137 results on '"Weiss, Nora"'
Search Results
102. Besonderheiten beim Bau der Oberflächenabdichtung der Deponie Hannover - genehmigungsrechtliche Besonderheiten - geologische Herausforderungen
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Vielhaber, Beate, Weiss, Nora, and Nolle, Dieter
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- 2013
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103. Cochlear and vestibular volumes in inner ear malformation.
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Breitsprecher, Tabita, Bächinger, David, Volkenstein, Stefan, Mlynski, Robert, Dazert, Stefan, Lagner, Sören, and Weiss, Nora
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- 2023
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104. Volumen von Cochlea und Vestibularorgan bei Innenohrmalformationen.
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Breitsprecher, Tabita, Bächinger, David, Volkenstein, Stefan, Mlynski, Robert, Dazert, Stefan, Lagner, Sören, and Weiss, Nora
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- 2023
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105. Investigating characteristics of health-related quality of life in different types of chronic middle ear disease
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chinger, David B, primary, Grossmann, Wilma, additional, Mlynski, Robert, additional, and Weiss, Nora, additional
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106. Maskierung des Gegenohres bei der Sprachaudiometrie im Freifeld -- Wirksamkeit von Gehörgangs- und Kapselgehörschutz vs. Maskierungsrauschen.
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Großmann, Wilma, Weiss, Nora Magdalena, Ehrt, K., Dahl, R., and Mlynski, R.
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SPEECH audiometry , *EAR canal , *MASKING (Psychology) , *HEARING protection - Published
- 2017
107. Cochlear and Vestibular Volumes in Inner Ear Malformations
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Tabita M. Breitsprecher, Alexander Pscheidl, David Bächinger, Stefan Volkenstein, Anandhan Dhanasingh, Vincent Van Rompaey, Robert Mlynski, Stefan Dazert, Paul Van de Heyning, Sönke Langner, Peter Roland, Nora M. Weiss, University of Zurich, and Weiss, Nora M
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Hearing Loss, Sensorineural ,Reproducibility of Results ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Cochlear Implantation ,Sensory Systems ,Cochlea ,Vestibular Aqueduct ,2809 Sensory Systems ,2733 Otorhinolaryngology ,2728 Neurology (clinical) ,Otorhinolaryngology ,Humans ,Human medicine ,Vestibule, Labyrinth ,Neurology (clinical) ,Retrospective Studies - Abstract
Objective A “gold standard” for quantitatively diagnosing inner ear malformations (IEMs) and a consensus on normative measurements are lacking. Reference ranges and cutoff values of inner ear dimensions may add in distinguishing IEM types. This study evaluates the volumes of the cochlea and vestibular system in different types of IEM. Study Design Retrospective cohort. Setting Tertiary academic center. Patients High-resolution CT scans of 115 temporal bones (70 with IEM; cochlear hypoplasia [CH]; n = 19), incomplete partition (IP) Types I and III (n = 16), IP Type II with an enlarged vestibular aqueduct (Mondini malformation; n = 16), enlarged vestibular aqueduct syndrome (n = 19), and 45 controls. Interventions Volumetry by software-based, semiautomatic segmentation, and 3D reconstruction. Main Outcome Measures Differences in volumes among IEM and between IEM types and controls; interrater reliability. Results Compared with controls (mean volume, 78.0 mm3), only CH showed a significantly different cochlear volume (mean volume, 30.2 mm3; p < 0.0001) among all types of IEM. A cutoff value of 60 mm3 separated 100% of CH cases from controls. Compared with controls, significantly larger vestibular system volumes were found in Mondini malformation (mean difference, 22.9 mm3; p = 0.009) and IP (mean difference, 24.1 mm3; p = 0.005). In contrast, CH showed a significantly smaller vestibular system volume (mean difference, 41.1 mm3; p < 0.0001). A good interrater reliability was found for all three-dimensional measurements (ICC = 0.86–0.91). Conclusion Quantitative reference values for IEM obtained in this study were in line with existing qualitative diagnostic characteristics. A cutoff value less than 60 mm3 may indicate an abnormally small cochlea. Normal reference values for volumes of the cochlea and vestibular system may aid in diagnosing IEM.
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- 2022
108. Allogenes und autologes Material führt bei Mastoidhöhlenobliteration zu vergleichbaren Rezidivraten
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Nora M Weiss, Robert Mlynski, Jannik Botzen, Hans Edgar Bernd, Torben Stallbaum, David Bächinger, Wilma Großmann, University of Zurich, and Weiss, Nora
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Gynecology ,medicine.medical_specialty ,business.industry ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,03 medical and health sciences ,2733 Otorhinolaryngology ,0302 clinical medicine ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Medicine ,030223 otorhinolaryngology ,business ,Mastoid cavity - Abstract
Zusammenfassung Einleitung Bei symptomatischen Mastoidhöhlen nach Ohroperationen besteht die Therapie der Wahl in der chirurgischen Verkleinerung. Hierbei stehen verschiedene Methoden und Materialien zur Obliteration zur Verfügung. Allogenes Material ist leicht verfügbar, kann jedoch zu Wundinfektionen aufgrund von Abstoßungsreaktionen, Granulationen und Entzündungsreaktionen führen, weshalb autologes Material aufgrund seiner guten Biokompatibilität häufig bevorzugt wird. Ziel dieser Studie war es, die Langzeitergebnisse von Patienten nach Mastoidhöhlenobliteration mit allogenem und autologem Material im Hinblick auf das Auftreten von Rezidivcholesteatomen, die Anzahl der Revisionsoperationen und den Einfluss der Operation auf die Lebensqualität zu vergleichen. Methoden Patienten, die sich einer Mastoidhöhlenobliteration mit dem allogenen Material Hydroxylapatit-Matrix (HMM) unterzogen, wurden retrospektiv in die Studie eingeschlossen. In einem prospektiven Studienteil wurden Patienten eingeschlossen, welche sich einer Mastoidhöhlenobliteration mit autologem Rekonstruktionsmaterial (AutoM) unterzogen. Bei allen Patienten wurde neben einer ausführlichen Aktenanalyse eine Reintonaudiometrie durchgeführt und bei der postoperativen Untersuchung das Zürcher Mittelohrinventar (Zurich Chronic Middle Ear Inventory [ZCMEI-21]) zur Erhebung der gesundheitsbezogenen, krankheitsspezifischen Lebensqualität ausgefüllt. Ergebnisse Insgesamt wurden 22 Patienten mit einem durchschnittlichen Alter von 56,9 Jahren (SD 18,7 Jahre) und HMM (mittleres Nachuntersuchungsintervall: 88,3 Monate; SD 21,9 Monate) sowie 25 Patienten mit einem Durchschnittsalter von 52,4 Jahren (SD 13,7 Jahre) und AutoM (mittleres Nachuntersuchungsintervall: 13,5 Monate; SD 9,5 Monate) in die Studie eingeschlossen. Die audiologische Revisionsfreiheit lag nach einem Jahr für HMM bei 100% und für AutoM bei 85%. Die Rezidivfreiheit lag nach einem Jahr für HMM bei 95% und für AutoM bei 100%. Die Gruppen unterschieden sich weder hinsichtlich des postoperativen Hörergebnisses noch der postoperativen Lebensqualität. Diskussion Die Obliteration von Mastoidhöhlen ist eine chirurgische Herausforderung. Es zeigte sich kein relevanter Unterschied zwischen den verwendeten Materialien im Hinblick auf die Rezidivrate, das Hören und die Lebensqualität über den für beide Gruppen beobachteten Zeitraum von 13,5 Monaten. Die oft fehlende subjektive Symptomatik zusammen mit der hohen Rate an Rezidivcholesteatomen und Revisionsindikationen unterstreicht die Notwendigkeit einer regelmäßigen klinischen Nachsorge inklusive der Ohrmikroskopie bei chronischen Mittelohrerkrankungen und lässt regelmäßige Nachuntersuchungen dringend empfehlen.
