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Featured Application: The additional weight carried in a vest during trail running affects performance and physiological milestones unevenly. Running power appears to be more stable than speed for monitoring training load, particularly at velocities below the second ventilatory threshold. Background: The biomechanical and physiological adaptations to resisted running have been well documented in sprinting; however, their impact at submaximal speeds, such as those typical of long-distance running, remains unclear. This study aimed to evaluate the impact of running with a weighted vest, loaded with 5% and 10% of body mass, on the physiological and mechanical variables of trained trail runners. Methods: Fifteen male trail runners completed an incremental protocol to exhaustion on a treadmill with 0%, 5%, and 10% of their body mass (BM), in random order, with one week of separation between the tests. The maximality of the test was confirmed by measuring lactate concentrations at the end of the test. Oxygen consumption ( V ˙ O2) and respiratory exchange ratio (RER) were recorded using a portable gas analyzer (Cosmed K5), and ventilatory thresholds 1 and 2 (VT1, VT2) were calculated individually. Running power was averaged for each speed stage using the Stryd device. Finally, the peak values and those associated with VT1 and VT2 for speed, power (absolute and normalized by body mass), V ˙ O2, RER, and the cost of transport (CoT) were included in the analysis. Results: One-way repeated-measures ANOVA revealed a detrimental effect of the extra load on maximum speed and speed at ventilatory thresholds (p ≤ 0.003), with large effect sizes (0.34–0.62) and a nonlinear trend detected in post hoc analysis. Conclusions: Using running power to control the intensity of effort while carrying extra weight provides a more stable metric than speed, particularly at aerobic intensities. Future research in trail running should investigate the effects of weighted vests across various terrains and slopes. [ABSTRACT FROM AUTHOR]

This study aimed to explore the effect of the menstrual cycle (MC) phases (i.e., early follicular phase [EFP], late follicular phase [LFP], and mid-luteal phase [MLP]) on the repetitions performed to momentary failure in back squat and bench press exercises, as well as to determine subsequent fatigue (i.e., change in countermovement jump [CMJ], perceived effort, and muscle soreness). Twelve physically active eumenorrheic women performed a back squat and bench press set to momentary failure at 80% of the one-repetition maximum during the EFP, LFP, and MLP. The results revealed that subjects were able to perform 2.2 [0.2 to 4.2] more repetitions in the LFP with respect to the EFP for the back squat exercise (p = 0.009), but no significant differences were observed for the bench press (p = 0.354). The EFP displayed a larger CMJ height drop (−0.86 [−1.71 to −0.01] cm) with respect to the LFP (0.01 [−0.57 to 0.58] cm) and the MLP (−0.36 [−1.15 to 0.43] cm). Neither the perceived effort of each set to failure nor the resulting muscle soreness differed between MC phases. Therefore, practitioners should be aware that the MC could condition the repetitions available to momentary failure and the resulting allostatic load. [ABSTRACT FROM AUTHOR]

In this study we aimed to test if acute strength exercise would induce cognitive improvements. Secondarily, we examined the relationship between exercise-induced changes in cognitive function and postural dual-task control. Thirty-seven cognitively intact, non-faller older adults (≥60 years) were nonrandomly allocated to strength exercise or control. Strength exercise consisted of Smith machine squats (one session, 3 × 3reps at 90%, 95%, and 100% one-repetition maximum). Control participants held seated rest for 45 min. Cognitive functions, recognition (memory search), working memory (mathematical processing), processing speed (2-choice reaction time), and postural dual-task control were tested before and immediately after exercise or control using the Automated Neuropsychological Assessment Metrics-4 (ANAM4) battery and a mathematical counting task while maintaining a tandem Romberg stance with eyes open on a force plate. Outcome measures were response time and performance index (100 × [accuracy/response time]) on the ANAM4 tests and sway activity and entropy during the postural dual-task. We found a non-significant improvement with moderate effect size in performance index on the mathematical processing task of experimental participants compared to control participants (p = 0.145, $\eta _p^2$ η p 2 = 0.060). Improvements in the mathematical processing task over time in the control group were associated with increased sway activity during the postural dual-task. No significant associations were found between changes in cognitive function and changes in postural control in the experimental group. Ultimately, our results may direct researchers and healthcare professionals in designing the optimal exercise treatment to improve cognitive function and postural control in older adults. [ABSTRACT FROM AUTHOR]

Background: Athletes with patellar tendinopathy (PT) have postural stability deficits; however, the underlying mechanisms and factors responsible remain unknown. The effect on postural stability in PT of decreased quadriceps strength, altered proprioception, lower-limb muscle tightness, and knee pain, which explain postural stability deficiency in other populations, is uninvestigated. Hypothesis: Proprioceptive acuity, muscle tightness, quadriceps strength, and pain predict postural stability in athletes with PT. Study Design: Cross-sectional comparative study. Level of Evidence: Level 2. Methods: A total of 43 athletes with PT and 43 healthy athletes were enrolled. Static and dynamic postural stability, proprioceptive acuity, muscle tightness, quadriceps strength, and pain were evaluated using a force platform, Y-balance test (YBT), a weight discrimination protocol, a goniometer, an isometric dynamometer, and a valid questionnaire, respectively. Results: Athletes with PT had significantly worse static and dynamic postural stability in the affected limb (AL) compared with the nonaffected limb (NAL) (P < 0.01) and the control group (P < 0.01). Athletes suffering from PT revealed lower quadriceps strength (P < 0.01), proprioceptive acuity (P = 0.02), and higher muscle tightness in the AL compared with the NAL and controls. Quadriceps weakness of the AL and pain in athletes with PT explained the variance of dynamic postural stability impairment. Conclusion: Athletes with PT have postural stability deficiency compared with healthy peers. Our results demonstrate that quadriceps muscle weakness and pain are the factors that explain postural stability impairment. Clinical Relevance: These results can assist clinicians in the design of therapeutic balance rehabilitation programs by acting not only on pain relief but also on quadriceps strengthening through resistance training to avoid subsequent injuries in athletes with PT. [ABSTRACT FROM AUTHOR]

In this work, themechanical principles of external fixation and resistance training for the wrist affected by a distal radius fracture (DRF) are revealed. Based on the biomechanical analysis, two wearable exoskeleton devices are proposed to facilitate the DRF rehabilitation progress. Chronologically, the adjustable fixation device (AFD) provides fixed protection and limited mobilization of the fractured wrist in the early stage, while the functional recovery of relevant muscles is achieved by the resistance training device (RTD) in the later stage. According to the designedmechatronic systems of AFD and RTD, the experimental prototypes for these two apparatuses are established. By experiments, the actual motion ranges of AFD are investigated, and the feasibility in monitoring joint angles are validated. Meanwhile, the resistant influences of RTD are analyzed based on the surface electromyography (sEMG) signal features, the results demonstrate that the training-induced muscle strength enhancement is generally increased with the increment in external resistance. The exoskeleton devices presented in this work would be beneficial for the active rehabilitation of patients with DRF. [ABSTRACT FROM AUTHOR]

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Retos: Nuevas Perspectivas de Educación Física, Deporte y Recreación is the property of Federacion Espanola de Asociaciones de Docentes de Educacion Fisica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND Total hip replacement is routinely recommended for severe hip osteoarthritis, but data from randomized trials are lacking regarding comparison of the effectiveness of this procedure with that of nonsurgical treatment such as resistance training. METHODS We conducted a multicenter, randomized, controlled trial to compare total hip replacement with resistance training in patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery. The primary outcome was the change in patient-reported hip pain and function from baseline to 6 months after the initiation of treatment, assessed with the use of the Oxford Hip Score (range, 0 to 48, with higher scores indicating less pain and better function). Safety was also assessed. RESULTS A total of 109 patients (mean age, 67.6 years) were randomly assigned to total hip replacement (53 patients) or resistance training (56 patients). In an intention-to-treat analysis, the mean increase (indicating improvement) in the Oxford Hip Score was 15.9 points in patients assigned to total hip replacement and 4.5 points in patients assigned to resistance training (difference, 11.4 points; 95% confidence interval, 8.9 to 14.0; PcO.001). At 6 months, 5 patients (9%) who had been assigned to total hip replacement had not undergone surgery, and 12 patients (21%) who had been assigned to resistance training had undergone total hip replacement. The incidence of serious adverse events at 6 months was similar in the two groups; the majority of such events were known complications of total hip replacement. CONCLUSIONS In patients 50 years of age or older who had severe hip osteoarthritis and an indication for surgery, total hip replacement resulted in a clinically important, superior reduction in hip pain and improved hip function, as reported by patients, at 6 months as compared with resistance training. [ABSTRACT FROM AUTHOR]

