142 results on '"Zeng, Yawen"'
Search Results
102. HHA: An Attentive Prediction Model for Academic Abnormality
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Zeng, Yawen, primary, Ouyang, Yong, additional, Gao, Rong, additional, Qiu, Ye, additional, Yu, Yonghong, additional, and Wang, Chunzhi, additional
- Published
- 2020
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103. Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review
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Zhang, Zhiqin, primary, Bai, Jie, additional, Zeng, Yawen, additional, Cai, Mengru, additional, Yao, Yu, additional, Wu, Huimin, additional, You, Longtai, additional, Dong, Xiaoxv, additional, and Ni, Jian, additional
- Published
- 2020
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104. Aloe‐emodin: A review of its pharmacology, toxicity, and pharmacokinetics
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Dong, Xiaoxv, primary, Zeng, Yawen, additional, Liu, Yi, additional, You, Longtai, additional, Yin, Xingbin, additional, Fu, Jing, additional, and Ni, Jian, additional
- Published
- 2019
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105. Preventive and Therapeutic Role of Functional Ingredients of Barley Grass for Chronic Diseases in Human Beings
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Zeng, Yawen, Pu, Xiaoying, Yang, Jiazhen, Du, Juan, Yang, Xiaomeng, Li, Xia, Li, Ling, Zhou, Yan, and Yang, Tao
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Article Subject ,food and beverages - Abstract
Barley grass powder is the best functional food that provides nutrition and eliminates toxins from cells in human beings; however, its functional ingredients have played an important role as health benefit. In order to better cognize the preventive and therapeutic role of barley grass for chronic diseases, we carried out the systematic strategies for functional ingredients of barley grass, based on the comprehensive databases, especially the PubMed, Baidu, ISI Web of Science, and CNKI, between 2008 and 2017. Barley grass is rich in functional ingredients, such as gamma-aminobutyric acid (GABA), flavonoids, saponarin, lutonarin, superoxide dismutase (SOD), K, Ca, Se, tryptophan, chlorophyll, vitamins (A, B1, C, and E), dietary fiber, polysaccharide, alkaloid, metallothioneins, and polyphenols. Barley grass promotes sleep; has antidiabetic effect; regulates blood pressure; enhances immunity; protects liver; has anti-acne/detoxifying and antidepressant effects; improves gastrointestinal function; has anticancer, anti-inflammatory, antioxidant, hypolipidemic, and antigout effects; reduces hyperuricemia; prevents hypoxia, cardiovascular diseases, fatigue, and constipation; alleviates atopic dermatitis; is a calcium supplement; improves cognition; and so on. These results support that barley grass may be one of the best functional foods for preventive chronic diseases and the best raw material of modern diet structure in promoting the development of large health industry and further reveal that GABA, flavonoids, SOD, K-Ca, vitamins, and tryptophan mechanism of barley grass have preventive and therapeutic role for chronic diseases. This paper can be used as a scientific evidence for developing functional foods and novel drugs for barley grass for preventive chronic diseases.
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- 2018
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106. Genetic analysis of four main flavonoids in barley grain
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Yang, Tao, primary, Zeng, Yawen, primary, Du, Juan, primary, Yang, Shuming, primary, and Pu, Xiaoying, primary
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- 2019
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107. Near-Isogenic Lines of Japonica Rice Revealed New QTLs for Cold Tolerance at Booting Stage
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Sun, Zhenghai, primary, Du, Juan, additional, Pu, Xiaoying, additional, Kazim Ali, Muhammad, additional, Yang, Xiaomeng, additional, Duan, Chengli, additional, Ren, Meirong, additional, Li, Xia, additional, and Zeng, Yawen, additional
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- 2019
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108. Traction of Students' Curriculum Information Based on Association Rule Optimization
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Zhou, Zhe, primary, Ouyang, Yong, primary, and Zeng, Yawen, primary
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- 2019
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109. Chemical Constituents of Functional Food Amomum villosum to CombatHuman Diseases
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Zeng, Yawen, Ali, Muhammad Kazim, He, Wei, Deng, Lin, Yang, Xiaomeng, Li, Xia, Pu, Xiaoying, and Yang, Jiazhen
- Abstract
Background: Amomum villosum is an important medicinal and edible plant owing to itsvaluable compositions of volatile and non-volatile compounds. Objective: The study was conducted to reveal the chemical constituents and medicinal values of A. villosumagainst various diseases. Methods: A critical and comprehensive data mining from 2004 to 2021 was performed based onCNKI, PubMed, and Google. Results: 120 Compounds have been reported collectively in seeds, peels, and rhizomes of A. villosum,10 compounds were common however the content of bornyl acetate was maximum inseeds and peels. Similarly, Amomi fructus of China and Vietnam showed 59 different types ofvolatile compounds while 13 were common, the round large black fruits (1.56% bornyl acetateand 4.05% volatile oil) and long small red fruits type (1.64% bornyl acetate and 3.04% volatileoil) from China showed good quality and high medicinal values. In addition, Amomi fructus manifested30-40 kinds of nonvolatile compounds, i.e., phenolic, polysaccharides, saponins, flavonoid,vanillic acid, catechin, epicatechin, polydatin, isoquercitrin, quercitrin, glycosides, inorganic andorganic acids. Conclusion: A. villosum is widely used as anti-inflammatory, gastrointestinal protection, antiobesity,anticancer, antioxidant, analgesic, bacteriostasis, antidiabetic and anti-COVID-19, etc. So,it is manifested that the fruit, flowers, roots, stems, and leaves of A. villosum can be used as amedicine, especially fruit (Amomi fructus=Sharen), as the best functional food for the COVID-19treatment and gastrointestinal protection as well as prevention of other diseases.
