history of myocardial infarction and was diagnosed as having ischemic heart disease at the last admission. Tricuspid valve regurgitation and pulmonary hypertension were diagnosed on echocardiography. These findings were considered to have been caused by left heart failure and not by the quadricuspid pulmonary valve. This asymptomatic anatomical variation might have developed from a protrusion between the anterior and right swelling of the outflow tract during semilunar valve development. [ABSTRACT FROM AUTHOR]
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- 2016
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112. Novel transoesophageal echocardiographic views attain superior incident angles for tricuspid, but not pulmonary, valvular Doppler interrogation.
- Author
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Tan, C. O., Hu, R. T. C., Harley, I., and Weinberg, L.
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TRICUSPID valve diseases , *THORACIC aorta , *ECHOCARDIOGRAPHY , *CARDIAC surgery , *DISEASES ,PULMONARY valve diseases - Abstract
For accurate spectral Doppler valvular evaluation, intraoperative sonographers must use transoesophageal echocardiographic (TOE) views that offer optimal incident angles. We hypothesised that views added to the 2013 American Society of Echocardiography/Society of Cardiovascular Anesthesiologists (ASE/SCA) standard views and other novel views we have described of the tricuspid (TV) and pulmonary valves (PV) offered superior incident angles to those included in the original 1999 ASE/SCA recommendations for comprehensive intraoperative TOE examination. We compared the acquisition feasibility and incident angles obtained by these views in 62 patients undergoing elective cardiac surgery, who received TOE monitoring as standard care. Overall, the 2013 ASE/SCA standard and novel views provided superior incident angles for the TV (28% and 66% of patients) whereas the 1999 ASE/SCA standard views provided superior incident angles for the PV (79% of patients, P <0.0001). The novel 90° mid-oesophageal modified bicaval view (90°MEMBC) and the 1999 ASE/SCA standard aortic arch short-axis view (AoArSAX) obtained best incident angles for the TV (mean [95% confidence interval] 13° [10°-16°]) and PV (5° [3°-7°]) respectively. PV view acquisition feasibility between the 1999 ASE/SCA standard, 2013 ASE/SCA standard and novel views was not significantly different (acquisition rate difference 11%, P ≥0.11). We conclude that the 2013 ASE/SCA TV standard and novel views obtained superior incident angles for the tricuspid, but not pulmonary valves. We recommend that intraoperative sonographers consider the use of these views, particularly when incident angles obtained with standard views are suboptimal. [ABSTRACT FROM AUTHOR]
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- 2016
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113. Decellularized fresh homografts for pulmonary valve replacement: a decade of clinical experience.
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Sarikouch, Samir, Horke, Alexander, Tudorache, Igor, Beerbaum, Philipp, Westhoff-Bleck, Mechthild, Boethig, Dietmar, Repin, Oleg, Maniuc, Liviu, Ciubotaru, Anatol, Haverich, Axel, and Cebotari, Serghei
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HOMOGRAFTS , *HEART valve transplantation , *CONGENITAL heart disease , *PROGENITOR cells , *THERAPEUTICS ,PULMONARY valve diseases - Abstract
OBJECTIVES: Decellularized homografts have shown auspicious early results when used for pulmonary valve replacement (PVR) in congenital heart disease. The first clinical application in children was performed in 2002, initially using pre-seeding with endogenous progenitor cells. Since 2005, only non-seeded, fresh decellularized allografts have been implanted after spontaneous recellularization was observed by several groups. METHODS: A matched comparison of decellularized fresh pulmonary homografts (DPHs) implanted for PVR with cryopreserved pulmonary homografts (CHs) and bovine jugular vein conduits (BJVs) was conducted. Patients' age at implantation, the type of congenital malformation, number of previous cardiac operations and number of previous PVRs were considered for matching purposes, using an updated contemporary registry of right ventricular outflow tract conduits (2300 included conduits, >12 000 patient-years). RESULTS: A total of 131 DPHs were implanted for PVR in the period from January 2005 to September 2015. Of the 131, 38 were implanted within prospective trials on DPH from October 2014 onwards and were therefore not analysed within this study. A total of 93 DPH patients (58 males, 35 females) formed the study cohort and were matched to 93 CH and 93 BJV patients. The mean age at DPH implantation was 15.8 ± 10.21 years (CH 15.9 ± 10.4, BJV 15.6 ± 9.9) and the mean DPH diameter was 23.9 mm (CH 23.3 ± 3.6, BJV 19.9 ± 2.9). There was 100% follow-up for DPH, including 905 examinations with a mean follow-up of 4.59 ± 2.76 years (CH 7.4 ± 5.8, BJV 6.4 ± 3.8), amounting to 427.27 patient-years in total (CH 678.3, BJV 553.0). Tetralogy-of-Fallot was the most frequent malformation (DPH 50.5%, CH 54.8%, BJV 68.8%). At 10 years, the rate of freedom of explantation was 100% for DPH, 84.2% for CH (P = 0.01) and 84.3% for BJV (P= 0.01); the rate of freedom from explantation and peak trans-conduit gradient =50 mmHg was 86% for DPH, 64% for CH (n.s.) and 49% for BJV (P < 0.001); the rate of freedom from infective endocarditis (IE) was 100% for DPH, 97.3 ± 1.9% within the matched CH patients (P = 0.2) and 94.3 ± 2.8% for BJV patients (P = 0.06). DPH valve annulus diameters converged towards normal Z-values throughout the observation period, in contrast to other valve prostheses (BJV). CONCLUSIONS: Mid-term results of DPH for PVR confirm earlier results of reduced re-operation rates compared with CH and BJV. [ABSTRACT FROM AUTHOR]
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- 2016
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114. Transcatheter Tricuspid Valve-in-Valve Implantation for the Treatment of Dysfunctional Surgical Bioprosthetic Valves: An International, Multicenter Registry Study.
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McElhinney, Doff B., Cabalka, Allison K., Aboulhosn, Jamil A., Eicken, Andreas, Boudjemline, Younes, Schubert, Stephan, Himbert, Dominique, Asnes, Jeremy D., Salizzoni, Stefano, Bocks, Martin L., Cheatham, John P., Momenah, Tarek S., Kim, Dennis W., Schranz, Dietmar, Meadows, Jeffery, Thomson, John D. R., Goldstein, Bryan H., Crittendon III, Ivory, Fagan, Thomas E., and Webb, John G.
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TRICUSPID valve , *BIOPROSTHESIS , *ARTIFICIAL implants , *ENDOCARDITIS , *CARDIAC catheterization , *COMPARATIVE studies , *PROSTHETIC heart valves , *HEART valve diseases , *LENGTH of stay in hospitals , *INTERNATIONAL relations , *LONGITUDINAL method , *RESEARCH methodology , *MEDICAL cooperation , *COMPLICATIONS of prosthesis , *RESEARCH , *EVALUATION research , *TREATMENT effectiveness , *ACQUISITION of data , *DIAGNOSIS ,PULMONARY valve diseases - Abstract
Background: Off-label use of transcatheter aortic and pulmonary valve prostheses for tricuspid valve-in-valve implantation (TVIV) within dysfunctional surgical tricuspid valve (TV) bioprostheses has been described in small reports.Methods and Results: An international, multicenter registry was developed to collect data on TVIV cases. Patient-related factors, procedural details and outcomes, and follow-up data were analyzed. Valve-in-ring or heterotopic TV implantation procedures were not included. Data were collected on 156 patients with bioprosthetic TV dysfunction who underwent catheterization with planned TVIV. The median age was 40 years, and 71% of patients were in New York Heart Association class III or IV. Among 152 patients in whom TVIV was attempted with a Melody (n=94) or Sapien (n=58) valve, implantation was successful in 150, with few serious complications. After TVIV, both the TV inflow gradient and tricuspid regurgitation grade improved significantly. During follow-up (median, 13.3 months), 22 patients died, 5 within 30 days; all 22 patients were in New York Heart Association class III or IV, and 9 were hospitalized before TVIV. There were 10 TV reinterventions, and 3 other patients had significant recurrent TV dysfunction. At follow-up, 77% of patients were in New York Heart Association class I or II (P<0.001 versus before TVIV). Outcomes did not differ according to surgical valve size or TVIV valve type.Conclusions: TVIV with commercially available transcatheter prostheses is technically and clinically successful in patients of various ages across a wide range of valve size. Although preimplantation clinical status was associated with outcome, many patients in New York Heart Association class III or IV at baseline improved. TVIV should be considered a viable option for treatment of failing TV bioprostheses. [ABSTRACT FROM AUTHOR]- Published
- 2016
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115. Meditative Movement as a treatment for Pulmonary Dysfunction in Flight Attendants Exposed to second-Hand cigarette smoke: study Protocol for a randomized trial.