Introduction: The aim of this study was to investigate the effects of blood flow-restrictive resistance training (BFR-RT) on improving metabolic abnormalities, blood pressure (BP), obesity, and 10-year atherosclerotic cardiovascular disease (ASCVD) risk in middle-aged patients with type 2 diabetes mellitus (T2DM). Method: We conducted a parallel-group, single blind randomized controlled trial. Participants who met the inclusion criteria were randomly divided into control group, BFR-RT group and aerobic exercise (AE) group. Control group received health education and follow-up; Two exercise groups received supervised collective training for a period of six months, three times per week. AE group trained at moderate-intensity for 60 minutes each time, while BFR-RT group trained at low-intensity for 40 minutes each time. The primary outcomes were change in 10-year ASCVD risk index and level, and the secondary outcomes included changes in fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c), blood lipids, BP, and obesity level within and across the three groups at baseline, the third and sixth months of intervention. Result: Among 93 individuals (control group, n=31; AE, n=30; BFR-RT, n=32) were analyzed. At baseline, there were no significant differences in various indicators among the three groups (p>0.05). After intervention, the 10-year ASCVD risk index and risk level of both exercise groups significantly decreased compared to the control group and baseline (p<0.05), and the risk reduction became more pronounced over time. In the sixth month of intervention, the 10-year ASCVD risk index in the AE group decreased by 27.40%, and that in the BFRRT group decreased by 26.78%. Meanwhile, apart from lipoprotein (a) and diastolic blood pressure, both exercise groups showed significant improvements in FPG, HbA1c, dyslipidemia, systolic blood pressure, and obesity indicators compared to the control group and baseline (p<0.05). There was no significant difference in various indicators between the two exercise groups (p>0.05). Conclusion: BFR-RT could reduce the 10-year ASCVD risk in middle-aged T2DM patients for by improving metabolic abnormalities, BP and obesity, and its effect was similar to that of moderate-intensity AE. [ABSTRACT FROM AUTHOR]

Background: Medial tibial stress syndrome (MTSS) is a prevalent running-related injury that could impact athletic performance and quality of life. The purpose of the study was to investigate the effectiveness of functional hip abductor strength training on reducing contralateral pelvic drop angle (hip frontal plane projection angle), and dynamic knee valgus (knee frontal plane projection angle) in runners with medial tibial stress syndrome (MTSS). Methods: Forty male and female recreational runners were diagnosed with MTSS for at least one month. The age ranged from 25 to 35 years old, and the body mass index (BMI) ranged between (18.5 and 25 kg/m2) participated in this study. This was a single-blind, randomized controlled trial. Participants were randomized into two groups: a control group (Group A, n = 20) received a selected physical therapy exercise program, and an experimental group (Group B, n = 20) received the same program plus functional hip abductor strength training. Dynamic knee valgus (frontal plane projection angle) and contralateral pelvic drop angle were measured using 2D video and analyzed by Kinovea software at baseline and after 8 weeks. Mixed-effect multifactor analysis of variance (MANOVA) was conducted to compare within and between groups effects on FPPA and pelvic drop angle. Results: After 8 weeks, Group B exhibited a significantly decreased frontal plane projection and pelvic drop angles compared to Group A (p < 0.05). Group A also demonstrated a reduced pelvic drop angle, but to a lesser extent, and their frontal plane projection angle increased. Conclusions: This study demonstrates that 8 weeks of functional hip abductor strength training, combined with traditional physical therapy, effectively improves lower extremity kinematics in runners with MTSS by reducing dynamic knee valgus and contralateral pelvic drop. This targeted approach likely addresses underlying muscle weakness and movement dysfunction, offering hope for potentially reducing MTSS recurrence. Trial registration: clinicaltrials.gov. NO: NCT05637476. Date: December 1, 2022. [ABSTRACT FROM AUTHOR]

Limited chest expansion and asymmetry in the respiratory muscles after a stroke lead to poor ventilation and reduced physical performance.To determine the effect of chest expansion resistance exercise and respiratory muscle stretching on respiratory function and gait endurance in patients with stroke.Thirty stroke patients were randomly assigned to a chest expansion resistance group (CERG), a respiratory muscle stretching group (RMSG), and a control group (CG). CERG and RMSG received chest expansion resistance and respiratory muscle stretching, respectively, 3 times a week for 8 weeks. Respiratory function, respiratory muscle strength, and gait endurance were measured before and after the intervention period.The experimental groups, CERG and RMSG, showed significant improvements in respiratory function variables (p < .05). For respiratory muscle strength variables, maximal inspiratory pressure (MIP) in the CERG and maximal expiratory pressure (MEP) in the RMSG showed significant changes compared to the CG (p < .05). Both CERG and RMSG also showed significant improvements in the 6MWT compared to the CG (p < .05).Chest expansion resistance exercise would be a more effective method, while both chest expansion resistance exercise and respiratory muscle stretching are helpful in improving respiratory function and gait endurance. [ABSTRACT FROM AUTHOR]

AbstractObjective: To examine the association of muscle-strengthening activity with total alcohol consumption (AC) and binge drinking (BD). Participants: College students (n = 1623) from a large United States university. Methods: Students self-reported their physical activity (PA), AC, and socio-demographic characteristics via an online survey. Hierarchical regression models were computed to examine the association of aerobic PA, and muscle-strengthening activity with total AC and BD. Results: After adjusting for socio-demographic characteristics and aerobic PA, muscle-strengthening activity and achieving muscle strengthening activity recommendations explained a significant proportion of unique variance in total AC (β = .16, p < .001 and β = .16, p < .001, respectively). Similarly, with each additional day of muscle-strengthening activity the odds of reporting BD were 20.9% higher, and individuals who met muscle-strengthening activity recommendations had 93.2% higher odds of reporting BD. Conclusions: Muscle-strengthening activity should be accounted for when examining the relationship between PA and AC. [ABSTRACT FROM AUTHOR]

Aging has made stroke a top killer and disabler, with post-stroke sarcopenia worsening disability and quality of life. While resistance training benefits the elderly, its impact on stroke patients is understudied. This study evaluates the potential of a 4-week unilateral resistance training (URT) program to prevent sarcopenia in stroke patients. It assesses the impact of URT on hand grip strength (HG), muscle thickness (MT), upper limb functionality, and the psychological status of the patients. The study aims to quantitatively analyze these indicators to inform evidence-based post-stroke rehabilitation practices. This study employed a randomized controlled trial (RCT) involving 77 eligible stroke survivors, equally allocated into a control group (n = 39) and an intervention group (n = 38). The control group received standard rehabilitation, while the intervention group additionally underwent a 4-week URT program. The primary outcomes were unaffected side HG and MT, measuring muscle mass and function. Secondary outcomes included the Fugl-Meyer Assessment of the Upper Extremity (FMA-UE) for upper limb functionality and the Hamilton Depression Rating Scale (HAMD) for psychological well-being changes. Statistical analysis showed significant differences (p < 0. 05) in all measured parameters between the intervention and control groups after the 4-week period. Intra-group comparisons also indicated substantial improvements (p < 0. 05). Unilateral resistance training significantly mitigates muscle atrophy in stroke patients, preventing sarcopenia and enhancing upper limb function. It also ameliorates depressive symptoms, improving rehabilitation outcomes and overall quality of life. [ABSTRACT FROM AUTHOR]

Alzheimer's disease (AD) is rapidly becoming one of the most expensive, burdening, and deadly diseases of this century. Up to now, there is still a lack of pharmacotherapy with substantial efficacy, and physical exercise is a promising and low‐cost way to aid in delaying the process of AD. The aim of this review is to summarise the efficacy of different physical exercise approaches and doses in the management of AD, including aerobic exercise, resistance exercise and multicomponent exercise. A literature search using MeSH terms for each topic is undertaken using PubMed and the Web of Science Core Collection database, supplemented by hand searching for additional references. Retrieved articles were reviewed, synthesised, and summarised. This review shows that aerobic exercise has been almost unanimously recognised for the improvement of cognition, neuropsychiatric symptoms and activities of daily living. Resistance exercise also shows a good prospect in the above aspects and has a unique advantage in enhancing muscle strength, while multicomponent physical activity does not seen to significantly improve cognitive function. Each type of exercise has a dose effect, but for individuals with AD, the most appropriate exercise dose is still controversial. [ABSTRACT FROM AUTHOR]

