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This paper digests the influences of financial transparency and media coverage in the Chinese stock market. In China, media performs under a regulatory system and media information is regarded as the direction of news. In addition, the Chinese market is dominated by retail investors and financial information is always manipulated, so the reliability of financial information is quite intriguing. The effect of ostensible financial information on the stock market through the media hype is a crucial issue. We employ media and transparency to analyze over 3,000 stocks in China. First of all, the Chinese stock market is characterized by significantly negative momentum profit and thus exhibits price reversal. However, when high media coverage and high transparency jointly come into play, the significantly negative momentum profit turns to be significantly positive. This dramatic change alters the price reversal to be price momentum. By contrast, low media coverage and low transparency still result in price reversal. [ABSTRACT FROM AUTHOR]

The aim of this paper is to numerically investigate the energy extraction performance of a flexible hydrofoil under the semi-activated mode. The effects of flexure amplitude (α), pitching amplitude (θ 0) and reduced frequency (f∗) on power extraction were studied and compared with rigid hydrofoils. The evolution of effective angle of attack, vortex and pressure field are examined. The results show that averaged power coefficient ( C P ¯) and efficiency (η) of the flexible hydrofoil are better than that of rigid hydrofoils. The increase of α can obviously improve the zones of high η at 0.15 < f∗ <0.25 and 50° < θ 0 < 80°. Especially, increasing α could obviously improve C P ¯ and η at a low θ 0. Further, at a high θ 0 , the factors causing decline of power extraction are the separation of leading-edge vortex at low frequency and the shifting of pressure center caused by the decrease of pitching angular rate at high frequency. Compared with the rigid hydrofoil, the flexible hydrofoil can increase the pressure difference between the upper and lower surfaces of hydrofoils, thus lift is improved, which is beneficial to the improvement of energy extraction performance. • The energy extraction of a flexible hydrofoil in semi-activated mode was studied. • A flexible hydrofoil improves the energy extraction power and efficiency. • The high efficiency zone is enlarged by increasing flexure amplitude. • At low frequency leading-edge vortex separation causes energy extraction decline. • At high frequency the pressure center shifting causes energy extraction decline. [ABSTRACT FROM AUTHOR]

Background: Osteoporotic vertebral compression fractures (OVCF) severely affect the quality of life in the aged population. Percutaneous vertebroplasty (PVP) alleviates pain and stabilizes vertebrae, but suboptimal bone cement distribution can cause complications. Hence, this study aimed to clarify whether a new technique for PVP, using a curved guide wire, enhances the distribution of bone cement and improves clinical outcomes in patients with OVCF. Methods: Patients with single-segment OVCF underwent PVP or curved guide wire percutaneous vertebroplasty (C-PVP). Propensity score matching (PSM) was employed to balanced the baseline characteristics. The primary outcomes were the visual analog scale (VAS) and Oswestry disability index (ODI) scores. The secondary outcomes included assessments of bone cement distribution, bone cement injection volume, radiological parameters, and general clinical results. Additionally, Complications and adverse events were documented. Results: After PSM analysis, each group comprised 54 patients, which significantly reduced baseline differences. The C-PVP group showed better clinical outcomes compared to the traditional PVP group. One month after surgery, the C-PVP group had significantly lower VAS and ODI scores (p < 0.001). These improvements persisted at six months and the final follow-up. Additionally, bone cement distribution scores were better (p < 0.001), injection volume was higher (p = 0.03), leakage was less frequent (p = 0.02), and adjacent vertebral fractures occurred less frequently (p = 0.04) in the C-PVP group. Radiological parameters and overall clinical outcomes revealed no significant differences between the two groups. Conclusion: The use of curved guide wire in PVP significantly improves bone cement distribution and injection volume, resulting in better clinical efficacy in patients with OVCF. [ABSTRACT FROM AUTHOR]

Fu, T. and Zhang, Y., 2020. Optimal decision model design of diversified port investment. In: Yang, Y.; Mi, C.; Zhao, L., and Lam, S. (eds.), Global Topics and New Trends in Coastal Research: Port, Coastal and Ocean Engineering. Journal of Coastal Research, Special Issue No. 103, pp. 159–162. Coconut Creek (Florida), ISSN 0749-0208. In order to solve the problem of low profit in the traditional optimal decision model of diversified port investment, a new optimal decision model of diversified port investment is designed. Firstly, the investment decision -making index system of major stakeholders is constructed, in which the major stakeholders include the government, investors, creditors, contractors, operators, and so on. Carry on hinterland area analysis and hinterland goods quantity forecast. Then, the constraints of the optimal decision model for diversified port investment are determined, including cost-benefit constraints, ecological carrying capacity constraints, supply and demand constraints, integer programming constraints. Finally, the optimal decision model of diversified port investment is constructed according to the given constraints. The model consists of demand forecasting module, income module, cost module and investment and financing module. In order to prove that the profit performance of the optimized decision model is good, the traditional model is compared with the model. The experimental results show that the model is better than the traditional model. [ABSTRACT FROM AUTHOR]