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Payne, Peter, Fiering, Steven, Crane-Godreau, Mardi, and Zava, David
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THERAPEUTIC use of meditation ,PULMONARY valve diseases ,SMOKING ,THERAPEUTICS - Abstract
A study protocol is presented for the investigation of meditative movement (MM) as a treatment for pulmonary dysfunction in flight attendants (FA) who were exposed to second-hand cigarette smoke while flying before the smoking ban. The study will have three parts, some of which will run concurrently. The first is a data gathering and screening phase, which will gather data on pulmonary and other aspects of the health of FA, and will also serve to screen participants for the other phases. Second is an exercise selection phase, in which a variety of MM exercises will be taught, over a 16-week period, to a cohort of 20 FA. A subset of these exercises will be selected on the basis of participant feedback on effectiveness and compliance. Third is a 52-week randomized controlled trial to evaluate the effectiveness of a digitally delivered form of the previously selected exercises on a group of 20 FA, as compared with an attention control group. Outcome measures to be used in all three parts of the study include the 6-min walk test as a primary measure, as well as a range of biomarkers, tests, and questionnaires documenting hormonal, cardio-respiratory, autonomic, and affective state. [ABSTRACT FROM AUTHOR]
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- 2016
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116. A Novel 13-Segment Standardized Model for Assessment of Right Ventricular Function Using Two-Dimensional iRotate Echocardiography.
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McGhie, Jackie S., Menting, Myrthe E., Vletter, Wim B., Frowijn, René, Roos‐Hesselink, Jolien W., Soliman, Osama I. I., Zwaan, Heleen B., Geleijnse, Marcel L., and Bosch, Annemien E.
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HEART ventricle diseases , *BODY surface mapping , *CORONARY arteries , *ECHOCARDIOGRAPHY , *LONGITUDINAL method , *RIGHT heart ventricle , *PILOT projects , *INTER-observer reliability , *CASE-control method , *DATA analysis software , *DESCRIPTIVE statistics , *ANATOMY , *PHYSIOLOGY ,RESEARCH evaluation ,PULMONARY valve diseases - Abstract
Aims The aim of this study was to evaluate the feasibility of transthoracic two-dimensional (2D) iRotate, a new echo modality, to assess the whole right ventricle ( RV) from a single transducer position based on anatomic landmarks. Methods and Results The anatomic landmarks were first defined based on three-dimensional echocardiographic datasets using multiplane reconstruction analyses. Thereafter, we included 120 healthy subjects (51% male, age range 21-67 years). Using 2D iRotate, four views of the RV could be acquired based on these landmarks. The anterior, lateral, inferior wall (divided into three segments: basal-mid-apical), and right ventricular outflow tract ( RVOT) anterior wall of the RV were determined. The feasibility of visualization of RV segments and tricuspid annular plane systolic excursion ( TAPSE) and tissue Doppler imaging ( TDI) measurements were assessed. To evaluate this model for diseased RVs, a small pilot study of 20 patients was performed. In 98% of healthy subjects and 100% of patients, iRotate mode was feasible to assess the RV from one single transducer position. In total, 86% and 95%, respectively, of the RV segments could be visualized. The visualization of the RVOT anterior wall was worse 23% and 75%, respectively. TAPSE and TDI measurements on all four views were feasible 93% and 92%, respectively, of the healthy subjects and in 100% of the patients. Conclusion With 2D iRotate, a comprehensive evaluation of the entire normal and diseased RV is feasible from a fixed transducer position based on anatomic landmarks. This is less time-consuming than the multiview approach and enhances accuracy of RV evaluation. Imaging of the RVOT segment remains challenging. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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117. Differential Effect of the Ratio of Right Ventricular Volume to Left Ventricular Volume in Children with Repaired Tetralogy of Fallot.
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Yao, Qiong, Hu, Xi-hong, Shen, Quan-li, Qiao, Zhong-wei, Pa, Mi-er, Qian, Bin, Yan, Wei-li, and Huang, Guo-ying
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RIGHT heart ventricle , *LEFT heart ventricle , *TETRALOGY of Fallot , *MULTIVARIATE analysis , *SURGERY ,PULMONARY valve diseases - Abstract
We aimed to compare the diagnostic value of indexed right ventricular end-diastolic volume (RVEDVi) and the ratio of right ventricle volume to left ventricle volume (RV/LV ratio) in prediction of the severity of pulmonary regurgitation (PR) expressed as the PR fraction (PRF) after surgery of tetralogy of Fallot (TOF). Forty-one patients with repaired TOF were included in the study. RVEDVi, LVEDVi, RV/LV ratio, PRF and ejection fraction were measured with magnetic resonance imaging. A PRF of more than 20% was considered significant. The predictive capability of two markers (RVEDVi and RV/LV ratio) for significant PR was compared using multivariate linear regression analysis and receiver operating characteristic (ROC) analysis. Both the RV/LV ratio and RVEDVi showed a correlation with PRF (r = 0.526/0.321, p = 0.001/0.041) in the correlation analysis, but in multivariate regression analysis the only independent predictor of PRF was the RV/LV ratio (F = 14.890, p = 0.001). ROC analysis revealed that a better discrimination of significant PR (>20%) from slight types (=20%) PR can be reached with the RV/LV ratio than RVEDVi (AUC = 0.805/0.709, p = 0.01). The RV/LV ratio was better than RVEDVi at differentiating mild from moderate PR (p = 0.006 vs. p = 0.153), and proved superior over RVEDVi in predicting PR based on the PRF criterion. © 2015 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Published
- 2016
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118. Robust Cardiac Function Assessment in 4D PC-MRI Data of the Aorta and Pulmonary Artery.
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Köhler, Benjamin, Preim, Uta, Grothoff, Matthias, Gutberlet, Matthias, Fischbach, Katharina, and Preim, Bernhard
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SCIENTIFIC visualization , *PHASE contrast magnetic resonance imaging , *AORTIC valve insufficiency , *DIAGNOSTIC imaging research , *DIGITAL image processing , *DIAGNOSIS ,PULMONARY valve diseases - Abstract
Four-dimensional phase-contrast magnetic resonance imaging (4D PC-MRI) allows the non-invasive acquisition of time-resolved, 3D blood flow information. Stroke volumes (SVs) and regurgitation fractions (RFs) are two of the main measures to assess the cardiac function and severity of valvular pathologies. The flow rates in forward and backward direction through a plane above the aortic or pulmonary valve are required for their quantification. Unfortunately, the calculations are highly sensitive towards the plane's angulation since orthogonally passing flow is considered. This often leads to physiologically implausible results. In this work, a robust quantification method is introduced to overcome this problem. Collaborating radiologists and cardiologists were carefully observed while estimating SVs and RFs in various healthy volunteer and patient 4D PC-MRI data sets with conventional quantification methods, that is, using a single plane above the valve that is freely movable along the centerline. By default it is aligned perpendicular to the vessel's centerline, but free angulation (rotation) is possible. This facilitated the automation of their approach which, in turn, allows to derive statistical information about the plane angulation sensitivity. Moreover, the experts expect a continuous decrease of the blood flow volume along the vessel course. Conventional methods are often unable to produce this behaviour. Thus, we present a procedure to fit a monotonous function that ensures such physiologically plausible results. In addition, this technique was adapted for the usage in branching vessels such as the pulmonary artery. The performed informal evaluation shows the capability of our method to support diagnosis; a parameter evaluation confirms the robustness. Vortex flow was identified as one of the main causes for quantification uncertainties. [ABSTRACT FROM AUTHOR]
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- 2016
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119. Endurance Training on Congenital Valvular Regurgitation: An Athlete Case Series.