The aim of this study was to examine the effects of free swimming (FS), aquatic resistance training (ART), and their combination (FS&ART) on the body composition, blood pressure, and physical fitness of older adults. The study employed a randomized controlled design, comparing three experimental groups with a control group. Eighty volunteers aged between sixty and seventy years (age: 66.2 ± 2.3 years; body mass index: 25.8 ± 4.3 kg/m²) participated in the 16-week intervention, consisting of two weekly sessions. Assessments were conducted at baseline and post-intervention, including anthropometric measurements, blood pressure readings, and the Senior Fitness Test. Significant differences were found between groups in post-intervention considering the chair stand test (p = 0.017; ES = 0.125), arm curl test (p = 0.029; ES = 0.111), 8-foot up and go test (p = 0.042; ES = 0.102), and walk test − 6 min (p = 0.005; ES = 0.156). Specifically, both ART (+ 20.1%; p < 0.05) and FS&ART (+ 19.5%; p < 0.05) showed significantly greater improvements in the chair stand test compared to the control group. Similarly, ART (+ 23.1%; p < 0.05) and FS&ART (+ 18.7%; p < 0.05) performed better than the control group. FS&ART also exhibited a significant improvement over the control group in the 8-foot up-and-go test (+ 14.6%; p < 0.05). In the 6-minute walk test, FS (+ 19.4%; p < 0.05) and FS&ART (+ 15.9%; p < 0.05) both significantly outperformed the control group. This study found that FS improves cardiovascular endurance, while ART enhances muscular strength and endurance in older adults, with combined benefits for agility, suggesting integration of combined modalities into community wellness initiatives for enhanced physical fitness and health outcomes. [ABSTRACT FROM AUTHOR]

AbstractObjectivesMaterials and MethodsResultsConclusions\nIMPLICATIONS FOR REHABILITATIONThis study investigated whether exercising with different relative loads would be associated with different experienced pain intensities in individuals with patellar tendinopathy.We recruited 14 individuals with patellar tendinopathy for this randomized crossover study. In a randomized order, participants performed one set of single-legged leg presses during one session with three relative loads (6 repetition maximum (RM), 10RM, and 14RM). The primary outcome was pain during exercise measured on a 0–10 Numerical Rating Scale (NRS) (0 = no pain, 10 = worst pain), which participants rated after performing the exercise set with each relative load.No differences in pain during either of the three relative loads were observed (F(2, 26) = 0.06, p = 0.942). The participants’ experienced pain was 4.5 NRS (SD1.7), 4.5 NRS (SD1.7), and 4.6 NRS (SD2.0) during the 6RM, 10RM, and 14RM loads, respectively. A secondary analysis revealed no statistically significant difference in pain intensity between the performance of the first, second, or third exercise set regardless of the load (F(2, 26) = 1.06, p = 0.367).There was no difference in pain intensity during either relative load among individuals with patellar tendinopathy. Therefore, higher loads may be applied, associated with enhanced tendon adaptation.Clinicians may tend to decrease the load if the patient suffering from patellar tendinopathy expresses pain despite no evidence supporting that reducing the load will change the pain intensity during exercise.This study found that all loads (6RM, 10RM, and 14RM) were associated with the same pain experience.Pain did not vary with different exercise loads and, therefore, should not be used as the primary guide for load selection.Clinicians may tend to decrease the load if the patient suffering from patellar tendinopathy expresses pain despite no evidence supporting that reducing the load will change the pain intensity during exercise.This study found that all loads (6RM, 10RM, and 14RM) were associated with the same pain experience.Pain did not vary with different exercise loads and, therefore, should not be used as the primary guide for load selection. [ABSTRACT FROM AUTHOR]

Background Objectives Methods Results Conclusion The worldwide prevalence of diabetes is increasing, particularly among older adults. Understanding the association between muscle strength and mortality in this population is crucial for developing targeted exercise recommendations.To assess the prospective association of muscle strength with mortality in older adults with diabetes.From the Survey of Health, Ageing and Retirement in Europe (SHARE) study, spanning 28 countries, we included 16 149 diabetic adults aged 50 years and older (mean age 68.2 [standard deviation, SD, 9.2] years). Participants fulfilled two criteria: (1) diabetes diagnosis (ever) and (2) current use of diabetes medication. Muscle strength was assessed using handgrip dynamometry (unit: kg). Using time‐varying Cox regression with restricted cubic splines, we determined the prospective association of muscle strength with all‐cause and cause‐specific mortality, controlling for various confounders.Over a mean follow‐up of 5.9 years (SD 3.8), 2754 participants died (17%). Using the median level of muscle strength as reference (30 kg), lower and higher levels were associated in a curvilinear fashion with higher and lower all‐cause mortality risk, respectively. The 10th percentile of muscle strength (17 kg) showed a hazard ratio (HR) of 1.65 (95% confidence interval (CI) 1.53–1.79). The 90th percentile (47 kg) of muscle strength showed a HR of 0.55 (95% CI 0.49–0.63). A somewhat similar pattern, with varying strength of associations, was seen for mortality due to cardiovascular disease (CVD), respiratory disease, severe infectious disease, digestive system disease and cancer.Muscle strength is gradually and inversely associated with all‐cause and cause‐specific mortality risk in older adults with diabetes. As muscle strength is highly adaptable to resistance training at all ages, the present findings highlight the importance of improving muscle strength in older adults with diabetes. [ABSTRACT FROM AUTHOR]

The study investigated the influence of mental fatigue on older people’s enjoyment during a series of physical exercises. Using a randomized cross-over design, participants (n = 35) completed a 6-minute walking test − 6MWT, a Timed Up and Go—TUG test and three sets of knee extension exercise (first set: KE1, second set: KE2, third set: KE3) under two experimental conditions (control or mental fatigue). The Nonparametric Analysis of Longitudinal Data in Factorial Experiments was used to compare the number of repetitions performed during three sets of resistance exercise between conditions. The same analysis method was applied to compare the perception of effort and enjoyment across five moments (Post-6MWT, Post-TUG, Post-KE1, Post-KE2, Post-KE3) and two conditions and the Visual Analogue Scales (VAS) across four moments (baseline, Pre-6MWT, Pre-TUG, Pre-KE) and two conditions. Mental fatigue did not affect the physical function, perception of effort and enjoyment of exercise in older people. Participants, however, reported higher enjoyment for walking and dynamic balance compared to strength exercise. Mental fatigue had no effect on the physical function, perception of effort and enjoyment of exercise of older people. Participants presented a higher enjoyment for walking and dynamic balance compared to strength exercise. Given the importance of resistance exercises for health, clinicians should prioritize resources to education programs emphasizing the benefits of resistance exercise in both short- and long-term health. Including social interaction opportunities in physical exercise programs and prescribing activities appropriate to participants’ ability levels could enhance engagement and adherence. [ABSTRACT FROM AUTHOR]

The aim of the study was to examine the effects of a 5-week dynamic finger flexor strength training program on bouldering performance and climbing-specific strength tests. Advanced to elite level boulderers (n = 31) were randomized to a dynamic finger strength training group (DFS) or a control group (CON). The DFS training program consisted of 3 weekly sessions (3–5 sets, 4–10 repetitions per session). Both groups continued bouldering training as usual throughout the intervention period. Pre- and post-intervention measures included bouldering performance, maximal dynamic finger strength, isometric finger strength (peak and average force), and rate of force development (RFD). The DFS demonstrated greater improvement in dynamic finger strength (11.5%, 3.9 kg) than the CON (5.3%, 1.7 kg; p = 0.075, ES = 0.90), but there were no differences between the groups in 1RM (p = 0.075, ES = 0.67), bouldering performance (p = 0.39, ES = 0.35), isometric finger strength (p = 0.42–0.56, ES = 0.20–0.22) or RFD (p = 0.30, ES = 0.46). The DFS improved dynamic (p < 0.01, ES = 1.83) and isometric peak and average (p < 0.01, ES = 0.98, and p < 0.01, ES = 0.75, respectively) finger strength, while the CON only increased dynamic finger strength (p < 0.05, ES = 0.58). None of groups improved bouldering performance or RFD (p = 0.07–0.58). In conclusion, 5 weeks of DFS training improving dynamic strength to a greater extent than bouldering alone in addition to improving isometric finger strength among advanced boulderers. Isolated bouldering improved dynamic finger flexor strength, but importantly, increased finger strength (dynamic or isometric) did not improve bouldering performance. [ABSTRACT FROM AUTHOR]

