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• Tetrahedral DNA nanostructure provides an effective drug delivery vehicle. • We constructed a 3D-bioprinted scaffold loaded with TDN-clindamycin complex. • The novel scaffold was biocompatible, with osteogenic and antimicrobial properties. • The scaffold significantly improved repair in rat model of infected bone defect. Infection of bone defects is a common clinical problem that negatively impacts bone repair and may result in the development of antibiotic resistance due to the long-term use of antibiotics. To the best of our knowledge, integrating tetrahedral DNA nanostructure (TDN) drug delivery with 3D bioprinting has not been reported to treat infected bone defects. However, numerous studies have focused on effectively controlling infected bone defects and achieving functional reconstruction. In this study, TDN was proposed as a drug delivery vehicle to enhance cell penetration and the antibacterial properties of clindamycin (CLI), a common antibiotic used to treat osteomyelitis. A 3D hybrid scaffold loaded with TDN-CLI complexes was constructed using bioprinting technology. Its structure and biological properties were characterized, and the scaffold was further applied to treat methicillin-resistant Staphylococcus aureus (MRSA) infection in a rat model of bone defect. The results demonstrated that the TDN-CLI-loaded 3D bioprinted hybrid scaffold possessed excellent biocompatibility, outstanding osteogenic and antimicrobial activity, and significantly improved the repair of infected bone defects in the rat model. The TDN-CLI-loaded hybrid scaffold developed in the current study has broad application prospects for treating infected bone defects. [ABSTRACT FROM AUTHOR]

On page 2091 conductive polypyrrole is integrated by Z. Liu, J. Zhai, and co‐workers into alumina nanopore arrays to construct organic/inorganic hybrid nanochannels. The protonation and deprotonation of surface groups upon pH variation contributes to the pH‐tunable ion rectification. Positive charges in polypyrrole layer induced by the cooperative effect of light and protons are used to regulate the channel flux, which results in a light‐responsive ion current. [ABSTRACT FROM AUTHOR]

Bioadhesive microporous architecturesthat mimic the functionsof a natural extracellular matrix (ECM) were prepared by self-assemblingpolydopamine (PDA) microcapsules, which not only favor cell adhesionand growth, but also facilitate growth factor immobilization and release.PDA-coated polystyrene (PS) microspheres are synthesized by polymerizationof dopamine on sulfonated PS microspheres and then assembled usingpositively charged chitosan (CHI) layers as link agents. After thePS core templates were removed, microporous architectures composedof PDA microcapsules were obtained. The produced microporous PDA architectureshave a high capability of adsorbing BMP-2 and realize the sustainedrelease of BMP-2. More importantly, the bioadhesive micro architectureand its immobilized BMP-2 synergistically enhance the activity andosteogenetic differentiation of bone marrow mesenchymal stem cells(BMSCs). Both supercell adhesion and BMP-2 immobilization abilityof these architectures are attributed to the intrinsic adhesive natureof PDA and the porous architectures via the assembly of PDA microcapsules.The bioadhesive microporous PDA architectures with both cell affinitiveand GF release features have a great potential to mimic natural ECMfor modifying various medical devices in the fields of tissue engineeringand regenerative medicine. [ABSTRACT FROM AUTHOR]

Background Planners have relied on the urban development boundary (UDB)/urban growth boundary (UGB) and central business district (CBD) to encourage contiguous urban development and conserve infrastructure. However, no studies have specifically examined the relationship between proximity to the UDB/UGB and CBD and walking behavior. Purpose To examine the relationship between UDB and CBD distance and walking in a sample of recent Cuban immigrants, who report little choice in where they live after arrival to the U.S. Methods Data were collected in 2008–2010 from 391 healthy, recent Cuban immigrants recruited and assessed within 90 days of arrival to the U.S. who resided throughout Miami–Dade County FL. Analyses in 2012–2013 examined the relationship between UDB and CBD distances for each participant’s residential address and purposive walking, controlling for key sociodemographics. Follow-up analyses examined whether Walk Score ® , a built-environment walkability metric based on distance to amenities such as stores and parks, mediated the relationship between purposive walking and each of UDB and CBD distance. Results Each one-mile increase in distance from the UDB corresponded to an 11% increase in the number of minutes of purposive walking, whereas each one-mile increase from the CBD corresponded to a 5% decrease in the amount of purposive walking. Moreover, Walk Score mediated the relationship between walking and each of UDB and CBD distance. Conclusions Given the lack of walking and walkable destinations observed in proximity to the UDB/UGB boundary, a sprawl repair approach could be implemented, which strategically introduces mixed-use zoning to encourage walking throughout the boundary’s zone. [ABSTRACT FROM AUTHOR]