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HOYT JR., WALTER JORDAN, DEAN, PETER N., JOHN, ANITHA S., GIMPLE, LAWRENCE W., MISTRY, DILAAWAR J., and BATTLE, ROBERT W.
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PHYSIOLOGICAL adaptation , *AORTIC valve insufficiency , *HEART valve diseases , *CASE studies , *PHYSICAL fitness , *PHYSICAL training & conditioning , *ELITE athletes ,PULMONARY valve diseases - Abstract
Background: Both intense endurance training and valvular regurgitation place a volume load on the right and left ventricles, potentially leading to dilation, but their effects in combination are not well-known. Purpose: The purpose of this case series is to describe the combined volume load of intense endurance athletic training and regurgitant valvular disease as well as the challenging assessment of each component's cardiovascular effect. Methods: In this article, the clinical course of three elite endurance athletes with congenital valvular disease were reviewed. Results: A swimmer with aortic regurgitation, a cyclist with aortic regurgitation, and a cyclist with pulmonary regurgitation were found to have severe dilation of the associated ventricles despite continuing to train at an elite level without symptoms. Conclusions: Because of the cumulative effects of endurance training and valvular regurgitation, each athlete manifested ventricular dilation out of proportion to their valvular disease and symptoms. Although the effects of congenital valvular disease and athletic remodeling on ventricular dilation have been thoroughly studied individually, their cumulative effect is not well understood. This complicates the assessment of athletes with valvular regurgitation and underscores the need for athlete-specific recommendations for valve replacement. [ABSTRACT FROM AUTHOR]
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- 2016
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120. Isolated Pulmonary Valve Endocarditis.
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Chowdhury, Mohammed Andaleeb and Moukarbel, George V.
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ENDOCARDITIS , *DIAGNOSIS of endocarditis , *TRANSESOPHAGEAL echocardiography , *HEART diseases , *DIAGNOSIS , *PATIENTS ,PULMONARY valve diseases - Abstract
Endocarditis of only the pulmonary valve is a very rare finding and is often missed during echocardiographic evaluation due to limited views of the pulmonary valve and a low index of suspicion. We report 2 cases of pulmonary valve endocarditis (PVE), highlighting the importance of echocardiography in the assessment of the infected pulmonary valve. In addition, we review the published case reports of isolated PVE from 1979 to 2013 in order to study the role of echocardiography in the diagnosis of pulmonary valve masses. © 2015 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
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- 2016
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121. Thrombolytic Therapy for Right-Sided Mechanical Pulmonic and Tricuspid Valves: The Largest Survival Analysis to Date.
- Author
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Taherkhani, Maryam, Hashemi, Seyed Reza, Hekmat, Manouchehr, Safi, Morteza, Taherkhani, Adineh, and Movahed, Mohammad Reza
- Subjects
- *
THROMBOLYTIC therapy , *THROMBOSIS , *CARDIOVASCULAR disease treatment , *TRICUSPID valve diseases , *HEART diseases , *THERAPEUTICS ,PULMONARY valve diseases - Abstract
Data regarding thrombolytic treatment of right-sided mechanical valve thrombosis are almost nonexistent, and all current guidelines arise from very small case series. We retrospectively studied the in-hospital and long-term outcome data of a larger series of patients who had received, from September 2005 through June 2012, thrombolytic therapy for right-sided mechanical pulmonary valve or tricuspid valve thrombosis. We identified 16 patients aged 8-67 years who had undergone thrombolytic therapy for definite thrombotic mechanical valve obstruction in the tricuspid or pulmonary valve position (8 in each position). All study patients except one had subtherapeutic international normalized ratios. The 8 patients with pulmonary mechanical valve thrombosis had a 100% response rate to thrombolytic therapy, and their in-hospital survival rate was also 100%. The 8 patients with tricuspid mechanical valve thrombosis had a 75% response rate to thrombolytic therapy, with an in-hospital survival rate of 87.5%. The one-year survival rate for mechanical valve thrombosis treated with thrombolytic therapy (whether pulmonary or tricuspid) was 87.5%. On the basis of our data, we recommend that thrombolytic therapy remain the first-line therapy for right-sided mechanical valve thrombosis in adults or children--including children with complex congenital heart disease and patients with mechanical pulmonary valve thrombosis. Surgery should be reserved for patients in whom this treatment fails. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
122. The Utility of Intracardiac Echocardiography Following Melody™ Transcatheter Pulmonary Valve Implantation.
- Author
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Whiteside, Wendy, Pasquali, Sara, Yu, Sunkyung, Bocks, Martin, Zampi, Jeffrey, and Armstrong, Aimee
- Subjects
- *
ECHOCARDIOGRAPHY , *HEALTH outcome assessment , *CORONARY angiography , *DISEASE management , *THERAPEUTICS ,PULMONARY valve diseases - Abstract
The aim of this study was to determine the utility of intracardiac echocardiography (ICE) in assessing Melody™ transcatheter pulmonary valve (TPV) function immediately following valve implantation. ICE is used increasingly in percutaneous cardiac interventions. At our center, ICE is routinely utilized to evaluate valve function following Melody TPV implantation, but the utility of this practice remains unclear. A retrospective review of all Melody valves placed in the right ventricular outflow tract from April 2010 to September 2013 was performed. The clinical utility of ICE was described, along with the relationship between ICE data and traditional hemodynamic/angiographic data. ICE was performed in 54 cases and provided excellent Melody TPV visualization with no complications. ICE did not change clinical management but did provide supplemental information in two cases. In one case, angiography showed severe catheter-related Melody insufficiency. Subsequent ICE confirmed no insufficiency and prevented the need for additional angiography. In the second case, ICE allowed characterization of the mechanism of a residual gradient. ICE did not detect any clinically significant paravalvar leaks or valvar insufficiency not seen by angiography. The peak catheterization gradient was more closely approximated by the mean ICE gradient (median difference −7.4 % between measurements) than by the peak ICE gradient (median difference 58.3 %; p < 0.0001). ICE provides excellent and safe visualization following Melody TPV implantation but did not provide new clinical information impacting management in this series. Selective use of ICE in cases with more than expected valve insufficiency or larger than expected residual gradients may streamline use while maintaining optimal clinical outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
123. Recent Studies from University of Maryland Add New Data to Pulmonary Atresia (Palliation of a Heterotaxy Single Ventricle Neonate With Pulmonary Atresia and Obstructed Tapvr).