Background: Exercise-induced oxidative stress and inflammation can impair muscular function in humans. The antioxidant and anti-inflammatory properties of molecular hydrogen (H2) highlight its potential to be as an effective nutritional supplement to support muscular function performance in healthy adults. However, the effects of H2 supplementation on muscular endurance performance in trained individuals have not been well characterized. This study aimed to assess the effects of intermittent hydrogen-rich water (HRW) supplementation before, during, and after resistance training on muscular endurance performance, neuromuscular status, and subjective perceptual responses after a 48-h recovery period. Methods: This randomized, double-blinded, placebo-controlled cross-over study included 18 trained men aged 19.7 ± 0.9 years. Participants in this study were instructed to consume 1,920 mL of HRW or pure water (Placebo) daily for 7 days. Additionally, participants were required to supplement with HRW or pure water five times during the training day (1,260 mL total). This included drinking 210 mL 30 min and 1 min before training, 210 mL between training sets, 210 mL immediately after training, and 420 mL 30 min into the recovery period. Participants performed half-squat exercises with the load set at 70% of one repetition maximum for six sets (half-squat exercise performed to repetitions failure each set). We measured the power output and number of repetitions in the free barbell half-squat used to assess muscular endurance performance in participants. The countermovement jump (CMJ) height, total quality recovery scale (TQRS), and muscle soreness visual analog scale (VAS) scores were measured to assess fatigue recovery status after training, as well as at 24 and 48 h of recovery. Results: The total power output (HRW: 50,866.7 ± 6,359.9W, Placebo: 46,431.0 ± 9,376.5W, p = 0.032) and the total number of repetitions (HRW:78.2 ± 9.5 repetitions, Placebo: 70.3 ± 9.5 repetitions, p = 0.019) in the H2 supplemented group were significantly higher than in the placebo group. However, there was no statistically significant difference (p< 0.05) between the H2 and placebo groups in CMJ, TQRS, and VAS. Conclusion: Eight days of intermittent HRW intake could significantly improve muscular endurance performance in trained individuals, making it a promising strategy for athletes or fitness enthusiasts looking to boost muscular endurance during resistance training or competitions. However, it should be noted that HRW intake alone may not be adequate to accelerate recovery from muscle soreness or fatigue following high-intensity training. [ABSTRACT FROM AUTHOR]

This study aimed to compare the acute inflammatory response following high-intensity eccentric exercise between resistance-trained young and master athletes with similar performance levels. Resistance-trained young (n=8; 22±2 years) and master (n=8; 52±4 years) male athletes of a similar performance level performed a standardized high-intensity eccentric squat exercise protocol (10 sets of half-squats at 70% of 1-repetition maximum). The serum concentration of 20 biomarkers related to tissue damage, inflammation, remodeling, and repair was measured at baseline, immediately after exercise, and over a 72 h recovery period. Both groups experienced similar muscle damage as evidenced by a comparable increase in creatine kinase activity 24 h after exercise (p<0.001). Interleukin-6 (p=0.009) and growth hormone (p<0.001) increased immediately post-exercise in both groups. Monocyte chemoattractant protein-1 increased immediately post-exercise only in young athletes (p=0.003) and then decreased 24 h later. There were no significant differences for the remaining variables, including cell markers related to neutrophil/macrophage activation or pro/anti-inflammatory cytokines. Resistance-trained young and master athletes, matched for performance level, showed an overall similar inflammatory response to eccentric exercise, possibly reflecting regulatory mechanisms or immunological adaptations to chronic stimulation in master athletes. [ABSTRACT FROM AUTHOR]

The prediction of one-repetition maximum (1RM) is highly relevant for strength and conditioning. The optimal minimum-velocity threshold (MVT) was recently proposed to increase the accuracy of 1RM predictions. Individual load-velocity profiles (LVP) were obtained in 18 athletes enrolled in recreational soccer. Reliability analyses were computed for all LVP-derived variables. Estimations of 1RM were made based on general (0.3 m.s− 1), pre-individual (mean velocity at 1RM obtained in a preliminary session) and optimal MVT (velocity that eliminates the difference between actual and predicted 1RM, determined in a preliminary session). The accuracy of 1RM predictions was examined using absolute-percent error and Bland-Altman plots. Between-day reliability of the LVP and 1RM was good (intraclass-correlation coefficients – ICCs>0.9 and coefficients of variation – CVs<5%). The individual and optimal MVT reached moderate-to-good reliability (ICCs>0.9 and CVs<10%, respectively). The predictions based on the optimal MVT displayed greater accuracy than those obtained with the individual and general MVT (absolute percent error: 2.8 vs. 5.5 vs. 4.9%, respectively). However, wide limits of agreement (LoA) were found between actual and estimated 1RM using this approach (~15 kg). Data indicate that the optimal MVT provides better estimations of 1RM for the free-weight back squat than the general and the individual MVT. [ABSTRACT FROM AUTHOR]

Objectives: Symptoms and motivation may impact adherence to home-based exercise training programs (HETP) during cancer treatment (CT) for lung or head and neck cancer. This study aimed to identify self-reported symptoms and their frequency, as well as motivation towards an HETP during CT for primary lung or head and neck cancer. Associations between symptoms and motivation with HETP adherence were also investigated. Methods: Participants underwent CT combined with an HETP that included aerobic (walk-based) and resistance training (Theraband®). Weekly assessment was conducted using a questionnaire developed by the researchers, evaluating the presence of symptoms. A scale (0 to 10) was used to assess motivation towards the HETP. Adherence was defined as the ratio between HETP sessions completed vs. the number prescribed. Symptom frequency was recorded as the number of weeks a symptom was experienced. Linear regression was used to explore associations. Results: Twenty-four participants were included (61 ± 7 yr; 21 males; head and neck cancer n = 18; median treatment duration: 9 [7 to 11] weeks). The most commonly reported symptoms were fatigue (33%), malaise (24%) and dysphagia (23%). Average score for motivation to exercise was 6.4 ± 2.0. Adherence to the HETP was 47%. Malaise was associated with reduced adherence to HETP (p = 0.002), explaining 35% of the variance. Motivation was associated with increased adherence (p = 0.008), explaining 28% of the variance. Conclusions: Fatigue, malaise and dysphagia were among the most frequently reported symptoms during treatment. Malaise and self-motivation to exercise can significantly influence adherence to HETPs. Symptom and motivational support might be necessary when implementing HETPs during CT. [ABSTRACT FROM AUTHOR]

Research examining the changes in muscle oxygen saturation across multiple sets of resistance exercise is limited. The purpose of this study was to describe the physiological response of muscle oxygenation parameters during upper-body resistance exercise and examine the differential effects of relevant participant characteristics on resistance training performance and muscle oxygen saturation dynamics. Sixty-one recreationally trained men (n = 44; 21.8 ± 2.6 years) and women (n = 17; 20.2 ± 1.8 years) completed five-repetition maximum sets of barbell bench presses at a load equal to 75% 1-RM with a 2 min rest interval. Muscle oxygen saturation (SmO2) dynamics within the anterior deltoid were monitored using a portable near-infrared spectroscopy sensor. The percent change in SmO2 (∆%SmO2), the muscle oxygen re-saturation rate (SmO2RecSlope), and the highest measured SmO2 value during recovery periods (SmO2Peak) were measured. Two-way (sex [men, women] x time [sets 1–5]) repeated measures analyses of variance (ANOVA) were performed on muscle saturation variables. To examine the effect of relevant controlling variables, separate analyses of covariance (ANCOVA) with repeated measures were also performed. No differences were seen with ∆%SmO2 across sets. The main effects for sets occurred for SmO2RecSlope, whereby a decline was noted on sets 4 and 5 (p = 0.001) compared to set 1. Additionally, SmO2Peak was the lowest on set 5 (p < 0.001) compared to all other sets. Moreover, body mass (p = 0.013), diastolic blood pressure (p = 0.044), and mean arterial pressure (p = 0.033) for ∆%SmO2 were the only significant covariates noted amongst the muscle oxygenation variables. In conclusion, no sex differences and only a few set differences in muscle oxygen saturation dynamics were seen without employing any covariates. Body mass, diastolic blood pressure, and mean arterial pressure were identified as factors that could influence observed responses. [ABSTRACT FROM AUTHOR]

Objective To construct a resistance band exercise training program through literature re- view and Delphi expert consultation method, and to evaluate its effects on glycemic and bone density indicators in patients with type 2 diabetes complicated with osteoporosis. Methods A total of 81 middle-aged and elderly patients admitted to the department of endocrine osteoporosis in Jiangxi Provincial People's Hospital/First Affiliated Hospital of Nanchang Medical University from April to August 2023 as the research subjects. They were divided into the observation group and the control group using the random number table method. The observation group was given a 3-month resistance band exercise training program in addition to routine treatment and nursing, while the control group was given routine treatment and nursing measures. The glycemic and bone density indicators of the two groups were compared. Results A total of 74 patients completed the study, including 36 in the observation group and 38 in the control group. The fasting blood glucose. postprandial 2-hour blood glucose, and hemoglobin Alc of the observation group were lower than those of the control group, and the differences were statistically significant (P<0.05); the number of compliance targets achieved by the two groups were compared, and the difference was statistically significant (P<0.01); the bone density of the two groups after intervention was compared, and there was no statistically significant difference (P>0.05). Conclusion The resistance band exercise training program can not only reduce the glycemic indicators of patients, but also effectively improve their compliance with exercise, but the effect on improving the patient s bone mineral density is not obvious. [ABSTRACT FROM AUTHOR]