Soil respiration is an important component of the carbon cycle and is also recognized as one of the primary pathways that release CO2from the soil into the atmosphere in terrestrial ecosystems. Soil CO2flux resulting from soil microbial activity and root respiration is one of the major components of the total carbon flux in agro-ecosystems. However, the impact of agronomic practices such as mulching on soil respiration in greenhouses has been less thoroughly studied. Consequently, field experiments were conducted during the growing seasons of 2011 and 2012 in greenhouse to evaluate soil respiration and the biotic and abiotic factors that influence it in hot pepper cultivation under four types of mulch practices (without mulch, wheat straw mulch, plastic film mulch, and combined mulch with plastic film and wheat straw). Soil water content had an overriding influence on soil respiration in hot pepper culture during the growing season under mulching treatments in a greenhouse, whereas the influence of soil temperature was relatively less. Additionally, the study showed that root biomass and root vigor should also be incorporated as predictor variables for soil respiration under mulching in greenhouses. [ABSTRACT FROM AUTHOR]

Immunotherapy is a powerful way to treat cancer, however, systemic treatment-associated adverse effects remain a major concern. In this study, a bioadhesive injectable hydrogel is developed to provide localized immune niches for tumor microenvironment immunomodulation and cancer catalytic immunotherapy. First, a phenolic single atom nanozyme (SAN) was developed by in situ synthesis of Pd single atom on catechol-grafted carbon-quantum-dot (DA-CQD@Pd) templates. Then, the bioadhesive injectable hydrogel consisting of DA-CQD@Pd SAN and immune adjuvant CpGODN was formed through SAN-catalyzed free-radical polymerization. The SAN exhibited peroxidase-like activity to generate ROS and kill tumor cells through catalytic therapy. The hydrogel locally released CpGODN in a sustained manner, which limited the risk of systemic exposure, reducing the impact of CpGODN toxicity, and protecting CpGODN from degradation. The bioadhesive hydrogel immobilized around solid tumor to provide an immune response site after injection. When combined it with the administration of immune checkpoint inhibitor anti-PD-L1, the hydrogel realized localized immunomodulation, maximized therapeutic efficacy and prevents tumor metastasis via a catalytic immunotherapy. [ABSTRACT FROM AUTHOR]

[Display omitted] • CsPbBr 3 nanocubes, nanorods and nanowires are deposited on 2D NMF, respectively. • The 2D NMF as cocatalyst improves the photocatalytic activity in CO 2 -to-CO conversion. • The photocatalytic enhancement is greatly dependent on the aspect ratio of CsPbBr 3. • The elongation of CsPbBr 3 enlarges the ΔE of CB and improves the charge separation. All-inorganic CsPbBr 3 perovskites have been regarded as promising candidates for photocatalytic CO 2 reduction, but the conversion efficiency is limited by serious charge recombination and poor surface reactivity. Herein, a two-dimensional Ni based metal-organic framework (NMF) has been employed as a cocatalyst, which not only acts as an electron extractor in enhancing the electron-hole separation, but also serves as a CO 2 capturing agent in facilitating the adsorption and activation of CO 2 molecules. As a result, 1.8, 2.5 and 4.1-fold enhancement in CO production has been realized for CsPbBr 3 nanocubes, nanorods and nanowires, respectively, which is proved to be positively correlated with the aspect ratio of CsPbBr 3. The aspect ratio dependent photocatalytic enhancement is attributed to the increased energy difference at the interface between the conduction band of CsPbBr 3 and NMF with the elongation of CsPbBr 3 , which produces an enlarged driving force for promoted interfacial electron transfer and superior charge separation properties. [ABSTRACT FROM AUTHOR]