- Subjects
PULMONARY atresia ,HEART valve diseases ,SCIMITAR syndrome ,PULMONARY valve diseases ,CONGENITAL heart disease - Abstract
Keywords: Baltimore; State:Maryland; United States; North and Central America; Cardiology; Cardiovascular; Cardiovascular Abnormalities; Congenital Abnormalities; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Valve Diseases and Conditions; Pulmonary Atresia; Risk and Prevention; Surgery; Vascular Malformations EN Baltimore State:Maryland United States North and Central America Cardiology Cardiovascular Cardiovascular Abnormalities Congenital Abnormalities Health and Medicine Heart Disease Heart Disorders and Diseases Heart Valve Diseases and Conditions Pulmonary Atresia Risk and Prevention Surgery Vascular Malformations 563 563 1 04/10/23 20230410 NES 230410 2023 APR 10 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- Fresh data on Heart Disorders and Diseases - Pulmonary Atresia are presented in a new report. Keywords for this news article include: Baltimore, Maryland, United States, North and Central America, Cardiology, Cardiovascular, Cardiovascular Abnormalities, Congenital Abnormalities, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Pulmonary Atresia, Risk and Prevention, Surgery, Vascular Malformations, University of Maryland. Baltimore, State:Maryland, United States, North and Central America, Cardiology, Cardiovascular, Cardiovascular Abnormalities, Congenital Abnormalities, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Pulmonary Atresia, Risk and Prevention, Surgery, Vascular Malformations. [Extracted from the article]
- Published
- 2023
124. Nippon Veterinary and Life Science University Reports Findings in Veterinary Medicine (Prognostic value of pulmonary vascular resistance estimated by echocardiography in dogs with myxomatous mitral valve disease and pulmonary hypertension).
- Subjects
PULMONARY hypertension ,LIFE sciences ,PULMONARY valve diseases ,SCIENCE journalism ,VETERINARY medicine ,MITRAL valve - Abstract
Japan, Asia, Veterinary Medicine, Tokyo Keywords: Tokyo; Japan; Asia; Veterinary Medicine EN Tokyo Japan Asia Veterinary Medicine 31 31 1 04/10/23 20230410 NES 230410 2023 APR 10 (NewsRx) -- By a News Reporter-Staff News Editor at Veterinary Week -- New research on Veterinary Medicine is the subject of a report. [Extracted from the article]
- Published
- 2023
125. Research from Southern Medical University in Pulmonary Atresia Provides New Insights (Should Prenatal Chromosomal Microarray Analysis Be Offered for Pulmonary Atresia? A Single-Center Retrospective Study in China).
- Subjects
HEART valve diseases ,PULMONARY atresia ,PULMONARY valve diseases ,MATERNAL age ,RETROSPECTIVE studies ,HUMAN abnormalities ,HEART diseases - Abstract
Asia, Cardiology, Cardiovascular, Cardiovascular Abnormalities, China, Congenital Abnormalities, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Pulmonary Atresia, Risk and Prevention, Vascular Malformations Keywords: Asia; Cardiology; Cardiovascular; Cardiovascular Abnormalities; China; Congenital Abnormalities; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Valve Diseases and Conditions; Pulmonary Atresia; Risk and Prevention; Vascular Malformations EN Asia Cardiology Cardiovascular Cardiovascular Abnormalities China Congenital Abnormalities Health and Medicine Heart Disease Heart Disorders and Diseases Heart Valve Diseases and Conditions Pulmonary Atresia Risk and Prevention Vascular Malformations 732 732 1 04/03/23 20230404 NES 230404 2023 APR 3 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- New research on pulmonary atresia is the subject of a new report. Research from Southern Medical University in Pulmonary Atresia Provides New Insights (Should Prenatal Chromosomal Microarray Analysis Be Offered for Pulmonary Atresia?. [Extracted from the article]
- Published
- 2023
126. New Pulmonary Atresia Study Findings Have Been Reported by Investigators at Wolfson Medical Center [Prenatal Diagnosis of Major Aortopulmonary Collateral Arteries (Mapca) In Fetuses With Pulmonary Atresia With Ventricular Septal Defect and...].
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PULMONARY atresia ,VENTRICULAR septal defects ,PRENATAL diagnosis ,HEART valve diseases ,MEDICAL centers ,PULMONARY valve diseases - Abstract
Keywords for this news article include: Holon, Israel, Asia, Cardiology, Cardiovascular, Cardiovascular Abnormalities, Congenital Abnormalities, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Pulmonary Atresia, Vascular Malformations, Ventricular Septal Defect, Wolfson Medical Center. Keywords: Holon; Israel; Asia; Cardiology; Cardiovascular; Cardiovascular Abnormalities; Congenital Abnormalities; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Valve Diseases and Conditions; Pulmonary Atresia; Vascular Malformations; Ventricular Septal Defect EN Holon Israel Asia Cardiology Cardiovascular Cardiovascular Abnormalities Congenital Abnormalities Health and Medicine Heart Disease Heart Disorders and Diseases Heart Valve Diseases and Conditions Pulmonary Atresia Vascular Malformations Ventricular Septal Defect 524 524 1 03/27/23 20230330 NES 230330 2023 MAR 27 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- Fresh data on Heart Disorders and Diseases - Pulmonary Atresia are presented in a new report. [Extracted from the article]
- Published
- 2023
127. Studies from Medical University of South Carolina Update Current Data on Pulmonary Atresia (The Utility of Ct Angiography In Neonates With Pulmonary Atresia With Intact Ventricular Septum and Concern for Right Ventricular Dependent Coronary...).
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PULMONARY atresia ,VENTRICULAR septum ,ANGIOGRAPHY ,HEART valve diseases ,PULMONARY valve diseases ,CARDIAC catheterization ,MYOCARDIAL perfusion imaging ,PEDIATRIC cardiology - Abstract
The news correspondents obtained a quote from the research from the Medical University of South Carolina, "Cardiac computed tomography (CCT) potentially provides a less invasive imaging option for therapeutic planning in this group of patients. Keywords: Charleston; State:South Carolina; United States; North and Central America; Angiography; Cardiology; Cardiovascular; Cardiovascular Abnormalities; Cardiovascular Diagnostic Techniques; Catheterization; Congenital Abnormalities; Health and Medicine; Heart Catheterization; Heart Disease; Heart Disorders and Diseases; Heart Valve Diseases and Conditions; Pulmonary Atresia; Vascular Malformations EN Charleston State:South Carolina United States North and Central America Angiography Cardiology Cardiovascular Cardiovascular Abnormalities Cardiovascular Diagnostic Techniques Catheterization Congenital Abnormalities Health and Medicine Heart Catheterization Heart Disease Heart Disorders and Diseases Heart Valve Diseases and Conditions Pulmonary Atresia Vascular Malformations 903 903 1 03/23/23 20230320 NES 230320 2023 MAR 20 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- Investigators publish new report on Heart Disorders and Diseases - Pulmonary Atresia. Charleston, State:South Carolina, United States, North and Central America, Angiography, Cardiology, Cardiovascular, Cardiovascular Abnormalities, Cardiovascular Diagnostic Techniques, Catheterization, Congenital Abnormalities, Health and Medicine, Heart Catheterization, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Vascular Malformations, Pulmonary Atresia. [Extracted from the article]
- Published
- 2023
128. Study Results from Keio University School of Medicine in the Area of Pulmonary Atresia Published (Clinical Characteristics of Coronary-to-Pulmonary Artery Fistula in Patients with Pulmonary Atresia and Ventricular Septal Defect).