Background: Resistance training is hardly recommended for postmenopausal women to counteract negative effects of hormonal changes. However, some concern exists about the marked hemodynamic responses caused by high-load resistance exercises. In this regard, studies on young, healthy, physically active individuals suggest that set configuration can modulate acute cardiovascular, metabolic, and cardiac autonomic responses caused by resistance training sessions, but this has not yet been explored in postmenopausal women. Methods: A sample of 60 physically active postmenopausal women (30 normotensive, 30 hypertensive) will participate in this crossover study. After a medical exam, ergometry, familiarization session, and two testing sessions, participants will complete three experimental sessions and one control session in a randomized order. Each experimental session includes 36 repetitions of four exercises (horizontal leg press, bench press, prone leg curl, and lat pull-down) differing in set configuration: 9 sets of 4 repetitions (i.e., 33% intensity of effort) with 45 s of inter-set recovery, 6 sets of 6 repetitions (50% intensity of effort) with 72 s, and 4 sets of 9 repetitions (75% intensity of effort) with 120 s; with 4 min rest between exercises. Before and immediately after each session, arterial stiffness, hemodynamic variables, cardiac autonomic modulation, baroreflex sensitivity, sympathetic vasomotor tone, and resting oxygen uptake will be evaluated. Furthermore, perceived effort, mechanical performance (e.g., power, velocity), heart rate, and lactatemia will be collected throughout sessions. The impact of set configuration on these variables will be analyzed, along with comparisons between normotensive and hypertensive women. Discussion: Cardiovascular responses to resistance exercise have been scarcely studied in females, particularly postmenopausal women. The results of this study will provide information about the modulating role of set structure on metabolic and cardiovascular responses of normotensive and hypertensive postmenopausal women to resistance training. Clinical trial registration: NCT05544357 on 7 December 2022. [ABSTRACT FROM AUTHOR]

Calisthenics is a form of bodyweight exercise that involves dynamic and rhythmic exercises. The physiological responses during and after calisthenics remain unclear. This study examined whether a bout of full-body calisthenics, a form of circuit resistance exercise that involves bodyweight movements, yields greater excess post-exercise oxygen consumption (EPOC) than steady-state exercise (SSE) at matched oxygen consumption. Twenty-two young adults (age = 22.1 ± 2.4 years; four females) participated in two separate, oxygen consumption (${\dot{\rm V}}$V˙O2) matched exercise sessions: full-body calisthenics (nine body weight exercises, 15 reps × 4 sets) and SSE (running on a treadmill at 60–90% of ${\dot{\rm V}}$V˙O2max). Energy expenditure, substrate utilization, and EPOC were measured during exercise and 60 min of recovery. SSE showed higher peak ${\dot{\rm V}}$V˙O2 and heart rate during exercise than those during calisthenics. However, the post-exercise ${\dot{\rm V}}$V˙O2 and energy expenditure above baseline level during the first 10 min of recovery were significantly higher with calisthenics than with SSE (0–5 min: 1.7 ± 0.5 vs. 1.0 ± 0.6; 6–10 min: 0.5 ± 0.4 vs. 0.1 ± 0.2 kcal/min; 31–60 min recovery: −0.1 ± 0.3 vs. −0.2 ± 0.2; all p < .05). During calisthenics, participants utilized a significantly higher proportion of energy from carbohydrates (85 vs. 73%; p < .01) but after exercise, they used a greater proportion of fat as the energy source (71 vs. 50%; p < .01) compared to SSE. Full-body calisthenics, a circuit-style bodyweight exercise, may be more effective than ${\dot{\rm V}}$V˙O2 matched SSE in triggering greater EPOC and fat metabolism. Further efforts are warranted to demonstrate whether different amounts of skeletal muscle mass groups indeed lead to varying EPOC responses and energy use. [ABSTRACT FROM AUTHOR]

We compared the effects of varied and constant resistance exercises on muscular adaptations in young women. Seventy young women (21.8 ± 3.4 yrs, 62.0 ± 12.3 kg, 162.3 ± 5.7 cm) were randomly divided into two groups: constant resistance exercises (CON-RE, n = 38) or varied resistance exercises (VAR-RE, n = 32). The resistance training (RT) was performed thrice a week over 10 weeks. CON-RE performed a 45º leg press and stiff-leg deadlift in every training session, while VAR-RE performed 45º leg press and stiff-leg deadlift in the first training session of the week, hack squat and prone leg curl in the second, and Smith machine squat and seated-leg curl in the third. Both groups performed two sets of 10–15 repetitions maximum per resistance exercise. We measured the muscle thickness of the thigh’s anterior, lateral, and posterior aspects by ultrasonography at different muscle sites (proximo-distal). Muscular strength was analyzed from the one-repetition maximum (1RM) tests in the 45° leg press and leg extension (non-trained exercise). The muscle thickness increased similarly in both groups for all muscles and sites (CON-RE: +7.8–17.7% vs. VAR-RE: +7.5–19.3%, p > .05). The 1RM increased similarly in both groups (CON-RE: +24.4–32.1% vs. VAR-RE: +29.0–30.1%, p > .05). Both RT routines resulted in virtually similar muscular strength gains and hypertrophy. Therefore, both strategies should be considered for the improvement of strength and muscle growth. [ABSTRACT FROM AUTHOR]

Background: Fibromyalgia (FM) is characterized by widespread chronic pain. Although pain is the main symptom, approximately 90% of patients have depression. This study aimed to analyze the effects of Resistance Training (RT) with low and high intensity on depression in patients with FM. Methods: Thirty-eight women with FM and 31 healthy women were allocated to the low-intensity, high-intensity, preferred-intensity, and control groups. The patients underwent 8 weeks of supervised RT, with two sessions per week of approximately 1 h. The low-intensity resistance training group (LIRT) performed two sets of 12 maximum repetitions. The high-intensity resistance training group (HIRT) performed four sets with six maximum repetitions, and the preferred intensity group (PI) performed three sets, with eight to 12 repetitions, according to the patient's tolerance. The healthy control group did not perform any type of exercise. Depression was assessed using the Beck depression inventory before the start of the intervention, after 4 and 8 weeks. Results: FM patients have higher levels of depression than women without the disease. After 4 weeks, there was a difference in depressive symptoms between the HIRT and LIRT (p = 0.048), and the PI and LIRT (p = 0.048). Conclusion: Prescribing RT with low or high intensity did not significantly reduce depression in patients with FM after 8 weeks, however, analyses between groups after 4 weeks indicated that low-intensity training is more effective than high-intensity training. The prescription of RT exercise to FM could vary among low, high, and preferred intensity, following the patient's tolerance for pain. [ABSTRACT FROM AUTHOR]

Objective: This study was to investigate the developmental characteristics of executive function (EF) in obese adolescents and the time-course effects of a 14-week exercise intervention combining aerobic exercise and resistance training on EF in this population. Methods: The experimental group of 28 obese junior high school students participated in the exercise intervention combining aerobic exercise and resistance training, while the control group of 24 healthy weight junior high school students engaged in the regular recess exercise. EF, including inhibition, working memory, and cognitive flexibility, was assessed 1 week prior to the exercise intervention and at 12 and 14 weeks post-intervention. Changes in EF sub-functions in both groups at different time points during the exercise intervention were analyzed. Results: The findings revealed that obese junior high school students exhibited lower levels of inhibition (p = 0.003, Cohen's d = 0.848) and cognitive flexibility (p = 0.013, Cohen's d = 0.706) compared to their healthy weight peers. The exercise intervention combining aerobic exercise and resistance training led to significant improvements in EF among obese junior high school students, with inhibition (p < 0.01, Cohen's d = 0.713; p = 0.003, Cohen's d = 0.683) and cognitive flexibility (p = 0.001, Cohen's d = 0.797; p < 0.01, Cohen's d = 0.890) showing significant improvement at 12 and 14 weeks post-intervention, and working memory demonstrating significant improvement at 14 weeks (p = 0.004, Cohen's d = 0.710). No significant differences were observed in EF over time in healthy weight junior high school students. Conclusion: Obese adolescents had impaired EF, as evidenced by low levels of the inhibition and cognitive flexibility compared to healthy weight adolescents. The exercise intervention combining aerobic exercise and resistance training had a positive effect on EF of obese adolescents. The time-course effects of the intervention on improvements in inhibition, working memory, and cognitive flexibility varied with intervention duration in obese adolescents, with significant changes in inhibition and cognitive flexibility observed at 12 weeks and significant changes in working memory at 14 weeks. [ABSTRACT FROM AUTHOR]

