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1,015 results on '"Ritieni, Alberto"'

103. Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study

Author

Castaldo, Luigi, Laguzzi, Federica, Strawbridge, Rona J., Baldassarre, Damiano, Veglia, Fabrizio, Vigo, Lorenzo, Tremoli, Elena, de Faire, Ulf, Eriksson, Per, Smit, Andries J., Aubrecht, Jiri, Leander, Karin, Pirro, Matteo, Giral, Philippe, Ritieni, Alberto, Di Minno, Giovanni, Mälarstig, Anders, Gigante, Bruna, 'Federico II' University of Naples Medical School, Karolinska Institutet [Stockholm], University of Glasgow, Centro Cardiologico Monzino [Milano], Dpt di Scienze Cliniche e di Comunità [Milano] (DISCCO), Università degli Studi di Milano [Milano] (UNIMI)-Università degli Studi di Milano [Milano] (UNIMI)-Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), University of Milan, University Medical Center Groningen [Groningen] (UMCG), Takeda Pharmaceuticals International GmbH, Perugia General Hospital, Service d’Endocrinologie, Métabolisme et Prévention des Risques Cardio-Vasculaires [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Groningen Kidney Center (GKC), Castaldo, L., Laguzzi, F., Strawbridge, R. J., Baldassarre, D., Veglia, F., Vigo, L., Tremoli, E., de Faire, U., Eriksson, P., Smit, A. J., Aubrecht, J., Leander, K., Pirro, M., Giral, P., Ritieni, A., Di Minno, G., Malarstig, A., and Gigante, B.

Subjects
Male, lcsh:QH426-470, carotid intima-media thickness, Polymorphism, Single Nucleotide, INTIMA-MEDIA THICKNESS, Article, TM6SF2, Carotid intima-media thickne, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Humans, cardiovascular diseases, CONFERS SUSCEPTIBILITY, Genetic Association Studies, POPULATION, Aged, RISK, CHOLESTEROL, non-alcoholic fatty liver disease, Alanine Transaminase, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Atherosclerosis, lcsh:Genetics, Carotid Arteries, Amino Acid Substitution, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, CARDIOVASCULAR-DISEASE, cardiovascular system, CORONARY-ARTERY-DISEASE, HEART, Female, alanine aminotransferase and genetic association study, GCKR
Abstract

Non-alcoholic fatty liver disease (NAFLD) and atherosclerosis-related cardiovascular diseases (CVD) share common metabolic pathways. We explored the association between three NAFLD-associated single nucleotide polymorphisms (SNPs) rs738409, rs10401969, and rs1260326 with sub-clinical atherosclerosis estimated by the carotid intima-media thickness (c-IMT) and the inter-adventitia common carotid artery diameter (ICCAD) in patients free from clinically overt NAFLD and CVD. The study population is the IMPROVE, a multicenter European study (n = 3711). C-IMT measures and ICCAD were recorded using a standardized protocol. Linear regression with an additive genetic model was used to test for association of the three SNPs with c-IMT and ICCAD. In secondary analyses, the association of the three SNPs with c-IMT and ICCAD was tested after stratification by alanine aminotransferase levels (ALT). No associations were found between rs738409, rs1260326, rs10401969, and c-IMT or ICCAD. Rs738409-G and rs10401969-C were associated with ALT levels (p &lt, 0.001). In patients with ALT levels above 28 U/L (highest quartile), we observed an association between rs10401969-C and c-IMT measures of c-IMTmax and c-IMTmean-max (p = 0.018 and 0.021, respectively). In conclusion, NAFLD-associated SNPs do not associate with sub-clinical atherosclerosis measures. However, our results suggest a possible mediating function of impaired liver function on atherosclerosis development.

Published
2020

110. Biological effects of Trichoderma harzianum peptaibols on mammalian cells

Author

Peltola, Joanna, Ritieni, Alberto, Grigoriev, Pavel A., Mikkola, Raimo, Pocsfalvi, Gabriella, Salkinoja-Salonen, Mirja S., and Andersson, Maria A.

Subjects
Epithelial tumors -- Causes of, Methanol -- Research, Spermatozoa -- Research, Biological sciences
Abstract

The substances responsible for the inhibition boar spermatozoa motility in the extract of Trichoderma harzianum strain ES39 were identified as a peptaibol group of peptides, and the peptaibols produced by T. harzianum strain ES39 that were dissolved in methanol was examined. The peptaibols were found to damage the cell membrane barrier function of boar spermatozoa and dissipate the human lung epithelial carcinoma cell line.