- Subjects
PULMONARY atresia ,VENTRICULAR septal defects ,PULMONOLOGY ,HEART valve diseases ,FISTULA ,PULMONARY valve diseases - Abstract
Keywords: Angiology; Cardiology; Cardiovascular; Cardiovascular Abnormalities; Congenital Abnormalities; Health and Medicine; Heart Disease; Heart Disorders and Diseases; Heart Valve Diseases and Conditions; Pulmonary Artery; Pulmonary Atresia; Vascular Malformations; Ventricular Septal Defect EN Angiology Cardiology Cardiovascular Cardiovascular Abnormalities Congenital Abnormalities Health and Medicine Heart Disease Heart Disorders and Diseases Heart Valve Diseases and Conditions Pulmonary Artery Pulmonary Atresia Vascular Malformations Ventricular Septal Defect 2023 FEB 6 (NewsRx) -- By a News Reporter-Staff News Editor at Heart Disease Weekly -- Researchers detail new data in pulmonary atresia. Angiology, Cardiology, Cardiovascular, Cardiovascular Abnormalities, Congenital Abnormalities, Health and Medicine, Heart Disease, Heart Disorders and Diseases, Heart Valve Diseases and Conditions, Pulmonary Artery, Vascular Malformations, Pulmonary Atresia, Ventricular Septal Defect. [Extracted from the article]
- Published
- 2023
129. ROLE OF COMPUTED TOMOGRAPHY (CT) ANGIOGRAPHY IN DETECTION OF AORTOPULMONARY WINDOW (APW): REPORT OF A RARE ENTITY.
- Author
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Khan, Muhammad Salman, Salam, Abdus, Awais, Muhammad Bin, Mustafa, Syed Farrukh, and Nadeem, Naila
- Subjects
- *
CARDIOGRAPHIC tomography , *CORONARY arterial radiography , *CONGENITAL heart disease diagnosis , *AORTIC valve diseases ,PULMONARY valve diseases - Abstract
A 3 months old female child referred for scans at the department of radiology with suspicion of a congenital heart disease. A CT angiography was performed, which revealed an abnormal communication between the proximal aorta and the pulmonary trunk in the presence of separate aortic and pulmonary valves representing aortopulmonary window. This case shows the importance of CT angiography in the diagnosis and classification of aortopulmonary window as it gives a complete overview of the anatomy which can subsequently make planning for surgery easier. [ABSTRACT FROM AUTHOR]
- Published
- 2018
130. The Effects of Pulmonary Valve Replacement for Severe Pulmonary Regurgitation on Exercise Capacity and Cardiac Function.
- Author
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Ho, Jason, Schamberger, Marcus, Hurwitz, Roger, Johnson, Tiffanie, Sterrett, Lauren, and Ebenroth, Eric
- Subjects
- *
RIGHT heart ventricle , *AORTIC valve insufficiency , *MAGNETIC resonance imaging , *OXYGEN consumption , *POSTOPERATIVE period ,PULMONARY valve diseases - Abstract
Patients may develop hemodynamic abnormalities after right ventricular outflow tract (RVOT) repair. Re-intervention timing remains a dilemma. This study evaluates exercise capacity and RV function before and after intervention using age-related comparisons. Twenty-six patients with severe pulmonary regurgitation (PR) after initial repair scheduled for pulmonary valve replacement (PVR) were enrolled. Metabolic treadmill testing (EST) and MRI were obtained before and after surgery. EST results were compared with matched controls. Preoperative exercise time and peak oxygen consumption (VO max) were significantly diminished compared with controls but were not significantly different postoperatively. The patients were then split into age-related cohorts. When comparing pre-PVR and post-PVR exercise time and VO max among themselves, neither cohort showed significant differences. However, patients younger than 25 years had better postoperative results, an age-related difference not seen in the controls. Preoperative MRI showed significantly dilated RV, PR, and low normal function. After PVR, the right to left ventricular end-diastolic volume ratio (RVEDV:LVEDV) and pulmonary artery regurgitant fraction (RF) significantly decreased. There was no change in ventricular ejection fractions (EF). Severe PR, decreased RVEF, and RV dilation can significantly diminish exercise capacity. PVR improves RVEDV:LVEDV and RF, but not EF. Younger patients had better exercise capacity that was maintained postoperatively. This age-related difference was not seen in the controls, indicating that earlier intervention may preserve exercise capacity. Serial ESTs in patients with severe PR following RVOT repair may identify deteriorating exercise capacity as an early indicator for the need for PVR. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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- View/download PDF
131. Long-Term Outcome of Mechanical Pulmonary Valve Replacement in 121 Patients with Congenital Heart Disease.
- Author
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Dehaki, Maziar Gholampour, Ghavidel, Alireza Alizadeh, Omrani, Gholamreza, and Javadikasgari, Hoda
- Subjects
- *
PULMONARY stenosis , *CONGENITAL heart disease , *THROMBOSIS , *CARDIOVASCULAR diseases , *STREPTOKINASE , *PLASMINOGEN activators ,PULMONARY valve diseases - Abstract
Background A tissue valve is the prosthesis of choice in the majority of children and adults requiring pulmonary valve replacement (PVR). Mechanical valves, on the other hand, are more durable but require anticoagulation therapy and carry the elevated risk of thrombosis. The aim of this study was to investigate the long-term outcomes of mechanical prosthetic valves in a single referral tertiary center. Patients and Methods Recorded data of 121 patients who underwent mechanical PVR between April 2003 and April 2013 at our center were reviewed, retrospectively. Eighty four patients (69.4%) were male and their mean age was 23.12 ± 7.86 years. Tetralogy of Fallot was the most common diagnosis (n = 109). Complete follow-up was performed for all patients (mean 7.02 ± 1.90 years). Results Nobody died and no significant bleeding event was detected during follow-up. Mechanical valve malfunction happened in 10 patients (8.3%) while in 1 of them malfunction happened because of pannus formation and in the remaining 9 because of thrombosis. Just one of the thrombotic events could not be treated with streptokinase and required reoperation. Freedom from reoperation rates were 100, 99, and 98% at 1, 5, and 10 years, respectively; freedom from valve thrombosis event rates were 100, 93, and 91% at 1, 5, and 10 years, respectively; and freedom from bleeding event rates was 98% at 1, 5, and 10 years. Conclusion Mechanical prosthetic valves demonstrated excellent durability and a lowrisk of valve thrombosis at the pulmonary position when patients are adequately anticoagulated. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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- View/download PDF
132. The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF).
- Author
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Bigdelian, Hamid, Mardani, Davoud, and Sedighi, Mohsen
- Subjects
CARDIAC patients ,HEMODYNAMICS ,HOSPITAL admission & discharge ,INTENSIVE care units ,MEDICAL care ,PATIENTS ,PREOPERATIVE care ,TETRALOGY of Fallot ,DATA analysis ,PULMONARY valve diseases ,DESCRIPTIVE statistics - Published
- 2015
- Full Text
- View/download PDF
133. Native Pulmonic Valve Endocarditis due to Mycobacterium fortuitum: A Case Report and Literature Review.
- Author
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Mulhall, Aaron M. and Hebbeler-Clark, Renee S.
- Subjects
- *
ENDOCARDITIS , *MYCOBACTERIUM , *SYSTEMATIC reviews , *MEDICAL care ,PULMONARY valve diseases - Abstract
Endocarditis secondary to Mycobacterium fortuitum is a rare entity often involving prosthetic valves and rarely native valves. Pulmonic valve endocarditis secondary to any organism is rare. We report the first case of native pulmonic valve endocarditis secondary to M. fortuitum and a literature review of native valve M. fortuitum endocarditis. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
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134. Clinical Utility of the Plasma Brain Natriuretic Peptide Level in Monitoring Tetralogy of Fallot Patients over the Long Term After Initial Intracardiac Repair: Considerations for Pulmonary Valve Replacement.