Bone defect caused by trauma, tumor, infection, and other reasons is a thorny problem that needs to be solved in orthopedic clinic. Customized bone repair biomaterials and their fabrication still need to be explored. Three-dimensional (3D) printing is a high-speed fabrication process for bone tissue biomaterials, which paves the way of solving clinical bone defect problems in a new way. In this study, the fused deposition modeling (FDM) technology was used to prepare the composite scaffolds of polylactic acid (PLA) and nano-hydroxyapatite (n-HA). The composite scaffold was optimized by material characterization, mechanical property test, and in vitro bone marrow mesenchymal stem cells biocompatibility test. Finally, a rabbit model was established to evaluate the osteogenic ability of PLA/n-HA scaffolds in vivo. The results showed that the PLA/n-HA composites proposed in this study were highly printable, and the printed scaffold showed tunable mechanical strength accompanied by the proportion of n-HA components. The biocompatibility and osteogenic induction properties were proved better than that of the pure PLA scaffold. This composite scaffold of PLA and n-HA provides a promising strategy for the repair of large bone defects. [ABSTRACT FROM AUTHOR]

Abstract: A facile, effective and template/surfactant-free hydrothermal route in the presence of sodium bicarbonate was developed to synthesize highly uniform single-crystalline hydroxyapatite (HA) nanorods with the lengths of several hundred nanometers and aspect ratio up to ∼20. One dimensional (1-D) growth and aspect ratio could be controlled by hydrothermal reaction time and temperature. The longitudinal axis, also the growth direction of the nanorods, is parallel to the [001] direction of HA hexagonal crystal structure. [Copyright &y& Elsevier]

We report bulk superconductivity (SC) in Ca 3 Ir 4 Sn 13 by means of 119 Sn nuclear magnetic resonance (NMR) experiments. Two classical signatures of BCS superconductivity in spin-lattice relaxation rate (1/ T 1 ), namely the Hebel–Slichter coherence peak just below the T c , and the exponential decay in the superconducting phase, are evident. The noticeable decrease of 119 Sn Knight shift below T c indicates spin-singlet superconductivity. The temperature dependence of the spin-lattice relaxation rate 119 (1/ T 1 ) is convincingly described by the multigap isotropic superconducting gap. NMR experiments do not witness any sign of enhanced spin fluctuations. [ABSTRACT FROM AUTHOR]

Polylactic acid/Hydroxyapatite (PLA/HA) composite was widely studied and applied in the field of biomaterials for its good processability, bioactivity, and mechanical properties. In addition to traditional preparation methods, additive manufacturing has also been adopted to prepare PLA/HA composites with customized geometries. This work combined the comprehensive optimized PLLA (L-polylactic acid)/nano-HA (nHA) composite with the low-cost and stable Fused deposition modeling (FDM) technology to successfully prepare PLLA/nHA porous bone repair scaffolds. The results showed that PLLA/nHA composite ink satisfied the smoothness of printing, and the accuracy also met the requirements of personalized bone repair application. The high loaded nHA scaffold had suitable compressive strength was significantly higher than those of pure HA ceramic scaffold and cancellous bone. Besides, in vitro bone-like apatite formation on the surface in the degradation process and in vivo evaluations further verified its good osteogenic property. Compared with other complex and cutting-edge 3D printing technologies, this study provides a low-cost, stable, simple and fast way to realize personalized printing of bone repair scaffolds, which is undoubtedly conductive to the improvement and rapid deployment of personalized biomaterials in clinical applications. Unlabelled Image • Comprehensive optimized PLLA/nano-hydroxyapatite composite was made successfully for bone repair scaffold printing. • Bone-like apatite can form on the scaffold surface in vitro degradation experiments just in PBS, indicating the high bioactivity of scaffold. • The high loaded nano- hydroxyapatite scaffold has suitable compressive strength and good osteogenic property. • This study provides a low-cost, stable, simple and fast way to realize personalized printing of bone repair scaffolds. [ABSTRACT FROM AUTHOR]