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- 2022
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110. Therapeutic Role of Functional Components in Alliums for Preventive Chronic Disease in Human Being
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Zeng, Yawen, Li, Yuping, Yang, Jiazhen, Pu, Xiaoying, Du, Juan, Yang, Xiaomeng, Yang, Tao, and Yang, Shuming
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Article Subject ,food and beverages - Abstract
Objectives. Functional components in alliums have long been maintained to play a key role in modifying the major risk factors for chronic disease. To obtain a better understanding of alliums for chronic disease prevention, we conducted a systematic review for risk factors and prevention strategies for chronic disease of functional components in alliums, based on a comprehensive English literature search that was conducted using various electronic search databases, especially the PubMed, ISI Web of Science, and CNKI for the period 2007–2016. Allium genus especially garlic, onion, and Chinese chive is rich in organosulfur compounds, quercetin, flavonoids, saponins, and others, which have anticancer, preventive cardiovascular and heart diseases, anti-inflammation, antiobesity, antidiabetes, antioxidants, antimicrobial activity, neuroprotective and immunological effects, and so on. These results support Allium genus; garlic and onion especially may be the promising dietotherapeutic vegetables and organopolysulfides as well as quercetin mechanism in the treatment of chronic diseases. This review may be used as scientific basis for the development of functional food, nutraceuticals, and alternative drugs to improve the chronic diseases.
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- 2017
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111. A modeling method for photovoltaic cells using explicit equations and optimization algorithm
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Shun Tao, Xiangning Xiao, Zeng Yawen, Kong Xiangyu, and Xu Yonghai
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Current (mathematics) ,Implicit function ,Optimization algorithm ,Numerical analysis ,Photovoltaic system ,Mathematical analysis ,Energy Engineering and Power Technology ,symbols.namesake ,Lambert W function ,symbols ,Applied mathematics ,Electrical and Electronic Engineering ,Mathematics ,Voltage - Abstract
A numerical method for determining the five-parameter model of photovoltaic cells is presented in the paper. Explicit equations are applied to analyze the relations between parameters which are solved by an optimization algorithm. Lambert W function is implemented to convert the I–V characteristic implicit equation to an explicit one, so the output current and voltage of photovoltaic cells can be obtained by substituting the five parameters into the explicit I–V equation. Several cells are used to verify the accuracy of the proposed method from different aspects. It is found that the proposed method gives precise results and can be applicable to various types of photovoltaic cells.
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- 2014
112. Aloe-emodin: A review of its pharmacology, toxicity, and pharmacokinetics.
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Dong, Xiaoxv, Zeng, Yawen, Liu, Yi, You, Longtai, Yin, Xingbin, Fu, Jing, and Ni, Jian
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QUINONE ,PLANTS ,RHUBARB ,ALOE ,RESEARCH funding ,ANIMALS - Abstract
Aloe-emodin is a naturally anthraquinone derivative and an active ingredient of Chinese herbs, such as Cassia occidentalis, Rheum palmatum L., Aloe vera, and Polygonum multiflorum Thunb. Emerging evidence suggests that aloe-emodin exhibits many pharmacological effects, including anticancer, antivirus, anti-inflammatory, antibacterial, antiparasitic, neuroprotective, and hepatoprotective activities. These pharmacological properties lay the foundation for the treatment of various diseases, including influenza virus, inflammation, sepsis, Alzheimer's disease, glaucoma, malaria, liver fibrosis, psoriasis, Type 2 diabetes, growth disorders, and several types of cancers. However, an increasing number of published studies have reported adverse effects of aloe-emodin. The primary toxicity among these reports is hepatotoxicity and nephrotoxicity, which are of wide concern worldwide. Pharmacokinetic studies have demonstrated that aloe-emodin has a poor intestinal absorption, short elimination half-life, and low bioavailability. This review aims to provide a comprehensive summary of the pharmacology, toxicity, and pharmacokinetics of aloe-emodin reported to date with an emphasis on its biological properties and mechanisms of action. [ABSTRACT FROM AUTHOR]
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- 2020
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113. Molecular Mechanism and Health Role of Functional Ingredients in Blueberry for Chronic Disease in Human Beings
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Ma, Luyao, primary, Sun, Zhenghai, additional, Zeng, Yawen, additional, Luo, Mingcan, additional, and Yang, Jiazhen, additional
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- 2018
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114. A-Stock Price Fluctuation Forecast Model Based on LSTM
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Zeng, Yawen, primary and Liu, Xing, additional
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- 2018
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115. Effects of resistant starch content on mixture and cooking among different genotypes rice
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Xie YongWu, Wang JinJin, Pu XiaoYing, Du Juan, Yang ShuMing, Yang Tao, and Zeng YaWen
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chemistry.chemical_compound ,Horticulture ,food.ingredient ,food ,chemistry ,Agronomy ,Starch ,food and beverages ,Brown rice ,Cultivar ,Resistant starch ,Biology ,Japonica rice - Abstract
Through orthogonal experiment designs L4(23),the content changes of resistant starch on mixture and cooking among three different kinds of genotypes rice,indica rice,japonica rice and glutinous rice were studied with cultivar Gongmi3 in high resistant starch content as the material.It provids a theoretical and practical basis for producting main food of diabetes.The results showed:1) The contents of resistant starch of different genotypes rice were significantly different,which was effected by processing and cooking condition.It was higher than polished ricein brown rice and the contents of resistant starch of cooked rice were higher than those of raw rice.2) The effects of resistant starch content of the all factors were also obvious among the mixture ratio of different genotypes rice as well as the ratio of water between the rice of cook and the cook times.The influence of resistant starch was significantly varied from genotypes to process.There existed highly significant differences in producing the resistant starch with cooking optimum parameters.The contents of resistant starch in polished rice were higher than that in brown rice while the contents of resistant starch of indica and japonica rice were higher than that in glutinous rice.