- Author
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Kitagawa, Atsushi, Oka, Norihiko, Kimura, Sumito, Ando, Hisashi, Honda, Takashi, Takanashi, Manabu, Mineo, Eri, Miyaji, Kagami, and Ishii, Masahiro
- Subjects
- *
TETRALOGY of Fallot , *BRAIN natriuretic factor , *NATRIURETIC peptides , *ECHOCARDIOGRAPHY , *BLOOD plasma ,PULMONARY valve diseases - Abstract
Clinicians are currently encountering an increasing number of patients in the long-term period after tetralogy of Fallot (TOF) repair presenting with pulmonary valve regurgitation (PR) or right ventricular (RV) dysfunction. The purpose of this study was to evaluate the clinical utility of the plasma brain natriuretic peptide (BNP) level and consider surgical indications and timing of pulmonary valve replacement (PVR). We examined 33 patients (21 males, 12 females, mean age 14.5 ± 2.8 years) who underwent TOF repair at Kitasato University Hospital. All patients were evaluated using echocardiography and blood sampling. The mean age at the time of initial repair was 1.3 ± 0.7 years. The patients with moderate-severe PR exhibited significantly higher plasma BNP levels than the patients with trivial-mild PR (mean 37.5 ± 33.1 vs. 17.3 ± 6.6 pg/ml, p = 0.013). The mean plasma BNP level with cardiac symptoms was higher than that observed in the patients without any symptoms (71.4 ± 46.1 vs. 25.0 ± 14.0 pg/ml, p = 0.005). The mean BNP level was significantly decreased after PVR (71.3 ± 46.1-26.1 ± 13.2 pg/ml, p = 0.009), and the plasma BNP level was found to be positively correlated with the RV end-diastolic pressure ( r = 0.851; p = 0.008). The optimal BNP cut-off value for considering PVR was 32.15 pg/ml (sensitivity, 85.7 %; specificity, 83.3 %). The plasma BNP level may become a useful diagnostic tool for considering the indications and optimal timing of PVR over the long term after TOF repair. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
135. Changes in Speckle Tracking Echocardiography Measures of Ventricular Function after Percutaneous Implantation of the Edwards SAPIEN Transcatheter Heart Valve in the Pulmonary Position.
- Author
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Chowdhury, Shahryar M., Hijazi, Ziyad M., Rhodes, John F., Kar, Saibal, Makkar, Raj, Mullen, Michael, Cao, Qi‐Ling, Mandinov, Lazar, Buckley, Jason, Pietris, Nicholas P., and Shirali, Girish S.
- Subjects
- *
HEART ventricles , *MYOCARDIUM physiology , *ECHOCARDIOGRAPHY , *CONGENITAL heart disease , *ANALYSIS of variance , *PROSTHETIC heart valves , *HEART valve diseases , *LONGITUDINAL method , *MEDICAL cooperation , *RESEARCH , *RESEARCH funding , *STATISTICS , *DATA analysis , *INTER-observer reliability , *REPEATED measures design , *DATA analysis software , *DESCRIPTIVE statistics , *DIAGNOSIS , *SURGERY , *PHYSIOLOGY ,PULMONARY valve diseases ,RESEARCH evaluation - Abstract
Background Patients with free pulmonary regurgitation or mixed pulmonary stenosis and regurgitation and severely dilated right ventricles (RV) show little improvement in ventricular function after pulmonary valve replacement when assessed by traditional echocardiographic markers. We evaluated changes in right and left ventricular (LV) function using speckle tracking echocardiography in patients after SAPIEN transcatheter pulmonary valve (TPV) placement. Methods Echocardiograms were evaluated at baseline, discharge, 1 and 6 months after TPV placement in 24 patients from 4 centers. Speckle tracking measures of function included peak longitudinal strain, strain rate, and early diastolic strain rate. RV fractional area change, tricuspid annular plane systolic excursion, and left ventricular LV ejection fraction were assessed. Routine Doppler and tissue Doppler velocities were measured. Results At baseline, all patients demonstrated moderate to severe pulmonary regurgitation; this improved following TPV placement. No significant changes were detected in conventional measures of RV or LV function at 6 months. RV longitudinal strain (−16.9% vs. −19.6%, P < 0.01), strain rate (−0.87 s−1 vs. −1.16 s−1, P = 0.01), and LV longitudinal strain (−16.2% vs. −18.2%, P = 0.01) improved between baseline and 6 month follow-up. RV early diastolic strain rate, LV longitudinal strain rate and early diastolic strain rate showed no change. Conclusion Improvements in RV longitudinal strain, strain rate, and LV longitudinal strain are seen at 6 months post-TPV. Diastolic function does not appear to change at 6 months. Speckle tracking echocardiography may be more sensitive than traditional measures in detecting changes in systolic function after TPV implantation. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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136. Pulmonary Annulus Preservation Lowers the Risk of Late Postoperative Pulmonary Valve Implantation After the Repair of Tetralogy of Fallot.
- Author
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Kim, Gwan, Han, Seungbong, and Yun, Tae-Jin
- Subjects
- *
PULMONARY valve , *PULMONARY artery , *TETRALOGY of Fallot , *HEART valve prosthesis implantation , *SURGERY ,PULMONARY valve diseases - Abstract
The long-term benefits of pulmonary annulus preservation in tetralogy of Fallot (ToF) repair in patients with a marginally small pulmonary annulus are controversial. We sought to determine whether pulmonary annulus preservation (AP) is superior to transannular patching (TAP) in lowering the risk of pulmonary valve implantation (PVI) long after the repair of ToF. Of the 255 patients who underwent total correction of ToF during infancy between January 1989 and December 2005, 114 patients (AP group = 57, TAP group = 57) were selected by propensity score matching for various preoperative variables, such as age and body weight at operation, sex, pulmonary artery size, pre-repair palliation, anatomical types of ventricular septal defect, and Z-score of pulmonary valve annulus diameter (PVA-Z). The PVA-Z of the AP and TAP groups were −2.3 ± 1.3 and −2.1 ± 1.3, respectively ( p = 0.547). The time to PVI was compared between the two groups. The median follow-up duration was 146 months (AP group: 141 months, TAP group: 147 months; p = 0.191). During the follow-up periods, there were 12 reoperations for the relief of right ventricular outflow tract obstruction (RVOTO), eight PVIs, and three late deaths. While freedom from reoperation for RVOTO was comparable between the two groups ( p = 0.182), freedom from PVI at postoperative 15 years was significantly lower in the TAP group than in the AP group (74 and 100 %, p = 0.015). In repairing ToF with marginally small pulmonary valve annulus, AP is associated with a lower risk of late postoperative PVI. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
137. Evaluation of Right Ventricular Function in Adults with Congenital Heart Defects.
- Author
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Bussadori, Claudio, Salvo, Giovanni Di, Pluchinotta, Francesca R., Piazza, Luciane, Gaio, Giampiero, Russo, Maria Giovanna, and Carminati, Mario
- Subjects
- *
ECHOCARDIOGRAPHY , *RIGHT heart ventricle , *ATRIAL septal defects , *CONGENITAL heart disease , *POSTOPERATIVE care , *TETRALOGY of Fallot , *ADULTS , *ANATOMY , *PHYSIOLOGY ,PULMONARY valve diseases - Abstract
The right ventricle ( RV) is of lesser importance in acquired heart disease, but its role is of increasing importance in congenital heart disease ( CHD). Despite major progress being made, precise measurements of the RV are challenging because of its peculiar anatomical structure that is not adaptable to any planar geometrical assumption. This is particularly true in adult patients with CHD where the RV shape eludes any standardization, it may assume various morphologies, and its modality of contraction depends on previous surgical treatment and/or pathophysiological conditions. However, reliable and repeatable quantification of RV dimensions and function for these patients are essential to provide appropriate timing for intervention to optimize outcomes. In this population, echocardiographic evaluation should not be limited to an observational and subjective functional assessment of the RV but must provide quantitative values repeatable and clinically reliable to help the decision-making process. The aim of this review was to discuss the echocardiographic approach to the RV in adult patients with CHD in general and in specific cases of pressure or volume overload. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
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138. Ross procedure: is the root replacement technique superior to the sub-coronary implantation technique? Long-term results.
