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PubMedID: 26406185 BACKGROUND: Patients with spinal cord injury (SCI) and hemiplegia are at risk of fractures partly due to decreased bone mineral density with relation to the low levels of vitamin D. OBJECTIVE: The objective of this study is to evaluate the vitamin D profile of patients with SCI and post-stroke hemiplegia. METHODS: 25(OH)D levels of patients with SCI and hemiplegia were obtained from the electronic medical record database and compared with age- and sex-matched non-disabled controls. Furthermore, the effect of Functional Ambulation Category (FAC), American Spinal Injury Association (ASIA) level and Brunnstrom's recovery stage, on vitamin D insufficiency, was studied. RESULTS: The study sample consisted of 173 individuals (118 patients and 55 controls). Vitamin D levels and sufficiency rates of the neurologically disabled patients was significantly lower than that of controls (p = 0.000 and p = 0.000, respectively). However, there was no difference between patients with SCI and hemiplegia regarding the 25(OH)D levels and vitamin D insufficiency (p = 0.303 and p = 0.952, respectively). There were no statistically significant differences in vitamin D status by American Spinal Injury Association (ASIA) level and Brunnstrom's score. However, regression analysis revealed that vitamin D insufficiency rate of non-functionally ambulatory (FAC = 0-2) patients was higher than that of functionally ambulatory (FAC = 3-5) ones (p = 0.044). CONCLUSIONS: Vitamin D status of patients with neurological disabilities was lower than that of controls. Non-functionally ambulatory patients had higher vitamin D insufficiency rate than functionally ambulatory patients. Preventative measures including adequate supplementation of vitamin D should be directed to neurologically disabled subjects, particularly those with non-functional ambulation. © 2016 - IOS Press and the authors. All rights reserved.

Resilience is an emerging concept for analyzing the dynamic performance of critical infrastructures during the post-disaster recovery process. Although a number of studies examined how to assess long-term resilience (1 year +), very few have investigated short-term resilience (few days to several weeks following a disaster). This study presents the new concept of ‘emergency resilience’ and the framework for assessing this short-term resilience for urban lifeline systems in the emergency recovery stage. This framework can quantify differences in system performance (pre-disaster vs. post-recovery) using the new ‘recovery degree’ feature. It also integrates a new performance response function which is based on network equilibrium theory to assess emergency resilience in both the technical and organisational dimensions. In the case study of the water pipeline network in Lianyungang, China, the results showed that the levels of the recovery budget b and recovery resource r had different effects on emer...

The red alga Pyropia yezoensis is traditionally cultivated in Japan, and the surplus production that is not consumed is utilized in other ways. Because this alga contains highly concentrated protein, we investigated the dietary effects of fresh P. yezoensis on the gonadal production and quality of the adult sea urchin Mesocentrotus nudus compared with urchins fed the kelp Saccharina ochotensis, in a 60-day rearing experiment from April to June 2009. The digestibility of P. yezoensis by the sea urchins was 96.2%. The gonads were in the recovery stage at the start and end of feeding. The gonad index of the sea urchins fed P. yezoensis was 20.8, significantly higher than that of the urchins fed S. ochotensis. When the urchins were fed P. yezoensis, the proportion of bright reddish-yellow gonads increased markedly, to 50% in the testes and 90.9% in the ovaries. The content of the sweet amino acid, glycine, in the gonads of urchins fed P. yezoensis was significantly lower than at the start of feeding, and the contents of the bitter amino acids, lysine and valine, were significantly higher in the ovaries than in urchins fed S. ochotensis or at the start of feeding. Despite the increase in gonad production and the improvement in gonad color after the consumption of P. yezoensis, these changes in amino acids indicate a reduction in the quality of the gonad as food. The crude protein content of P. yezoensis used in this study was 36.7%, which would reduce gonadal quality. We infer that the use of low-protein P. yezoensis, which is discolored and unfit for market, can improve the quality of the urchin gonad.

Purpose The objective of this scoping review was to identify and describe the international scientific literature and published post-disaster needs assessments (PDNAs), on post-disaster provision of healthcare services for sexual and reproductive health. Methodology A systematic search was conducted to identify potential source documents, which were screened for edibility and included documents were full-text reviewed. Thirteen published research papers and 55 PDNAs were reviewed. Results PDNAs did not address the sexual health needs of affected communities in a thorough manner and provided limited guidance on the actions required during the recovery stage. HIV was more likely to be considered in PDNAs than sexually transmitted infections (STI). Source documents showed STI prevalence increased in a community after a disaster, that people living with HIV are particularly vulnerable, and that service provision is influenced by humanitarian agencies’ ability to collaborate across sectors and governments. Conclusion In this first scoping review on the topic, the evidence has shown that there is an enduring gap between the recommendations in published guidelines and the implementation of these during a disaster or crisis. More work is required, as well as critical analysis of post-disaster recovery operations, to identify ways to improve service provision during disaster and crisis settings. In contrast to international humanitarian communities during emergencies, unfortunately, affected governments’ recovery agencies and their donors need to ensure that STI and HIV issues can be systematically identified and addressed during recovery assessment and implementation.