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- 2011
116. Identification of QTLs controlling grain protein concentration using a high-density SNP and SSR linkage map in barley (Hordeum vulgare L.)
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Fan, Chaofeng, primary, Zhai, Huijie, additional, Wang, Huifang, additional, Yue, Yafei, additional, Zhang, Minghu, additional, Li, Jinghui, additional, Wen, Shaozhe, additional, Guo, Ganggang, additional, Zeng, Yawen, additional, Ni, Zhongfu, additional, and You, Mingshan, additional
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- 2017
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117. Natural variation in CTB4a enhances rice adaptation to cold habitats
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Zhang, Zhanying, primary, Li, Jinjie, additional, Pan, Yinghua, additional, Li, Jilong, additional, zhou, Lei, additional, Shi, Hongli, additional, Zeng, Yawen, additional, Guo, Haifeng, additional, Yang, Shuming, additional, Zheng, Weiwei, additional, Yu, Jianping, additional, Sun, Xingming, additional, Li, Gangling, additional, Ding, Yanglin, additional, Ma, Liang, additional, Shen, Shiquan, additional, Dai, Luyuan, additional, Zhang, Hongliang, additional, Yang, Shuhua, additional, Guo, Yan, additional, and Li, Zichao, additional
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- 2017
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118. High Performance Liquid Chromatography Fingerprinting of Flavonoids Between Parents and Generations in Barley Grain
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Yang, Tao, primary, Duan, Chengli, additional, Zeng, Yawen, additional, Du, Juan, additional, Yang, Shuming, additional, Pu, Xiaoying, additional, and Yang, Shengchao, additional
- Published
- 2017
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119. Coevolution between Cancer Activities and Food Structure of Human Being from Southwest China
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Zeng, Yawen, Du, Juan, Pu, Xiaoying, Yang, Jiazhen, Yang, Tao, Yang, Shuming, and Yang, Xiaomeng
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Article Subject ,fungi ,food and beverages ,psychological phenomena and processes ,geographic locations - Abstract
Yunnan and Tibet are the lowest cancer mortality and the largest producer for anticancer crops (brown rice, barley, buckwheat, tea, walnut, mushrooms, and so forth). Shanghai and Jiangsu province in China have the highest mortality of cancers, which are associated with the sharp decline of barley.
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- 2015
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120. [Untitled]
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Li ZiChao, Shen ShiQuan, Wen Guo-song, Yang Zhongyi, Wang XiangKun, Zhang HongLiang, and Zeng YaWen
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Germplasm ,Genetic diversity ,Oryza sativa ,Plant Science ,Biology ,biology.organism_classification ,Japonica ,Diversity index ,Agronomy ,Botany ,Genetics ,Cultivar ,Ecosystem diversity ,China ,Agronomy and Crop Science ,Ecology, Evolution, Behavior and Systematics - Abstract
Yunnan is one of the largest centres of genetic ecological diversity and the richest area for elite germplasm of rice (O. sativa L.) resources in the world. Its indigenous rice average diversity index of six ecological groups are, in turn, javanica (1.2319) > aman (1.1738) > communis (1.1726) > nuda (1.1618) > aus (1.1371) > boro (0.9889), and there are great differences between indica (1.1454) and japonica (1.2081). The indigenous rice in Yunnan can be divided into 58 varieties, almost the total number found in China, and the cultivars account for 8.6% of the total cultivars in China. A great difference in ecological diversity index of rice resources between prefectures or counties in Yunnan province also exists, with the southwest part (Lincang, Xishuangbanna, Dehong, Simao) and southeast part (Wenshan) having been found to be the largest centre of genetic diversity, as their average genetic diversity index ranges from 1.2735 to 1.2036, especially. The average diversity index of the Cangyuan, Gengma, Zhenkang, Yongde, Yingjiang, Jinghong, Menghai, Shuangjiang, Ruili, Longchuan, Mojiang, Wenshan and Guangnan counties, in particular, have an average diversity index ranging from 0.8 to1.0. On the contrary, in Diqing, Dongchuan, Kunming, Lijiang, Qujing, Chuxiong, it is comparatively low, i.e., 0.7843–1.1075. Differences in the ecological diversity index of rice resources between rice regions are small, only 1.1322 to 1.2849.
