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Background: Double‐chambered left ventricle (DCLV) is extremely rare. Challenges remain in accurate diagnosis of DCLV by echocardiography, because it is easily confused with left ventricular diverticulum, left ventricular aneurysm, ventricular septal defect, etc. Herein, we reviewed echocardiographic characteristics of DCLV and evaluated the accuracy of echocardiographic diagnosis. Methods: Clinical and echocardiographical databases of two heart centers were reviewed. Nine children with DCLV of superior–inferior arrangement were studied retrospectively. Results: Normal elliptical geometry of LV cavity is preserved in DCLV. Fibromuscluar bundles separate LV into the main chamber and the accessory chamber. The associated malformations included ventricular septal defects, mitral regurgitation, mitral valve stenosis, pulmonary stenosis, and left ventricular noncompaction in our study. Eight of nine subjects with DCLV of superior–inferior arrangement were diagnosed correctly by initial echocardiographic examination, and one case was mistaken as left ventricular diverticulum. Conclusions: Double‐chambered left ventricle could be diagnosed and followed up by echocardiography. The morphological classification is a simplified way to improve diagnostic accuracy. [ABSTRACT FROM AUTHOR]

Objectives: FOSL1 is overexpressed in multiple cancers including malignant glioma and contributes to different cellular processes. However, little attention has been paid to the lower grade glioma (LGG). Methods: Cox coefficients were examined to compare FOSL1 expression among different tumors types using OncoLnc. The UCSC Xena browser was used to generate Kaplan-Meier survival curves and explore the association between FOSL1 expression and overall survival (OS) in TCGA-LGG and subgroups. Results: FOSL1 expression in LGG was ranked first among 21 different cancers. LGG with lower FOSL1 expression had longer OS (P < 0.001). The astrocytoma group had the highest FOSL1 expression and shortest OS, followed by oligoastrocytoma and oligodendroglioma (P < 0.05). The 1p19q co-deletion or IDH mutation subgroups had lower FOSL1 expression and longer OS (P < 0.001). Compared with the corresponding groups, LGG with lower FOSL1 expression had longer OS than the following groups: astrocytoma, oligodendroglioma, with/without 1p19q co-deletion, with IDH mutation, with radiation, and with pharmaceutical therapy (P < 0.05). Discussion: FOSL1 is a prognostic marker in LGG and subgroups. [ABSTRACT FROM AUTHOR]

With the development of avionics systems, it is particularly important to rely on the network to build multi-platform avionics resources including different aircraft avionic resources. By comprehensively utilizing the resources of different flight platforms, the advantages of different platform resources can be utilized and cooperation is used to enhance the task handling ability. Resource management and task scheduling of multi-platform avionics systems are their core functions. In order to simulate and verify the resource management function of multi-platform avionics systems and further study the resource scheduling method, the paper studies the modeling method and the scheduling algorithm of multi-platform avionic resources. The paper reasonably schedules hardware resources on multi-platform avionics systems to increase the task acceptance rate. Firstly, multi-platform avionics resources are modeled by multi-level hierarchical topology, and the requirements of multi-platform avionics tasks are analyzed. Secondly, based on the SST (Sliding-Scheduled Tenant) adaptive scheduling algorithm, factors such as sensors and priorities are added to achieve higher acceptance rate. The algorithm completes a series of task requests in the demand allocation process of avionic resources. Finally, the algorithm is implemented in CloudSim simulation environment. The experimental results are analyzed comprehensively from different scenarios, which show that the proposed algorithm has a higher request acceptance rate than the original algorithm. [ABSTRACT FROM AUTHOR]

Objective: Clinical decision making in children with heart disease relies on detailed measurements of cardiac structures using two-dimensional and M-mode echocardiography. However, no echocardiographic reference values are available for the Chinese children. We aimed to establish z-score regression equations for left heart structures in a population-based cohort of healthy Chinese Han children.Method: Echocardiography was performed in 545 children with a normal heart. The dimensions of the aortic valve annulus (AVA), aortic sinuses of Valsalva (ASV), sinotubular junction (STJ), ascending aorta (AAO), left atrium (LA), mitral valve annulus (MVA), interventricular septal end-diastolic thickness (IVSd), interventricular septal end-systolic thickness (IVSs), left ventricular end-diastolic diameter (LVIDd), left ventricular end-systolic diameter (LVIDs), left ventricular posterior wall end-diastolic thickness (LVPWd), left ventricular posterior wall end-systolic thickness (LVPWs) were measured. Regression analyses were conducted to relate the measurements of left heart structures to body surface area (BSA). Left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) were calculated. Several models were used, and the adjusted R2 values were compared for each model.Results: AVA, ASV, STJ, AAO, LA, MVA, IVSd, IVSs, LVIDd, LVIDs, LVPWd, and LVPWs had a cubic relationship with BSA. LVEF and LVFS fell within a narrow range.Conclusions: Our results provide reference values for z scores and regression equations for left heart structures in Han Chinese children. These data may help make a quick and accurate judgment of the routine clinical measurement of left heart structures in children with heart disease. [ABSTRACT FROM AUTHOR]