Background: Stroke survivors are accompanied by dysfunctions, greatly declining their activities of daily living and bringing burden to families and societies. Although modern rehabilitation therapy has a systematic program in post-stroke motor rehabilitation, numbers of patients still recover slowly. Eye-acupuncture (EA), as an important type of acupuncture, has been widely applied effectively in rehabilitation of stroke for about 50 years. So we combine EA with modern rehabilitation which has achieved successful results. Therefore, we need to adopt an objective and accurate evaluation method to study the effect of this method. Methods: We aim to design a multi-center, block randomized, parallel control trial to assess the effect of eye-acupuncture combined with rehabilitation training therapy for patients with hemiplegia in the convalescent stage of stroke. 360 patients will be enrolled from 6 centres, with half of them (n = 180) in the control group (routine treatment group) and others (n = 180) in the experimental group (eye-acupuncture combined with routine treatment group). Stratified block randomization will be used in the study and the serial number 001-360 which corresponds to a participant will be assigned to each center randomly. We will use the sequentially sealed envelopes to hide the generating of assignment sequence. The cases of dropouts will be recorded with reasons. And the clinical CRFs will be filled in accurately, completely, and timely for statistical analysis. Results: To verify the clinical effects, we will measure the change of bellows from visit 1 to visit 4. Primary outcomes: activity of daily living (ADL) scales (modified Barthel index); simple Fugl–Meyer motor function score; functional magnetic resonance imaging (fMRI) of the brain in the resting state. Secondary outcomes: traditional Chinese medicine (TCM) syndrome score scale; western aphasia battery (WAB); water swallow test; Montreal cognitive assessment (MoCA); growth-associated protein-43 (GAP-43); microtubule-associated protein-2 (MAP-2). Conclusion: The results of this study will provide present evidence on assessing effectiveness of EA combined with rehabilitation training for patients with hemiplegia in the convalescent stage of stroke. Trial registration: This trial has been registrated in Chinese Clinical Trail Registry with the registration number as ChiCTR1900027835 (http://www.chictr.org.cn/).

Modular multilevel converter (MMC) is widely used in VSC-HVDC. And FRT (fault ride through) is one of the most important issues. In order to simulate the MMC-HVDC fault ride-through characteristics more accurately, this paper focuses on the detailed simulation models, and a probability Thevenin’s equivalent model of MMC is proposed. This paper also proposes a modeling framework that can support three processes: normal state, FRT, and fault recovery stage. The possibility MMC model and control strategies are realized based on an actual VSC-HVDC project in PSModel software. By comparing with the PACAD model provided by the actual manufacturer, the efficacy of the model and control strategy is verified.

The purpose of this study was to investigate the effect of recumbent cycling with integrated volitional control electrical stimulation (IVES) on gait ability in stroke patients. Six stroke patients (all male; average age, 55.7±8.3 years) participated. Recumbent cycling (R-cycling) was performed with and without IVES in the power assist (IVES-P) mode. The targeted muscle for electrostimulation was the tibialis anterior. Patients performed 10 min of IVES-P mode plus R-cycling (program A) or R-cycling alone (program B), once per day, 5 times per week. Patients completed two sets of each program, alternating between programs each week. Gait speed and the number of steps numbers on a 10-m walking test was assessed before and after each interventional session. Program A improved gait speed, but not the number of steps, to a greater extent than that in program B. Specifically, the combined intervention significantly improved gait speed in the first set, but not the second set of the intervention. R-cycling with IVES-P mode improved gait speed during the recovery stage in stroke patients to a greater extent than that achieved with R-cycling alone. Thus, this combined therapy has potential as a standardized treatment in the field of rehabilitation medicine.

This study investigates the potential of enhancing oil recovery from a Middle East heavy oil field via hot water injection followed by injection of a chemical surfactant and/or a biosurfactant produced by a Bacillus subtilis strain which was isolated from oil-contaminated soil. The results reveal that the biosurfactant and the chemical surfactant reduced the residual oil saturation after a hot water flood. Moreover, it was found that the performance of the biosurfactant increased by mixing it with the chemical surfactant. It is expected that the structure of the biosurfactant used in this study was changed when mixed with the chemical surfactant as a probable synergetic effect of biosurfactant-chemical surfactants was observed on enhancing oil recovery, when used as a mixture, rather than alone. This work proved that it is more feasible to inject the biosurfactant as a blend with the chemical surfactant, at the tertiary recovery stage. This might be attributed to the fact that in the secondary mode, improvement of the macroscopic sweep efficiency is important, whereas in the tertiary recovery mode, the microscopic sweep efficiency matters mainly and it is improved by the biosurfactant-chemical surfactant mixture. Also as evidenced by this study, the biosurfactant worked better than the chemical surfactant in reducing the residual heavy oil saturation after a hot water flood.