- Author
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Berdajs, Denis A., Muradbegovic, Mirza, Haselbach, Daniel, Kofmehl, Reto, Steurer, Johann, Ferrari, Enrico, Held, Ulrike, and von Segesser, Ludwig K.
- Subjects
- *
HEART valve surgery , *AORTIC valve diseases , *CARDIAC patients , *CONFIDENCE intervals ,PULMONARY valve diseases - Abstract
There is controversy over the use of the Ross procedure with regard to the sub-coronary and root replacement technique and its long-term durability. A systematic review of the literature may provide insight into the outcomes of these two surgical subvariants. A systematic review of reports between 1967 and February 2013 on sub-coronary and root replacement Ross procedures was undertaken. Twenty-four articles were included and divided into (i) sub-coronary technique and (ii) root replacement technique. The 10-year survival rate for a mixed-patient population in the sub-coronary procedure was 87.3% with a 95% confidence interval (CI) of 79.7–93.4 and 89.1% (95% CI, 85.3–92.1) in the root replacement technique category. For adults, it was 94 vs 95.3% (CI, 88.9–98.1) and in the paediatric series it was 90 vs 92.7% (CI, 86.9–96.0), respectively. Freedom from reoperation at 10 years was, in the mixed population, 83.3% (95% CI, 69.9–93.4) and 93.3% (95% CI, 89.4–95.9) for sub-coronary versus root replacement technique, respectively. In adults, it was 98 vs 91.2% (95% CI, 82.4–295.8), and in the paediatric series 93.3 vs 92.0% (95% CI, 86.1–96.5) for sub-coronary versus root replacement technique, respectively. The Ross procedure arguably has satisfactory results over 5 and 10 years for both adults and children. The results do not support the advantages of the sub-coronary technique over the root replacement technique. Root replacement was of benefit to patients undergoing reoperations on neoaorta and for long-term survival in mixed series. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
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139. Isolated pulmonary valve infective endocarditis in a middle aged man caused by Candida albicans: a case report.
- Author
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Devathi, Sudhakar, Curry, Bryan, and Doshi, Saumil
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- *
ENDOCARDITIS , *INVASIVE candidiasis , *BRONCHOALVEOLAR lavage , *ENDOCARDIUM diseases , *CANDIDA albicans ,PULMONARY valve diseases - Abstract
Background Pulmonary valve endocarditis without the involvement of other valves represents 1.5-2% of all cases of infective endocarditis. Isolated pulmonary valve endocarditis caused by Candida is extremely rare with only one reported case in the literature and none reported in the United States. Guidelines for management of Candida endocarditis recommend a combination of medical and surgical therapy. Case presentation A 61-year-old homeless male presented with fever, cough and shortness of breath. He was urgently intubated for hypoxia. He was initially diagnosed with pneumonia but did not improve with empiric antibacterial therapy. Candida species were isolated from bronchoalveolar lavage fluid and the patient eventually developed persistent C. albicans bloodstream infection. On further workup he was found to have infective endocarditis with a large vegetation across the pulmonary valve. No other valves were involved. He was treated with intravenous antifungal therapy for eight weeks. Valvular surgery was not performed. Follow up echocardiography after completion of therapy did not show any vegetations and the patient clinically improved. Conclusion This is the second reported case of isolated pulmonary valve endocarditis caused by Candida and the first to be successfully managed with antifungal therapy alone. Pulmonary valve endocarditis should be considered in cases of pneumonia with Candida and persistent fungemia. While surgery should be considered in all cases of Candida endocarditis, cure may be achieved with antifungal therapy alone. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
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140. Seven-year clinical and mechanical follow-up of a Tetralogy of Fallot patient with severe pulmonary regurgitation.
- Author
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Minderhoud, Savine C S, Akyildiz, Ali C, Hirsch, Alexander, and Helbing, Willem A
- Subjects
COMPUTER simulation ,VENTRICULAR ejection fraction ,PULMONARY stenosis ,TETRALOGY of Fallot ,PULMONARY valve diseases ,TREATMENT effectiveness ,MATHEMATICS ,PROSTHETIC heart valves - Published
- 2022
- Full Text
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141. Isolated pulmonary valve endocarditis: truth or myth?
- Author
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Seraj, Siamak M., Gill, Evanpaul, and Sekhon, Simranjit
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PULMONARY stenosis ,PULMONARY valve diseases - Abstract
Pulmonary valve (PV) infective endocarditis (IE) is an extremely rare disease that involves normal as well as abnormal valves. This condition mostly occurs in patients with underlying predisposing factors. It couldbemissedif patients donotpresent with typical features of right-sided endocarditis or in the absence of classic risk factors. The case presented here did not have any known risk factors for IE until surgery and presented mainly with fever, weight loss and musculoskeletal symptoms. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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142. Exacerbation of Pulmonic Regurgitation by Diastolic Tricuspid Regurgitation.
- Author
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Fan, Dali, Makaryus, John N., Wassef, Bishoy, Suma, Valentin, Masry, Mina, and Makaryus, Amgad N.
- Subjects
- *
TRICUSPID valve diseases , *DOPPLER echocardiography , *ELECTRODES , *ARTIFICIAL implants , *MITRAL valve insufficiency , *SYNCOPE , *DIAGNOSIS ,PULMONARY valve diseases - Abstract
Few cases of diastolic mitral regurgitation (MR) and tricuspid regurgitation (TR) have been reported in the world literature. We report the case of a 63-year-old woman admitted for syncope, with a permanent pacemaker following complete heart block. Echocardiography revealed that the timing of the diastolic TR (and noted MR) coincided with the second phase of the pulmonic insufficiency (PI) jet. The respirometer revealed that the diastolic TR and the second phase of the PI are highly sensitive to respiration (attenuated with inspiration and exacerbated with expiration). The uniqueness of this case is the rare occurrence of the exacerbation of PI as the result of diastolic TR. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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- View/download PDF
143. CT and MRI of pulmonary valvular abnormalities.
- Author
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Rajiah, P., Nazarian, J., Vogelius, E., and Gilkeson, R.C.
- Subjects
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COMPUTED tomography , *ECHOCARDIOGRAPHY , *MAGNETIC resonance imaging , *HEART valve diseases , *LUNG diseases , *DIAGNOSIS ,PULMONARY valve diseases - Abstract
Pulmonary valve disease constitutes a wide spectrum of conditions. Traditionally, echocardiography has been the technique of choice for the evaluation of pulmonary and other valvular disease. However, with advances in technology, computed tomography (CT) and magnetic resonance imaging (MRI) are playing increasingly important roles in the evaluation of these disorders. In this article, we review the normal appearance of the pulmonary valve and then illustrate various variants and pathological entities of the pulmonary valve. [Copyright &y& Elsevier]
- Published
- 2014
- Full Text
- View/download PDF
144. Physicochemical characteristics of nanomaterials that affect pulmonary inflammation.
- Author
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Braakhuis, Hedwig M., Park, Margriet V. D. Z., Gosens, Ilse, De Jong, Wim H., and Cassee, Flemming R.
