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2,181 results on '"Ramos, Daniel"'

103. Programmed Cell Death Modifies Neural Circuits and Tunes Intrinsic Behavior

Author

Kochersberger, Alison, primary, Torkashvand, Mohammad Mahdi, additional, Lee, Dongyeop, additional, Baskoylu, Saba, additional, Sengupta, Titas, additional, Koonce, Noelle, additional, Emerson, Chloe, additional, Patel, Nandan V, additional, Colón-Ramos, Daniel, additional, Flavell, Steven W, additional, Horvitz, H. Robert, additional, Venkatachalam, Vivek, additional, and Hammarlund, Marc, additional

Published
2023
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105. Impact age-adjusted Charlson comorbidity index on hospital and one year mortality in chilean patients with COVID-19

Author

Cayupi, Felipe, primary, Lolas, Miljenko, additional, Arancibia, Francisco, additional, Corrales, María José, additional, Cuevas, Juan Pablo, additional, Ramos, Daniel, additional, Tamblay, Constanza, additional, Ramirez, Karina, additional, Venegas, Janielee, additional, Cheg, Jorge, additional, Gonzalez, Roberto, additional, Chahuan, Elias, additional, and Camp, Carolina, additional

Published
2023
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107. Genomic epidemiology unveils the dynamics and spatial corridor behind the Yellow Fever virus outbreak in Southern Brazil

Author

Giovanetti, Marta, primary, Pinotti, Francesco, additional, Zanluca, Camila, additional, Fonseca, Vagner, additional, Nakase, Taishi, additional, Koishi, Andrea C., additional, Tscha, Marcel, additional, Soares, Guilherme, additional, Dorl, Gisiane Gruber, additional, Marques, Antônio Ernesto M.L, additional, Sousa, Renato, additional, Adelino, Talita Emile Ribeiro, additional, Xavier, Joilson, additional, de Oliveira, Carla, additional, Patroca, Sandro, additional, Guimaraes, Natalia Rocha, additional, Fritsch, Hegger, additional, Mares-Guia, Maria Angélica, additional, Levy, Flavia, additional, Passos, Pedro Henrique, additional, da Silva, Vinicius Leme, additional, Pereira, Luiz Augusto, additional, Mendonça, Ana Flávia, additional, de Macêdo, Isabel Luana, additional, Ribeiro de Sousa, Davi Emanuel, additional, Rodrigues de Toledo Costa, Gabriela, additional, Botelho de Castro, Marcio, additional, de Souza Andrade, Miguel, additional, de Abreu, Filipe Vieira Santos, additional, Campos, Fabrício Souza, additional, Iani, Felipe Campos de Melo, additional, Pereira, Maira Alves, additional, Cavalcante, Karina Ribeiro Leite Jardim, additional, de Freitas, Andre Ricardo Ribas, additional, Campelo de Albuquerque, Carlos Frederico, additional, Macário, Eduardo Marques, additional, dos Anjos, Marlei Pickler Debiasi, additional, Ramos, Rosane Campanher, additional, Campos, Aline Alves Scarpellini, additional, Pinter, Adriano, additional, Chame, Marcia, additional, Abdalla, Livia, additional, Riediger, Irina Nastassja, additional, Ribeiro, Sérvio Pontes, additional, Bento, Ana I., additional, de Oliveira, Tulio, additional, Freitas, Carla, additional, Oliveira de Moura, Noely Fabiana, additional, Fabri, Allison, additional, dos Santos Rodrigues, Cintia Damasceno, additional, Dos Santos, Carolina Cardoso, additional, Barreto de Almeida, Marco Antonio, additional, dos Santos, Edmilson, additional, Cardoso, Jader, additional, Augusto, Douglas Adriano, additional, Krempser, Eduardo, additional, Mucci, Luís Filipe, additional, Gatti, Renata Rispoli, additional, Cardoso, Sabrina Fernandes, additional, Fuck, João Augusto Brancher, additional, Lopes, Maria Goretti David, additional, Belmonte, Ivana Lucia, additional, Mayoral Pedroso da Silva, Gabriela, additional, Soares, Maiane Regina Ferreira, additional, de Castilhos, Marilia de Melo Santos, additional, de Souza e Silva, Joseana Cardoso, additional, Bisetto Junior, Alceu, additional, Pouzato, Emanuelle Gemin, additional, Tanabe, Laurina Setsuko, additional, Arita, Daniele Akemi, additional, Matsuo, Ricardo, additional, dos Santos Raymundo, Josiane, additional, Silva, Paula Cristina Linder, additional, Santana Araújo Ferreira Silva, Ana, additional, Samila, Sandra, additional, Carvalho, Glauco, additional, Stabeli, Rodrigo, additional, Navegantes, Wildo, additional, Moreira, Luciano Andrade, additional, Ferreira, Alvaro Gil A., additional, Pinheiro, Guilherme Garcia, additional, Nunes, Bruno Tardelli Diniz, additional, de Almeida Medeiros, Daniele Barbosa, additional, Cruz, Ana Cecília Ribeiro, additional, Venâncio da Cunha, Rivaldo, additional, Van Voorhis, Wes, additional, Bispo de Filippis, Ana Maria, additional, Almiron, Maria, additional, Holmes, Edward C., additional, Ramos, Daniel Garkauskas, additional, Romano, Alessandro, additional, Lourenço, José, additional, Alcantara, Luiz Carlos Junior, additional, and Duarte dos Santos, Claudia Nunes, additional