Introduction: Physical inactivity and sedentary behavior both increase the risk of chronic disease and mortality. Regular participation in physical activity and reducing sedentary behavior play important roles in maintaining physical health and disease prevention. Objective: The purpose of this study was to investigate the effect of programed walking exercise using a wearable hip exoskeleton, Bot Fit on muscle strength, muscle effort, and the kinematics of the pelvis in younger adults. Methods: We designed three parallel experimental conditions and randomly assigned participants to one of three groups: those assigned to exercise using an interval program of Bot Fit (interval group), those who used a power program of Bot Fit (power group), and a control group who exercised without Bot Fit. A total of 45 young adults participated in 18 exercise-intervention sessions over six weeks, and all participants were assessed at two time points: before and after the 18 exercise sessions. Each assessment evaluated muscle strength, muscle effort, and the kinematics of the pelvis during walking. In addition, the number of steps, distance, energy expenditure, and heart rate for 30 min during the exercise sessions were recorded. Results: A significant increase in the maximum voluntary contraction (MVC) of the left biceps femoris (BF) was evident in the interval group, while significant changes in the MVC of the bilateral BF were seen in the power group after Bot Fit exercise. A significant decrease of muscle effort in the right BF in the interval group and right lumbar erector spinae and bilateral BF in the power group were also observed. In addition, the symmetry index of pelvic tilt significantly improved in the interval group, and greater exercise volume and intensity in both the interval and power groups compared with the control group were confirmed as measured by the number of steps, distance, energy expenditure, and heart rate. Conclusions: The results of this study confirmed the beneficial effect of programed walking exercise using the Bot Fit on muscle strength of trunk and lower extremities, muscle effort, and pelvic movement symmetry in younger adults. Personalized exercise programs can be provided for younger adults using various resistance or assistance modes of robotic device with the Bot Fit. Trial Registration: ClinicalTrials.gov, NCT05862077. Registered 22 March 2022, https://register.clinicaltrials.gov/. Key Points: • Bot Fit exercise offers several key advantages over exercise without a Bot Fit in terms of muscle strength, muscle effort, and pelvic symmetry during walking in younger adults. • Greater exercise volume and intensity in interval and power groups who exercised with Bot Fit were confirmed through number of steps, distance, energy expenditure, and heart rate compared to control group who exercised without Bot Fit. [ABSTRACT FROM AUTHOR]

The aim of this study was to analyze the effects of different exercise interventions involving chronic exercise (endurance and strength groups) carried out in physical education on physical fitness and cognitive functions. A group of 72 adolescent students from the city of Melilla (Spain) aged between 13 and 17 years old (M = 15.38, SD = 0.78) participated in the current study. A D2 attention test was used in order to analyze selective attention and concentration. Physical fitness was measured through the ALPHA-Fitness battery. The analysis taken indicated a significant relationship between physical fitness level, attention and concentration. Moreover, the intervention resulted in significant reductions in body weight and waist circumference in the resistance and strength groups compared to the control group, indicating positive effects on body composition. All the groups demonstrated enhanced aerobic capacity, as evidenced by improvements in VO2 max after the intervention period. Furthermore, significant enhancements in most attentional measures (TR, TA, O, C, TOT, CON and TR−) were observed across all the groups, with an additional temporary improvement in TR+ for the strength group. Our findings suggest that an 8-week school-based exercise intervention, regardless of specific exercise type (resistance or strength), can positively impact body composition, aerobic capacity and attention in adolescents. These results emphasize the importance of integrating physical activity programs into school environments to promote holistic health and well-being in this population. Future research should focus on elucidating the underlying mechanisms of these effects and exploring the long-term benefits of such interventions. [ABSTRACT FROM AUTHOR]

The objectives of this study were to compare the effects of two in-season velocity loss training methods (VBT) on performance outcomes and to evaluate the effects of velocity-based training compared to traditional resistance training (TRT) on performance outcomes in young elite soccer players. VBT utilized the same relative load but varied in the extent of velocity loss during the set: 15% (VL15%) and 30% (VL30%). Thirty-four players were recruited and randomly distributed into three groups: the VL15% group (n = 12; age = 18.50 ± 0.67 years; stature = 183.41 ± 4.25 cm; body mass = 75.08 ± 5.57 kg), the VL30% group (n = 11; age = 17.91 ± 0.60 years; stature = 181.21 ± 6.56 cm, body mass = 73.58 ± 6.22 kg), and the traditional strength training group TRT (n = 11; age = 18.14 ± 0.74 years; stature = 182.17 ± 5.52 cm; body mass = 74.86 ± 6.68 kg). Alongside regular soccer sessions and matches, the groups underwent a four-week (2 sesions per week) resistance training intervention with back squats involved. Changes in leg strength (SQ1RM), 20 m sprint time (SPR 20 m), countermovement jump height (CMJ), reactive strength index (RSI), and change of direction (COD) from before and after were evaluated using a 3 × 2 ANOVA. While no significant interaction was found for SQ1RM and SPR20, all of the groups showed significant pre to post improvements. Significant interactions were observed for CMJ (F = 38.24, p = 0.000), RSI (F = 8.33; p = 0.001), and change of direction agility test (COD) (F = 3.64; p = 0.038), with a post hoc analysis showing differences between the VL15 (6.0%) and TRT (1.7%) groups (p = 0.034); VL15 (12.2%) and VL30 (3.2%) groups (p = 0.004); VL15 and TRT (0.4%) (p = 0.018); VL15 (2.4%) and VL30 (1.5%) (p = 0.049); and between the VL15 and TRT (0.4%) groups (p = 0.015). Four weeks of VL15% training during the season induced similar strength increases to VL30% and TRT, superior improvements in RSI and COD compared to VL30%, and superior improvements in CMJ, RSI, and COD tests compared to TRT. Thus, incorporating the VL15% training method may be recommended to improve power-related performance metrics in elite young soccer players. [ABSTRACT FROM AUTHOR]

Introduction: Systematic reviews and meta-analyses point to the benefits of physical exercise for adolescents with cerebral palsy, improving physical conditioning, muscle strength, balance, and walking speed. However, given the high number of reviews that include randomized and non-randomized studies, it is increasingly necessary to assess the methodological quality of these reviews. This scoping review investigated the methodological quality of systematic reviews and meta-analyses on the effects of physical exercise in adolescents with cerebral palsy to elucidate the methodological limitations of the research and the priorities to be observed in future research. Method: The electronic search used PubMed, Web of Science, and Cochrane. Studies published between 2016 and 2023 were selected. The terms used were "cerebral palsy" combined with "physical fitness", "exercise", and "physical activity". Results: A total of 219 original reviews were selected. Of these, 19 reviews were included for data analysis. AMSTAR2 was used to assess the methodological quality of the reviews. Three reviews presented high methodological quality (15.78%) and three had moderate methodological quality (15.78%). The remaining reviews had low or critically low methodological quality, according to AMSTAR2. Interpretation: This study evidenced that systematic reviews have variable methodological quality and that new studies are still needed. [ABSTRACT FROM AUTHOR]

AbstractContext:Objective:Results:Conclusions: Energy homeostasis is a primary factor for the survival of mammals. Many tissues and organs, among which is the liver, keep this homeostasis in varied circumstances, including caloric restriction (CR) and physical activity.This study investigated glucose metabolism using the following groups of eight-week-old male Swiss mice: CS, sedentary and fed freely; RS, sedentary and RT, trained, both under 30% CR (n = 20–23 per group).Organs and fat depots of groups RS and RT were similar to CS, although body weight was lower. CR did not impair training performance nor affected systemic or hepatic glucose metabolism. Training combined with CR (group RT) improved in vivo glucose tolerance and did not affect liver gluconeogenesis.The mice tolerated the prolonged moderate CR without impairment of their well-being, glucose homeostasis, and resistance training performance. But the higher liver gluconeogenic efficiency previously demonstrated using this training protocol in mice was not evidenced under CR. [ABSTRACT FROM AUTHOR]

Key points Testosterone, the major androgen, influences the reproductive and non‐reproductive systems in males and females via binding to the androgen receptor (AR). Both circulating endogenous testosterone and muscle AR protein content are positively associated with muscle mass and strength in males, but there is no such evidence in females. Here, we tested whether circulating testosterone levels were associated with muscle mass, function, or the muscle anabolic response to resistance training in pre‐menopausal females. Twenty‐seven pre‐menopausal, untrained females (aged 23.5 ± 4.8 years) underwent a 12‐week resistance training programme. Muscle strength, size, power, and plasma and urine androgen hormone levels were measured. Skeletal muscle biopsies were collected before and after the training programme to quantify the effect of resistance training on AR content and nuclear localisation. Primary muscle cell lines were cultured from a subset (n = 6) of the participants’ biopsies and treated with testosterone to investigate its effect on myotube diameter, markers of muscle protein synthesis and AR cellular localisation. Physiological levels of total testosterone were not associated with muscle mass or strength at baseline or with the changes in muscle mass and strength that occurred in response to resistance training in our cohort of pre‐menopausal females. In contrast, bioavailable testosterone and the proportion of nuclear‐localised AR were positively associated with skeletal muscle mass and strength in pre‐menopausal females. In vitro, supra‐physiological doses of testosterone increased myocyte diameter, but this did not occur via the Akt/mTOR pathway as previously suggested. Instead, we show a marked increase in AR nuclear localisation with testosterone administration in vitro. Total circulating testosterone was not related to muscle mass or strength before or after resistance training in pre‐menopausal females. Bioavailable testosterone was positively related to exercise‐induced muscle hypertrophy in pre‐menopausal females. In vivo nuclear localisation of the androgen receptor was positively related to muscle mass in pre‐menopausal females at baseline, but not to resistance training‐induced hypertrophy. Testosterone treatment induced androgen receptor nuclear translocation but did not induce mTOR signalling in primary skeletal myocytes cultured from pre‐menopausal female muscle. [ABSTRACT FROM AUTHOR]

