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13,149 results on '"Yan Mei"'

101. Erratum to: CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling

Author

Dong-Fang Meng, Ping Xie, Li-Xia Peng, Rui Sun, Dong-Hua Luo, Qiu-Yan Chen, Xing Lv, Lin Wang, Ming-Yuan Chen, Hai-Qiang Mai, Ling Guo, Xiang Guo, Li-Sheng Zheng, Li Cao, Jun-Ping Yang, Meng-Yao Wang, Yan Mei, Yuan-Yuan Qiang, Zi-Meng Zhang, Jing-Ping Yun, Bi-Jun Huang, and Chao-Nan Qian

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published
2017
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102. Identification of gene expression changes from colitis to CRC in the mouse CAC model.

Author

Xin Li, Yuyan Gao, Ming Yang, Qi Zhao, Guangyu Wang, Yan Mei Yang, Yue Yang, Hui Liu, and Yanqiao Zhang

Subjects
Medicine, Science
Abstract

A connection between colorectal carcinogenesis and inflammation is well known, but the underlying molecular mechanisms have not been elucidated. Chemically induced colitis-associated cancer (CAC) is an outstanding mouse model for studying the link between inflammation and cancer. Additionally, the CAC model is used for examining novel diagnostic, prognostic, and predictive markers for use in clinical practice. Here, a CAC model was established in less than 100 days using azoxymethane (AOM) with dextran sulfate sodium salt (DSS) in BALB/c mice. We examined the mRNA expression profiles of three groups: control untreated mice (K), DSS-induced chronic colitis mice (D), and AOM/DSS-induced CAC (AD) mice. We identified 6301 differentially expressed genes (DEGs) among the three groups, including 93 persistently upregulated genes and 139 persistently downregulated genes. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed that the most persistent DEGs were significantly enriched in metabolic or inflammatory components in the tumor microenvironment. Furthermore, several associated DEGs were identified as potential DEGs by protein-protein interaction (PPI) network analysis. We selected 14 key genes from the DEGs and potential DEGs for further quantitative real-time PCR (qPCR) verification. Six persistently upregulated, 3 persistently downregulated DEGs, and the other 3 genes showed results consistent with the microarray data. We demonstrated the regulation of 12 key genes specifically involved in Wnt signaling, cytokine and cytokine receptor interactions, homeostasis, and tumor-associated metabolism during colitis-associated CRC. Our results suggest that a close relationship between metabolic and inflammatory mediators of the tumor microenvironment is present in CAC.

Published
2014
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145. Bis[N,N-bis(2-hydroxyethyl)dithiocarbamato-κ2S,S′]copper(II)

Author

Jun Fan, Yan Mei, Yun Zhong, and Lan-Feng Hou

Subjects
Crystallography, QD901-999
Abstract

In the title compound, [Cu(C5H10NO2S2)2], the CuII cation is chelated by two bis(2-hydroxyethyl)dithiocarbamate anions with a distorted square-planar coordination geometry. Intermolecular O—H...O hydrogen bonding is observed between the terminal hydroxy groups in the crystal structure.

Published
2009
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146. Highly charged Nd$^{9+}$ Ion: A potential candidate of $\upmu$Hz linewidth optical clocks for probing fundamental physics

Author

Yu, Yan-mei, Pan, Duo, Chen, Shaolong, Guan, Hua, Gao, Kelin, and Chen, Jingbiao

Subjects
Physics - Atomic Physics
Abstract

An active optical clock based on highly charged Nd$^{9+}$ ion is proposed for the first time. The clock can offer ultra-narrow linewidth at the $\upmu$Hz-level which is more than two-order of magnitude below the currently recorded laser linewidth. Operating at 605(90) nm superradiation lasing transition between the $5p^2~4f$ ground state and one of the long-lived $5p~4f^2$ excited state, the proposed active clock is inherently immune against the cavity noise which provides high stability. The clock serves as a sensitive probe with high sensitivity to variation of the fine-structure constant with accuracies below 10$^{-19}$ level. Sophisticated relativistic many-body methods are employed to predict related atomic properties that have corroborated the above findings., Comment: 5 papges, 2 figures, 1 SM

Published
2021

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