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- 2003
121. [Untitled]
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Wang Jianjun, Shen ShiQuan, Meng Jingui, Chen Xiaoyan, Wu Lihua, Yang Zongyi, and Zeng YaWen
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Sustainable development ,Genetic diversity ,Cultivated plant taxonomy ,Oryza sativa ,business.industry ,Agroforestry ,fungi ,Endangered species ,food and beverages ,Plant Science ,Subspecies ,Biology ,Crop ,Agronomy ,Agriculture ,Genetics ,business ,Agronomy and Crop Science ,Ecology, Evolution, Behavior and Systematics - Abstract
This paper reviews the status of crop genetic resources in Yunnan province of China from 1978 to 1999. Results are presented of same research in the field of the diversity of cultivated and wild crop. Yunnan is one of the centre of origin or genetic diversity of more than 200 cultivated and wild crops. There are over 500 cultivated plants which account for over 80% of the total in China and more than 650 species of wild crops. In addition, there are more than 440 species of main wild flowers. According to our recently researches there are abundant species, subspecies and varieties of crop genetic resources in Yunnan Province. The Lancang River Valley is the richest genetic diversity centre of rice, maize, wheat, barley, buckwheat, legumes, ramie, sugarcane, vegetable, tea, actinidia and so on. For example, there are 59 varieties (including all varieties of Oryza sativa L. in China) in 5933 accession of Yunnan indigenous rice. The Lancang River Valley is one of the centre for genetic diversity of rice resources and a rich region for elite and rare rice resources of Yunnan, too. In order to protect the highly endangered crop genetic resources in the Lancang River Valley, it is necessary and very important to set up a collection, conservation, utilization and research system, enhancing their protection and utilization, in situ- and ex situ-conservation, farm management and sustainable production.
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- 2001
122. Fine mapping of QTL qCTB10- 2 that confers cold tolerance at the booting stage in rice.
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Li, Jilong, Pan, Yinghua, Guo, Haifeng, Zhou, Lei, Yang, Shuming, Zhang, Zhanying, Yang, Jiazhen, Zhang, Hongliang, Li, Jinjie, Zeng, Yawen, and Li, Zichao
- Subjects
RICE genetics ,PLANT gene mapping ,EFFECT of cold on plants ,RICE varieties ,PLANT population genetics - Abstract
Key message: The QTL qCTB10 - 2 controlling cold tolerance at the booting stage in rice was delimited to a 132.5 kb region containing 17 candidate genes and 4 genes were cold-inducible. Abstract: Low temperature at the booting stage is a major abiotic stress-limiting rice production. Although some QTL for cold tolerance in rice have been reported, fine mapping of those QTL effective at the booting stage is few. Here, the near-isogenic line ZL31-2, selected from a BCF population derived from a cross between cold-tolerant variety Kunmingxiaobaigu (KMXBG) and the cold-sensitive variety Towada, was used to map a QTL on chromosome 10 for cold tolerance at the booting stage. Using BCF and BCF populations, we firstly confirmed qCTB10- 2 and gained confidence that it could be fine mapped. QTL qCTB10- 2 explained 13.9 and 15.9% of the phenotypic variances in those two generations, respectively. Using homozygous recombinants screened from larger BCF and BCF populations, qCTB10- 2 was delimited to a 132.5 kb region between markers RM25121 and MM0568. 17 putative predicted genes were located in the region and only 5 were predicted to encode expressed proteins. Expression patterns of these five genes demonstrated that, except for constant expression of LOC_Os10g11820, LOC_Os10g11730, LOC_Os10g11770, and LOC_Os10g11810 were highly induced by cold stress in ZL31-2 compared to Towada, while LOC_Os10g11750 showed little difference. Our results provide a basis for identifying the genes underlying qCTB10- 2 and indicate that markers linked to the qCTB10- 2 locus can be used to improve the cold tolerance of rice at the booting stage by marker-assisted selection. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
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123. Strategies of Functional Foods Promote Sleep in Human Being
- Author
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Zeng, Yawen, primary, Yang, Jiazhen, additional, Du, Juan, additional, Pu, Xiaoying, additional, Yang, Xiaomen, additional, Yang, Shuming, additional, and Yang, Tao, additional
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- 2015
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124. A generally synthetic route to semiconducting metal sulfide nanocrystals by using corresponding metal powder and cysteine as metallic and sulfuric sources, respectively
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Yu, Leshu, Lv, Yingying, Chen, Guangda, Zhang, Xiaolan, Zeng, Yawen, Huang, Heyong, and Feng, Yuying
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- 2011
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125. Use of functional foods for diabetes prevention in China
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Zeng, Yawen, primary
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- 2012
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126. Characterization and identification of cold tolerant near-isogenic lines in rice
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Zhou, Lei, primary, Zeng, Yawen, additional, Hu, Guanglong, additional, Pan, Yinghua, additional, Yang, Shuming, additional, You, Aiqing, additional, Zhang, Hongliang, additional, Li, Jinjie, additional, and Li, Zichao, additional
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- 2012
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127. Genotypic variation in element concentrations in brown rice from Yunnan landraces in China
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Zeng, Yawen, primary, Zhang, Hongliang, additional, Wang, Luxiang, additional, Pu, Xiaoying, additional, Du, Juan, additional, Yang, Shuming, additional, and Liu, Jiafu, additional
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- 2009
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128. Elemental Content in Brown Rice by Inductively Coupled Plasma Atomic Emission Spectroscopy Reveals the Evolution of Asian Cultivated Rice
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Zeng, Yawen, primary, Wang, Luxiang, additional, Du, Juan, additional, Liu, Jiafu, additional, Yang, Shuming, additional, Pu, Xiaoying, additional, and Xiao, Fenghui, additional
- Published
- 2009
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129. Evaluation of Genetic Diversity of Rice Landraces (Oryza sativa L.) in Yunnan, China
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Zeng, Yawen, primary, Zhang, Hongliang, additional, Li, Zichao, additional, Shen, Shiquan, additional, Sun, Jianli, additional, Wang, Meixing, additional, Liao, Dengqun, additional, Liu, Xia, additional, Wang, Xiangkun, additional, Xiao, Fenghui, additional, and Wen, Guosong, additional
- Published
- 2007
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130. Ecogeographic and genetic diversity based on morphological characters of indigenous rice (Oryza sativa L.) in Yunnan, China.