Published
2004

111. Species diversity of and toxin production by Gibberella fujikuroi species complex strains isolated from native prairie grasses in Kansas

Author

Leslie, John F., Zeller, Kurt A., Logrieco, Antonio, Mule, Giuseppina, Moretti, Antonio, and Ritieni, Alberto

Subjects
Bacterial toxins -- Research, Gibberellins -- Research, Biological sciences
Abstract

Species diversity and toxin production displayed by Gibberella fujikurou species complex strains that were isolated from native prairie grasses in Kansas were studied. The Fusarium community contains some species that are probably undescribed and could probably be important and useful in the field of agricultural research.

Published
2004

113. Chemical Composition of Green Pea (Pisum sativum L.) Pods Extracts and Their Potential Exploitation as Ingredients in Nutraceutical Formulations.

Author

Castaldo, Luigi, Izzo, Luana, Gaspari, Anna, Lombardi, Sonia, Rodríguez-Carrasco, Yelko, Narváez, Alfonso, Grosso, Michela, and Ritieni, Alberto

Abstract

Agro-industrial wastes contain a large number of important active compounds which can justify their use as innovative ingredients in nutraceutical products. This study aimed to provide a complete analysis of active molecules, namely (poly)phenols in pea pods water-based extracts, through a UHPLC-Q-Orbitrap HRMS methodology. Data showed that 5-caffeoylquinic acid, epicatechin, and hesperidin were the most relevant (poly)phenols found in the assayed extracts, with a mean value of 59.87, 29.46, and 19.94 mg/100 g, respectively. Furthermore, changes in antioxidant capacity and bioaccessibility of total phenolic compounds (TPC) after the simulated gastrointestinal (GI) process were performed using spectrophotometric assays (FRAP, DPPH, ABTS, and TPC by Folin-Ciocalteu). The acid-resistant capsules (ARC) and the non-acid resistant capsules (NARC) containing the pea pod extract underwent simulated GI digestion. The results suggested that the ARC formulations were able to preserve the active compounds along the simulated GI process, highlighting a higher TPC value and antioxidant capacity than the NARC formulations and the not-encapsulated extracts. Hence, the pea pods water-based extracts could be utilized as a potential alternative source of active compounds, and the use of ARC could represent a suitable nutraceutical formulation to vehiculate the active compounds, protecting the chemical and bioactive properties of (poly)phenols. [ABSTRACT FROM AUTHOR]

Published
2022
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123. An Innovative Olive Pâté with Nutraceutical Properties

Author

Cavallo, Pierpaolo, primary, Dini, Irene, additional, Sepe, Immacolata, additional, Galasso, Gennaro, additional, Fedele, Francesca Luisa, additional, Sicari, Andrea, additional, Bolletti Censi, Sergio, additional, Gaspari, Anna, additional, Ritieni, Alberto, additional, Lorito, Matteo, additional, and Vinale, Francesco, additional

Published
2020
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124. Nationwide survey reveals high diversity of Fusarium species and related mycotoxins in Brazilian rice: 2014 and 2015 harvests

Author

Moreira, Gláucia M., primary, Nicolli, Camila P., additional, Gomes, Larissa B., additional, Ogoshi, Cláudio, additional, Scheuermann, Klaus K., additional, Silva-Lobo, Valácia L., additional, Schurt, Daniel A., additional, Ritieni, Alberto, additional, Moretti, Antonio, additional, Pfenning, Ludwig H., additional, and Del Ponte, Emerson M., additional

Published
2020
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130. Mars Regolith Simulant Ameliorated by Compost as in situ Cultivation Substrate Improves Lettuce Growth and Nutritional Aspects

Author

Duri, Luigi G., primary, El-Nakhel, Christophe, additional, Caporale, Antonio G., additional, Ciriello, Michele, additional, Graziani, Giulia, additional, Pannico, Antonio, additional, Palladino, Mario, additional, Ritieni, Alberto, additional, De Pascale, Stefania, additional, Vingiani, Simona, additional, Adamo, Paola, additional, and Rouphael, Youssef, additional

Published
2020
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132. Variation in Macronutrient Content, Phytochemical Constitution and In Vitro Antioxidant Capacity of Green and Red Butterhead Lettuce Dictated by Different Developmental Stages of Harvest Maturity

Author

El-Nakhel, Christophe, primary, Pannico, Antonio, additional, Graziani, Giulia, additional, Kyriacou, Marios C., additional, Giordano, Maria, additional, Ritieni, Alberto, additional, De Pascale, Stefania, additional, and Rouphael, Youssef, additional