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- 2021
109. Characteristics of health-related quality of life in different types of chronic middle ear disease
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Wilma Großmann, Nora M Weiss, David Bächinger, Robert Mlynski, University of Zurich, and Weiss, Nora M
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Adult ,Male ,medicine.medical_specialty ,Hearing loss ,Ear, Middle ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Mastoid ,03 medical and health sciences ,Tympanoplasty ,0302 clinical medicine ,Quality of life ,Internal medicine ,Vertigo ,otorhinolaryngologic diseases ,medicine ,Humans ,Longitudinal Studies ,Prospective Studies ,030223 otorhinolaryngology ,Retrospective Studies ,Cholesteatoma, Middle Ear ,medicine.diagnostic_test ,biology ,business.industry ,Cholesteatoma ,General Medicine ,medicine.disease ,biology.organism_classification ,humanities ,Otitis Media ,Treatment Outcome ,2733 Otorhinolaryngology ,medicine.anatomical_structure ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Chronic Disease ,Quality of Life ,Middle ear ,Female ,Neurosurgery ,medicine.symptom ,Audiometry ,business - Abstract
Different types of chronic middle ear disease (CMED) present with differing severity of single symptoms, such as discharge, vertigo or hearing loss, which impair health-related quality of life (HRQoL). Here, we aimed to (i) investigate characteristics of HRQoL and (ii) evaluate the association between HRQoL and hearing among different types of CMED. In this prospective longitudinal cohort study, we included adult patients undergoing surgical treatment for CMED. Primary outcomes included HRQoL assessed by the Zurich Chronic Middle Ear Inventory (ZCMEI-21) and hearing assessed by pure-tone audiometry. In the included 108 patients (51% females), CMED were chronic otitis media (COM) with (n = 46) or without (n = 22) cholesteatoma, persistent mastoid cavity (with [n = 15] or without [n = 10] recurrent cholesteatoma), revision ossiculoplasty for hearing restoration (n = 14), and postinflammatory meatal fibrosis (n = 1). Preoperatively, the mean ZCMEI-21 score showed statistically significant differences among different types of CMED (p = 0.007) with persistent mastoid cavity without cholesteatoma exhibiting the highest score (34.1, SD 7.7) indicating poor HRQoL. At a mean follow-up period of 183 days, no statistically significant differences in the ZCMEI-21 scores among different types of CMED were observed (p = 0.67). This study objectifies differences in HRQoL among different types of CMED. In patients with indication for functional surgery only, e.g., persistent mastoid cavity without cholesteatoma, the worst HRQoL was observed. Yet, in these types of CMED, HRQoL guides decision for treatment. Moreover, differences in HRQoL among different types of CMED were not closely associated with hearing, but largely depended on other symptoms, such as discharge or vertigo.
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- 2020
110. Mastoid cavity obliteration leads to a clinically significant improvement in health-related quality of life
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Robert Mlynski, David Bächinger, Jannik Botzen, Nora M Weiss, Wilma Großmann, University of Zurich, and Weiss, Nora M
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Male ,medicine.medical_specialty ,Chronic middle ear disease ,Mastoidectomy ,medicine.medical_treatment ,Otology ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Mastoid ,Tympanoplasty ,Bone conduction ,Quality of life ,medicine ,Humans ,Prospective Studies ,Chronic otitis media ,Cholesteatoma ,Obliteration ,Mastoid cavity ,Retrospective Studies ,ZCMEI-21 ,Cholesteatoma, Middle Ear ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Surgery ,Treatment Outcome ,2733 Otorhinolaryngology ,medicine.anatomical_structure ,Otorhinolaryngology ,Quality of Life ,Middle ear ,Female ,Neurosurgery ,business - Abstract
Objective To assess the change in health-related quality of life (HRQoL) in patients undergoing mastoid cavity obliteration. Methods Patients who had undergone canal wall-down mastoidectomy for chronic otitis media with creation of a persistent mastoid cavity and underwent revision tympanomastoid surgery including mastoid cavity obliteration using autologous material were included. Audiological measurements including air conduction (AC) and bone conduction (BC) pure-tone averages (PTA) and the air–bone gap (ABG) were assessed. Health-related Quality of Life (HRQoL) was assessed by the Zurich Chronic Middle Ear Inventory (ZCMEI-21) pre- and postoperatively. Results A total of 25 patients (16 females and 9 males; mean age 51.6 years, 14 right and 11 left ears) were included. Patients were reexamined after a mean follow-up period of 9.2 months (SD = 6.5) after obliteration of the mastoid cavity. Compared to the preoperative visit, patients showed a significantly reduced AC PTA at the postoperative visit (mean difference: − 4.1; SD = 10.4, p = 0.045). The mean ZCMEI-21 score changed from 31.7 (SD = 14.5) preoperatively to 17.4 (SD = 15.1) postoperatively (mean difference: − 14.3; SD = 19.1; p = 0.0002). The mean ZCMEI-21 score changes were neither correlated to the AC PTA shift (p = 0.60) nor to the ABG shift (p = 0.66). Conclusions This is the first study reporting a highly significant and clinically important improvement in HRQoL after mastoid cavity obliteration in a prospective setting. The improvement in HRQoL was not correlated to the hearing improvement. As a clinical implication, we provide evidence for a substantial subjective benefit of the surgical obliteration of a symptomatic mastoid cavity and, therefore, encourage this surgical procedure.
