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Objective: To describe the attitude of elementary and middle school students and their parents toward children affected by HIV/AIDS and to analyze the determinants of such attitude., Methods: A cross-sectional study with the stratified cluster sampling method was conducted to interview elementary and middle school students and their parents, and questionnaires were distributed to collect information about the basic characteristics, HIV/AIDS knowledge and attitude toward children affected by HIV/AIDS. Student's t-test, ANOVA and multilevel model were used to analyze the data., Results: A total of 732 students and their parents finished the questionnaires. The students' and parents' awareness rates were 77.56% (95% CI: 63.08% - 92.05%)and 81.76% (95% CI: 72.33% - 91.20%), respectively. Questions with the lowest proportion of positive attitude included separating the children affected by HIV/AIDS and not studying with those children in the same class. Gender (b =-1.15, P =0.016) and knowledge (b =1.26, P <0.001) of students, as well as attitude (b =0.40, P <0.001) of parents were associated with the students' attitude, while parents' knowledge (b =0.93, P <0.001) was associated with parents' attitude., Conclusion: Discrimination towards children affected by HIV/AIDS exists among students and their parents. HIV/AIDS knowledge education helps to improve the students' and parents' caring and supporting attitude toward children affected by HIV/AIDS.

Objective: To investigate the infection of hemorrhagic fever with renal syndrome (HFRS) in host animals and inapparent infection of HFRS in general population in Dongting Lake areas after floods., Methods: The night trapping method was used to capture rodents. The immunofluorescence assays were used to detect the hantavirus (HV) antigens and antibodies in rodents lung and in the serum of general population. Nonconditional logistic regression was applied to analyze risk factors for inapparent infection with HV., Results: In flood region,draw-near flood region and new migration region,rodent density was 6.95%,6.28%, and 8.67%, respectively, and the virus-carrying rate in rodents was 15.07%,9.25%, and 4.47%, respectively. The virus-carrying rat index was the highest in flood region (0.10). Apodemus agrarius was the dominant species. The standardized positive rate of HV antibody in general population from above mentioned regions was 4.49%, 3.11%, and 3.13%, respectively. There was no significant difference among different age or gender groups. The results of logistic regression analysis indicated that people who were involved in construction of water conservancy facilities in winter or practice of rat extermination at home were the principal factors related to inapparent infection with HV., Conclusion: The virus-carrying rate in main host animals of HV in the 3 regions is high, whereas the positive rate of HV antibody is low in general population. Comprehensive measures should be taken to prevent and control HFRS, such as reinforcing surveillance of HFRS, strengthening deratization, and preventive inoculation.

Objective: To analyze the reliability and validity of a sub-health symptom check scale for college students., Methods: Using a multi-phase cluster sampling method, a total of 1200 college students from Changsha city were tested with a sub-health symptom check scale; 1143 valid questionnaires were received to assess the internal consistency reliability coefficient and split-half reliability coefficient; 111 students were retested 14 days later to assess the reliability of the scale, 112 students were also tested with the Symptom Checklist 90 (SCL-90) to evaluate the criterion-related validity of the scale., Results: The Cronbach's alpha coefficient of the questionnaire was 0.946 and the test-retest correlation coefficient was 0.701. Taking SCL-90 as a criterion, the criterion-related validity of the scale was 0.875. The scores of the scale were significantly different in gender and between sub-healthy and healthy students., Conclusion: The scale is reliable, effective, and sensitive, and could be applied to evaluate the sub-health status of college students.

Objective: To explore the relationship between posttraumatic stress disorder (PTSD) in flood victim parents and children in Hunan, China., Methods: Using the method of multistage cluster random sampling, we conducted a retrospective investigation on 3,698 families in Hunan, China who suffered from flooding in 1998. Investigators held face-to-face interviews with the parents and children of the families. The diagnosis of PTSD was made according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition. The comparison of rate of PTSD positive in the groups of children with different characteristics was done by chi-square test. In the evaluation of the impact of parent PTSD on PTSD in their children, we used a multivariable logistic regression model to re-estimate the adjusted Odds Ratio and its confidence interval. We did this after the possible confounding variables were adjusted for. Additionally, the Odds Ratio and its confidence interval were estimated under the condition of a single variable., Results: A total of 4,327 children and the parents of 3,292 families were included for analysis; 203 (4.7%) of 4,327 children and 740 (11.2%) of 6,584 parents were diagnosed with PTSD. We found that the PTSD positive rate is significantly higher in the children with disaster-related experience. The rate of beating their children in PTSD positive fathers (54.9%) was higher than that of PTSD negative fathers (51.2%). No correlation was found between mothers' PTSD and beating their children. The risk of developing PTSD is higher for children living in the families with PTSD parents., Conclusion: The rate of PTSD in 7-14-year-old children is 4.7% in areas in Hunan, China, who suffered from flooding in 1998. The possibility for children to develop PTSD is increased in families with PTSD parents.

Objective: To estimate the benefit and cost of increasing the coverage of cervical cancer screening., Methods: Using an eleven year conventional screening data (universal strategy) and a representative population sample (expanding strategy) to analyze the health and economic impact., Results: The screening coverage for all 30-59 women in Liuyang was increased from 7.20% to 66.67%. Early detection cases were increased from 20 to 45, and life years saved in one screening term increased from 103.46 years to 925.83 years with expanding strategy as compared with the conventional strategy. The incremental cost per life year saved was 6 917.07 Yuan. The benefit/cost ratio was 1.80:1 at the screening coverage of 66.67%, which was higher than that of the conventional strategy (1.40:1). Both strategies were cost-effective., Conclusion: With various uncertainties and data limitations, expanding screening coverage is more effective than conventional strategy, and more benefit is obtained when the number of early detection cases increases.

Objective: To investigate the infection of leptospirosa of host animals and the immune level of healthy population in flood areas., Methods: Korth culture was used to culture leptospira for rodent kidney and oxen urine sample. The serogroups of leptospira and leptospira antibody were tested by microscopic agglutination test (MAT)., Results: In flood regions, draw-near-flood region, and new migration region, rodent density was 6.95%, 6.28%, and 8.67%, respectively. The positive rates of rodent with leptospira was 4.63%, 1.35%, and 3.13%, respectively. Leptospira positive rates of oxen urine were 5.88%, 5.98%, and 1.75%, respectively. The main serogroup of leptospira was Icterhamorrhagic and Canicola serogroup. The positive rates of leptospirosa antibody in healthy population was 45.91%, 62.30%, and 58.67%in these 3 regions respectively, which was significantly higher than the average level in China. The dominant serogroups of leptospira in health population were icterhamorrhagic, autumnalis, canicola, pomona and bataviae. The positive rate of antibody had no difference among different age groups., Conclusion: The main host animals are rodents and oxen infected with leptospira and the positive rate of leptospira antibody is high in healthy population in the study area. The dominant serogroups in host animals are similar to that in healthy population, which is mostly icterhaemorrhagic.