Purpose – The purpose of this paper is to establish a peridynamic method in predicting viscoelastic creep behaviour with recovery stage and to find the suitable numerical parameters of peridynamic method. Design/methodology/approach – A rheological viscoelastic creep constitutive equation including recovery and an elastic peridynamic equation (with integral basis) are examined and used. The elasticity equation within the peridynamic equation is replaced by the viscoelastic equation. A new peridynamic method with two time parameters, i.e. numerical time and viscoelastic real time is designed. The two parameters of peridynamic method, horizon radius and number of nodes per unit volume are studied to get their optimal values. In validating this peridynamic method, comparisons are made between numerical and analytical result and between numerical and experimental data. Findings – The new peridynamic method for viscoelastic creep behaviour is approved by the good matching in numerical-analytical data comparison with difference of < 0.1 per cent and in numerical-experimental data comparison with difference of 4-6 per cent. It can be used for further creep test which may include non-linear viscoelastic behaviour and creep rupture. From this paper, the variation of constants in Burger’s viscoelastic model is also studied and groups of constants values that can simulate solid, fluid and solid-fluid viscoelastic behaviours were obtained. In addition, the numerical peridynamic parameters were also manipulated and examined to achieve the optimal values of the parameters. Research limitations/implications – The peridynamic model of viscoelastic creep behaviour preferably should have only one time parameter. This can only be done by solving the unstable fluctuation of dynamic results, which is not discussed in this paper. Another limitation is the tertiary region and creep rupture are not included in this paper. Practical implications – The viscoelastic peridynamic model in this paper can serve as an alternative for conventional numerical simulations in viscoelastic area. This model also is the initial step of developing peridynamic model of viscoelastic creep rupture properties (crack initiation, crack propagation, crack branching, etc.), where this future model has high potential in predicting failure behaviours of any components, tools or structures, and hence increase safety and reduce loss. Originality/value – The application of viscoelastic creep constitutive model on peridynamic formulation, effect of peridynamic parameters manipulation on numerical result, and optimization of constants of viscoelastic model in simulating three types of viscoelastic creep behaviours.

The study of recrystallization texture of a cold deformed Fe–Mn–Al–Si–C alloy, with about 30% Mn, has been discussed in this paper. The alloy is fully austenitic at room temperature, and therefore, principal FCC rolling textures were developed in this material at different stages of cold rolling. The present study was undertaken to observe the transformation of FCC rolling texture during recrystallization of a heavily cold deformed specimen. It was observed that isothermal annealing at 750 °C led to a weak recrystallisation texture, which was quite similar to the deformation texture developed at the early stage of cold rolling. During recovery stage, a strong Bs/Goss-type texture was developed, which was identified as a new observation in this work.

The physical processes responsible for a variety of early VLF scattering events have not yet been satisfactorily identified. Properly categorizing the early VLF event type is imperative to understand the causative physical processes involved. In this paper, the onset durations of 26 exceptionally high signal-to-noise ratio early VLF scattering events are analyzed, using scattered fields to classify events. New observations of events that exhibit “slow” amplitude changes, but “fast” scattered field changes are presented, which call into question previous analyses of early/slow events. We separately identify and analyze three early VLF events that definitively exhibit slow scattered field behavior. Additionally, we identify a significant number of events which have onset durations between the current definitions of fast and slow. Four events are observed which unambiguously exhibit a rapid initial rotation of the scattered field phasor during the first few seconds of the recovery stage. Possible physical mechanisms are discussed.

Objective: To examine the fluctuations in body temperature in dogs undergoing routine neutering both during surgery and in the recovery phase. Methods: Utilising a convenience sampling approach, body temperatures of 17 healthy male and female dogs undergoing routine neutering were monitored during and after anaesthesia. Temperature recording was carried out with an auricular thermometer to minimise stress and discomfort. Data analysis was carried out using Microsoft Excel 2013 and Minitab 15. Results: Body temperature of 15 of the 17 dogs dropped below 37°C at some point during or after anaesthesia. Examination of median temperature results revealed a drop from the time of preparation for surgery, through to the time of discharge up to 6 hours after the end of general anaesthesia. At discharge the body temperature of five dogs was still lower than 37°C. Body temperature did not return to preanaesthesia levels during the recovery stage for 16 of the 17 patients. Conclusion: Following anaesthesia dogs are likely to demonstrate a lower than normal body temperature and should therefore be monitored throughout recovery. Longer hospitalisation may be required to ensure patients are only discharged once their temperature has returned to baseline level.

In order to determine the difference in metabolic-energy potential in U16 football players (cadet age) at different levels of competition, a survey was conducted on a sample of sixty players aged 14 to 16. The sample of respondents is divided into the following subsamples: players of Serbian national football team (n=20), players from high-quality league of Vojvodina (n=21) and the players from the regional competition levels (n=19). The lactate blood level was determined by testing capillary blood from the finger during three stages of Cooper test: the concentration of lactate in the standstill stage was measured before the start of the test – before the load; the concentration of lactate during the load stage was measured one minute after completion of the test; and the concentration of lactate in the recovery stage was measured in the tenth minute of recovery. The survey results indicate a statistically significant difference between the said groups of players in relation to the analyzed metabolic-energy parameters of the players.

Vesterinen, V, Nummela, A, Laine, T, Hynynen, E, Mikkola, J, and Häkkinen, K. A submaximal running test with postexercise cardiac autonomic and neuromuscular function in monitoring endurance training adaptation. J Strength Cond Res 31(1): 233-243, 2017-The aim of this study was to investigate whether a submaximal running test (SRT) with postexercise heart rate recovery (HRR), heart rate variability (HRV), and countermovement jump (CMJ) measurements could be used to monitor endurance training adaptation. Thirty-five endurance-trained men and women completed an 18-week endurance training. Maximal endurance performance and maximal oxygen uptake were measured every 8 weeks. In addition, SRTs with postexercise HRR, HRV, and CMJ measurements were carried out every 4 weeks. Submaximal running test consisted of two 6-minute stages at 70 and 80% of maximum heart rate (HRmax) and a 3-minute stage at 90% HRmax, followed by a 2-minute recovery stage for measuring postexercise HRR, HRV, and CMJ test. The highest responders according to the change of maximal endurance performance showed a significant improvement in running speeds during stages 2 and 3 in SRT, whereas no changes were observed in the lowest responders. The strongest correlation was found between the change of maximal endurance performance and running speed during stage 3, whereas no significant relationships were found between the change of maximal endurance performance and the changes of postexercise HRR, HRV, and CMJ. Running speed at 90% HRmax intensity was the most sensitive variable to monitor adaptation to endurance training. The present submaximal test showed potential to monitor endurance training adaptation. Furthermore, it may serve as a practical tool for athletes and coaches to evaluate weekly the effectiveness of training program without interfering in the normal training habits.