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- 2020
111. Comparison of two disease‑specific instruments assessing health-related quality of life in patients with chronic otitis media
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Theresa Langanke, Nora M Weiss, David Bächinger, S Lailach, Robert Mlynski, Marcus Neudert, University of Zurich, and Weiss, Nora M
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Adult ,medicine.medical_specialty ,Psychometrics ,COMOT-15 ,Concurrent validity ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Otology ,Correlation ,03 medical and health sciences ,0302 clinical medicine ,Cronbach's alpha ,Quality of life ,Vertigo ,Surveys and Questionnaires ,medicine ,Humans ,Gender difference ,030223 otorhinolaryngology ,Cholesteatoma ,ZCMEI-21 ,biology ,business.industry ,Questionnaire ,Reproducibility of Results ,General Medicine ,Middle Aged ,biology.organism_classification ,medicine.disease ,Test (assessment) ,Otitis Media ,2733 Otorhinolaryngology ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Chronic Disease ,Physical therapy ,Quality of Life ,Hearing perception ,business - Abstract
Purpose Evaluating the current health state in chronic otitis media (COM), audiologic results are complemented by subjective outcomes, such as health-related quality of life (HRQoL). Two disease-specific instruments assessing HRQoL in COM in German-speaking patients exist, i.e., the chronic otitis media outcome test (COMOT-15) and the Zurich chronic middle ear inventory (ZCMEI-21). Since the psychometric properties of these questionnaires in a concurrent application are unknown, the aim of this study was to compare the COMOT-15 and the ZCMEI-21. Methods HRQoL was assessed in adult COM patients using the COMOT-15 and the ZCMEI-21. Psychometric properties were determined, including response distribution, concurrent validity, internal consistency, correlation to hearing and gender differences. Results In 173 patients (mean age 51.5 years), both questionnaires showed normally distributed scores without strong floor and ceiling effects. The total scores and subscores of both questionnaires exhibited satisfactory internal consistency (Cronbach’s α 0.7–0.9) with the exception of the COMOT-15 hearing subscore (α = 0.94) and the ZCMEI-21 medical resource subscore (α = 0.66). Fair correlations between the air conduction pure-tone average and the total scores were found (COMOT-15: r = 0.36, p r = 0.34, p Conclusion In the first study comparing the COMOT-15 and the ZCMEI-21, both questionnaires exhibited satisfactory psychometric properties with several subtle differences. The COMOT-15 has a strong focus on hearing with a probably redundant content of the hearing subscore and may be suited for hearing-focused research questions. The ZCMEI-21 provides a comprehensive assessment of the COM symptom complex and may therefore also be used in research settings, where ear discharge, vertigo or pain should be covered.
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- 2020
112. Mapping the ChOLE classification to hearing outcomes and disease-specific health-related quality of life
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Christof Röösli, Nora M Weiss, Alexander M. Huber, David Bächinger, Robert Mlynski, Hans Edgar Bernd, Adrian Rrahmani, University of Zurich, and Weiss, Nora M
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Quality of life ,Disease specific ,medicine.medical_specialty ,Staging ,medicine.medical_treatment ,Ear, Middle ,Otology ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Tympanoplasty ,Hearing ,Internal medicine ,otorhinolaryngologic diseases ,medicine ,Humans ,Stage (cooking) ,Cholesteatoma ,Retrospective Studies ,Health related quality of life ,ZCMEI-21 ,Cholesteatoma, Middle Ear ,business.industry ,ChOLE classification ,Hearing Tests ,General Medicine ,Middle Aged ,medicine.disease ,Treatment Outcome ,2733 Otorhinolaryngology ,Otorhinolaryngology ,Neurosurgery ,business - Abstract
Objectives To investigate the association between the “ChOLE” classification, hearing outcomes and disease-specific health-related quality of life (HRQoL). Methods In two tertiary referral centers, patients requiring primary or revision surgery for cholesteatoma were assessed for eligibility. Audiometric assessment was performed pre- and postoperatively. The ChOLE classification was determined intraoperatively and via the preoperative CT scan. HRQoL was assessed pre- and postoperatively using the Zurich Chronic Middle Ear Inventory (ZCMEI-21). Results A total of 87 patients (mean age 45.2 years, SD 16.2) were included in this study. ChOLE stage I cholesteatoma was found in 8 (9%), stage II cholesteatoma was found in 65 (75%), and stage III cholesteatoma was found in 14 (16%) patients. Postoperatively, the mean air–bone gap (0.5, 1, 2, 3 kHz) was significantly smaller than before surgery (14.3 dB vs. 23.0 dB; p = 0.0007). The mean ZCMEI-21 total score significantly decreased after surgery (26.8 vs. 20.7, p = 0.004). No correlation between the ZCMEI-21 total score and both the ChOLE stage and the extent of the cholesteatoma (ChOLE subdivision “Ch”) was found. A trend towards worse HRQoL associated with a poorer status of the ossicular chain (ChOLE subdivision “O”) was observed. The audiometric outcomes were not associated with the extent of the cholesteatoma. The ChOLE subdivision describing the ossicular status showed a strong association with the pre- and postoperative air conduction (AC) thresholds. Further, the ZCMEI-21 total score and its hearing subscore correlated with the AC thresholds. Conclusion The ChOLE classification does not show a clear association with HRQoL measured by the ZCMEI-21. The HRQoL neither seems to be associated with the extent of the disease nor with the ossicular chain status. Yet, surgical therapy significantly improved HRQoL by means of reduced ZCMEI-21 total scores, which were strongly associated with the AC thresholds. Intraoperative assessment of a cholesteatoma using the ChOLE classification and HRQoL complement each other and provide useful information.
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- 2020
113. Establishing the minimal clinically important difference (MCID) of the Zurich Chronic Middle Ear Inventory (ZCMEI-21) in patients treated for chronic middle ear disease
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David Bächinger, Nora M Weiss, Robert Mlynski, University of Zurich, and Weiss, Nora M
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Adult ,Male ,Quality of life ,medicine.medical_specialty ,Longitudinal study ,Minimal Clinically Important Difference ,Ear, Middle ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Otology ,MCID ,HRQoL ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,In patient ,Longitudinal Studies ,Patient Reported Outcome Measures ,Prospective Studies ,Chronic otitis media ,030223 otorhinolaryngology ,COM ,Aged ,business.industry ,Minimal clinically important difference ,Middle ear disease ,General Medicine ,Middle Aged ,humanities ,Otitis Media ,2733 Otorhinolaryngology ,medicine.anatomical_structure ,Treatment Outcome ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Chronic Disease ,Middle ear ,Physical therapy ,Female ,Neurosurgery ,business ,Otologic Surgical Procedures - Abstract
Aim To determine the minimal clinically important difference (MCID) of the Zurich Chronic Middle Ear Inventory (ZCMEI-21), a questionnaire assessing health-related quality of life (HRQoL) in chronic otitis media (COM). Methods In this longitudinal study, 103 patients completed the ZCMEI-21 before and after surgery for chronic otitis media. An anchor-based method including a global rating of change (GRC) was used to assess the MCID of the ZCMEI-21. Results A total of 103 patients were included. The mean preoperative and postoperative ZCMEI-21 scores were 28.6 (SD 13.6), and 21.8 (SD 12.8), respectively. The mean change was 6.8 (SD 0.8; p r = − 0.5; p Conclusions Knowledge of values indicating a clinically relevant change in patient-reported outcome measures is important when interpreting effects of different treatment modalities. This is the first study assessing the MCID of a questionnaire measuring HRQoL in COM, i.e. the ZCMEI-21. We recommend a MCID of 5 in COM patients undergoing surgical treatment. This information substantially increases the usefulness of the ZCMEI-21 as an outcome measure in COM as changes can be assessed with regard to their clinical meaningfulness.