Published
2023
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109. Local and dynamic regulation of neuronal glycolysisin vivo

Author

Wolfe, Aaron D., primary, Koberstein, John N, additional, Smith, Chadwick B, additional, Stewart, Melissa L, additional, Hammarlund, Marc, additional, Hyman, Anthony, additional, Stork, Philip JS, additional, Goodman, Richard, additional, and Colón-Ramos, Daniel A., additional

Published
2023
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110. Case report: Urbanized non-human primates as sentinels for human zoonotic diseases: a case of acute fatal toxoplasmosis in a free-ranging marmoset in coinfection with yellow fever virus

Author

Sousa, Davi E. R., primary, Wilson, Tais M., additional, Macêdo, Isabel L., additional, Romano, Alessandro P. M., additional, Ramos, Daniel G., additional, Passos, Pedro H. O., additional, Costa, Gabriela R. T., additional, Fonseca, Vagner S., additional, Mares-Guia, Maria Angélica M. M., additional, Giovanetti, Marta, additional, Alcantara, Luiz Carlos Junior, additional, de Filippis, Ana Maria B., additional, Paludo, Giane R., additional, Melo, Cristiano B., additional, and Castro, Márcio B., additional

Published
2023
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113. ESTÁGIO SUPERVISIONADO EM COMPUTAÇÃO: NO ENSINO FUNDAMENTAL I – A IMPORTÂNCIA DO USO DE RECURSOS TECNOLÓGICOS NAS SALAS DE AULA

Author

Batista, Francisco Rayner Barros, primary, Barbosa, Luiz Sergio de Oliveira, additional, Oliveira, Rogério Brito de, additional, Pinho, Arley Silva de, additional, Silva, Gabriel Natividade da, additional, Mendes, Luis Eduardo Rocha, additional, Ramos, Daniel do Nascimento, additional, and Silva, Eloir Santos da, additional

Published
2023
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115. Nanomechanical resonant structures in single-crystal diamond

Author

Burek, Michael J., Ramos, Daniel, Patel, Parth, Frank, Ian W., and Lončar, Marko

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

With its host of outstanding material properties, single-crystal diamond is an attractive material for nanomechanical systems. Here, the mechanical resonance characteristics of freestanding, single-crystal diamond nanobeams fabricated by an angled-etching methodology are reported. Resonance frequencies displayed evidence of significant compressive stress in doubly clamped diamond nanobeams, while cantilever resonance modes followed the expected inverse-length-squared trend. Q-factors on the order of 104 were recorded in high vacuum. Results presented here represent initial groundwork for future diamond-based nanomechanical systems which may be applied in both classical and quantum applications.

Published
2013
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119. Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment

Author

Ramos, Daniel M., d'Ydewalle, Constantin, Gabbeta, Vijayalakshmi, Dakka, Amal, Klein, Stephanie K., Norris, Daniel A., Matson, John, Taylor, Shannon J., Zaworski, Phillip G., Prior, Thomas W., Snyder, Pamela J., Valdivia, David, Hatem, Christine L., Waters, Ian, Gupte, Nikhil, Swoboda, Kathryn J., Rigo, Frank, Bennett, C. Frank, Naryshkin, Nikolai, Paushkin, Sergey, Crawford, Thomas O., and Sumner, Charlotte J.