Aqueous two-phase systems (ATPS) have been studied and used for product recovery and purification from diverse biological sources. ATPS are characterized by their versatility, easy scale-up parameters, process integration capability, and relative low cost. This technique is commonly regarded as a primary recovery stage mainly due to its low selectivity. However, the use of strategies involving the modification of ATPS with affinity ligands has resulted in significant increases in recovery yields and purification folds of biological products. The aim of this chapter is to highlight current applications, trends, and challenges regarding affinity partitioning in aqueous two-phase systems for the fractionation, recovery, and purification of biological products.

The Sichuan Earthquake (also better known as The Great Wenchuan Earthquake) killed 87,148 and injured 374,643 people. Nurses were mobilized to help in the hospitals and temporary medical tents in the initial triage, controlling infection, providing psychological support, treating complications, and helping patients to start bedside rehabilitation in the recovery stage so that functional capacity and independence could be maximized. Nurses were generally inadequately prepared for this earthquake, but just-in-time training programs, general guidelines and the nurses’ willingness to help made a big difference in helping save lives of individuals and communities.

Stroke is a major public health concern. The lack of effective therapies heightens the need for new therapeutic targets. Mammalian brain has the ability to rewire itself to restore lost functionalities. Promoting regenerative repair, including neurogenesis and dendritic remodeling, may offer a new therapeutic strategy for the treatment of stroke. Here, we report that interaction of neuronal nitric oxide synthase (nNOS) with the protein postsynaptic density-95 (PSD-95) negatively controls regenerative repair after stroke in rats. Dissociating nNOS–PSD-95 coupling in neurons promotes neuronal differentiation of neural stem cells (NSCs), facilitates the migration of newborn cells into the injured area, and enhances neurite growth of newborn neurons and dendritic spine formation of mature neurons in the ischemic brain of rats. More importantly, blocking nNOS–PSD-95 binding during the recovery stage improves stroke outcome via the promotion of regenerative repair in rats. Histone deacetylase 2 in NSCs may mediate the role of nNOS–PSD-95 association. Thus, nNOS–PSD-95 can serve as a target for regenerative repair after stroke.

Schedule disruptions are commonplace in the airline industry with many flight-delaying events occurring each day. Recently there has been a focus on introducing robustness into airline planning stages to reduce the effect of these disruptions. We propose a recoverable robustness technique as an alternative to robust optimisation to reduce the effect of disruptions and the cost of recovery. We formulate the recoverable robust tail assignment problem (RRTAP) as a stochastic program, solved using column generation in the master and subproblems of the Benders' decomposition. We implement a two-phase algorithm for the Benders' decomposition and identify pareto-optimal cuts. The RRTAP includes costs due to flight delays, cancellation, and passenger rerouting, and the recovery stage includes cancellation, delay, and swapping options. To highlight the benefits of simultaneously solving planning and recovery problems in the RRTAP we compare our tail assignment solution against current approaches from the literature. Using airline data we demonstrate that by developing a better tail assignment plan via the RRTAP framework, one can reduce recovery costs in the event of a disruption.

In this study, the objectives are to provide rural experience tourism village business courses and development direction in between individual farmers and the village in base on rural development business of Hapjeon-village. The developmental process of a farm-stay village can be categorized into the period of six stages: 1) a conception stage 2) an adoption stage 3) a growth stage 4) an expansion stage 5) a stagnation stage 6) a recovery stage. Farm Stay Villages, Individual Farmhouses or Producer Groups can be placed in four different quadrant areas of a graph, depending on the pursuing direction and results of core values by having the X-axis for economic factors (public profits, individual profits) and by having the Y-axis for emotional factors (self-actualization, conflicts). The first quadrant area is designated for ideal individual farmhouses and producer groups for having achieved the status of economic self-reliant and high emotional satisfaction. The second quadrant is for ideal self-actualized communal villages having achieved the independent public interest and public profitable status. The third quadrant is reserved for villages experiencing communal conflicts and no economic self-reliant stagnant status. The fourth guardant area is allocated for individual farmhouses and producer groups having achieved self-reliant economic status, yet having communal conflicts. Using the aforementioned concept, the government shall design village development projects and prepare realistic and achievable goals and place them in as a systematic device in future projects.

The effects of shoulder pain and the outcomes of treatments for shoulder pain are of great consequence to the person with tetraplegia, as the shoulder is one of the few functioning regions following spinal cord injury. Shoulder pain is common in tetraplegia. Following cervical spinal cord injury many people experience severe shoulder pain and stiffness, which although frequently seen, is poorly understood. People with long-standing cervical spinal cord injury may experience shoulder pain due to a wide range of pathologies that may relate to overuse or overload of the shoulder. Clinical examination and investigation of the tetraplegic shoulder are similar to evaluation and investigation of the shoulder in ambulant patients. It is also important to consider other factors in the assessment of the tetraplegic shoulder, including wheelchair type, ergonomics and environment. Individual factors include transferring technique, patterns of use and posture, patterns of weakness and stiffness. Treatments commonly include physiotherapy, modifications in environmental factors, sometimes injections and occasionally surgery. If surgery is undertaken, it is important to plan for a period of increased dependence during the recovery stage and optimal to have the support of a spinal injuries rehabilitation unit.

