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1,124 results on '"Strupp M"'

124. Acute vestibulopathy

Author

Bronstein, A M, Brandt, T, Strupp, M, and Benson, J

Subjects
Vestibular apparatus, Labyrinth (Ear) -- Inflammation
Published
2000

126. Dosisabhängige Erhöhung des cochleären Blutflusses durch Betahistin-Hydrochlorid

Author

Canis, M, Bertlich, M, Strieth, S, Strupp, M, and Ihler, F

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Betahistin-Hydrochlorid ist strukturell mit Histamin verwand und wirkt als H1-Agonist und H3-Antagonist. Über die Wirkungsweise von Betahistin ist bisher wenig bekannt. Als vasoaktives Medikament könnte es jedoch die cochleäre Mikrozirkulation beeinflussen und somit klinisch[for full text, please go to the a.m. URL], 83. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie

Published
2012
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133. Der Einfluss von Cholesterin auf die Motilität äußerer cochleärer Haarzellen und das Motorprotein Prestin

Author

Canis, M, Schmidt, J, Strupp, M, Jahn, K, and Suckfüll, M

Subjects
ddc: 610, otorhinolaryngologic diseases, sense organs, 610 Medical sciences, Medicine
Abstract

Objectives: Elevated serum cholesterol is linked to inner ear disorders and may influence hearing by altering membrane properties of outer hair cells (OHC) and by affecting the motor protein prestin. In this study we wanted to answer the question, if cholesterol modulates electromotility of OHCs and[for full text, please go to the a.m. URL], 93. Jahrestagung der Vereinigung Südwestdeutscher Hals-Nasen-Ohrenärzte

Published
2009
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143. Effects of acetyl-DL-leucine in patients with cerebellar ataxia: a case series

Author

Strupp, M., Teufel, J., Habs, M., Feuerecker, R., Muth, C., Warrenburg, B.P.C. van de, Klopstock, T., Feil, K., Strupp, M., Teufel, J., Habs, M., Feuerecker, R., Muth, C., Warrenburg, B.P.C. van de, Klopstock, T., and Feil, K.

Abstract

Item does not contain fulltext, No existing medication has yet been shown to convincingly improve cerebellar ataxia. Therefore, the identification of new drugs for its symptomatic treatment is desirable. The objective of this case series was to evaluate the efficacy of treatment of cerebellar ataxia with the amino acid acetyl-DL-leucine (Tanganil). Thirteen patients (eight males, median age 51 years) with degenerative cerebellar ataxia of different etiologies (SCA1/2, ADCA, AOA, SAOA) were treated with acetyl-DL-leucine (5 g/day) without titration for 1 week. Motor function was evaluated by changes in the Scale for the Rating and Assessment of Ataxia (SARA) and in the Spinocerebellar Ataxia Functional Index (SCAFI) during treatment compared to a baseline examination. Quality of life (EuroQol-5D-3L) and side effects were also assessed. Mean total SARA decreased remarkably (p = 0.002) from a baseline of 16.1 +/- 7.1 to 12.8 +/- 6.8 (mean +/- SD) on medication. There were also significant improvements in sub-scores for gait (p = 0.022), speech (p = 0.007), finger-chase (p = 0.042), nose-finger-test (p = 0.035), rapid-alternating-movements (p = 0.002) and heel-to-shin (p = 0.018). Furthermore, patients showed better performance in the SCAFI consisting of the 8-m-walking-time (8 MW, p = 0.003), 9-Hole-Peg-Test of the dominant hand (9HPTD, p = 0.011) and the PATA rate (p = 0.005). Quality of life increased during treatment (p = 0.003). No side effects were reported. In conclusion, acetyl-DL-leucine significantly improved ataxic symptoms without side effects and therefore showed a good risk-benefit profile. These findings need to be confirmed in placebo-controlled trials.

Published
2013

145. Consensus Paper: Management of Degenerative Cerebellar Disorders

Author

Ilg, W., primary, Bastian, A. J., additional, Boesch, S., additional, Burciu, R. G., additional, Celnik, P., additional, Claaßen, J., additional, Feil, K., additional, Kalla, R., additional, Miyai, I., additional, Nachbauer, W., additional, Schöls, L., additional, Strupp, M., additional, Synofzik, M., additional, Teufel, J., additional, and Timmann, D., additional

Published
2013
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148. Vestibuläre Migräne

Author

Obermann, M., additional, Strupp, M., additional, Holle, D., additional, Straube, A., additional, Förderreuther, S., additional, Katsarava, Z., additional, and Diener, H., additional

Published
2013
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