- Author
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Zeng Yawen, Shen Shiquan, Li Zichao, Yang Zhongyi, Wang Xiangkun, Zhang Hongliang, and Wen
- Abstract
Yunnan is one of the largest centres of genetic ecological diversity and the richest area for elite germplasm of rice (O. sativa L.) resources in the world. Its indigenous rice average diversity index of six ecological groups are, in turn, javanica (1.2319) > aman (1.1738) > communis (1.1726) > nuda (1.1618) > aus (1.1371) > boro (0.9889), and there are great differences between indica (1.1454) and japonica (1.2081). The indigenous rice in Yunnan can be divided into 58 varieties, almost the total number found in China, and the cultivars account for 8.6% of the total cultivars in China. A great difference in ecological diversity index of rice resources between prefectures or counties in Yunnan province also exists, with the southwest part (Lincang, Xishuangbanna, Dehong, Simao) and southeast part (Wenshan) having been found to be the largest centre of genetic diversity, as their average genetic diversity index ranges from 1.2735 to 1.2036, especially. The average diversity index of the Cangyuan, Gengma, Zhenkang, Yongde, Yingjiang, Jinghong, Menghai, Shuangjiang, Ruili, Longchuan, Mojiang, Wenshan and Guangnan counties, in particular, have an average diversity index ranging from 0.8 to1.0. On the contrary, in Diqing, Dongchuan, Kunming, Lijiang, Qujing, Chuxiong, it is comparatively low, i.e., 0.78431.1075. Differences in the ecological diversity index of rice resources between rice regions are small, only 1.1322 to 1.2849. [ABSTRACT FROM AUTHOR]
- Published
- 2003
131. Evolution and association analysis of SSIIIa in rice landraces of Yunnan Province.
- Author
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Li, Xia, Yang, Xiaomeng, Yang, Li'e, Muhu-Din Ahmed, Hafiz Ghulam, Yao, Chunlian, Yang, Jiazhen, Wang, Luxiang, Yang, Tao, Pu, Xiaoying, and Zeng, Yawen
- Subjects
- *
RICE , *GENETIC variation , *GERMPLASM , *RED rice , *HAPLOTYPES , *AMYLOSE - Abstract
The increasing incidence of diabetes and obesity poses a major threat to global human health worldwide. Increasing the consumption of resistant starch (RS) foods could reduce the occurrence of these chronic diseases.Accurate identification and screening of germplasm resources with high RS content is the initial step in breeding efforts, and Yunnan Province is recognized as the largest center of genetic diversity in Chinese rice varieties. However, there is a lack of systematic studies of genetic variation and evolution of RS content in rice landraces within this region. Here, we selected the SSIIIa gene as the subject that affected the content of RS in rice endosperm and analyzed its natural variation in 93 rice landraces in Yunnan province. Analyses of gene sequence information demonstrated that the 93 landraces were divided into 11 haplotypes and 10 protein types. Evolutionary analysis revealed that indica and japonica rice in these landraces appeared to have experienced different evolutionary. Among these haplotypes, the H4 haplotype exhibited the highest genetic similarity to the two Oryza rufipogon of Yunnan, and the content of RS was significantly higher than other haplotypes. Furthermore, association analysis identified 9 SNPs that consistently correlated with RS content, and revealed several new mutation sites. In addition, haplotypes with high RS content generally had higher amylose content and lower gel consistency. These results provided important experimental evidence for the utilization of high RS germplasm, and also lay the groundwork for further genetic research on the process of RS formation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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132. GC–MS based antioxidants characterization in Saussurea heteromalla (D. Don) Hand-Mazz by inhibition of nitric oxide generation in macrophages.
- Author
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Saboon, Iqbal, Asia, Bibi, Yamin, Afzal, Tayyiba, Sher, Ahmad, Qayyum, Abdul, Akmal, Muhammad, Almoallim, Hesham S., Ansari, Mohammad Javed, and Zeng, Yawen
- Abstract
For centuries, medicinal plants have served as the cornerstone for traditional health care systems and same practice is still prevalent today. In the Himalayan region, Saussurea heteromalla holds a significant place in traditional medicine and is used to address various health issues. Despite its historical use, little exploration has focused on its potential for scavenging free radicals and reducing inflammation. Hence, our current study aims to investigate the free radical scavenging capabilities of S. heteromalla extracts. The n-hexane extract of entire plant revealed promising activity. This extract underwent extensive extraction on a larger scale. Subsequent purification, employing column chromatography, HPLC–DAD techniques, led to the identification of active compounds, confirmed via GC–MS and the NIST database as 1-O-butyl 2-O-octyl benzene-1,2-dicarboxylate and 2,4-ditert-butylphenol. Assessing the free radical scavenging properties involved utilizing RAW-264.7 macrophages activated by lipopolysaccharides. Notably, the compound 2,4-di-tert-butylphenol exhibited remarkable scavenging abilities, demonstrating over 80% inhibition of Nitric oxide. This study stands as the inaugural report on the isolation of these compounds from S. heteromalla. [ABSTRACT FROM AUTHOR]
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- 2024
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133. Multi-level contrastive graph learning for academic abnormality prediction.