The prevalence of youth depression in Malaysia has increased over the years. This study aims to investigate the experience of teenage depression. In-depth interviews were conducted with university students who were diagnosed with depression in their teens but were in a recovery stage. An in-depth thematic approach was used for data analysis. The paper presents two case studies and reveals some depression narratives in which the participants asked ontological questions about the meaning of their existence. The themes that emerged from the teenagers' depression narratives are in concordance with Martin Heidegger's ontological perspective of "What it means to be in the world". Findings reveal the themes of "Being thrown into the world", "care" and temporality, thus provide insights for parents and educators to better understand the society and culture in which the teens are embedded.

Rationale:H7N9 infection causes acute respiratory distress syndrome with high mortality. The use of glucocorticoids in the acute phase lessened inflammatory responses. Some case reports suggested that secondary organizing pneumonia (SOP) could occur at the recovery stage of the influenza vir

Diet has long been considered a risk factor related to an increased risk of cancer. This challenges us to understand the relationship between the immune system and diet when abnormal cells appear in a tissue. In this paper, we propose and analyze a model from the point of view of a person who follows a healthy diet, i.e., one correlated to the food pyramid, and a person who follows an unhealthy diet. Normal cells and immune cells are used in the design of the model, which aims to describe how the immune system functions when abnormal cells appear in a tissue. The results show that the immune system is able to inhibit and eliminate abnormal cells through the three following stages: the response stage, the interaction stage, and the recovery stage. Specifically, the failure of the immune system to accomplish the interaction stage occurs when a person follows an unhealthy diet. According to the analysis and simulation of our model, we can deduce that dietary pattern has a significant impact on the functioning of the immune system.

[Purpose] This study determined the effects of kinesiology taping on the upper-extremity function and activities of daily living of patients with hemiplegia. [Subjects] The experimental group and control group comprised 15 hemiplegia patients each. [Methods] This study was performed from June 4 to December 22, 2012, involving 30 hemiplegia patients. The experimental and controls groups performed task practices for 30 minutes, 3 times per week for 28 weeks with and without taping, respectively. [Results] After treatment, there were significant differences in every outcome measures within each group except for the Brunnstrom recovery stage of the hand. However, there was a significant difference in functional independence movements between the groups. [Conclusion] Task practice has the same effectiveness regardless of the taping of the upper extremities. Nevertheless, taping is helpful for improving both the functions and activities of daily living in patients with hemiplegia.

Flotation column is widely used as the separation equipment for fine mineral due to its high selectivity. However, this device may be unsuitable for the coarse particle flotation and has high handling ability. A two-stage flotation column with dimensions of 2 000 mm×1 000 mm×4 000 mm was designed to enhance the column flotation process. The energy input was modified by adjusting the flow rate and the head of circulating pump. The flotation column was designed with low energy input in the first stage (speed flotation stage) to recover easy-to-float materials quickly, and high energy input in the second stage (recovery stage) to recover difficult-to-float minerals compulsorily. Contrast experiments on the throughput and coarse coal recovery of high ash coal from the Kailuan Mine were conducted using conventional single-stage flotation column and the two-stage flotation column. The results show that the combustible matter recovery of the two-stage flotation column is 5.25% higher than that of the conventional single-stage flotation column. However, the ash contents of clean coal for both columns are similar. Less coarse coals with low ash are obtained using the two-stage flotation column than that using the single-stage column flotation with the same handling ability. The two-stage flotation column process can enhance coal flotation compared with the conventional single-stage column flotation.

Er Wang Temple, in World Heritage Site "Dujiang Weirs and Qingchengshan Mountai", was severely destroyed in Wenchuan earthquake of May 2008. There are several problems at different level in every building, such as structural distortion, foundation displacement, wall fracture, roof damage, etc. The stage was completely collapsed in the earthquake. Tableland the stage situated had a huge crack and slope collapse. This article is for the stage renovation. The survey of damage in earthquake is the basis of Er Wang Temple restituting. Survey including field survey after the earthquake and the measurement and investigation for the remained construction member of the main wood structure. For field survey, the basis of pillars which had not have significantly affects in earthquake could be seem as the reference points for measurement. The investigation of remained main wood construction member, especially the size of the key structures and site and manufacture method of the joints, is the important basis for recovery stage. Our team did our utmost to restore the original appearance of stage in design, materials and craft by various tools, which include measured drawings in different times, old images collection, fine measuring by 3D laser scan, measurement of leftover pieces, logical inference.

To investigate the different expressions of protein spectra in sera from children with infectious mononucleosis (IM) at acute stage and recovery stage in order to screen out potential protein biomarkers for children IM, the fingerprints of serum protein were obtained from the healthy (controls), acute upper respiratory infection (AURI), acute IM and recovery IM children using surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) and gold chip technique. Data were analyzed by Biomarker Wizard 3.1 and diagnostic models were established by Biomarker Patterns System 5.0. Within the mass to charge (m/z) ratios, there were six protein peaks (five were down-expressed and one over-expressed) showing significant differences between the acute IM group and the control group (P 0.05). The established diagnostic model based on significative peak test, the specificity and the sensitivity of IM. All the analytical results suggested that the protein at 6421.5 (M/Z value) may be the serum biomarker for IM; the protein bank showed that the protein at 6421.5 is a new protein; the diagnostic models based on this peak could accurately distinguish acute IM from normal children, the recovery IM children. SELI-TOF-MS technology is an effective tool to search for disease-related proteins. Key words: Infectious mononucleosis (IM), proteomics, biomarker, artificial neural network.