Subjects
Thermo Fisher Scientific Inc., Nusinersen, Pregnant women, RNA, Scientific equipment industry, Spinal muscular atrophy, Messenger RNA, Neurons, Muscular atrophy, Brain, Retirement benefits, Health care industry, Johns Hopkins University. School of Medicine
Abstract

BACKGROUND. Spinal muscular atrophy (SMA) is caused by deficient expression of survival motor neuron (SMN) protein. New SMN-enhancing therapeutics are associated with variable clinical benefits. Limited knowledge of baseline and drug-induced SMN levels in disease-relevant tissues hinders efforts to optimize these treatments. METHODS. SMN mRNA and protein levels were quantified in human tissues isolated during expedited autopsies. RESULTS. SMN protein expression varied broadly among prenatal control spinal cord samples, but was restricted at relatively low levels in controls and SMA patients after 3 months of life. A 2.3-fold perinatal decrease in median SMN protein levels was not paralleled by comparable changes in SMN mRNA. In tissues isolated from nusinersen-treated SMA patients, antisense oligonucleotide (ASO) concentration and full-length (exon 7 including) SMN2 (SMN2-FL) mRNA level increases were highest in lumbar and thoracic spinal cord. An increased number of cells showed SMN immunolabeling in spinal cord of treated patients, but was not associated with an increase in whole-tissue SMN protein levels. CONCLUSIONS. A normally occurring perinatal decrease in whole-tissue SMN protein levels supports efforts to initiate SMN-inducing therapies as soon after birth as possible. Limited ASO distribution to rostral spinal and brain regions in some patients likely limits clinical response of motor units in these regions for those patients. These results have important implications for optimizing treatment of SMA patients and warrant further investigations to enhance bioavailability of intrathecally administered ASOs. FUNDING. SMA Foundation, SMART, NIH (R01-NS096770, R01-NS062869), Ionis Pharmaceuticals, and PTC Therapeutics. Biogen provided support for absolute real-time RT-PCR., Introduction The neuromuscular disease spinal muscular atrophy (SMA), affecting approximately 1 in 10,000 individuals, is the most common inherited cause of infant death (1). The most frequent and severe type [...]

Published
2019
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121. Pituitary dysfunction in granulomatosis with polyangiitis

Author

Vega-Beyhart, Arturo, Medina-Rangel, Irene Rocío, Hinojosa-Azaola, Andrea, Fernández-Barrio, Milagros, Vargas-Castro, Ana Sofía, García-Inciarte, Lucía, Guzmán-Pérez, Alberto, Torres-Victoria, Tania Raisha, Martínez-Sánchez, Froylán David, Pérez-Guzmán, Mireya Citlali, Hinojosa-Amaya, José Miguel, León-Suárez, Andrés, Gómez-Sámano, Miguel Angel, Gómez-Pérez, Francisco Javier, and Cuevas-Ramos, Daniel

Published
2020
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126. Gradient Ricci solitons on surfaces

Author

Ramos, Daniel

Subjects
Mathematics - Differential Geometry
Abstract

We classify and expose all the gradient Ricci solitons on complete surfaces, open or closed, with curvature bounded below, and possibly with a discrete set of cone-like singular points that arise naturally. We give a precise qualitative description of each metric in terms of a phase portrait, that is the most accurate description for all cases that do not admit an explicit expression in terms of elementary functions. Our classification contains examples of smooth and conic solitons that were not described in the classic literature. We add some visual embeddings in R^3 for aesthetics., Comment: 23 pages, 13 figures

Published
2013

127. An asymptotically cusped three dimensional expanding gradient Ricci soliton

Author

Ramos, Daniel

Subjects
Mathematics - Differential Geometry
Abstract

We construct an expanding gradient Ricci soliton in dimension three over the topological manifold R x T^2 (the product of a line and a torus) that aproaches asymptotically a constant curvature cusp at one end, and a flat manifold on the other end. We prove that this is the only gradient soliton with this topology, provided the curvature is negatively pinched, -1/4 < sec < 0, at the time-zero manifold (normalizing the soliton to be born at time -1)., Comment: 19 pages, 5 figures. Corrected sentence on page 3

Published
2012

128. Smoothening cone points with Ricci flow

Author

Ramos, Daniel

Subjects
Mathematics - Differential Geometry
Abstract

We consider Ricci flow on a closed surface with cone points. The main result is: given a (nonsmooth) cone metric g_0 over a closed surface there is a smooth Ricci flow g(t) defined for (0,T], with curvature unbounded above, such that g(t) tends to g_0 as t tends to 0. This result means that Ricci flow provides a way for instantaneously smoothening cone points. We follow an argument of P. Topping modifying his reasoning for cusps of negative curvature; in that sense we can consider cusps as a limiting zero-angle cone, and we generalize to any angle between 0 and 2\pi.