Published
2020
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134. Selenium Biofortification Impacts the Nutritive Value, Polyphenolic Content, and Bioactive Constitution of Variable Microgreens Genotypes

Author

Pannico, Antonio, primary, El-Nakhel, Christophe, additional, Graziani, Giulia, additional, Kyriacou, Marios C., additional, Giordano, Maria, additional, Soteriou, Georgios A., additional, Zarrelli, Armando, additional, Ritieni, Alberto, additional, De Pascale, Stefania, additional, and Rouphael, Youssef, additional

Published
2020
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135. Phenolic Constitution, Phytochemical and Macronutrient Content in Three Species of Microgreens as Modulated by Natural Fiber and Synthetic Substrates

Author

Kyriacou, Marios C., primary, El-Nakhel, Christophe, additional, Pannico, Antonio, additional, Graziani, Giulia, additional, Soteriou, Georgios A., additional, Giordano, Maria, additional, Palladino, Mario, additional, Ritieni, Alberto, additional, De Pascale, Stefania, additional, and Rouphael, Youssef, additional

Published
2020
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143. Nationwide survey reveals high diversity of Fusarium species and related mycotoxins in Brazilian rice: 2014 and 2015 harvests

Author

Moreira, Gláucia Mara, primary, Nicolli, Camila Primieri, additional, Gomes, Larissa Bitencourt, additional, Ogoshi, Claudigo, additional, Scheuermann, Klaus K., additional, da Silva Lobo, Valácia L., additional, Schurt, Daniel A., additional, Ritieni, Alberto, additional, Moretti, Antonio, additional, Pfenning, Ludwig H., additional, and Del Ponte, Emerson Medeiros, additional

Published
2019
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144. Genotype-Specific Modulatory Effects of Select Spectral Bandwidths on the Nutritive and Phytochemical Composition of Microgreens

Author

Kyriacou, Marios C., primary, El-Nakhel, Christophe, additional, Pannico, Antonio, additional, Graziani, Giulia, additional, Soteriou, Georgios A., additional, Giordano, Maria, additional, Zarrelli, Armando, additional, Ritieni, Alberto, additional, De Pascale, Stefania, additional, and Rouphael, Youssef, additional

Published
2019
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148. Metabolites of a Drechslera sp. endophyte with potential as biocontrol and bioremediation agent.

Author

d'Errico, Giada, Aloj, Veronica, Flematti, Gavin R., Sivasithamparam, Krishnapillai, Worth, Carol M., Lombardi, Nadia, Ritieni, Alberto, Marra, Roberta, Lorito, Matteo, and Vinale, Francesco

Subjects
ENDOPHYTIC fungi, BIOLOGICAL pest control agents, METABOLITES, ALTERNARIA alternata, BOTRYTIS cinerea, RHIZOCTONIA solani
Abstract

Endophytic fungi have several well-established beneficial effects on plant health and growth, and are a huge source of bioactive compounds. The endophyte Drechslera sp. strain 678, isolated from the roots of an Australian native grass Neurachne alopecuroidea, demonstrated efficacy against four plant pathogens (Pythium ultimum, Rhizoctonia solani, Botrytis cinerea, Alternaria alternata). In addition, strain 678 was capable of degrading a common additive used in gasoline, known as methyl tertiary-butyl ether (MtBE). Thus, the organic extracts obtained from the culture filtrate of strain 678 were studied. Metabolomic analysis revealed the presence of two major bioactive metabolites, monocerin and an alkynyl substituted epoxycyclohexenone derivative, which showed good antifungal activity. The Drechslera sp. strain 678 and its compounds show promise for applications in biocontrol and bioremediation activities in agriculture or as a remediation option for MtBE contamination in soil. [ABSTRACT FROM AUTHOR]

Published
2021
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149. Occurrence of fusaproliferin and beauvericin in Fusarium-contaminated livestock feed in Iowa

Author

Munkvold, Gary, Stahr, H.M., Logrieco, Antonio, Moretti, Antonio, and Ritieni, Alberto

Subjects
Fusarium -- Research, Livestock -- Research, Feed research -- Analysis, Biological sciences
Abstract

A study was conducted to analyze Fusarium fungal contaminants and related mycotoxins in maize feed livestock samples. Single-conidium isolates were cultured in autoclaved yellow maize kernels adjusted to about 45% moisture in Erlenmeyer flasks. High performance liquid chromatography was then carried out to dt amounts of beauvericin and fusaproliferin in the feed samples. Results indicated the natural occurrence of fusaproliferin outside Italy and of the natural occurrence of beauvericin in North America.

Published
1998

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