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583 results on '"Ruocco, Vincenzo"'

103. Drug-triggered pemphigus in a predisposed woman

Author

RUOCCO, Vincenzo, GOMBOS F, LOMBARDI ML, Ruocco, Vincenzo, Gombos, F, and Lombardi, Ml

Subjects
Adult, Feprazone, Ceftriaxone, Humans, Female, Pemphigus
Abstract

A 31-year-old woman with three pemphigus-prone antigens in her HLA haplotype (B7, DR4, DQw7) developed the disease soon after taking a pyrazolone derivative, viz. feprazone. The pemphigus lesions persisted despite withdrawal of the drug and worsened appreciably when she used ceftriaxone (a new cephalosporin with three sulphur atoms) for a bout of acute pharyngitis. Thiol groups formed from the metabolic breakdown of ceftriaxone are thought to have promoted acantholysis via a biochemical route. Genetic predisposition alone ('the soil') may be essential, though not per se sufficient for outbreak of pemphigus; the intervention of exogenous, heterogeneous factors ('the seed') often seems decisive in triggering full-blown disease.

Published
1992

104. Isotopic response

Author

WOLF R, FILIOLI FG, RUOCCO, Vincenzo, Wolf, R, Ruocco, Vincenzo, and Filioli, Fg

Subjects
Dermatology
Published
1997
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106. A Possible Mechanism for Phenol‐Induced Pemphigus

Author

Goldberg Ilan, Srebrnik Avigdor, Ruocco Eleonora, Brenner Sarah, and Ruocco Vincenzo

Subjects
Proteases, integumentary system, Acantholysis, Pemphigus vulgaris, General Medicine, Biology, medicine.disease, Pathogenesis, Pemphigus, Phenols, immune system diseases, In vivo, Immunology, medicine, Humans, Genetic Predisposition to Disease, Tumor necrosis factor alpha, skin and connective tissue diseases, Plasminogen activator
Abstract

A possible mechanism for phenol-induced pemphigus lesions in genetically predisposed individuals is proposed that accounts for in vitro observations and cases of biochemical acantholysis, as well as the in vivo acantholysis in pemphigus induced by phenols. The mechanism involves the induction of interleukin-1a and tumor necrosis factor-a release by keratinocytes. These cytokines in turn have been shown to be involved in the regulation and synthesis of complement and proteases like plasminogen activator, which have been implicated in the pathogenesis of acantholysis in pemphigus vulgaris.

Published
2006
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123. Wolf's isotopic response

Author

Wolf, Ronni, primary, Wolf, Danny, additional, Ruocco, Eleonora, additional, Brunetti, Giampiero, additional, and Ruocco, Vincenzo, additional

Published
2011
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125. MDM2 and CDKN1A gene polymorphisms and risk of Kaposi’s sarcoma in African and Caucasian patients

Author

Tornesello, Maria Lina, primary, Buonaguro, Luigi, additional, Cristillo, Medea, additional, Biryahwaho, Bennon, additional, Downing, Robert, additional, Hatzakis, Angelo, additional, Alessi, Elvio, additional, Cusini, Marco, additional, Ruocco, Vincenzo, additional, Viviano, Enza, additional, Romano, Nino, additional, Katongole-Mbidde, Edward, additional, and Buonaguro, Franco M., additional

Published
2010
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126. Human herpesvirus type 8 variants in Kaposi's sarcoma before and after AIDS era

Author

Tornesello, Maria Lina, primary, Biryahwaho, Benon, additional, Downing, Robert, additional, Hatzakis, Angelo, additional, Alessi, Elvio, additional, Cusini, Marco, additional, Ruocco, Vincenzo, additional, Loquercio, Giovanna, additional, Katongole-Mbidde, Edward, additional, Buonaguro, Luigi, additional, and Buonaguro, Franco M, additional

Published
2010
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142. Sunscreens

Author

Wolf, Ronni, primary, Wolf, Danny, additional, Morganti, Pierfrancesco, additional, and Ruocco, Vincenzo, additional

Published
2001
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