Background: Patellar tendinopathy (PT) is a common sport injury prone to recurrence. Heavy Slow Resistance Training (HSR) and High-Dose Therapeutic Ultrasound (TUS) are frequently used interventions for PT. However, the combined effectiveness of these therapies remains unclear. This study investigated the impact of combination therapy on functional outcomes in patients with PT. Methods: Fifty-one college students aged 18–25, diagnosed with PT via musculoskeletal ultrasound, were randomly assigned to one of three groups (n = 17 per group): combined HSR and high-dose TUS, HSR training alone, or high-dose TUS alone. The eight-week intervention included assessments using the Victorian Institute of Sport Assessment-Patella (VISA-P), Visual Analogue Scale (VAS), Y-balance Test (YBT), Modified Thomas Test (MTT), Horizontal Jumping Distance, Maximum Isometric Muscle Strength Test, and musculoskeletal ultrasound for patellar tendon thickness and blood flow. Assessments were conducted at baseline and post-intervention, with a follow-up VISA-P assessment at week 16. This randomized, single-blind controlled trial was registered on ISRCTN11447397 (www.ISRCTN.com) on February 17, 2024 (retrospectively registered). Results: All groups demonstrated significant improvements in VISA-P scores at the end of the intervention compared to baseline (p < 0.01), with the combined group showing the greatest improvement (21 points). Follow-up at week 16 revealed continued improvement in VISA-P scores for the combined and HSR groups, while the TUS group showed a slight decrease (from 74 to 70). All groups displayed significantly reduced VAS scores post-intervention (p < 0.01) compared to baseline, indicating decreased pain. While no significant between-group differences were observed in pre-intervention VAS scores, post-intervention results revealed significant differences between the combined and HSR groups (p < 0.05), as well as between the combined and TUS groups (p < 0.01). Conclusion: Both exercise intervention and high-dose TUS appear effective in reducing pain and improving motor function in individuals with PT. However, the therapeutic effect of high-dose TUS alone seems limited compared to exercise intervention. The combined application of both methods yielded the most significant improvements in pain relief and motor function enhancement. [ABSTRACT FROM AUTHOR]

Background: Sprinting is important for both individual and team sports, and enhancing performance is often done through resisted, assisted, or combined sprint training. However, the effectiveness of these methods compared to traditional sprint training remains inconclusive. The objective of this review with meta-analysis was to review the current literature on intervention studies analyzing the effects of resisted, assisted, and combined (resisted–assisted) training on sprint kinematics and performance in terms of acceleration and maximum velocity. Methods: A literature search was conducted using SPORTDiscus up to and including April 19, 2023. The following eligibility criteria were applied: (1) a longitudinal study over a minimum of four weeks; (2) studies using resistance (sleds, parachutes, uphill slope, towing devices) or assistance (towing devices, downhill slope), or a combination of both; (3) a main intervention focused on resisted or assisted training, or a combination of both; (4) measurement of maximum velocity, acceleration measured in (s) with a minimum distance of 10-m, or kinematic changes such as step frequency, ground contact time, flight time, and step length; and (5) peer-reviewed studies. Results: Twenty-one studies were included in this review with meta-analysis. Kinematic changes, changes in acceleration, and changes in maximum velocity were analyzed. Only resisted sprint training was associated with a significant improvement in 10-m acceleration compared to normal (i.e. without assistance or resistance) sprinting (Z = 2.01, P = 0.04). With resisted, assisted and combined sprint training no significant changes in kinematics, 20-m times or maximum velocity were found when compared to normal sprint training. However, in the within group, effect sizes resisted sprint training had a moderate effect on 10-m times. A moderate effect on ground contact time, step frequency, 10-and 20-meter time after assisted sprint training was found, while combined sprint training had a moderate effect on maximum velocity. Conclusion: Resisted sprint training seems to be effective for improving acceleration ability, with significant decreases in the 10-m times. There were no other significant findings, suggesting that normal sprinting yields the same change in 20-m times, kinematics and maximum velocity as resisted, assisted and combined sprint training. However, moderate effect sizes using these different training methods were found, which may suggest that the different training forms could be useful for improving different parts of the sprint and changing the kinematics. Combination (uphill–downhill) sprint training seems to be effective at improving maximum velocity, while assisted sprint training was the most effective training to increase step frequency, which can affect sprint performance positively. However, more studies, especially in assisted sprints, need to be conducted to determine the full effect of these training forms. Key Points: • Resisted sprint training is effective for improving acceleration ability; however, combination (uphill–downhill) sprint training is more effective at improving maximum velocity. • The overall group analysis shows that all of the training forms decrease the flight time. • Assisted sprint training is the most effective training to increase step frequency, which can affect sprint performance positively. [ABSTRACT FROM AUTHOR]

ABSTRACT Background Methods Results Conclusions Chemotherapy‐induced peripheral neuropathy (CIPN) is a common and dose‐limiting chemotoxicity caused by oxaliplatin. This study investigated the relationship between dietary quality and the development of moderate and/or severe CIPN in colon cancer survivors using data from the Focus on Reducing Dose‐Limiting Toxicities in Colon Cancer with Resistance Exercise trial (ClinicalTrials.gov identifier NCT03291951).Diet quality was collected using a 127‐item food‐frequency questionnaire and was scored using the Alternative Healthy Eating Index‐2010 (AHEI‐2010). CIPN was assessed with the Patient‐Reported Outcomes version of the Common Terminology Criteria for Adverse Events at each chemotherapy cycle. The association of dietary quality with time to the first moderate‐to‐severe (moderate‐severe) or severe event of CIPN was estimated using Cox proportional hazards models. Only participants who received oxaliplatin were included in this analysis (n = 132).Seventy‐four participants (56.1%) reported moderate‐severe CIPN. Higher dietary quality was associated with a significantly decreased risk of moderate‐severe CIPN (hazard ratio [HR], 0.96; 95% confidence interval [CI], 0.93–0.99) and severe CIPN (HR, 0.91; 95% CI, 0.85–0.98). Consumption of red and processed meat (HR, 1.78; 95% CI, 1.07–2.83) and sugar‐sweetened beverages (HR, 1.33; 95% CI, 1.10–1.59) was associated with an increased risk of moderate‐severe CIPN. Consumption of sugar‐sweetened beverages also was associated with an increased risk of severe CIPN (HR, 1.57; 95% CI, 1.14–2.18), whereas vegetable consumption was associated with a reduced risk of severe CIPN (HR, 0.29; 95% CI, 0.09–0.73).Among patients with colon cancer who received oxaliplatin‐based chemotherapy, higher baseline dietary quality was associated with a reduced risk of moderate‐severe CIPN. [ABSTRACT FROM AUTHOR]

Objective: Research evidence suggests that exercise is a potent therapeutic strategy for non-alcoholic fatty liver disease (NAFLD). Many investigations have delved into the curative potential of diverse exercise regimens on NAFLD. This investigation synthesizes findings from randomized controlled trials via a network meta-analysis to evaluate the efficacy of exercise-based interventions on NAFLD. Methods: We conducted a search across five electronic databases (Web of Science, EMBASE, PubMed, SCOPUS, and CNKI)to identify randomized controlled trials (RCTs) comparing the effects of different exercise modalities on metabolic profiles and liver functions in patients with NAFLD. The literature search was comprehensive up to 15, December 2023. The selected studies were subjected to a rigorous quality appraisal and risk of bias analysis in accordance with the Cochrane Handbook's guidelines, version 5.1.0. We employed Stata/MP 17 for the network meta-analysis, presenting effect sizes as standardized mean differences (SMD). Results: This study aggregated results from 28 studies, involving a total of 1,606 participants. The network meta-analysis revealed that aerobic exercise was the most effective intervention for improving BMI in patients with NAFLD, demonstrating a significant decrease in BMI (-0.72, 95%CI: -0.98 to -0.46; p < 0.05; Surface Under the Cumulative Ranking (SUCRA) = 79.8%). HIIT was the top intervention for enhancing HDL-C (0.12, 95% CI: 0.04 to 0.20; p < 0.05; SUCRA = 76.1%). Resistance exercise was the most effective for reducing LDL-C (-0.20, 95% CI: -0.33 to -0.06; p < 0.05; SUCRA = 69.7%). Mind-body exercise showed superior effectiveness in improving TC (-0.67, 95% CI: -1.10 to -0.24; p < 0.05; SUCRA = 89.7%), TG = -0.67, 95% CI: -1.10 to -0.24; p < 0.05; SUCRA = 99.6%), AST (-8.07, 95% CI: -12.88 to -3.25; p < 0.05; SUCRA = 76.1%), ALT (-12.56, 95% CI: -17.54 to -7.58; p < 0.05; SUCRA = 99.5%), and GGT (-13.77, 95% CI: -22.00 to -5.54; p < 0.05; SUCRA = 81.8%). Conclusion: This network meta-analysis demonstrates that exercise interventions positively affect various metabolic profiles and liver functions in NAFLD patients. Mind-body exercises are particularly effective, surpassing other exercise forms in improving metabolic profiles and liver functions. [ABSTRACT FROM AUTHOR]