The Hanshin-Awaji Earthquake of 1995 and has moved through the various phases into the recovery stage. After the earthquake we conducted two surveys involving approximately 8000 families with pre-school aged children and 466 families with disabled children. Symptoms related to PTSD were found more frequently in the small children whose houses had been severely damaged one year after the earthquake. Although the symptoms decreased, they were still present more frequently in the children and their mothers with severely damaged homes in 1998. Our results show children with intellectual or emotional disabilities displayed many behavioral problems. The physically disabled children required medical resources and specialized support in a structured environment. Both groups voiced the need to set up specialized facilities for people with disabilities. Following the Central Java Earthquake in 2006, we have engaged in "children house" activities in the disaster stricken area in collaboration with Gadjah Mada University. Through this activity, we have been able to share what works in helping children with disabilities and their families. From our experience we have found exchanging of information among the people in the disaster stricken areas helps to reduce the psychological damage of the children and aids in their recovery process.

Purpose: Dental implants though a successful treatment modality there exists controversies regarding the relationship between the adequacy of the keratinized gingiva (KG) and peri-implant health. The presence of an adequate amount of peri-implant KG reduces gingival inflammation and hence soft-tissue augmentation should be frequently considered. Among the various periodontal plastic surgical procedures, the apically displaced flap increases the width of keratinized tissue with reduced patient morbidity. The current study aims at evaluating the esthetic improvement in KG around dental implants applying apically positioned flap (APF) technique. Materials and Methods: A total of 10 endosseous dental implants were placed in eight systemically healthy patients. APF surgery was performed at the implant site on the buccal aspect either at the time of implant placement (one stage surgical protocol) or during the implant recovery stage (two stage surgical protocols) for increasing the width of KG and reviewed until 12 weeks post-operatively. The width of KG was evaluated at baseline and at the end of 12 weeks after surgery. Paired t-test was performed to evaluate the changes in the width of KG at baseline and at 12 weeks post-operatively. In addition, soft-tissue esthetic outcome was assessed by using visual analog scale (VAS). Results: The mean width of KG at baseline was 1.47 mm and 12 weeks post-operatively was 5.42 mm. The gain in KG from baseline was 3.95 mm with the P value of 0.000, which was highly statistically significant. The assessment of esthetic outcome using VAS gave an average score of 7.1 indicating good esthetics. Conclusion: The technique of APF yielded a significant improvement in keratinized tissue, which is both functionally and esthetically acceptable.

The period of gonads development was first studied from one to five years in the freshwater pearl mussel Hyriopisis schlegelii. It lasted for 36 months and was divided into three main stages: initiation of gonad formation, a stable growth phase, and a reproductive cell development phase. Each reproductive cycle consisted of five stages: proliferative stage (from late January to late February), growth stage (from late February to late March), maturation stage, spawning stage (from early April to late October) and recovery stage (from early November to late January). Interestingly, a hermaphroditic phenomenon was observed in this mussel for the first time, which appears during the development stage from 26 to 32 months. Male and female follicular tissues coexisted in hermaphrodite individuals with the male follicular tissue accounting for more than 90% of the whole gonad tissue. No hermaphroditic phenomenon was observed in matured gonad. We thus speculate that self-fertilization does not exist in H. schlegelii.

Machine transplantation results in serious transplant shock in seedlings and results in a longer recover stage, which negatively impacts the growth of low-position tillers and the yield of machine-transplanted rice. A barrel experiment was conducted to examine the effect of the foliar application of triacontanol (TRIA) on machine-transplanted rice during the recovery stage. TRIA (0, 1, 5, and 10 μM) was sprayed over leaves 2 days before transplanting. The chlorophyll content, sucrose content, oxidative damage, antioxidant enzyme levels, glutathione (GSH), and ascorbate (ASA) redox states, tiller dynamics and yield components of the plants were investigated. The results show that foliar-applied TRIA significantly alleviates the growth inhibition and oxidative damage caused by transplant shock. Furthermore, the application of TRIA increased the chlorophyll and sucrose contents of the plants. Importantly, TRIA not only significantly improved the activity of catalase (CAT) and guaiacol peroxidase (POD), demonstrating that POD can play an important role in scavenging H2O2 during the recovery stage, but it also enhanced the redox states of ASA and GSH by regulating the activities of enzymes involved in the ASA-GSH cycle, such as ascorbate peroxidase (APX) and glutathione reductase (GR). A dose of 10 μM TRIA was the most efficient in reducing the negative effects of transplant shock, increasing the panicles, grain filling, and grain yield per hill by 17.80, 5.86, and 16.49%, respectively. These results suggest that TRIA acts to reduce transplant shock in association with the regulation of the redox states of ASA and GSH and antioxidant enzymes and serves as an effective antioxidant to maintain photosynthetic capacity and promote the occurrence of low tillers.