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- 2019
114. Open Mastoid Cavity Obliteration With a High-Porosity Hydroxyapatite Ceramic Leads to High Rate of Revision Surgery and Insufficient Cavity Obliteration
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Sarah Zonnur, Sönke Langner, Sophie Stecher, T Schuldt, David Bächinger, Sebastian P. Schraven, Robert Mlynski, Nora M Weiss, University of Zurich, and Weiss, Nora M
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Adult ,Male ,Reoperation ,medicine.medical_specialty ,Mastoidectomy ,Clinical Neurology ,Ear, Middle ,610 Medicine & health ,10045 Clinic for Otorhinolaryngology ,Mastoid ,Cohort Studies ,03 medical and health sciences ,2809 Sensory Systems ,0302 clinical medicine ,Tympanoplasty ,medicine ,Humans ,030223 otorhinolaryngology ,Ear Diseases ,Mastoid cavity ,Retrospective Studies ,High rate ,medicine.diagnostic_test ,business.industry ,Granulation tissue ,Cholesteatoma ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Sensory Systems ,Surgery ,medicine.anatomical_structure ,2733 Otorhinolaryngology ,2728 Neurology (clinical) ,Cross-Sectional Studies ,Durapatite ,Otorhinolaryngology ,Middle ear ,Quality of Life ,Female ,Neurology (clinical) ,business ,Porosity ,030217 neurology & neurosurgery ,Cohort study - Abstract
Objective: To assess long-term results and present experience with a high-porosity hydroxyapatite ceramic for obliterating large open mastoid cavities. Study-Design: Cross-sectional cohort study. Setting: Tertiary academic referral center. Patients: All patients who underwent tympanomastoid surgery for chronic middle ear disease or revision surgery with reduction of an open mastoid cavity using a highly porous hydroxyapatite matrix material (HMM) between May 2005 and June 2013 were assessed for eligibility. Twenty three patients (56.9 ± 18.3 yr) were included. Intervention: Primary middle ear surgery or revision surgery using a HMM. Main Outcome Measures: Pure-tone average, computed tomography (CT), and magnetic resonance imaging (MRI) to investigate osseoinduction, osseointegration and presence of cholesteatoma, current quality of life assessed by Zurich Chronic Middle Ear Inventory and change in quality of life post-intervention assessed by the Glasgow Benefit Inventory. Results: Patients were reexamined after a mean follow-up period of 88.3 months (SD 21.4 mo) after obliteration of the open mastoid cavity with HMM. Compared with visit 1, patients showed a significantly reduced ABG at visit 2 (29.22 dB ± 2.71 dB versus 12.77 dB ± 3.46 dB). CT scan was carried out in 21 patients (91%) patients and 17 patients (74%) underwent MRI. Revision surgery was required in a total of 17 cases (74%). In four patients recurrent cholesteatoma was found at follow up. Conclusions: Poor cavity obliteration, a high rate of revision surgery and difficult differentiation between recurrent cholesteatoma and granulation tissue in CT scan was observed.
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- 2019
115. [Correction: Congenital malformations of the inner ear - CT, DVT and MR Imaging].
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Langner S and Weiss NM
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Competing Interests: Erklärung zu finanziellen Interessen Forschungsförderung erhalten: nein; Honorar/geldwerten Vorteil für Referententätigkeit erhalten: nein; Bezahlter Berater/interner Schulungsreferent/Gehaltsempfänger: nein; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an Firma (Nicht‐Sponsor der Veranstaltung): nein; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an Firma (Sponsor der Veranstaltung): nein Erklärung zu nichtfinanziellen Interessen S. Langner: Vorsitzender AG Kopf-Hals-Radiologie der Deutschen Röntgengesellschaft
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- 2024
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116. [Congenital malformations of the inner ear - CT, DVT and MR Imaging].
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Langner S and Weiss NM
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- Humans, Venous Thrombosis diagnostic imaging, Diagnosis, Differential, Infant, Newborn, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Ear, Inner abnormalities, Ear, Inner diagnostic imaging, Tomography, X-Ray Computed
- Abstract
Competing Interests: Erklärung zu finanziellen Interessen Forschungsförderung erhalten: nein; Honorar/geldwerten Vorteil für Referententätigkeit erhalten: nein; Bezahlter Berater/interner Schulungsreferent/Gehaltsempfänger: nein; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an Firma (Nicht‐Sponsor der Veranstaltung): nein; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an Firma (Sponsor der Veranstaltung): nein Erklärung zu nichtfinanziellen Interessen S. Langner: Vorsitzender AG Kopf-Hals-Radiologie der Deutschen Röntgengesellschaft
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- 2024
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117. Evaluation of an impedance-based method to monitor the insertion of the electrode array during cochlear implantation.
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Gottfried TM, Galeazzi P, Föger A, Dejaco D, Tröger A, Fischer N, Innerhofer V, Di Trapani F, Weiss N, Seebacher J, Dierker A, and Schmutzhard J
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- Humans, Male, Female, Middle Aged, Adult, Aged, Child, Child, Preschool, Adolescent, Electrodes, Implanted, Evoked Potentials, Auditory physiology, Young Adult, Monitoring, Intraoperative methods, Monitoring, Intraoperative instrumentation, Cochlear Implantation methods, Electric Impedance, Feasibility Studies, Cochlear Implants
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Purpose: Cochlear implantation is a prevalent remedy for severe-to-profound hearing loss. Optimising outcomes and hearing preservation, and minimising insertion trauma, require precise electrode placement. Objective monitoring during the insertion process can provide valuable insights and enhance surgical precision. This study assesses the feasibility and performance of an impedance-based method for monitoring electrode insertion, compared to the surgeon's feedback., Methods: The study utilised the Insertion Monitoring Tool (IMT) research software, allowing for real-time measurement of impedance and evoked compound action potential (eCAP) during electrode insertion in 20 patient implantations. This enabled an impedance-based method to continuously assess the status of each electrode during the insertion process. The feasibility and performance was evaluated and compared to the surgeon's feedback approach. eCAP measurements focused merely on feasibility without searching specific responses., Results: The IMT demonstrated feasibility in measuring real-time impedances and eCAP during the insertion of the electrode array. The impedance-based method exhibited potential for accurately monitoring the insertion depth with a high success rate. However, further development is needed to improve the number of usable contacts., Conclusions: Objective monitoring with the impedance-based method shows promise as a valuable tool to enhance the precision of cochlear implant electrode insertion respecting insertion distance estimation. The IMT research software proved feasible in recording real-time impedances and eCAP during electrode insertion. While this impedance-based method exhibits high success rates, further improvements are required to optimise the number of usable contacts. This study highlights the potential of objective monitoring techniques to enhance cochlear implantation outcomes., (© 2024. The Author(s).)
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- 2024
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118. [Virtual DEGUM-certified course in the head and neck region-a useful complement to conventional course formats?]