Titanium has been widely used in medical implants for hard tissue replacements. Nevertheless, the bioinert innate oxide layer on the titanium implant surface usually makes the implant fail to osseointegrate with the surrounding tissue after surgery. To improve the bioactivity of titanium implants, the deposition of calcium phosphate (CaP) coatings attracts much research interest owing to the excellent bioactivity and biocompatibility of CaP. This work successfully developed a promising synthetic method to prepare uniform fluoridated CaP coatings with ultrathin thicknesses (∼170 nm) and desired phases on acid etched pure titanium (AETi) substrates. A dense ultrathin coating with a dominant phase of fluoridated amorphous CaP (FACP) was obtained by an electrochemical deposition method in galvanostatic mode. After a heat treatment at 600 °C for 3 h in a humid atmosphere, the as-prepared coating was transformed to a coating with a dominant phase of fluoridated hydroxyapatite (FHA). Additionally, the dominant phase of the coating could be transformed from FACP to α-tricalcium phosphate (α-TCP) by a heat treatment at 800 °C for 3 h. Unlike previously reported fluoridated CaP coatings with thicknesses of around several micrometers, the ultrathin thickness could potentially enhance the adhesive strength and ductility of coating. Notably, the fluorine incorporation in the coating could bring in additional benefits such as lower solubility, higher antibacterial activity, and higher adhesive strength. Electrochemical deposition associated with post heat treatment could obtain fluoridated CaP coatings with different desired phases in a controllable manner, which is very important since CaPs with different phases possess different properties and may be suitable for different biomedical applications. This study proposed a promising, simple, and low-cost method which can endow complex-shaped titanium implants with better bioactivity for dental and orthopedic applications. • Unlike previously reported fluoridated CaP coatings with thicknesses of around several micrometers, the ultrathin thickness (∼170 nm) could potentially enhance the adhesive strength and ductility of coating. • The fluorine incorporation in the coating could bring additional benefits such as lower solubility, higher antibacterial activity, and higher adhesive strength. • Electrochemical deposition associated with post heat treatment could obtain fluoridated CaP coatings with different desired phases in a controllable manner, which is very important since CaPs with different phases possess different properties and may be suitable for different biomedical applications. • Proposed a promising, simple, and lower-cost route to endow complex-shaped titanium implants with better bioactivity, which could be widely applied in dental and orthopedic applications. [ABSTRACT FROM AUTHOR]

Recently, the cicada-inspired nanostructured surfaces have attracted much interest because they possess remarkable bactericidal ability. However, Gram-positive bacteria are less damageable by the nanopillar structure of a cicada wing surface compared to Gram-negative species. To overcome this shortcoming, fluoridated hydroxyapatite (FHA) is employed owing to its effective antibacterial ability against both Gram-negative and Gram-positive bacteria. Here, we design a novel potential antibacterial surface by combining the cicada wing-like nanopillar structure and the FHA together to potentially exert the advantages of physical and chemical antibacterial strategies simultaneously for battling the antibiotic-resistant pathogenic bacteria more effectively. Cicada-inspired FHA nanostructured surfaces have been successfully fabricated on acid-etched titanium (AETi) plates using an electrochemical additive manufacturing (ECAM) method for the first time. The as-prepared FHA nanopillar array consists of close-packed individual nanopillars with diameters, heights, and aspect ratios of ~65–95 nm, ~380–510 nm, and ~4.5–7.5, respectively. The chemical composition of the FHA nanopillar array is similar to that of the Ca 10 (PO 4) 6 (OH)F. Individual FHA nanopillars possess high crystallinity, long-range regularity, and flaw-free lattices with the [0001] orientation. Our new, cost-effective, and time-saving method for fabricating cicada-inspired FHA nanostructured surfaces could potentially endow orthopedic and dental implants with enhanced antibacterial performance for biomedical applications. Unlabelled Image • We firstly proposed an electrochemical additive manufacturing method for preparing cicada-inspired nanostructured surfaces. • This promising synthesis method is novel, cost-effective, and time-saving. • This study focused on fabricating nanostructures with bioactive and biocompatible fluoridated hydroxyapatite pioneeringly. • We designed the biomimetic nanostructures by combining the advantages of physical and chemical antibacterial strategies. • The nanostructures could potentially endow medical implants with more effective non-antibiotic antibacterial activity. [ABSTRACT FROM AUTHOR]