Epidermal growth factor receptor variant III (EGFRvIII) is prominently expressed in various epithelial tumors. PD0721, a single-chain antibody (scFv), has been developed to specifically target EGFRvIII. Although doxorubicin (DOX) is an essential treatment approach for glioblastoma (GBM), its toxic effects and limited targeting capabilities are a challenge. To overcome the above limitations, antibody-drug conjugates (ADCs) have been developed to exploit the specificity of monoclonal antibodies in directing potent cytotoxic drugs to tumor cells expressing the target antigens. The present study aimed to conjugate DOX with PD0721 scFv to construct a PD0721-DOX ADC targeting EGFRvIII and examine its targeting effect and in vitro anti-GBM activity. PD0721-DOX ADC was generated by combining PD0721 scFv with DOX, using dextran T-10 as a linker. The drug-to-antibody ratio (DAR) was measured by ultraviolet and visible spectrophotometry (UV-Vis). A series of techniques, including cytotoxicity assays, immunofluorescence, cell internalization and flow cytometry assays were employed to evaluate the targeting efficacy and anti-GBM activity of the PD0721-DOX ADC. Following the conjugation of PD0721 scFv with DOX, the UV-Vis results showed a noticeable red shift in the maximum absorbance. The DAR of PD0721 scFv and DOX was 9.23:1. Cytotoxicity assays demonstrated that DK-MG cells treatment with PD0721-DOX ADC at 10 and 20 µg/ml significantly increased cytotoxicity compared with U-87MG ATCC cells (all P<0.01). Confocal microscopy revealed distinct green and red fluorescence in EGFRvIII-expressing DK-MG cells, while no fluorescence was observed in EGFRvIII negative U-87MG ATCC cells. Furthermore, compared with U-87MG ATCC cells, DK-MG cells showed effective internalization of the PD0721-DOX ADC (P<0.001). Finally, flow cytometric analyses indicated that the PD0721-DOX ADC significantly promoted the apoptosis of DK-MG cells compared with U-87MG ATCC cells (P<0.01). In summary, the current study suggested that the PD0721-DOX ADC could exhibit a notable targeting efficacy and potent anti-GBM activity. [ABSTRACT FROM AUTHOR]

Building construction requires important amounts of freshwater, thus depleting the already stressed natural water resources. This issue could be addressed by using recycled water in construction and in building systems. However, integrating greywater recycling systems is limited by complexity, costs, vulnerability to environmental fluctuations, and coordination of policymakers, developers, and construction practitioners. Here, we review recycled water systems in buildings with focus on case studies of successful implementations, policies, recycled water treatment in buildings, and health aspects. Compared to conventional tap water, the incorporation of recycled water enhances the consistency and workability of reclaimed water concrete by 12–14%, and it increases concrete viscosity by 11% and yield stress by 25%. We discuss the intricacies of building water recycling systems, with emphasizing on conserving water, mitigating environmental impact, and enhancing economic efficiency. Challenges include water quality assurance, dual piping infrastructure, and regulatory compliance. Government interventions, including incentives, mandates, and subsidy policies, emerge as drivers for widespread adoption. Technological advancements, such as membrane filtration and advanced oxidation processes, are examined for strengths and limitations. [ABSTRACT FROM AUTHOR]

The creation of affordable, long-lasting, and effective electrocatalysts is a significant research issue in the area of water splitting. In this work, Ru-modified CoP x spearhead on nickel foam (Ru-CoP x /NF) is fabricated by simple hydrothermal, impregnation and subsequent low-temperature phosphorization process. The incorporation of Ru into the Co-P structure enables the effective reconstruction of the electronic coordination environment. The Ru-CoP x /NF catalyst performs well for hydrogen evolution reaction (HER), achieving a current density of 10 mA cm−2 with low overpotentials of 41 mV and outstanding stability in 1 M KOH. Furthermore, the produced CoP x /NF has low overpotential of 280 mV, allowing 10 mA cm−2 for the oxygen evolution reaction (OER) in 1 M KOH. In addition, the developed asymmetric Ru-CoP x /NF||CoP x /NF electrolyzer could drive 10 mA cm−2 in alkaline electrolyte with a low cell voltage of 1.51 V. Surprisingly, water-splitting may be efficiently by renewable energy sources, presenting a viable strategy for lowering the cost of creating hydrogen energy. The synthesized Ru-CoP x /NF exhibits excellent electrocatalytic performance for HER, with low overpotentials of 41, 73 and 168 mV, driving 10 mA cm−2 in alkaline, acidic and neutral media, respectively. The synthesized CoP x /NF without Ru has excellent OER performance, with an overpotential of only 280 mV@10 mA cm−2. The Ru-CoP x /NF||CoP x /NF electrolyzer can be powered by sustainable energies. [Display omitted] • The spearhead-like nanostructures provide abundant active sites. • The introduction of Ru optimized the reaction kinetics for HER. • The prepared catalysts exhibit excellent catalytic performance for HER and OER. [ABSTRACT FROM AUTHOR]

Nitrogen doped carbon nanosheets supported RuM (RuM/NCN) presents excellent electrocatalytic performance for HER in Wide pH Range. The assembled electrolyzer shows remarkable catalytic performance and stability in alkaline electrolyte and alkaline seawater. [Display omitted] Developing efficient electrocatalysts for hydrogen evolution reaction (HER) in full pH range can promote the practical applications of hydrogen energy. In this work, nitrogen doped carbon nanosheets supported RuM (Mo, W, Cr) (RuM/NCN) are prepared through an ultrafast microwave approach. The carbon nanosheet structure coupled with the ultrasmall RuM nanoparticles can expose rich active sites to optimize the catalytic activity. Moreover, the strong metal-support interactions also favor to accelerate the reactions kinetics and improve stability. Thus, the developed RuMo/NCN (RuW/NCN) show excellent HER catalytic activities with overpotentials of 72 (75) mV, 82 (82) mV and 124 (1 1 9) mV to reach current density of 10 mA cm -2 in 1 M KOH, 0.5 M H 2 SO 4 and alkaline seawater, respectively, and also achieve excellent performance in 1 M PBS. This work provides a valid and novel avenue to design efficient electrocatalysts in renewable energy-related fields. [ABSTRACT FROM AUTHOR]