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Hillebrand G, Gartmeier M, Weiss N, Engelmann L, Stenzl A, Johnson F, and Hofauer B
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- Humans, Ultrasonography, Neck diagnostic imaging, Curriculum, Head diagnostic imaging, Medicine
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Background: Training in clinical ultrasound has become highly relevant for working as an otorhinolaryngologist. While there is a high demand for standardized and certified training courses, until recently, there was no possibility to attend web-based and exclusively virtual head and neck ultrasound courses certified by the Deutsche Gesellschaft für Ultraschall in der Medizin (DEGUM; German Society for Ultrasound in Medicine)., Objective: The aim of this study was to provide a qualitative and semi-quantitative analysis of the first purely virtual DEGUM-certified head and neck ultrasound courses., Materials and Methods: In 2021, three purely web-based DEGUM-certified head and neck ultrasound courses were carried out and then qualitatively analyzed using questionnaires including an examination., Results: The purely virtual implementation of head and neck ultrasound courses proved to be a viable alternative to the conventional course format, with a high level of acceptance among the participants. The lack of practice among the participants remains a relevant criticism., Conclusion: A more dominant role of web-based and remote ultrasound training is likely and should be considered as an alternative depending on existing conditions. Nevertheless, acquisition of practical sonographic skills remains a major hurdle if courses are purely digital., (© 2024. The Author(s).)
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- 2024
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119. Comparing linear and non-linear models to estimate the appropriate cochlear implant electrode array length-are current methods precise enough?
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Weiss NM, Breitsprecher T, Wozniak M, Bächinger D, Völter C, Mlynski R, Van de Heyning P, Van Rompaey V, and Dazert S
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- Humans, Retrospective Studies, Cross-Sectional Studies, Nonlinear Dynamics, Cochlea diagnostic imaging, Cochlea surgery, Cochlear Implantation methods, Cochlear Implants
- Abstract
Purpose: In cochlear implantation with flexible lateral wall electrode arrays, a cochlear coverage (CC) range between 70% and 80% is considered ideal for optimal speech perception. To achieve this CC, the cochlear implant (CI) electrode array has to be chosen according to the individual cochlear duct length (CDL). Here, we mathematically analyzed the suitability of different flexible lateral wall electrode array lengths covering between 70% and 80% of the CDL., Methods: In a retrospective cross-sectional study preoperative high-resolution computed tomography (HRCT) from patients undergoing cochlear implantation was investigated. The CDL was estimated using an otosurgical planning software and the CI electrode array lengths covering 70-80% of the CDL was calculated using (i) linear and (ii) non-linear models., Results: The analysis of 120 HRCT data sets showed significantly different model-dependent CDL. Significant differences between the CC of 70% assessed from linear and non-linear models (mean difference: 2.5 mm, p < 0.001) and the CC of 80% assessed from linear and non-linear models (mean difference: 1.5 mm, p < 0.001) were found. In up to 25% of the patients none of the existing flexible lateral wall electrode arrays fit into this range. In 59 cases (49,2%) the models did not agree on the suitable electrode arrays., Conclusions: The CC varies depending on the underlying CDL approximation, which critically influences electrode array choice. Based on the literature, we hypothesize that the non-linear method systematically overestimates the CC and may lead to rather too short electrode array choices. Future studies need to assess the accuracy of the individual mathematical models., (© 2023. The Author(s).)
- Published
- 2024
- Full Text
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120. [The Bochum Temporal Bone Course - Part 6: Tympanomeatal flap, exostosis of external canal and reconstruction of the ossicular chain].
- Author
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Weiss NM, van Ackeren K, Volkenstein S, and Dazert S
- Subjects
- Humans, Temporal Bone surgery, Surgical Flaps, Retrospective Studies, Exostoses, Ossicular Prosthesis, Ossicular Replacement
- Abstract
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
- Published
- 2023
- Full Text
- View/download PDF
121. [The Bochum Temporal Bone Course - Part 5: Labyrinthectomy and preparation of the internal auditory canal].
- Author
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Weiss NM, van Ackeren K, Volkenstein S, and Dazert S
- Subjects
- Humans, Temporal Bone surgery, Petrous Bone, Ear, Inner surgery
- Abstract
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
- Published
- 2023
- Full Text
- View/download PDF
122. [The Bochum Temporal Bone Course - Part 4: Exposition of the facial nerve, posterior tympanotomy and facial nerve decompression].
- Author
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van Ackeren K, Weiss NM, Volkenstein S, and Dazert S
- Subjects
- Humans, Temporal Bone surgery, Tympanic Membrane, Middle Ear Ventilation, Decompression, Surgical, Facial Nerve surgery, Facial Paralysis surgery
- Abstract
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
- Published
- 2023
- Full Text
- View/download PDF
123. [Health-related quality of life in chronic otitis media-measurement methods and their application in surgical therapy].
- Author
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Bächinger D, Neudert M, Dazert S, Röösli C, Huber A, Mlynski R, and Weiss NM
- Subjects
- Humans, Quality of Life, Surveys and Questionnaires, Ear, Middle, Chronic Disease, Treatment Outcome, Otitis Media diagnosis, Otitis Media surgery, Otitis Media complications, Cholesteatoma, Middle Ear
- Abstract
Background: Chronic otitis media (COM) can lead to significant impairment of health-related quality of life (HRQoL) due to symptoms such as otorrhea, pain, hearing loss, tinnitus, or dizziness. A systematic assessment of HRQoL in COM is becoming increasingly important as it complements (semi-)objective outcome parameters in clinical practice and research. HRQoL is measured by means of patient-reported outcome measures (PROMs). There are two disease-specific validated PROMs available for COM in German-the Chronic Otitis Media Outcome Test (COMOT-15) and the Zurich Chronic Middle Ear Inventory (ZCMEI-21)-which have become increasingly popular in recent years., Objective: The purpose of this narrative review is to present the current state of research on measuring HRQoL in COM before and after surgical procedures., Results and Conclusion: Hearing is the most important factor influencing HRQoL in COM. Surgical procedures usually result in a clinically relevant improvement in HRQoL in COM with or without cholesteatoma. However, if cholesteatoma is present, its extent does not correlate with HRQoL. While HRQoL plays a secondary role in establishment of the indication for surgical therapy in COM with cholesteatoma, it plays an important role in terms of relative surgical indications, e.g., a symptomatic open mastoid cavity after resection of the posterior canal wall. We encourage the regular use of disease-specific PROMs preoperatively as well as during follow-up to assess HRQoL in COM in individual patients, in research, and in the context of quality monitoring., (© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
124. [The Bochum Temporal Bone Course - Part 3: Identification of the Semicircular Canals and Endolymphatic Sac Surgery].
- Author
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van Ackeren K, Weiss N, Volkenstein S, and Dazert S
- Subjects
- Humans, Semicircular Canals surgery, Temporal Bone surgery, Endolymphatic Sac surgery
- Abstract
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
- Published
- 2023
- Full Text
- View/download PDF
125. [The Bochum Temporal Bone Course - Part 2: Antrostomy and Mastoidectomy].
- Author
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van Ackeren K, Weiss N, Volkenstein S, and Dazert S
- Subjects
- Humans, Mastoid surgery, Mastoidectomy, Temporal Bone
- Abstract
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
- Published
- 2023
- Full Text
- View/download PDF
126. [The Bochum Temporal Bone Course - Part 1: How to set up your workstation].
- Author
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van Ackeren K, Weiss N, Volkenstein S, and Dazert S
- Abstract
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
- Published
- 2023
- Full Text
- View/download PDF
127. [Cochlear implantation - Adverse effects on the cochlea and the vestibular organ].