Published
2011

129. Wnt Signaling Regulates Pulp Volume and Dentin Thickness

Author

Lim, Won Hee, Liu, Bo, Cheng, Du, Hunter, Daniel J, Zhong, Zhendong, Ramos, Daniel M, Williams, Bart O, Sharpe, Paul T, Bardet, Claire, Mah, Su‐jung, and Helms, Jill A

Subjects
Biomedical and Clinical Sciences, Dentistry, Dental/Oral and Craniofacial Disease, Animals, Core Binding Factor Alpha 1 Subunit, Dental Pulp, Dentin, Mice, Real-Time Polymerase Chain Reaction, Signal Transduction, Wnt Proteins, DENTIN, ODONTOBLAST, PULP, WNT SIGNALING PATHWAY, Biological Sciences, Engineering, Medical and Health Sciences, Anatomy & Morphology, Biological sciences, Biomedical and clinical sciences
Abstract

Odontoblasts, cementoblasts, ameloblasts, and osteoblasts all form mineralized tissues in the craniofacial complex, and all these cell types exhibit active Wnt signaling during postnatal life. We set out to understand the functions of this Wnt signaling, by evaluating the phenotypes of mice in which the essential Wnt chaperone protein, Wntless was eliminated. The deletion of Wls was restricted to cells expressing Osteocalcin (OCN), which in addition to osteoblasts includes odontoblasts, cementoblasts, and ameloblasts. Dentin, cementum, enamel, and bone all formed in OCN-Cre;Wls(fl/fl) mice but their homeostasis was dramatically affected. The most notable feature was a significant increase in dentin volume and density. We attribute this gain in dentin volume to a Wnt-mediated misregulation of Runx2. Normally, Wnt signaling stimulates Runx2, which in turn inhibits dentin sialoprotein (DSP); this inhibition must be relieved for odontoblasts to differentiate. In OCN-Cre;Wls(fl/fl) mice, Wnt pathway activation is reduced and Runx2 levels decline. The Runx2-mediated repression of DSP is relieved and odontoblast differentiation is accordingly enhanced. This study demonstrates the importance of Wnt signaling in the homeostasis of mineralized tissues of the craniofacial complex.

Published
2014

134. Impact of lymph node ratio and number of lymph node metastases on survival and recurrence in laryngeal squamous cell carcinoma

Author

Molteni, Gabriele, primary, Nocini, Riccardo, additional, Mattioli, Francesco, additional, Nakayama, Meijin, additional, Dedivitis, Rogerio A., additional, Mannelli, Giuditta, additional, Crosetti, Erika, additional, Chiesa‐Estomba, Carlos Miguel, additional, Sistiaga‐Suarez, Jon A., additional, Giordano, Leone, additional, Galli, Andrea, additional, Lionello, Marco, additional, Mercante, Giuseppe, additional, Ralli, Massimo, additional, Fermi, Matteo, additional, Klein‐Rodríguez, Alejandro, additional, Mayo‐Yáñez, Miguel, additional, Serafini, Edoardo, additional, Pirola, Francesca, additional, Paderno, Alberto, additional, Cambria, Francesca, additional, Oridate, Nobuhiko, additional, Sano, Daisuke, additional, Boscolo‐Rizzo, Paolo, additional, Marcuzzo, Alberto Vito, additional, Parrinello, Giampiero, additional, Marchi, Filippo, additional, Saibene, Alberto Maria, additional, Tucciarone, Manuel, additional, Viscasillas, Guillem, additional, Zeleník, Karol, additional, Ramos, Daniel Marin, additional, Palacios‐Garcia, Jose, additional, Tirelli, Giancarlo, additional, Pellini, Raul, additional, Paludetti, Gaetano, additional, Galli, Jacopo, additional, Rossi, Giorgia, additional, De Vincentiis, Marco, additional, Cernea, Claudio Roberto, additional, Spriano, Giuseppe, additional, Bussi, Mario, additional, Peretti, Giorgio, additional, Succo, Giovanni, additional, Piazza, Cesare, additional, Bertolin, Andy, additional, Kowalski, Luiz Paulo, additional, Presutti, Livio, additional, and Sacchetto, Andrea, additional

Published
2023
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135. Prolactinoma e hiperprolactinemia. Posicionamiento de la SMNE