- Subjects
NANOSTRUCTURED materials ,PULMONARY infarction ,INHALATION injuries ,NANOPARTICLES ,PULMONARY valve diseases - Abstract
The increasing manufacture and use of products based on nanotechnology raises concerns for both workers and consumers. Various studies report induction of pulmonary inflammation after inhalation exposure to nanoparticles, which can vary in aspects such as size, shape, charge, crystallinity, chemical composition, and dissolution rate. Each of these aspects can affect their toxicity, although it is largely unknown to what extent. The aim of the current review is to analyse published data on inhalation of nanoparticles to identify and evaluate the contribution of their physicochemical characteristics to the onset and development of pulmonary inflammation. Many physicochemical characteristics of nanoparticles affect their lung deposition, clearance, and pulmonary response that, in combination, ultimately determine whether pulmonary inflammation will occur and to what extent. Lung deposition is mainly determined by the physical properties of the aerosol (size, density, shape, hygroscopicity) in relation to airflow and the anatomy of the respiratory system, whereas clearance and translocation of nanoparticles are mainly determined by their geometry and surface characteristics. Besides size and chemical composition, other physicochemical characteristics influence the induction of pulmonary inflammation after inhalation. As some nanoparticles dissolve, they can release toxic ions that can damage the lung tissue, making dissolution rate an important characteristic that affects lung inflammation. Fibre-shaped materials are more toxic to the lungs compared to spherical shaped nanoparticles of the same chemical composition. In general, cationic nanoparticles are more cytotoxic than neutral or anionic nanoparticles. Finally, surface reactivity correlates well with observed pulmonary inflammation. With all these characteristics affecting different stages of the events leading to pulmonary inflammation, no unifying dose metric could be identified to describe pulmonary inflammation for all nanomaterials, although surface reactivity might be a useful measure. To determine the extent to which the various characteristics influence the induction of pulmonary inflammation, the effect of these characteristics on lung deposition, clearance, and pulmonary response should be systematically evaluated. The results can then be used to facilitate risk assessment by categorizing nanoparticles according to their characteristics. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
145. Infective endocarditis following percutaneous pulmonary valve replacement: Diagnostic challenges and application of intra-cardiac echocardiography.
- Author
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Cheung, Gary, Vejlstrup, Niels, Ihlemann, Nikolaj, Arnous, Samer, Franzen, Olaf, Bundgaard, Henning, and Søndergaard, Lars
- Subjects
- *
ENDOCARDITIS , *PULMONARY valve , *ECHOCARDIOGRAPHY , *RETROSPECTIVE studies , *FOLLOW-up studies (Medicine) , *PATIENTS , *DIAGNOSIS , *SURGERY ,PULMONARY valve diseases - Abstract
Abstract: Background: Infective endocarditis (IE) following percutaneous pulmonary valve replacement (PPVR) with the Melody valve is rarely reported. Furthermore, there are challenges in this diagnosis; especially echocardiographic evidence of vegetation within the prosthesis may be difficult. Method and result: This study is a retrospective review of all patients with Melody valve implantation in a tertiary centre. Between November 2006 and November 2012, 43 procedures were performed in 42 patients (mean age 25years, 6–67years). At a median follow-up of 27months (2–66months), six patients were suspected for IE. However, repeated transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE) showed no evidence of IE and the patients were diagnosed as possible cases according to the modified Duke's criteria. Two patients did not respond to antibiotic treatment and underwent intra-cardiac echocardiography (ICE), which clearly demonstrated vegetations. These two cases required surgical explantation, while the other four patients were treated medically without complications. Conclusion: IE after Melody valve implantation is uncommon, but difficult to verify since TTE and TEE often cannot demonstrate vegetations inside the stent. ICE should be considered in suspected cases of IE following PPVR with negative TTE and TEE examinations in order to early tailor the best treatment for the individual patient suspected for IE. [Copyright &y& Elsevier]
- Published
- 2013
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146. Quadricuspid pulmonic valve and great pulmonary artery aneurysm by multimodality imaging.
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Ziming Zhang, Yuman Li, Bin Wang, Li Zhang, and Mingxing Xie
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- *
PULMONARY artery , *PULMONARY valve , *COMPUTED tomography , *ANEURYSMS ,PULMONARY valve diseases - Abstract
The article presents a case study related to 71-year-old man was admitted to our hospital with chest tightness and progressive dyspnea. Topics include the physical examination has revealed normal left ventricular impulse, and diastolic murmur at the left sternal border, the chest X-ray revealed has enlarged contour of the vessel below the aortopulmonary window, and the aneurysmal dilation of the main pulmonary artery and left pulmonary artery was revealed through transthoracic echocardiography.
- Published
- 2021
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147. Diagnóstico y tratamiento de la estenosis pulmonar valvular en el perro: Esta anomalía congénita no suele dar síntomas en los primeros meses de vida del cachorro. Una vez confirmada mediante pruebas complementarias, en la mayoría de los casos suele requerir tratamiento quirúrgico
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Porteiro Vázquez, María
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PULMONARY valve diseases ,DOG diseases ,ANIMAL nutrition ,SYNCOPE ,VOMITING in animals - Abstract
The article focuses on the diagnosis and treatment of pulmonary valve stenosis in dogs. It mentions that there are multiple causes that can bringdogs to this situation such as processes viral, bacterial and nutritional; and mentions that the causes of fainting may be infectious in origin or not infectious. It mentions that this will not always show up with the classic symptoms of vomiting and diarrhea bloody.
- Published
- 2021
148. Paediatric cardiologists perform breatkthrough cardiac surgery on 17-year-old.
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CARDIAC catheterization ,MINIMALLY invasive procedures ,CARDIOLOGISTS ,PULMONARY valve diseases ,TREATMENT effectiveness ,PEDIATRIC cardiology ,ADOLESCENCE - Abstract
The article presents a case study of a pioneering paediatric cardiac procedure, Percutaneous Transcatheter Pulmonary Valve Implantation (TPVI), performed on a 17-year-old Engineering student Shaik Imran at Apollo Hospitals, Hyderabad. It mentions that TPVI as a minimally invasive procedure performed in the Cath lab through the veins of the groin region via a large bore sheath called the python sheath.
- Published
- 2022
149. Clinical and Electrocardiographic Findings for Predicting the Severity of Pulmonary Valve Stenosis in Dogs.
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Bini, Martina, Vezzosi, Tommaso, Fernández Del Palacio, Maria Josefa, Talavera, Jesús, Patata, Valentina, Marchesotti, Federica, and Domenech, Oriol
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PULMONARY valve diseases ,ELECTROCARDIOGRAPHY ,DOG diseases ,HEART murmurs ,CLINICAL trials - Abstract
Pulmonary valve stenosis (PS) in dogs is usually suspected due to the presence of a heart murmur and clinical signs. Echocardiography is needed to confirm the diagnosis and define the severity of PS. This retrospective study evaluated the utility of clinical and electrocardiographic (ECG) findings in the prediction of PS severity. Data regarding heart murmur and ECG analysis were gathered. Ninety-seven dogs with PS were included. A murmur grade ≥IV/VI was predictive of severe PS (area under curve (AUC) = 0.71; sensitivity (Se) = 95%; specificity (Sp) = 33%; p = 0.003). In lead II, P wave amplitude >0.35 mV (AUC = 0.67; Se = 31%; Sp = 100%; p = 0.038), Q wave < 0.15 mV (AUC = 0.70; Se = 70%; Sp = 59%; p = 0.0015), R wave < 0.87 mV (AUC = 0.66; Se = 67%; Sp = 69%; p = 0.006), and S wave > 0.37 mV (AUC = 0.80; Se = 72%; Sp = 85%; p < 0.0001) were predictive of severe PS. The extent of right deviation of the mean electrical axis of the QRS complex was correlated with the pulmonary pressure gradient (r = 0.648; p < 0.0001). In conclusion, a systolic murmur with intensity ≥IV/VI, a P wave amplitude >0.35 mV, low amplitude of Q and R waves, deep S waves in lead II, and right axis deviation of the QRS complex in a young dog are predictive of severe PS. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
150. Reply to the letter by Dr. Rao: Role of palliative balloon pulmonary valvuloplasty in babies with tetralogy of Fallot.
- Author
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Muneuchi, Jun
- Subjects
- *
TETRALOGY of Fallot , *PERCUTANEOUS balloon valvuloplasty , *CONGENITAL heart disease , *INFANTS , *HEART valve diseases ,PULMONARY valve diseases - Published
- 2020
- Full Text
- View/download PDF
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