- Author
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Weiss N
- Subjects
- Humans, Acoustic Stimulation methods, Cochlea surgery, Hearing, Cochlear Implantation adverse effects, Cochlear Implantation methods, Cochlear Implants adverse effects
- Abstract
Cochlear implantation is the treatment of choice for patients with profound hearing loss and deafness. At the same time, inserting a cochlear implant (CI) leaves damage to the inner ear. The preservation of inner ear structure and function has become a central issue in CI surgery. The reasons for this are i) electroacoustic stimulation (EAS), i.e., the option of joint stimulation by a hearing aid and a CI; ii) an improved audiologic outcome in electric-only stimulation; iii) the preservation of structures and residual hearing for potential future therapy options; and iv) the avoidance of side effects, such as vertigo. The exact mechanisms that determine the extent of damage to the inner ear and which factors contribute to preservation of residual hearing are not yet fully understood. In addition to the surgical technique, electrode selection may play a role. This article provides an overview of what is known about the direct and indirect adverse effects of cochlear implantation on the inner ear, of the methods available to monitor inner ear function during cochlear implantation, and of the focus of future research on preservation of inner ear structure and function., Competing Interests: Erklärung zu finanziellen Interessen Forschungsförderung erhalten: ja, von einer anderen Institution (Pharma- oder Medizintechnikfirma usw.); Honorar/geldwerten Vorteil für Referententätigkeit erhalten: ja, von einer anderen Institution (Pharma- oder Medizintechnikfirma usw.); Bezahlter Berater/interner Schulungsreferent/Gehaltsempfänger: nein; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an im Bereich der Medizin aktiven Firma: nein; Patent/Geschäftsanteile/Aktien (Autor/Partner, Ehepartner, Kinder) an zu Sponsoren dieser Fortbildung bzw. durch die Fortbildung in ihren Geschäftsinteressen berührten Firma: nein Erklärung zu nichtfinanziellen Interessen Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
128. Volumetry improves the assessment of the vestibular aqueduct size in inner ear malformation.
- Author
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Weiss NM, Breitsprecher TM, Pscheidl A, Bächinger D, Volkenstein S, Dazert S, Mlynski R, Langner S, Roland P, and Dhanasingh A
- Subjects
- Humans, Reproducibility of Results, Retrospective Studies, Cochlea, Hearing Loss, Sensorineural, Vestibular Aqueduct diagnostic imaging, Vestibular Aqueduct abnormalities
- Abstract
Objectives: Enlarged vestibular aqueduct (EVA) is a common finding associated with inner ear malformations (IEM). However, uniform radiologic definitions for EVA are missing and various 2D-measurement methods to define EVA have been reported. This study evaluates VA volume in different types of IEM and compares 3D-reconstructed VA volume to 2D-measurements., Methods: A total of 98 high-resolution CT (HRCT) data sets from temporal bones were analyzed (56 with IEM; [cochlear hypoplasia (CH; n = 18), incomplete partition type I (IPI; n = 12) and type II (IPII; n = 11) and EVA (n = 15)]; 42 controls). VA diameter was measured in axial images. VA volume was analyzed by software-based, semi-automatic segmentation and 3D-reconstruction. Differences in VA volume between the groups and associations between VA volume and VA diameter were assessed. Inter-rater-reliability (IRR) was assessed using the intra-class-correlation-coefficient (ICC)., Results: Larger VA volumes were found in IEM compared to controls. Significant differences in VA volume between patients with EVA and controls (p < 0.001) as well as between IPII and controls (p < 0.001) were found. VA diameter at the midpoint (VA midpoint) and at the operculum (VA operculum) correlated to VA volume in IPI (VA midpoint: r = 0.78, VA operculum: r = 0.91), in CH (VA midpoint: r = 0.59, VA operculum: r = 0.61), in EVA (VA midpoint: r = 0.55, VA operculum: r = 0.66) and in controls (VA midpoint: r = 0.36, VA operculum: r = 0.42). The highest IRR was found for VA volume (ICC = 0.90)., Conclusions: The VA diameter may be an insufficient estimate of VA volume, since (1) measurement of VA diameter does not reliably correlate with VA volume and (2) VA diameter shows a lower IRR than VA volume. 3D-reconstruction and VA volumetry may add information in diagnosing EVA in cases with or without additional IEM., (© 2022. The Author(s).)
- Published
- 2023
- Full Text
- View/download PDF
129. Internal auditory canal volume in normal and malformed inner ears.
- Author
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Bächinger D, Breitsprecher TM, Pscheidl A, Dhanasingh A, Mlynski R, Dazert S, Langner S, and Weiss NM
- Subjects
- Humans, Reproducibility of Results, Retrospective Studies, Cochlea diagnostic imaging, Ear, Inner diagnostic imaging, Ear, Inner abnormalities, Hearing Loss, Sensorineural diagnostic imaging, Hearing Loss, Sensorineural surgery
- Abstract
Purpose: A narrow bony internal auditory canal (IAC) may be associated with a hypoplastic cochlear nerve and poorer hearing performances after cochlear implantation. However, definitions for a narrow IAC vary widely and commonly, qualitative grading or two-dimensional measures are used to characterize a narrow IAC. We aimed to refine the definition of a narrow IAC by determining IAC volume in both control patients and patients with inner ear malformations (IEMs)., Methods: In this multicentric study, we included high-resolution CT (HRCT) scans of 128 temporal bones (85 with IEMs: cochlear aplasia, n = 11; common cavity, n = 2; cochlear hypoplasia type, n = 19; incomplete partition type I/III, n = 8/8; Mondini malformation, n = 16; enlarged vestibular aqueduct syndrome, n = 19; 45 controls). The IAC diameter was measured in the axial plane and the IAC volume was measured by semi-automatic segmentation and three-dimensional reconstruction., Results: In controls, the mean IAC diameter was 5.5 mm (SD 1.1 mm) and the mean IAC volume was 175.3 mm
3 (SD 52.6 mm3 ). Statistically significant differences in IAC volumes were found in cochlear aplasia (68.3 mm3 , p < 0.0001), IPI (107.4 mm3 , p = 0.04), and IPIII (277.5 mm3 , p = 0.0004 mm3 ). Inter-rater reliability was higher in IAC volume than in IAC diameter (intraclass correlation coefficient 0.92 vs. 0.77)., Conclusions: Volumetric measurement of IAC in cases of IEMs reduces measurement variability and may add to classifying IEMs. Since a hypoplastic IAC can be associated with a hypoplastic cochlear nerve and sensorineural hearing loss, radiologic assessment of the IAC is crucial in patients with severe sensorineural hearing loss undergoing cochlear implantation., (© 2022. The Author(s).)- Published
- 2023
- Full Text
- View/download PDF
130. [Interactive intraoperative annotation of surgical landmarks in student education to support learning efficiency and motivation].