This study aimed to describe the gender roles of people interested in an exercise program done on outdoor exercise structures and test if gender roles were associated with studied outcomes. Older adults aged 65+ who were not currently performing resistance training were invited to participate. Gender roles were quantified using the Bem Sex Role Inventory 30-item questionnaire (−60 [feminine] to +60 [masculine]). Outcomes included completing the 6-week intervention (Y/N) and changes in physical function (one leg stance, 30-s chair stand), strength (predicted maximal chest press and leg press, grip strength), power (knee extensor power), and overall health via the SF-36 questionnaire. Twenty-nine adults (65.5% female; median 72 years old) participated in the study, and 17 completed the intervention (58.6%). The median (interquartile) gender role score was −13.0 (−19.5 to −8.5), with no gender role difference (p =.62) between completers and non-completers. These results suggest that older adults interested in such a program portray themselves as more feminine. No association was found between gender role scores and changes in any study outcomes. In this setting, gender roles did not seem to impact the study outcomes and therefore may not need to be considered when designing an outdoor exercise structure program. [ABSTRACT FROM AUTHOR]

Understanding muscle activation during exercises is crucial for devising effective training programs. We examined correlations between self-reported and electromyographic (EMG) muscle activity during upper-body exercises performed at loads corresponding to 4-6 repetition maximums (RMs). Thirteen male sub-elite soccer players who had previously engaged in resistance training participated in two testing sessions. In the initial session, the loads corresponding to 4–6 repetitions were determined for six exercises: Lat Pull Down (LPD), Barbell Bent Over Row (BBOR), Dumbbell Row (DR), Barbell Pull Over (BPO), Dumbbell Reverse Fly (DRF), and Dumbbell Concentration Curl (DCC). At post-exercise, participants rated their perceived muscle activation for three targeted muscles in each exercise on a 1–10 point Likert scale (LS). In the subsequent session, we used EMG to measure the activity of eight agonist and synergist muscles during these exercises. We found that one of two synergist muscles consistently demonstrated higher activity levels. Interestingly, we observed no difference in activity between primary and secondary (or synergist) muscles across all exercises. Most importantly, we found no significant correlation between the perceived muscle activation rate and the EMG measured activation level for any exercise. In conclusion, our findings suggest that, despite differential muscle activity during specific exercises, self-reported muscle activation may not accurately correspond to actual muscle activation, as measured via EMG, due to the participants' poor interoceptive awareness of muscles. These data highlight the potential limitations of relying on perceived muscle activation as a sole gauge of training intensity. [ABSTRACT FROM AUTHOR]

Background Exercise referral schemes (ERS) are an effective strategy for increasing physical activity (PA) in older adults. Behavioural self-management strategies (SMS) may augment the maintenance of PA and associated benefits in this population, resulting in preservation of the functional capacity and prevention of disability over the long-term. Aim The primary aim was to investigate the long-term (22-months) effects of ERS enhanced with SMS on functional capacity assessed by the Short Physical Performance Battery (SPPB) compared to ERS (primary comparison) and a control condition (CTRL). Secondarily, between-group effects after 4 and 16 months on the SPPB and self-reported disability outcomes were investigated. Methods 1360 physically inactive community-dwelling older adults ≥65 years from four European countries were randomized into (i) 16 weeks ERS enhanced with SMS (ERS-SMS), (ii) ERS alone and (iii) CTRL. In addition to SPPB, self-reported function and disability were assessed by the short-form late life function and disability index and with a six-item activity of daily living questionnaire. Results No long-term effects were found for the SPPB-score in ERS-SMS vs ERS (0.21 point, 95% CI [−0.04, 0.46]). Significant group × time effects were observed for the SPPB-score after 4 months in favour of ERS-SMS over CTRL (0.51 point, 95% CI [0.29, 0.73]) and ERS (0.46 point, 95% CI [0.24, 0.68]). Conclusion The study did demonstrate differences, in favour of ERS + SMS, but on SPPB these were small, and not sustained over time. The additional effect of SMS was inconsistent and uncertain. [ABSTRACT FROM AUTHOR]

Objectives We assessed the effects of different exercise modalities and doses on depression levels in older adults. Methods Systematic searches of the PubMed, Web of Science, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Scopus databases were conducted from the start of database construction until December 2023. Studies were included if they were randomised controlled trials (RCTs) of exercise interventions in older adults. Pairwise, network and dose-network meta-analyses were conducted using random-effects models for the outcome of depression in older adults. Results A total of 80 RCTs with 5536 participants were included in this study. Network meta-analyses showed that resistance exercise [standardized mean difference (SMD) = − 0.68, 95% confidence interval (CI): − 0.90, − 0.46] and mind–body exercise (MBE; SMD = − 0.54, 95% CI: − 0.72, − 0.37) were the most effective forms of exercise for improving depression in older adults, followed by aerobic exercise (SMD = − 0.31, 95% CI: − 0.50, − 0.13) and mixed exercise (SMD = − 0.23, 95% CI: − 44, − 0.01). In addition, a U-shaped dose–response relationship was found between overall exercise dose and depression levels in older adults, and a significant response was seen after 390 metabolic equivalent (MET)-min/week. Conclusions Our study determined the effectiveness of different exercises in improving levels of older adults and found that resistance exercise and MBE were more effective adjunctive treatments. By providing the most effective treatments, older adults can reap the benefits of improving depression in older adults at doses lower than the World Health Organization guidelines. [ABSTRACT FROM AUTHOR]

This study aimed to investigate the acute effects of resistance exercise on muscle architecture and tissue organization at rest and during isometric maximum voluntary contraction (iMVC) of the gastrocnemius medialis muscle. In 16 healthy adults (25 ± 3 y), ultrasound scans were captured before (pre), immediately after (post), and 15 min after (post_15) single-leg calf raises during rest and iMVCs. Measurements included muscle thickness (MT), pennation angle (PA), and fascicle length (FL). Spatial frequency analysis (SFA) assessed tissue organization (e.g. peak spatial frequency radius (PSFR), quality factor (Q6)). MT increased significantly from pre to post (+5.7%) and post_15 (+5.6%) at rest. During iMVC, MT and FL increased significantly from pre to post (MT: +8.1%, FL: +14.9%) and post_15 (MT: +5.2%, FL: +10.5%), while PA decreased significantly from pre to post_15 (−10.2%). PSFR and Q6 decreased significantly from pre to post (−7.0-8.2%) and increased from post to post_15 (+10.3-10.6%) at rest, with no significant changes during iMVC. Resistance exercise led to altered muscle architecture for more than 15 min, while SFA parameters reverted to baseline within 15 min. Thus, SFA potentially enables early differentiation of potential physiological alterations in muscle micro-morphology. [ABSTRACT FROM AUTHOR]

Sedentary lifestyles reduce muscle mass, strength, power, and alter viscoelastic properties. Plyometric jump training (PJT) shows promise in countering these effects, but the optimal training volume for individuals with low athletic performance remains unclear. This study aimed to determine the minimal PJT volume required to improve muscle and tendon viscoelastic properties, strength, and power in sedentary individuals. A double-blind randomised controlled trial included 44 participants divided into three groups: Control Group (CG) (n = 16), Reduced Volume Training Group (RVTG) (n = 16), and Training Group (TG) (n = 12). The four-week PJT programme involved three weekly sessions with gradual volume increments; RVTG performed 50% less volume than TG. Baseline and follow-up assessments included the isokinetic standing up (SU) and sitting down (SD) phases at 15 cm/s and 5 cm/s, and myotonometer measurements. In the SU phase at 15 cm/s, significant differences were found (p = 0.01) with higher values in TG (10.0 ± 3.3 N/kg) compared to CG and RVTG. At 5 cm/s, differences in SD were observed (p = 0.002). For Achilles tendon properties in RVTG: stiffness (p = 0.04), decrement (p = 0.01), and relaxation (p = 0.02). A PJT volume of 2,414 jumps improved muscle strength, while 1,207 jumps altered tendon properties. [ABSTRACT FROM AUTHOR]