Author

Sosa-Eroza, Ernesto, primary, Cuevas-Ramos, Daniel, additional, Domínguez, Benito, additional, Espinosa-Cárdenas, Etual, additional, Hinojosa-Amaya, José M., additional, Martínez-Cruz, Nayeli, additional, Mendoza-Zubieta, Victoria, additional, Mercado-Atri, Moises, additional, Ramírez-Rentería, Claudia, additional, Rangel, Gabriela, additional, Rivera-Hernández, Aleida de Jesús, additional, and Vidrio-Velázquez, Maricela, additional

Published
2023
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136. Posición del Grupo de Trabajo de Neuroendocrinología respecto a los adenomas de hipófisis no funcionantes

Author

Vargas-Ortega, Guadalupe, primary, Abreu-Rosario, Coralys, additional, Balcázar-Hernández, Lourdes, additional, Balderrama-Soto, Adriana, additional, Carrillo-González, Perla A., additional, Cuevas-Ramos, Daniel, additional, González-Virla, Baldomero, additional, Rangel, Gabriela, additional, Reza-Albarrán, Alfredo A., additional, Vergara-López, Alma, additional, Vidrio-Velázquez, Maricela, additional, Portocarrero-Ortiz, Lesly, additional, and Mercado-Atri, Moises, additional

Published
2023
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137. Diagnóstico y tratamiento de la enfermedad de Cushing. Actualidades y posicionamiento del Grupo de Trabajo de Neuroendocrinología de la Sociedad Mexicana de Nutrición y Endocrinología

Author

Espinosa de los Monteros-Sánchez, Ana L., primary, Cuevas-Ramos, Daniel, additional, Espinosa-Cárdenas, Etual, additional, Hinojosa-Amaya, José M., additional, Reza-Albarrán, Alfredo A., additional, Navas-Minero, Carmen E., additional, Balderrama-Soto, Adriana, additional, Rangel, Gabriela, additional, Vergara-López, Alma, additional, Abreu-Rosario, Coralys, additional, Rivera-Hernández, Aleida, additional, Valdivia-López, Jorge A., additional, Portocarrero-Ortiz, Lesly, additional, Nava-De la Vega, Alfredo, additional, Carrillo-González, Perla A., additional, and Mercado-Atri, Moises, additional

Published
2023
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139. The Importance of Entomo-Virological Investigation of Yellow Fever Virus to Strengthen Surveillance in Brazil

Author

Cruz, Ana Cecília Ribeiro, primary, Hernández, Leonardo Henrique Almeida, additional, Aragão, Carine Fortes, additional, da Paz, Thito Yan Bezerra, additional, da Silva, Sandro Patroca, additional, da Silva, Fábio Silva, additional, de Aquino, Ana Alice, additional, Cereja, Glennda Juscely Galvão Pereira, additional, Nascimento, Bruna Lais Sena do, additional, Rosa Junior, José Wilson, additional, Elias, Carmeci Natalina, additional, Nogueira, Cristiano Gomes, additional, Ramos, Daniel Garkauskas, additional, Fonseca, Vagner, additional, Giovanetti, Marta, additional, Alcantara, Luiz Carlos Junior, additional, Nunes, Bruno Tardelli Diniz, additional, Vasconcelos, Pedro F. da Costa, additional, Martins, Livia Carício, additional, and Nunes-Neto, Joaquim Pinto, additional

Published
2023
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142. Supporting diversity in science through social networking.

Author

Guerrero-Medina, Giovanna, Feliú-Mójer, Mónica, González-Espada, Wilson, Díaz-Muñoz, Greetchen, López, Marcos, Díaz-Muñoz, Samuel L, Fortis-Santiago, Yaihara, Flores-Otero, Jacqueline, Craig, David, and Colón-Ramos, Daniel A

Subjects
Humans, Communication, Science, Research, Cultural Diversity, Societies, Scientific, Puerto Rico, Social Networking, Workforce, Developmental Biology, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences
Published
2013

147. WHEN GI JOE SAW RED: Nazi-hating Sergeant Joe Beyrle served in both the U.S. Army and Soviet Red Army during World War II

Author

Ramos, Daniel

Subjects
United States. Army, Infantry -- Military aspects, Paratroops -- Military aspects, Aircraft, Soldiers, Footbridges, History, Military and naval science
Abstract

Waves of C-47 Skytrains in formation flew east across the English Channel toward Normandy under cover of darkness, an overcast sky eclipsing the stars and moon above. In one plane [...]

Published
2019

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