- Author
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van Bonn SM, Grajek JS, Schuldt T, Schraven SP, Schneider A, Rettschlag S, Oberhoffner T, Weiss NM, and Mlynski R
- Subjects
- Humans, Learning, Motivation, Pilot Projects, Students, Education, Medical, Students, Medical
- Abstract
Background: The development of technological innovations has not only changed social life and the healthcare system, but also affects medical education. The aim of this pilot study was to evaluate whether students, when observing a microsurgical procedure of the temporal bone, gain an additional understanding of the anatomical structures and surgical site when visualization is used that provides identical views for the surgeon and viewer in 3D., Materials and Methods: During regular attendance tutorials, students were randomly assigned to three different groups: control group, 2D group, or 3D group. Evaluation questionnaires and intraoperative student annotation of the surgical view were used to assess the subjective didactic value of different visualization formats and resultant learning experiences for the students., Results: A total of 47 students were included in the investigations during conventional attendance tutorials. The majority indicated a high added value of the 3D visualization in terms of method (70%) and vividness (80%) compared to the 2D group and self-study; 69% of the students fully agreed with the statement that 2D and 3D visualization increases learning motivation and is a very good way to improve recognition of anatomical topography and structures., Conclusion: New interactive visualization options in teaching promote learning efficiency and motivation among students. Especially 3D visualization and intraoperative annotation of the surgical view by the student is a useful didactic tool and increases the quality of clinical teaching. It supports the perception of anatomical topography and enables more focused surgical training., (© 2022. The Author(s).)
- Published
- 2022
- Full Text
- View/download PDF
131. [Eustachian tube dysfunction after cleft palate surgery : Use of the latest diagnostics].
- Author
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Weiss NM, Bennöhr F, Lenz JH, Mlynski R, and Rettschlag S
- Subjects
- Acoustic Impedance Tests, Adult, Child, Preschool, Humans, Surveys and Questionnaires, Cleft Palate diagnosis, Cleft Palate surgery, Ear Diseases diagnosis, Eustachian Tube
- Abstract
Objective: In patients with cleft palate, a high incidence of chronic obstructive Eustachian tube dysfunction (ETD) is assumed after surgery. Consequently, an increased rate of retracted eardrum or cholesteatoma is expected. Even though no common standard for investigating ETD is available, the development of objective tests has increased during the past 10 years. This study aimed to investigate the incidence of persisting chronic obstructive ETD in adult patients with cleft palate surgically treated in early childhood by using a combination of diagnostic tools., Methods: Adult participants with cleft palate repair in early childhood were invited for a follow-up examination and compared to a control group. Examination included tympanometry, tubomanometry, the Eustachian Tube Dysfunction Questionnaire (ETDQ-7), and the Eustachian Tube Score 7 (ETS-7)., Results: A total of 16 adult patients were re-examined after cleft palate surgery and compared to a control group of 40 healthy individuals. Significant differences were found in the median ETS‑7 (p < 0.0001) score but not in the median ETDQ‑7 (p = 0.09) score. Only 2 of the 32 investigated ears (6%) had pathologic scores in ETS‑7 and ETDQ‑7 (p = 0.09), whereas 5 (31%) cleft palate patients showed symptoms of chronic obstructive ETD according to ETS‑7. No patient had examination findings indicating a requirement for further treatment., Conclusion: By combining diagnostic tools for ETD, a lower rate of persisting obstructive ETD in adults after cleft palate surgery was found than previously reported. Successful surgical treatment of cleft palate seems to lead to physiological Eustachian tube function in long-term follow up., (© 2022. The Author(s).)
- Published
- 2022
- Full Text
- View/download PDF
132. Interactive live-stream surgery contributes to surgical education in the context of contact restrictions.
- Author
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van Bonn SM, Grajek JS, Schneider A, Oberhoffner T, Mlynski R, and Weiss NM
- Subjects
- Humans, Teaching, Learning, Students
- Abstract
Background: Attendance teaching is the predominant teaching method at universities but needs to be questioned in the context of digital transformation. This study establishes and evaluates a method to accomplish electronic learning to supplement traditional attendance courses., Materials and Methods: Surgery was transmitted in real-time conditions via an online live stream from the surgical theater. Visualization was transferred from a fully digital surgical microscope, an endoscope or an environmental camera in high definition quality. Students were able to participate at home from their personal computer. After following the surgery, they participated in an online-evaluation., Results: A total of 65 students participated in the live stream. The majority of students (61.54%) indicated a significant subjective increase in knowledge after participation. The majority of students (53.85%) indicated that live surgeries should be offered as a permanent component in addition to classroom teaching. Likewise, a broader offer was desired by many students (63.08%)., Conclusions: Live streaming of surgery is a promising approach as an alternative or supplement to traditional attendance teaching. An expansion of digital teaching can be explicitly supported on the basis of this study., (© 2021. The Author(s).)
- Published
- 2022
- Full Text
- View/download PDF
133. External auditory exostoses in wind-dependent water sports participants: German wind- and kitesurfers.
- Author
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Wegener F, Wegner M, and Weiss NM
- Subjects
- Cross-Sectional Studies, Ear Canal surgery, Humans, Retrospective Studies, Water, Wind, Exostoses epidemiology, Exostoses etiology, Water Sports
- Abstract
Purpose: Cold water and wind are known to cause exostoses of the external auditory canal. Different prevalences in different sports have been described in the literature. The aim of this study was to investigate the prevalence of external auditory exostosis (EAE) and EAE severity in coastal German wind- and kitesurfers who are exposed to cold water and strong winds. Furthermore, influencing factors such as the total exposure time and frequency of activity as well as the correlations between symptoms and the severity of EAE were investigated., Methods: In this retrospective cross-sectional study, German non-professional wind- and kitesurfers along the North and Baltic Sea coasts were recruited between September 2020 and November 2020. Each participant was interviewed about exposure time and otological symptoms and underwent bilateral video otoscopic examination to determine EAE severity., Results: A total of 241 ears from 130 subjects were analysed. The prevalence of EAE was 75.1%. In 19.9% of the participants, severe EAE was found. Exposure time and the frequency of activity had significant effects on the severity of EAE. Compared to surfers, EAE growth seems to progress faster in wind- and kitesurfers. The number of symptoms requiring medical treatment increased when two-thirds of the external auditory canal was obstructed., Conclusion: The prevalence of EAE in wind- and kitesurfers is high. Total exposure time and the frequency of activity influence EAE growth. EAE growth occurs faster in wind- and kitesurfers than in surfers. The additional influence of wind and the evaporative cooling of the EAC are thought to be responsible. The results of this study should increase awareness of the dynamics of EAE among ENT specialists and improve patient counselling., (© 2021. The Author(s).)