- Author
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Ouyang, Yong, Wang, Yuanlin, Gao, Rong, Zeng, Yawen, Liu, Jinhang, and Ye, Zhiwei
- Subjects
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PSYCHOLOGY of students , *INTERPOLATION spaces , *DATA augmentation , *HUMAN abnormalities , *LEARNING - Abstract
Academic Abnormality Prediction aims to predict whether students have academic abnormalities through their historical academic scores. However, existing research methods still have the following challenges: (1) Student behavior. Only the students' historical academic performance is considered, ignoring the impact of student behavior in student status. (2) Data imbalance. The number of academically abnormal students is much less than that of ordinary students, resulting in a data imbalance problem. Therefore, in response to the above challenges, this paper proposes a Multi-level Contrastive Graph learning for academic abnormality prediction (MCG). Specifically, firstly, we capture student behavior and fuse it with student historical achievement data based on a Graph Neural Network (GNN), Thereafter, we construct an embedding space for sample interpolation, which generates virtual nodes of abnormal students, thereby alleviating the data imbalance problem. Moreover, we introduce a multi-level contrastive learning module to precisely learn node representations and maximize the consistency between different views of the same node in the target and online networks for data augmentation. Experiments on real datasets show that the abnormality prediction performance of MCG outperforms the existing state-of-the-art methods. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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134. QTL detection and candidate gene identification of qCTB1 for cold tolerance in the Yunnan plateau landrace rice.
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Guo H, Guo Y, Zeng Y, Zou A, Khan NU, Gu Y, Li J, Sun X, Zhang Z, Zhang H, Peng Y, Li H, Wu Z, Yuan P, Li J, and Li Z
- Abstract
Cold stress is one of the main abiotic stresses that affects rice growth and production worldwide. Dissection of the genetic basis is important for genetic improvement of cold tolerance in rice. In this study, a new source of cold-tolerant accession from the Yunnan plateau, Lijiangxiaoheigu, was used as the donor parent and crossed with a cold-sensitive cultivar, Deyou17, to develop recombinant inbred lines (RILs) for quantitative trait locus (QTL) analysis for cold tolerance at the early seedling and booting stages in rice. In total, three QTLs for cold tolerance at the early seedling stage on chromosomes 2 and 7, and four QTLs at the booting stage on chromosomes 1, 3, 5, and 7, were identified. Haplotype and linear regression analyses showed that QTL pyramiding based on the additive effect of these favorable loci has good potential for cold tolerance breeding. Effect assessment in the RIL and BC
3 F3 populations demonstrated that qCTB1 had a stable effect on cold tolerance at the booting stage in the genetic segregation populations. Under different cold stress conditions, qCTB1 was fine-mapped to a 341-kb interval between markers M3 and M4. Through the combination of parental sequence comparison, candidate gene-based association analysis, and tissue and cold-induced expression analyses, eight important candidate genes for qCTB1 were identified. This study will provide genetic resources for molecular breeding and gene cloning to improve cold tolerance in rice., Supplementary Information: The online version contains supplementary material available at 10.1007/s11032-024-01488-3., Competing Interests: Conflict of interestsThe authors declare no conflicts of interest., (© The Author(s), under exclusive licence to Springer Nature B.V. 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)- Published
- 2024
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135. Physiological Mechanisms by Which the Functional Ingredients in Beer Impact Human Health.
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Zeng Y, Ahmed HGM, Li X, Yang L, Pu X, Yang X, Yang T, and Yang J
- Subjects
- Humans, Functional Food analysis, Polyphenols chemistry, Polyphenols analysis, Hordeum chemistry, Flavonoids chemistry, Flavonoids analysis, Beer analysis
- Abstract
Nutritional therapy, for example through beer, is the best solution to human chronic diseases. In this article, we demonstrate the physiological mechanisms of the functional ingredients in beer with health-promoting effects, based on the PubMed, Google, CNKI, and ISI Web of Science databases, published from 1997 to 2024. Beer, a complex of barley malt and hops, is rich in functional ingredients. The health effects of beer against 26 chronic diseases are highly similar to those of barley due to the physiological mechanisms of polyphenols (phenolic acids, flavonoids), melatonin, minerals, bitter acids, vitamins, and peptides. Functional beer with low purine and high active ingredients made from pure barley malt, as well as an additional functional food, represents an important development direction, specifically, ginger beer, ginseng beer, and coix-lily beer, as consumed by our ancestors ca. 9000 years ago. Low-purine beer can be produced via enzymatic and biological degradation and adsorption of purines, as well as dandelion addition. Therefore, this review paper not only reveals the physiological mechanisms of beer in overcoming chronic human diseases, but also provides a scientific basis for the development of functional beer with health-promoting effects.
- Published
- 2024
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- View/download PDF
136. Elicitors directed in vitro growth and production of stevioside and other secondary metabolites in Stevia rebaudiana (Bertoni) Bertoni.