[Purpose] The aim of this study was to clarify the relationships among muscle fiber conduction velocity, time-force characteristics of muscle force production, and voluntary movement in patients with hemiplegia. [Subjects and Methods] The participants in the present study were 13 patients with hemiplegia. Muscle fiber conduction velocity, deep temperature of muscles and muscle thickness were measured for the tibialis anterior, and a time force curve was obtained from dorsiflexion of the ankle and lower thigh girth (maximum, minimum) for both sides. The maximum torque rate of change and maximum torque were calculated from the force-time curve. In addition, Brunnstrom Recovery Stage was used to evaluate the function of the hemiplegic side. [Results] In all the measurement items, significant differences were observed between the hemiplegic side and the healthy side. The maximum torque rate of change and Brunnstrom Recovery Stage showed a high degree of correlation. The muscle fiber conduction velocity and maximum torque rate of change or maximum torque showed a medium degree of correlation. However, muscle fiber conduction velocity was not significantly correlated with Brunnstrom Recovery Stage. [Conclusion] Brunnstrom Recovery Stage was good as a determination factor for the maximum torque rate of change. In addition, in patients with hemiplegia, it became clear that relationship is between muscle fiber conduction velocity and time-force characteristics of muscle force production as in healthy persons.

Hydrocephalus is a condition characterised by enlarged cerebral ventricles, which in turn affects intracranial pressure (ICP); however, the mechanisms regulating ICP are not fully understood. A nonlinear signal processing approach was applied to ICP signals measured during infusion studies from patients with two forms of hydrocephalus, in a bid to compare the differences. This is the first study of its kind. The two forms of hydrocephalus were idiopathic normal pressure hydrocephalus (iNPH) and secondary normal pressure hydrocephalus (SH). Following infusion tests, the Lempel-Ziv (LZ) complexity was calculated from the iNPH and SH ICP signals. The LZ complexity values were averaged for the baseline, infusion, plateau and recovery stages of the tests. It was found that as the ICP increased from basal levels, the LZ complexities decreased, reaching their lowest during the plateau stage. However, the complexities computed from the SH ICP signals decreased to a lesser extent when compared with the iNPH ICP signals. Furthermore, statistically significant differences were found between the plateau and recovery stage complexities when comparing the iNPH and SH results (p = 0.05). This Letter suggests that advanced signal processing of ICP signals with LZ complexity can help characterise different types of hydrocephalus in more detail.

S.S. Nikiforova, swetl.nik2010@yandex.ru, A.I. Yakovlev, yak-alexandr@yandex.ru Chelyabinsk Regional Children’s Hospital, Chelyabinsk, Russian Federation. Никифорова Светлана Сергеевна, анестезиолог-реаниматолог, Челябинская областная детская клиническая больница, г. Челябинск, swetl.nik2010@yandex.ru. Яковлев Александр Игоревич, анестезиолог-реаниматолог, Челябинская областная детская клиническая больница, г. Челябинск, yak-alexandr@yandex.ru. Aim. Based on publications dedicated to anesthetic management for surgery of children with brain neoplasms we aimed to reveal and summarize the specific features of anesthesia of such patients. Materials and Methods. We performed a systematic review and processed the information from Russian and foreign literature published in 2001–2016. The analysis included patients younger than 18 who had undergone surgical procedures due to brain tumor. Results. The conducted analysis allowed us to classify surgical interventions into three main categories (shunt surgery, open surgery, neuroendoscopy) and to determine category-specific features of anesthetic management. The analysis results also made it possible to describe the algorithms of preoperative preparation, recovery stage, and early postoperative period for anesthesiologist. Conclusion. The review has shown that brain tumor surgery is one of the most complicated operations requiring a well-coordinated teamwork. Anesthesiologist has not only to be especially well-trained and skilled, but to cooperate closely with neurosurgeon, which may be even more critical. Psychological, ethical, and professional aspects of such cooperation are a subject of further detailed research. Цель. Основываясь на обзоре публикаций, посвященных оказанию анестезиологического пособия при оперативных вмешательствах у детей с новообразованиями головного мозга, выявить и обобщить специфические особенности проведения анестезии у таких пациентов. Материалы и методы. Мы сделали системный обзор, обработав информацию из российских и зарубежных источников, изданных в период с 2001 по 2016 г. Анализировались данные о пациентах младше 18 лет, подвергшихся оперативному вмешательству в связи с опухолью головного мозга. Результаты. Проведенный анализ позволил подразделить оперативные вмешательства на три основные категории (шунтирующие операции, открытые вмешательства, нейроэндоскопические операции) и определить особенности анестезиологического пособия для каждой из категорий. Также был сформулирован алгоритм действий анестезиолога при подготовке пациента к операции, при пробуждении и в раннем послеоперационном периоде. Заключение. Обзор показал, что оперативные вмешательства при новообразованиях головного мозга относятся к наиболее сложным и требующим слаженной работы всей операционной бригады. Помимо высокой квалификации специалиста, проводящего анестезиологическое пособие, критически необходимо тесное сотрудничество анестезиолога и нейрохирурга. Психологические, этические и профессиональные аспекты такого сотрудничества должны быть изучены более подробно в дальнейших исследованиях.