Highlights: A universal strategy was proposed to producing conductive, redox-active, and hydrophilic sulfonated lignin-conductive polymer nanoparticles (CP/LS NPs). By incorporating the CP/LS NPs into hydrogel network, a good conductive, adhesive, and tough hydrogel was obtained. The redox-active NPs maintained enough catechol groups inner the hydrogel for adhesiveness. Conductive polymers (CPs) are generally insoluble, and developing hydrophilic CPs is significant to broaden the applications of CPs. In this work, a mussel-inspired strategy was proposed to construct hydrophilic CP nanoparticles (CP NPs), while endowing the CP NPs with redox activity and biocompatibility. This is a universal strategy applicable for a series of CPs, including polyaniline, polypyrrole, and poly(3,4-ethylenedioxythiophene). The catechol/quinone contained sulfonated lignin (LS) was doped into various CPs to form CP/LS NPs with hydrophilicity, conductivity, and redox activity. These CP/LS NPs were used as versatile nanofillers to prepare the conductive hydrogels with long-term adhesiveness. The CP/LS NPs-incorporated hydrogels have a good conductivity because of the uniform distribution of the hydrophilic NPs in the hydrogel network, forming a well-connected electric path. The hydrogel exhibits long-term adhesiveness, which is attributed to the mussel-inspired dynamic redox balance of catechol/quinone groups on the CP/LS NPs. This conductive and adhesive hydrogel shows good electroactivity and biocompatibility and therefore has broad applications in electrostimulation of tissue regeneration and implantable bioelectronics. [ABSTRACT FROM AUTHOR]

2D conductive nanosheets are central to electronic applications because of their large surface areas and excellent electronic properties. However, tuning the multifunctions and hydrophilicity of conductive nanosheets are still challenging. Herein, a green strategy is developed for fabricating conductive, redox‐active, water‐soluble nanosheets via the self‐assembly of poly(3,4‐ethylenedioxythiophene) (PEDOT) on the polydopamine‐reduced and sulfonated graphene oxide (PSGO) template. The conductivity and hydrophilicity of nanosheets are highly improved by PSGO. The nanosheets are redox active due to the abundant catechol groups and can be used as versatile nanofillers in developing conductive and adhesive hydrogels. The nanosheets create a mussel‐inspired redox environment inside the hydrogel networks and endow the hydrogel with long‐term and repeatable adhesiveness. This hydrogel is biocompatible and can be implanted for biosignals detection in vivo. This mussel‐inspired strategy for assembling 2D nanosheets can be adapted for producing diverse multifunctional nanomaterials, with various potential applications in bioelectronics. [ABSTRACT FROM AUTHOR]

Background: Circular RNAs (circRNAs), a novel class of noncoding RNAs, have recently drawn much attention in the pathogenesis of human cancers. However, the role of circRNAs in esophageal squamous cell carcinoma (ESCC) remains unclear. In this study, we aimed to identify novel circRNAs that regulate ESCC progression and explored their regulatory mechanisms and clinical significance in ESCC. Methods: Differentially expressed circRNAs between ESCC and paired adjacent normal tissues were identified using microarrays. The effects of a specific differentially expressed circRNA (circGSK3β) on tumor progression were explored in vitro and in vivo. Plasma samples from patients with ESCC, benign lesions and healthy controls were subjected to droplet digital PCR (ddPCR) analyses for circGSK3β, and the detection rates of plasma circGSK3β for ESCC were investigated. Results: We demonstrated that upregulated expression of circGSK3β was positively associated with advanced clinical stage and poor outcome in patients with ESCC. We further revealed that circGSK3β promoted ESCC cell migration and invasion via direct interaction with GSK3β and inhibiting GSK3β activity, providing a novel mechanism of circRNA in cancer progression. Importantly, we identified that circGSK3β expression in plasma was a biomarker for detection of ESCC and early stage of ESCC with the area under curve (AUC) of 0.782 and 0.793, respectively. Conclusions: CircGSK3β exerts critical roles in promoting ESCC metastasis and may serve as a novel therapeutic target for ESCC patients. The plasma level of circGSK3β have potential to serve as a novel diagnostic and prognostic biomarker for ESCC detection. [ABSTRACT FROM AUTHOR]

• Combination of experimental study and DFT calculation found that F− ions stabilized the Sr-doped HA crystals. • Sr/F-codoped HA showed excellent antibacterial activities against Streptococcus mutans. • An appropriate level of Sr doping caused the optimal osteogenic properties for the Sr/F-codoped HA. Multiple ions codoping may effectively modulate physicochemical and biological properties of hydroxyapatite (HA) for diverse biomedical applications. This study synthesized strontium (Sr)-, fluorine (F)- doped, and Sr/F-codoped HA nanoparticles by a hydrothermal method, and investigated the effect of ion doping on characteristics of HA, including crystallinity, crystal size, lattice parameters, and substitution sites by experiments and simulation with density functional theory (DFT) methods. It was found that, Sr doping increased the lattice parameters of HA whereas F doping decreased these parameters. Additionally, F doping enhanced the structural stability of the Sr-doped HA. F doping created excellent antibacterial properties to effectively inhibit growth of Streptococcus mutans. An appropriate Sr doping level endowed HA with optimum osteogenic ability to promote osteoblastic differentiation of bone marrow stem cells. These suggest that, Sr/F codoping is an effective approach to synthesizing HA-based materials with both antibacterial and osteogenic properties. More broadly, HA nanomaterials with specific characteristics may be designed for meeting diverse requirements from biomedical applications. [ABSTRACT FROM AUTHOR]