- Author
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Ghazal B, Fareed A, Ahmad N, Azra, Salmen SH, Ansari MJ, Zeng Y, Farid A, Jenks MA, and Qayyum A
- Subjects
- Secondary Metabolism, Flavonoids metabolism, Flavonoids analysis, Phenols metabolism, Sodium Chloride pharmacology, Purines metabolism, Proline metabolism, Polyethylene Glycols pharmacology, Polyethylene Glycols chemistry, Benzyl Compounds, Stevia metabolism, Stevia growth & development, Stevia drug effects, Diterpenes, Kaurane metabolism, Glucosides metabolism, Plant Shoots metabolism, Plant Shoots growth & development, Plant Shoots drug effects, Gibberellins metabolism, Antioxidants metabolism
- Abstract
Stevia rebaudiana (stevia) is a plant in the Asteraceae that contains several biologically active compounds including the antidiabetic diterpene glycosides (e.g. stevioside, rebaudioside and dulcoside) that can serve as zero-calorie sugar alternatives. In this study, an elicitation strategy was applied using 5% polyethylene glycol (PEG), sodium chloride (NaCl; 50 and 100 mM) and gibberellic acid (2.0 and 4.0 mg/L GA
3 ) to investigate their effect on shoot morphogenesis, and the production of phenolics, flavonoids, total soluble sugars, proline and stevioside, as well as antioxidant activity, in shoot cultures of S. rebaudiana. Herewith, the media supplemented with 2 mg/L and 4 mg/L GA3 exhibited the highest shooting response (87% and 80%). The augmentation of lower concentrations of GA3 (2 mg/L) in combination with 6-benzylaminopurine (BAP) resulted in the maximum mean shoot length (11.1 cm). The addition of 100 mM NaCl salts to the media led to the highest observed total phenolics content (TPC; 4.11 mg/g-DW compared to the control 0.52 mg/g-DW), total flavonoids content (TFC; 1.26 mg/g-DW) and polyphenolics concentration (5.39 mg/g-DW) in shoots cultured. However, the maximum antioxidant activity (81.8%) was observed in shoots raised in media treated with 50 mM NaCl. The application of 2 mg/L of GA3 resulted in the highest accumulation of proline (0.99 μg/mL) as compared to controls (0.37 μg/mL). Maximum stevioside content (71 µL/mL) was observed in cultures supplemented with 100 mM NaCl and 5% PEG, followed by the 4 mg/L GA3 treatment (70 µL/mL) as compared to control (60 µL/mL). Positive correlation was observed between GA3 and stevioside content. Notably, these two compounds are derived from a shared biochemical pathway. These results suggest that elicitation is an effective option to enhance the accumulation of steviosides and other metabolites and provides the groundwork for future industrial scale production using bioreactors., (© 2024. The Author(s).)- Published
- 2024
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137. Health-promoting compounds in Amomum villosum Lour and Amomum tsao-ko : Fruit essential oil exhibiting great potential for human health.
- Author
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Imran S, Bibi Y, Yang LE, Qayyum A, He W, Yang J, Yang X, Pu X, Li X, and Zeng Y
- Abstract
The Zingiberaceae family serves as a diverse repository of bioactive phytochemicals, comprising approximately 52 genera and 1300 species of aromatic perennial herbs distinguished by their distinct creeping horizontal or tuberous rhizomes. Amomum villosum Lour. and Amomum tsao-ko Crevost & Lemaire., are the important plants of family Zingiberaceae that have been widely used in traditional medicine for the treatment of many ailments. The Amomum species are employed for their aromatic qualities and are valued as spices and flavorings. In the essential oils (EOs) of Amomum species, notable constituents include, camphor, methyl chavicol, bornyl acetate, trans -p-(1-butenyl) anisole, α-pinene, and β-pinene., Objective: The aim of this review is to present an overview of pharmacological studies pertaining to the extracts and secondary metabolites isolated from both species. The foremost objective of review is not only to increase the popularity of Amomum as a healthy food choice but also to enhance its status as a staple ingredient for the foreseeable future., Result: We endeavored to gather the latest information on antioxidant, antidiabetic, anticancer, antiobesity, antimicrobial, and anti-inflammatory properties of plants as well as their role in neuroprotective diseases. Research conducted through in-vitro studies, animal model, and compounds analysis have revealed that both plants exhibit a diverse array health promoting properties., Conclusion: the comprehensive review paper provides valuable insights into the diverse range of bioactive phytochemicals found in A. villosum and A. tsao-ko , showcasing their potential in preventing diseases and promoting overall human well-being. The compilation of information on their various health-enhancing properties contributes to the broader understanding of these plants and their potential applications in traditional medicine and beyond., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors.)
- Published
- 2024
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138. Geographic differences and variation of functional components of brown rice in 690 mini-core collections from global germplasms.
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Yang X, Nabi Mandal MS, Diao H, Du J, Pu X, Li X, Yang J, Zeng Y, Li Z, Li J, Hossain A, and Ali MK
- Abstract
Objective: To understand the geographic differences and variations in the functional components of brown rice cores collected from global rice germplasms., Methods: Four functional components, γ-aminobutyric acid (GABA), resistant starch (RS), total flavonoids, and alkaloids, in brown rice from 690 mini-core collections from 31 countries from five continents and the International Rice Research Institute, were analyzed using a spectrophotometry colorimetric method, and the results were statistically validated., Conclusion: The highest average amounts of functional components were obtained in Asian germplasms, except for GABA, and total flavonoids were highest in brown rice from Europe and Oceania, followed by Asia. The highest coefficient of variation for GABA was observed in Asia; that for RS and total flavonoids was observed in Africa, followed by Asia; and that for alkaloids was observed in America, followed by Asia. Overall, Asian countries were the most prominent and representative zones with the highest genotypic potential for functional components of brown rice. Forty-one rice accessions with enriched functional components originated mostly from biodiversity-rich areas in China, followed by those in the Philippines. Late sowing favored the enrichment of these components in brown rice. The current study provides a reference for rice breeding with enriched functional constituents, and guidelines for screening functional rice that could be used for human chronic disease research., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors. Published by Elsevier Ltd.)
- Published
- 2023
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139. Social-path embedding-based transformer for graduation development prediction.