Lack of contraceptive choices which meet the requirements is one of the contributing factors to less participation of man in contraceptive use. This research aimed to study the effectiveness of natural material for alternative male contraception, by injecting papaya seed extract with Cibinong variety (Carica papaya L.) to long tail monkey (Macaca fascicularis L). The research was conducted at Primates Study Center, Institute of Agriculture, Bogor. Total samples of this research were 8 monkeys, with three intervention groups and one control group. Papaya seed extract was injected via intramuscular in 21 days, with dose for each group were 40 mg/monkey, 80 mg/monkey, and 120 mg/monkey. Data analysis of spermatozoa quality (motility, viability, morfology) was done by using Cochran test before and after intervention stages, and during recovery stage. Meanwhile, data aalysis of spermatozoa concentration and testosterone hormone level was done by using Friedman test. Result of this reseach demonstrated reduction of motility, viability, and morfology of spermatozoa after inejction of papaya seed extract and increase to normal level at recovery stage (p ≤0.05). These results was supported with cement aglutination. The most effective dose was at 40 mg/monkey/day, with reduction of spermatozoa motility from 87.5 % to 40%, and reduction of testosterone level from 2.35 ng/mL to 1.83 ng/mL. Even though spermatozoa motility and testosterone hormone level reduced, but its conditions were still in good condition category.

Several clinical and government reviews have recommended specialised rehabilitation services for those recovering from neurological insult or neurosurgical intervention. Despite this, provision of 'rapid access'/acute neurorehabilitation units is extremely limited in the UK. In some areas, millions of people have no access to such facilities. Numerous articles have indicated that delayed access to neurorehabilitation in the acute recovery stage may worsen clinical outcomes and increase length of stay for patients. However, there has been a lack of studies directly comparing clinical outcomes between matched samples of patients in acute neurorehabilitation units versus patients receiving treatment-as-usual. In a study believed to be the first of its kind, this paper: (A) Describes the rationale and evidence base for acute neurorehabilitation. (B) Provides a comparison of clinical outcome scores Functional Independence Measure/Functional Assessment Measure (FIM-FAM) and also length of stay times for both of the aforementioned groups. The results show that all outcome areas except the 'communication' domain saw clinically and statistically significant improvements in the acute neurorehabilitation group. Length of stay was significantly reduced in the acute neurorehabilitation group. The case for reviewing the provision of acute neurorehabilitation units is now even more urgent and difficult to ignore.

The aim of this study was to investigate the cumulative effects of intensive resistance training on salivary immunoglobulin A (SIgA) and cortisol responses in elite male weightlifters. Eleven elite male Taiwanese weightlifters were trained through 3 training stages before a national weightlifting competition, and this was followed by a 2-week recovery stage. Resting saliva samples were collected once in each of the 4 stages. Salivary concentrations of total protein (TP), SIgA, lactoferrin, and cortisol were measured. The results showed that (a) salivary TP concentrations were not significantly affected; (b) resting levels of SIgA, the ratio of SIgA to TP (SIgA/TP), cortisol, and the ratio of cortisol to TP (cortisol/TP) were significantly higher in the training stages than in the recovery stage; (c) a positive correlation was revealed between the ratios of SIgA/TP and cortisol/TP; and (d) the resting salivary lactoferrin concentrations and the ratio of lactoferrin to TP (lactoferrin/TP) were significantly lower in stage 1 than in the recovery stage. The findings in this study suggest that prolonged, intensive resistance training exerts cumulative effects on SIgA and cortisol responses in elite weightlifters.

Aqueous two-phase systems (ATPS) have been studied and used for product recovery and purification from diverse biological sources. ATPS are characterized by their versatility, easy scale up parameters, process integration capability and relative low cost. This technique is commonly regarded as a primary recovery stage mainly due to its low selectivity. However, the use of strategies involving the modification of ATPS with affinity ligands have resulted in significant increases in recovery yields and purification folds of biological products. The aim of this review is to highlight current applications, trends and challenges regarding affinity partitioning in aqueous two-phase systems for the fractionation, recovery and purification of biological products.

The effects of temperature, stress level and hygrothermal aging on the creep-recovery behaviors of anisotropic conductive adhesive film (ACF) were investigated experimentally using a dynamic mechanical analyzer (DMA). It is found that the initial strains, instantaneous strains, and creep or recovery rates increase with increasing temperature，however decrease with increasing hygrothermal aging time. The change of creep or recovery rates at low temperature is apparent, however the creep or recovery rates increase obviously at temperatures above 25 oC with increasing stress level. For the hygrothermal aged ACF, the time to reach steady creep stage or steady recovery stage is reduced significantly compared with the unaged sample. The strain jumps at instantaneous loading decrease visibly and the strain jumps at instantaneous unloading decrease slightly with increasing aging time. And the strain jumps at instantaneous loading and unloading increase with increasing stress level for the unaged and aged ACFs.

We analyze the resilience of U.K. regions to employment shocks. Two basic notions of resilience are distinguished. With engineering resilience, there is an underlying stable growth path to which a regional economy rebounds following a shock. With ecological resilience, shocks can permanently affect the growth path of the regional economy. Our data set consists of quarterly employment series for 12 U.K. regions (NUTS I) for the period 19712010. Using a seemingly unrelated regression (SUR) model specification, we test for the relevance of (engineering) resilience of U.K. regional employment to the four recessionary shocks in our sample. It turns out that U.K. regions do indeed differ in their resilience, but that these differences mainly concern the initial resistance to these shocks and not so much the recovery stage. The SUR model does not allow shocks to have permanent effects and it also does not take the possibility of time differentiated shock spillovers between the 12 regions into account. To this end, we also estimate a vector error-correction model (VECM) specification where employment shocks can have permanent effects and where also interregional employment linkages are included. We find that employment shocks typically have permanent effects when it concerns the own-region effects. Permanent effects can also be found for the impact on other regions but the interregional effects are typically only significant for nearby regions.