101. Functioning in bipolar disorder with substance abuse/dependence in a community sample of young adults
- Author
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Flávio Kapczinski, Luciano Dias de Mattos Souza, Taiane de Azevedo Cardoso, Karen Jansen, Thaíse Campos Mondin, Ricardo Azevedo da Silva, and Pedro Vieira da Silva Magalhães
- Subjects
Adult ,Male ,medicine.medical_specialty ,Bipolar Disorder ,Substance-Related Disorders ,Cross-sectional study ,Health Status ,Comorbidity ,Young Adult ,mental disorders ,Prevalence ,medicine ,Humans ,Bipolar disorder ,Cognitive skill ,Young adult ,Social Behavior ,Psychiatry ,Mini-international neuropsychiatric interview ,Neuropsychology ,medicine.disease ,Substance abuse ,Psychiatry and Mental health ,Clinical Psychology ,Cross-Sectional Studies ,Female ,Psychology ,Brazil ,Clinical psychology - Abstract
Aim: To assess the functional impairment of young adults with bipolar disorder with substance abuse/ dependence comorbidity. Method: Cross-sectional study within a community sample. Bipolar Disorder was assessed by qualified psychologists using The Mini International Neuropsychiatric Interview – PLUS (MINI-PLUS). Substance abuse and dependence was assessed using the “Alcohol, Smoking and Substance Involvement Screening Test” (ASSIST). Functional impairment was assessed using the Functional Assessment Short Test (FAST). Results: The sample included 1259 young adults. The prevalence of Bipolar Disorder (BD) without Substance Abuse/Dependence (SAD) comorbidity was 5.9% (n ¼74), and the prevalence of bipolar disorder with substance abuse/dependence comorbidity was 1.4% (n¼17). Both groups showed higher impairment in overall functioning, interpersonal relationship, and leisure time as compared to controls. In addition, BDþSAD showed higher impairment in the cognitive functioning domain of FAST. Limitation: A battery of neuropsychological tests was not performed. Conclusion: Functional impairment is associated with BD, independently of substance abuse or dependence. In addition, BDþSAD present a more severe impairment in the cognitive domain of FAST as compared to controls. & 2015 Published by Elsevier B.V.
- Published
- 2015
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