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Yang G, Ouyang Y, Ye Z, Gao R, and Zeng Y
- Abstract
As the education of students attracts more and more attention, the task of graduation development prediction has gradually become a hot topic in academia and industry. The task of graduation development prediction aims to predict the employment category of students in advance via academic achievement data, which can help administrators understand students' learning status and set up a reasonable learning plan. However, existing research ignores the potential impact of social relationships on students' graduation development choices. To fully explore social relationships among students, we propose a Social-path Embedding-based Transformer Neural Network (SPE-TNN) for the task of graduation development prediction in this paper. Specifically, SPE-TNN is divided into the Social-path selection layer, the Social-path embedding layer, the Transformer layer, and the Multi-layer projection layer. Firstly, the Social-path selection layer is designed to find social relationships that impact graduation development and embed them into the student's performance features through the Social-path embedding layer. Secondly, the Transformer layer is adopted to balance the weights of the students' features. Finally, the Multi-layer projection layer is used to achieve the student graduation development prediction. Experimental results on the real-world datasets show that SPE-TNN outperforms the existing popular approaches., (© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2022.)
- Published
- 2022
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140. Hypericin-mediated photodynamic therapy for the treatment of cancer: a review.
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Dong X, Zeng Y, Zhang Z, Fu J, You L, He Y, Hao Y, Gu Z, Yu Z, Qu C, Yin X, Ni J, and Cruz LJ
- Subjects
- Antineoplastic Agents pharmacology, Humans, Perylene pharmacology, Photosensitizing Agents, Signal Transduction drug effects, Anthracenes pharmacology, Molecular Targeted Therapy methods, Neoplasms classification, Neoplasms metabolism, Neoplasms therapy, Perylene analogs & derivatives, Photochemotherapy methods
- Abstract
Objectives: Hypericin is a polycyclic aromatic naphthodianthrone that occurs naturally. It is also an active ingredient in some species of the genus Hypericum. Emerging evidence suggests that hypericin has attracted great attention as a potential anticancer drug and exhibits remarkable antiproliferative effect upon irradiation on various tumour cells. This paper aims to summarise the anticancer effect and molecular mechanisms modulated by hypericin-medicated photodynamic therapy and its potential role in the cancer treatment., Key Findings: Hypericin-medicated photodynamic therapy could inhibit the proliferation of various tumour cells including bladder, colon, breast, cervical, glioma, leukaemia, hepatic, melanoma, lymphoma and lung cancers. The effect is primarily mediated by p38 mitogen-activated protein kinase (MAPK), JNK, PI3K, CCAAT-enhancer-binding protein homologous protein (CHOP)/TRIB3/Akt/mTOR, TRAIL/TRAIL-receptor, c-Met and Ephrin-Eph, the mitochondria and extrinsic signalling pathways. Furthermore, hypericin-medicated photodynamic therapy in conjunction with chemotherapeutic agents or targeted therapies is more effective in inhibiting the growth of tumour cells., Summary: During the past few decades, the anticancer properties of photoactivated hypericin have been extensively investigated. Hypericin-medicated photodynamic therapy can modulate a variety of proteins and genes and exhibit a great potential to be used as a therapeutic agent for various types of cancer., (© The Author(s) 2020. Published by Oxford University Press on behalf of Royal Pharmaceutical Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2021
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141. Strategies of Functional Foods Promote Sleep in Human Being.
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Zeng Y, Yang J, Du J, Pu X, Yang X, Yang S, and Yang T
- Abstract
Sleep is a vital segment of life, however, the mechanisms of diet promoting sleep are unclear and are the focus of research. Insomnia is a general sleep disorder and functional foods are known to play a key role in the prevention of insomnia. A number of studies have demonstrated that major insomnia risk factors in human being are less functional foods in dietary. There are higher functional components in functional foods promoting sleep, including tryptophan, GABA, calcium, potassium, melatonin, pyridoxine, L-ornithine and hexadecanoic acid; but wake-promoting neurochemical factors include serotonin, noradrenalin, acetylcholine, histamine, orexin and so on. The factors promoting sleep in human being are the functional foods include barley grass powder, whole grains, maca, panax, Lingzhi, asparagus powder, lettuce, cherry, kiwifruits, walnut, schisandra wine, and milk; Barley grass powder with higher GABA and calcium, as well as potassium is the most ideal functional food promoting sleep, however, the sleep duration for modern humans is associated with food structure of ancient humans. In this review, we put forward possible mechanisms of functional components in foods promoting sleep. Although there is clear relevance between sleep and diet, their molecular mechanisms need to be studied further.
- Published
- 2014
- Full Text
- View/download PDF
142. [Characteristics of Yunnan Province rice landrace core collections under phosphorus deficiency].
- Author
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Shen S, Zeng Y, Pu X, Du J, and Li S
- Subjects
- Breeding, China, Genetic Variation, Oryza genetics, Oryza physiology, Phosphorus metabolism, Soil analysis
- Abstract
Soil phosphorus (P) deficiency is a major yield-limiting factor in rice production. Employing 526 rice landrace accessions from 5 rice-planting regions and 16 prefectures in Yunnan Province, this paper studied their P-deficiency tolerance characteristics by comparing the relative plant dry weight under acid red soil condition. The results showed that Northwest Yunnan cold highland japonica rice-planting region was most abundant in P-deficiency tolerance core collection of indica, and there was no significant difference in japonica among five ecological zones of rice landraces. Nujiang, Lijiang, Dehong, Wenshan, Xishuangbana and Yuxi were most abundant in P-deficiency tolerance core collection of indica, and Lijiang, Wenshan and Chuxiong were most abundant in P-deficiency tolerance core collection of japonica. Indica had a higher P-deficiency tolerance than japonica. The P-deficiency tolerance of rice was significantly related with its genetic diversity, rice breeding and acid red soils.
- Published
- 2005
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