- Published
- 2022
- Full Text
- View/download PDF
134. CT imaging-based approaches to cochlear duct length estimation-a human temporal bone study.
- Author
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Breitsprecher T, Dhanasingh A, Schulze M, Kipp M, Dakah RA, Oberhoffner T, Dau M, Frerich B, Weber MA, Langner S, Mlynski R, and Weiss NM
- Subjects
- Cochlea diagnostic imaging, Cochlear Duct surgery, Cone-Beam Computed Tomography, Electrodes, Implanted, Humans, Reproducibility of Results, Temporal Bone diagnostic imaging, Tomography, X-Ray Computed, Cochlear Implantation, Cochlear Implants
- Abstract
Objectives: Knowledge about cochlear duct length (CDL) may assist electrode choice in cochlear implantation (CI). However, no gold standard for clinical applicable estimation of CDL exists. The aim of this study is (1) to determine the most reliable radiological imaging method and imaging processing software for measuring CDL from clinical routine imaging and (2) to accurately predict the insertion depth of the CI electrode., Methods: Twenty human temporal bones were examined using different sectional imaging techniques (high-resolution computed tomography [HRCT] and cone beam computed tomography [CBCT]). CDL was measured using three methods: length estimation using (1) a dedicated preclinical 3D reconstruction software, (2) the established A-value method, and (3) a clinically approved otosurgical planning software. Temporal bones were implanted with a 31.5-mm CI electrode and measurements were compared to a reference based on the CI electrode insertion angle measured by radiographs in Stenvers projection (CDL
reference )., Results: A mean cochlear coverage of 74% (SD 7.4%) was found. The CDLreference showed significant differences to each other method (p < 0.001). The strongest correlation to the CDLreference was found for the otosurgical planning software-based method obtained from HRCT (CDLSW-HRCT ; r = 0.87, p < 0.001) and from CBCT (CDLSW-CBCT ; r = 0.76, p < 0.001). Overall, CDL was underestimated by each applied method. The inter-rater reliability was fair for the CDL estimation based on 3D reconstruction from CBCT (CDL3D-CBCT ; intra-class correlation coefficient [ICC] = 0.43), good for CDL estimation based on 3D reconstruction from HRCT (CDL3D-HRCT ; ICC = 0.71), poor for CDL estimation based on the A-value method from HRCT (CDLA-HRCT ; ICC = 0.29), and excellent for CDL estimation based on the A-value method from CBCT (CDLA-CBCT ; ICC = 0.87) as well as for the CDLSW-HRCT (ICC = 0.94), CDLSW-CBCT (ICC = 0.94) and CDLreference (ICC = 0.87)., Conclusions: All approaches would have led to an electrode choice of rather too short electrodes. Concerning treatment decisions based on CDL measurements, the otosurgical planning software-based method has to be recommended. The best inter-rater reliability was found for CDLA-CBCT , for CDLSW-HRCT , for CDLSW-CBCT , and for CDLreference ., Key Points: • Clinically applicable calculations using high-resolution CT and cone beam CT underestimate the cochlear size. • Ten percent of cochlear duct length need to be added to current calculations in order to predict the postoperative CI electrode position. • The clinically approved otosurgical planning software-based method software is the most suitable to estimate the cochlear duct length and shows an excellent inter-rater reliability., (© 2021. The Author(s).)- Published
- 2022
- Full Text
- View/download PDF
135. [Mastoid cavity obliteration with allogenic and autologous material].
- Author
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Weiss N, Stallbaum T, Botzen J, Bächinger D, Großmann W, Bernd HE, and Mlynski R
- Subjects
- Humans, Mastoid surgery, Middle Aged, Prospective Studies, Quality of Life, Retrospective Studies, Treatment Outcome, Cholesteatoma, Middle Ear surgery, Hematopoietic Stem Cell Transplantation
- Abstract
Introduction: Surgical obliteration is the treatment of choice for symptomatic mastoid cavities. Various methods and materials are available. Allogeneic material is easily available but can lead to wound infections due to rejection, granulation and inflammatory reactions. Consequently, autologous material is often preferred due to its good biocompatibility. The aim of this study was to compare the long-term outcomes of patients after mastoid cavity obliteration with allogeneic and autologous material with regard to the occurrence of recurrent cholesteatoma, the number of revision surgeries and the impact of surgery on the health-related quality of life., Methods: Patients who underwent mastoid cavity obliteration with an allogeneic material (hydroxyapatite matrix [HMM]) were retrospectively included in the study. In a prospective part, patients who underwent mastoid cavity obliteration with autologous reconstruction material (AutoM) were included. In addition to a detailed chart review, all patients underwent pure tone audiometry and completed the Zurich Chronic Middle Ear Inventory (ZCMEI-21) at the postoperative examination to assess health-related disease-specific quality of life., Results: A total of 22 patients with a mean age of 56.9 (SD 18.7 years) receiving HMM (mean follow-up interval: 88.3 months [SD 21.9 months]) and 25 patients with a mean age of 52.4 years (SD 13.7 years) receiving AutoM (mean follow-up interval: 13.5 months [SD 9.5 months]) were included in the study. The revision-free rate for audiological indication after one year was 100% for HMM and 85% for AutoM. The recurrence-free rate at one year was 95% for HMM and 100% for AutoM. 55% of the patients with alloplastic material and 8% of the patients with autologous material required revision surgery due to ear discharge or recurrent cholesteatoma. The groups did not differ in terms of postoperative hearing outcome or postoperative quality of life., Discussion: Obliteration of mastoid cavities is a surgical challenge. There was no relevant difference between the materials used in terms of recurrence rate, hearing and health-related quality of life within the 13.5-month observation period of both groups. The lack of subjective symptoms together with the high rate of recurrent cholesteatoma and revision indications emphasises the need for regular clinical follow-up including ear microscopy in chronic middle ear disease and strongly suggests regular follow-up examinations., Competing Interests: Die Autoren geben an, keine Interessenkonflikte zu haben. Vorresultate der Studie wurden bereits auf Englisch publiziert (Weiss et al., Otol Neurotol 41:e55 – e63, 2020)., (Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany.)
- Published
- 2022
- Full Text
- View/download PDF
136. [Correction: Mastoid cavity obliteration with allogenic and autologous material].
- Author
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Weiss N, Stallbaum T, Botzen J, Bächinger D, Großmann W, Bernd HE, and Mlynski R
- Abstract
Competing Interests: Die Autoren geben an, keine Interessenkonflikte zu haben. Vorresultate der Studie wurden bereits auf Englisch publiziert (Weiss et al., Otol Neurotol 41:e55 – e63, 2020).
- Published
- 2021
- Full Text
- View/download PDF
137. Rare Diseases of the Middle Ear and Lateral Skull Base.
- Author
-
Weiss NM
- Subjects
- Ear, Middle, Earache, Humans, Skull Base surgery, Hearing Loss, Rare Diseases diagnosis, Rare Diseases therapy
- Abstract
Otalgia, otorrhea and hearing loss are the most common ear-related symptoms that lead to the consultation of an otolaryngologist. Furthermore, balance disorders and affections of the cranial nerve function may play a role in the consultation. In large academic centres, but also in primary care, the identification of rare diseases of the middle ear and the lateral skull base is essential, as these diseases often require interdisciplinary approaches to establish the correct diagnosis and to initiate safe and adequate treatments. This review provides an overview of rare bone, neoplastic, haematological, autoimmunological and infectious disorders as well as malformations that may manifest in the middle ear and the lateral skull base. Knowledge of rare disorders is an essential factor ensuring the quality of patient care, in particular surgical procedures. Notably, in untypical, complicated, and prolonged disease courses, rare differential diagnoses need to be considered., Competing Interests: Die Autorin gibt an, dass kein Interessenkonflikt besteht., (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).)
- Published
- 2021
- Full Text
- View/download PDF
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