Antibacterial hydrogel has received extensive attention in soft tissue repair, especially preventing infections those associated with impaired wound healing. However, it is challenging in developing an inherent antibacterial hydrogel integrating with excellent cell affinity and superior mechanical properties. Inspired by the mussel adhesion chemistry, a contact‐active antibacterial hydrogel is proposed by copolymerization of methacrylamide dopamine (MADA) and 2‐(dimethylamino)ethyl methacrylate and forming an interpenetrated network with quaternized chitosan. The reactive catechol groups of MADA endow the hydrogel with contact intensified bactericidal activity, because it increases the exposure of bacterial cells to the positively charged groups of the hydrogel and strengthens the bactericidal effect. MADA also maintains the good adhesion of fibroblasts to the hydrogel. Moreover, the hybrid chemical and physical cross‐links inner the hydrogel network makes the hydrogel strong and tough with good recoverability. In vitro and in vivo tests demonstrate that this tough and contact‐active antibacterial hydrogel is a promising material to fulfill the dual functions of promoting tissue regeneration and preventing bacterial infection for wound‐healing applications. A mussel‐inspired, cell friendly, contact‐active antibacterial hydrogel is fabricated by copolymerization of methacrylamide dopamine and 2‐(dimethylamino)ethyl methacrylate and forming an interpenetrated network with quaternized chitosan. This hydrogel is tough and recoverable because of the hybrid chemical and physical cross‐links inside the hydrogel network. The hydrogel is a potent material to prevent bacterial infection for wound‐healing applications. [ABSTRACT FROM AUTHOR]

Due to low charge separation efficiency and poor stability, it is usually difficult for single-component photocatalysts such as graphitic carbon nitride (g-C3N4) and silver chromate (Ag2CrO4) to fulfill photocatalytic hydrogen production efficiently. Z-scheme charge transport mechanism that mimics the photosynthesis in nature is an effective way to solve the above problems. Inspired by photosynthesis, we report Ag2CrO4 nanoparticles-decorated g-C3N4 nanosheet as an efficient photocatalyst for hydrogen evolution reaction (HER) with methanol as sacrificial agent. The formation of Z-scheme g-C3N4/Ag2CrO4 nanosheets photocatalysts could inhibit the recombination of photogenerated electron-hole pairs, promote the generation of hydrogen by photosplitting of water. The experiment results indicate that g-C3N4/Ag2CrO4 nanocomposites present enhanced photocatalytic activity and stability in the H2 evolution of water splitting. And the nanocomposites g-C3N4/Ag2CrO4(23.1%) show the 14 times HER efficiency compared to that of bare g-C3N4. [ABSTRACT FROM AUTHOR]

In the experiment of inertial confinement fusion, soft X-ray spectrum unfolding can provide important information to optimize the design of the laser and target. As the laser beams increase, there are limited locations for installing detection channels to obtain measurements, and the soft X-ray spectrum can be difficult to recover. In this paper, a novel recovery method of soft X-ray spectrum unfolding based on compressive sensing is proposed, in which (1) the spectrum recovery is formulated as a problem of accurate signal recovery from very few measurements (i.e., compressive sensing), and (2) the proper basis atoms are selected adaptively over a Legendre orthogonal basis dictionary with a large size and Lasso regression in the sense of ℓ1 norm, which enables the spectrum to be accurately recovered with little measured data from the limited detection channels. Finally, the presented approach is validated with experimental data. The results show that it can still achieve comparable accuracy from only 8 spectrometer detection channels as it has previously done from 14 detection channels. This means that the presented approach is capable of recovering spectrum from the data of limited detection channels, and it can be used to save more space for other detectors. [ABSTRACT FROM AUTHOR]