Objective: Ventricular function assessment is very important for the treatment and prognostic classification of children with a single right ventricle (SRV) after cavopulmonary anastomosis (CPA). However, unusual ventricular shapes can result in inaccurate measurements. The aim of this study was to evaluate velocity vector imaging (VVI) for assessing segmental ventricular function in children with SRV after CPA.Methods: Twenty-one children with SRV after CPA and 21 age- and sex-matched children with normal biventricular anatomy and function were included. The longitudinal velocity, displacement, strain and strain rate were measured in the two groups in six segments by VVI. The velocity, displacement, strain and strain rate of the SRVs were compared with max(dp/dt) measured during simultaneous cardiac catheterization in the SRV subjects.Results: The control group consisted of 13 males and 8 females (69% males) with a mean age of 6.7 ± 3.5 years and mean weight of 20.5 ± 6.5 kg, and the study group consisted of 13 males and 8 females with a mean age 6.7 ± 3.7 years and mean weight of 20.6 ± 6.8 kg. Age, weight and sex distribution were similar between the groups (all, p > .05). Strain and strain rate values in all six segments were significantly lower in the study group than in the control group (all, p < .05). The max(dp/dt) of the SRV was 522.84 ± 158.32 mmHg/s, and the strain rate of the basal segment at the rudimentary chamber correlated best with max(dp/dt) (r = 0.74, p < .01).Conclusions: Segmental ventricular dysfunction was present in children with SRV after CPA, and it could be assessed using VVI. [ABSTRACT FROM AUTHOR]

Background: Challenges remain in quantitative evaluation of right ventricular (RV) function by echocardiography. Multiple‐view assessment is believed to provide a more comprehensive quantification of RV function than conventional single‐view analysis. Peak systolic longitudinal RV strain (RVLS) measured by speckle tracking echocardiography (STE) has clinical and prognostic value. No study has investigated RV systolic function in the repaired tetralogy of Fallot (rTOF) using a standardized four‐view iRotate model from one apical view. Herein, we examined the feasibility and accuracy of the four‐view analysis from apical window in quantitation of RVLS among children with rTOF. Methods: Thirty‐seven children with rTOF and 37 age‐ and gender‐matched controls were prospectively enrolled. Tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (TDI‐S′) and fractional area change(FAC) were obtained. RVLS of four free‐walls were analyzed by dedicated RV speckle tracking software. Echocardiographic parameters were compared with the right ventricular ejection fraction (RVEF) measured by the cardiac magnetic resonance (CMR) in children with rTOF. Results: Multi‐view RVLS analysis from apical window was feasible in 35 children with rTOF and all the controls. Compared with age‐ and gender‐matched controls, RVLS of the anterior, lateral, inferior‐a, and inferior‐b walls were significantly reduced in children with rTOF (P < 0.001). RVLS of the anterior, lateral, inferior‐a, and inferior‐b walls correlated well with CMR‐RVEF in children with rTOF (r = −0.667, −0.743, −0.808, −0.695, P < 0.001). Conclusions: Multi‐view analysis of RVLS from apical window can be applied to evaluate the RV function in children with rTOF. RVLS of the inferior wall‐a in the aortic view is a novel and accurate indicator of RV function because of its good reproducibility and strong correlation with CMR‐RVEF. [ABSTRACT FROM AUTHOR]

To test the relationship between social face consciousness (SFC) and life satisfaction (LS) among new employees in a Chinese context, we administered the Consciousness of Social Face Scale, the Satisfaction With Life Scale, the Perceived Social Support Scale, and the Ruminative Responses Scale to 624 employees with 1 year or less of service in the job market. The results showed that SFC had a significant negative predictive effect on new employees' LS, and indirectly affected new employees' LS through perceived social support. Further, rumination played a significant role in moderating the influence of SFC on new employees' LS; specifically, for new employees with a low level of rumination, SFC had no significant predictive effect on LS, whereas for those with a high level of rumination, SFC had a significant negative predictive effect on their LS. Thus, SFC inhibits new employees' LS and affects LS through the intermediary role of perceived social support, while rumination moderates this relationship. This study provides insight into how new employees can improve their LS in practice. [ABSTRACT FROM AUTHOR]